LOCUS       gnlProkkaMLEOMEED_12    2768 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MLEOMEED_12.
ACCESSION   gnlProkkaMLEOMEED_12
VERSION     gnlProkkaMLEOMEED_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 11:07:46
            Original ID  :: gnl|Prokka|MLEOMEED_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2768
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2768
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[93:2766]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      94..2766
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2768
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2768
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             94..2766
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     2.9e-92. Score: 301.0. Matches aSDomain:
                     nrpspksdomains_ctg11_1_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-864). E-value:
                     7.9e-113. Score: 369.0. Matches aSDomain:
                     nrpspksdomains_ctg11_1_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     241.4; E-value: 3.5e-73)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_1"
                     /sec_met_domain="Condensation (E-value: 1.5e-79, bitscore:
                     253.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2e-125, bitscore:
                     404.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTL
                     EGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQA
                     SIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDP
                     LPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSAS
                     RDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKD
                     LHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQN
                     TLFSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAF
                     TLHGLFERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSER
                     SPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLE
                     VDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFP
                     LSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAIHQENVTTAH
                     FIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTE
                     ATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVAR
                     GYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPG
                     EIEAALRSIEGVREAAVTVR"
     aSDomain        103..993
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_1_Condensation_Starter.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="2.90E-92"
                     /label="ctg11_1_Condensation_Starter.1"
                     /locus_tag="ctg11_1"
                     /protein_end="300"
                     /protein_start="3"
                     /score="301.0"
                     /tool="antismash"
                     /translation="HTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIP
                     FKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPD
                     QPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDT
                     IILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     aSModule        103..2685
                     /domains="nrpspksdomains_ctg11_1_Condensation_Starter.1"
                     /domains="nrpspksdomains_ctg11_1_AMP-binding.1"
                     /incomplete
                     /locus_tags="ctg11_1"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       172..288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0001"
                     /evalue="2.30E-08"
                     /label="C2_starter_024-063"
                     /locus_tag="ctg11_1"
                     /protein_end="65"
                     /protein_start="26"
                     /score="26.7"
                     /tool="antismash"
                     /translation="ICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLE"
     CDS_motif       493..558
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0002"
                     /evalue="9.10E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="ctg11_1"
                     /protein_end="155"
                     /protein_start="133"
                     /score="25.0"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNVMGNQIIDLY"
     CDS_motif       892..981
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0003"
                     /evalue="1.20E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="ctg11_1"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.4"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       1033..1146
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0004"
                     /evalue="4.40E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ctg11_1"
                     /protein_end="351"
                     /protein_start="313"
                     /score="28.9"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQY"
     aSDomain        1483..2685
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg11_1_AMP-binding.1"
                     /evalue="7.90E-113"
                     /label="ctg11_1_AMP-binding.1"
                     /locus_tag="ctg11_1"
                     /protein_end="864"
