LOCUS       gnlProkkaLBNMMLCM_151  12547 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LBNMMLCM_151.
ACCESSION   gnlProkkaLBNMMLCM_151
VERSION     gnlProkkaLBNMMLCM_151
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 02:39:10
            Original ID  :: gnl|Prokka|LBNMMLCM_151
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12547
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12547
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2202:2547]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2203..2547
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12547
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12547
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             85..480
                     /locus_tag="ctg151_1"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             771..2159
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.3; E-value: 8.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg151_2"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             2203..2547
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg151_3"
                     /sec_met_domain="PF05402 (E-value: 5.3e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.2e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIID"
     CDS             2568..2693
                     /locus_tag="ctg151_4"
                     /transl_table=11
                     /translation="MDNEVEQLEYYPIRSLSIINFPLSIKKRLPTGGQHILSVRP"
     CDS             complement(2641..2922)
                     /locus_tag="ctg151_5"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFF"
     CDS             complement(2944..4008)
                     /locus_tag="ctg151_6"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(4082..5593)
                     /locus_tag="ctg151_7"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVEADVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             6201..6425
                     /locus_tag="ctg151_8"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             6618..8162
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg151_9"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             8204..8740
                     /locus_tag="ctg151_10"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             8774..9343
                     /locus_tag="ctg151_11"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             9356..10522
                     /locus_tag="ctg151_12"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             10546..11331
                     /locus_tag="ctg151_13"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHEANCLLIGDAYLSASSQQRQEMLHGVDALITREL
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVIA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             11371..12036
                     /locus_tag="ctg151_14"
                     /transl_table=11
                     /translation="MFEIKVSQEIKNACPVFAGAAVYAAVKNTAYCDGLWKEINTFTED
                     LTTTTQMADIKLQPVIAATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGKHLELGIGKAEEPFEGIGRGILNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDVGTTHILAIVNGYNGKEGLKEAAEMIQSLLRDYAGSDGGELIYFE"
