LOCUS       c00018_gnlPro..        13862 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDKMOJKM_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:30:41
            Original ID  :: gnl|Prokka|HDKMOJKM_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 90414
            Orig. end    :: 104276
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13862
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[100414:103440]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13026
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13862
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13862
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             734..2434
                     /locus_tag="ctg18_65"
                     /transl_table=11
                     /translation="MKKVLLILACGIATQLSYAQATPKWADKAKKAVFSIVTYDKDNKI
                     KNTGNGFYINENGTALSDYTLFEGAERAVIINADSKELPVLRILGANSMYDIVKFNTEA
                     DKKTIALKSASQPASVGETVYLLPYSTQKAATCQTGTVTKVDTIGDKAYYYTLAMTTNE
                     KTVSCPIMNANGEVLGLIQKNASDEAKESYAIGATYGTSLSITALSLNDMSLNKIGIKK
                     GLPETEDQALVYLFMASSQQNQNEYITTLNDFLEQYPNSADGYIRRATTYMGFSDDEHN
                     ALADADLKKALEVTTNKSETQYNIAKLIYSYIISLGDKKPYGDWSYDKALSIIHDAMQA
                     DNQPIYTQLEGDILFAMKKYPEAYAAYEKVNQSSIASAATFYSAAKTKQLIEGTDMNEV
                     IALMDSAVARFTKPYTSEAAPYFYERAEIKAQTGKYREAVIDYDTFYDAIGGRVTAAFY
                     LQREQAEIQCKMYQQAINDINKAVEMTPEDVAMWVEKGSVHLRVGQHNEAIEALEKAIS
                     LDPKAAAAYRMLGYCQIQLKKNKEACANFAKAKELGDEVVDGLIQKYCK"
     CDS             complement(2573..3877)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_66"
                     /sec_met_domain="ATP_bind_3 (E-value: 1.5e-51, bitscore:
                     167.0, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFHWNIQKYIEEKQLFTLHDKVLVALSGGADSVALLRVLLVLGYH
                     CEAAHCNFHLRGEESDRDERFVNELCKGLGVALHVTHFDTVTYASRHHVSIEMAAREMR
                     YDWFEQLRKERGGAVIAVAHHRDDSVETFLLNLIRGAGINGLKGISPHNGCIVRPLLEV
                     SRQDILDYLRCLRQGYVTDSTNLQDEYMRNKIRLNILPMLRELNPSVSESIAETSRRLT
                     DVSLIYNKEIEAGKERVMEKSGHILISRLMEESAPAALLFEILHPLGFNSVQAGDVFRS
                     LSAQSGKRFVSAGWEVLRDRTELIIRRRKLADEEVEENVPPFRLAMETQEIMPDFVIPK
                     NKDTACLDADKVVLPLTVRKWRQGDKFVPFGMKGKKKISDYLTDRKFSLFQKENQYVVC
                     SAGQIVWLVGERSDDRFRVTEDTKRVLIIQQLWDK"
     CDS             3998..6466
                     /locus_tag="ctg18_67"
                     /transl_table=11
                     /translation="MRLSELRTGEKGVIVKVLGHGGFRKRIVEMGFIKGKTVEVILNAP
                     LKDPIKYRLLGYEISLRRQEADMIEVVSEQEARTMQNPYHGSITEDVPVPESELVALAK
                     GKRRTINVALVGNPNCGKTSLFNIASGAHEHVGNYSGVTVDAKEGFFDFQGYHFRIVDL
                     PGTYSLSAYTPEELYVRKHIIEETPDVIINVVDSSNLERNFYLTTQLIDMNVRMVIALN
                     MYDELEASGNKLDYTQLSQLIGVPMVPTVCRRGEGVDKLFHVIIGIYEGGDFLSQKGEI
                     RSEILEDLRDWHKTYVPDHEFGSHKEEEDARPRGYMRHIHINHGPELERSIEEVKKAIS
                     QNEDIRHKYSTRFLSIKLLENDREIENFISTLPNGKEIIAIRNKETLRIRKVMNEDSEQ
