LOCUS       gnlProkkaMMHBEFPG_57   11606 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMHBEFPG_57.
ACCESSION   gnlProkkaMMHBEFPG_57
VERSION     gnlProkkaMMHBEFPG_57
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 10:59:14
            Original ID  :: gnl|Prokka|MMHBEFPG_57
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11606
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..126
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_1"
                     /sec_met_domain="Subtilosin_A (E-value: 4e-30, bitscore:
                     97.6, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       1..30
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MAVIVENKGC"
                     /locus_tag="ctg48_1_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       31..126
                     /prepeptide="core"
                     /locus_tag="ctg48_1_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="26.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="ATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MAVIVENKGC"
                     /leader_location="[0:30](+)"
     protocluster    1..11606
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[0:1606]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..1606
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11606
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11606
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             260..1606
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_2"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 2.6e-30,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.7e-08, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.6e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.7e-11, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 8.5e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             1619..1780
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             1777..2496
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127.7; E-value:
                     9.5e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     CDS             2489..3799
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNYFAKKKN
                     WMFLLHAAIFACVCLSAAFMPAATIPLCAVHILWAVVIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVVYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     CDS             3765..4949
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_6"
                     /sec_met_domain="Peptidase_M16_C (E-value: 2.6e-06,
                     bitscore: 21.3, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQAKENGLEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYF
                     YGAAAYLKEQIIDAFGYAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKT
                     FADLSFPSSLSFEAFEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRK
                     DRIEAIHPKRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSGRIPVNRH
                     VFETETRSAAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAV
                     YHVITRYDVMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLL
                     QFDSPEGLLAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     CDS             4954..6234
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_7"
