LOCUS       c00004_gnlPro..        13991 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ALMECFFD_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 11:52:28
            Original ID  :: gnl|Prokka|ALMECFFD_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 153269
            Orig. end    :: 167260
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13991
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[163269:166561]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13292
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13991
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13991
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1101..2363)
                     /locus_tag="ctg4_160"
                     /transl_table=11
                     /translation="MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEI
                     VEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDD
                     VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLI
                     QAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQ
                     GGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLL
                     SKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNV
                     ELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTH
                     GEPPRLLLKDGTEVSQDKTSA"
     CDS             complement(2635..3909)
                     /locus_tag="ctg4_161"
                     /transl_table=11
                     /translation="MSVKWEKQEGNEGVLTVEVDAETFKTALDDAFKKVVKQVSIPGFR
                     KGKIPRGLFEQRFGVEALYQDALDILLPVEYPKAVEEAGIEPVDRPEIDVEKIEKGESL
                     IFTAKVTVKPEVKLGDYKGLGIEKDDTTVTDEDVQNELKALQERQAELVVKEEGAVEEG
                     NTVVLDFEGFVDGEAFEGGKAENYSLEVGSGSFIPGFEDQLVGLEAGAEKDVEVTFPEE
                     YHAEDLAGKPAVFKVKIHEIKAKELPELDDEFAKDIDEEVETLAELTEKTKKRLEEAKE
                     NEADAKLREELVLKASENAEIDVPQAMVDTELDRMLKEFEQRLQMQGMNLELYTQFSGQ
                     DEAALKEQMKEDAEKRVKSNLTLEAIAKAENLEVSDEEVDAELTKMAEAYNMPVENIKQ
                     AIGSTDAMKEDLKVRKAIDFLVENR"
     CDS             complement(4137..5141)
                     /locus_tag="ctg4_162"
                     /transl_table=11
                     /translation="MTHDKKNAKIIPFPHLKDRLVEKGMSSLKEKKYQEALELFSEAMK
                     YDDTESDLHLGMAICFLELGELEEAKSVCEKMLKEGYGHYFTVLQVYMTILIQLKKYEE
                     VKSTIEAVLEENQLPAESAEQFYKLLDFSRKMTDPDREDEAWAEEYEDTIDTEKVLASP
                     EEQMNLIHSLKDRNVAKYTGLLKTILQDPSAHPIIKTMIVMLLAEHEYSKPVHISKFGE
                     SLTIEPSEIVPPDAAPILHRVLRVLDETLGNENPTLYAAVEELWRRHLYVLYPFQPKLL
                     SADLWAAALHKVGYEMHGIEIESEELHMMYEFTDRELDEACTMLKDIEEISYL"
     CDS             complement(5260..5859)
                     /locus_tag="ctg4_163"
                     /transl_table=11
                     /translation="MEPLKSHTGKAAVLNRINVDTDQIIPKQFLKRIERTGYGRFAFFD
                     WRYDANGEPNPEFELNQPVYQGASILIAGENFGCGSSREHAPWALDDYGFKIIIAPSFA
                     DIFHQNCFKNGMLPIRMPYDNWKQLVGQYENKSLEMTVDLEKQLIHDSEGNQISFEVDP
                     HWKEMLINGYDEISLTLLLEDDIKQFESQRSSWLQA"
     CDS             complement(5872..7290)