ORIGIN
        1 tatccaaaaa aaaatgctta ctttgcagac caaatcagat ttttggagaa attgattatt
       61 aacgctaatt caaaataact aaaaatgtac ttattattca ttatcttaat ggtgattgca
      121 gccttgctga tgtgcttcat cgtgctgatt cagaattcaa aaggaggcgg acttgcttct
      181 ggtttttctt catcaaacgc tatcatgggc gtgcgcaaga ctacagattt tctggaaaaa
      241 gcaacttggg gtctggctat cttcatggtt gtgatgagcg ttgctactgc ttacgttgtt
      301 ccttcttctt ctgcagctaa agatgtattg ttggaacaag cacagaaaga acaacaaacc
      361 aatccgtata atatgcctac cggtactgct gctcctcaga cagacgctac tgctcctgca
      421 gagtctgcac cagcaacaga agctccggct actgaaactc ctgctcctgc agcagaataa
      481 ttcagtgaca ggatattcgg tttaaactta ttgagtgaac gggctttttg acccgttctc
      541 ttcattatag gcgcgaatta cgcgaattac aagagattct aatagaattg tgtaatacgt
      601 gtggttcgcg cctatcttta ttattgggtc cggtctgctc ttcttcatac aggaatatcc
      661 ggtcagatgt cctttttctt ataaaatgtt ctcctttttt agtaaaacaa atgataatta
      721 gttaactttg ttgcccgtta cgagattatt aactcctttt aaatattaca atgacagaac
      781 aattgaaaca aaagctgaat gactccgcag tgctgcgttg gagtgttcta gcattagtcg
      841 cttttaccat gttgtgcggc tacttcctca cagacgttat gtctcctctg aaacccatgc
      901 ttgaaaaaga acttctctgg gacagtttag attacggttt tttcaccagt gcttatggct
      961 ggtttaatgt attcctgctg atgctcatct ttggtggtat cattctggat aagatgggag
     1021 tacgcttcac cggaatgggt gcctgtttat tgatggtgtt tggttgtgga ttgaaatatt
     1081 atgctattac tactactttc ccggaaggtg cgatgctttt cggattcaag atgcaagtca
     1141 cattggctgc attgggctat gctattttcg gtgtaggagt cgaaattgcg ggtatcaccg
     1201 tttcgaagat tatcgtgaag tggtttaaag gcaaagagat ggctctcgct atgggactgg
     1261 aaatggcgac cgcgcgtatt ggaacaactt tggccatggt gcttaccgtt cctttggcag
     1321 acttcttcgg gtctacggat gagagcggcg tattccatac caatattccc gctccgattc
     1381 tgttctgtct cgtcatgctg tgcgtaggta ccatcgcatt cttcatctat actttctatg
     1441 ataagaaact ggatgcttca ctggatgcgg aaggactgga accggaagaa cctttccgca
     1501 tgaaagacat cgtatatatc attaccaaca aaggattctg gctgatcgca ttactgtgcg
     1561 tattgttcta ttcggctgta ttccccttca tcaagtatgc ggctgatttg atggtacaga
     1621 agtacaatgt agatccgaaa cttgcgggaa cgattcccgg attgctgccg attggcgcga
     1681 tcatcctgac accgttgttc gggtcattgt atgaccgtat cggtaaggga gccacgctga
     1741 tggtgatcgg gtcggtgatg ctgattttcg tacacactat gttcgctctt cctattctga
     1801 atatctggtg gtttgcaacg gtgatcatga ttattctggg atttgctttc tcattggttc
     1861 cttcggcaat gtggccttcg gttccgaaga ttattccgga gaaacagttg ggaacggctt
     1921 atgcgttgat cttttgggta cagaactggg gattgatggg cgtgcctttg ctgattggat
     1981 gggtgttgaa ttcttattgc aaaggtccgg ttgtagatgg tgcacagact tatgattata
     2041 ccttgccgat ggctattttt gctatgttcg gtgtacttgc cctgattgtt gccttgatgc
     2101 tgaaagcaga aaacaagaag aaaggctacg gactggaaga agcaaatatt cagaaataat
     2161 ccagtatata ttctatctga aaagatataa aagagaaaag atatggctac gaaagagaaa
     2221 ataaacctcc tggaggtgat cccttgtcgt aacgaacata ttaaagctga acaggaaggg
     2281 gagactattg tgctctcctt ccctcgtttt aaacgttcgt ggatgagtcg ttatttattg
     2341 ccgaaaggaa tgtccaaaga tattcatgtg cgtctggaag aacacggtac ggccgtatgg
     2401 aacctgatag acggccagcg gacggttcgt gagattatag aaaaactcgc agaccacttt
