LOCUS       c00022_gnlPro..        15614 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GMNLNDML_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 12:50:06
            Original ID  :: gnl|Prokka|GMNLNDML_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15614
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15614
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2497:5614]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2498..5614
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15614
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15614
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             408..923
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACVRSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1091..2080)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MRMLEKIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARFLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2498..4756
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="Gly_radical (E-value: 9e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.5e-245, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             4793..5614
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-26, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             complement(5837..6148)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 65.4; E-value: 1.3e-20)"
                     /gene_kind="other"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="FeS_assembly_P (E-value: 7.9e-20,
                     bitscore: 65.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAEGTAEIT
                     MTLTIAGCPLTEWLAKNIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARMELGIHS"
     CDS             7208..8128
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8298..8822
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTPNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(8917..9162)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_8"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00078, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRPDK"
     CDS             9335..9763
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(9866..10507)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 9.4e-19, bitscore:
                     63.0, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAVRYQAIPEDADFIAVFGGVNDYGRDQPLGQYGDCDMTTFYGA
                     LMMLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(11523..13190)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 410.4; E-value: 2.8e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_11"
                     /sec_met_domain="BCCT (E-value: 1.7e-124, bitscore: 410.4,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 gcaaatgttt tgctcttgat tcaaaatcaa gagaccctac acatttgatt cgtcgaaact
