LOCUS       gnlProkkaKAALHNMO_101   3145 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KAALHNMO_101.
ACCESSION   gnlProkkaKAALHNMO_101
VERSION     gnlProkkaKAALHNMO_101
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 12:00:14
            Original ID  :: gnl|Prokka|KAALHNMO_101
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3145
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3145
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[106:3145]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      107..3145
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..3145
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3145
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             107..3145
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     3.8e-92. Score: 300.7. Matches aSDomain:
                     nrpspksdomains_ctg84_1_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-864). E-value:
                     1.1e-112. Score: 368.5. Matches aSDomain:
                     nrpspksdomains_ctg84_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (966-1013). E-value: 3.9e-16. Score:
                     50.9. Matches aSDomain: nrpspksdomains_ctg84_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     241; E-value: 4.8e-73)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_1"
                     /sec_met_domain="Condensation (E-value: 2e-79, bitscore:
                     252.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-125, bitscore:
                     404.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6e-11, bitscore:
                     29.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTL
                     EGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQA
                     SIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDP
                     LPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSAS
                     RDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKD
                     LHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQN
                     TLFSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAF
                     TLHGLFERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSER
                     SPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLE
                     VDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFP
                     LSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAIHQENVTTAH
                     FIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTE
                     ATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVAR
                     GYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPG
                     EIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLERLLPGYMVPAYMIE
                     MEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNF
                     FDRGGHSLKATALVSRIAKEFDVQ"
     aSDomain        116..1006
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg84_1_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="3.80E-92"
                     /label="ctg84_1_Condensation_Starter.1"
                     /locus_tag="ctg84_1"
                     /protein_end="300"
                     /protein_start="3"
                     /score="300.7"
                     /tool="antismash"
                     /translation="HTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIP
                     FKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPD
                     QPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDT
                     IILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     aSModule        116..3145
                     /complete
                     /domains="nrpspksdomains_ctg84_1_Condensation_Starter.1"
                     /domains="nrpspksdomains_ctg84_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg84_1_PCP.1"
                     /locus_tags="ctg84_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       185..301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0001"
                     /evalue="2.70E-08"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg84_1"
                     /protein_end="65"
                     /protein_start="26"
                     /score="26.5"
                     /tool="antismash"
                     /translation="ICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLE"
     CDS_motif       506..571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0002"
                     /evalue="1.00E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg84_1"
                     /protein_end="155"
                     /protein_start="133"
                     /score="24.8"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNVMGNQIIDLY"
     CDS_motif       905..994
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0003"
                     /evalue="1.30E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg84_1"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.2"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       1046..1159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0004"
                     /evalue="5.10E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg84_1"
                     /protein_end="351"
                     /protein_start="313"
                     /score="28.7"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQY"
     aSDomain        1496..2698
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg84_1_AMP-binding.1"
                     /evalue="1.10E-112"
                     /label="ctg84_1_AMP-binding.1"
                     /locus_tag="ctg84_1"
                     /protein_end="864"
                     /protein_start="463"
                     /score="368.5"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNE
                     SIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSA
