## Sun Jun 30 12:22:53 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_018381175.1/GCA_018381175.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_018381175.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_018381175.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
AMEPOAEB_00001	657322.FPR_14560	1.63e-234	644.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,3WHMB@541000|Ruminococcaceae	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
AMEPOAEB_00002	657322.FPR_14570	3.46e-182	509.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,3WJGV@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AMEPOAEB_00003	748224.HMPREF9436_02843	2.32e-30	111.0	COG5652@1|root,COG5652@2|Bacteria,1VBNW@1239|Firmicutes,25827@186801|Clostridia,3WKKI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
AMEPOAEB_00004	657322.FPR_04780	7.33e-289	790.0	COG0285@1|root,COG0285@2|Bacteria	2|Bacteria	H	dihydrofolate synthase activity	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK,Mur_ligase_C,Mur_ligase_M
AMEPOAEB_00005	657322.FPR_04770	6.43e-66	201.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3WKRQ@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
AMEPOAEB_00006	657322.FPR_04760	9.26e-98	284.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3WJC6@541000|Ruminococcaceae	186801|Clostridia	T	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
AMEPOAEB_00008	657322.FPR_06560	0.0	895.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3WGI9@541000|Ruminococcaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
AMEPOAEB_00009	657322.FPR_09080	4.77e-230	636.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
AMEPOAEB_00010	748224.HMPREF9436_00078	5.98e-64	195.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
AMEPOAEB_00011	657322.FPR_09100	9.55e-88	258.0	COG0594@1|root,COG0594@2|Bacteria	2|Bacteria	J	ribonuclease P activity	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
AMEPOAEB_00012	657322.FPR_28890	4.7e-39	129.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3WKJ4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
AMEPOAEB_00013	657322.FPR_28900	1.82e-254	698.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
AMEPOAEB_00015	657322.FPR_19850	3.11e-145	426.0	COG0187@1|root,COG0187@2|Bacteria,1TQ6U@1239|Firmicutes,249NI@186801|Clostridia,3WH8Y@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
AMEPOAEB_00016	657322.FPR_21110	0.0	870.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,3WGKT@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
AMEPOAEB_00017	657322.FPR_21120	7.37e-251	688.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3WH7A@541000|Ruminococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
AMEPOAEB_00018	748224.HMPREF9436_01479	3.12e-191	556.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
AMEPOAEB_00019	657322.FPR_31430	4.97e-102	296.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WJWG@541000|Ruminococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
AMEPOAEB_00020	657322.FPR_31420	1.89e-228	628.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
AMEPOAEB_00021	657322.FPR_15780	4.47e-199	553.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3WIK3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
AMEPOAEB_00022	657322.FPR_15770	1.03e-94	280.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
AMEPOAEB_00023	411471.SUBVAR_07034	2.28e-180	519.0	COG3271@1|root,COG3271@2|Bacteria,1V1IQ@1239|Firmicutes,24FBU@186801|Clostridia,3WNEZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
AMEPOAEB_00024	411471.SUBVAR_06953	2.01e-55	186.0	COG5578@1|root,COG5578@2|Bacteria,1UK80@1239|Firmicutes,25FQ0@186801|Clostridia,3WM07@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
AMEPOAEB_00025	657322.FPR_25960	1.16e-34	126.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3WHKH@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
AMEPOAEB_00026	748224.HMPREF9436_02419	3.44e-132	375.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3WIAG@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
AMEPOAEB_00027	657322.FPR_25980	3.29e-191	530.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3WGGF@541000|Ruminococcaceae	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
AMEPOAEB_00028	657322.FPR_25990	2.56e-293	799.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3WGTW@541000|Ruminococcaceae	186801|Clostridia	F	AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
AMEPOAEB_00029	657322.FPR_26000	0.0	865.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3WGPD@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
AMEPOAEB_00030	657322.FPR_26010	0.0	2439.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
AMEPOAEB_00031	657322.FPR_26020	0.0	952.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
AMEPOAEB_00032	657322.FPR_26030	1.44e-164	460.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3WHTI@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
AMEPOAEB_00033	657322.FPR_26040	3.15e-255	700.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3WHDV@541000|Ruminococcaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
AMEPOAEB_00034	657322.FPR_26050	5.63e-177	493.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WGK4@541000|Ruminococcaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
AMEPOAEB_00035	657322.FPR_26060	1.51e-205	570.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3WHNT@541000|Ruminococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
AMEPOAEB_00036	657322.FPR_26070	6.12e-178	512.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
AMEPOAEB_00038	657322.FPR_26090	3.35e-290	796.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3WGHH@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
AMEPOAEB_00039	657322.FPR_26100	4.46e-193	536.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3WGWE@541000|Ruminococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
AMEPOAEB_00040	718252.FP2_32150	2.72e-14	74.7	COG2755@1|root,COG2755@2|Bacteria,1UM8B@1239|Firmicutes,25GBV@186801|Clostridia,3WRMU@541000|Ruminococcaceae	186801|Clostridia	E	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
AMEPOAEB_00041	748224.HMPREF9436_03164	1.64e-161	461.0	2DW9C@1|root,33Z5T@2|Bacteria,1VBX0@1239|Firmicutes,24Q8T@186801|Clostridia,3WQE2@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00042	657322.FPR_26130	1.1e-232	641.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3WIE9@541000|Ruminococcaceae	186801|Clostridia	D	Stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
AMEPOAEB_00043	657322.FPR_26140	0.0	926.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WGKI@541000|Ruminococcaceae	186801|Clostridia	C	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
AMEPOAEB_00044	748224.HMPREF9436_02872	3.56e-100	300.0	28S61@1|root,2ZEHJ@2|Bacteria,1W5F6@1239|Firmicutes,256VB@186801|Clostridia,3WQKF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00045	657322.FPR_24230	1.94e-80	241.0	COG0125@1|root,COG0125@2|Bacteria,1VI7E@1239|Firmicutes	1239|Firmicutes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,dNK
AMEPOAEB_00046	657322.FPR_24230	3.39e-32	116.0	COG0125@1|root,COG0125@2|Bacteria,1VI7E@1239|Firmicutes	1239|Firmicutes	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28,dNK
AMEPOAEB_00047	657322.FPR_24220	1.44e-231	638.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WH56@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AMEPOAEB_00048	748224.HMPREF9436_00016	1.15e-193	540.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WK10@541000|Ruminococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
AMEPOAEB_00049	718252.FP2_31120	3.3e-228	632.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIY9@541000|Ruminococcaceae	186801|Clostridia	P	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
AMEPOAEB_00050	657322.FPR_04810	1.04e-250	686.0	COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,2502I@186801|Clostridia,3WSPW@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AMEPOAEB_00051	657322.FPR_04820	0.0	981.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,3WHMM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
AMEPOAEB_00052	748224.HMPREF9436_00158	3.63e-78	249.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24M3C@186801|Clostridia,3WPC0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 9.97	epsJ2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AMEPOAEB_00053	657322.FPR_04840	0.0	1105.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,3WIMY@541000|Ruminococcaceae	186801|Clostridia	H	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
AMEPOAEB_00054	657322.FPR_04850	3.22e-157	439.0	COG1670@1|root,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia,3WJ7K@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
AMEPOAEB_00055	748224.HMPREF9436_02837	1.3e-282	775.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3WH00@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
AMEPOAEB_00056	657322.FPR_04880	1.32e-97	284.0	COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,24I1I@186801|Clostridia,3WJNW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
AMEPOAEB_00057	657322.FPR_04890	5.95e-113	326.0	2BVE9@1|root,32QU0@2|Bacteria,1V90X@1239|Firmicutes,24KRK@186801|Clostridia,3WQ96@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
AMEPOAEB_00058	748224.HMPREF9436_02438	3.8e-64	209.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia,3WJWF@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00059	718252.FP2_26400	2.96e-134	384.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,3WI2X@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_00060	748224.HMPREF9436_02436	3.26e-63	195.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,3WJT8@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
AMEPOAEB_00061	657322.FPR_04900	3.75e-242	665.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3WIR8@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
AMEPOAEB_00062	657322.FPR_04910	1.45e-187	524.0	2EC5R@1|root,3364D@2|Bacteria,1VGAK@1239|Firmicutes,24SS9@186801|Clostridia,3WKX9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00063	657322.FPR_04920	6.24e-78	231.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,3WK00@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
AMEPOAEB_00064	657322.FPR_04930	4.24e-37	124.0	COG1141@1|root,COG1141@2|Bacteria,1VGNV@1239|Firmicutes,259E5@186801|Clostridia,3WQRA@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
AMEPOAEB_00065	657322.FPR_04940	0.0	1653.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
AMEPOAEB_00066	657322.FPR_04950	9.48e-237	651.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3WGP5@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
AMEPOAEB_00067	657322.FPR_04960	7.16e-175	487.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,3WNRZ@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
AMEPOAEB_00068	657322.FPR_04970	2.12e-199	554.0	COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WG7J@541000|Ruminococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
AMEPOAEB_00069	657322.FPR_04980	0.0	1717.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3WH08@541000|Ruminococcaceae	186801|Clostridia	J	elongation factor G	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
AMEPOAEB_00070	411471.SUBVAR_05923	2.2e-62	191.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3WJB6@541000|Ruminococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
AMEPOAEB_00071	411471.SUBVAR_05922	3.97e-137	389.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WHH0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
AMEPOAEB_00072	411471.SUBVAR_05921	4.27e-130	371.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
AMEPOAEB_00073	411471.SUBVAR_05920	4.42e-57	177.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3WJVK@541000|Ruminococcaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
AMEPOAEB_00074	411471.SUBVAR_05919	2.05e-190	529.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
AMEPOAEB_00075	411471.SUBVAR_05918	1.42e-57	178.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WJ9F@541000|Ruminococcaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
AMEPOAEB_00076	411471.SUBVAR_05917	1.55e-68	207.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3WJ9K@541000|Ruminococcaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
AMEPOAEB_00077	411471.SUBVAR_05916	8.21e-155	436.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
AMEPOAEB_00078	411471.SUBVAR_05915	3.63e-95	278.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WIIZ@541000|Ruminococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
AMEPOAEB_00079	411471.SUBVAR_05914	9.81e-33	114.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
AMEPOAEB_00080	411471.SUBVAR_05913	1.01e-47	153.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
AMEPOAEB_00081	411471.SUBVAR_05912	6.26e-80	237.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3WITX@541000|Ruminococcaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
AMEPOAEB_00082	411471.SUBVAR_05911	7.91e-70	210.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WJBH@541000|Ruminococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
AMEPOAEB_00083	411471.SUBVAR_05910	1.33e-122	350.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
AMEPOAEB_00084	428125.CLOLEP_01023	3.44e-29	104.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3WKH5@541000|Ruminococcaceae	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
AMEPOAEB_00085	411471.SUBVAR_05908	7.34e-86	253.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3WIYN@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
AMEPOAEB_00086	411471.SUBVAR_05907	1.73e-115	332.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3WIFT@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
