LOCUS       c00073_gnlPro..        15270 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMHBEFPG_83.
ACCESSION   c00073_gnlPro..
VERSION     c00073_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 11:35:31
            Original ID  :: gnl|Prokka|MMHBEFPG_83
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15270
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15270
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2745:5270]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2746..5270
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15270
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15270
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..164
                     /locus_tag="ctg73_1"
                     /transl_table=11
                     /translation="EEKEKREEKEKRGERINAEHFASKFEVNYSVETISTSIFEVIHEV
                     ISAFNRKF"
     CDS             130..282
                     /locus_tag="ctg73_2"
                     /transl_table=11
                     /translation="MRLFLHSTANFEVKHSGFFTQILERKSKKILYLDDTKKEIALHYK
                     RGNYN"
     CDS             279..1316
                     /locus_tag="ctg73_3"
                     /transl_table=11
                     /translation="LKKWLLGIGALTLSFSLAACSSDSSSSNEKSSSSKTSSLSAEDQF
                     KKDAKSYAYEKVNSAGIKKGTKIVIEGDVTYADNVNDDGDTVSKNVEFTVSKNSDGSEV
                     YTVSNKSADKFKLNDTVKIYGTYEGRAEGSALPKVKAVYVEKIDKEKEQAKQDAALKEQ
                     FEKTGEGDIEGLGHVKDIGVGYNDEVGIDGKDTPIKPVTMGSMKLYINSVDVLEIQPDD
                     DAKSLYFNDQDKVRAIVVDMKAENTSSKDVTFDPNQAVIVTNTGEQLESEMGLMGEVGG
                     DFLGKVKKEGQAWWILKDNSKDITSLKMIISPPSDAKTYDDLGSEKRLDFDILSFEEAK
                     KKDSN"
     CDS             1456..1932
                     /locus_tag="ctg73_4"
                     /transl_table=11
                     /translation="LRYTNSHLEDWIEQLYREINITKPHEINFDRIAQALDILIVYNPE
                     TSFALRFNGMYTISLDSRKTRQEQWLDFAHEVCHDFRHMNDDKIMPASWKRYLEYQANY
                     FAYHFCIPTFMLRAMDIPRNLYDAVQVIADAFKVPESFAMTRINMYFNKKRLII"
     CDS             complement(1944..2126)
                     /locus_tag="ctg73_5"
                     /transl_table=11
                     /translation="LKEKEFQSKPLLTKREREVFELLVQDKTTKEIASELFISEKTVRN
                     HISNGMHTGRKLRAL"
     CDS             complement(2242..2589)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_6"
                     /sec_met_domain="HBT (E-value: 1.8e-14, bitscore: 46.9,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2.6e-08, bitscore: 27.4,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFGHMNNVTPFIYFEEARISYFKKLNMMSENKQTMTVVASQQCDY
                     LRQVMPYEELRIYVKTSAVGSSSLTLHYLGENLEGEPCFTGAVVMVQVSKESGKAVSWT
                     DEEKETLLHTR"
     CDS             complement(2746..3507)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 96.2; E-value: 3.7e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_7"
                     /sec_met_domain="Fer2_3 (E-value: 7.3e-30, bitscore: 96.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.5e-11, bitscore: 36.9,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00049, bitscore: 13.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQKTIRFIITRQDTADSTPYDEEFEIPYRPNLNVISALMEIRR
                     NPVNVKGEKTTPVTWDMNCLEEVCGACSMVINGKPRQSCTALIDQLEQPIRLKPMKTFP
                     VVRDLQVDRSRMFDSLKKVKAWIPIDGTYDLGPGPRMPEKRRQWAYELSKCMTCGVCLE
                     ACPNVNSKSKFMGPAPMSQVRLFNAHPTGAMNKSERLEALMDEGGLADCGNSQNCVQSC
                     PKGIPLTTSIAALNRDTNLQAFRNFFGSDRV"
     CDS             complement(3510..5270)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 296; E-value:
                     1.7e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_8"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.4e-90, bitscore:
                     296.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.7e-43,
                     bitscore: 138.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCA
                     QGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFN
                     RTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGA
                     VLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQ
                     QGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGN
                     LVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDP
                     RKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGG
                     MVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEW
                     MTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARV
                     ITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRK
                     RDYSKKKVAK"
     CDS             complement(5304..5912)
                     /locus_tag="ctg73_9"
                     /transl_table=11
                     /translation="MSGNREFYFRRLHSLLGVIPVGIFLIQHLVVNQFAARGAEAFNSA
                     AHFMDSLPFRYALEIFIIFLPLIYHAVYGVYIAFTAKNNAGQYSYMRNWLFVLQRVTGI
                     ITLIFVSWHVWETRIAAQMGAEVNFDMMANILSSPAMLGFYIVGVLSTIFHFSNGLWSF
                     AVTWGITVTPRSQRISTYVTLIIFVALSYVGLKAIFAFV"
     CDS             6205..6651
                     /locus_tag="ctg73_10"
                     /transl_table=11
                     /translation="MKSKFEASIDNLKEIEMNAYAYELIREIVLPDMLGQDYSSMMYWA
                     GKHLARKFPLESWEEFPAFFEEAGWGTLTNVSAKKQELEFELEGPIISNRLKHQKEPCF
                     QLEAGFIAEQIQLMNDQIAESYEQVKKRADKVVLTVKWDMKDPV"
     CDS             complement(6695..7921)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_11"
                     /sec_met_domain="AA_kinase (E-value: 2.3e-54, bitscore:
                     177.5, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGK
                     STDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALQEKGYDAVSYTGWQAGIRT
                     EAIHGNARITDIGTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAA
                     LKADKCDIYTDVPGVFTTDPRYVKSARKLAGISYDEMLELANLGAGVLHPRAVEFAKNY
                     QVPLEVRSSTETEAGTLIEEESSMEQNSIVRGIAFEDQITRVTIYGLTNGLTTLSTIFT
                     TLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVLEEYKDALEFEKIETESKLAK
                     VSIVGSGMVSNPGVAAEMFAVLAQKNILIKMVSTSEIKVSTVVSENDMVKAVESLHDAF
                     ELSKHPSAV"
     CDS             complement(8291..10063)
                     /locus_tag="ctg73_12"
                     /transl_table=11
                     /translation="MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYF
                     TGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMNLIKKHDPKYNVMLKDDKTYPFIKL
                     THERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCLYYH
                     LGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELR
                     DQIAHIESTMEKQKMTMNDLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQ
                     EADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQLLETNVHQPKKGPKKELLMLA
                     HKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMI
                     VFIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQ
                     INAARDVIENELGLDIPIAGLAKDEKHRTSNLLIGEPLEVVYLERNSQEFYLLQRIQDE
                     VHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSVKKMKEASLEDIKKAGV
                     PTAAAQLLYDKLQK"
     CDS             complement(10199..10513)
                     /locus_tag="ctg73_13"