                     PNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSF
                     LTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAI
                     HQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVK
                     IR"
     CDS_motif       1682..1723
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0005"
                     /evalue="6.30E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg84_1"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.2"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       1907..1966
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0006"
                     /evalue="4.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg84_1"
                     /protein_end="620"
                     /protein_start="600"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       2492..2581
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0007"
                     /evalue="6.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg84_1"
                     /protein_end="825"
                     /protein_start="795"
                     /score="56.9"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       2663..2728
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg84_1_0008"
                     /evalue="5.50E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg84_1"
                     /protein_end="874"
                     /protein_start="852"
                     /score="40.7"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
     aSDomain        3005..3145
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg84_1_PCP.1"
                     /evalue="3.90E-16"
                     /label="ctg84_1_PCP.1"
                     /locus_tag="ctg84_1"
                     /protein_end="1013"
                     /protein_start="966"
                     /score="50.9"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQ"
ORIGIN
        1 atagtgcata tatggattat atagtcatat aatttctttt attgtcattt ttctgctttt
       61 ttctacattt tcttatcctc ttattatgag aactggaggg aatccgttga gcgaacatac
      121 ttattcttta acccatgccc aaaggagagt gtggtttacc gaactgctgg agccagatac
      181 cagcatttgc aatcttacag cttgtgtgaa atttaaaggc aatattgagc ttgatactct
      241 ggagggagca ctgaatcatt ccatctcccg caacgacgcc attagatttc agctgttaga
      301 aggagaagag cttgagcctc gattgcacct tactgaatat aaatattatc cacttagaat
      361 aattgatttt tcaaatgttg aaatgataga aatagagcaa tggattcagg atcaagcgag
      421 cattccattt aaactgttca actcgcctct ttttcaattt tacctcctta gaattgactc
      481 tcatgaagtt tggctatttg cgaaattcca tcatatcata atggatggaa tctctttaaa
      541 tgtgatggga aatcaaatta tagatcttta tcaaaaaatg aaaaagaaag atcctttacc
      601 tgatcagccg gaaccttctt acttgagcta catcgaaaaa gagagtcaat atctacaatc
      661 tccacggttt gcaaaggacc gtttattttg gacgcaaacc tttgagcacc cgttggaata
      721 ccactcgtta gccgaccaga cgtccttaca aaaacagagc acatctgcat ccagagacac
      781 catcattctt tcacctgatc tagagcaaac gattcgaatc ttctgcgaag aacacaagat
      841 caatatcatt tccttattta tggcttcatt ttacatatgc atcagccgaa tcacttctaa
      901 aaaagatctt gccattggca cctactatgg caacagaggt tcaaaggctg aaaaagaaat
      961 gctcggcatg ttcgttagtt cccttccaat cagaataacg gttgatcctg acacagattt
     1021 tctttccttt gtccgcacaa taggcaggga acagctttct gttatgcgtc atcaacggtt
     1081 tccttataat ttgcttgtaa atgaattaag aaatgaacag aaggatttac acaaccttat
     1141 cggtatatct atgcagtatc agccacttca gtggcacaat gcagatgatt ttgactatga
     1201 aacagcgctt tatttcagcg gatacaccgc gaacgaactt tcagttcaaa tacaagaacg
     1261 gatagacaat ggaaccattc aattaaattt cgactatcaa aataccttgt tttctcttga
     1321 ggatattaaa cgaatacaat ctcatctgct taccatactg gaaaacgccc ttaaacatcc
     1381 gcacagcttt ataagagaat tagatatgac gaatacaaga gaaaagcaaa aattgttgta
     1441 tgagtttaac aagacggaag ctgtttcgcc taaagctttc accctgcatg ggctgtttga
     1501 gcgacaggca gctttcacac cggagcggct ggccattcgc ttttcaggcg gttcgctgac
     1561 atacgctgag cttgatatgt acgccagccg gctggctgcg caccttgcgg cacgcggcgt
     1621 cacaaacgaa agtatcgtcg gtgtcctgtc tgaacgctca cctgacatgc tgatcgctgt
     1681 ccttgctgta ttgaaggccg gcggggcgta tttgccgctt gatcctgcgt atccaaagga
     1741 gcggctgagc tacatgctga aagacagcgg ggcatcgctc ttgctgacac agccgggatg
     1801 ctccgcacca aacttttctg gcgaaacgct tgaagtggac atgacatctc ttgcgagcga
     1861 aaaagcagaa aaccatgagt ttactcctgc tgacggcgga tctctcgcct atgtcatcta
     1921 tacatcgggc tctaccgggc agccgaaagg agtggccgtt gagcaccgtc aggctgtttc
     1981 ctttctgacc ggcatgcagc accagtttcc gctttcggaa gatgacattg tcatggtgaa
     2041 aacctctttt tcctttgatg cgtctgtgtg gcagctgttt tggtggtcgc tttccggtgc
     2101 ttcggcgtat ctgcttccgc ccggctggga gaaagactcc gcattgatcg tacaagccat
     2161 tcatcaggaa aacgtgacaa cggctcattt tattccggct atgctgaaca gctttctcga
     2221 tcaagcggaa atcgaaaggc tgagtgacag gacaagccta aagcgtgtat tcgccggagg
     2281 tgaaccgctt gcgccgcgta cggcagcccg ttttgcttct gtattgccgc aggtatcatt
     2341 aatccatggt tacgggccga cagaagcaac ggtagacgcg gcattttacg tattggatcc
     2401 agaacgggac agggatcgtt tgcggattcc gattgggaag cccgtacctg gtgcgcgttt
     2461 gtatgtttta gatccgcatt tagccgtaca gccttccggt gtcgccggcg aactgtacat
     2521 tgccggagcg ggtgttgcca gaggttattt gaatcggccg gcattaacgg aggagcgttt
     2581 tcttgaagac ccgttttacc cgggggaacg catgtacaaa accggggatg tggcgcgctg
     2641 gctccctgac gggaatgttg aattcctcgg gcgcacggat gatcaggtaa aaatccgcgg
     2701 ctaccggatt gagccgggag aaattgaagc ggcactaaga agcatagaag gcgtaagaga
     2761 ggcggctgtt accgtacgga cagacagcgg ggagccggaa ttatgcgctt atgtagaagg
     2821 gctccaaaga aacgaagtgc gtgcacagct tgagagactg ttgccgggct acatggtccc
     2881 agcctatatg atagagatgg aacagtggcc ggttacgcca agcggaaagc tcgaccgaaa
     2941 cgccctgcca gctcctggcg gagcggcaga tgcggagacc tacacggcgc cgagaaacgt
     3001 gactgagatg aagctttctc agctgtggga ggacgtgctg aaaaatggcc ctgtcgggat
     3061 tcacgacaac ttttttgacc gcgggggaca ttccttaaaa gcaacggcgc ttgtctcacg
     3121 gatcgccaaa gaattcgatg tacag
//