AMEPOAEB_00087	411471.SUBVAR_05906	1.96e-68	208.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WJ8R@541000|Ruminococcaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
AMEPOAEB_00088	411471.SUBVAR_05905	5.28e-103	299.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
AMEPOAEB_00089	411471.SUBVAR_05904	1.31e-32	113.0	COG1841@1|root,COG1841@2|Bacteria,1UG5U@1239|Firmicutes,24RUS@186801|Clostridia,3WKJT@541000|Ruminococcaceae	186801|Clostridia	J	ribosomal protein	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
AMEPOAEB_00090	411471.SUBVAR_05903	1.74e-87	258.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
AMEPOAEB_00091	411471.SUBVAR_05902	5.83e-239	665.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,3WG8Z@541000|Ruminococcaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
AMEPOAEB_00092	411471.SUBVAR_05901	1.97e-118	342.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WHQ6@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
AMEPOAEB_00093	411471.SUBVAR_05900	6.25e-171	478.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WGEW@541000|Ruminococcaceae	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
AMEPOAEB_00094	411471.SUBVAR_05899	7.16e-34	118.0	COG2163@1|root,COG2163@2|Bacteria,1UG5I@1239|Firmicutes,25ND3@186801|Clostridia,3WM9B@541000|Ruminococcaceae	186801|Clostridia	J	COG COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00095	411471.SUBVAR_05898	1.96e-49	157.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3WK1D@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
AMEPOAEB_00096	411471.SUBVAR_05897	1.19e-18	76.6	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia,3WM8G@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
AMEPOAEB_00097	411471.SUBVAR_05896	4.56e-78	233.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3WJ08@541000|Ruminococcaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
AMEPOAEB_00098	411471.SUBVAR_05895	7.55e-78	233.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
AMEPOAEB_00099	657322.FPR_11750	1.06e-111	324.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
AMEPOAEB_00100	411471.SUBVAR_05893	1.61e-204	568.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
AMEPOAEB_00101	411471.SUBVAR_05892	1.17e-64	198.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3WIRR@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
AMEPOAEB_00102	748224.HMPREF9436_02584	9.9e-207	580.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
AMEPOAEB_00103	411471.SUBVAR_05889	3.85e-288	792.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
AMEPOAEB_00105	411471.SUBVAR_05887	1.84e-281	771.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3WGF6@541000|Ruminococcaceae	186801|Clostridia	P	Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
AMEPOAEB_00106	411471.SUBVAR_05886	1.84e-43	142.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3WJXE@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
AMEPOAEB_00107	657322.FPR_09390	1.86e-270	738.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3WH61@541000|Ruminococcaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
AMEPOAEB_00109	657322.FPR_15820	2.76e-251	692.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
AMEPOAEB_00110	657322.FPR_15810	1.28e-137	390.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3WKZM@541000|Ruminococcaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
AMEPOAEB_00111	657322.FPR_15800	4.66e-92	270.0	COG3663@1|root,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,24HD8@186801|Clostridia,3WJEI@541000|Ruminococcaceae	186801|Clostridia	L	UreE urease accessory protein, C-terminal domain	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
AMEPOAEB_00112	742740.HMPREF9474_02911	0.0	1231.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,21YUA@1506553|Lachnoclostridium	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
AMEPOAEB_00113	537013.CLOSTMETH_02547	4.16e-24	91.7	2EQCT@1|root,33HYV@2|Bacteria,1VGI1@1239|Firmicutes,24W1G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00114	657322.FPR_29270	0.0	936.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia,3WIHF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
AMEPOAEB_00115	657322.FPR_29260	3.29e-121	348.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,3WH0B@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_00116	657322.FPR_16480	2e-89	265.0	COG1802@1|root,COG1802@2|Bacteria,1V5DF@1239|Firmicutes,24HJU@186801|Clostridia,3WRUX@541000|Ruminococcaceae	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
AMEPOAEB_00117	515620.EUBELI_00334	1.07e-139	399.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,24B3M@186801|Clostridia,25XGP@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AMEPOAEB_00118	657322.FPR_16490	5.39e-184	513.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3WHK4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
AMEPOAEB_00119	657322.FPR_16500	5.98e-37	132.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
AMEPOAEB_00120	411483.FAEPRAA2165_02858	1.76e-133	385.0	COG0031@1|root,COG0031@2|Bacteria,1VQV3@1239|Firmicutes,24XIE@186801|Clostridia,3WP2E@541000|Ruminococcaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	PALP
AMEPOAEB_00121	657322.FPR_06050	1.99e-299	819.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WHF4@541000|Ruminococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00122	657322.FPR_06040	2.7e-15	72.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3WGYU@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
AMEPOAEB_00123	748224.HMPREF9436_00871	7.07e-196	545.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WI0F@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
AMEPOAEB_00124	657322.FPR_20240	6.87e-181	506.0	COG0526@1|root,COG0526@2|Bacteria,1V7JP@1239|Firmicutes,25ET7@186801|Clostridia	186801|Clostridia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	AhpC-TSA,Redoxin
AMEPOAEB_00125	657322.FPR_20230	0.0	1674.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3WGZA@541000|Ruminococcaceae	186801|Clostridia	M	peptidoglycan binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,SpoIID
AMEPOAEB_00126	657322.FPR_20220	2.61e-170	474.0	COG3409@1|root,COG3409@2|Bacteria,1V14F@1239|Firmicutes,24ASJ@186801|Clostridia,3WK7I@541000|Ruminococcaceae	186801|Clostridia	M	peptidoglycan binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
AMEPOAEB_00127	657322.FPR_20210	9.28e-113	323.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,3WIVQ@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
AMEPOAEB_00128	657322.FPR_20200	1.54e-223	617.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3WG9C@541000|Ruminococcaceae	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
AMEPOAEB_00130	657322.FPR_20180	2.14e-174	486.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3WGSY@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
AMEPOAEB_00131	748224.HMPREF9436_00863	3.18e-85	253.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,3WSQI@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
AMEPOAEB_00132	657322.FPR_20160	4.04e-204	564.0	COG3947@1|root,COG3947@2|Bacteria,1URI4@1239|Firmicutes,24GP6@186801|Clostridia,3WJC3@541000|Ruminococcaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
AMEPOAEB_00133	657322.FPR_20140	8.84e-43	139.0	COG4877@1|root,COG4877@2|Bacteria,1VEY1@1239|Firmicutes,24MV0@186801|Clostridia,3WKKV@541000|Ruminococcaceae	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like,RHH_5
AMEPOAEB_00134	657322.FPR_20130	1.01e-230	637.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,248UU@186801|Clostridia,3WI4C@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
AMEPOAEB_00135	657322.FPR_20120	6.19e-283	775.0	COG2379@1|root,COG2379@2|Bacteria,1TSQH@1239|Firmicutes,249XX@186801|Clostridia,3WGPY@541000|Ruminococcaceae	186801|Clostridia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
AMEPOAEB_00137	657322.FPR_20110	5.36e-291	793.0	COG2173@1|root,COG3807@1|root,COG2173@2|Bacteria,COG3807@2|Bacteria,1VMR7@1239|Firmicutes	1239|Firmicutes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15,SH3_3,SH3_4,VanY
AMEPOAEB_00139	657322.FPR_20090	5.78e-69	215.0	28QE7@1|root,2ZCWI@2|Bacteria,1W2JK@1239|Firmicutes,24QIX@186801|Clostridia	186801|Clostridia	S	No similarity found	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00140	1280685.AUKC01000025_gene1064	1.04e-26	118.0	COG0457@1|root,COG0457@2|Bacteria,1V0II@1239|Firmicutes,24C9M@186801|Clostridia,4C0C1@830|Butyrivibrio	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	ALGX,DHHW
AMEPOAEB_00141	657322.FPR_20070	0.0	933.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
AMEPOAEB_00143	471875.RUMLAC_01470	2.68e-09	64.7	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_2,Pkinase,TPR_16,TPR_8
AMEPOAEB_00144	657322.FPR_20020	1e-22	87.4	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
AMEPOAEB_00145	657322.FPR_19860	2.89e-114	348.0	COG0188@1|root,COG0188@2|Bacteria,1TPPU@1239|Firmicutes,24CU3@186801|Clostridia,3WG8X@541000|Ruminococcaceae	186801|Clostridia	L	PFAM DNA gyrase topoisomerase IV, subunit A	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
AMEPOAEB_00146	657322.FPR_19870	3.23e-103	299.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
AMEPOAEB_00147	657322.FPR_19880	7.14e-192	533.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
AMEPOAEB_00148	411471.SUBVAR_04451	5.22e-41	136.0	2AF03@1|root,314Y6@2|Bacteria,1V9HG@1239|Firmicutes,25CY9@186801|Clostridia,3WKPF@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
AMEPOAEB_00149	411471.SUBVAR_04450	1e-142	402.0	COG0175@1|root,COG0175@2|Bacteria,1UZK3@1239|Firmicutes,24CWM@186801|Clostridia,3WMXJ@541000|Ruminococcaceae	186801|Clostridia	EH	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
AMEPOAEB_00150	411471.SUBVAR_04449	2.2e-247	689.0	COG0791@1|root,COG0791@2|Bacteria,1UK7M@1239|Firmicutes,25FPF@186801|Clostridia,3WK4A@541000|Ruminococcaceae	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
AMEPOAEB_00152	657322.FPR_02270	9.13e-183	512.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
AMEPOAEB_00154	748224.HMPREF9436_01395	0.0	1013.0	COG1783@1|root,COG1783@2|Bacteria,1TT85@1239|Firmicutes,24ETQ@186801|Clostridia,3WPQU@541000|Ruminococcaceae	186801|Clostridia	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
AMEPOAEB_00155	411471.SUBVAR_06102	1.97e-14	71.6	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
AMEPOAEB_00156	657322.FPR_25870	2.99e-173	484.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
AMEPOAEB_00158	657322.FPR_25530	4.26e-261	719.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3WHQA@541000|Ruminococcaceae	186801|Clostridia	H	Carbohydrate kinase, FGGY family protein	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
AMEPOAEB_00161	748224.HMPREF9436_01428	4.48e-99	292.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WG7F@541000|Ruminococcaceae	186801|Clostridia	P	Metal cation transporter, ZIP family	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
AMEPOAEB_00162	657322.FPR_28830	2.05e-132	386.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00163	657322.FPR_11110	1.59e-174	493.0	2DNZ4@1|root,32ZV4@2|Bacteria,1VGWE@1239|Firmicutes,24QUP@186801|Clostridia,3WIIM@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00164	657322.FPR_11120	1.2e-130	374.0	2EFRU@1|root,339HT@2|Bacteria,1VJRN@1239|Firmicutes,24WAI@186801|Clostridia,3WMDS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
AMEPOAEB_00165	748224.HMPREF9436_02494	2.01e-154	440.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
AMEPOAEB_00166	718252.FP2_26780	1.27e-187	525.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
AMEPOAEB_00167	657322.FPR_17210	1.18e-155	437.0	COG5578@1|root,COG5578@2|Bacteria,1V81E@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
AMEPOAEB_00168	657322.FPR_17220	1.44e-77	241.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,24A1K@186801|Clostridia,3WGPI@541000|Ruminococcaceae	186801|Clostridia	F	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
AMEPOAEB_00169	748224.HMPREF9436_03335	5.46e-152	430.0	29MEK@1|root,308CG@2|Bacteria,1U37V@1239|Firmicutes,24B5H@186801|Clostridia,3WI9A@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00172	718252.FP2_06630	2.64e-69	212.0	2C38D@1|root,31M9W@2|Bacteria,1V6Q7@1239|Firmicutes,24MA6@186801|Clostridia,3WKZX@541000|Ruminococcaceae	186801|Clostridia	S	Minor capsid protein	-	-	-	-	-	-	-	-	-	-	-	-	Minor_capsid_2
AMEPOAEB_00173	657322.FPR_27880	5.3e-104	300.0	COG4978@1|root,COG4978@2|Bacteria,1VFVB@1239|Firmicutes,24P4E@186801|Clostridia,3WQ9A@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00174	657322.FPR_27890	2.67e-316	876.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,3WI0H@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type bacteriocin transporter	-	-	-	ko:K20344	ko02010,ko02024,map02010,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
AMEPOAEB_00175	657322.FPR_28370	1.27e-179	501.0	COG1712@1|root,COG1712@2|Bacteria,1V2MT@1239|Firmicutes,25D3V@186801|Clostridia	186801|Clostridia	S	homoserine dehydrogenase	-	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
AMEPOAEB_00177	657322.FPR_03990	4.8e-219	610.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WGRD@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
AMEPOAEB_00178	97138.C820_00139	1.16e-25	103.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,36GJ7@31979|Clostridiaceae	186801|Clostridia	K	lacI family	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
AMEPOAEB_00179	742733.HMPREF9469_04512	9.86e-290	808.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,21Z7B@1506553|Lachnoclostridium	186801|Clostridia	G	phosphotransferase system, EIIB	-	-	2.7.1.208	ko:K20107,ko:K20108	ko00500,ko02060,map00500,map02060	M00806	R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.11,4.A.1.1.12	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