     2461 cagcatgaag caggctacga gtctcgtgta tctacctatc tttcccaatt acagaaagac
     2521 ggatttatta aatggataat tgattaatgg ataattgata atggaaaatg gataatgagg
     2581 ttgagcagct ggaatattat cccatacgtt cattatccat tatcaatttt ccattatcca
     2641 ttaaaaaaag attgcccaca ggaggacagc acatcctatc agtacgccca taatgatgag
     2701 cgttccccat acgaaatagc tgttatcttt ttcttttttc ttttccgaat ccttgatgat
     2761 gcgttccatc tcttccggag tcgtatccgg cagaagataa gggtcgttgt ttcttctaag
     2821 tcgccctaac ttgtcatttc tccgttcacg gcgtaagcgg gaggcttctt tgccgtcttt
     2881 cagccgacgt atcatgtcga gcatatgtcc ttcgccaccc atcgttttgt ttttttagag
     2941 gttttatttg ctttcttctc tatctacttt cagtagtcca ccggtcaccg gatcaaagta
     3001 aactttgatg gtcgagttct tgttgaataa taccggagca aggtattcta tgataccgaa
     3061 ctgagtaaca ggtatttctc cttcatacaa tttctttttg ccgtccgtca gcgtcaccat
     3121 tgcctgtccc ggtacgttat aagcaatgcc ttccatctct ttcttctttt ttccgtcctc
     3181 ttgcggaatc ttcaccgttt tcaggtcttt cagactgatg tagaatggag tgcctgccaa
     3241 atcgttgttg gcaactatac ccagcttctt tgaaaagcgg aaagctacct cattgtcgaa
     3301 ttccttatcc ggagtgaggc ggacagtaaa tgtcttttct tctttattgc ggactcccga
     3361 aaacatctcg gtcatggctt cttcctgaag attcaggttg tcgagcatga ttttgagctg
     3421 tgcgccgtcc gaaggcatat tatctgcttg tccgcgcaat aatgcgtttt tactttcgcg
     3481 gatattatag atttcctttg ctaccagttc ggccatcttg gcggttgaac ttgccatcag
     3541 aatttcttct gtgagaaagt cgcggggatt ggcttttcgt tggggagcaa cggcattgtt
     3601 tgctgcattc tttgcattgt tgctgctgta ggggacgttg attgatttga taagaccctc
     3661 ttcagtcagt tccataagag gagctacggt tttgtctttc agtttgacga aataagtagc
     3721 ttcgctgttt ggtacaccta caggtttcac tttgacactg ttcagttccc agtattcttc
     3781 gggttcggca gagacgttgg tcagtctcag gtagcggtcg gcgtatttgc tgaattcacc
     3841 cggcttatag ttgactttgt ttgcttttat ttctatttct atctgggttt tggggagggc
     3901 gtacactact ccgtagtctt ttcctcgcgt cactcctgtc agcacttcgg tctgcgcata
     3961 ggcggaagtt gccattagta gtcctgttgc tatgattaac tttttcatat tcggttcttt
     4021 ttagctgatt ttgaaaaaca aagttaatga agttattgaa taaaccgtaa gttcttaact
     4081 tttattcgct tacaagtcgc catgccgtcg gcagacaggt cacgatatca cttgcgatta
     4141 atccgatcat gccctgtttt ttctgggcga tgtctccggc caatccgtga atgtaagtac
     4201 cgatctttgc ggcgtcttcg gcgggatagc cttgcgcaag gagtgcaagg attactcctg
     4261 tcagtacatc tccgctgcct cctgttgcca taccgggatt accggtctgg ttgaagtaac
     4321 atttgccttc gggggtgata atggcggaat aagctccctt cagaatgata tgtactttgg
     4381 cagtgtgcgc cagttcgcag gctttcatca gtcgttcgta tgagtcctga catttgccga
     4441 ccaggcgttc cagctctttc gggtgagggg tgaggatgga acctttcggc agatgggtga
     4501 gcgtatgccg gtgattggcc agaatattga gtgcgtcggc atccagtacc gtcggagtct
     4561 gacaatgttc cagttgttct atcagggcgg cttccgtttc ctcgttgcga ccgagtcccg
     4621 gaccgatgcc gacagcttgg taatcgtccg tatcggtagg tacggcaaag catgtttcgc
     4681 tgacatctgc ttctaccatg gcttcggggg cggacgtttg cagaatatcg ttgttgcata
     4741 acggcgcgtg tacggtcagc agacctactc ccgagcgcag acaggcacgc gcggccagta
     4801 ccgatgcacc tgccattcct tttgagccgg ctatcagcag ggcatgtccg aagtttcctt
     4861 tatgggcgaa ttgttggcgt ggtttgatca gtgaacggat ttcttcgatt tccagcattt
     4921 cgtagtttgt ttcagtctct tcgattcctt cttcgctcag ctggatgtcc aataactccc