       61 ttgttcagtt ttcaaagatc taatcccgtg tgttaatcgc ttaacacaac ttaatcatca
      121 taacatctta atcaatatct tgtcaacaac tttttttaag aagtaacttg attaatttgt
      181 cacagttgcc gttgcgacaa cagaaactat cttaccaatt actgaagaaa ttgtcaacaa
      241 ctaatttcaa taattatttg gtggtgagat gcatctgccg tagcagcaac gtttactaat
      301 ataccaattg aagtaaaaag tgtcaacact ttttctgaat ttctttttat taatagtcaa
      361 accagctttc tttctctata ctatttaatt aaaggagcga ctaaattatg ctagcttggc
      421 taccattctt tttgatttca ttaatgttta ttgttctact atacgcttgt gtgcgatcag
      481 cgcgcacaaa tatccagcgt tttaagcaac tcagtttaat tgcctttctc tgggtcttaa
      541 ctgctttttg ctatacacct accagttaca attttggtac ccaactcgtt attcaatata
      601 ttcaatgggg acccgttaag ctgaacgtga ttcctttcca acaacttgac attgaatttt
      661 ggctcaacgt tctcctcact gttccattgg gcggtttact ggcatggaat tttcccgact
      721 tgccttggcg tcgttttatt tggttgggat ttcttacggg gctaacactc gagctgggac
      781 aattcatcct tgactggttg gttaacctca aacgttgggt tgatatcgat gatgtcatca
      841 caaattgggc tggtgtcatt atcggtgccg ctggttataa aattgcacgt catgttcccg
      901 gacttcgctg gttgcaaaaa taacgtatat atagaagcaa aaagcaaaac aacgtttgtt
      961 tagcacccac aagtgccaaa cacttcagcg ctctagctgt tatgaaatcg taattaaata
     1021 agcgtcgcag ccacttaagg ttgcgacgct tatttaattt aactactaac tattaatgaa
     1081 gctgccatca tcaggattca aaaaacagat cgaatactcg cttacgatct tggttccaga
     1141 cttgattgtc actagttgga taaactcgat ttgttaacac aaccagccca atttgacgat
     1201 ccaaatcaaa agcaactgcc gggccagtaa aaccagtatg gaaatattga tgtcgtcccg
     1261 cacgtcgttc ccaacctaac gtccggccat tttcgtcata ctcgcctaac cagtcaaaga
     1321 cattttcatc cagcacccgt ttgccttgat attcaccaaa gtttaacatc atttcaataa
     1381 atacggataa atccgtcagc gttgagaaca agcctgcgtg accactctca ccattcaaca
     1441 aaaaggcttt ataatcatgc acctgtcctt gaatctgacc ccgccgcgga tcaaactccg
     1501 tcggcacaaa ccgaatcttc ggacgattta agttataacc cgtattggtc atcgctagtg
     1561 gatagcaaac gtggtcttga atactccgag ccaatgagcc gtcaaccgca cgaataatcc
     1621 atcccaataa aataaatccc aggtctgaat agacatacgt tgtccctggc gccgtgacga
     1681 gtggcgcatc ataaaccgct ttgatcagat cttcacgttg catcttatcc aggttatcaa
     1741 tatctgccgg tagcccacta ttatgaagta acaagttttt aatcgttatt tcaggatgag
     1801 tgaacccagg taaaaaccgg gcaaccgagt ccgttaaatg aatcgtgtgg tccgataaca
     1861 actgaaagat cctcgtcgtg gtccctacaa ccttagttac cgatgctagg tcataaatca
     1921 tcgcaggatc taagcccacg gcaaactcat cgcggccctg cttaccatga tagtattgat
     1981 tgataccttt aggggtgatc aagctaaacg acgccccata aatgtcgcca gcttcaatac
     2041 aactgtcaat atattgttca attttttcga gcatccgcat tacgcccacc tttcactaca
     2101 ttcactagtt tctgcttatc ttctttatga taacgaactt cctcataaaa tcaacggcaa
     2161 acgcttttaa caccctccac acctcgttgc actttttatt aattaactag ttaaacactt
     2221 gttacattat ggacaatatt ccacttatat atcaaaacaa gtcttgtttt tagccgtttt