AMEPOAEB_00180	657322.FPR_12890	4.93e-56	182.0	COG1149@1|root,COG2878@1|root,COG1149@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3WIFS@541000|Ruminococcaceae	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
AMEPOAEB_00181	748224.HMPREF9436_02194	6.07e-182	511.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
AMEPOAEB_00182	657322.FPR_20290	3.8e-224	616.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3WK1R@541000|Ruminococcaceae	186801|Clostridia	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
AMEPOAEB_00183	657322.FPR_20280	3.53e-214	595.0	COG5002@1|root,COG5002@2|Bacteria,1TS83@1239|Firmicutes,249CD@186801|Clostridia,3WHFA@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
AMEPOAEB_00184	657322.FPR_03680	2.97e-138	421.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3WG8U@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
AMEPOAEB_00186	657322.FPR_12460	9.44e-183	508.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3WGPJ@541000|Ruminococcaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
AMEPOAEB_00187	657322.FPR_12470	1.92e-119	361.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3WGGK@541000|Ruminococcaceae	186801|Clostridia	C	TIGRFAM formate acetyltransferase	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
AMEPOAEB_00188	657322.FPR_29370	6.2e-129	365.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24KJU@186801|Clostridia	186801|Clostridia	M	acetyltransferase (GNAT) family	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
AMEPOAEB_00189	657322.FPR_29380	2.43e-265	725.0	COG0657@1|root,COG0657@2|Bacteria,1U1GT@1239|Firmicutes,24E51@186801|Clostridia,3WM2Q@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
AMEPOAEB_00190	718252.FP2_18630	1.07e-225	636.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
AMEPOAEB_00191	657322.FPR_29410	1.65e-265	733.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,3WHCS@541000|Ruminococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
AMEPOAEB_00192	657322.FPR_29420	1.1e-278	762.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5,Lactamase_B
AMEPOAEB_00194	748224.HMPREF9436_02963	1.2e-281	781.0	COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia,3WIM7@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter, substrate-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
AMEPOAEB_00195	657322.FPR_29440	0.0	926.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3WG85@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
AMEPOAEB_00196	748224.HMPREF9436_02966	1.22e-129	374.0	2BBZZ@1|root,325IJ@2|Bacteria,1URJQ@1239|Firmicutes,259G0@186801|Clostridia,3WQ3T@541000|Ruminococcaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
AMEPOAEB_00197	657322.FPR_29460	1.33e-312	850.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3WGF6@541000|Ruminococcaceae	186801|Clostridia	P	Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
AMEPOAEB_00198	657322.FPR_29470	1.37e-99	289.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3WII3@541000|Ruminococcaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
AMEPOAEB_00199	657322.FPR_29480	1.01e-290	795.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
AMEPOAEB_00200	657322.FPR_29490	2.21e-184	513.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
AMEPOAEB_00201	657322.FPR_29500	2.29e-183	511.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3WGT7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
AMEPOAEB_00203	748224.HMPREF9436_02975	1.07e-107	313.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3WJ60@541000|Ruminococcaceae	186801|Clostridia	K	dihydroxyacetone kinase regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
AMEPOAEB_00204	657322.FPR_29530	0.0	985.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
AMEPOAEB_00205	657322.FPR_09310	5.04e-296	809.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WIT9@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
AMEPOAEB_00206	657322.FPR_02930	6.16e-55	188.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
AMEPOAEB_00207	718252.FP2_26960	3.39e-17	73.9	28ZHZ@1|root,2ZM9E@2|Bacteria,1W50Q@1239|Firmicutes,255D3@186801|Clostridia,3WR9B@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00208	657322.FPR_02950	1.67e-80	239.0	COG1321@1|root,COG1321@2|Bacteria,1VH4R@1239|Firmicutes,24SPR@186801|Clostridia,3WMMY@541000|Ruminococcaceae	186801|Clostridia	K	Iron dependent repressor, N-terminal DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repress,MarR_2
AMEPOAEB_00209	657322.FPR_02960	3.31e-139	399.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	envE	-	3.1.4.46,3.2.1.18,3.2.1.8	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	-	R01030,R01470,R04018	RC00017,RC00028,RC00077,RC00425	ko00000,ko00001,ko01000,ko02042	-	GH33	-	GHL10,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin,SLH
AMEPOAEB_00210	657322.FPR_09350	2e-156	438.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3WH2K@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase small domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
AMEPOAEB_00211	657322.FPR_09360	8.06e-17	73.2	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3WMHU@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
AMEPOAEB_00212	657322.FPR_09370	1.31e-117	342.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3WHA4@541000|Ruminococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
AMEPOAEB_00213	748224.HMPREF9436_01396	2.61e-313	863.0	28I8J@1|root,2Z8BD@2|Bacteria,1UBQ6@1239|Firmicutes,24DZA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00214	742738.HMPREF9460_04047	1.29e-36	132.0	COG3935@1|root,COG3935@2|Bacteria,1VAP8@1239|Firmicutes	1239|Firmicutes	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00215	748224.HMPREF9436_01398	2.14e-264	729.0	COG2868@1|root,COG2868@2|Bacteria,1VC0X@1239|Firmicutes,24N84@186801|Clostridia	186801|Clostridia	J	Cysteine protease Prp	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Prp
AMEPOAEB_00217	748224.HMPREF9436_01968	2.95e-117	335.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,3WIS5@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
AMEPOAEB_00218	657322.FPR_11040	5.04e-132	375.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
AMEPOAEB_00219	657322.FPR_02110	4.92e-148	416.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WS6N@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
AMEPOAEB_00220	657322.FPR_02100	3.5e-146	413.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
AMEPOAEB_00221	657322.FPR_25700	8.67e-256	703.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3WHPY@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
AMEPOAEB_00222	657322.FPR_25710	1.33e-100	298.0	COG0524@1|root,COG0524@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,3WMTE@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	-	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
AMEPOAEB_00223	657322.FPR_16260	2.46e-62	193.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3WIJW@541000|Ruminococcaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
AMEPOAEB_00224	657322.FPR_16270	0.0	1001.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3WH32@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
AMEPOAEB_00225	657322.FPR_21500	0.0	1143.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3WH8K@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	ydcP	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
AMEPOAEB_00227	1140001.I571_01814	3.55e-25	101.0	2DHKB@1|root,32U9C@2|Bacteria,1VBER@1239|Firmicutes,4IBXY@91061|Bacilli,4B4BU@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00229	657322.FPR_05430	2.07e-144	419.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3WHJQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
AMEPOAEB_00230	657322.FPR_13730	2.11e-243	672.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
AMEPOAEB_00231	657322.FPR_27870	5.85e-213	592.0	COG0845@1|root,COG0845@2|Bacteria,1V5WK@1239|Firmicutes,25D23@186801|Clostridia,3WNT3@541000|Ruminococcaceae	186801|Clostridia	M	HlyD family secretion protein	-	-	-	ko:K20345	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	3.A.1.112,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3
AMEPOAEB_00232	657322.FPR_24250	8.93e-100	290.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJAP@541000|Ruminococcaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
AMEPOAEB_00233	657322.FPR_24260	4.49e-60	185.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3WK85@541000|Ruminococcaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
AMEPOAEB_00234	657322.FPR_24270	8.92e-271	743.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,3WHPA@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
AMEPOAEB_00235	657322.FPR_24280	2.97e-211	583.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,3WH3P@541000|Ruminococcaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
AMEPOAEB_00236	657322.FPR_24290	9.17e-241	661.0	2E0TS@1|root,32WBE@2|Bacteria,1VBFI@1239|Firmicutes,24PTN@186801|Clostridia,3WIIS@541000|Ruminococcaceae	186801|Clostridia	S	Prokaryotic RING finger family 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF2628,Prok-RING_1
AMEPOAEB_00237	657322.FPR_24300	3.32e-263	721.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3WG91@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
AMEPOAEB_00238	657322.FPR_24310	5.79e-288	787.0	COG3975@1|root,COG3975@2|Bacteria,1UHV7@1239|Firmicutes,25E3Y@186801|Clostridia,3WSNP@541000|Ruminococcaceae	186801|Clostridia	S	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
AMEPOAEB_00239	657322.FPR_24320	1.68e-177	494.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia,3WSIK@541000|Ruminococcaceae	186801|Clostridia	K	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
AMEPOAEB_00240	657322.FPR_24340	0.0	881.0	COG3064@1|root,COG3064@2|Bacteria,1VASR@1239|Firmicutes,24IM3@186801|Clostridia	186801|Clostridia	M	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
AMEPOAEB_00241	657322.FPR_24350	6.63e-173	482.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,3WGU3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
AMEPOAEB_00242	657322.FPR_24360	6.61e-167	466.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3WGUN@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
AMEPOAEB_00243	657322.FPR_24370	1.04e-117	338.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WIRX@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
AMEPOAEB_00244	657322.FPR_24380	1.98e-173	483.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3WGF5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
AMEPOAEB_00245	657322.FPR_24390	1.44e-195	543.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3WH2Z@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
AMEPOAEB_00246	657322.FPR_24400	2.68e-274	750.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
AMEPOAEB_00247	657322.FPR_24410	3.66e-254	698.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
AMEPOAEB_00250	657322.FPR_16760	2.38e-295	805.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3WGV4@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
AMEPOAEB_00251	657322.FPR_21570	4.06e-93	271.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3WII3@541000|Ruminococcaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
AMEPOAEB_00252	657322.FPR_21580	1.05e-115	332.0	COG0482@1|root,COG0482@2|Bacteria	2|Bacteria	J	sulfurtransferase activity	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
AMEPOAEB_00253	657322.FPR_21590	1.7e-115	330.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,3WISH@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
AMEPOAEB_00254	657322.FPR_09290	1.44e-208	579.0	COG0470@1|root,COG0470@2|Bacteria,1V7FD@1239|Firmicutes,24NVX@186801|Clostridia,3WIJC@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
AMEPOAEB_00255	657322.FPR_09300	1.66e-20	87.8	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,3WK0Y@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
AMEPOAEB_00256	657322.FPR_19580	1.69e-55	192.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGE7@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
AMEPOAEB_00257	657322.FPR_19570	8.04e-192	533.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3WGSS@541000|Ruminococcaceae	186801|Clostridia	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
AMEPOAEB_00258	657322.FPR_03900	1.59e-115	331.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3WK62@541000|Ruminococcaceae	186801|Clostridia	S	Mitochondrial PGP phosphatase	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
AMEPOAEB_00259	748224.HMPREF9436_02340	9.94e-186	518.0	COG0648@1|root,COG0648@2|Bacteria,1UZNN@1239|Firmicutes,24A1E@186801|Clostridia,3WH4K@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV	Nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
AMEPOAEB_00260	657322.FPR_25260	0.0	1126.0	COG4225@1|root,COG4225@2|Bacteria,1UXGZ@1239|Firmicutes,25D7M@186801|Clostridia	186801|Clostridia	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
AMEPOAEB_00261	657322.FPR_02040	9.29e-164	469.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia,3WI0S@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
AMEPOAEB_00262	658655.HMPREF0988_02502	1.34e-07	57.4	COG2188@1|root,COG3393@1|root,COG2188@2|Bacteria,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	ymfC	-	-	ko:K03710,ko:K06976	-	-	-	-	ko00000,ko03000	-	-	-	Acetyltransf_1,Acetyltransf_9,FR47,GNAT_acetyltran,GntR,UTRA
AMEPOAEB_00263	657322.FPR_12590	0.0	868.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
AMEPOAEB_00264	657322.FPR_05860	1.72e-315	859.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3WGUY@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