     4981 attcgccaac aaattctgta ttttcggcaa agaggaaggc cagtttagga agttgcaggc
     5041 tgaaagtgac gtccgcacgg ataatattgc tttttacatt gaatgtattt tcttctccca
     5101 tcagtccgga agggatgtcg atggagacta ccatggcggg agaggcattg atatatttca
     5161 caacggcagc gaatcctccg ctcaatggtt tgttgagtcc ggaaccgaat aatccgtcga
     5221 tcacgagatg ttccggtgtc agtgtgggag gtacgaactg ggtgctgatt tcatggaaag
     5281 ttacttcttc catcatctct accagttctt tgttggtctg gcagtcgggc gaaagttcgc
     5341 ctttcgtgtt gaagagatat acttcgatct tgtatccttt ttccgccatc atgcgggcga
     5401 tggcgagggc gtctccgcca ttattgcccg gtccggcaaa gatggtgaca ggtgtttccg
     5461 gattccatct gttggtgatg gctttagtca gcgcctgtgc ggcacgctcc attaaatcta
     5521 tggatgcaat cggttcatgt tcaatggtat aggcatctaa cttcttaatg ctgctgcttg
     5581 gaaatatttt cattgcgata ttcttttagt tttcgacgca caaacttaca caaaaactct
     5641 gaattaatcc tttattccgg ttggttttcg gctttagata aagtggcaaa ttgaaaaatg
     5701 caggggaaat cagaagttat cttggggtgg aggtacgggc attcttcaga taagatgcgg
     5761 agacttttcg gctaagatgc aggcattctt ctcttaaagt gcctttttct ttagttgctc
     5821 acggccgtga caagacttcg ccacgaccgt gagcaatgct aatcacggtc gtgaacaatg
     5881 cttgtcacga ccgtggtcag ttaatgatat cggtgctttg atgtaactat tctactgctt
     5941 tctccttaat cttccgatac tttgagagat agttacgcct tctccggcct gctatagaac
     6001 tgcttccttt atgagtgtct tcggcgtttg gaataaagct gtcagtagat atggtacaat
     6061 ataaacagct aatgccttga ttatttgctt ttttcgaaaa aaatgatatc tttgtagtgc
     6121 agtaatgtgc tttacgttat tctcctgtgc tcacaatgtt tagattataa atataaattg
     6181 tttaatcttc taaagtttgc atgatggaaa agaaaagaat tggctcaaat gccgggaaag
     6241 tatggcgcat cttaaatgaa aagggcgaac agtctatgtt caccttgtgc catgagttag
     6301 gtttgacgtt cgaggatgta gcgattgcta tcggctggtt ggcaagggaa aataaaatcc
     6361 tgcttagaaa aaaagaagga atgctctatg ccagtattga gaatgttgaa tttacttttg
     6421 gataaatggc gactgaccca catttaaggg gaatatccac ttgattattt acactgttga
     6481 aaacataata aggtgggtaa ctgagacttc ttgcacgcca tcctgtattt ttctattcca
     6541 taagaatctt cttttttgag gcatttaatc tactttttag tacctttgca ccccataaac
     6601 tactaaacac ataattcatg agttcattga aagggcaccc gaaaggcctt tacctaattt
     6661 tcgcaacgag cacggcagaa cgtttcagtt actacggtat gcgtgccatc tttatcctct
     6721 ttctgacgca ggcattgctt tttgataaag aagcggcagc ctctatctac ggtagctaca
     6781 ccggactggt ctatctgact ccgttgatcg gcggatacat tgccgataaa tattggggca
     6841 tccgtcgttc ggtattttgg ggagcggtga tgatggcagt cggtcagttc ctgatgttta
     6901 tgagtgcctc ttcactgaac aatacagacc ttgcccactg gctgatgtat ggcggactcg
     6961 gattcatgat tttaggtaac ggttgcttta agcctaccgt ttcttcgctc gtcgggcaat
     7021 tatatgaacc cggggacaaa cggttggatg ctgcatacac cattttctat atgggtgtta
     7081 atgtaggttc tttcgctgct cctttgattt gcggtttctt gggagacaca gggaatccgc
     7141 aggactttaa atggggattc ctcgcatccg gaatcatgac gctgttcact gttgtcctct
     7201 ttgaaactca gaagaataaa taccttttct ctccttccgg tgaaccaatt ggtatcgtcc
     7261 ccgacgccag acgtgaaaaa aaggaggata aagccgaaca tatttcacat ccgaagatgg
     7321 acaaacgtac caaagtacgt aatatcatca tcattactgc ccttacagtt gccttaatag
     7381 ctttttttag ctatgccttt agcgatgact ggattagtgt gggtatcttt acggcttgta
     7441 ttgtctttcc agtactcatt ctgctggatg gttcattgac caaagtagaa cgtagccgta
