LOCUS       gnlProkkaMLEOMEED_69   11119 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MLEOMEED_69.
ACCESSION   gnlProkkaMLEOMEED_69
VERSION     gnlProkkaMLEOMEED_69
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 11:07:46
            Original ID  :: gnl|Prokka|MLEOMEED_69
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11119
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11119
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[849:1119]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      850..1119
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11119
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11119
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             116..850
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 103.3; E-value:
                     2.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="MITAEECRTYKEFVDLYQSYLYPLLGARLSRMYSPKNKVIIDMGT
                     GPGYLSIQLAKRTNAHVHAVDINPAMHEIAQEEAKKSGVSSLISFDLEDVHHLSYADQY
                     ADFIVSYSCLHHWEDVVKGLKECYRVLAPGGKIVILDTFNPQGSHLEIMRKQIKEPEYF
                     RFVREAFEESYSFEDIHQFVQDAGIPNYSLETFHFLPEDFIESLDELEDAPLWEQNDQS
                     TDHEIESVTWMLTIEKEKEGAL"
     CDS             850..1119
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="PqqD_RRE (E-value: 3.6e-10, bitscore:
                     30.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.9e-13, bitscore: 40.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.7e-10,
                     bitscore: 30.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINESTVLSKNPEMPSRKYLKSIIIEPGITLNEMASDIYNHIDGK
                     VSIHDICSKIVNEYDVDYQTCLEDCMELFELLIDHEAIKVKQGA"
     CDS             1123..1605
                     /locus_tag="ctg61_3"
                     /transl_table=11
                     /translation="MEKQKVLALPDDVHELSTHRSKSIVNYIITLLAFAKKQGLTHQDI
                     VSWIHEQYEERGYYDEWRHINSQQPVGSFVELFIKGRRLLYDKIELFETEDKYVVNTHT
                     WYEKEPSEAFFYFEIDPEEFSAYASILAIENAKRLGIKIDIVKETDVETAYIYKHQ"
     CDS             1626..3869
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 407.1; E-value: 2.2e-123)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_4"
                     /sec_met_domain="GATase_7 (E-value: 2.2e-45, bitscore:
                     144.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 5.9e-96, bitscore:
                     312.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGIINLAAPRSQECTFHILKGMADAISYRGPDDEQYHIDSK
                     VGFAFRRLSILDLVNGQQPFLNEDGSIVVMVNGEIYNYKELKASLHNHMFKTTSDCEVI
                     VHLYEEKGIGFVDDIIGMFSIAIWDKNKNKVFLVRDRFGIKPLFYTELKHELIFASEIK
