Select genomic region:
Overview
54.1
68.1
73.1
77.1
86.1

### Identified primary metabolite regions

c00054_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_54)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 54.1 | Rnf_complex,succinate2propionate | SCFA | 4,386 | 48,878 | Rnf complex C. sporogenes | RNF | 100%

c00068_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_68)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 68.1 | Pyruvate2acetate-formate | SCFA | 30,159 | 53,153 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

c00073_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_73)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 73.1 | acetate2butyrate | SCFA | 34,845 | 55,908 | Acetate to butyrate C. sporogenes | BUT | 83%

c00077_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_77)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 77.1 | Others_HGD_unassigned | Putative | 15,776 | 40,032 |

c00086_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_86)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 86.1 | Putrescine2spermidine | Aliphatic_amine | 22,913 | 38,457 | Putrescine2spermidine E. rectale | SPRM | 100%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 54.1 | Rnf_complex,succinate2propionate | SCFA | 4,386 | 48,878 | Rnf complex C. sporogenes | RNF | 100%
Region 68.1 | Pyruvate2acetate-formate | SCFA | 30,159 | 53,153 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%
Region 73.1 | acetate2butyrate | SCFA | 34,845 | 55,908 | Acetate to butyrate C. sporogenes | BUT | 83%
Region 77.1 | Others_HGD_unassigned | Putative | 15,776 | 40,032 |
Region 86.1 | Putrescine2spermidine | Aliphatic_amine | 22,913 | 38,457 | Putrescine2spermidine E. rectale | SPRM | 100%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_1)
  c00002_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_3)
  c00004_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_5)
  c00006_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_53)
  c00055_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_60)
  c00061_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_61)
  c00062_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_65)
  c00066_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_66)
  c00067_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_67)
  c00069_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_69)
  c00070_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_70)
  c00071_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_71)
  c00072_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_72)
  c00074_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_74)
  c00075_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_75)
  c00076_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_76)
  c00078_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_78)
  c00079_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_79)
  c00080_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_80)
  c00081_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_81)
  c00082_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_82)
  c00083_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_83)
  c00084_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_84)
  c00085_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_85)
  c00087_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_87)
  c00088_gnlPro.. (original name was: gnl|Prokka|HNBHGGCD_88)

Compact view
c00054_gnlPro.. - Region 1 - Rnf_complex,succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 4,386 - 48,878 nt. (total: 44,493 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00068_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 30,159 - 53,153 nt. (total: 22,995 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00073_gnlPro.. - Region 1 - acetate2butyrate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 34,845 - 55,908 nt. (total: 21,064 nt) Show pHMM detection rules used
Region on contig edge.
acetate2butyrate: (not (POR or POR_N or PFOR_II) and minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00077_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 15,776 - 40,032 nt. (total: 24,257 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00086_gnlPro.. - Region 1 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 22,913 - 38,457 nt. (total: 15,545 nt) Show pHMM detection rules used
Region on contig edge.
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.