                     /transl_table=11
                     /translation="MAIVKATDQSFSAETSEGVVLADFWAPWCGPCKMIAPVLEELDQE
                     MGDKLKIVKIDVDENQETAGKYGVMSIPTLLVLKDGEVVETSVGFKPKEALQELVNKHL
                     "
     CDS             complement(10836..12344)
                     /locus_tag="ctg73_14"
                     /transl_table=11
                     /translation="MKGMIRGMSEHQAVIQTDIVKGTINKNIYGHFAEHLGRGIYEGIW
                     VGTDSDIPNINGIRKDVLEALKQLHIPVLRWPGGCFADEYHWANGVGDRKTMLNTHWGG
                     TIESNEFGTHEFMMLCELLECEPYICGNVGSGTVQEMSEWIEYMTFEEGTPMSDWRKQN
                     GREEPWKLKYFGVGNENWGCGGNMHPEYYADLYRRFQTYVRNYSGNDIYKIAGGANVDD
                     FNWTDVLMKKAAGLMDGLSLHYYTIPGDFWKGKGSATEFTEDEWFITMKKAKYIDELIQ
                     KHGTIMDRYDPEQRVGLIIDEWGTWFDPEPGTNPGFLYQQNTIRDALVAASHFHIFHQH
                     CRRVQMANIAQTVNVLQAMILTEGERMLLTPTYHVFNMFKVHQDASLLATETMSADYEW
                     NGETLPQISISASKQAEGDINITICNIDHQNKAEAEIELRGLHKAADHSGVILTAEKMN
                     AHNTFDDPHHVKPESFRQYTLSKNKLKVKLPPMSVVLLTLRADS"
     CDS             complement(12541..13518)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 153.1;
                     E-value: 2.6e-47)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg73_15"
                     /sec_met_domain="ETF (E-value: 5.2e-47, bitscore: 153.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 4.6e-38, bitscore:
                     122.2, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKKVIVLGEIRDGELRNVTFEAIAAGRTISGDGEVIGVLIGENV
                     QNIAQELIHYGADKVLTAEDPKLKTYTADGYSQIMRGVIEQENPDSVIFGHTAMGKDLS
                     PKLAARLQTGLISDAIDVSVTGGNVVFTRPIYSGKAFERVISTDPMIFATIRPNNIQAS
                     EKDTSRSGSIESIDVSLTDLRTVIQEVVKKTADGVDLSEAKIIVAGGRGVKSKEGFQPL
                     QELAEVLGAAVGASRGACDADYCDYALQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEADIFKIADYGIVGDLFEVVPLLTEEFKQLNIHS"
     CDS             complement(13554..14327)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 160.1;
                     E-value: 1.8e-49)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg73_16"
                     /sec_met_domain="ETF (E-value: 3.6e-49, bitscore: 160.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLFVLMKRTFDTEEKIVIETGKIQDDGAEWIINPYDEYAIEEAI
                     QLKEKHGGTITAVTVGGEEAEKELRTALAMGCDQAVLINIEDDLEEPDQYSISQVLYHY
                     MKDQEFDLILGGNVAIDGGSGQVAPRLAELLDIPCITTITKLEINGTDAEAERDVEGDV
                     EKIKTTLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLDEEDAEPKLKTIE
                     RFLPPKKEAGKLLQGEPAEQAKELVSLLRSEAKVI"
     CDS             complement(14342..15118)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_17"
                     /sec_met_domain="ECH_1 (E-value: 3.2e-66, bitscore: 216.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDAG
                     VRSIIIHGEGRFFSAGADIKEFTSLKGNEDSSLLAERGQQLMERIESFPKPIIAAIHGA
                     ALGGGLELAMACHIRIAAEDAKLGLPELNLGIIPGFAGTQRLPRYVGTAKALELIGSGE
                     PISGKEALDLGLVSIGAKDEAEVIEKAKALAAKFAEKSPQTLASLLELLYSNKVYSYEG
                     SLKLEAKRFGEAFESEDAKEGIQAFLEKRKPQFKGE"
ORIGIN
        1 aagaagaaaa agaaaaaaga gaagaaaagg agaagagagg agaaaggatt aatgctgaac
       61 acttcgcctc aaaatttgag gtaaactatt cagttgaaac catttcaacc tcaatttttg
      121 aggtgatcca tgaggttatt tctgcattca accgcaaatt ttgaggtaaa acattcaggg
      181 tttttcactc agattttaga gagaaaaagt aaaaaaatcc tttatttaga cgatacaaag
      241 aaagagattg cacttcatta taaaagggga aattacaatt gaaaaaatgg ttattaggta
      301 ttggagcatt gactcttagt ttttctttag ctgcatgtag ttctgactct tcaagtagta
      361 atgaaaaatc ttcttcaagc aagacaagct cacttagtgc tgaggaccag tttaaaaaag
      421 atgcaaaatc atatgcctat gaaaaagtaa atagcgccgg cattaagaaa gggacaaaaa