                     SLFSHPHCPRQFNWKEALSDIWLSGEAASNHKETTSFFVNIQNLDAGHYLEINLTTNER
                     KTASYWSLQDILLRQGYRENLHPDDLIEGYRELLADSVHRCLQSDVEVGLFLSGGIDSA
                     AVAHFAAEKQDLHTFTVLSQSTFTNEDAKYAHWLAKDLHLPNHQVLYQLGNDELLQPES
                     YKHLLWICETPFCGPEQLYKFHLHKYAKAIRPNLKVMLTGQGSDEFNGGYSTTLSPAEN
                     PSWEGFIESVNTMEMNRLHRLQGNIFRVWEEHFGLSPINLSYLKSNDSSQADPWQSYVL
                     TKYRDLQMYNCWHEDRIAAANHIENRVPFLDHRLVEWVCGIPDGLRKDLLWDKSVLRKS
                     LTNELHTSYTHRPKVPFFYGKDVRYTHKMMFHLLKKNNYQLIEEAFSHSDASSIIQVEH
                     IHAIMTYLEDDPEFTNFEFLLRLVNMGLLSKMTKETPSVQLDITSHLESITIKDWHSQE
                     GDIASRLNISANKCEGQDILALNPGVTLLRPESDSEHCIYIAEEGFIQFIVSEEDVGAW
                     LHILCDINGKDTLHTILDRHGVSLEEVAKYIQEAIEHNIILIKQKNLPEGAYR"
     CDS             3866..5065
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 100.3; E-value: 1.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg61_5"
                     /transl_table=11
                     /translation="MSIFYSFSALRGLAMGIFSPIWILYLISKDYDFLQIGLMGAVLEI
                     AKLIFEVPSGVFADRYGIKISIASSFFFSILTWAFFPFIDSAAICILAMIIWALSDSLI
                     SGSFETWMSRVAGEDRFGKEMMKNTQLLITFLIIGSIASGYLYSLNIYFPFLLVMVIYL
                     LLFIWMSVFIKVPSVSETNHGDQNQHDSIKIIKESLKIIFNKKRVLLIVIAGFFTATAY
                     DTISRYWQPFLSDLGFSEKSLGYIFALEGFTALVLLTLTIRFEKKIEKNPYLALTSLDS
                     MGMVMTFLLSRAFRPLGIPCTAFLLAIEDIHHPIVTSYLNKFFPDSYKNTLFSLNSGVG
                     AIGEILSGVIFGIISAAFGLSAMFVVVAVFLLIPIILYTIVPKIKDNDMKVQIEKSQQV
                     "
     CDS             complement(5129..6055)
                     /locus_tag="ctg61_6"
                     /transl_table=11
                     /translation="MIDGDGTVYLHSRDGEMKAFNPDGSVKWVTGNLGKTYTQSPVLGT
                     NGVIYLASYDKKIYFIDKETGEILTTVPLSGGPSSETVIGSDGTLYFSTLDNYVHAIKP
                     TSKSTWTERWKLKTNGVVSSVPVLAKNGTVYVGTYNYVFYAINSGTGQVKWSRTTSNAF
                     KGYPVIDKDGNIYAGNQDGQLYAYTSTGSLKWTFPLNGFSSSSPAIDHNGNIYIGSGSG
                     ELFSISKNGDMNWSFYTDGPVRTAPLIDAKGTVYFGSDDMKVYAADANGNELWSYQTDS
                     NVVSSPQLAEDGTLYIGSYTKLMAFGK"
     CDS             complement(6462..6887)
                     /locus_tag="ctg61_7"
                     /transl_table=11
                     /translation="MSKKNSVAIMTTISAFLFCAVIVAASLSPLAGTGAAANQFNSAGM
                     WSAVGMILVLYFIPFLVYMLGVDAMRYVMAVLCGFGLLIHLSSAGFILMFSFFSDHLLS
                     EVIFVLGVSLAAAAVNVIWFVAAFRSGAEKTSVNTLT"
     CDS             7144..7599
                     /locus_tag="ctg61_8"
                     /transl_table=11
                     /translation="MEKPAGFWIRFLAYFIDGIIVSVPSYIILFIINSVFVAGAVATNP