     2281 ctaaatataa ttaagtgaat taccaatgcc tatctagcta tgtaagtact gttatatcaa
     2341 cgttaatagt caacttttca ataatagatt gcaaaaaaat aacccaaacg tgaaataaat
     2401 cacctgaaag cggttacaaa tccagcaaaa aatgttatga ttcaaatata gaatttcatc
     2461 aatcatttga ttggattcaa attatggagg cgagaaaatg attacatcag aaaagacaac
     2521 aaaaccagca gcttggaaag gtttcaaagg cgggcactgg caggaagaaa tcaacattcg
     2581 tgattttatt caaaataact tcacacagta caatggcgac gaaagcttcc tggccggacc
     2641 aacagccgct actaagacct tgaatgacaa agtcttagaa ttaaagaaac aagaacgtgc
     2701 cgctggtggt gtgttggatg ctgatactaa agtcgttgca acgattactt cacacggccc
     2761 tggttatatt caaaaagatc tcgaaaagat tgttggtctc cagactgaca agcctttgaa
     2821 gcgggccttc atgccatttg gtggtattcg aatggctgat gacgctttga aatcatacgg
     2881 ttatacccct gatgaagaaa acgacaagat tttcactgaa tatcgcaaga ctcataacca
     2941 aggcgtcttc gatgtttata ctcctgacat gcggaaagca cgtcactaca agatcatcac
     3001 cggactacca gatgcatacg cacgtggccg tctcattcct gatcttccac gggtcgctgt
     3061 ttatgggatc gatcgtttaa tggaagacaa agctaatgac tttgcccaca ttggtgatgg
     3121 tgaattgact gatgatgtta ttcgcctccg tgaagaagtt caagatcaat accgtgcttt
     3181 agcagatatg aagaagatgg ctgccagtta tggctacgat attagcaagc ctgcaactaa
     3241 tgctcaagaa gctattcaat ggatgtactt cgcttactta gctgctatca agacccaaaa
     3301 cggcgctgca atgtccgttg gccggattga tacaacgatg gacatcttca tccaacgtga
     3361 cttggacaat ggtgttctgg acgaaagcca agctcaagaa ttaattgatc aattcgtcat
     3421 gaaactacgg atggttcggt tcatccgtac tgaagaatac aattctctct tctctggtga
     3481 cccaatctgg gcaaccttat caatgtgtgg tttaggcgtc gacggtcaac accatgtgac
     3541 taagaccgct ttccggattt taaagacttt ggacaacatg ggcgccgcac cagaaccaaa
     3601 catcacgatt ttatggtcag atcgcttacc agaagacttc aaacgttacg caactgaagt
     3661 ttcaatcgac agttcaacca ttcagtatga aaatgatgac ttgatgcggg tacaatgggg
     3721 taccgattat tatggcattg cttgctgtgt ttccgcacaa ccaattgctg atggaatcca
     3781 gtacttcggt gcccgggcaa acttagccaa agcgattctt tatgccatca atggtggccg
     3841 cgacgaaatt gctggagatc aagttggccc tgcttacgaa ccaattactt cagaatacat
     3901 cgattacgac gaattcatga agaaattaga caagcaaatg gattggttag ctgacactta
     3961 cgttaactca ctgaatgcaa ttcattatat gcatgataag tactactatg aagctgccca
     4021 attagctttg aagaatactg atcttgatcg gacctttgca actgggattt ctggcttatc
     4081 acatgccgcg gattcaatct cagctatcaa gtatggtcac gttaaagtaa ttcgtgacga
     4141 acgtggtatc gccgttgact tcaaagccga caatgactac ccacgttatg ggaacaatga
     4201 cgatcgcgct gatgacattg ctaaatggtt agtcaaagaa ttatacagca agatgaacac
     4261 gcatcacctc tatcggaatg ccaaactttc aacttctgtt ttgacgatta cctccaacgt
     4321 tgtttatggt aagaacactg gtaccacacc aaatggccgt caaaaaggcg aaccattctc
     4381 accaggtgct aaccctgcat acggtgctga aaagagtggt gcattagctt cacttctttc
     4441 aactgccaaa ttaccatacc gttacgcaac tgacgggatt tccaacacgt tcggcgttac