                     /sec_met_domain="Peptidase_M16 (E-value: 1.3e-14, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQAHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMVLGDEERMEDTWTGLQIGALPGQNDLLAIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHISQKEAIRQ"
     CDS             6231..6932
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     CDS             complement(6938..8314)
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNVSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGA
                     VSVIHTEEIDQVVYYAAQSDRCPDFSQMTVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPTDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDANTGQLVESIIDSFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     CDS             complement(8354..9709)
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLCFCEGEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAVYVIGIDTLTVDRSIPVEG
                     YDVAIDPNGLFAYVLNFGIVQKVDLTTGEVTGTIERELIVSTIETNWPERYAYVLEQEF
                     FFNYLTVIDLNTFTISSTQELEYEGEYRMFTSGAEVYLYDGFTGNLYSVSPNGAGVIGN
                     VPQSARDFAFTPNGEFLYATHVLEQSITVYNTDDYSVETVISLGVSPGAIAI"
     CDS             9939..11084
                     /locus_tag="ctg48_11"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEFFFKMSESYYYMKQTYFSMDY
                     ARQAYEIYKENEAYNIRLLQCHSLFATNFLDLKQYEDAVSHFQKAYSMAEAEKQPQLMG
                     RTLYNIGLCKNSQSQYEDAITYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKMDKA
                     HEYHSKGMAYSQKAGDVIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYADLEDFA
                     IDVAKYYHERKNFQKASAYFLKVEQVRQLIQGGVSLYEIEV"
     CDS             11068..11187
                     /locus_tag="ctg48_12"
                     /transl_table=11
                     /translation="MKLKSKLLLSCLALSTVFVATTIANAPTHQIEVAQRGMI"
ORIGIN
        1 aaagctgtca ttgtagaaaa caaaggttgt gcaacatgct cgatcggagc cgcttgtcta
       61 gtggacggtc ctatccctga ttttgaaatt gccggtgcaa caggtctatt cggtctatgg
      121 gggtaaggat ctcccaaaag ggcatagtca ttctactatg ccctttttaa gtaaattaca
      181 atttttaact aaaatctacc tcttggatat acatacacaa tcgtttttta tttgaatcat
      241 atgtataggg gatggtattt tgtttataga gcagatgttt ccatttatta atgaaagtgt
      301 aagagttcac cagcttcctg agggcggcgt gttagaaatc gactacttgc gcgataatgt
      361 ctccatttct gactttgagt atttggatct caacaaaacg gcttacgagc tttgcatgcg
      421 catggatggc caaaaaacag ctgagcagat tttagctgag caatgtgcag tgtatgatga
      481 atcaccggaa gaccataaag attggtatta cgacatgctc aacatgctcc agaacaagca
      541 ggttattcag cttggaaacc gggcaagccg ccataccatc accacgagcg gaagcaatga
      601 atttccgatg cccctgcacg ccacctttga actgacgcac cgctgtaatt tgaaatgcgc
      661 ccactgttat ttggaaagct cacctgaagc gctcggcacc gtgtcgattg agcaattcaa
      721 aaaaacggct gatatgctgt ttgataacgg tgtattgaca tgcgaaatca caggcgggga
      781 aatttttgtc catccaaacg ccaatgagat tcttgactat gtgtgtaaaa agttcaaaaa
      841 agtcgctgtc ttaacaaacg gaacactcat gcgaaaagag agcctggagc ttttgaagac
      901 ttacaagcaa aaaatcatcg tcggcatttc tcttgatagt gtcaattccg aggtccatga
      961 ctcctttaga gggagaaaag gctcttttgc ccaaacttgt aaaacgataa aattgttgag
     1021 tgaccacggt atatttgtca gagtcgccat gtctgtcttc gaaaaaaaca tgtgggaaat
     1081 ccacgatatg gcccaaaagg ttcgggatct cggggcgaag gcgttttctt acaattgggt