                     YMTEEEYLVKYMTLAFLPTMLIMIVISVLYYGLLTASKMQGTLGKKILGLKVVNEQGER
                     VSVGQGIGRYFAYILSGIIFYIGFIMIAFGEKKGLHDIICKTRVVYK"
     CDS             complement(7629..8837)
                     /locus_tag="ctg61_9"
                     /transl_table=11
                     /translation="MSSLQPTLTNERIGVLDVLRGMAIFGILFVNLAHFSYPDMYLSML
                     GKENFFMDKWSEADFAAADILKFFIQTKCILLFSFLFGFGMVVMMERAENKGKRFVPLY
                     VRRLMALLLFGTIHAFLIWDGDILTEYALLGFVLLLFRKAKPKTLLIWAVSLYLLFSIP
                     FMLTSFDQSNGQEWVQAVTQQAKQAIHVYGSGSLKDIAEQRIHDRLVYMSSNGMLTYNP
                     LNYFFASIPYFSMFLLGAAAAKSRYLHEPEKHRKGLKRLWMAGLVIGIGAQVLYSVTDK
                     EICLLIGAPFLMFFYVTTVVYLYHKTRVRTVLQSFSAVGRMAFTNYLMQSIVCTWIFYH
                     YGLGLYGKVYPAAGVLITIAVCAVQMVFSHLWLRVFRMGPFEWLWRSATYLSWQPIAKK
                     TKV"
     CDS             complement(8945..9826)
                     /locus_tag="ctg61_10"
                     /transl_table=11
                     /translation="MFEIVLLSGGKGDAFPLHVHKDTHEGILVLDGKLELTLDGERYLL
                     ISGDYANIPAGTPHSYRMQSHRTRLVSYTMKGNVAHLYSVIGNPYDHAEHPPYASEEVS
                     NERFAEAAAVADIVFLDEAKPACSAKLAELTELPDGAVPYVLESGEGDRLLTGDQLHRI
                     VAAQKNTDGQFIVVSSEGPKGDRIVDHYHEYHTETFYCLEGQMTMWTDGQEIQLNPGDF
                     LHVPANTVHSYRLDSHYTKMVGVLVPGLFEPFFRTLGDPYEGHIFPCEPQALRFDRILQ
                     NIEALDLKVMKP"
     CDS             complement(10052..10627)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 63.1; E-value: 7.5e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg61_11"
                     /transl_table=11
                     /translation="MTSRGDSREKILHTASRLFQLQGYHATGLNQIVKESGAPKGSLYH
                     FFPNGKEELAIEAVTYTGKIVEHLIQQSMDESSDPVEAIQLFIKKTASQFDNTESIKGI
                     PVGLLASETALISEPLRTVCMKVFKSWEAVFARKLMENGFAEEEANQLGTLINSMIEGG
                     IMLSLTNKDKTPLLLIAEQIPVLVRKKG"
ORIGIN
        1 agaaacctcg cctttttgaa ttgcgccgcg ctgtagcagc tggcggtcat taatcttatc
       61 caaaacgatt aacgtttgag gctatcacgc caacttgata aggaggatgc tgaagatgat
      121 tacggctgaa gaatgcagaa cgtacaaaga atttgttgat ctttaccaat cctatcttta
      181 ccccttgctt ggcgccagac tgtcccggat gtattccccc aaaaacaaag tcattatcga
      241 tatgggcaca ggtccaggtt atttaagcat tcagttggct aaaagaacaa atgcgcacgt
      301 gcatgctgtc gatattaacc cggccatgca tgaaatcgct caagaagaag ctaaaaaaag
      361 cggagtaagc agcctgattt catttgattt ggaagatgtc caccatttat cttacgctga
      421 ccaatatgct gacttcatcg tctcctactc ttgcctgcat cattgggaag acgttgttaa
      481 aggacttaaa gagtgctata gagttctggc tccgggcgga aaaattgtca ttttggatac