AMEPOAEB_00265	657322.FPR_05870	1.4e-147	416.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
AMEPOAEB_00266	657322.FPR_05880	2.37e-183	511.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3WGUI@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
AMEPOAEB_00267	657322.FPR_05890	6.18e-115	330.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3WJFT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
AMEPOAEB_00268	657322.FPR_05900	0.0	1691.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3WGK9@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyltransferase family 36	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
AMEPOAEB_00269	657322.FPR_05910	8.83e-242	664.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,3WGP8@541000|Ruminococcaceae	186801|Clostridia	K	sugar-binding domain protein	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
AMEPOAEB_00270	657322.FPR_05920	0.0	914.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
AMEPOAEB_00271	657322.FPR_05930	3.83e-231	636.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3WHS2@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AMEPOAEB_00272	657322.FPR_05940	2.67e-192	535.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3WH4R@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AMEPOAEB_00273	657322.FPR_05950	1.35e-92	270.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,3WJTP@541000|Ruminococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
AMEPOAEB_00274	748224.HMPREF9436_01849	1.65e-57	191.0	COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,248I0@186801|Clostridia,3WI3G@541000|Ruminococcaceae	186801|Clostridia	E	Component of the transport system for branched-chain amino acids	brnQ	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
AMEPOAEB_00275	657322.FPR_05970	9.19e-168	470.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3WIHB@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
AMEPOAEB_00276	657322.FPR_05980	2.54e-132	375.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3WK2M@541000|Ruminococcaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
AMEPOAEB_00277	657322.FPR_05990	4.67e-50	169.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
AMEPOAEB_00278	748224.HMPREF9436_01064	9.45e-100	294.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3WHF8@541000|Ruminococcaceae	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
AMEPOAEB_00279	657322.FPR_09200	5.86e-157	441.0	COG1802@1|root,COG1802@2|Bacteria,1V90H@1239|Firmicutes,24B32@186801|Clostridia,3WQIB@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K22293	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
AMEPOAEB_00280	657322.FPR_09190	1.14e-86	258.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3WJ0X@541000|Ruminococcaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
AMEPOAEB_00282	657322.FPR_03510	2.29e-48	154.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,24QV3@186801|Clostridia,3WKST@541000|Ruminococcaceae	186801|Clostridia	S	Transcriptional Coactivator p15 (PC4)	-	-	-	-	-	-	-	-	-	-	-	-	PC4
AMEPOAEB_00283	748224.HMPREF9436_02388	7.32e-132	374.0	COG3481@1|root,COG3481@2|Bacteria,1TQEK@1239|Firmicutes,24BRR@186801|Clostridia,3WIKZ@541000|Ruminococcaceae	186801|Clostridia	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
AMEPOAEB_00284	657322.FPR_03490	1.57e-88	260.0	2AIN5@1|root,3194H@2|Bacteria,1V6U3@1239|Firmicutes,24JK0@186801|Clostridia,3WJU6@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3842
AMEPOAEB_00285	657322.FPR_03480	0.0	925.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3WHQP@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
AMEPOAEB_00286	657322.FPR_03470	4.26e-108	311.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,3WJEQ@541000|Ruminococcaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
AMEPOAEB_00287	657322.FPR_03460	1.52e-188	522.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3WGQM@541000|Ruminococcaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
AMEPOAEB_00288	657322.FPR_03450	0.0	874.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WHZE@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00289	657322.FPR_03430	1.36e-304	832.0	2DB7E@1|root,2Z7KT@2|Bacteria,1V0PC@1239|Firmicutes,24D3B@186801|Clostridia,3WIEU@541000|Ruminococcaceae	186801|Clostridia	S	Penicillin-binding protein Tp47 domain a	-	-	-	-	-	-	-	-	-	-	-	-	DUF1533,PBP-Tp47_a,PBP-Tp47_c
AMEPOAEB_00290	657322.FPR_03420	9.73e-215	598.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,3WH19@541000|Ruminococcaceae	186801|Clostridia	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
AMEPOAEB_00291	657322.FPR_03410	1.09e-93	275.0	COG3976@1|root,COG3976@2|Bacteria,1VENM@1239|Firmicutes,24RRX@186801|Clostridia,3WM0V@541000|Ruminococcaceae	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
AMEPOAEB_00292	657322.FPR_03400	6.2e-210	580.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WIWA@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
AMEPOAEB_00293	657322.FPR_03390	0.0	1288.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3WHGR@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
AMEPOAEB_00294	657322.FPR_03380	5.62e-55	172.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3WKHQ@541000|Ruminococcaceae	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00295	657322.FPR_03370	5.09e-301	824.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WG82@541000|Ruminococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
AMEPOAEB_00296	411483.FAEPRAA2165_00432	3.73e-84	260.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3WHZ5@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
AMEPOAEB_00297	657322.FPR_18160	3.6e-30	107.0	28ZEN@1|root,2ZM68@2|Bacteria,1W2T3@1239|Firmicutes,257D2@186801|Clostridia,3WRA6@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00298	748224.HMPREF9436_02018	2.61e-208	580.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
AMEPOAEB_00299	657322.FPR_14580	4.72e-160	447.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
AMEPOAEB_00300	657322.FPR_14590	3.81e-151	426.0	COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,24EKV@186801|Clostridia,3WM22@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
AMEPOAEB_00301	657322.FPR_27670	0.0	1376.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WI09@541000|Ruminococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
AMEPOAEB_00302	657322.FPR_27660	6.49e-244	679.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3WPUP@541000|Ruminococcaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
AMEPOAEB_00303	657322.FPR_27650	0.0	1038.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3WGFA@541000|Ruminococcaceae	186801|Clostridia	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
AMEPOAEB_00304	657322.FPR_27640	1.58e-301	823.0	COG4856@1|root,COG4856@2|Bacteria,1V9AC@1239|Firmicutes,25Q6T@186801|Clostridia,3WHS9@541000|Ruminococcaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
AMEPOAEB_00305	657322.FPR_27630	1.11e-206	572.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
AMEPOAEB_00306	657322.FPR_27620	2.67e-272	746.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WITA@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
AMEPOAEB_00307	657322.FPR_27610	0.0	1110.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
AMEPOAEB_00309	657322.FPR_27590	0.0	988.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
AMEPOAEB_00310	657322.FPR_27580	2.74e-303	827.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia,3WM35@541000|Ruminococcaceae	186801|Clostridia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
AMEPOAEB_00311	657322.FPR_27570	1.5e-110	317.0	COG0454@1|root,COG0456@2|Bacteria,1V1VV@1239|Firmicutes,25CUX@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
AMEPOAEB_00312	657322.FPR_12610	1.27e-251	689.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3WHV3@541000|Ruminococcaceae	186801|Clostridia	E	aspartate-ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
AMEPOAEB_00313	657322.FPR_12600	2.26e-95	283.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,25B4M@186801|Clostridia,3WRIV@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
AMEPOAEB_00314	657322.FPR_05060	2.12e-225	620.0	COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,1UK9F@1239|Firmicutes,25FRE@186801|Clostridia,3WSPZ@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
AMEPOAEB_00315	657322.FPR_05070	8.35e-161	451.0	COG2746@1|root,COG2746@2|Bacteria,1TT5E@1239|Firmicutes,25CER@186801|Clostridia,3WK3S@541000|Ruminococcaceae	186801|Clostridia	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
AMEPOAEB_00316	748224.HMPREF9436_02663	6.57e-36	138.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WHMA@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
AMEPOAEB_00317	748224.HMPREF9436_02665	4.4e-118	344.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_c3_2,FAD_binding_2,FAD_oxidored
AMEPOAEB_00318	903814.ELI_2825	2.38e-35	136.0	COG0583@1|root,COG0583@2|Bacteria,1V09D@1239|Firmicutes,24H18@186801|Clostridia,25ZRW@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AMEPOAEB_00319	1232443.BAIA02000103_gene2908	8.42e-286	793.0	COG3451@1|root,COG3451@2|Bacteria,1TS2J@1239|Firmicutes,25EI6@186801|Clostridia,26AGB@186813|unclassified Clostridiales	186801|Clostridia	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
AMEPOAEB_00320	411471.SUBVAR_04465	5.69e-19	83.2	COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,24C3A@186801|Clostridia,3WJ2E@541000|Ruminococcaceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
AMEPOAEB_00321	411471.SUBVAR_04466	2.23e-77	230.0	2DMEJ@1|root,32R02@2|Bacteria,1V7K0@1239|Firmicutes,24S6R@186801|Clostridia,3WMRG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00322	657322.FPR_20730	1.22e-216	598.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
AMEPOAEB_00323	748224.HMPREF9436_00932	1.98e-303	845.0	COG3583@1|root,COG4942@1|root,COG3583@2|Bacteria,COG4942@2|Bacteria,1UK5Q@1239|Firmicutes,25FKW@186801|Clostridia	186801|Clostridia	D	G5	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
AMEPOAEB_00324	657322.FPR_20750	3.53e-168	470.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3WHNA@541000|Ruminococcaceae	186801|Clostridia	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
AMEPOAEB_00325	657322.FPR_20760	1.3e-99	289.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
AMEPOAEB_00326	657322.FPR_20770	3.04e-260	716.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,3WJKQ@541000|Ruminococcaceae	186801|Clostridia	S	basic membrane	tmpC	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
AMEPOAEB_00327	748224.HMPREF9436_00937	0.0	948.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
AMEPOAEB_00328	657322.FPR_20790	1.06e-258	711.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHM5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
AMEPOAEB_00329	657322.FPR_20800	7.42e-203	563.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WHCN@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
AMEPOAEB_00330	657322.FPR_20810	1.02e-145	413.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,3WJVW@541000|Ruminococcaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
AMEPOAEB_00331	657322.FPR_20820	2.97e-168	471.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,3WI2V@541000|Ruminococcaceae	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA,Wzz
AMEPOAEB_00332	657322.FPR_20830	1.34e-182	507.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3WK04@541000|Ruminococcaceae	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
AMEPOAEB_00333	657322.FPR_20840	5.74e-136	390.0	2BCB7@1|root,325WH@2|Bacteria,1VU5S@1239|Firmicutes	657322.FPR_20840|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00336	657322.FPR_28910	5.76e-33	122.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
AMEPOAEB_00337	657322.FPR_28920	8.34e-132	375.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WK2C@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
AMEPOAEB_00338	748224.HMPREF9436_01249	4.76e-100	296.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,3WKAS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
AMEPOAEB_00339	657322.FPR_30060	0.0	1287.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3WSDQ@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
AMEPOAEB_00340	657322.FPR_30050	1.04e-64	197.0	COG1873@1|root,COG1873@2|Bacteria,1TUA5@1239|Firmicutes,259AT@186801|Clostridia,3WMB7@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein, YlmC YmxH family	-	-	-	-	-	-	-	-	-	-	-	-	PRC
AMEPOAEB_00341	657322.FPR_30040	7.56e-148	416.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3WKIQ@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
AMEPOAEB_00342	657322.FPR_30030	2.31e-34	117.0	291XB@1|root,2ZPGX@2|Bacteria,1W4VH@1239|Firmicutes,255C3@186801|Clostridia,3WQUH@541000|Ruminococcaceae	186801|Clostridia	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
AMEPOAEB_00343	657322.FPR_30020	3.55e-99	287.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3WJGD@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
AMEPOAEB_00344	718252.FP2_06210	7.66e-116	338.0	COG3503@1|root,COG3503@2|Bacteria,1V8H3@1239|Firmicutes,24JRC@186801|Clostridia,3WJIA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
AMEPOAEB_00345	657322.FPR_30000	3.45e-305	830.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3WGFB@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
AMEPOAEB_00346	657322.FPR_29990	5.74e-235	650.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,3WHZ1@541000|Ruminococcaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