                     /locus_tag="ctg4_164"
                     /transl_table=11
                     /translation="MMPRTIIEKIWDQHIVKHGEGKPDLLYIDLHLIHEVTSPQAFEGL
                     RQKGRKVRRPQNTFATMDHNIPTVNRFEIKDEVAKRQVTALERNCEEFGVRLADLHSVD
                     QGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRP
                     KTLEVRVDGTLQKGVTAKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMTVCNM
                     SIEAGARAGLIAPDEVTFEYCKNRKYTPKGEEFDKAVEEWKALRTDPGAVYDKSIVLDG
                     NKISPMVTWGINPGMVLPVDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKIEDIKVE
                     HVFIGSCTNSRMTDLRQAADMIKGKKVADSVRAIVVPGSQSVKLQAEKEGLDQIFLEAG
                     FEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGH
                     FVDVRKFYQEKTVV"
     CDS             complement(7340..8437)
                     /locus_tag="ctg4_165"
                     /transl_table=11
                     /translation="LKKRIALLPGDGIGPEVLESATDVLKSVAERFNHEFEFEYGLIGG
                     AAIDEHHNPLPEETVAACKNADAILLGAVGGPKWDQNPSELRPEKGLLSIRKQLDLFAN
                     LRPVKVFESLSDASPLKKEYIDNVDFVIVRELTGGLYFGQPSKRYVNTEGEQEAVDTLF
                     YKRTEIERVIREGFKMAAARKGKVTSVDKANVLESSRLWREVAEDVAQEFPDVKLEHML
                     VDNAAMQLIYAPNQFDVVVTENMFGDILSDEASMLTGSLGMLPSASLSSSGLHLFEPVH
                     GSAPDIAGKGMANPFAAILSAAMLLRTSFGLEEEAKAVEDAVNKVLASGKRTRDLARGE
                     EFSSTQAITEEVKAAIMSENTMSNV"
     CDS             complement(8458..10014)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_166"
                     /sec_met_domain="HMGL-like (E-value: 1.7e-99, bitscore:
                     326.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRKINFFDTTLRDGEQSPGVNLNTQEKLAIAKQLERLGADIIEAG
                     FPASSRGDFLAVQEIARTIKNCSVTGLARCVKGDIDAAWEALKEGAHPRIHVFIATSDI
                     HLKHKLKMTREQVIERAVEMVKYAKERFPIVQWSAEDACRTELPFLAEIVEKVIDAGAS
                     VINLPDTVGYLAPAEYGNIFKYMKENVPNIHKAKLSAHCHDDLGMAVANSLAAIENGAD
                     QIECAVNGIGERAGNAALEEIAVALHTRKDFYQVETGITLNEIKRTSDLVSKLTGMAVP
                     RNKAVVGDNAFAHESGIHQDGFLKEKSTYEIISPELVGVTADALVLGKHSGRHAFKERL
                     TALGFQFDSEEINKFFTLFKELTEKKKEITDEDLVSLILEEKVTDRKIGYEFLSLQVHY
                     GTSQVPTATLSLKNQENAQLIQEAATGAGSVEAIYNTLERCIDKDVELLDYRIQSNRKG
                     EDAFAQVYVRVLVNGKESAGRGIAQDVLEASAKAYLNAVNRQLVFQSNMSGLKNHTAVG
                     S"
     CDS             complement(10001..11029)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_167"
                     /sec_met_domain="IlvN (E-value: 1.5e-77, bitscore: 252.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 5.2e-68, bitscore: 221.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIV
                     GVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLV
                     FAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDK
                     ALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPEL
                     AYFECLHELKLIVDLMYEEGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDI
                     QNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVSVA
                     QN"