      541 atttaatccc caaggaagcc atttagagat tatgcgaaaa caaatcaaag aaccggaata
      601 cttcaggttt gtaagagagg catttgaaga aagttattcc tttgaagaca ttcaccagtt
      661 tgttcaggat gccggcattc ccaattattc attagaaacc tttcactttt taccggagga
      721 ttttatagaa agcttagatg agctggagga tgctcccctg tgggaacaaa atgatcaaag
      781 tactgatcat gaaattgagt ctgtcacatg gatgttaacg atagaaaaag aaaaggaagg
      841 tgcattgtaa tgatcaatga atcaactgtt ttatccaaaa atccagaaat gccatcaaga
      901 aaatatttga aaagcattat tatagagccg ggcatcactt taaatgaaat ggcatcagat
      961 atttataacc atatcgacgg caaggtcagc atacatgata tttgctcaaa aatcgtcaat
     1021 gaatatgatg ttgattatca aacctgctta gaagattgta tggagctgtt tgagttgctt
     1081 attgatcatg aagcaatcaa agttaagcag ggggcatgag aattggaaaa acaaaaagtg
     1141 cttgctttac cagacgatgt acatgagctg agtacacacc gttctaaatc aatcgtaaat
     1201 tacatcatca ctctgcttgc ctttgccaaa aaacaaggat tgactcatca agatattgta
     1261 agctggattc acgagcaata tgaggaaaga ggatattatg atgagtggag acacattaac
     1321 agccaacaac cagttggatc atttgtggaa ctctttataa aaggaagacg tttactttat
     1381 gacaaaattg aattgtttga aacagaagat aaatatgtcg taaataccca cacttggtat
     1441 gaaaaagaac ctagtgaggc ctttttttat tttgaaattg atcccgaaga attttctgcg
     1501 tacgcttcca ttctcgcaat cgaaaacgca aaacgtctcg gaattaaaat cgatattgta
     1561 aaagaaacag atgtagagac agcttatatc tataaacatc aataacgcta ttgggaggga
     1621 gacatatgtg cgggctcgcg ggtattataa atctggctgc tccccgttct caggaatgta
     1681 cctttcatat attgaaaggc atggcagatg ccatcagcta taggggaccg gatgatgaac
     1741 aatatcatat tgattccaaa gtcggctttg catttcggcg attgtccatt cttgaccttg
     1801 taaatggaca gcagcccttt ttaaatgagg atggatcaat cgtcgttatg gtaaatggag
     1861 aaatttataa ctataaagaa ctgaaggctt ctttacacaa tcatatgttt aaaacgacat
     1921 ctgattgtga agtaattgtt catttatatg aagaaaaagg gattggattt gtagacgaca
     1981 tcatcggaat gttttcaata gccatttggg acaaaaataa aaacaaagta tttttagttc
     2041 gtgaccgctt tgggattaaa ccgctttttt acacagagct aaaacacgag cttatatttg
     2101 cctctgaaat aaaatcccta ttttctcatc ctcactgtcc ccgccaattt aattggaaag
     2161 aagcactctc agacatttgg ctaagcgggg aagcagccag taatcataaa gaaaccactt
     2221 ccttttttgt aaacatccaa aatctcgatg ctggccatta tctcgaaatt aatttgacaa
     2281 caaatgaacg aaaaacagca agctattggt ctttacagga tattttgctc aggcaaggct
     2341 atcgtgagaa tctccatccc gatgacctga ttgaaggata tagagaactg ctggcagatt
     2401 cagtccatag atgtttacaa agcgacgttg aagtcgggtt gtttcttagc ggtggcattg
     2461 attcagctgc agtcgcacat tttgctgcag aaaaacagga tctccatacg tttacagtat
     2521 taagccaaag tacatttaca aatgaagatg caaaatatgc ccattggctg gctaaagatt
     2581 tacaccttcc aaatcatcag gttctctatc aattagggaa cgatgagtta ttacaaccag