AMEPOAEB_00347	657322.FPR_29980	2.13e-189	526.0	2F8HG@1|root,340WA@2|Bacteria,1VXQT@1239|Firmicutes,2529I@186801|Clostridia,3WPPF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00348	657322.FPR_29970	6.41e-163	455.0	COG0125@1|root,COG0125@2|Bacteria,1V2D5@1239|Firmicutes,25CJJ@186801|Clostridia,3WIE4@541000|Ruminococcaceae	186801|Clostridia	F	thymidylate kinase	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
AMEPOAEB_00349	657322.FPR_29960	2.69e-182	507.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,3WGNR@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
AMEPOAEB_00350	657322.FPR_29950	0.0	1670.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
AMEPOAEB_00351	657322.FPR_29940	2.05e-131	372.0	COG0454@1|root,COG0456@2|Bacteria,1VGZX@1239|Firmicutes,24I40@186801|Clostridia,3WMBR@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
AMEPOAEB_00352	1140001.I571_01812	8.01e-29	114.0	COG1196@1|root,COG1196@2|Bacteria,1TSKM@1239|Firmicutes,4I7Z5@91061|Bacilli,4B103@81852|Enterococcaceae	91061|Bacilli	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
AMEPOAEB_00353	552396.HMPREF0863_02438	2.25e-33	125.0	28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes,3VQ9J@526524|Erysipelotrichia	526524|Erysipelotrichia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
AMEPOAEB_00354	645991.Sgly_0321	3.18e-79	250.0	28HHC@1|root,2Z7T2@2|Bacteria,1TR3B@1239|Firmicutes,24D5P@186801|Clostridia	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
AMEPOAEB_00355	1140001.I571_01814	1.26e-25	102.0	2DHKB@1|root,32U9C@2|Bacteria,1VBER@1239|Firmicutes,4IBXY@91061|Bacilli,4B4BU@81852|Enterococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00356	657322.FPR_09950	3.82e-180	501.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3WGH2@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
AMEPOAEB_00357	657322.FPR_09940	2.12e-128	369.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3WGN2@541000|Ruminococcaceae	186801|Clostridia	P	phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
AMEPOAEB_00358	748224.HMPREF9436_02140	1.61e-153	432.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3WIJ0@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
AMEPOAEB_00359	657322.FPR_00430	5.24e-193	536.0	2DCDQ@1|root,2ZDSD@2|Bacteria,1V33B@1239|Firmicutes,25BJU@186801|Clostridia,3WMNK@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
AMEPOAEB_00360	657322.FPR_26360	1.55e-54	176.0	COG4200@1|root,COG4200@2|Bacteria,1TSD5@1239|Firmicutes,24DU9@186801|Clostridia,3WJ80@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
AMEPOAEB_00361	657322.FPR_26350	4.73e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3WJYM@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
AMEPOAEB_00362	657322.FPR_26340	0.0	912.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WGVH@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
AMEPOAEB_00363	657322.FPR_26330	4.38e-209	578.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WHJU@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
AMEPOAEB_00364	657322.FPR_26320	0.0	1123.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
AMEPOAEB_00365	657322.FPR_26310	1.57e-95	280.0	COG0711@1|root,COG0711@2|Bacteria,1VEI8@1239|Firmicutes	1239|Firmicutes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
AMEPOAEB_00366	657322.FPR_26300	2.19e-38	129.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WKSD@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
AMEPOAEB_00367	657322.FPR_26290	6.8e-151	425.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3WIAV@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
AMEPOAEB_00368	657322.FPR_26270	5.47e-103	298.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3WK7E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
AMEPOAEB_00372	657322.FPR_26230	3.71e-64	196.0	2CG7V@1|root,32S3C@2|Bacteria,1UIG6@1239|Firmicutes,25EMK@186801|Clostridia,3WRBV@541000|Ruminococcaceae	186801|Clostridia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4298,Dabb
AMEPOAEB_00373	657322.FPR_26220	6.59e-52	163.0	2ED43@1|root,3370V@2|Bacteria,1VGAD@1239|Firmicutes,24RZU@186801|Clostridia,3WM6K@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00374	657322.FPR_26210	2.72e-197	546.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3WGAW@541000|Ruminococcaceae	186801|Clostridia	L	Hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
AMEPOAEB_00375	657322.FPR_26200	1.97e-230	634.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,3WIK6@541000|Ruminococcaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
AMEPOAEB_00376	657322.FPR_26190	0.0	904.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
AMEPOAEB_00377	657322.FPR_16580	5.34e-269	735.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
AMEPOAEB_00378	657322.FPR_06240	6.31e-310	844.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WGNF@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
AMEPOAEB_00379	657322.FPR_23930	0.0	997.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WRX8@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	lacZ	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
AMEPOAEB_00380	657322.FPR_10150	6.07e-248	692.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3WGSN@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,PUD
AMEPOAEB_00382	861299.J421_5958	2.35e-09	58.2	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
AMEPOAEB_00385	657322.FPR_10140	3.43e-277	764.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WH0E@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
AMEPOAEB_00386	657322.FPR_10130	3.08e-207	573.0	COG0454@1|root,COG2263@1|root,COG0456@2|Bacteria,COG2263@2|Bacteria,1UK73@1239|Firmicutes,25FNT@186801|Clostridia,3WSP2@541000|Ruminococcaceae	186801|Clostridia	JK	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,rRNA_methylase
AMEPOAEB_00387	657322.FPR_10120	0.0	1058.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,3WGUR@541000|Ruminococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
AMEPOAEB_00388	657322.FPR_10110	7.85e-241	661.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,24AVD@186801|Clostridia,3WRII@541000|Ruminococcaceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
AMEPOAEB_00389	748224.HMPREF9436_02129	1.35e-144	409.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,3WISN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
AMEPOAEB_00390	657322.FPR_10090	1.6e-187	523.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WIBR@541000|Ruminococcaceae	186801|Clostridia	C	pyridine	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
AMEPOAEB_00391	657322.FPR_10080	6.76e-246	674.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,3WJ1C@541000|Ruminococcaceae	186801|Clostridia	EJ	Asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
AMEPOAEB_00392	748224.HMPREF9436_02132	2.5e-64	197.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia,3WKWQ@541000|Ruminococcaceae	186801|Clostridia	E	branched-chain amino acid permeases (Azaleucine resistance)	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
AMEPOAEB_00393	748224.HMPREF9436_02133	2.34e-140	400.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia,3WIMT@541000|Ruminococcaceae	186801|Clostridia	E	azaleucine resistance protein AzlC	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
AMEPOAEB_00394	552398.HMPREF0866_00882	1.24e-11	67.8	COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24DU0@186801|Clostridia,3WS77@541000|Ruminococcaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
AMEPOAEB_00395	748224.HMPREF9436_01214	4.67e-65	200.0	2C2YH@1|root,31RJ6@2|Bacteria,1V7NS@1239|Firmicutes,24M7H@186801|Clostridia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
AMEPOAEB_00396	748224.HMPREF9436_01216	0.0	1130.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,PrpR_N,Sigma54_activ_2,Sigma54_activat
AMEPOAEB_00397	748224.HMPREF9436_01217	1.07e-302	828.0	COG3395@1|root,COG3395@2|Bacteria,1TPNP@1239|Firmicutes,25CF7@186801|Clostridia	186801|Clostridia	S	Putative sugar-binding N-terminal domain	-	-	2.7.1.219,2.7.1.220	ko:K22129	-	-	-	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
AMEPOAEB_00398	742741.HMPREF9475_00130	2.47e-186	528.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,21YS8@1506553|Lachnoclostridium	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
AMEPOAEB_00399	748224.HMPREF9436_01220	2.28e-213	590.0	COG0329@1|root,COG0329@2|Bacteria,1TPSG@1239|Firmicutes,249ZX@186801|Clostridia,3WNVH@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA_1	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS,DUF1357_C,DUF1537
AMEPOAEB_00400	748224.HMPREF9436_01221	1.82e-257	706.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,3WIJ8@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
AMEPOAEB_00401	748224.HMPREF9436_01222	1.24e-233	643.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WRUT@541000|Ruminococcaceae	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
AMEPOAEB_00402	748224.HMPREF9436_01223	4.78e-111	320.0	2EFUW@1|root,339M2@2|Bacteria	2|Bacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
AMEPOAEB_00403	748224.HMPREF9436_01224	3.19e-300	826.0	COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,247UH@186801|Clostridia,3WHTK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TctA
AMEPOAEB_00404	748224.HMPREF9436_01225	2.28e-230	636.0	COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,24HV2@186801|Clostridia,3WPNB@541000|Ruminococcaceae	186801|Clostridia	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
AMEPOAEB_00405	657322.FPR_24600	4.41e-236	665.0	COG2755@1|root,COG2755@2|Bacteria,1VG8J@1239|Firmicutes,24RJ2@186801|Clostridia,3WNI1@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,Lipase_GDSL_2
AMEPOAEB_00407	657322.FPR_24620	6.59e-172	480.0	COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,24HKY@186801|Clostridia,3WJVM@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
AMEPOAEB_00408	657322.FPR_24630	0.0	1221.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3WGHX@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
AMEPOAEB_00409	657322.FPR_24640	3.37e-117	336.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3WK8P@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
AMEPOAEB_00410	657322.FPR_24650	0.0	1574.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WH4M@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
AMEPOAEB_00411	657322.FPR_24660	1.72e-142	402.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3WH1B@541000|Ruminococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
AMEPOAEB_00412	657322.FPR_24670	7.18e-182	505.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,25E3F@186801|Clostridia,3WIFZ@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
AMEPOAEB_00413	748224.HMPREF9436_01053	9.63e-196	545.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3WHW9@541000|Ruminococcaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
AMEPOAEB_00414	657322.FPR_24700	7.26e-265	726.0	COG1589@1|root,COG1589@2|Bacteria,1UHVF@1239|Firmicutes,25E4A@186801|Clostridia,3WIXM@541000|Ruminococcaceae	186801|Clostridia	M	Putative stage IV sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
AMEPOAEB_00416	657322.FPR_24720	1.29e-260	715.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3WKX1@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
AMEPOAEB_00418	1235802.C823_00523	1.76e-79	247.0	COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,249V2@186801|Clostridia	186801|Clostridia	L	endonuclease exonuclease phosphatase	-	-	3.1.3.90	ko:K06896	ko00500,map00500	-	R10486	RC00017	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
AMEPOAEB_00419	657322.FPR_27940	0.0	991.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,3WJ3P@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase class C	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
AMEPOAEB_00420	657322.FPR_27950	1.09e-254	701.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia,3WHGF@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AMEPOAEB_00421	657322.FPR_27960	4.46e-235	649.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WJT0@541000|Ruminococcaceae	186801|Clostridia	M	mechanosensitive ion channel	-	-	-	ko:K16052,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3,1.A.23.4	-	-	MS_channel
AMEPOAEB_00422	657322.FPR_27970	7.5e-132	375.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3WI1Y@541000|Ruminococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
AMEPOAEB_00423	657322.FPR_27980	0.0	886.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WIF4@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00424	657322.FPR_27990	4.78e-221	610.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WGWB@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 4	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
AMEPOAEB_00425	657322.FPR_28000	4.5e-199	552.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WGHP@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
AMEPOAEB_00426	657322.FPR_28010	3.77e-131	374.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3WJ4I@541000|Ruminococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
AMEPOAEB_00427	657322.FPR_28020	7.24e-121	346.0	COG0212@1|root,COG0212@2|Bacteria	2|Bacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
AMEPOAEB_00428	657322.FPR_28030	7.25e-303	825.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3WGJK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
AMEPOAEB_00429	657322.FPR_28040	1.64e-119	341.0	COG2109@1|root,COG2109@2|Bacteria,1V70U@1239|Firmicutes,24JNB@186801|Clostridia,3WJWD@541000|Ruminococcaceae	186801|Clostridia	H	cob(I)yrinic acid a,c-diamide adenosyltransferase	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
AMEPOAEB_00430	748224.HMPREF9436_01534	2.4e-176	516.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3WGEC@541000|Ruminococcaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