      481 ttgtcattga aggcgatgtt acttatgcag ataacgtcaa tgatgatggg gatacagttt
      541 ctaaaaatgt tgagtttact gtaagtaaaa atagcgatgg atctgaagtt tacacagtaa
      601 gcaataaaag cgctgataag ttcaaactaa acgatacggt taaaatttat ggtacatatg
      661 aaggcagagc tgaaggaagt gcccttccta aagtgaaagc cgtttacgtt gaaaaaattg
      721 ataaagaaaa agagcaagct aaacaagatg ctgcactaaa agaacagttt gaaaaaactg
      781 gcgaaggtga tattgaagga ctgggccacg ttaaagatat cggcgttgga tataacgacg
      841 aagtcggaat tgacggtaaa gacactccta taaaacctgt tacgatgggc agcatgaagc
      901 tttatattaa cagtgtcgac gttctcgaaa ttcaaccaga tgatgatgca aaatcacttt
      961 attttaatga tcaagataag gttcgggcta ttgttgtcga tatgaaggcc gaaaacactt
     1021 cttctaagga cgtaacgttt gaccctaacc aagctgttat tgttacaaat acaggagaac
     1081 agcttgaatc tgaaatggga ttaatgggtg aagtaggcgg agacttctta ggaaaagtta
     1141 aaaaagaagg ccaggcatgg tggatactta aagataattc aaaagatatc actagtttga
     1201 aaatgattat ttctcctcca agtgatgcaa aaacctatga tgatttagga agcgagaaaa
     1261 gactagattt tgatatcttg agttttgaag aagctaagaa aaaagattca aattaaattg
     1321 agcccctaaa gggggctttt cttttcgcta aaaaaaggaa catatgtttg ttcaccttcg
     1381 acaaaatagg tgataagata caataaagcc catgataaaa gtcacatatt tggttattta
     1441 agggaggttt catctttgag atacactaac agccatttag aagattggat tgaacagctt
     1501 tacagggaga tcaatattac aaagccacat gagattaatt ttgatagaat tgctcaggcc
     1561 ttggacattt taattgttta caatccggaa acgagttttg ctctgcgatt caacggcatg
     1621 tatacaattt ctttagattc acgaaagaca cgacaggaac agtggctgga ttttgctcat
     1681 gaggtttgcc atgattttag acacatgaac gatgataaga tcatgcctgc ttcgtggaaa
     1741 cgatatttag agtaccaggc caattatttt gcgtatcact tttgtatacc tactttcatg
     1801 ctccgagcaa tggacatccc ccgtaatcta tacgacgcag ttcaagtcat tgccgatgcc
     1861 ttcaaggttc cagagtcatt tgcgatgacc cgcatcaata tgtacttcaa taaaaaacga
     1921 ctcatcatat aaaaaaagag cctctaaagg gctcttagtt tgcgaccggt atgcatacca
     1981 tttgaaatat ggtttcgaac ggttttctca ctgataaata gctcgcttgc aatctccttt
     2041 gttgtcttat cttgaacgag caattcgaac acttctcttt ctcttttcgt tagcagcggc
     2101 ttcgattgaa attctttctc cttcaagtat tgtaaccctc cttgctaagg tgagagcgaa
     2161 tcagaaacga atgggttttg atatagtcga gatatcatat gtaagaaggg cgcaggaggt
     2221 gacgtttaca agataattag tttatcgtgt atgaagaagc gtttctttct cctcatccgt
     2281 ccagctgaca gccttgccgc tttcctttga gacttgaacc atcacgactg ccccggtgaa
     2341 gcagggttcg ccttcgaggt tctctccgag atagtgcaag gtaagagatg aactgccgac
     2401 tgcgcttgtt ttcacataga tgcgcaactc ttcataaggc atgacttggc gcaaataatc
     2461 gcattgctgg cttgccacga ctgtcatggt ctgtttgttt tcactcatca tattcagctt
     2521 tttaaaataa gaaatccgcg cctcctcaaa atatataaaa ggggttacat tattcatatg
     2581 cccaaacatg tctgtctccg aaaatcttac ggatacctca ttgaaaaaag aaaaggatgt
     2641 tttccattct tgaaacggca tatcaatata agcgggaagc ttcacctttt ttcatctcct
     2701 tattgtttaa aaaaacctct cccatgcgga agaggttttt tcttcttata ctctgtcgct
     2761 tccgaagaaa ttgcggaacg cttgtaagtt tgtatctcta ttcaaggctg caatcgaagt
     2821 ggtaagcgga atccccttcg gacaggattg aacacagttt tgcgagttgc cgcaatctgc
     2881 aaggccgcct tcatccatta atgcttctaa tcgttcagat ttattcatgg cgcctgtcgg
     2941 atgcgcgtta aacaggcgga cttgcgacat cggtgcaggc cccatgaact tcgatttgct
     3001 gttcacattc gggcaagctt cgaggcagac gccgcatgtc atgcattttg ataattcata
     3061 tgcccattga cggcgttttt ccggcattct cggccccggt cctaaatcgt acgtaccgtc
     3121 aatcggtatc catgctttaa cttttttcaa tgaatcaaac attctgctgc gatcaacctg
     3181 caaatcacga acgactggga atgttttcat tggttttaaa cggatcggct gttcaagctg
     3241 gtcaataagc gccgtacaag actggcgggg ctttccgttt atgaccattg aacatgcgcc
     3301 gcatacttcc tcaaggcagt tcatatccca tgtgacaggg gttgtcttct cacctttgac
     3361 attaaccgga ttccggcgga tttccatcag agcggaaatg acgttcagat tcgggcggta