     2641 agtcatataa acatttgtta tggatctgtg aaacaccgtt ttgcggaccg gaacaattat
     2701 ataagtttca tttacataag tatgccaaag cgataaggcc aaacctgaaa gtcatgctga
     2761 ccggccaggg cagcgacgaa tttaacggcg gttacagcac gacactttca ccagccgaga
     2821 acccaagttg ggaaggattt attgaatcgg tcaatacgat ggagatgaac cggctgcatc
     2881 ggctgcaggg aaatatcttt agagtgtggg aggagcattt tggactttct cctataaacc
     2941 tttcttattt aaagagcaat gattccagcc aagcagatcc ttggcaatcg tatgtcctga
     3001 caaaataccg tgatctgcaa atgtataatt gctggcatga agatcggatc gccgcggcta
     3061 atcatatcga aaaccgtgta ccgttcttgg accatcggct tgttgaatgg gtttgcggaa
     3121 tacctgatgg actccgtaaa gacttgttat gggataagtc ggtattgcga aaatcattaa
     3181 caaatgagct gcatacaagc tatacccacc ggccaaaggt tccttttttc tatggtaagg
     3241 acgtgagata tacacataaa atgatgtttc atcttctgaa gaaaaacaat tatcagctta
     3301 tagaggaggc cttctctcac agcgatgcct ccagcataat acaggttgaa cacattcatg
     3361 ccatcatgac atatttggag gatgatcctg agtttacaaa ttttgaattt ttattaagac
     3421 tggtgaacat gggactttta tcaaaaatga ctaaagaaac cccttctgtt caattagaca
     3481 taaccagcca tttagaatcg ataacaataa aagactggca ctcacaggaa ggtgatattg
     3541 ccagtcgttt aaatatctca gccaataagt gtgaaggaca agatattttg gcgctaaacc
     3601 ctggcgtcac tctgttaagg ccggaaagcg atagtgagca ttgcatctac attgcggaag
     3661 aaggatttat tcagtttatt gtttcggagg aagacgtcgg agcttggctg catattctct
     3721 gcgatattaa tggaaaagac acacttcata cgattttaga cagacatggt gtcagccttg
     3781 aagaagtggc caaatatatt caagaagcca tcgaacacaa tatcattttg atcaaacaaa
     3841 aaaatctgcc agaaggagca tatagatgag catcttttat tcgttttccg cacttagggg
     3901 attagcaatg gggatttttt cgcctatttg gattctttat ctgatatcta aagattatga
     3961 tttccttcag attggattaa tgggagcggt acttgaaatt gctaagctta tatttgaagt
     4021 tccttccggc gtttttgctg atcgttatgg aattaaaatt tcaattgcca gttcattctt
     4081 tttctccatc cttacatggg ccttcttccc ttttatcgat tcagctgcta tttgcatact
     4141 ggctatgatc atatgggctt tatcagattc cttaatttcc ggttcttttg aaacttggat
     4201 gagccgtgtc gcaggggaag atcgattcgg caaagaaatg atgaaaaaca cacaattgct
     4261 aatcactttt ttaattattg gaagtattgc cagcgggtat ttgtattcat taaatatcta
     4321 ttttcctttc ctgctcgtta tggtgatcta cttattacta tttatttgga tgtctgtatt
     4381 tattaaagtc ccttctgttt ccgaaacaaa tcatggggat cagaaccaac atgattcgat
     4441 aaagattatc aaagaaagtt taaaaattat ctttaacaaa aaaagggttc ttttaatcgt
     4501 catagccggt ttctttacag ccacagccta tgacacaatt tcccgttact ggcagccttt
     4561 tttgagtgat ttaggctttt cagaaaagtc actgggatat atttttgccc tagaagggtt
     4621 taccgctctc gttcttttga cattaaccat caggttcgaa aagaagatcg aaaaaaatcc
     4681 atatctcgct ttaacctcat tggattccat gggcatggtc atgacttttc tattgtctag
     4741 agcattcagg ccgctgggca ttccatgtac agcgtttttg cttgcaattg aagatattca