AMEPOAEB_00431	657322.FPR_26410	1.94e-232	639.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3WH5D@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
AMEPOAEB_00432	657322.FPR_26400	8.04e-84	259.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,3WIIR@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
AMEPOAEB_00433	657322.FPR_30610	5.57e-316	862.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3WG8G@541000|Ruminococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
AMEPOAEB_00436	657322.FPR_30580	5.34e-64	196.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3WKMJ@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
AMEPOAEB_00437	657322.FPR_30570	9.18e-290	789.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3WGAU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
AMEPOAEB_00438	657322.FPR_30560	1.43e-249	684.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WGMR@541000|Ruminococcaceae	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
AMEPOAEB_00439	657322.FPR_30550	1.53e-266	729.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WGVU@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
AMEPOAEB_00440	657322.FPR_30540	7.01e-213	588.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3WGWA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
AMEPOAEB_00441	657322.FPR_30530	2.22e-182	507.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
AMEPOAEB_00442	657322.FPR_30520	2.38e-310	845.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3WIMU@541000|Ruminococcaceae	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
AMEPOAEB_00443	657322.FPR_30510	1.9e-99	289.0	COG0527@1|root,COG0527@2|Bacteria,1V6AQ@1239|Firmicutes,24PYP@186801|Clostridia,3WKNF@541000|Ruminococcaceae	186801|Clostridia	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_7
AMEPOAEB_00444	657322.FPR_30500	2.36e-130	370.0	COG2190@1|root,COG2190@2|Bacteria,1W092@1239|Firmicutes,25EGH@186801|Clostridia,3WSQZ@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
AMEPOAEB_00445	657322.FPR_30490	3.39e-96	290.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WHP7@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
AMEPOAEB_00447	657322.FPR_19810	3.93e-184	515.0	COG0438@1|root,COG0438@2|Bacteria,1V74B@1239|Firmicutes,2517N@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
AMEPOAEB_00448	657322.FPR_24720	1.87e-164	472.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3WKX1@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
AMEPOAEB_00449	742738.HMPREF9460_01840	3.49e-162	468.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,26A0W@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_00450	748224.HMPREF9436_00183	6.79e-105	325.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
AMEPOAEB_00451	748224.HMPREF9436_00200	1.21e-83	250.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3WM2W@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
AMEPOAEB_00452	657322.FPR_09340	4.82e-192	534.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3WGFD@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
AMEPOAEB_00453	657322.FPR_30480	0.0	991.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
AMEPOAEB_00454	657322.FPR_30470	6.8e-110	316.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
AMEPOAEB_00455	657322.FPR_30460	3.18e-202	560.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3WHYS@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
AMEPOAEB_00456	748224.HMPREF9436_01556	8.86e-176	491.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
AMEPOAEB_00457	657322.FPR_30440	0.0	1268.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3WGVF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
AMEPOAEB_00458	657322.FPR_30430	1.39e-101	295.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,3WJXW@541000|Ruminococcaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
AMEPOAEB_00459	657322.FPR_30420	1.98e-201	558.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
AMEPOAEB_00460	657322.FPR_30410	7e-36	122.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,256ZU@186801|Clostridia,3WR05@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
AMEPOAEB_00461	748224.HMPREF9436_01551	2.32e-208	585.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3WGCP@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
AMEPOAEB_00462	748224.HMPREF9436_01550	1.4e-166	469.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,3WG7R@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
AMEPOAEB_00463	657322.FPR_30380	2.75e-100	291.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3WK9U@541000|Ruminococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
AMEPOAEB_00464	657322.FPR_30370	1.29e-74	224.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3WKSG@541000|Ruminococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
AMEPOAEB_00465	657322.FPR_30360	7.67e-56	178.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
AMEPOAEB_00466	469618.FVAG_01307	2.73e-33	117.0	2EI5A@1|root,32Z4A@2|Bacteria,37CGN@32066|Fusobacteria	32066|Fusobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00467	877411.JMMA01000002_gene949	5.56e-37	131.0	COG4824@1|root,COG4824@2|Bacteria,1VDZE@1239|Firmicutes,25D0A@186801|Clostridia	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
AMEPOAEB_00468	657322.FPR_25650	4.06e-122	365.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae	186801|Clostridia	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
AMEPOAEB_00469	657322.FPR_18570	3.84e-69	211.0	COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,24N5U@186801|Clostridia,3WPZP@541000|Ruminococcaceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806	R02738,R02780,R04111,R04394,R05132,R08559	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.1,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
AMEPOAEB_00470	657322.FPR_18560	2.12e-276	755.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3WH26@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
AMEPOAEB_00471	657322.FPR_18550	2.04e-315	863.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
AMEPOAEB_00472	657322.FPR_18540	2.35e-127	361.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3WJKY@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 8.96	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
AMEPOAEB_00473	657322.FPR_18530	2.83e-65	206.0	COG3940@1|root,COG3940@2|Bacteria,1UK7X@1239|Firmicutes,25FPU@186801|Clostridia,3WMMK@541000|Ruminococcaceae	186801|Clostridia	G	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
AMEPOAEB_00474	657322.FPR_18520	3.05e-116	333.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3WJCA@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
AMEPOAEB_00475	657322.FPR_18510	7.94e-119	339.0	COG0454@1|root,COG0456@2|Bacteria,1V4Y1@1239|Firmicutes,24H0B@186801|Clostridia,3WKQG@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
AMEPOAEB_00476	657322.FPR_18500	4.77e-61	187.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24S4A@186801|Clostridia,3WQK5@541000|Ruminococcaceae	186801|Clostridia	S	Trp repressor protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
AMEPOAEB_00477	657322.FPR_18490	1.37e-117	337.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WJ0K@541000|Ruminococcaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
AMEPOAEB_00478	657322.FPR_18480	1.04e-217	600.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia,3WIHT@541000|Ruminococcaceae	186801|Clostridia	Q	FAH family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
AMEPOAEB_00479	657322.FPR_18470	1.05e-229	633.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHF9@541000|Ruminococcaceae	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
AMEPOAEB_00480	657322.FPR_18450	0.0	1211.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
AMEPOAEB_00481	657322.FPR_18440	3.52e-70	216.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,3WI50@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
AMEPOAEB_00484	657322.FPR_08970	5.26e-156	437.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24HZR@186801|Clostridia,3WJQC@541000|Ruminococcaceae	186801|Clostridia	S	phosphoglycolate phosphatase, bacterial	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
AMEPOAEB_00485	657322.FPR_08960	0.0	885.0	2DVGZ@1|root,33VUK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00487	657322.FPR_08940	1.1e-158	444.0	COG0569@1|root,COG0569@2|Bacteria,1V30C@1239|Firmicutes,24GDX@186801|Clostridia,3WJ1Y@541000|Ruminococcaceae	186801|Clostridia	C	TrkA N-terminal domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
AMEPOAEB_00488	657322.FPR_08930	1.07e-94	276.0	COG0569@1|root,COG0569@2|Bacteria,1V2ZF@1239|Firmicutes,24GNX@186801|Clostridia,3WIPU@541000|Ruminococcaceae	186801|Clostridia	C	TrkA N-terminal domain protein	trkA2	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
AMEPOAEB_00489	657322.FPR_08920	4.17e-178	498.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
AMEPOAEB_00490	657322.FPR_08910	1.42e-272	749.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3WGU0@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
AMEPOAEB_00491	657322.FPR_08900	7.05e-270	738.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3WGBS@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
AMEPOAEB_00492	657322.FPR_08890	5.08e-119	343.0	2EHNH@1|root,33BEA@2|Bacteria,1VQC1@1239|Firmicutes,24X4U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00493	657322.FPR_08880	2.22e-192	534.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,3WIEJ@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	licT	-	-	ko:K03480,ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
AMEPOAEB_00494	657322.FPR_08870	0.0	1004.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WN0C@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	glvC	-	2.7.1.199,2.7.1.208	ko:K02749,ko:K02750,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	M00266,M00268	R02738,R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.10,4.A.1.1.16,4.A.1.1.3,4.A.1.1.4,4.A.1.1.8	-	-	PTS_EIIB,PTS_EIIC
AMEPOAEB_00495	657322.FPR_08860	0.0	910.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,3WNWV@541000|Ruminococcaceae	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	3.2.1.122,3.2.1.86	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	-	R00837,R00838,R00839,R05133,R05134,R06113	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GH4,GT4	-	Glyco_hydro_4,Glyco_hydro_4C
AMEPOAEB_00496	657322.FPR_08850	2.26e-239	657.0	COG0008@1|root,COG0008@2|Bacteria,1TVW7@1239|Firmicutes,24BG2@186801|Clostridia,3WHX2@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
AMEPOAEB_00497	657322.FPR_08840	4.51e-156	437.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
AMEPOAEB_00498	657322.FPR_08830	7.35e-307	838.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WHZE@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00499	657322.FPR_08820	0.0	1070.0	COG0517@1|root,COG1227@1|root,COG4109@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
AMEPOAEB_00500	657322.FPR_29250	2.42e-266	733.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
AMEPOAEB_00501	657322.FPR_29240	1.75e-175	492.0	COG0614@1|root,COG4822@1|root,COG0614@2|Bacteria,COG4822@2|Bacteria,1UK9K@1239|Firmicutes,25FRK@186801|Clostridia,3WJHV@541000|Ruminococcaceae	186801|Clostridia	HP	small periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00502	657322.FPR_29230	1.83e-259	712.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
AMEPOAEB_00503	657322.FPR_29220	3.3e-218	605.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3WI1U@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
AMEPOAEB_00504	657322.FPR_29210	0.0	1222.0	COG1120@1|root,COG1903@1|root,COG1120@2|Bacteria,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3WH1E@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
AMEPOAEB_00505	657322.FPR_29200	6.86e-177	493.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
AMEPOAEB_00506	657322.FPR_29190	3.01e-227	627.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3WHCR@541000|Ruminococcaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
AMEPOAEB_00507	657322.FPR_29180	3.44e-84	253.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3WHE5@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-3B	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
AMEPOAEB_00508	657322.FPR_29170	4.24e-163	457.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,3WJ9U@541000|Ruminococcaceae	186801|Clostridia	H	reductase	cobK	-	1.3.1.106,1.3.1.54,1.3.1.76,4.99.1.4	ko:K02304,ko:K05895	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05150,R05812	RC01012,RC01034,RC01280	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiJ,NAD_binding_7
AMEPOAEB_00509	657322.FPR_29160	2.47e-273	749.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3WGQY@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
AMEPOAEB_00510	657322.FPR_06210	1.11e-193	536.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3WM3U@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
AMEPOAEB_00511	748224.HMPREF9436_02567	5.48e-206	576.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3WGZG@541000|Ruminococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
AMEPOAEB_00512	657322.FPR_06190	1.87e-148	419.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,24BX1@186801|Clostridia,3WPRR@541000|Ruminococcaceae	186801|Clostridia	P	amino acid ABC transporter	-	-	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
AMEPOAEB_00513	657322.FPR_06180	5.62e-183	509.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WNRV@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid ABC transporter ATP-binding protein, PAAT family	tcyN	-	-	ko:K10010,ko:K16960	ko02010,map02010	M00234,M00585	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.13,3.A.1.3.14	-	-	ABC_tran