     7501 ttttcgtaat ctatatcgta gctttcttcg tcattttctt ctgggcagct tacgagcagg
     7561 caggagcttc tctgacatta ttcgcttccg aacagactga ccgcagcatt ttcggctggg
     7621 agatgccggc ttcgtggttc cagtcattca atccgctttt tgtagtgatc cttgcctata
     7681 ttatgcccgg tatatggggc tttctgaata agcgaaacat ggaaccggct tcccctacca
     7741 aacaggcaat cggtctgttg ctgctttctc ttggttatct cttcatctgt tttggagtga
     7801 aagatgctat tccaggagta aaggtgagca tgatctggct gacaggactt tattttattc
     7861 atacaatggg agaaatcgct ctgtcaccta tcgggctttc tatggttaat aagttgagtc
     7921 cgttacgttt cgcctccttg atgatgggga tctggtatct ttctaccgcc accgcaaata
     7981 aatttgcagg tatgctgagt ggcctctatc ccgaagacgg aaaagtgaaa tcaatccttg
     8041 gttatcagat cgctaccatg tatgacttct tcatgctgtt cgtcattatg tccggtgttg
     8101 cctcactgat tctgttcctt ctctcgaaga aattacagaa gatgatgcac ggggtagaat
     8161 aaaaaattgt atttttgcga caactttttt aaaatgaccg gttatggata ccatacagat
     8221 aaaagacaag caatttactg tttccattaa ggaacaggat attcaaaaag aagtgattcg
     8281 cgtagcgaac gaaatcaatc gtgatttggc aggtaagaat ccgctcttcc tcagtgtgtt
     8341 gaacggctcg ttcatgttta ccgccgactt gctgaagcat attacgattc cgtgcgaaat
     8401 ttcattcgtg aagttggcat cttatcaggg ggtgacttcc accggagtaa ttaaagaagt
     8461 gatcgggctg aatgaagaca ttgccggacg tacggtagtg atcgtagaag atattgtaga
     8521 taccggactg acgatgcagc gtctgctgga tacactgggc acacgcaacc ccgaagcgat
     8581 tcatatcgcc tctttgctgg tgaaaccgga aaagctgaag gtcaatctga acatagaata
     8641 cgtagcgatg gaaataccga atgattttat cgttggctac ggattggatt atgatggttt
     8701 cggacgcaat tatcccgata tttatactgt agtagattaa attcaaatac aaattaattt
     8761 ttaggttaaa aagatgttga acattgtaat tttcggtgct ccgggttcag gaaaaggaac
     8821 gcagagcgaa cgtattgtag aaaagtatgg aatcaaccac atctcgacag gagatgtatt
     8881 gcgtgcagaa atcaagaacg gcacggaact gggcaaaact gctaaaggtt acatcgacca
     8941 gggacagttg attccggatg aattgatgat tgatattctg gcaagcgtat tcgatagctt
     9001 caaagacagc aaaggtgtaa ttttcgacgg tttcccaaga acaattgcac aggcggaagc
     9061 attaaagaag atgttggcgg aaagaggaca ggatgtttct gtaatgttgg atctcgaagt
     9121 tccggaagat gaactgatgg tacgtctgat caaacgtggc aaagactccg gtcgtgccga
     9181 cgacaacgaa gaaacaatca aaaaacgtct gcatgtatat cattcacaga catctccgct
     9241 gatcgactgg tacaagaacg aaaagaaata ccagcatatc aacggtctgg gtactatgga
     9301 tggtatcttc gctgatatct gcgaagcagt agacaaattg taataaataa aaaatatggc
     9361 tgaatcgaat tttgttgatt acgtaaagat atactgtcgc tcaggtaagg gcggaagagg
     9421 ctctacgcac atgaggcgcg agaaatattg tcctaacgga ggtcccgatg ggggcgatgg
     9481 tggaagagga ggccatatta tcttgcgcgg taaccgtaat tactggacat tgcttcactt
     9541 gaagtatgac cgtcatgcga tggcaggtca tggcgaatcg ggcagcaaga accgtagttt
     9601 cggaaaagac ggtgcggata aagtgatcga agtaccctgc ggaacggtag tgtataacgc
     9661 cgaaaccgga gaataccttt gcgatgtgac ggacgacgga caggaagtga tcttgctgaa
     9721 aggcggtcgt ggcggtcagg gcaacagtca tttcaagacg gctacccgtc aggctccgcg
     9781 ctttgcgcag ccgggcgaac cgatgcagga aatgacggtg atcatggagc tgaaactgtt
     9841 ggcagatgta ggactggtag gtttcccgaa tgcgggaaag tctacgttgc tttctgccat
     9901 ttcggctgcg aaaccgaaga ttgccgatta cccgtttacg acactcgaac cgaatctggg
     9961 aattgtttcc tatcgcgatg gaaagtcatt cgtgatggcg gacataccgg gcatcatcga