     4801 tcatccgatc gtaacaagtt acttaaataa gtttttcccc gattcataca agaacacact
     4861 tttctcgtta aactcagggg taggagcaat tggagaaatt ctttccggtg tcattttcgg
     4921 catcatttcc gcagcctttg ggctctctgc catgtttgtt gttgtagctg tatttctatt
     4981 aatccctatt atcctttata cgatagtgcc taagattaaa gacaatgata tgaaagttca
     5041 gattgaaaaa tcccagcaag tgtaaatgtt ttgtatcaca gtaagaagac cttcttatta
     5101 aaagaaggtc ttctgctatt ctattcagtt atttcccaaa agccatcagc ttcgtataac
     5161 ttccaatata aagtgttccg tcctcagcga gctgaggaga agacacgacg ttgctgtcgg
     5221 tttgatagct ccataattca ttgccgtttg cgtctgccgc ataaaccttc atatcatctg
     5281 acccgaaata aaccgttccc ttcgcgtcaa tcagcggcgc cgttctgaca gggccgtctg
     5341 tgtagaatga ccagttcata tccccgtttt tgctgatgga aaacagctcg ccgcttcctg
     5401 agccgatgta gatattgcca ttatgatcaa tcgcaggaga tgagctggag aacccgttta
     5461 gcgggaatgt ccatttcaaa ctgcctgttg atgtataagc atacagctgt ccatcttggt
     5521 tgccggcata aatgtttccg tccttatcaa tcaccggata tcctttaaac gcatttgacg
     5581 tcgttctgga ccatttcacc tgtccggttc cggagttgat cgcataaaac acgtaattat
     5641 atgtgccgac atacacggtg ccgtttttgg caagcaccgg cacagagctg acgaccccat
     5701 ttgttttcaa cttccagcgc tctgtccagg ttgattttga cgtcggtttg atcgcgtgaa
     5761 cataattatc aagtgttgag aaatacaacg tcccgtctga accgatcacc gtttcagagc
     5821 ttggcccgcc gcttaacgga accgttgtta aaatttctcc cgtttctttg tcaataaaat
     5881 aaatcttttt gtcataggat gccaaataga taacgccgtt ggtcccaagt acaggagatt
     5941 gcgtatatgt ttttccaaga ttgcccgtca cccatttgac tgagccgtct ggattaaagg
     6001 ctttcatttc cccgtctctg gaatgaagat atactgtgcc gtctccgtca atcacagccc
     6061 ccgctccatt ttgcggagtc gttctgatgt cgttttgcca tttcagcgtc ccgtctgtat
     6121 ttccggcgaa ccggctttcg cgtgaccagt taaacatggc aggcgccatc gcttgtacat
     6181 catatcttcc tggcaaaaag ccagatgctc cattattttg agaaaacacc gtttccgccg
     6241 cataagcagc tgtcggctga agcactttgg cagcgggcac atcagaaaca gcgccggccg
     6301 aaacagccgc cgccaccgca gctcccgcaa tcaaagcttt catacgaaat gacttgacca
     6361 tcattgagac ccccattata tgtaacttct aatttgtgac catcataaca tattcatcca
     6421 ttttataaat ctatttcaca aaaacatcac aaactagaaa actatgtaag agtattcacg
     6481 gacgtttttt cagcacccga tcgaaatgca gccacaaacc aaatgacgtt gacagcagcc
     6541 gcagcgagac taactcccaa aacaaagatc acctcagaaa gcagatggtc actaaagaaa
     6601 ctaaacatca agataaaacc ggccgaagac aaatgaatca aaagcccgaa gccgcaaagc
     6661 accgccatga catacctcat tgcatcgact ccgagcatat aaacgagaaa tggaatgaaa
     6721 tacaagacaa ggatcatacc gacagctgac cacatgccag ctgaattaaa ctgattggcc
     6781 gccgctcccg ttccggccag cggcgaaagt gaagccgcca caatcacggc gcaaaaaaga
     6841 aacgcagaaa tggttgtcat gatcgccacg ctattttttt ttgacatcaa actcctcctt