                     AITDAKYGFITGALKETFTDNHLEKEQTTRVIDSIVTHRIWGYPIFFLFLYIMFEGTFV
                     LGDYPMQGIEWLVDQLGNLIRNNMAEGPLKDLLIDGIIGGVGGVIVFLPNILILYFFIS
                     ILEDSGYMARAAFIMDKIMHRMGLHGKSFIPLIMGFGCNVPAIMATRTIEDRKSRLITM
                     LVNPLMSCSARLPIYLVMIGAFFPNCASFMLLCIYTAGILLAVIMARIFSKFLVKGEDS
                     PFVMELPPYRMPTSKSIMRHTWEKGAQYLKKMGGIIMIASIIIWFLGYYPRHDTHESVA
                     EQQENSYIGQIGKAIEPVIKPLGFDWKLGIGLISGVGAKELVVSTLGVLYTNEGDVENV
                     NLSDRIPITPLVALAYMLFVLIYFPCIATFAAIKQESGSWKWAIFAAGYTTGLAWLVAF
                     TVFQIGSIII"
     CDS             complement(7031..7711)
                     /locus_tag="ctg18_68"
                     /transl_table=11
                     /translation="MKEYRLRVKEKIMKADLATIRREYTKGGLKRSDLPDNPLVLFTKW
                     LQEAIDAEVNEPTAMLVGTVSPEGKPAIRTVLLKDLHDGKFIFYTNYGSRKGKHLAHNP
                     SISISFVWHELERQIHIEGIAAKVSPQESDEYFRKRPYKSRIGARISPQSEPIESRIQL
                     IRDFVKETTRWIGKEIDRPEYWGGFAVMPVRVEFWQGRVNRLHDRFLYMLQSDGVWKIE
                     RLAP"
     CDS             8137..9231
                     /locus_tag="ctg18_69"
                     /transl_table=11
                     /translation="MKILLIGEYSNIHWTLAKALRNMGHRVDVLSHSNLWLNNSDYLYP
                     NRSSIRWGVLKNTFNLLKTLPQLRGYDVVQLVNPYFLELKPELLQYVFQYLKKNNKKIF
                     LGGFEYDFYWIYMCLNKNALRYNDFYANGTFRDTIDNKMAIINWMHGFRGKLNRIIANN
                     CNGIITSLYESYLAYQPYFSGKTKYIPFPIESLPHPQIPFKKIEKVKFYISLKHHREEW
                     KGKDELYSALYKLYYRHPSACEIKQTVFTPYDECEHFMDGCDVMLDQLYSYSPGLNALY
                     AMSKGIVVVGGAEEEHYNLLGEDRLRPIINVRPEGNDIYNKLESLLANTNKISQLSADS
                     IEYIKKHHCPIKVAKECLDFWEKN"
     CDS             9204..9395
                     /locus_tag="ctg18_70"
                     /transl_table=11
                     /translation="MFGFLGEKLIPPINTSLSAPYYFHQKIYLKKRAKGLHISIYPLIF
                     APRLRDNASDKKEVWVSG"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_71"
                     /sec_met_domain="Gly_radical (E-value: 4.9e-47, bitscore:
                     151.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEMNKVFKDGLWSKEINVSDFVHTNITPYEGDASFLAGPTERTKK
                     VWNECLKALEEERANNGVRSLDNVTVSTITSHKAGYIDRENELIVGLQTDELLRRAIKP
                     YGGIKVVEKACHENGVEVDEKVKDIFTHYRKTHNDGVFDAYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLHNITSPMTDARIRLREEVAEQIKALKEIK
                     ILGEYYGLDLGRPATNAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYIQYDLDH
                     GKIDESFAQELVDQFIIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKEFCAQVSIDTSSIQYENDTLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKDIPVLTGDLL
                     NFEEVWSNYKKVLMQIARVYNDAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYGKVRAKRNDIGLTEGFDIENAYPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKHPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDAQDGISNTFSIVPKSLGVDQETRIENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFIKLSREHQLEVISRSFHERM"
     CDS             12298..13026