     1141 tgacgatttc ggaagaggca gggatattgt ccatccaacg aaagacgccg agcagcaccg
     1201 caagtttatg gaatacgagc aaaatgtgat tgatgagttt aaagatctga ttccgattat
     1261 tccttatgag agaaaacgcg cggcaaattg cggcgctggc tggaagtcca ttgtgatcag
     1321 cccgttcggc gaagtacgtc cttgcgccct ctttccaaag gaattttcat tgggaaatat
     1381 ttttcatgat tcctatgaaa gcatctttaa ctcccctctc gtccataaac tgtggcaagc
     1441 gcaggcgccg cggttcagcg aacattgcat gaaagacaaa tgcccgttca gcggctattg
     1501 cggaggctgt tacttaaaag ggctgaactc taacaaatat caccggaaaa acatttgctc
     1561 ttgggcgaaa aatgaacaat tagaagacgt ggtccagctt atttaggagg gaaacgattt
     1621 gtcaccagca caaagaagaa ttttactgta tatcctttca tttatctttg tcatcggcgc
     1681 agtcgtctat tttgtcaaaa gcgattatct gtttacgctg attttcattg ccattgccat
     1741 tctgttcggg atgcgcgcgc ggaaggctga ctcgcgatga gcattttgga tatacacgat
     1801 gtatccgttt ggtatgaacg ggacaacgtc atcttagaac aagtagattt acatttagaa
     1861 aaaggcgccg tttacgggtt gcttggggta aacggcgccg gaaaaacgac actgattaat
     1921 acgctgacag gcgtgaaccg caatttcagc gggcgcttta cactgtgtgg aattgaagcg
     1981 gaggccggca tgccgcagaa aacatcagat cagctgaaga ctcaccgtta cttcgccgcc
     2041 gattatccgc tgctatttac agaaattacg gcgaaggact atgtgtcttt cgtccattcg
     2101 ctttatcaaa aggatttttc agagcagcag tttgccagtt tggccgaggc ctttcatttt
     2161 tcgaaataca tcaacaggag aatttcagag ctgtccttgg ggaacaggca aaaggttgta
     2221 ttgatgacag gcttattgct gcgcgctccc ctgtttattt tggatgagcc gctcgtcggt
     2281 ttggatgtgg aatcgataga ggtcttttat cagaaaatgc gcgagtactg tgaagcaggc
     2341 gggaccattt tgttttcttc tcatctgctc gatgtcgtgc aaagattttg tgattacgcg
     2401 gctattcttc acaacaaaca gatccaaaag gtcattccga ttggagagga gaccgatctg
     2461 cggcgggaat ttttcgaggt gatcggccat gaataacata atccccatca tgtctttgct
     2521 gttcaaacag ctttacagcc ggcaagggaa aaaggacgcc atccgcattg ccgcaggcct
     2581 tgtcattctg gccgtgtttg aaatcgggct gatccgccag gccggcattg atgaatcggt
     2641 gttgcgcaaa acgtatatca tactcgcgct tctcttaatg aacgcatata tggtgtttct
     2701 ttctgtgaca tctcaatgga aggaatctta tatgaaactg agctgcctgc tgccgatttc
     2761 ttcacggagc ttttggctcg cccagagtgt cgttttgttt gtcgatacct gtttgagaag
     2821 aactttattc ttttttattt taccgctgtt cttatttgga aacggaacgc tgtcaggggc
     2881 gcaaacattg ttttggctcg gcaggttttc gttttttacc gtttactcca ttattttcgg
     2941 agttgtgcta agcaactatt tcgccaaaaa gaagaactgg atgtttctgc tgcatgcggc
     3001 gatattcgcc tgtgtatgcc tcagcgccgc ttttatgccg gccgccacga ttccgctttg
     3061 cgcggttcat atcctgtggg cagtggtcat tgactttcct gtctttctgc aggcgcctcc
     3121 gcagcagagc aagatgcatt catttatgcg gcgatctgaa ttttcgtttt acaaaagaga
     3181 atggaaccga tttatctctt ctaaagcgat gctgttaaat tacgcggtca tggcggcgtt
     3241 cagcggcttc ttttcgttcc agatgatgaa taccggcatc ttcaatcagc aagtggttta
     3301 tatcgtgatt tccgcgcttt tgctcatctg ctcgccgatc gcccttttgt attcgattga
     3361 aaaaaatgac cggatgctgc ttatcacgct tccgatcaag cggaaaacga tgttttgggc
     3421 gaaatatcgc ttttattcag gcctattggc aggcggattt ctccttgtcg tgatgattgt
     3481 gggtttcatc agcggccgtc cgatttcagt tctcactttt ttgcagtgca ttgagttgct
     3541 gctggcggga gcttttatca ggttaactgc agatgaaaaa aggccctcct tcagctggca
     3601 gacggagcag cagctatgga gcggtttctc aaaatatcgg tcttatctgt tttgtcttcc
     3661 cctattctta gccacattag ccggcaccgc tgtatccttg gcggtcattc cgatagccgg
     3721 tctggtcata gtctattacc tgcaaaaaca ggatggtggt ttctttgata caagcaaaag