    10021 gggagccagt cagggaaaag gattgggact gcggtttctg cgtcatatcg agcgtaactc
    10081 gttgctgttg ttcatggttc cggcagatag cgatgatatc cgcaaggagt atgaagtatt
    10141 gctgaatgag ctgcgtacgt tcaatcccga aatgctggac aaacaacgtg tgctggctat
    10201 cacgaagagc gatatgctcg atcaggagct gatggacgag attgaaccga cattgcccga
    10261 gggtgttccg catatattca tttcttctgt ttccggtttg ggaatctcag tgttgaaaga
    10321 cattctgtgg gaggaactga acaaggaaag taataagata gaagacattg ttcaccgtcc
    10381 gaaagacgtg acccgtctgc aacaggaact caaggacatg ggcgaggatg aagaactcga
    10441 ctatgaatat gaggaagacg ctgacgacga cgatgatgat ctcgactacg aatacgaaga
    10501 agaggattgg gaagaaaaat gatttcaatc acaagagata aaagaatgtt ggggtatgag
    10561 tcgttaagct catactccaa catttctcat tttgtaacta cccggcaggg agggtgcagc
    10621 gaaggaaatt atgcgtcatt caactgtacg ccctacagtg gagacgaggc ggaaaaggtc
    10681 cggcggaatc aaacgcttct gatggaagga atgtcgcaga cacccgaaga actggtgatt
    10741 cctgtgcaga ctcatgaggc gaattgcctg ctgatcgggg atgcttattt atcggcttcg
    10801 tctcaacaac gacaggagat gctgcacgga gtggatgctt tgattacccg cgagttggga
    10861 tattgccttt gcatttctac tgcagattgt gttcctgtgt tgatatatga taagaaacat
    10921 agtgccatag ctgccattca tgccggatgg agagggacgg tagcatacat cgtgcgtgat
    10981 actttgttgc ggatggagaa ggagtttggc acaagtggag aagatgtgat agcctgtatc
    11041 ggtccgagta tctcattggc ttcttttgaa gtgggtgagg aagtgtacga agcatttcag
    11101 aagaatggtt ttgatatgcc tcgtatttct atcaggaaag aggaaaccgg aaaacatcat
    11161 atcgacttgt gggaagcgaa ccggatgcaa atccttgctt tcggtgtgcc gtccggccaa
    11221 gtggagcttg cccggatatg tacgtatatt catcacgacg agtttttctc ggcaaggcgt
    11281 ttgggcatta agtccggacg gattctgtcg gggatcatga ttcataaata atagacttga
    11341 acgtaagttg atataaactt gaatagaagt atgtttgaaa taaaagtatc tcaggaaata
    11401 aagaacgcct gccctgtttt tgccggagca gccgtatatg cagcagtgaa gaatactgct
    11461 tactgcgatg gactttggaa agaaataaat actttcacag aagacttgac taccaccacc
    11521 caaatggcag acattaagtt gcaacctgtg attgctgcta cccgtgaggc ttataagcgt
    11581 tgcggaaaag atccggggcg ttatcgtccg tcggcagaag cgctgcgccg tcgcctgatg
    11641 cgtggcatcc ctttgtatca gattgatact ttggttgacc ttatcaatct ggtttctctc
    11701 cgtaccggac attctatcgg tggcttcgat gcggataaga tacagggtaa acatcttgaa
    11761 cttggcattg gcaaagcgga agaacctttc gaaggtatcg gtcggggcat tttgaacatt
    11821 gaaggattgc cggtgtacag agattctttt ggaggaatcg ggacaccgac aagcgaccac
    11881 gaacgtacga agatggatgt cgggactact catattctcg cgatagtcaa cgggtataac
    11941 ggaaaagagg gattaaagga agctgctgaa atgattcaat ccttactgag ggattatgcc
    12001 ggatcggatg gcggcgagct tatctatttt gaataataaa ggaatacatg aagaacatac
    12061 ttattttatt gacagtcctg cttttaccaa ctcttgctta tgcgcaaagt aaatcctctt
    12121 tttcttctat ggaggtgaat catgtacggg ttgctactcc cggacttttt gcgaaaagca
    12181 atcatatata tctgcatttg gattctttgc aagagcatga atatgctttt cccttaccgg
    12241 gagccaaagt tatttccgct tacggaactc gcggaggaca ttcgggagca gatataaaga
    12301 cgtgtgccaa agatacgatt cgtgctgctt ttgatggagt cgtacgtatg tcgaagccat
    12361 attatgctta cggaaatttg gttgtagtcc gtcatgcgaa cgggctggaa acgatttaca
    12421 gtcataactt caagaatttg gtacagagcg gagatacggt gaaagccgga caacctatcg
    12481 gactgaccgg acgtaccggc cgtgctacta cggagcatgt gcattttgaa acccgcatta
    12541 acggtca
//