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 77.8;
                     E-value: 3.2e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_72"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-27, bitscore:
                     89.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIDTKGE
                     STETTIDEIVRMAVSQKAFFGKKGGVTFSGGEPTLQAKALIPLFQRLKEQSIHICIDTN
                     GSIWNEEVKELLQWTDLVLLDIKEFNNVRHRQLTERSNEQTIRTAGWLEKNGKPFWLRY
                     VLVPGYSSFEEDIRALGEHFKNYQMIQRVEILPYHTLGVHKYEAMGKEYKLNGIKENTL
                     KQLETAKTLFGEYFNTVYLN"
     CDS             13128..13775
                     /locus_tag="ctg18_73"
                     /transl_table=11
                     /translation="MKRLLLLCLTYIMCVGNHQMAAQDSSESPGIFNSLAVGVSASTTG
                     IGIDIASPIGSYLAVRAGVSFMPNFTYSTDVDVDIEGSYEGNIPTSIDVEGGMGRTAGE
                     ILLNVYPFKSSSFFVCGGAYFGGGKLIKIKGHSDELAELIKEGQEVGIEIGNYRIPVDQ
                     NGNISGGLKVSSFRPYLGLGFGRAIPKKRIGFMFEMGVQFHNTPKVYTNKGA"
ORIGIN
        1 gataaagtat tggtgaagaa agatatacag agcgaactgt ccaaagaact gtttgcctgt
       61 ttgaaaaata ccctcatccc tgttcagcgt gtacccgtgg agcgtattaa ccgtatcacc
      121 cggaaaaacc atcagggagt tgtagcattc atctcctctg tcacctacca gaaaacagaa
      181 aatctggtac ctttcttgtt tgaagaagga aaaacaccct tattcgtcat gctggatgga
      241 attaccgatg tacgtaactt cggagccatt gcccgtacct gcgaatgtgc cggtgcagat
      301 gccattatta ttccctcgaa aaacagtgtc agtgtcaatg ctgacgcaat gaaaacatcc
      361 gcaggagctc tgcacactct tcccgtatgt cgcgaacaaa gtttgactaa taccatcaag
      421 tatctgaaag actgcggatt caagattgta gcagctacgg aaaaagggga ttatgattac
      481 accaaagcaa actataaaga ccctgtatgt atcattatgg gagccgagga cacaggtgtt
      541 ccctacgagc acctttctct gtgcgatgaa tggatcaaaa taccgttaat gggtaaaata
      601 gaatcactga acgtatcggt tgccgcaggt attctgattt atgaagctgt aaaacaacgc
      661 ggcttcacag aagacaagac ggcatccgct ttataaaata ccgtatcatc gttaacaaac
      721 aattaactat atcatgaaga aagtactttt gatattggca tgcggcatag ctacccagct
      781 aagctatgca caagcaaccc caaagtgggc cgacaaagct aaaaaagccg ttttttccat
      841 cgttacatac gataaagata acaaaatcaa gaatacagga aatggattct atatcaatga
      901 aaatggaacg gcattatctg attacaccct gtttgaagga gccgaacgcg cagtaatcat
      961 taacgcggac agtaaagaat tacctgtatt gcgtatcttg ggagccaact ccatgtatga
     1021 catcgtaaaa tttaatactg aagccgataa aaagaccata gcattaaaat cggcatcaca
     1081 gccggcatca gtaggtgaaa cagtctatct gctaccctac tcgactcaaa aagcggcaac
     1141 ctgccagaca gggaccgtca ccaaagtaga caccattggc gacaaggcat attattatac
     1201 actggcaatg acaaccaacg aaaaaaccgt aagttgccct attatgaatg ccaatggaga
     1261 agtattaggt ttaatccaaa aaaacgcatc ggatgaggcc aaggaaagtt atgccatcgg
     1321 agctacatac ggtacctcac tgagcatcac cgccctttct ttgaacgaca tgtcactgaa
     1381 taaaatcggc atcaaaaaag gactgcccga aacagaagac caagcattgg tgtacctgtt
     1441 catggcatct tcacaacaaa atcagaacga atatatcacc acattaaacg attttctgga
     1501 acaatatccc aacagcgcag acggatatat acgccgtgcc actacttata tgggatttag
     1561 tgatgatgaa cacaacgctt tggcagatgc tgacctgaag aaagcactgg aagtgactac