     3421 tggaatctca aattcttcat cataaggcgt gctgtcagct gtatcttgac gtgtgataat
     3481 aaatcgtatg gttttttgtt cactcatgat tatttcgcca ccttcttctt cgagtaatcc
     3541 cgtttccgag gcgttatcag tgatacatcg acatcctgat actcaaattc cggcgcttca
     3601 tacgggctta catgtttagc cattgttgtt ttgagccatt catcatcatt acgttcagga
     3661 taatccggtt tataatgggc cccccggctt tcattacggt tgtatgcgcc aagggtaatc
     3721 accctcgcaa gctgaagcat gtttgagaac tggcgtgtga acatcgctcc ctggttgctc
     3781 cattttgtcg tgtcattgat gttgatcttt ttgaagcgct ccattaactc ctgaattttg
     3841 tcatccgttt tcaaaagctt gtcattatgg cggacaaccg ttacgttcgc cgtcatccac
     3901 tcaccgagct ctttgtgaag aacataggca ttttcggttc cgtccatact cataatatca
     3961 gcccattttt cttcttcttt cttaacgtga gcgtcgaata aagatgaaga catgtcttcc
     4021 gctgaagatt ctaagccgtt tacatatttc acagcattcg gaccggccac catgcctccg
     4081 taaatcgcag acagcaggga gttcgctccc aagcggttgc cgccgtgcat agaataatca
     4141 cattccccag ccgcaaacag tccagggata tttgtcattt gatcgtaatc cacccataaa
     4201 ccgcccatag aataatggac cgccgggaag attttcattg gaagcttacg cgggtcgtct
     4261 cccatgaatt tctcataaat ctcaatgatg ccgccaagct taatatcaag ctctttcgga
     4321 tctttatgag acagatcgag atataccatg ttttcaccgt taatgccgag cttctggttc
     4381 acacacacat caaatatttc gcgtgtcgca atatcacgcg gcaccaggtt tccgtatgcc
     4441 ggatattttt cctccaggaa ataccatggt ttgccgtctt tatatgtcca cacgcgcccg
     4501 ccttcaccac gcgctgattc actcatcagt cttagtttgt catcgcccgg tatggctgtc
     4561 gggtggattt gaatgaattc tccgtttgca taatacgctc cctgctgata aacgattgat
     4621 gcagcagatc ctgtattaat catggagttc gttgattttc caaagatgat tcccggtccg
     4681 cccgtcgcca taatgacagc gtctgaacgg aaggattcaa tttgcatgtt tgtcaggttt
     4741 tgtgcaacaa ttccacggca ggttctgtca tcatctaaaa cagcgccaag gaattcccag
     4801 ccttcgtatt ttgtgaccag acccgcaact tcgtatctgc gcacttgctc gtccagtgcg
     4861 taaagcagct gctgtcccgt cgtcgcacca gcataagcag ttctgtggtg ctgtgtaccc
     4921 ccgaatcggc ggaaatcaag caggccttca ggcgtccggt taaacatgac gcccatccgg
     4981 tctaataagt ggatgatcga aggcgccgct tcacacatcg ccttgaccgg cggctggttg
     5041 gcaagaaagt ctcccccgta taccgtgtca tcaaaatgtt cccacggaga gtcaccttcc
     5101 ccttttgtat tgaccgctcc gtttatgccg ccttgcgcac aaactgaatg agaacgtttg
     5161 acaggaacga tggaaaacaa tttaaccgcc attcctgatt ccgctgcttt aattgtcgcc
     5221 atgaggccgg caagaccccc gccgactacg ataatgcttg attgactcat gatagcccct
     5281 ctccctctag taatctagta ctcttaaaca aatgcaaaaa tcgcttttaa gcctacgtat
     5341 gacagtgcaa caaaaataat cagcgtaacg tatgtcgaaa ttctttgaga acgaggcgtt
     5401 accgtgatgc cccatgtaac agcgaaagac cataaaccgt tcgagaagtg gaaaattgtt
     5461 gataaaacac cgacaatgta aaaaccaagc atagccggag agctcaaaat attcgccatc
     5521 atgtcgaaat tgacctcagc acccatttgt gcggcaatgc gggtttccca cacgtgccag
     5581 ctgacgaaaa tgagggtgat gataccggtt acacgctgca ggacgaatag ccagtttctc
     5641 atgtagctgt attgacctgc gttatttttc gcagtaaacg ctatgtacac accataaact
     5701 gcatgataaa ttaatggtaa gaagataata aaaatttcca aggcatacct gaaaggcagg
     5761 ctatccataa aatgagcagc gctattgaat gcttcagcgc cccttgcggc aaactggttg
     5821 acgactaaat gctgaataag aaagatgccg accggtatga cgccaagcaa ggaatgcaat
     5881 cttcgaaaat aaaactctct gttcccagac attactttac cccctgtttg ataagtgcga
     5941 aatgtgctaa atctcttccc ccacttcttt caattgtaag cactttatta agatttattg
     6001 acaatttcat tttactcctc cctcaaaagg gcgtcaagaa aacgcgtaca taaattataa
     6061 ttttccgaat tgattagttg attgaaaaat tttattttat caatatatat ttcttgctta
     6121 atttttcata agaattacag gatcattctg taatcctccc ccctgtttga gctataatat
     6181 acgcaggaga gaggggagac agatatgaag tctaaatttg aagcatctat tgacaaccta
     6241 aaagaaattg aaatgaacgc ctatgcctac gaactaatac gagagatcgt tctcccagat
     6301 atgcttggcc aagattactc ttccatgatg tattgggcag gaaaacatct cgcccgtaag
     6361 tttcctcttg aatcatggga ggaatttccg gccttctttg aagaagcggg ctggggaacc