                     /protein_start="463"
                     /score="369.0"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FERQAAFTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNE
                     SIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSA
                     PNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSF
                     LTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAI
                     HQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVK
                     IR"
     CDS_motif       1669..1710
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0005"
                     /evalue="5.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg11_1"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       1894..1953
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0006"
                     /evalue="3.70E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg11_1"
                     /protein_end="620"
                     /protein_start="600"
                     /score="34.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       2479..2568
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0007"
                     /evalue="5.20E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg11_1"
                     /protein_end="825"
                     /protein_start="795"
                     /score="57.1"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       2650..2715
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg11_1_0008"
                     /evalue="4.80E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg11_1"
                     /protein_end="874"
                     /protein_start="852"
                     /score="40.9"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
ORIGIN
        1 ggattatata gtcatataat ttcttttatt gtcatttttc tgcttttttc tacattttct
       61 tatcctctta ttatgagaac tggagggaat ccgttgagcg aacatactta ttctttaacc
      121 catgcccaaa ggagagtgtg gtttaccgaa ctgctggagc cagataccag catttgcaat
      181 cttacagctt gtgtgaaatt taaaggcaat attgagcttg atactctgga gggagcactg
      241 aatcattcca tctcccgcaa cgacgccatt agatttcagc tgttagaagg agaagagctt
      301 gagcctcgat tgcaccttac tgaatataaa tattatccac ttagaataat tgatttttca
      361 aatgttgaaa tgatagaaat agagcaatgg attcaggatc aagcgagcat tccatttaaa
      421 ctgttcaact cgcctctttt tcaattttac ctccttagaa ttgactctca tgaagtttgg
      481 ctatttgcga aattccatca tatcataatg gatggaatct ctttaaatgt gatgggaaat
      541 caaattatag atctttatca aaaaatgaaa aagaaagatc ctttacctga tcagccggaa
      601 ccttcttact tgagctacat cgaaaaagag agtcaatatc tacaatctcc acggtttgca
      661 aaggaccgtt tattttggac gcaaaccttt gagcacccgt tggaatacca ctcgttagcc
      721 gaccagacgt ccttacaaaa acagagcaca tctgcatcca gagacaccat cattctttca
      781 cctgatctag agcaaacgat tcgaatcttc tgcgaagaac acaagatcaa tatcatttcc
      841 ttatttatgg cttcatttta catatgcatc agccgaatca cttctaaaaa agatcttgcc
      901 attggcacct actatggcaa cagaggttca aaggctgaaa aagaaatgct cggcatgttc
      961 gttagttccc ttccaatcag aataacggtt gatcctgaca cagattttct ttcctttgtc
     1021 cgcacaatag gcagggaaca gctttctgtt atgcgtcatc aacggtttcc ttataatttg
     1081 cttgtaaatg aattaagaaa tgaacagaag gatttacaca accttatcgg tatatctatg
     1141 cagtatcagc cacttcagtg gcacaatgca gatgattttg actatgaaac agcgctttat
     1201 ttcagcggat acaccgcgaa cgaactttca gttcaaatac aagaacggat agacaatgga
     1261 accattcaat taaatttcga ctatcaaaat accttgtttt ctcttgagga tattaaacga
     1321 atacaatctc atctgcttac catactggaa aacgccctta aacatccgca cagctttata
     1381 agagaattag atatgacgaa tacaagagaa aagcaaaaat tgttgtatga gtttaacaag
     1441 acggaagctg tttcgcctaa agctttcacc ctgcatgggc tgtttgagcg acaggcagct
     1501 ttcacaccgg agcggctggc cattcgcttt tcaggcggtt cgctgacata cgctgagctt
     1561 gatatgtacg ccagccggct ggctgcgcac cttgcggcac gcggcgtcac aaacgaaagt
     1621 atcgtcggtg tcctgtctga acgctcacct gacatgctga tcgctgtcct tgctgtattg
     1681 aaggccggcg gggcgtattt gccgcttgat cctgcgtatc caaaggagcg gctgagctac
     1741 atgctgaaag acagcggggc atcgctcttg ctgacacagc cgggatgctc cgcaccaaac
     1801 ttttctggcg aaacgcttga agtggacatg acatctcttg cgagcgaaaa agcagaaaac
     1861 catgagttta ctcctgctga cggcggatct ctcgcctatg tcatctatac atcgggctct
     1921 accgggcagc cgaaaggagt ggccgttgag caccgtcagg ctgtttcctt tctgaccggc
     1981 atgcagcacc agtttccgct ttcggaagat gacattgtca tggtgaaaac ctctttttcc
     2041 tttgatgcgt ctgtgtggca gctgttttgg tggtcgcttt ccggtgcttc ggcgtatctg
     2101 cttccgcccg gctgggagaa agactccgca ttgatcgtac aagccattca tcaggaaaac
     2161 gtgacaacgg ctcattttat tccggctatg ctgaacagct ttctcgatca agcggaaatc
     2221 gaaaggctga gtgacaggac aagcctaaag cgtgtattcg ccggaggtga accgcttgcg
     2281 ccgcgtacgg cagcccgttt tgcttctgta ttgccgcagg tatcattaat ccatggttac
     2341 gggccgacag aagcaacggt agacgcggca ttttacgtat tggatccaga acgggacagg
     2401 gatcgtttgc ggattccgat tgggaagccc gtacctggtg cgcgtttgta tgttttagat
     2461 ccgcatttag ccgtacagcc ttccggtgtc gccggcgaac tgtacattgc cggagcgggt
     2521 gttgccagag gttatttgaa tcggccggca ttaacggagg agcgttttct tgaagacccg
     2581 ttttacccgg gggaacgcat gtacaaaacc ggggatgtgg cgcgctggct ccctgacggg
     2641 aatgttgaat tcctcgggcg cacggatgat caggtaaaaa tccgcggcta ccggattgag
     2701 ccgggagaaa ttgaagcggc actaagaagc atagaaggcg taagagaggc ggctgttacc
     2761 gtacggac
//