     1621 caacaagagt gagacgcaat ataatatcgc taaattaatt tattcgtaca tcatctcttt
     1681 aggtgacaag aaaccatacg gtgactggag ttacgacaaa gctctctcca tcattcatga
     1741 tgccatgcaa gccgacaacc aacccattta cacacaattg gagggagata ttctgtttgc
     1801 tatgaagaaa tatcctgagg catacgccgc ttatgagaaa gtgaaccagt cttccatagc
     1861 ctctgctgct acattttact cggcagccaa aaccaaacaa ctgattgaag gaacagatat
     1921 gaacgaggtt attgccttga tggatagtgc tgtggcacgt ttcaccaagc cttatacatc
     1981 ggaagctgct ccttatttct atgaacgggc agaaataaaa gcccagacag gtaaataccg
     2041 tgaagcggta atagattatg atacttttta tgatgctatc ggtggacggg ttacagccgc
     2101 cttttatctg caacgcgaac aggcggaaat acaatgtaag atgtatcagc aagctatcaa
     2161 tgacattaat aaagcagtag aaatgactcc tgaggatgta gccatgtggg tggaaaaagg
     2221 ttcggtgcat ctacgtgtag ggcaacataa cgaagcaata gaagcattgg aaaaggctat
     2281 ctctttagac ccgaaagccg cagccgcata ccgcatgctg ggatactgcc agatacaatt
     2341 aaagaaaaac aaagaagcct gtgcaaactt tgccaaagca aaagaactgg gcgatgaagt
     2401 ggtagacgga ctgatacaga agtattgcaa ataataccgg aaagctccat ccaaaatccg
     2461 cgaatcttgc tacgtgattt ctgaaatctt gttgcatgat tcgcggattt ttgctacaag
     2521 atttcaggga gcattccctg ccattcatga aaaagcagga aaggaaaaaa ttctacttat
     2581 cccacaactg ctgtataatc agtacccgtt tcgtatcttc cgtcacccgg aaacggtcat
     2641 cgctacgctc tcctaccagc catacaatct ggcctgcaga gcaaaccaca tattgatttt
     2701 ctttctggaa aagagaaaac ttacgatctg tcagataatc gctgatcttc tttttccctt
     2761 tcattccgaa aggaacaaat ttatccccct gccgccattt acgcaccgtg agaggtagca
     2821 ccaccttgtc tgcatccaaa caggccgtat ccttattctt agggatgaca aagtctggca
     2881 ttatttcctg cgtttccatt gcaagccgga acgggggcac attttcctcc acttcctcat
     2941 ccgccagctt cctcctgcga ataatcaact ccgtcctgtc gcgcagtacc tcccatccgg
     3001 cagaaacaaa cctttttccc gactgggcag acaaactgcg gaatacatct cctgcctgga
     3061 cagaattgaa acctaacgga tgaagaatct caaacagcaa agccgccgga gcactctctt
     3121 ccatcaaacg agaaataaga atatgaccgg acttttccat caccctttct tttcccgcct
     3181 ctatctcctt attatatata agagaaacat cagtcagacg ccttgatgtt tcagctatac
     3241 tttcactgac agaaggattc agctcacgca acatcggaag aatattcaga cggattttat
     3301 tacgcatata ttcatcttgc aaattggtac tgtctgtaac ataaccttga cgcaaacaac
     3361 gcaaataatc caaaatatcc tgacggctca cctccaacaa aggccgtaca atgcagccgt
     3421 tatgcggact aatacctttc aagccattga ttcccgcgcc acgtatcaaa ttcaataaaa
     3481 aagtttccac actatcgtcc cggtgatggg ctacggcaat aacagccccc cccctctcct
     3541 tacgcagttg ttcgaaccaa tcatagcgca tttcgcgagc cgccatctca atagaaacat
     3601 gatgcctcga agcataagtg accgtatcaa aatgagtaac atgcaaagcc actcctaatc
     3661 ctttacacaa ctcattgaca aacctttcat ctctatcgga ttcctcacca cgaaggtgaa
     3721 aattacaatg ggcagcctca caatgatacc ctaaaacaag caagacacgc aacaaagcta
     3781 ccgaatctgc cccgccactc aatgccacta acaccttatc atgcaaggtg aaaagttgtt
     3841 tctcctctat atacttctga atattccaat gaaacatggc acaaagataa gagttctgca
     3901 agacaaaaac aaagtgcccg ttctttattt aaaaacaatc taaataattt gcatacttct
     3961 aagtaataac ttatctttgc aaaaaattta aaacaaaatg cgtttatccg aattaagaac
     4021 aggagaaaaa ggcgtaatag tcaaggtttt aggccacggt ggtttccgca agcgaatcgt