     6421 ctcaccaacg taagcgctaa aaaacaggag cttgaatttg aacttgaagg gccgatcatt
     6481 tccaaccggc ttaaacatca gaaagaacct tgctttcagc tggaggctgg ttttatcgct
     6541 gaacaaattc aattgatgaa tgatcagatt gccgaatcat atgaacaagt gaaaaagaga
     6601 gccgataaag tggttctgac tgtgaaatgg gatatgaaag acccagtgta atcaaaaagg
     6661 cggtgactgc atagtcccgc ctttttgatt gtcattacac agctgaaggg tgttttgaaa
     6721 gctcaaatgc atcgtgaagc gactcgactg ctttcaccat gtcattttcg cttacgactg
     6781 ttgacacttt gatttcagaa gtgctgacca ttttgattaa aatgtttttt tgcgctagta
     6841 cagcaaacat ttcagccgct acaccaggat ttgagaccat gccggatcca acaatggata
     6901 ctttagccaa tttgctttct gtctcgattt tctcaaattc cagcgcgtct ttatactctt
     6961 caagcaccgc aacggtttgg tctgcatctt ctgttttgac agagaaggaa attccagtct
     7021 tgtcctcggc ctgcgtttgg ataatgatat ccacgtttat gtttcttttg gcaagtgtcg
     7081 taaaaatagt agacaaagtt gtcaggccgt tagtcagccc gtaaatggtt actcttgtga
     7141 tttgatcttc aaatgcaatg cctctgacaa ttgaattctg ttccatggat gattcctcct
     7201 caattaatgt tcccgcttcg gtttctgtac ttgaacgcac ttctaacggc acttggtaat
     7261 ttttcgcgaa ctcaactgct cttggatgaa gaacgccggc gcctaaattg gcaagctcaa
     7321 gcatttcatc gtatgagatg cccgcaagtt ttctcgctga tttcacatag cgcggatcgg
     7381 ttgtaaacac gcctggcacg tctgtgtata tgtcacattt atcagctttt aaagcggcag
     7441 ccaaagcaac tgctgttgta tctgaaccgc cccggcccaa tgtcgtaatt tcacaatcct
     7501 ctgtcatgcc ttggaatcct gcaacaatga caatttttcc tttttcaagc tggtctgcta
     7561 aaaccgaagt gccgatatct gtaattctgg cgtttccgtg aatggcctcc gtacggattc
     7621 ccgcctgcca gccagtataa gacacagcgt catagccttt ttcctgcaat gccattgaaa
     7681 ggagtgaaat cgtgacctgc tcgcctgtcg ccagcagcat atccatttcg cgtttgctcg
     7741 gctggtcaga aatagctttt gcaaggctga ccaattcgtc agtggatttt cccattgctg
     7801 aaacgacgac aacgacttga tggcctttct gtttttctgc aattgcgcgg tttgccgcat
     7861 tttgaatttt ttcgactgag ccgacggaag tgcctccgaa tttttgtaca ataagaccca
     7921 tgtattacca ccctttacat tttggttcgt gcgggtgagg agaaagagcg ctttgtccac
     7981 aataaaaaaa gcaatgagag gaatactctc attgcttatc aattaatcat cataaatgat
     8041 tatgaacaac gagatagccc tccaagaaaa tgatttcttg acagccttac atttattcaa
     8101 tgcacggcca gcaaataata ccgatggggt tttacttgct tcggcgacgc tcccctttca
     8161 gcctttttca cagaatccat ctttctccaa aggcatactc ttgaagttcg cacctctatc
     8221 ttcaccatat aacacgatct aactatgaaa ttagttcaca ttttatcaga tcttatttaa
     8281 aaggacaaca ttatttttgc aatttgtcgt aaaggagctg agccgccgct gtgggaacac
     8341 cggctttttt gatgtcctca aggcttgctt ccttcatttt tttaacggaa ccgaaatgct
     8401 ttaacagcat tttctttctt ttctctccga tacccgggat gtcgtccaaa acggattgaa
     8461 acgcgctttt tccgcggatt tgcctgtgaa aactgattgc aaaacgatgc acctcgtctt
     8521 gaatgcgctg caggaggtaa aattcctggc tgtttcgttc cagatacact acctccagcg
     8581 gctcaccgat cagtaaattt gaggttctgt gtttttcatc tttcgctaaa ccggcgatcg
     8641 ggatatccaa gccgagttca ttttcaatga catcccttgc tgcgttgatc tgcccttttc
     8701 ctccgtcaat gataatcaga tcgggcagcg gcagattctc acgaagcact ctcgtatagc
     8761 gtcttctgac aacctctctc atagaaccgt aatcatccgg ccctgtaaca gttttgattt
     8821 tatatttgcg gtattccttt ttgtatggtt tgccatcgat aaacacaatc atcgcggaaa
     8881 ccgggtttgt cccctgtatg tttgagttat caaacgcttc aattctgtgc ggcgtataaa
     8941 tatttaatgc ctcacctagt ttctgcactg ccccgattga acgctcctcg tcccgttcga
     9001 ttaaagagaa tttttctttc aatgcgattt tcgcattttt atgggcaagc atgagcagtt
     9061 cttttttcgg gcctttcttc ggctggtgaa cgtttgtttc cagcagctgc tcgatcatgg
     9121 attgatctac gctgtccgga actaaaatct ccttcggaag gaagtggttg ttttttgaat
     9181 agaactgccc gatgaacgtg aggaactctt catctgcttc ctgataaagc gggaacatgc
     9241 tgacatcgcg ttcaatgagc ttcccttggc ggatgaaaaa gacctgcacg cacatccagc
     9301 ccttatcgta cgcgtacgcg aatacatcac ggtcgactag atcgttcatc gtcatttttt