     CDS             complement(11053..11571)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_168"
                     /sec_met_domain="ALS_ss_C (E-value: 2.9e-31, bitscore:
                     101.0, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSR
                     ITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEING
                     IIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKA
                     SSNKTISIV"
     CDS             complement(11568..13292)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_169"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-54, bitscore:
                     177.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTNVQVDSASAECTQTMSGALMLIESLKKEKVEMIFGYPGGAVL
                     PIYDKLYNSGLVHILPRHEQGAIHAAEGYARVSGKPGVVIATSGPGATNLVTGLADAMI
                     DSLPLVVFTGQVATSVIGSDAFQEADILGITMPVTKHSYQVRQPEDLPRIIKEAFHIAT
                     TGRPGPVLIDIPKDVATIEGEFSYDHEMNLPGYQPTTEPNYLQIRKLVEAVSSAKKPVI
                     LAGAGVLHGKASEELKNYAEQQQIPVAHTLLGLGGFPADHPLFLGMAGMHGTYTANMAL
                     HECDLLISIGARFDDRVTGNLKHFARNAKIAHIDIDPAEIGKIMKTQIPVVGDSKIVLQ
                     ELIKQDGKQSDSSEWKKQLAEWKEEYPLWYVDNEEEGFKPQKLIEYIHQFTKGEAIVAT
                     DVGQHQMWSAQFYPFQKADKWVTSGGLGTMGFGLPAAIGAQLAEKDATVVAVVGDGGFQ
                     MTLQELDVIRELNLPVKVVILNNACLGMVRQWQEIFYEERYSESKFASQPDFVKLSEAY
                     GIKGIRISSEAEAKEKLEEALTSREPVVIDVRVASEEKVFPMVAPGKGLHEMVGVKP"
ORIGIN
        1 cagccatccc cgctgcgatt tgaatcatat tgacggcttc ccgcccgttc cgcgtgtagc
       61 tggtcaaaag atccagtcct tcttcggaga tatttttttc aattttatcc gctgctgttt
      121 tggcaaccgt tttcaactcg tccttttcaa gctcgcggaa aaaaacctcc aaacagcggg
      181 accggatagc tggcggaatt tcgtttggca ttctcgtggt cgcgccaatc aagcgaaaat
      241 cagccggcag cccattttga aaaatatcat gaatatgatt cggaatttgt gtattttcct
      301 cactgtaata cgcactatct aaaaagactt ttctgtcctc aagcaccttc agcattttat
      361 tcatttgaat aggatgcagc tcccctattt catcaataaa cagcacaccg ccatgggcat
      421 gggtgacagc tccctgcttc ggctgcggaa tcccagcctg tcccatcgct ccggcccctt
      481 ggtatatcgg gtcatggaca gagccgatga gcggatcggc aattcctctt tcatcaaaac
      541 gggctgttgt cgcatcgagt tccacaaaga cagcctgctc tttaaacggt gattgtttat
      601 gtttttttgc ttcttccaac acaagccgcg cagcagccgt tttcccaact cccggtggcc
      661 catagacaat cacatgctga ggatttggcc cgcataaagc cgcctttaat gctttaatgc
      721 cgtcttcctg tccgacgata tctttaaagc ttttggggcg gaccttctca gataatggct
      781 cggacaagct gatagcgcgc attttccgaa gctgctccat ttccttcttt gattctttat
      841 ctatcgtgac cttttgtgtc ctttgattct taagcaaatt ccaaaaatac aaaccgatga
      901 tgatcccaaa aaacagctga ataaataacg cgatccctgt ccaactcatg gtggtccctc
      961 ctgaaaaaca atttatgtat ccaattcatt cctctgattg ctagtatctc ccatagaaga
     1021 cgggaataaa cgtttttccg gaagagttgc atgcaaaaaa acctcctgag tgttaccact
     1081 caggaggttt gtgcttatct ttatgcagat gttttatctt ggcttacctc agtgccgtct
     1141 tttaataaga ggcgaggagg ctctccgtgt gtcacagttg ccccggtgat tacacatttt
     1201 tcaatgtcat cacgagaagg cagctcaaac atcacatcaa gcatgatgcc ttcaatgatg
     1261 gaacggagtc cgcgtgctcc agtcttgcgt tcaattgctt ttttagcaat ttcagaaagc
     1321 gcttcttctt caaactcaag ctcaacgttg tcaagctcaa gcattttctt gaattgctta