     4081 tgaaatgggt tttattaaag gaaaaaccgt agaggtaatc ttgaacgccc ctttgaaaga
     4141 ccctataaaa tacagactac taggttacga gatctccctc cgaagacaag aggcagatat
     4201 gattgaggtg gtaagcgagc aggaagcacg cacgatgcaa aacccttacc atggttccat
     4261 aacagaagat gtacccgtgc ccgaatcaga actggtggca ctggcaaaag gcaaacgccg
     4321 tacaatcaat gtagccttag taggtaatcc caattgtgga aagacttcgc tattcaatat
     4381 tgcatctggc gcccacgaac atgtaggaaa ctacagtggt gtgacagtag atgccaagga
     4441 aggttttttc gacttccaag gttatcattt ccgtattgta gatttacccg gaacctattc
     4501 tctttcagcc tatactccgg aagaacttta tgtacgcaaa catatcattg aagaaactcc
     4561 ggatgtaatt atcaatgtgg tagactcttc taacttggaa cgtaatttct atcttaccac
     4621 ccaattgatt gatatgaatg tgcgtatggt tatcgccttg aatatgtacg atgagctgga
     4681 agccagcgga aataaattgg attataccca attaagccag ctgatcgggg tgcctatggt
     4741 acctactgtc tgccgacggg gagaaggtgt agacaaactg ttccatgtta tcatcggtat
     4801 ttacgaagga ggagatttcc tgtcacaaaa gggcgaaata cgttctgaaa ttctggaaga
     4861 cctgagagac tggcacaaaa cctacgtacc cgaccacgaa ttcggaagcc acaaagaaga
     4921 ggaagatgcc cgcccacgcg gatatatgcg tcatattcat attaaccacg gtcctgaact
     4981 ggagcgcagt atcgaagaag tcaagaaagc aatcagtcaa aacgaagaca tacgccataa
     5041 atattccacc cgcttcctat ccatcaaatt actggaaaac gatagggaaa tagaaaattt
     5101 catctctaca ctgcctaatg gcaaagaaat catagcgata cgcaacaagg aaacattacg
     5161 tatccgtaaa gtgatgaacg aagacagcga gcaagctatt acggatgcta aatatggttt
     5221 tatcaccgga gctttgaaag aaacattcac cgacaatcat ttggaaaaag aacaaacgac
     5281 ccgcgtgata gacagtattg tgacacatcg catttgggga tatcctattt ttttcctgtt
     5341 tctttatatc atgtttgagg gaacctttgt tttgggtgac tatcctatgc aaggtattga
     5401 atggctagta gaccaattag gcaacctgat acgaaacaat atggctgaag gtcctttgaa
     5461 agacttactg atagatggta ttatcggtgg agtgggcggt gttatcgttt tcctgccgaa
     5521 tatcctcata ttatactttt ttatttctat attggaagat tcggggtata tggcacgcgc
     5581 cgcatttatc atggataaaa taatgcaccg gatgggactg catggcaagt cctttatccc
     5641 actgattatg ggattcggtt gtaatgtacc tgccataatg gcaacacgta ctatagaaga
     5701 tcgaaagtcc agactaatca ccatgttggt gaatccttta atgtcctgta gtgcgcgtct
     5761 tcccatatat ttagttatga taggtgcttt tttccctaac tgcgccagct ttatgttact
     5821 ttgtatctat acagcaggta ttttattagc agtaataatg gcccgtattt tcagtaaatt
     5881 tctagtgaaa ggagaagatt ctccatttgt gatggaactc cccccctatc gtatgcctac
     5941 ttctaaaagt atcatgcgtc atacatggga aaaaggagca caatatctga aaaagatggg
     6001 aggcattatc atgattgcct caattattat ttggtttcta gggtattatc cacggcatga
     6061 tactcatgaa agcgtagccg aacaacaaga aaattcatat atcggacaaa taggcaaagc
     6121 aatagagcct gttatcaaac cgctaggatt tgactggaag ttaggaatcg gacttatttc
     6181 aggtgtaggc gctaaagaat tggtagtaag tacactagga gtattataca caaatgaagg
     6241 agatgtggaa aatgtgaatc tttctgaccg tattcccatt actccactgg ttgcattagc
     6301 ttacatgttg tttgtattga tctacttccc ctgtattgcc actttcgcag caatcaagca
     6361 agaatccggc agttggaaat gggccatatt cgcagcagga tacaccactg gattggcttg
     6421 gcttgttgca tttaccgtat tccaaatagg aagtattatc atttaataaa cctaaaccta
     6481 aaattatttg tttatcaagc atggaattac aacaaattat agttattgca atcgtatgcc