     3781 agaacggctt ggaagttaac ctgctgaaga ctcatcaatt ttcaactatt tcaatcgccg
     3841 cgagctttct gaaaccgatc gaaagcgcgg cggaacctga ggaagaaacg atttattttt
     3901 acggcgccgc cgcatacctg aaggagcaaa tcattgacgc ttttggttat gctgccggca
     3961 gccgtttcat gtactcagcg aatctctttt ttgatcagca gctgaaaacc tgcgggaccc
     4021 gtttgattca cccattatat aacgggaatc ttcatgttga cgccctgatg aaaacttttg
     4081 cagacttgtc tttcccttct tctctttcat tcgaagcatt tgaaaaggcc aggaatgagc
     4141 tgctgctgaa aatcgaaaag aaattcactg atcccttctc ctactcggcg gctcgcttgg
     4201 ctgaggaggt cttcggaaac ccgatgtacg gcacaggcat gtttggccgg aaagacagga
     4261 tagaggcgat tcatcctaaa cggtttctcg acgcaacgga ctttatcgtt gatttagtgt
     4321 cccagcaaaa acagctgaac atattgggac aagtacaagc atgtgatgtt cggggacatg
     4381 ccccgcaaac gtccgctgta acgtccggaa gaatacccgt aaaccggcat gtttttgaaa
     4441 cagagacacg cagcgctgca ggtccttccg tcttgacact cggatttgac tgcggagaga
     4501 tgaaagatgc cagcgattat atcaaaatac agctaataga cggattactg ggaaagtacg
     4561 gccattccgc tttattcaag cacttcagag agaaggatct ggcagtctat cacgttatca
     4621 cccgttacga tgtcatgaac aatttgctgc ttgtttcaat atgtacagat cagcttcatg
     4681 agatagacat tcccccgcgc gttttggaag ctgtctcagc ttttcataca gatgagcggg
     4741 aactagaaca ggcaaagcag tttttacgca atgaattgct gctgcaattc gattctcccg
     4801 aaggtctatt ggcctatatg gggatcctgc gccgcttctc ctgcacgaaa gaagccttgc
     4861 tggatggcat ctcagcggtt acatgccgtg atgtattgca attcatagcg accatcaatt
     4921 atatcggagc tcatgtagta aggggatgaa gagatggaaa agaaagcctt ttttcaacaa
     4981 ctggatgaac gaaccgatat cagatacaca gacagcggac taaaaatatt cagattgaaa
     5041 ttcccccgcg cccacctgcg gctgtgcaat gtaaaaatcg attttggaag ccgggatgta
     5101 tgtatacggg cagaatccgg tgatacactg cttccgtatg gcacagcgca ttttttagag
     5161 catcttctct tctggcataa cggccgcaat ctgtacagtg atttttttgc gcatggcgcg
     5221 cttttaaacg cattcactac ctacaccgat accaatttca tgtttacctc attaccggat
     5281 cggctcagac aaacgatccc catcctgctt gatgctttat ggaaccactc atttgacaag
     5341 aagattgtcg ctcaggaaaa agctgtgatt acaagcgaaa ttcaaacagc acaccttaac
     5401 catcagctct catatcatta tcagctgatc agcatgcttt ctccctcctc accagctgcc
     5461 gttttccccg caggcagaat cgaagatatt gaggcgctgg acatcagtga tttacaaaaa
     5521 gcctataagg ctgcctacca agcccatcgg atgacgctgt ttttgattgg gggctcagaa
     5581 aatacagaaa cgcttttgcc tcctcacctc cagctggaaa agcgtccgga ttatcatgct
     5641 gaaagaaaaa tcatcccggc atgccctcca gccctctcac aaaaaatggt gctgggtgat
     5701 gaggagcgga tggaagatac atggaccgga ttacagatcg gcgcacttcc cgggcaaaac
     5761 gatctgttgg cgataaagct ttattgggat atcgcggctc gtattctatt tcaattagat
     5821 tcaccgtttt ttcaagagat tcagcaaacg taccgcctag aaatcgatcg tttgtcagcc
     5881 gagacctata tctatgagga tggcggtttc ttgatccttc acagtcaagg gacccattct
     5941 tcagcttata tcgatgtggc ttcatactat gtcacacaga agaaagaaca ggttgccgcc
     6001 tggcttcaat acggcaagga ctctttgaca gacgcgatca tttatgacag cgattatgtg
     6061 cgtaaatgct tcgagtgggc agccgagtgt gacaggtgcg attgctcgtt tcttgacatg
     6121 taccacatca ttcaagatat ggatgcgcag gttttcttgt ctctcattga tgcaatggca
     6181 tcttctaaca aagcgatcat tcacatttct cagaaagagg cgatcagaca atgaaaaaaa
     6241 acactgtctt taccctttta ttgctgctta taggtatggc ggcttattcc ttcggctggg
     6301 ttcaggccgt tgccgaagcc gccgcccaat atgtacagat gatcaacaat gatgctgtgc