     1381 actagagcgt ttttcggttt tgttaagatg gcaaccaatg cttcttcgtc aagcttttca
     1441 aggcttgcaa taaccggaag acgtccgata aattcaggaa ttaacccgaa acggagcaaa
     1501 tcttcaggaa gcacttttga aagaagatct tctttctcaa gatcagcagc tttattgtcg
     1561 gcaccgaatc caatcacttt ttggcctaaa cggcgtttga tgatttgttc gataccatcg
     1621 aaagctccgc cgcaaatgaa caaaatattt gttgtgtcaa tttgaatgaa ttcttgatga
     1681 ggatgcttac gtccaccttg aggcggtacg cttgccactg taccctcaag aattttaagc
     1741 aatgcctgct gtacaccctc acctgacaca tcacgtgtga tagacgggtt ttcagatttt
     1801 ctagccactt tatcgatttc atcaatatag ataatgcctt tttcggcttt ttccacatca
     1861 taatcagcag cttggatgag cttcaagaga atattctcta catcttcacc cacgtatcca
     1921 gcttcagtca aagatgtagc gtccgcaatc gcaaacggca catttaaaat gcgagccaat
     1981 gtttgcgcca gaagggtttt accgcttccc gtagggccga ttaatgaaat attacttttt
     2041 gagagctcaa catcatcaac tttgctgtta gagttaatgc gcttatagtg gttatacaca
     2101 gcaacagcaa gtgatttctt cgcttgatct tggccgatga catattcatt caaaatttcg
     2161 cgaatttcct gaggctttgg tacgtcttta aattctactt cttcttctgt tccgagttct
     2221 tcctctacaa tttcagtgca gagttcgata cattcgtcac atatatatac accaggccca
     2281 gctacaagct tacgaacctg atcttgtgtt tttccacaga acgagcattt taattgtcct
     2341 ttttcctcgt taaatttaaa cattctttca ccccttaatc ttgtctcact ttttctttta
     2401 ccggcagagc aaaagaaaat gattcttgaa acgaacgagt atgtattgca ttttaccata
     2461 ctttccaaaa agacggtaac aatgtgtttc tgacttgcac attctatatg tatgacaaaa
     2521 aacagccctg cattaactat attgccccaa gaaaaagaga taactcataa ttgtacaaaa
     2581 caaggcacga atgattcgcg ccctgtttta ttagtactat tattatgcac catattaacg
     2641 gttttctaca agaaaatcaa ttgctttgcg aacttttaaa tcttctttca tcgcgtcagt
     2701 agaaccgatg gcttgtttaa tattttcaac aggcatgttg tatgcttcag ccattttagt
     2761 aagctcagca tcaacttcct catctgatac ttcaaggttt tccgctttcg caatcgcctc
     2821 aagagtcagg ttagatttta cgcgtttttc agcatcttct ttcatttgct cttttaacgc
     2881 agcttcatct tggcctgaga attgagtgta aagctcaagg ttcatgcctt gcatttgcag
     2941 acgctgttcg aattctttca gcatgcggtc aagctcagta tcgaccattg cttgaggcac
     3001 atcgatttca gcattttcag aagctttcag aacaagctct tcacgcaatt tagcgtcagc
     3061 ttcgttttct tttgcttctt ctaaacgttt cttagttttt tcagttaatt cagcgagtgt
     3121 ttccacttct tcatcgatat cttttgcgaa ttcatcgtca agctcaggaa gctctttcgc
     3181 tttgatttcg tgaattttca ctttgaacac agctggtttg cctgcaagat cttcagcgtg
     3241 gtactcctca gggaatgtca cttcaacatc cttctcagca cctgcttcaa ggccaactaa
     3301 ttgatcttcg aagccaggga tgaatgaacc agaacctact tctagagagt agttttcagc
     3361 ttttccgcct tcgaatgctt cgccgtcaac gaatccttcg aaatcaagaa caactgtgtt
     3421 tccttcttca acagcgcctt cttcttttac aacaagctca gcttgacgct cttgaagcgc
     3481 ttttagttcg ttttgaacat cttcgtcagt tacagttgtg tcgtcttttt caatgcctaa
     3541 gcctttgtag tcgccaagct tcacttcagg ttttactgtt actttcgcag tgaagattaa
     3601 gctttcgcct ttttcgattt tttcaacatc gatttcagga cggtctacag gctcgattcc
     3661 agcttcttca accgctttag ggtattctac aggaagaaga atatccaaag catcttggta
     3721 aagagcttct acgccaaagc gctgttcgaa taatccgcga ggaattttac ctttacggaa
     3781 tccaggaatt gaaacttgtt ttactacttt tttaaatgca tcatcaagtg ctgttttaaa
     3841 cgtttcagca tcaacttcaa ccgttaaaac gccttcgttg ccttcttgtt tttcccattt