     6901 taatagaaat attaaccttt tttattataa gtaagttgaa tgttatattc attatatttt
     6961 taaaaaattc cagaatacat acacaaatgc tatgcttctt tctagtatat ttatatagta
     7021 aaaaacaaag gataaaagac tcatttttct gtaatatcag gattttatca ccataccata
     7081 ttgcatgtac atgtttttca aagtatacta ttccagatta attcagagga gagagaaaaa
     7141 tacatggaaa aaccagcagg attttggatt cgttttttag cttattttat tgacggcatt
     7201 attgtatctg ttcctagtta tattattcta tttattatca attctgtgtt tgtagctggg
     7261 gctgtggcaa caaaccctta catgacggaa gaagagtatt tagtgaaata catgacgctt
     7321 gcatttttgc ctactatgct gatcatgatc gtcatcagcg tgttatatta cgggctgctc
     7381 acagcttcta aaatgcaagg cacacttggc aaaaaaattc ttggcttgaa agtggtcaat
     7441 gaacaaggtg aacgggtttc tgtcggacag ggaattggcc gttactttgc ctatatctta
     7501 tctggaatca tcttttatat cgggtttatc atgatcgcct ttggagagaa aaaaggcctg
     7561 catgacatca tttgcaaaac acgtgtcgtg tataaataat agaaaaaagt ctagacgcca
     7621 ataggcatct agacttttgt tttctttgca ataggctgcc acgacagata cgtagcgctt
     7681 ctccacaacc actcaaacgg ccccatccga aagacacgaa gccaaaggtg gctgaagacc
     7741 atttgaacgg cacaaacagc aattgtaatg agcacaccgg cagcagggta cacttttcca
     7801 tacaggccca agccgtaatg ataaaaaatc caagtacaca caatagactg catcaaataa
     7861 ttggtaaatg ccatcctccc aacagcggag aatgattgca gcactgttct cactcttgtt
     7921 ttatgataaa gatagacaac cgttgtaaca tagaaaaaca tgaggaaagg cgcgccaatc
     7981 agcaaacata tttctttatc cgttacactg tacagcacct gggcgccgat gccgatgaca
     8041 agcccagcca tccataatcg ttttaatcct ttgcgatgct tttccggttc atgcaaatac
     8101 cgtgattttg ctgccgcagc tcccagcaaa aacatgctga aatatggaat ggatgcaaag
     8161 aagtagttga gcggattata cgtaagcatg ccattcgaag acatgtaaac aagacggtcg
     8221 tggatccgct gttctgcaat atccttcagg ctgccgcttc cataaacatg aatcgcttgt
     8281 tttgcctgct gtgttaccgc ttgtacccat tcctgtccgt ttgattgatc aaaacttgtc
     8341 aacatgaacg gaatggaaaa cagaagatac aaagagaccg cccatatcag cagtgttttc
     8401 ggctttgctt ttcgaaacaa gagcaggaca aatccgagca gggcatattc tgttaaaata
     8461 tccccgtccc atatcaaaaa ggcatgaatc gttccaaaca agagaagcgc cattaacctt
     8521 ctcacatata acggaacaaa ccgtttccct ttgttttctg ctctctccat catgacaacc
     8581 atgccaaatc caaataaaaa ggaaaacaat aaaatacatt ttgtttgaat gaagaatttc
     8641 agtatgtctg cggcggcaaa atcagcttca gaccacttat ccatgaaaaa attctctttt
     8701 ccaagcatag acaaatacat atccggataa ctgaaatgtg ccagattgac aaataagatg
     8761 ccgaaaatcg ccattcctct cagcacatca agcacaccga tccgctcatt tgttaaagtc
     8821 ggctgtaatg aagacatagc catcacgctc cttttttctg taccttaagg gtaggaaaaa
     8881 atgaagcgcg gtaacatcga tttaggtgtc aggccggcat gaaaacctta caatcttgtc
     8941 atctttatgg tttcatcacc tttaaatcta atgcttcgat attctgcaaa atgcgatcaa