     6541 tctgtacaat atggataagt atacgtatct ttcagtattt caagcgcata aagaacaata
     6601 gcaatccgtg tgaatgctgt aattctgatt gcgccatgaa gtctatgcac aacaagccaa
     6661 agtgcggttg cgaaaaaaat gcagaaaagt gagaaaaaaa tagcaaaata tttgcagatt
     6721 aaaaaaaata tcgtaccttt gcaaccgcaa tcgagaaaca aagattgata acaataaggt
     6781 tccttggatg agtggcttag tcagcggtct gcaaaaccgt gtacggcggt tcgaatccgc
     6841 caggaacctc ctcatcactt caaaaataaa tatgcaaaag ggaataatcc atagattatt
     6901 cccttttgca tataatatat aaaaagcaac gccttcaatt actcaaaagt attcctattt
     6961 acacctacat tcaaaaggtt tctcggctca gtttgaaaaa gaacctggaa ttatttctct
     7021 attccgaaga ttaaggagcg agtctttcta ttttccaaac accatcagat tgaagcatat
     7081 agagaaaacg atcatgcaaa cgatttaccc taccctgcca gaattcaaca cgaacaggca
     7141 taacagcaaa gcctccccag tattcagggc gatctatctc tttccctatc cagcgcgtgg
     7201 tttctttcac aaaatcacga ataagttgta tcctgctttc tatcggttcg ctttgaggag
     7261 aaatacgggc gccaatacga ctcttgtaag gcctttttct aaaatattca tctgattcct
     7321 gtggagatac tttagccgca ataccttcta tatgaatttg cctttccagt tcatgccata
     7381 caaacgatat agagatagat gggttatgag ccagatgttt acccttgcga cttccatagt
     7441 tagtataaaa aataaatttg ccatcatgca aatctttcaa caacacagtc cgtattgccg
     7501 gtttcccttc cggagaaaca gtacctacca acatagccgt aggctcattt acctccgcat
     7561 ctatcgcttc ttgcagccac tttgtaaaaa ggacaagtgg attatcagga agatcactcc
     7621 ttttgagacc accctttgta tattccctcc tgattgtcgc caaatcagcc ttcattattt
     7681 tttctttaac tcttaaccta tattctttca ttaacactta aatattcttt actcaataaa
     7741 ttccccaaaa gaccatatca aaatggacac catacctcac ataagtatga aaacaatctt
     7801 ctaaaagaaa aggtttagca atttctcacc gctatgcata attgaagaag gacttatttt
     7861 catttttttg aaatacaaaa tctttttgca aaccatacat tttcaatcat tccactacac
     7921 acatttttct gtaatacaag aagatatatt tttgatagat ttaattttca tagacaatac
     7981 tagctacaac agaagacaaa ttatcctttt ttattgcaaa atcaccctac aataagaact
     8041 aaagcctaca cttgtttgtt aaatagaaaa ataagaatag caaaacgact tgctaccaat
     8101 gcacaaacta tttaattaaa taatgattga ctgtttatga aaatcttatt aataggagag
     8161 tatagcaata tacattggac tttagcaaaa gccttaagaa atatgggaca tagagtcgat
     8221 gtattatccc acagcaattt atggctaaac aactctgact atctctatcc caaccggtca
     8281 tcaatccgtt ggggagttct taaaaacacg ttcaatttac tgaaaaccct tccccaactc
     8341 agaggatatg atgtggtaca acttgtcaac ccttactttt tagaattaaa acccgaactg
     8401 cttcagtacg tattccaata tcttaaaaag aacaacaaga agatattttt aggagggttt
     8461 gaatatgatt tttactggat ttacatgtgc ttaaataaaa acgctctccg atataatgat
     8521 ttttatgcca atggcacttt tcgtgacacc attgacaaca aaatggcaat tataaattgg
     8581 atgcatggat tcagaggaaa attaaaccgt atcatcgcga acaattgtaa tggaatcatc
     8641 accagtcttt acgaatccta tttagcctac caaccctatt tctctggaaa aaccaaatac
     8701 attcctttcc cgatagaatc attgcctcac ccacaaatcc cttttaaaaa aatagaaaaa
     8761 gtaaaattct atatcagtct aaaacatcat cgtgaagaat ggaagggaaa agacgaactt
     8821 tatagcgccc tctataaatt atattacaga catccatctg catgcgaaat caaacaaacc
     8881 gttttcactc cgtatgatga atgtgaacat tttatggacg ggtgcgatgt aatgttagat
     8941 cagctttatt cttattctcc gggattaaat gcattatacg ccatgagcaa aggaattgta