     3901 tacagacatg tgtttccctc caaaaatcta ttcaggttgt gtcggtcttc cattctaaag
     3961 caatcatacg gcttcgtcca acaaaaacaa agctgccaaa gatcagaatc attatgtata
     4021 gatgttaata atgaactgca aagcctgtcc aaccgtattt cttataaccc gttatacaca
     4081 aatacaacca ttatattata acataacaca tagcgctttc aactatatgg cgcgatttac
     4141 aaataagaaa tttcttcaat atcttttaac attgtgcaag cttcatcgag ttctctgtcg
     4201 gtaaattcat acatcatatg aagttcttcg ctttcaattt caattccgtg catctcgtaa
     4261 ccgactttat gcagggcagc cgcccaaagg tcagccgaca gcaatttcgg ctggaacgga
     4321 tataaaacgt ataaatgtct tctccacaat tcttctactg ccgcatataa ggttggattt
     4381 tcatttccaa gtgtctcatc cagcaccctg agaacacggt gcagaatcgg ggcggcatca
     4441 ggcggaacaa tctcagatgg ttcaattgtc aacgactcgc caaatttgct aatgtgcaca
     4501 ggtttactgt actcatgctc agccaacagc atgacaatca tcgttttgat aatcgggtgg
     4561 gctgaggggt cttggaggat tgttttgagc aatcctgtat actttgctac gttacggtct
     4621 tttaaggaat gaatgagatt catttgctcc tcagggcttg ccagcacttt ctcggtgtca
     4681 attgtatcct catattcttc ggcccaagcc tcgtcctcac gatccggatc ggtcattttc
     4741 cggctgaaat ccagcagctt ataaaattgc tcggcgcttt ctgccggcag ctgattttct
     4801 tccaaaacgg cttcaatggt gcttttgact tcctcgtatt ttttgagctg aattaagatg
     4861 gtcatgtaca cctgcaaaac cgtaaaataa tggccataac cttctttgag catcttctcg
     4921 cacacgcttt ttgcctcttc cagctcgccc agctctaaaa agcagatggc catccctaag
     4981 tgaagatcgg attcagtatc atcatatttc atcgcttctg aaaacagttc aagcgcttct
     5041 tgatactttt tttcctttag tgatgacatc cctttttcca caaggcggtc tttcagatga
     5101 ggaaaaggaa taatttttgc gttcttcttg tcatgcgtca tacctatatt cctttcaggc
     5161 atttattttg ttcaagtgta tcaacacctg tgaacaaaca caagaaatga aaggtttcat
     5221 caggcaaaaa aagccgccgg acaaataccg gccgcttttt caggcttgaa gccaagagct
     5281 tctttgtgat tcaaattgct taatgtcatc ctccagcagc agcgttaagg aaatttcatc
     5341 atatccgtta atcagcatct ctttccaatg cggatcaact tcaaatgaaa tttgattgcc
     5401 ttcactgtca tgaatcagct gcttttcaag gtcaacagtc atttccaatg acttgttttc
     5461 atactggccg acaagctgtt tccaattgtc atatggcatg cggatcggaa gcatgccgtt
     5521 tttaaagcag ttctgatgga aaatatcagc aaatgacggc gcaatgataa ttttaaaccc
     5581 ataatcatca agtgcccacg gagcgtgttc acgcgatgac ccgcagccga agttttctcc
     5641 tgctattaaa atggaagctc cttgataaac aggctggttt aattcaaatt cagggttcgg
     5701 ttcaccattc gcatcatatc tccagtcaaa gaatgcaaaa cgcccgtagc ctgttctttc
     5761 aatcctcttc aaaaattgct taggaataat ctggtctgta tccacattga tccgatttaa
     5821 tacggctgct ttccccgtat gtgatttcaa aggttccatc tcgcgcactc cttacacaac
     5881 tgttttttcc tgataaaact ttctgacatc aacgaagtgt ccgtgaatgg cagccatcgc
     5941 agccattgcc gggctgacga gatgtgttct tgcacctttt ccttgtctgc cctcgaagtt
     6001 gcggttagag gttgatgcac agcgctctcc ctcaggaaca acatcattat tcatactcaa
     6061 acacatgctg cagcctgact ctctccattc aaatccagct tccaagaaaa tctggtcaag
     6121 cccttctttt tcagcctgaa gcttcacgct ttgggatccg ggcacgacga tggcccttac
     6181 gctgtcagct accttcttcc ctttgatcat gtcagcagcc tgtcgaaggt cagtcatgcg
     6241 ggaatttgtg caggaaccga taaatacgtg ctccacttta atgtcttcaa ttttctgatg
     6301 aggagtcagt cccatatatt cataagcgcg aatcgcttct tttttatcat cttctgcaga
     6361 aaagctttcc ggcgcaggaa cttcagaatc gacaggaaga accattcccg ggttaatgcc