     4501 ccctaacacg ttaggccatg acctcgaatc acggaaagac acgttagtaa acatgttaga
     4561 cggttacatg aagaacgatg ggatgcactt gaacatcaac gtcttcaata aagacacttt
     4621 gattgatgct cagaaacacc ctgaagaata cccaacatta acggttcggg tttctggcta
     4681 ctgtgtctac ttcgcagatt taaccaagga acaacaagat gacgttattt cacggacatt
     4741 cttcgaatca atgtaacatt taatctttaa tagttaagaa ggcgaaaggc tcatggaaaa
     4801 caaacaagtt tcaacaacgc aagcggcggc aaaggagcct ttgataggct acgttcactc
     4861 catcgaaacg tttggctccg ttgacggacc aggtatccgt tacgtggcat tccttcaagg
     4921 atgccacatg cgttgccaat actgtcacaa ccctgatact tggaaactca acgttggcga
     4981 tcaaatgacg gccgacgaga ttctcgaaga cgcggctaaa taccgggctt tctggggcaa
     5041 gacgggtggc atcacagtca gtggtggtga atcactggta caaatcgact tcatcttaga
     5101 cttattcgaa aaagccaagg cgatgaatat cagtacttgt ctggatacct ctggacagcc
     5161 ttttacccga gaacaacctt tctttgacaa gttcgaacgt ctaatgaagg tcacggacat
     5221 ttcgttggtc gacattaagc acatcgattc tgccaaacac aagcagttga cccagtatgg
     5281 gaacgaaaat atcttggata tgattcagta catggcccaa caccacgatg atatgtggat
     5341 tcgtcacgtc ctggttcccc aacggactga ttacgatgaa gacttgaaga aactcggcga
     5401 ttacattgct aagattccaa acgacgtcgt tcaaaaagtc gaagtattgc cgtaccatac
     5461 tttgggcgtt aaaaaatatc atgaaatgaa gatcaagtac cggcttgaag gaatcgagtc
     5521 tccaacccaa gatcgggtgg caaatgccga aaagctactg cacactgctg attacaacgg
     5581 gtacaagaca tggatgccat tgccaaaact ttaaatcggc atttctagca tgactaaaac
     5641 accagcgtta caatcgtcta cggatggttg tgtcactggt gtttttttgc tggctcgacg
     5701 catgcacgta ttgctggccg gaattagtac agtggcacgc aaaaaaggcg ccgcgagcaa
     5761 accagcaacg tctttcctta atcatgccct atccaatgac cgtcagccct tggactggct
     5821 gcgaacaggc cggccactaa ctatgaatgc ctagttccat tcgagcttcg cgggacatca
     5881 tactttcgtt ccaagcaggt tcccacacaa tctcaatctc gatattgtta acttctggta
     5941 atttgatcag ttcatcgtga atgttcttag ccaaccattc ggtcaaagga cagcccgcaa
     6001 tggtcaacgt catggtaatt tcagcggttc cttccgccgt caattgtgca tcatagatca
     6061 accctaagtt aactagatca attcctaatt cagggtcaat gacatgtcct agcgcctcga
     6121 aggcccggtc tttaaacgtt gttgtcatcg tatctcgtcc ttccatacca gcttgaattc
     6181 actgattaat cacgccaacg tttcgcggta taagtgccac cacacttgat acacgtcatc
     6241 gttatataaa gcgctttctt gtctacttct attgtaccgt atgtcagccc atattcaatc
     6301 aattattagc gctaattagc cgacttttca aacgatcggt caatcagcaa attatgcgac
     6361 tatttctcga aaaaatttac tataatcccc gatatagcag cgttttgagt cactattgat
     6421 ttttattgcg aattcgcggt tgtttttgtt gtaagcgttt gcggtttatg ctattatact
     6481 aagtgaggaa aggaattaat cctcgattag caaagcttct caaaagagtt tggctgtcgc
     6541 tgtaatgtta gacagctagt atcacagttt gggtcgttat cgaaaccgtt ttaagcgccg
     6601 tgaagcgtta tcggtctagc gagtgtcgtg agatttacgt tggatgactg aacgttgacc
     6661 cttagataaa cgataaccgc aaagaattaa ttggcattag aatgacgaac agattttaac