AMEPOAEB_00514	657322.FPR_06170	3.01e-187	521.0	COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,24DHZ@186801|Clostridia,3WRQW@541000|Ruminococcaceae	186801|Clostridia	ET	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)	-	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
AMEPOAEB_00515	657322.FPR_06160	4.06e-68	206.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3WJEP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
AMEPOAEB_00516	657322.FPR_06150	2.44e-186	526.0	COG4709@1|root,COG4709@2|Bacteria,1TU53@1239|Firmicutes,24WP7@186801|Clostridia,3WKRK@541000|Ruminococcaceae	186801|Clostridia	U	Protein of unknown function (DUF1700)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
AMEPOAEB_00517	657322.FPR_06140	0.0	1214.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WH2A@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
AMEPOAEB_00518	411483.FAEPRAA2165_01222	4.88e-54	169.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3WK5I@541000|Ruminococcaceae	186801|Clostridia	G	phosphocarrier, HPr family	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
AMEPOAEB_00519	657322.FPR_06120	3e-316	859.0	COG0336@1|root,COG0454@1|root,COG0336@2|Bacteria,COG0456@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3WH8Z@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
AMEPOAEB_00520	657322.FPR_06110	4e-128	363.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WIMH@541000|Ruminococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
AMEPOAEB_00521	657322.FPR_29010	6.37e-45	160.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
AMEPOAEB_00522	657322.FPR_29000	0.0	893.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3WGBE@541000|Ruminococcaceae	186801|Clostridia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
AMEPOAEB_00523	657322.FPR_28990	1.11e-125	358.0	COG3707@1|root,COG3707@2|Bacteria,1V9FH@1239|Firmicutes,24JZU@186801|Clostridia,3WJ90@541000|Ruminococcaceae	186801|Clostridia	K	ANTAR domain protein	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
AMEPOAEB_00524	657322.FPR_28980	0.0	1097.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
AMEPOAEB_00525	657322.FPR_28970	0.0	1187.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,25FRJ@186801|Clostridia,3WKMI@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
AMEPOAEB_00528	657322.FPR_28960	1.53e-184	515.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,24GMY@186801|Clostridia,3WJXS@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
AMEPOAEB_00529	657322.FPR_28950	4.46e-192	534.0	COG0789@1|root,COG0789@2|Bacteria,1V6W4@1239|Firmicutes,24F6T@186801|Clostridia,3WKHZ@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	hmrR	-	-	-	-	-	-	-	-	-	-	-	MerR_1
AMEPOAEB_00530	657322.FPR_28940	0.0	916.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3WHAH@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
AMEPOAEB_00531	748224.HMPREF9436_01249	3.9e-99	294.0	COG0741@1|root,COG0741@2|Bacteria,1V6K4@1239|Firmicutes,24JB5@186801|Clostridia,3WKAS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
AMEPOAEB_00532	657322.FPR_28920	5.03e-133	378.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WK2C@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
AMEPOAEB_00533	657322.FPR_28910	5.76e-33	122.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
AMEPOAEB_00534	657322.FPR_28350	7.99e-183	509.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3WGHQ@541000|Ruminococcaceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
AMEPOAEB_00535	657322.FPR_28330	1.37e-140	398.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,249B1@186801|Clostridia	186801|Clostridia	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
AMEPOAEB_00536	657322.FPR_28320	0.0	912.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3WHCW@541000|Ruminococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	-	-	4.1.1.18,4.1.1.19	ko:K01582,ko:K01583,ko:K01585	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	M00133	R00462,R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
AMEPOAEB_00537	657322.FPR_28310	0.0	1010.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3WGAH@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
AMEPOAEB_00538	657322.FPR_28300	3.59e-21	83.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3WMB3@541000|Ruminococcaceae	186801|Clostridia	S	RSAM-modified six-cysteine peptide	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
AMEPOAEB_00542	748224.HMPREF9436_01606	0.0	971.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	ushA	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos,SLH
AMEPOAEB_00543	657322.FPR_28270	0.0	1220.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
AMEPOAEB_00544	657322.FPR_28260	5.26e-58	179.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3WKHY@541000|Ruminococcaceae	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
AMEPOAEB_00545	657322.FPR_28250	4.74e-210	580.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3WGKR@541000|Ruminococcaceae	186801|Clostridia	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
AMEPOAEB_00546	657322.FPR_28240	9.59e-60	197.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
AMEPOAEB_00547	657322.FPR_21150	1.89e-200	561.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WH1H@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
AMEPOAEB_00548	657322.FPR_21160	4.57e-90	264.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
AMEPOAEB_00549	657322.FPR_15770	6.64e-186	516.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
AMEPOAEB_00550	657322.FPR_15760	2.87e-270	739.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3WGZU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
AMEPOAEB_00551	657322.FPR_15750	2.85e-276	760.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
AMEPOAEB_00552	657322.FPR_15740	2.38e-223	615.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3WGNP@541000|Ruminococcaceae	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
AMEPOAEB_00554	748224.HMPREF9436_02894	1.96e-206	573.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
AMEPOAEB_00555	657322.FPR_15710	0.0	877.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
AMEPOAEB_00556	657322.FPR_15700	1.78e-209	580.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3WI8A@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AMEPOAEB_00557	657322.FPR_15690	4.65e-185	514.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3WIT8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
AMEPOAEB_00558	657322.FPR_15680	4.03e-85	251.0	COG1433@1|root,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3WK5J@541000|Ruminococcaceae	186801|Clostridia	L	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
AMEPOAEB_00559	657322.FPR_15660	7.37e-222	610.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3WN4W@541000|Ruminococcaceae	186801|Clostridia	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
AMEPOAEB_00561	657322.FPR_31090	9.95e-215	593.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3WHUA@541000|Ruminococcaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
AMEPOAEB_00562	748224.HMPREF9436_01517	7.58e-187	521.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
AMEPOAEB_00563	657322.FPR_31120	4.57e-214	591.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
AMEPOAEB_00564	657322.FPR_31130	3.35e-218	602.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3WGB3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
AMEPOAEB_00565	657322.FPR_31140	0.0	1118.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3WGTX@541000|Ruminococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
AMEPOAEB_00566	657322.FPR_31150	1.13e-154	435.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3WI7X@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
AMEPOAEB_00567	657322.FPR_31160	0.0	864.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
AMEPOAEB_00570	657322.FPR_31190	0.0	914.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	-	-	-	ko:K06295	-	-	-	-	ko00000	-	-	-	GerA
AMEPOAEB_00571	657322.FPR_31200	5.77e-149	421.0	COG2323@1|root,COG2323@2|Bacteria,1V3NW@1239|Firmicutes,24H1Q@186801|Clostridia,3WJ0A@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
AMEPOAEB_00573	657322.FPR_31220	5.25e-106	306.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
AMEPOAEB_00574	657322.FPR_31230	0.0	1440.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3WGN7@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
AMEPOAEB_00575	657322.FPR_31240	0.0	870.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae	186801|Clostridia	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
AMEPOAEB_00576	657322.FPR_31250	1.89e-316	862.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
AMEPOAEB_00577	657322.FPR_31260	3.34e-139	393.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3WGQP@541000|Ruminococcaceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
AMEPOAEB_00578	657322.FPR_31270	9.41e-296	809.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
AMEPOAEB_00579	748224.HMPREF9436_01496	4.15e-161	451.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
AMEPOAEB_00580	657322.FPR_31290	4.26e-194	547.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3WGWF@541000|Ruminococcaceae	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
AMEPOAEB_00581	657322.FPR_15580	3.71e-30	114.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,3WIHM@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
AMEPOAEB_00582	657322.FPR_15590	6.56e-74	223.0	COG3976@1|root,COG3976@2|Bacteria	2|Bacteria	S	FMN binding	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,Oxidored_FMN
AMEPOAEB_00583	657322.FPR_15600	2.75e-166	477.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
AMEPOAEB_00584	748224.HMPREF9436_01419	9.51e-46	159.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
AMEPOAEB_00585	657322.FPR_31520	1.47e-91	268.0	COG3679@1|root,COG3679@2|Bacteria,1VDFJ@1239|Firmicutes,24MY6@186801|Clostridia,3WJJP@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
AMEPOAEB_00586	657322.FPR_31510	0.0	1691.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
AMEPOAEB_00587	657322.FPR_31500	0.0	1238.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
AMEPOAEB_00588	748224.HMPREF9436_01474	4.91e-179	503.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
AMEPOAEB_00589	657322.FPR_31480	1.61e-307	839.0	COG0845@1|root,COG0845@2|Bacteria,1V9GB@1239|Firmicutes,24HX2@186801|Clostridia,3WJMC@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00590	657322.FPR_31470	3.29e-104	301.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3WJJD@541000|Ruminococcaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
AMEPOAEB_00591	657322.FPR_31460	1.7e-196	544.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
AMEPOAEB_00592	657322.FPR_31450	1.23e-135	391.0	COG3599@1|root,COG3599@2|Bacteria,1VGCY@1239|Firmicutes,24TVY@186801|Clostridia,3WM0J@541000|Ruminococcaceae	186801|Clostridia	D	DivIVA domain protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
AMEPOAEB_00593	657322.FPR_21670	6.08e-125	356.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
AMEPOAEB_00594	657322.FPR_21660	0.0	907.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
AMEPOAEB_00595	657322.FPR_21650	0.0	901.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
AMEPOAEB_00596	657322.FPR_21640	1.51e-94	276.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3WJCC@541000|Ruminococcaceae	186801|Clostridia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
AMEPOAEB_00597	657322.FPR_21630	2.11e-272	744.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3WHCZ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
AMEPOAEB_00598	657322.FPR_21620	0.0	1267.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3WH8C@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
AMEPOAEB_00599	657322.FPR_21610	0.0	1185.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
AMEPOAEB_00601	657322.FPR_24420	5.82e-39	138.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3WGBA@541000|Ruminococcaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
AMEPOAEB_00602	411483.FAEPRAA2165_02255	1.34e-20	90.1	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,3WKCH@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
AMEPOAEB_00603	657322.FPR_18140	4.14e-305	833.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3WGDY@541000|Ruminococcaceae	186801|Clostridia	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
AMEPOAEB_00604	411483.FAEPRAA2165_00347	3.09e-109	318.0	COG2246@1|root,COG2246@2|Bacteria,1TTFB@1239|Firmicutes,258CB@186801|Clostridia,3WMEE@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
AMEPOAEB_00606	657322.FPR_02150	5.68e-156	437.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
AMEPOAEB_00607	657322.FPR_02160	5.07e-282	770.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,251V9@186801|Clostridia,3WJ37@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
AMEPOAEB_00608	657322.FPR_02170	1.75e-275	753.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WGI3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
AMEPOAEB_00609	657322.FPR_02180	1.1e-276	756.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
AMEPOAEB_00610	657322.FPR_02190	0.0	1240.0	COG3509@1|root,COG3509@2|Bacteria,1V9NZ@1239|Firmicutes,24RU6@186801|Clostridia,3WPZX@541000|Ruminococcaceae	186801|Clostridia	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
AMEPOAEB_00611	657322.FPR_02200	1.02e-169	473.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3WG98@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_00613	657322.FPR_06030	1.79e-105	304.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3WJA1@541000|Ruminococcaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