     6421 ccatgtcacc ataggggaaa ttttgttgcc gtcaaggacg atagatttat cgtaaacagc
     6481 gcccgggtct gtgcgcagcg ccttccattc ctctacggcc ttgtcaaatt cttcgccttt
     6541 tggcgtgtac ttgcgatttt tgcaatattc aaacgtcacc tcgtcaggtg caatcaaacc
     6601 tgctcttgct cctgcttcaa ttgacatgtt acaaacggtc attcgttcat ccatcgtcat
     6661 atttctgaat acttccccag tgtattcaat gacgtagcct gtgccgaatt tcacaccgta
     6721 tttgccgatg acagcaagga tgacatcctt tgccgttacc cctttttgaa gcgttccatc
     6781 tacgcgcact tcaagtgttt ttggacgctg ctgccaaagt gtctgtgtgg aaaggacatg
     6841 ttcgacttca ctcgtcccga ttccaaatgc aagagcgccg aaagcgccat gtgttgatgt
     6901 atgactgtca ccgcacacaa tcgttttccc tggaagcgtt aagcccagtt cagggccgac
     6961 gacatggaca atcccttgat ccacgctgtg aagatcggca aggcgcacgc caaattcctc
     7021 acagtttctt tcaagcgccg ttacctggcg tttcgcaact tcatccttta tctcaaaacg
     7081 attgacagtc gggatgttgt ggtccattgt cgcaaatgtg ttttggggtc ttctgacctt
     7141 tcttcccttt tgtctcaagc cttcaaatgc ctgaggagac gtcacctcat gaatgaggtg
     7201 caaatcaata tagagaagat ccggctttcc ctcaccatgt tttacaatat gctgatccca
     7261 aatcttttcg atgattgttc gaggcatcat cttttatttc ctccctctac ctagagctaa
     7321 gaccgcttaa cgtaagctgt cacacattag acattgtatt ttcactcatg attgctgcct
     7381 taacttcctc tgtaatggcc tgagtgctgc tgaactcttc accccgtgcc aagtctcttg
     7441 ttctttttcc agaagccaag actttgttta ccgcatcttc tacagctttc gcttcctctt
     7501 caagcccgaa agatgttctc aaaagcattg ccgctgacaa tatggctgcg aacggatttg
     7561 ccatcccttt accggcaata tcaggcgcgg agccatgaac aggttcaaac agatgaaggc
     7621 cagagcttga taggctggct gacgggagca ttccgagcga gcctgtaagc atggacgctt
     7681 catcgcttaa gatatcaccg aacatatttt cagtcaccac gacatcaaat tgattcggtg
     7741 cataaattag ctgcatggcc gcgttatcca caagcatgtg ctcaagcttc acatcaggaa
     7801 actcttgtgc aacgtcctca gccacttcac gccacagccg gcttgattca agaacattcg
     7861 ctttatctac agaggtcact ttgccttttc tggctgccgc cattttgaag ccctctctga
     7921 tcactcgttc aatttccgtt cgcttataaa acagtgtatc tactgcttcc tgctcacctt
     7981 cagtgtttac atagcgtttg ctcggctggc cgaaatacaa gccgcctgtg agctcacgaa
     8041 cgataacgaa atcaacatta tctatatatt cttttttcaa aggcgaagcg tcagaaaggc
     8101 tttcaaatac cttcacaggc cgcaaattcg caaacaaatc aagctgtttt ctgatgctga
     8161 gcagcccttt ttccggtctc agttccgaag gattttgatc ccatttcggt ccgccgacag
     8221 cgccaagcaa tatcgcgtct gcatttttac aagcagcaac agtttcctcc gggagggggt
     8281 tatgatgttc atcaatagcc gcccctccaa tcaggccata ttcaaattca aattcatggt
     8341 taaagcgttc ggcaacactt ttcagtacgt ctgtcgctga ttctaatact tcagggccga
     8401 tcccgtctcc gggcaataga gcaatacgtt tcttcaagtt aaccgttctc ctttctttta
     8461 tgatccgaca gctgtatggt ttttcaatcc gctcatattc gactggaaaa ccaattgacg
     8521 atttactgcg ttcaaatagg ctttcgctga tgcttctaat acgtcttgcg ctatgccccg
     8581 ccctgctgat tcttttccgt tcaccaaaac tcttacatac acctgggcaa atgcatcttc
     8641 gccttttcta ttagactgaa tgcggtagtc taagagctcc acgtccttat cgatgcagcg
     8701 ctcaagcgta ttgtagattg cttccacgct tccagctcca gttgcagctt cctgaataag
     8761 ctgtgcgttt tcttgatttt tcaaagaaag agtagccgta gggacctgac ttgttccgta
     8821 atgtacttgc agagaaagaa attcataacc aatcttgcga tctgttactt tttcttctaa
     8881 aataagagaa acaagatcct catcagtgat ttcttttttc ttctcagtca actctttgaa