     9361 gtttttccat cgttgattca atatgggcaa tttggtcacg aagctcttta gctcgttcaa
     9421 actcaagatt ctcagcagct tcatgcattt tctcttcaag ctcttttttg acctcattat
     9481 agccgcccct taagaaacgt gtaatgcttt caaccagctc tctgttcgtc tcttcggaaa
     9541 tatcctttac acacggagcg aggcattggc ccagatgata gtaaaggcac actctgtccg
     9601 ggagcttgga gcattttctg agaggataca gacggtcgag cagttttttt gtttcccttg
     9661 ctgcctgtac attcggatac ggcccgaaat agcgcccttt gtcttttttg acattgcgtg
     9721 tgacaatcag ccttgggtgg cgttcatggg tgagttttat gaaaggatag gttttgtcgt
     9781 ctttgagcat gacgttgtat ttcggatcat gctttttgat cagattcatt tctaaaataa
     9841 gcgcttcaag attggaggac gtcacgatat attcaaaatc ctcgatttcc gtcacaagcc
     9901 tttgggtttt cgcgtcgtga gaaccggtga agtaggagcg cactctgttt ttcagcactt
     9961 ttgctttccc tacgtagatc acagtctgct gccggtcctt catgagataa caacccggtt
    10021 gatcaggaag gagggcgagt ttttctttca gttgtttgtt catatgttac ccttccttat
    10081 gtttaatcct ttatttccag tttaacacga acgtttgttt ttctctatgg ttcacaattg
    10141 gcgaataaaa aaagcgatcc ctcaatcgga atcgctctgg catgtaagca gcggaaaatt
    10201 aaagatgttt gtttacaagc tcttgaagcg cttcttttgg tttgaagccg actgaagttt
    10261 caactacttc gccgtctttt aacacaagaa gagtcgggat gctcataacg ccgtattttc
    10321 cggcagtttc ttggttttcg tctacatcaa tttttacgat tttcagtttg tctcccattt
    10381 cttgatccaa ttcttcaaga acaggtgcaa tcattttaca aggtccgcac caaggagccc
    10441 agaagtctgc cagtacgacg ccttcgcttg tttcagctga gaaagattga tcagttgctt
    10501 ttacgatagc cattattgaa ttcctccaat gtgaaatgat gatttttagt atagcatctc
    10561 ccattcgttc acgctatttt aatgcttaca aattattttt tcctgatcac agccggttta
    10621 ctcattttta tatggttgaa tgggatatgc tcttttttta aaacacaaat ctgataatgg
    10681 ccccgatcac tacaattgcc ccaataatca ttaaaatggt acgaagcata agatcacatc
    10741 tcctcttcac tgtcatgtac tttaccatgc cctgccggag ctgttttaaa acctgaaaaa
    10801 gagcgccggc atgaagctcc ggcgctcttg cgcgattaag aatcagcacg cagcgtaagt
    10861 aagacgactg acattggcgg gagttttact ttcagtttgt ttttgctgag cgtgtattgt
    10921 ctgaaggatt ccggtttgac atgatgagga tcgtcaaacg tgttatgcgc attcattttt
    10981 tctgccgtaa gaatgactcc ggaatggtcc gctgccttgt gtaggcccct cagctcgatt
    11041 tccgcctctg ctttgttttg gtgatcgatg ttgcaaattg tgatattgat atcgccttca
    11101 gcttgtttcg acgctgaaat gctgatttgc ggaagcgttt caccgttcca ttcatagtcg
    11161 gcagacattg tctctgtggc taaaagagaa gcgtcctggt gcaccttaaa catattgaat
    11221 acatggtacg tcggtgtcaa aagcatccgc tctccctcag tcaaaatcat cgcttgaaga
    11281 acatttactg tttgggcgat gttggccatt tgcacccggc ggcaatgctg atggaaaatg
    11341 tggaaatgag aagccgccac cagtgcatca cgaatggtgt tttgctgata taagaaaccg
    11401 ggattcgtgc ctggctcggg atcaaaccac gtgccccatt catcaataat cagcccgacc
    11461 cgctgctccg gatcgtaccg gtccataatc gtgccgtgtt tttgaatcaa ttcatcgatg
    11521 tatttggctt ttttcatcgt aataaaccat tcatcttccg tgaattctgt ggctgatcct
    11581 ttgcccttcc agaaatcccc cggaatcgtg taataatgaa gactcaaccc gtccatcagg
    11641 ccagcagctt ttttcataag cacgtccgtc caattaaaat catccacatt tgcgccgcct
    11701 gcaattttat aaatgtcatt cccgctgtaa ttgcggacat aagtctgaaa acgccggtac
    11761 agatctgcgt agtattcggg atgcatgttg ccgccgcagc cccagttttc attgcccacg
    11821 ccgaaatatt tcagcttcca aggctcttct cttccatttt gctttctcca gtctgacatc
    11881 ggcgtgcctt cttcaaatgt catatactca atccactccg acatttcctg aacggttccg
    11941 cttccgacat tgccgcaaat atatggctcg cattcaagca gctcgcaaag catcataaat
    12001 tcatgcgttc cgaattcatt tgattcaatt gtaccgcccc agtgagtgtt cagcattgtc
    12061 ttacggtcac cgacaccgtt tgcccaatgg tattcgtccg caaaacaccc gcccggccac
    12121 ctgaggacag gaatgtgcag ctgtttgagc gcctccagca cgtcctttcg tatcccgttg
    12181 atattgggga tgtctgagtc cgttccaacc cagatcccct cataaatccc tcttcctaaa
    12241 tgctcagcaa aatgaccgta tatatttttg ttaatggttc cttttacgat atctgtttga