     6721 taagttttag ttggaaacag gtgtctccga tgaccagttg ttagttccac attaccagtt
     6781 ccatttgtag actcaggtat tacaaagttt aaacggaggt gcatgtctgt tacgaagaca
     6841 ttcccaagtt ttaaacgcga gtttgacttt cgttaaaacc cgtctaacga gttgcaatca
     6901 agtaacaacc ttactttaga tcgactatag cagatagtta caataaatac gggttagtcc
     6961 gttagaagtt ggacacgcgt aaaattgaat agcatgaagg tgtatcatat taacactgaa
     7021 caatttttca ttgctaatca ggattattcc tcataagtag aactcaagca gagaagcctt
     7081 gggttctatt tttttgctct aaaattagat ttaccaacag tcggcaccag acgtaaccgt
     7141 ttacatcctc ttacgaaaac cgtatactga atttaaatca agttgcacat tgaggaggac
     7201 tttagttttg aaaacgatta atttaggtca cagcaatatt caagcttcca gcgtggcgct
     7261 tggcatcatg cgcatggacg ccttggatgt cgctcaagcc accaaggtta tcgataccgc
     7321 tgctgattta ggcatcaatt acgttgattc agctgatatc tacggtggtg gtcaatcatc
     7381 gaccatcttc ggtcaagcac tcaagcaggc tcacgtatcg cgtgatcagc tctatattca
     7441 gtcaaaaggc ggcattgttc ctggcaagcg ttacgacttt tccaaacagc acatactggc
     7501 agccgtggat ggcgagcttc aacgcttagg tgttgattat ctcgacacct tcctcctcca
     7561 tcgaccggac gccctgatgg aacccgaaga agttgctgcc gcttttgaca agttgcaaac
     7621 tagcggcaag gtgcgccact ttggcgtctc taacttcaat cccatgcaag ttgacatgct
     7681 tcaagcggca ctaaaccaac ggctcatcat taaccaactc caatttggta tcatgcatac
     7741 cggtgcgatc gactttggct tgcacacgaa catgcaggac gaacgtagtc ttaaccacga
     7801 cggcgagatg atcgaatact cacggctcca taagatgacg attcaagctt ggtcgcctta
     7861 tcaatacggt aacttcgcgg gtatcttctt agacaatccg aagtttccag aacttaataa
     7921 tgccatgcaa gcactcgccg atgagaaaca ggtcactaaa tcagctattg cgaccgcatg
     7981 gattctccgg cacccagccc acttccaagt cgtccttggt acgatgaatc cggaacatct
     8041 agctcaaaat gctgctggag cagacgttac gctttctcgg caagaatggt acgacattta
     8101 ctttgcagct ggcaacgatt taccttaatc acgatcgacc taacagaatt gacgattagt
     8161 ttttacaatc aaaacgacga ccccaaatca ggattgattt tcaggtcgtc gttttttaga
     8221 cgtttcacta acatttttga tgtactcacc acatctacgc gtatacttaa tcttatcaag
     8281 actcaggagg cgagcgaatg acatccactt gcacgatctg tgaacgaatc aaactaattc
     8341 aggcacatca gaatccttat ttcgtttacg aactcacaac gggctacgtg gtccttgctg
     8401 atagccagta ctttgaaggc tacacgctct ttttagccaa acatcacgtt accgaattac
     8461 atcatttacc ggcacacgag aagttacgat accttgaaga gatgagtatc gtccaggaag
     8521 cttgtgcgca ggcctttcat gcagacaaaa tgaacattga actactcggg aatggtgacg
     8581 cgcatgttca ttggcactta tttcctcgcc ataacggtga tacgcccaac cccggtcccg
     8641 tctggtggac accgctggaa acaatttatg gtgatgatgt cagtctagac attccccgtt
     8701 taagccggtt gaagcgcacg ctcagcgtag caattgaggc cacgcttaat gctcgggaag
     8761 cagaattgca ggctttagag gcactcacaa ggcctgctag ccacagaatt gacagcaatt
     8821 agaccaaatc aggacccaga cccgcttaga tcttggtggc tacaccccaa ttcttaatcg
     8881 caatccgtca ccgtatttca aattgccaaa atccacctat ttatccggcc gactatcata