     6361 ggctcgggct gctggcttgt accgctgccc tcctgatgct gcctgctttt ctctatcttc
     6421 attatgtcac ccaatccgtg aaaaacatga cagcagcttt tcagaaactc acacagtctc
     6481 atcaaagctg ctgtgacttt cagcaacaca acttgtgcag ccgatatgca gaagacgtca
     6541 aatcgctgcg tgacagctat aaaaacgtcc gccaaacata cgtgatggct gccgtgttgt
     6601 gccaagtcat catattcggc tgcatgttcg aaatcgttaa agccgtccct ttccgccttc
     6661 acacgccccc tgccctttca atgggacttg cgatgctact gattctgtat ttattgtttt
     6721 gcatgcgaac atatttgcgg cagcttttcc ggcacggcag cctgttcaga aaagtgtttg
     6781 cgggagcgct ggcagcagcc gggatttggt ggatgctcag tttctctata agtgaactgc
     6841 tgtttctgat tatcctggct accattcagc aaatcggatc atttatttat aaacgattct
     6901 cttatcgcag caccgcttct cttgatctat aaaatagcta catcgcaatc gcagacggac
     6961 ccgcgccaac cggaatcacc gtcacggctg tataatcact tgtgcggtac acggtcacag
     7021 cattgtcgtt gggctgtgcc gcataaatat actgtttgtc cggcgttacg gcgaggtcaa
     7081 aagcgccggg gagagacacg tttgcaatga tcctctgtct ggccgtatta actacatata
     7141 agttattaat aagaaacggt tcactatatg gctctagaaa ataagctcta gtgctatcga
     7201 gagaaaatac aatcgtcctc agcgtttcaa ataaacggct gaagtcccct cccctgctta
     7261 atggagacaa actaatctcc gttacacctt tcggccacag ctcaccattc aacacgtacg
     7321 caaaatttcc agcgtaagga gttgcaatta aactgggaaa ttcaaatgaa tctatgatac
     7381 tttctaccaa ctgcccagta tttgcatcat atttatcaac cgaccaactg cttccattag
     7441 cggtatagac atactgtcca ttcggatcaa gagcaaagtc taaagcgccg ggtatcggaa
     7501 tgacatcaat gaccgattga gaggccgtgt taatcacata tatagatccg gcggccatca
     7561 cgtatgcgaa ctcatctgtt ggatcaaatt cgatctttct cggccctcct ccaacagtaa
     7621 tggtatttat gatggttaat gttttattat caatcactga gacaaggttg gtatttccat
     7681 ggaggacata cgtgaatgct ttatcgaaag taacgcctag attagttggc acgtcagaaa
     7741 aagggattgt ttttacaaca gtgtttaaat ctgcatcaat aaccgaaacc gtgctgtctc
     7801 cagtattggc agtaaacaca tacgattgag ggtctggtga tggcggtaaa acaagtgtcc
     7861 cggtcaccgt aagcggactg ccgtagaaag gcggtacaat gagcagatct tccactgtca
     7921 tttgactaaa atcaggacag cggtcagact gtgctgcata ataaacaact tgatcaatct
     7981 cttcagtatg aatcacagaa accgccccat tgccttgtcc atattgattt cgtacaggcg
     8041 acacactgac aagaagcgta atggtccctt gtactctcac agcatatcga acaccgatat
     8101 cttctggttc cggcccagtc tggattaagc aaggctcact gatacaggac acattgtctg
     8161 tactccatgt aacagccgct gacgcttcgg ccgaatcaac cttgaagccc tcagggatat
     8221 ctatcggcac ttgaaacggc gcttctcggc taatttcctc atcacaaaaa cagaaacaat
     8281 tttcctgtaa agcagaaaga tcattctttt tcatgatttc acgtcctttt agaaatgcac
     8341 aacatatagt tgattaaatc gcaatagctc ccggtgaaac cccaagagat atgacagtct
     8401 ccacggagta atcatccgtg ttgtaaacag tgatgctctg ttctagaaca tgagttgcat
     8461 acagaaactc gccattcggg gtaaacgcaa agtctcttgc cgactgcgga acatttccta
     8521 taacgcctgc tccatttgga ctgacagaat ataaattgcc agtgaagccg tcatataaat
     8581 acacctctgc tccactcgta aacattcgat attccccttc atactccagc tcttgggtgc
     8641 tgctgatggt aaacgtattt aaatcaataa ccgtcaaata attaaaaaag aattcttgtt
     8701 ctaatacata ggcataccgc tccggccaat ttgtttctat ggttgatacg ataagctctc
     8761 gttcaattgt tcctgtgact tcaccggtag ttaggtccac tttttgcact attccaaaat
     8821 tcagaacata ggcgaataac ccattgggat cgattgcaac atcatatcct tccacaggaa
     8881 tcgacctatc cacagttaac gtatcaattc caatcacata aaccgcagta ccggtgaaaa
     8941 cataagcaaa ctcatgatta gggataaatc taatcaatcg aggcggctga tccagcaata