    12301 atcactgctt gatgttcaga catgcctctg atcattcctt tcatacggat atgaaaagca
    12361 ccacagtcaa atatgtgatc tgtcttttgc ctgaggagtc agcatgaatg taagcgcttt
    12421 taaagtaacc atattatata tgttcgtaca tgtcaacgac attttctatt gtttttacat
    12481 ttgtacgtat gtatttataa atatgaaaaa atcccgaact tttaaagtcc gggatttcct
    12541 ttatgagtgt atattcaatt gtttgaattc ctcagttaat aacgggacaa cttcaaataa
    12601 atcaccgacg atgccgtaat ccgctatttt aaagatatcg gcttcggggt ctttattgat
    12661 ggcgacgatc accttgctgt ttgacatgcc ggccaaatgc tggatggcgc cggaaatgcc
    12721 gcatgcaatg tacaaatccg gagtaacgac tttcccggtc tgcccgattt ggagagcata
    12781 atcgcaataa tcagcgtcac atgccccgcg agaagccccg actgcggccc ctagcacctc
    12841 tgcaagctcc tgcagcggct gaaatccttc cttgcttttg actcctcggc cgcccgcaac
    12901 gataattttc gcttcggaga gatcaacacc gtccgccgtt tttttcacga cctcttggat
    12961 aacagtgcgg aggtcagtaa gagaaacatc aatgctttcg atgctccccg atctgctggt
    13021 gtctttttct gaagcttgaa tgttattggg gcgaattgtt gcaaagatca tcggatcggt
    13081 tgaaatgacg cgttcaaaag ctttccccga gtaaatcggc cgtgtgaaca caacattccc
    13141 tccggtaacg cttacatcta tagcatcaga aattaagcct gtttgcagac gggcagcaag
    13201 cttcggtgaa agatccttgc ccattgccgt atgcccgaag atgactgaat caggattttc
    13261 ttgctcgata acacctctca tgatctggct gtacccgtct gccgtgtatg ttttcagctt
    13321 cgggtcctca gcggtaagaa ctttatctgc tccgtaatga ataagctctt gtgcaatgtt
    13381 ttgtacattt tcaccgatga gaacaccgat gacttctcca tctcctgaaa tggttcttcc
    13441 tgcagctatt gcttcaaagg tgacattccg caattcccca tcgcgtattt ctccaagcac
    13501 gatcactttt tttcccattc taacatcccc ctgtttcttt gaatgtccaa gctttaaatg
    13561 actttagctt cgctgcggag caatgagaca agctcttttg cctgttcggc aggctcacct
    13621 tggagaagct tcccggcttc ttttttcggc ggcagaaaac gttcaatggt tttcagcttt
    13681 ggttcagcat cctcttcgtc caggtcaaga tcatcaagtt caagctcttc aagcggcttt
    13741 ttcttagcct tcataattcc cggaagcgat ggatagcgcg gctcgtttaa gccctgctga
    13801 gctgtgacaa gcaatgggag cgtcgttttg attttttcaa catccccttc gacgtccctt
    13861 tctgcttctg catcagtgcc gttgatttcg agtttggtga tcgtagtgat acacggaatg
    13921 tccagtagct cggcaagccg aggcgccact tgtcctgatc ctccgtcaat ggcaacattt
    13981 ccgccgagaa tcaaatcaaa ctcctgatcc ttcatatagt ggtataaaac ttgagaaatg
    14041 gaatattggt cgggttcttc aagatcatct tctatgttga ttaaaacagc ttggtcacaa
    14101 cccatggcaa gcgccgtacg caattctttc tccgcttctt caccgccgac tgtgacagcg
    14161 gtgatcgtgc cgccatgctt ttccttcagc tggatggctt cttctatcgc gtactcatca
    14221 tatggattaa tgatccattc cgctccgtca tcctgaatct ttcctgtttc aatgacgatt
    14281 ttttcttctg tgtcaaacgt ccgtttcatc agtacaaata gattcatgat catatcccct
    14341 tttattcgcc tttgaactga ggctttcttt tttcgagaaa tgcctggatg ccttccttgg
    14401 cgtcctctga ctcaaatgct tccccaaatc gctttgcttc aagctttaag ctgccttcat
    14461 aggaatacac cttgttggaa taaagaagtt caagcaaaga tgccagcgtt tgcgggcttt
    14521 tctctgcaaa cttagcggca agtgcttttg ctttttcaat cacttctgcc tcatctttcg
    14581 ctccaattga gacaagtccg agatcaagcg cttcttttcc ggatatcggt tctcctgatc
    14641 cgatgagctc cagtgctttg gctgtaccga catatctcgg aaggcgctgt gtccccgcaa
    14701 aacctggaat gataccgaga ttaagctccg ggagccccag cttagcatct tctgccgcga
    14761 ttctgatgtg acaggccatt gcaagctcca gcccgcctcc gagagcagcg ccgtgaatcg
    14821 ctgcgataat cggttttgga aaactttcga ttctctccat taactgctgg ccgcgctcag
    14881 cgagcaatga ggaatcctca ttgcctttaa gcgatgtaaa ttctttaata tcagcgccgg
    14941 ctgagaaaaa tcttccctcg ccgtgaatga taatgcttcg tacgcctgca tctgtctcac
    15001 attgatcaag acaggaagac agctcttcta atatccggct tgaaagcgcg tttgccggcg
    15061 gattgtgaat cgtcaagact gccacaaatt gatcaaccgc aagtgaaatt gcattcatag
    15121 gacagaactc ctttacttat tatgaattcc ggacaccaat aattctaaaa cgctgtttga
    15181 aagcgcaacg agatcgtact tttggtcatt catcacccaa gttgtcacag tttcgtcaat
    15241 cgttccaaaa atcatctgcc gggcgaggcg
//