     8941 cgctcgctta gatttatagc cagctcgaaa aaccgtcttc ataacttcaa tgtgccgttc
     9001 cttagttgct tgtgccttag ttccaaaaat aaagcgggcc cattcgcgct gataaccagg
     9061 tgtcaaagcc acaaagaacg tttgcaattc agcatcaacc gctaacaatt cggttaccgc
     9121 cggaatattt ttttcaaatg aactgagggg tgctgtactc ataatcaaac ctccgattag
     9181 ttttacttaa atttactgta agaaagggaa aatccctaat tttcaggttt ttatatttcg
     9241 aattttcata aaattgcgct atcattatag tataagtatt attatttgac tactataatt
     9301 aaccatactg ctattcacca aggggagccc tgctatgcca aaatttgata tcaccctcat
     9361 cagtcccgaa cgcgctaaag cgatgttgac tgaatataaa gaacaacgta agaactctgt
     9421 cccacatctg gcccatcctg gccgctatat cttgccggat tacaaattaa ctcgtcgccg
     9481 ggccgcattc aaaattgtta aacatacctt tttaacgccc cactacaagt cttacgttgc
     9541 catggactct gacaacggcc acacactctg gtttcataat ttcggttccc taaccgaagc
     9601 tttattctgg ttagaaaccg gccttaaaat cagcgatacc gactcccatt ctaactacaa
     9661 ggaatggatg gctaagcaca ctacggaaat cgaaaccttc aaagacttgc tgcgcgagca
     9721 gaagcataaa caagggccca agactaagaa aaaagccaag tagcccgttt tgacacctag
     9781 attcagataa gcagcagtac gctcattagc gtgctgctgc ttttatttac gatcaactgt
     9841 gccattcatt actgactaga ccaacctaaa agtggctatc caaaaacgac tgcagcttgc
     9901 gtgcaatcac gcgatgaccg gcattgttcg gatgcaaagt atccaccgaa taaatggccg
     9961 cttgagcggg aatcgcaaat gtcattcccg catcacggta caagctcaaa tgtgggacgc
    10021 catagtctgc agtcatctgg gcaatcgctg cttcataatc tgactgacga tacccgagac
    10081 cattagtcac cgcactaaaa ctgcccccaa aatcagagcc aatatgaatt gctgaaataa
    10141 ataacttcgg cacggtcggc caattcgtct gtaatcccgt cagtaacatc attaacgcgc
    10201 cataaaatgt cgtcatatcg caatcaccgt attgccctaa cggctgatcc cgaccatagt
    10261 cattgacgcc cccaaagaca gcaataaaat cagcatcttc aggaatagct tgatagcgca
    10321 ccgccatcgc atcgtagcga ctcccaatcg ttgaaccaga gattcccaaa ttatcgctcc
    10381 gctcgacatc ccaatcagcc gccaaaatat catgataatg caccgtcgcc aacccattat
    10441 tcgccgtaat cgaatctccc aaccacgccg gccgcttaaa actaacatgc ccattactaa
    10501 tcgccatagc caatcctccc tttactatca tcgctatcat tctaatccat cccacctgaa
    10561 ttatggtaga aagatgcctt tatttaaagt caacagccac cagcttaggc ccgctggaaa
    10621 cagttccggt tagcgtaaac ctgcttagtt cgttcgtcct acgccgctct ccaggcattt
    10681 ctgccaattg ctggaacgcg gtggacacag atttaagtcg aagaccacgt cttaaatact
    10741 ggtcttctac taaccaagcc aaggacgctt gctaagtgga atttcaccgc tgagcattgg
    10801 ccgaaacgcc ttccattcgg gacagtattc gaatggtgga cgaagatata cccaactttt
    10861 gatgaatttg tcattgttct ccataaacag taattttatt aatcaactgt taggtcgaaa
    10921 agatattggg atagctcgct atttcggaat tactatagta ataatagaac acctcaacaa
    10981 agtggttagg gtaaccctaa cgtctcgttt aaagttccgg tatcaaaata gccaacgacc
    11041 aattgtgccg agttaagtgg ccgttcatca gccattcgag cggcttaccg aaacgtgttc
    11101 ggtgccacta aagtctgtgc ttgctatgcc aacggacaaa tgcccaaacc gcattaatcc