     9001 agcgcaaagc ctgaggctca catgggaaga tgtggccttc atacgggtcg cctaacgtcc
     9061 ggaaaaacgg ttcaaataaa ccaggaacca atacgcccac catctttgta tagtgagaat
     9121 caaggcgata ggagtgaacg gtatttgcag ggacatgcag gaaatctccc ggattcagct
     9181 gaatttcctg gccatctgtc cacatcgtca tctggccttc aaggcaataa aatgtttctg
     9241 tatgatattc atggtagtga tcaacgattc ggtcaccttt agggccttca gatgatacga
     9301 cgataaactg gccatctgta tttttttgtg cagccacaat gcggtgaagc tgatctccag
     9361 tcaacagacg atctccttct ccagattcaa gaacgtatgg aaccgctcca tctggcagct
     9421 ctgtaagttc cgctaatttg gccgaacatg caggctttgc ttcatctaga aatacaatgt
     9481 ccgctacagc ggctgcttct gcaaatcgct cgtttgagac ttcttcgctt gcgtacggcg
     9541 gatgttcagc gtgatcatac ggattcccaa taacggaata caagtgcgct acgtttcctt
     9601 tcatcgtgta agacaccagt cttgttctgt ggctctgcat ccggtagctg tgcggtgttc
     9661 ccgccggaat gttggcataa tcacctgata ttaataaata gcgttcacca tcaagtgtca
     9721 gttccagttt cccgtccaaa acgagaattc cttcatgtgt gtccttgtgg acgtgaagcg
     9781 gaaaggcatc tccttttccc ccggaaagaa gcacgatctc aaacaaatca cctgtgctcc
     9841 tcccattcgc catcaccgtg gcaacctgtc tgccgaacag atagcgctcg ccttctccgc
     9901 tccggagcaa ataaggcatt ttttctttag gcaatgaatg tgtacataat gttttcatat
     9961 tatcgcttcc tccaatttag accagtctat atattatcat tcatttgtct agaccgttct
    10021 atataattgt aggagaaagg ataacaaaat gctacccttt ttttctcacc agcactggta
    10081 tttgttcggc aatgagaaga agaggcgttt tgtctttatt cgttaacgaa agcatgatgc
    10141 cgccctcaat catcgaatta atcagcgttc caagctgatt tgcttcttct tctgcaaatc
    10201 cgttttccat taattttctg gcaaaaaccg cttcccagct tttaaacacc ttcatgcaaa
    10261 ccgtccgcag cggttcactg attaacgctg tctcactcgc cagcaaaccg actggaatac
    10321 ctttaatgct ttctgtgttg tcaaattggc tggctgtttt tttgataaaa agctgaatcg
    10381 cttcaacagg atcagaggat tcatccatgc tttgctgtat cagatgttca acgatcttac
    10441 ctgtatatgt aaccgcttca attgctagtt cttctttgcc attcggaaaa aagtgataaa
    10501 gcgatccttt tggagcaccg ctttctttta caatctggtt caaacctgtc gcgtgatatc
    10561 cttgcagctg gaacagacgt gacgccgtgt gaaggatttt ttcacgtgaa tctcctctgc
    10621 tagtcattaa aacattccct cctaggtatg gtagagcgac ttatataata taaaaaagaa
    10681 ccctgtgatt gtcaaaaggg gtaagaccct tccggatggg gtaatgtaca aaaacagcgt
    10741 ctaggaggga tctctcaatg acaatcgatc attcagtcac aaatacagag cagcttgaac
    10801 aacagaaccc cgccataaaa acaaagctca aactgaaaaa gcttaaggat caggtgatcg
    10861 tcattaccgg cgcttcaagc ggtatcggac ttgtcacggc gagaatggca gctgaaaaag
    10921 gcgcaaaggt cgtggcagca gcgcgaaatg aagaggcgct gaaggagctc actgatgaac
    10981 ttaaggaaaa agggcacgac gccatatggg taaaggcgga tgtcggaaaa gaagaggacg
    11041 tcaaccgcat cgcagaaacc gcgatcagca cattcggccg ctttgataca tgggtcaaca
    11101 atgcggccgt ctcgacttt
//