     9001 tagttgctgt cactgttaat gtgtcataat cgatgacaga aatcacatta ttgttgggat
     9061 gtaagacaaa cacagcgctt ttatctggcg taatttcaat acctgccgga ttgtacggaa
     9121 gagcaatcgt tgtcacaaca gtatgggtgt ttgtatcaat cacagaaact gattgatcat
     9181 ttggattcgc tgtaaacgcg tagacgggtt ccggctccgg tacaagcaca atcgtccccg
     9241 tcaccgataa aggactgccg taaaacggcg gaacaacaac aaggttctca atcgtgatgt
     9301 cactgatatc cgggcaatca tccggttcat cggaataata gacgacttga tcgatttctg
     9361 cattgtgaat gacggaaaca gccccgtccc cttgtccata ttgatttcgc acaggtgaga
     9421 cactgacgag tagcgtaacg gttccctgca ggcgcactgc aaattgaaca ccgacctcat
     9481 caggctctgg ccccgtttga attaagcaac ggtcactgac acaagaaagg ctgtctgcat
     9541 tccacgtcac gtttgcaaca gcttcagccg gatcaacgac aaatccttca ggtaattcaa
     9601 tcggcgcttg aaacatggct tctcggcttg cttctccctc acaaaaacat aagcactctt
     9661 cttgttctgc tcctgctttt tctttaaagg aaagcttgtt ttttctcatt ccttcacttc
     9721 cttttcagac atacactgct cacgcagata taacagaata tggaagtgta acgtgcttgc
     9781 ttgtacaaat tgctgagggt aaacgcttct ttttgaaaat atatctccaa acatgcggtg
     9841 taacgaaaga aaaaattgcg gtttttttgc gcttctcaca agaatgttga tgataaaata
     9901 tgacatatat agaattatga agggagggat ttgcaaacgt gacaggtgtc atatcttctt
     9961 cttccatcgg agaaaagatt aacgaatggt atatgtacat acgccgattc agcatacccg
    10021 atgcagaata tttgcgacga gaaatcaagc aagagctgga tcaaatggaa gaagatcaag
    10081 accttcattt gtactattca ctgatggagt ttcggcacaa cctaatgctt gagtaccttg
    10141 aaccgttaga aaaaatgagg attgaggaac agccgagact gtctgatctg ctgcttgaga
    10201 ttgataaaaa acaggctcgt ttaactggtc tgcttgagta ctattttaat ttcttcagag
    10261 gcatgtatga gctggatcag cgggaatatc tgtcggctat taaatttttc aaaaaggccg
    10321 aaagcaagct gatattcgtt aaggatcgga tagagaaagc tgagtttttc tttaagatgt
    10381 ctgaatctta ttactatatg aaacaaacgt atttttcaat ggactatgca cggcaagcat
    10441 atgaaatata caaagaaaat gaagcttata atataagatt gctgcagtgt cattctttat
    10501 ttgccaccaa ttttttagat ttaaaacagt atgaggatgc cgtctcacat tttcaaaaag
    10561 cttattctat ggcagaagct gaaaagcagc cccaattaat gggaagaact ttgtacaata
    10621 tcgggctttg taaaaacagc caaagccaat atgaggatgc cataacatat ttcaaaagag
    10681 caatagctgt ttttgaagaa tcaaatattc ttccttcctt acctcaagcg tattttttaa
    10741 ttacacagat ccattataaa ttaggaaaaa tggataaagc tcatgaatat catagtaagg
    10801 gaatggctta ttcacaaaag gccggagatg taatatattt atcagagttt gaatttttga
    10861 aatctttata cttatcaggc ccggatgaag aagcaattca aggatttttt gattttctcg
    10921 aaagtaaaat gttgtatgct gatcttgaag atttcgctat agatgtggca aaatattatc
    10981 atgaacgtaa aaattttcaa aaagcttctg cttatttttt gaaggtggaa caagtaaggc
    11041 aacttattca aggaggagtg agtttgtatg aaattgaagt ctaaactatt actctcttgt
    11101 ctggctctaa gcactgtgtt cgtggcaaca actattgcaa atgcacctac acaccaaatt
    11161 gaagttgcac aacgaggaat gatttaaccg ccgtccatcg gcggtttttt ttgtcccctc
    11221 tttacccaat ctcccaattc atgctatgat tttttttcaa taatcttgaa gagagtggaa
    11281 atgcagcatg tctctgtaaa gtgtgagaac ccactttaca cagtggaatc gagaaaatga
    11341 tgtgacggag ttcgaaacgt cgagtgcgac agttgaacag gcagctgaga cgatcggcgt
    11401 aaacccggct agaatcgcca agtccctgtc cttcagaggg gaaggatatc aggcgattct
    11461 gattgtggca gccggcgatg ccaagatcga caacaaaacg ttcaggcaaa catttggctt
    11521 taaagcaaga atgctctctc ctaatgaggt actggagcag acaggccatg aaattggagg
    11581 agtttgcccc tttggtttgg cttatg
//