    11161 gttggctaga caatgctcgg cttcaacccg tggcttgaga ctggaggggc tgggtgacaa
    11221 tgctcagtag ccaaattatt cttagtcgga agtgatttcc ttccggctta gaataagact
    11281 cgtatttgag atgacgcggg ttatgcgtta gctcaaatcg atgtcggctg cgttccagca
    11341 attgtcaccc agccccggag gtcggaatag gacgctcacc ggctgacgaa cagaaaacca
    11401 accctaaaag gcatctttct accattattt caaacaggtg ggccaatctt aaaaggctcg
    11461 tattatggaa atccataata cgagcctagt ttaattgata tatttagttc aactgagtag
    11521 cgctaatcgg cttccgtttc acgtttccgt gcagtacgcc gttcgcgtgc gtagtcagtt
    11581 ttagttgtga tttcaacgtc acgtgctagc cgtttccggc gtgctaattc agctgctttg
    11641 gcattggctt tcgcagcttc cttgactgga tcagtcgtta agtcgtgatg gatcgagtac
    11701 agtaagacga gcgcgacaat cgttaatggg aagccagaca tcgcacagat ggactgaatc
    11761 gattcaaagc caccgaccgt gacaagcccc aatgagaaga ctaggaagat aacgacccag
    11821 ctcatccgat tgaaacgact tggttgttcc cccgcggcca actttttact agtaaatgac
    11881 gaggtaatga aggcaaatga agataccgtc gttgctaaga aaataaagca agataggcag
    11941 tacaaagcca gcataatcat cttcaatggt aaggtcgaca atactgctgc aatcacagcg
    12001 gcttgtcctt gcgtatttaa gatatgaact aagttaacga tgcccatccg ttgcaagtat
    12061 aaggcataac cacccaagat ggcgtagaaa ctgacacaac ctaatgagcc ccatagcaac
    12121 ataccaccga gtacctgacg aatcgtccgg ccccgagaaa tccgggcaat gaataagccc
    12181 atgactggca taaaggataa ccaccagccc cagtagaaga tcgtctgccg ttgcatggcc
    12241 gttgcgtgac catttggtgc agtattcgtg ctcaacgtaa taaacttatt gacaaacaag
    12301 ccaatactat tagtttccga gtttaaaata tacaaagttg ggccaacaat taaaacaacg
    12361 attaggaagc caatcgctaa ccaaacatgg gcagcactta gccgaccgat tcccttcttc
    12421 aagccattaa aaacagccat ggcgaaaatt acgaataata aggcaaataa ccctaacttt
    12481 aaagtcatcg tatcggcaat cccggtaacg gcactcaaaa cttttgaaat gacggggatt
    12541 tccatcccga ctgaagtacc aacaccaccc ataatcccaa taataacgag aaaatcaatc
    12601 gtgttccggg caatttgctt acccttacca ggaccttgta gtactgaaat tgcggcactg
    12661 agccgctgaa ccttgatgtg tttaacatac attgcatagg caattgcaat cgtggctggc
    12721 gcaaacatca tccacgccat tggtccccaa ttaaattgtc ccagcatgtg cgcataatta
    12781 tatgcagaag ttgaaaacgg cttgacgccg aatgaagggc tttggaggta ccgtaacggg
    12841 tcaaccatgc tcaacattaa aatgctggca tcgatcccgg tcgcgtaaac catactgccc
    12901 cagtgatacg ttgaaaattc tggtttgtca tcaggatcac caagtttggt tttccctaac
    12961 ttactaaacc ctaagtaaat gaaaaagata aaagtgatca catataccga catataaagc
    13021 cagctcatgt tatttgtgag ccagttcaag atgccactta aactcgtctc cagcgaatgg
    13081 ccccccatta ataaaacaac ggaagccgcc gcaaagagcc caattgttgg taaatagacc
    13141 caccaatcaa tattcttact ttttaaaata ataaacctgc tactgagcat atactctcta
    13201 tatttagatc aaattcgtgg ttcttcctac cagcaatggt agtccccacg cgtaaatttc
    13261 cgactagcaa tcggtacacc cctccgagtt aatcctcgga gcactcagca ccctgactgt
    13321 atcaggtttg accggcattg tcatccgcat tctgtttgtg ctaactcaaa atcagtagca