     9001 gtggtgggag gtgcagaaga ggaacattac aacttattag gcgaagacag acttcgccct
     9061 atcatcaacg tacgccccga aggaaatgac atttataaca aactagagag tttattagcc
     9121 aatacaaata aaatttctca attatccgcc gacagcattg aatatattaa aaaacaccat
     9181 tgtccaataa aggtggctaa agaatgtttg gatttttggg agaaaaatta attccaccta
     9241 ttaacacttc actatcagca ccttattatt tccatcaaaa aatatatcta aaaaaaagag
     9301 caaaaggttt gcatatttca atttatcccc ttatctttgc accgcgtttg agagataacg
     9361 cttctgataa gaaggaagtt tgggtgagtg gctgaaacca ccagtttgct aaactgacgt
     9421 acgggtaacc gtaccggggg ttcgaatccc ccagcttccg cgaataagtc gtaaattaat
     9481 tttacgactt attttttata ttcatttttc aacagtttgc tgtcaaggct ttcgggagga
     9541 agagtaaagg tgttttttag actttcaatt ttactacata aaacatatga tacttcttca
     9601 tagaaattaa attccgattt ataatagtaa tagcataaaa aaaatcattt tttattttgc
     9661 agattaaaaa caaacttcta actttgcacc gtcttagaaa aagaattaag actaactgat
     9721 ggcggtatcg tctagtggcc taggacgcag ccctctcacg gctgaaactc gggttcgatt
     9781 cccggttccg ctacttttag aagctaattg gtttattgtc accaattagc tttatttttt
     9841 atggaattgt tataaagagt ccttattgtt ttttcattta ttgaccactt tatacttaaa
     9901 aatgcacaag tattcgcatt atacctacta atagtgatgc atagctcaca aaaaaggagt
     9961 acctttgcag ccctaaatct cttaataatg gaataacagt atggaaatga acaaagtttt
    10021 taaggatgga ttgtggagta aggaaattaa tgtttcagac ttcgtacata ccaacattac
    10081 cccttatgag ggcgatgcct catttctggc aggccccaca gagcgaacta aaaaagtgtg
    10141 gaacgaatgc ctcaaggcac tagaagaaga acgtgccaat aacggagttc gttcccttga
    10201 taatgtaaca gtatctacca tcacctcaca taaagcagga tacattgacc gtgaaaacga
    10261 actgattgta ggtcttcaaa cggatgaact tctgcgccgt gccatcaaac cttatggtgg
    10321 tatcaaagtc gtagaaaaag cctgccatga aaacggtgtg gaagtagatg aaaaagtaaa
    10381 ggatatcttt actcattatc gcaaaaccca taatgatggc gtatttgatg cttacaccga
    10441 agaaatccgc tctttccgtt cactcggttt cctgaccggt ctgcccgata attatgcacg
    10501 cgggcgtatc atcggtgact accgccgttt ggcactgtat ggtatcgacc gactgattga
    10561 agcaaaacaa gaagatttgc acaatatcac cagtccgatg accgatgccc gtatccgcct
    10621 gcgcgaagaa gtagccgaac aaatcaaagc actgaaagaa ataaagatat tgggtgaata
    10681 ttacggactc gacttgggtc gtcccgctac taatgcacaa gaagctgttc agtgggttta
    10741 tatggcatat cttgctgccg tgaaagaaca agatggagca gctatgtcat tgggcaacgt
    10801 ttcttcattc ctggatatct atattcaata tgatttggat catggtaaaa ttgacgagtc
    10861 atttgcgcag gaactggtag accagttcat tatcaagttg cgtatggtcc gtcatctgcg
    10921 tatgcaatca tacaacgata tctttgcagg tgatcccacc tgggtaaccg agtctatcgg
    10981 cggacgcttc aacgacggac gtaccaaggt tacaaaaact tccttccgtt tcttgcagac
    11041 actatacaat ctgggtccgt cacccgaacc taatatgact gtactgtgga gtccggaatt
    11101 gccggaaggt ttcaaagaat tctgtgcaca agtttctatc gacacttctt ctatacaata
    11161 cgaaaacgac acgctgatgc gcgaagtgcg taactgtgat gattatggta tcgcctgctg
    11221 cgtttcttat caggctatcg gcaaacaaat ccagttcttc ggagcacgtt gcaatctggc
    11281 taaagcccta ttgctggcta tcaatggcgg acgttgtgag aatacaggaa ctgtaatggt
    11341 gaaagatatt cctgtattga caggggactt gctgaacttt gaagaagtat ggtctaatta