     8941 caacgtaaag aatttattaa tctcttcact gtcaaattgg aatcctaaag cagtcagccg
     9001 ttctttaaat gcgtgacgtc cggaatgttt acctaggaca agcgcatctg cggttacgcc
     9061 gacaagctcc ggtgaaataa tttcataagt cgatttttcc tttaaaaagc cgtcctgatg
     9121 gatgcctgat tcatgagcaa atgcattatc tccaacaacc gctttgttgc gcgggacagc
     9181 catgcctgtc agtttgctta ctaaatcact tgttctctta atctcgttca gcgtaatacc
     9241 tgtttcgact tggtagaaat cttttctggt atggagggct acggcaattt cctctaatgc
     9301 cgcgtttccg gctctttcac cgatcccgtt cacagcgcat tcgatttgat cagcgccatt
     9361 ttcaatcgca gcaagagagt ttgcgactgc cattcccaaa tcatcatgac agtgggctga
     9421 aagctttgct ttgtgaatgt tcggaacgtt ttctttcatg tatttaaaga tatttccgta
     9481 ttccgccggg gccaggtagc cgacagtgtc cggaagattg ataacactgg cgcctgcgtc
     9541 aatcactttc tcgacgattt ctgctagaaa cggcagttca gtgcggcagg catcttcagc
     9601 tgaccattgc acaatcggaa aacgttcttt tgcgtatttc accatttcaa ccgctctttc
     9661 aatgacttgc tcacgtgtca ttttcagctt gtgcttcaaa tgaatgtccg atgtggcgat
     9721 aaaaacatgt attctcggat gagcaccttc ttttaacgct tcccaagcag catcaatatc
     9781 accttttaca caacgggcca gaccagttac tgaacaattt ttaatggttc ttgcgatttc
     9841 ctgaacagct aaaaagtcac ctcgggacga agcgggaaat cccgcttcaa tgatatctgc
     9901 cccgagtctt tcgagctgct tagctatggc aagtttctcc tgtgtattca agttcactcc
     9961 aggggactgt tcaccatcac gaagcgtcgt atcgaaaaaa ttaattttgc gcaacggaga
    10021 ccaccgcttc cttcttcttg ccttgtttca caaacggcat catttcacga agctttcttc
    10081 ccactacttc gatttgatgt tcgttctcgc ttgcattgat agcgttgaaa cgaggacggt
    10141 ttacttggtt ttcgacgatc cactcttttg cgaatgtacc gttttggata tcttttaata
    10201 cttctttcat agattctttt actttagcgt ccacaacgcg aggacctgat acgaaatctc
    10261 cccactgtgc tgtgtcagag attgaatatc tcattcctgc aagtccttct tcgtacataa
    10321 ggtctacgat taatttcagc tcatgaagac actcgaagta tgcaagttca ggctgataac
    10381 ctgcttcagt taatgtttca aatccggctt tgacaagcgc gcttaatccg ccgcaaagaa
    10441 ctgcttgctc accgaacaaa tctgtttctg tttcttcttt aaatgtcgtt tctaatacgc
    10501 ccgctcttgc gccgccgatt cctttagcat aagcgagggc tttgtctctt gcttctccag
    10561 tcacatcttg atagattgcg aacaatgccg gtacgccagc tccttgctca tatgttcttc
    10621 ttaccaagtg tcccgggcct ttaggggcca ctaagaatac atctacatcc gccggaggaa
    10681 caatttgatg gaaatgcacg ttaaatccat gagcgaatac taatgatttt cctgctgtca
    10741 attcatcttt gatttcagct tcgtatactt tttgctgctg ctcatccgga agcagaacca
    10801 tgatgatttc agcttgggct gccgcttctt ttactgaaaa tactttatgt ccgtcttctt
    10861 gggcttgagt gaaagatttt ccttgtctaa caccgacgat cacgtctact ccgctttctt
    10921 taaggttcag ggcatgtgcg tggccttgcg aaccataccc gataaccgct actgtttttc
    10981 cagccaatac gttctctttg atatcaccgt tataatatac ttttaccatt ttaatctctc
    11041 ccttgttatg ttttatacaa tagatattgt tttattggat gacgcctttt gctgggttcc
    11101 cctcgcaaaa gccgttgtac ctgttctcgc gatttcttta atgccataag gttttaataa
    11161 ttcaataagc gcttcaattt tgttagattc acctgtcacc tgaacaacga tgctgtctct
    11221 gctgacatca acgacagagg ctctaaacgg ttctatgatt ccattaatct ctgttctcgt
    11281 tgaaggtgcg gagacaacct tgattaaggc cagctccctc tggacaatcg attgatttgt
    11341 gatgtccgtg actttcagca catcaatctg tttgttgagc tgtttcgtta actgttcaac
    11401 atcattttct ccttcaacgt gaacgacgaa ggtgattctg gaaacgccgg ctgtttctgt