    13381 gaatttcctt ctttccgttg gttgaatccg gacaacgcca tactgacaaa tgatttttaa
    13441 ttgcttaatc gacgttggtg ttcatcttgt ttagctagtg tttctattac catcgtgcct
    13501 ttagcacacg accgtcgtca caccacgtaa cgattaatgg ttacactgct cttgctaata
    13561 gataaccccc ttgaatcacc agataagccc accgcacaac tgttagatta attgcttggt
    13621 gcaccaaaaa agcgcttagt accgggtaac aagttaccac ctgcacagcg cacgttggct
    13681 tatacaaatg ctgatttcag tattttctga tatctgatgt tcgtttataa gtatactagt
    13741 attaaatcag aagtaaaatc aaccattttg agccgtcgag gcctaacccg tcaaggatta
    13801 gacgagtttt acacccatat tttttctgaa actttttaaa agttttcgta ataattagtt
    13861 tttagtttag aatcattctt atctgtttca attaaaccga tttcatgtta ttcttgtaac
    13921 aagtaaaaaa acgttatcat ctaaaaggag gggaactgca tgcggcacta ctataaatta
    13981 attttaacgg tcagcgtcgg tatcattgcg gttattttac agtttggttt gcactaccaa
    14041 ttggcagcac aaatcatcat tacattaatg gggtcactta tggccttatc aatgttagtt
    14101 gagatgatca aaaccttacg ttcaggtaag tacggggttg atttattagc aattacggcg
    14161 attgtggcaa cactagctgt cggcgaatat tgggctagcc ttgtcgttct aattatgctc
    14221 actgggggtg actcgttaga agattatgcg gccaaacgag cgaataccga attgaaagcc
    14281 ttgctcgata attcaccacg tattgcccac cgctcagtcg ccggccaatt aacagatatt
    14341 gccgttgaag atgtccaaat tggtgatcag ctagtcgtca aacctggtga gctagttcca
    14401 gtagacggtc accttattca aggaacggca ctctttgatg aatcttcatt gacgggtgaa
    14461 tctaaaccag tcgacaagca cgttggcgat gacattatgt ctggtgcggt caacggcgat
    14521 agtgccgtta caatggttgt tgataaatta gccattgata gtcaatacca acagttagtc
    14581 aaattggtta aagaatccga atcacgacca gccaaattcg tacggctggc cgatcgctat
    14641 gcagtcccat tcaccttggt agcatacgtc attgccggag tagcttgggc attcagcggt
    14701 gatccccacc gatttgcaga agtcctcgta gtggcttcac cttgcccgct gattctcgcc
    14761 gcacccgttg cactcgtctc agggatgagc cgaactagtc ggaacggaat cgtggtcaag
    14821 actggggaca tgttggagaa gttatctacg gctaagtccg ccgcgtttga taagacgggg
    14881 accattacca gtggtcaatt aacagtcaac caaattgttc ctcagcctgg ttttactgcc
    14941 gaacaaatct tgcacctcgc agcgagcgct gaacaaaact caagtcatat cctggcccgc
    15001 tcactcgtca agtatgcgag tgccactagc ctcagcccgg caacacaatt agcagaagta
    15061 acgggtaatg gggtcacggc aacgattgag cagcaacagg tcaaagtggg caaacttaaa
    15121 ttcgtcgcac cgactacaac cgccaagcca cttgctacta ctgctatcta cgtcggcatc
    15181 gatgaccagt acgcgggtta catcacgttt atcgacaatg tccgccccga agcagccgcc
    15241 acgcttcaag cactccacgc tgagggcgtt caaaacgtca tgatgcttac tggtgaccaa
    15301 caggcaattg ctgatcatat tgccgccgat gtcggtatcg ataccgttgc tgccgacctc
    15361 ctacccgcag ataagattgc ccacttaaag gctgtaccag cggccgaacg ccccgttatc
    15421 atggttggtg atggtgttaa tgacgcgcct tccttggctg ttgctgacgt cggcattgcc
    15481 atgggcgccc atggctcaac tgctgctagt gaatcggccg acgtcgtcat cttaaaagac
    15541 gatctcagtc gcgtggtcac ggcggtgcgc attgctaaag ataccatgca agtggctaaa
    15601 caagccgttt ggat
//