    11401 taagaaagta ttaatgcaaa ttgcacgtgt gtataatgat gcgatgaata tcattcacta
    11461 tatgcacgat aaatattatt atgaaaaggc tcaaatggca ttcattgata ccgatccacg
    11521 tatcaatctg gcatatggcg tagccggtct gtccattgcc attgactcat tgtctgccat
    11581 caaatacggc aaagtacgtg ccaaacgtaa tgatataggt ttgaccgaag gctttgatat
    11641 tgaaaatgca tatccttgct tcggtaatga tgatgaccgc gtagaccact taggggtaga
    11701 tttggtttat ttcttcagtg aagaattaaa gaaacatccg gtatacaaaa atgcccgccc
    11761 taccctgtca ctgctgacta tcacctccaa tgtaatgtac ggcaagaaaa caggtgccac
    11821 tcctgatggt cgtgccaaag gagtggcttt cgctccgggt gccaacccga tgcacggacg
    11881 tgacaagaac ggtgccatcg cctcattgag ttctgtagcc aaactacgct atcgtgatgc
    11941 ccaggacggc atcagtaaca cgttctctat cgtaccaaaa tcactagggg tagaccagga
    12001 aacccgtata gagaacctgg taaccatgat ggacggttat ttcaccaaag gagcacatca
    12061 tctgaatgta aatgtgctga accgtgaaat gttggaagat gcaatggaac atcctgaaaa
    12121 atacccgcaa ctaaccatcc gcgtatcagg ttatgccgta aacttcatca aattgagccg
    12181 tgaacatcag ctggaagtaa tcagccgttc tttccacgaa agaatgtaac atcacatata
    12241 cattcatcgt aggggcgggt tttaaacctg cccttaccag tttaaagaca aaccattatg
    12301 atcagagtcc attcttacga gtcaatgggg acgtttgacg gtcccggttt acgcttagtc
    12361 gtatttttac aaggatgcaa tttccgatgc ctctattgtg ccaaccccga cacaattgac
    12421 accaaaggtg aaagtacgga aacaacaata gacgaaattg tgcgtatggc cgtcagccaa
    12481 aaagcttttt tcggtaaaaa aggaggtgtg actttcagcg gcggcgagcc tacattgcaa
    12541 gcaaaagcac tgattccgtt attccagcga ttaaaagaac aaagcatcca catctgtata
    12601 gataccaacg gcagtatatg gaatgaagaa gtaaaggaac tgctacaatg gacagacctc
    12661 gtattattag acatcaagga atttaataat gtgcgccatc ggcaactgac agaacgcagc
    12721 aacgaacaaa ccatacgtac cgccggatgg cttgaaaaaa acggaaagcc tttttggttg
    12781 cgctatgtat tagttccagg ctatagttcc tttgaggaag atatacgggc attaggagag
    12841 cacttcaaga attatcaaat gattcaaaga gtagaaatac taccttatca tacattaggc
    12901 gtacacaaat atgaagccat gggaaaagaa tacaaactaa acggaataaa agaaaatact
    12961 ctaaaacaat tggaaacagc caaaacgtta tttggtgaat atttcaatac cgtatattta
    13021 aattagaaat atactgaaga caagatgttg ctataaatca atggaaatat ttcatcattt
    13081 caataaaatt atctaatttc gcatctaaaa cataaattat tataaatatg aaaagactac
    13141 tattactctg cctaacttac attatgtgtg taggcaacca tcagatggct gctcaagact
    13201 cttctgaaag tcctggtatt tttaattcat tagctgtagg cgtcagtgca agtaccacag
    13261 gtataggtat tgatatagcc agtcctatag gaagttactt ggctgtacgt gcaggagttt
    13321 cttttatgcc gaactttact tattctacag atgtggatgt agatattgaa ggttcttatg
    13381 aaggaaatat acctaccagc atagatgtag aaggaggaat gggacgtact gccggtgaaa
    13441 tattgctgaa tgtatatcct ttcaaatcat ccagtttttt tgtatgcggt ggtgcttatt
    13501 tcggaggagg aaaactcatc aagattaaag ggcacagcga tgagttggca gaactgatta
    13561 aagaaggaca agaagtaggt attgaaatcg gaaactatcg tatacctgta gatcagaacg
    13621 gaaatatatc tggtggtttg aaggtttctt catttcgtcc ttatcttgga ctaggtttcg
    13681 gaagagcgat tcctaagaaa cgaattggct tcatgttcga aatgggtgtg caattccata
    13741 acactcccaa agtatatacc aataaggggg cgtaaaataa actgtgtcat gcgctgtttt
    13801 tctttcaagc tcatcggtcg gggatcggcc agcgccaagg gggtgcacca gcactcccga
    13861 cg
//