    11461 gtgtccaact gtaatgcttt caatgttgta atgccttttt gtgaatagac cggtgatccg
    11521 gtttaacacc ccggagcggt tcaccacagt caatgtgata attcttttca aggtttcacc
    11581 cccaccattt catgcagccc tttccccgga gccaccatcg ggaatacttt ttcttcgctg
    11641 gcaacccgca cgtcaatgac aacaggttct cttgatgtca atgcctcttc cagcttttcc
    11701 tttgcttccg cttctgatga aattctgatg cctttaatgc cgtatgcttc ggacaatttg
    11761 acgaagtcag gctgagaagc gaatttagat tctgaataac gttcttcata gaaaatttcc
    11821 tgccactgtc tgaccattcc gagacaagcg ttatttaaaa tcactacctt gaccggaaga
    11881 tttaattcgc gaataacatc gagttcttgg agcgtcattt ggaatccgcc gtctccgaca
    11941 accgcgacaa cagtagcatc tttttcggcc agctgtgcgc cgatcgccgc cggaagaccg
    12001 aatcccatcg ttccaagtcc gcctgacgtg acccatttat ctgctttttg gaacggataa
    12061 aattgcgctg accacatttg atgctggcct acatccgttg cgacaatggc ctctcctttt
    12121 gtaaattgat gaatatattc aatcaatttc tgaggtttaa aaccttcttc ttcattatct
    12181 acataccaga gcggatactc ttctttccat tcggcgagct gttttttcca ttcgcttgaa
    12241 tcgctttgtt tgccgtcttg tttgatcagc tcctgcagga caattttgct gtctccgact
    12301 acaggaatct gtgttttcat gatttttccg atttcagctg gatcaatatc gatgtgagca
    12361 atctttgcgt ttctggcaaa gtgtttcagg tttcctgtga cacggtcatc aaaacgggcg
    12421 ccgatactga ttaatagatc acattcatga agggccatat tggctgtata agtaccgtgc
    12481 attcccgcca tccccaggaa aagcggatgg tcagccggga agcctccgag ccccaaaagg
    12541 gtgtgtgcca cagggatttg ctgctgttca gcataatttt ttaattcttc tgacgctttt
    12601 ccgtgcagta cgcccgcacc cgccaggatc accggttttt tcgcactgct cacggcttcc
    12661 acaagcttgc ggatctgcaa ataattcggc tctgttgtcg gctggtatcc cgggagattc
    12721 atctcatgat cgtagctgaa ttctccttca attgttgcca catctttcgg aatatcaatc
    12781 aatacaggtc cgggtcttcc agttgttgca atatgaaacg cttctttaat gatgcgcggc
    12841 agatcttccg gctggcgaac ctggtagctg tgttttgtca ctggcatcgt aatccctaaa
    12901 atgtccgctt cctgaaatgc atcgctcccg attacagagg ttgctacctg ccctgtaaag
    12961 acgactaacg gcaatgaatc aatcatggca tcagcaaggc ctgtaacaag gtttgtcgct
    13021 cccggtcctg acgtggcaat gacgacaccc ggttttccgg agactcttgc gtatccctcc
    13081 gctgcatgaa ttgcgccttg ttcgtgacgg ggaaggatat gtaccaaccc tgaattgtat
    13141 agcttatcgt aaatcggaag cacagccccg cccggataac cgaagatcat ttctactttc
    13201 tcttttttta atgattcaat cagcattaat gctccgctca tcgtctgtgt acattcggca
    13261 gatgctgaat ccacctgtac attagtcccc attttagttc ctccttttgg attttcatcc
    13321 tttaaagatc atcttttcat tatctagata gctgattatt caataaaaaa agcccttccg
    13381 cccacaatca gccgcgcagt aactgcgata gctaaaaggg gcgaaaaggc ttttctttcc
    13441 gcggtaccac ccttgtttac ggcctgttaa tcggccgtct catggatatt tctatccgct
    13501 ttagtaacga gtgaatcaag ttcacccggc caagtcctac tgtcatttca gactggcact
    13561 ctgaggcgag ttcaccttgt aaagcttcgc cggttctcag ctaacccggt tctctgtgga
    13621 aaactttatc aaggctactt atcctcatct gcgcttttca tattcagcct tcggaacggc
    13681 tttccagctg ttcaagaagg tcgtttgttt ttcatttttt tagaatcata ctgcgatgat
    13741 tttcgcttgt gaagcttgcg tttatctttt gttgaactca tattacgccg ctttggacgc
    13801 agtgtcaaca gcatttttta aaattattag acaatttcga ttaatcaaac tatattgtat
    13861 acgctttcat tattggtaca aaaggaattg caaatgttaa aagtttttat aattttttta
    13921 ttaatctatc aagaataaac cagaattatt taattttata taaacatgta agattttata
    13981 acacgatatg g
//