AMEPOAEB_00614	657322.FPR_06020	6.86e-26	101.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
AMEPOAEB_00615	657322.FPR_17550	6.3e-251	689.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3WGEN@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
AMEPOAEB_00617	1519439.JPJG01000022_gene572	3.37e-199	568.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,2N6J5@216572|Oscillospiraceae	186801|Clostridia	P	Prismane/CO dehydrogenase family	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
AMEPOAEB_00618	657322.FPR_12930	1.11e-118	339.0	2C8MG@1|root,32X91@2|Bacteria,1VD66@1239|Firmicutes,24NA1@186801|Clostridia,3WKPS@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00619	657322.FPR_12770	5.62e-142	399.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3WIH5@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
AMEPOAEB_00620	657322.FPR_12780	5.05e-189	525.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	pyrL	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
AMEPOAEB_00621	657322.FPR_12790	5.44e-176	490.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_00622	657322.FPR_12800	0.0	1268.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WNVD@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
AMEPOAEB_00623	657322.FPR_12810	5.69e-137	386.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3WICX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00626	748224.HMPREF9436_02161	5.84e-312	850.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,MTHFR_C,RnfC_N,SLBB
AMEPOAEB_00627	657322.FPR_12850	1.26e-217	602.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3WGC0@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
AMEPOAEB_00628	657322.FPR_12860	1.54e-119	342.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3WKJX@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
AMEPOAEB_00629	657322.FPR_12870	1.44e-149	421.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3WHAI@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
AMEPOAEB_00630	657322.FPR_12880	5.63e-137	389.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3WIFG@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
AMEPOAEB_00631	941639.BCO26_0587	1.46e-35	131.0	COG0657@1|root,COG0657@2|Bacteria,1TQD4@1239|Firmicutes,4HNGN@91061|Bacilli,1ZRH2@1386|Bacillus	91061|Bacilli	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
AMEPOAEB_00632	657322.FPR_06490	4.6e-216	606.0	COG1145@1|root,COG2221@1|root,COG4624@1|root,COG1145@2|Bacteria,COG2221@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3WGZI@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
AMEPOAEB_00635	657322.FPR_21090	1.01e-184	514.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,24E6R@186801|Clostridia	186801|Clostridia	M	serine-type D-Ala-D-Ala carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
AMEPOAEB_00636	657322.FPR_21080	8.36e-277	758.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
AMEPOAEB_00637	657322.FPR_21070	3.74e-210	581.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia,3WH2P@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
AMEPOAEB_00638	657322.FPR_21060	2.31e-296	808.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGG4@541000|Ruminococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
AMEPOAEB_00639	748224.HMPREF9436_03007	7.82e-87	256.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3WK80@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
AMEPOAEB_00640	657322.FPR_21040	0.0	1612.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,3WHIF@541000|Ruminococcaceae	186801|Clostridia	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
AMEPOAEB_00642	657322.FPR_21020	0.0	910.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3WGTX@541000|Ruminococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
AMEPOAEB_00643	657322.FPR_10070	1.01e-236	672.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,3WSRG@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Response_reg
AMEPOAEB_00644	748224.HMPREF9436_02141	8.39e-115	335.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3WGMA@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
AMEPOAEB_00645	748224.HMPREF9436_02142	3.98e-120	342.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,3WJCK@541000|Ruminococcaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
AMEPOAEB_00646	657322.FPR_17720	9.8e-167	466.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WGB8@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
AMEPOAEB_00647	748224.HMPREF9436_01550	2.21e-116	339.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,3WG7R@541000|Ruminococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
AMEPOAEB_00649	657322.FPR_12490	4.16e-236	650.0	COG0392@1|root,COG0392@2|Bacteria,1V2TI@1239|Firmicutes,24K1U@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
AMEPOAEB_00650	657322.FPR_12500	0.0	1054.0	COG0438@1|root,COG0438@2|Bacteria,1V8AN@1239|Firmicutes,24IIP@186801|Clostridia	186801|Clostridia	M	Glycosyl-transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_5,Glycos_transf_1
AMEPOAEB_00652	657322.FPR_12520	1.05e-274	750.0	COG3594@1|root,COG3594@2|Bacteria,1VEEI@1239|Firmicutes,24UA2@186801|Clostridia,3WR41@541000|Ruminococcaceae	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AMEPOAEB_00653	657322.FPR_12530	0.0	980.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,24IFY@186801|Clostridia,3WRIU@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
AMEPOAEB_00654	657322.FPR_12540	7.32e-46	148.0	COG0236@1|root,COG0236@2|Bacteria,1VMEW@1239|Firmicutes,24WDM@186801|Clostridia	186801|Clostridia	IQ	Acyl carrier protein	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
AMEPOAEB_00655	657322.FPR_12550	1.11e-284	777.0	COG1020@1|root,COG1020@2|Bacteria,1VIM0@1239|Firmicutes,24UTC@186801|Clostridia,3WMHY@541000|Ruminococcaceae	186801|Clostridia	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00657	397288.C806_03275	1e-99	298.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27IXU@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.30	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00088,M00572	R01361,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
AMEPOAEB_00660	657322.FPR_16810	2.2e-51	166.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,3WJAM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
AMEPOAEB_00661	657322.FPR_16800	8.1e-100	296.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3WGC5@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
AMEPOAEB_00662	657322.FPR_04800	1.99e-218	625.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WHFT@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
AMEPOAEB_00665	657322.FPR_20010	7.76e-189	524.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3WKFF@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoribosyl transferase domain	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
AMEPOAEB_00666	657322.FPR_20000	0.0	1256.0	COG0737@1|root,COG0737@2|Bacteria,1UK63@1239|Firmicutes,25FMA@186801|Clostridia	186801|Clostridia	F	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
AMEPOAEB_00667	657322.FPR_19990	5.54e-268	736.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3WGNK@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	macB1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AMEPOAEB_00668	657322.FPR_19980	6.35e-176	490.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_00669	657322.FPR_19970	0.0	1106.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,3WHII@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
AMEPOAEB_00670	657322.FPR_19960	3.22e-94	274.0	COG5341@1|root,COG5341@2|Bacteria	2|Bacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
AMEPOAEB_00671	657322.FPR_19950	0.0	1192.0	COG1053@1|root,COG4939@1|root,COG1053@2|Bacteria,COG4939@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind
AMEPOAEB_00672	411483.FAEPRAA2165_02926	2.82e-80	246.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
AMEPOAEB_00674	657322.FPR_23760	4.49e-47	152.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24UEE@186801|Clostridia	186801|Clostridia	K	helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
AMEPOAEB_00675	1256908.HMPREF0373_02192	6.87e-129	394.0	29E39@1|root,30117@2|Bacteria,1V5FJ@1239|Firmicutes,24IZS@186801|Clostridia,25XVS@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00676	411483.FAEPRAA2165_01490	6.45e-37	132.0	COG3600@1|root,COG3600@2|Bacteria,1UW1F@1239|Firmicutes,24804@186801|Clostridia,3WJHD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF4065)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065
AMEPOAEB_00677	657322.FPR_23720	0.0	992.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
AMEPOAEB_00678	657322.FPR_23710	1.62e-58	181.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3WJT1@541000|Ruminococcaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
AMEPOAEB_00679	1123399.AQVE01000007_gene1099	5.16e-12	74.3	COG1835@1|root,COG1835@2|Bacteria,1N70C@1224|Proteobacteria,1SE0F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AMEPOAEB_00680	657322.FPR_21840	1.03e-236	650.0	COG1597@1|root,COG1597@2|Bacteria,1V1DP@1239|Firmicutes,25CN2@186801|Clostridia,3WIT5@541000|Ruminococcaceae	186801|Clostridia	I	Lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
AMEPOAEB_00681	657322.FPR_21830	0.0	1448.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WGYI@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
AMEPOAEB_00682	657322.FPR_21820	2.37e-171	481.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,25CUP@186801|Clostridia,3WJ66@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:TPM	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
AMEPOAEB_00683	657322.FPR_21810	1.34e-257	706.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00684	657322.FPR_21800	5.67e-187	531.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WHZY@541000|Ruminococcaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
AMEPOAEB_00686	646529.Desaci_3148	8.26e-14	72.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
AMEPOAEB_00687	657322.FPR_01890	2.49e-276	756.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
AMEPOAEB_00688	657322.FPR_01900	2.53e-265	726.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3WGD1@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
AMEPOAEB_00689	657322.FPR_01910	1.39e-96	281.0	COG3682@1|root,COG3682@2|Bacteria,1VQ59@1239|Firmicutes,24WQW@186801|Clostridia,3WMD3@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
AMEPOAEB_00690	657322.FPR_01920	0.0	907.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WGKI@541000|Ruminococcaceae	186801|Clostridia	C	citrate synthase	gltA2	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
AMEPOAEB_00691	657322.FPR_01930	8.46e-96	280.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00692	748224.HMPREF9436_01806	1.2e-214	599.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
AMEPOAEB_00693	657322.FPR_01950	0.0	1386.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3WGM7@541000|Ruminococcaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
AMEPOAEB_00694	657322.FPR_01960	9.52e-194	563.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3WGRB@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the FtsK SpoIIIE SftA family	spoIIIE	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
AMEPOAEB_00695	1408437.JNJN01000051_gene1022	3e-20	90.9	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25VI9@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,MTHFR_C,RnfC_N,SLBB
AMEPOAEB_00696	411471.SUBVAR_06827	2.19e-199	564.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TQF9@1239|Firmicutes,24B5Q@186801|Clostridia,3WNBB@541000|Ruminococcaceae	186801|Clostridia	G	phosphotransferase system, EIIB	-	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIB,PTS_EIIC
AMEPOAEB_00697	657322.FPR_11860	2.73e-134	381.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3WITZ@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
AMEPOAEB_00698	657322.FPR_11850	0.0	892.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3WH46@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
AMEPOAEB_00699	657322.FPR_11840	6.41e-107	309.0	COG2137@1|root,COG2137@2|Bacteria,1VM9C@1239|Firmicutes	1239|Firmicutes	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
AMEPOAEB_00700	657322.FPR_11830	5.59e-271	743.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WGST@541000|Ruminococcaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
AMEPOAEB_00701	657322.FPR_11820	5.35e-221	610.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3WGK1@541000|Ruminococcaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
AMEPOAEB_00702	657322.FPR_11810	3.27e-227	625.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3WHQ1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
AMEPOAEB_00703	657322.FPR_11800	0.0	899.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WGC1@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
AMEPOAEB_00704	657322.FPR_11790	2.31e-166	465.0	COG0745@1|root,COG0745@2|Bacteria,1TPN8@1239|Firmicutes,248UA@186801|Clostridia,3WGQR@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
AMEPOAEB_00705	657322.FPR_11780	1.61e-307	839.0	COG0457@1|root,COG0457@2|Bacteria,1VJFJ@1239|Firmicutes,25AZN@186801|Clostridia,3WS60@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00706	411483.FAEPRAA2165_02255	4.87e-159	456.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,3WKCH@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
AMEPOAEB_00707	657322.FPR_05460	4.16e-152	429.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3WIVJ@541000|Ruminococcaceae	186801|Clostridia	K	COG COG1349 Transcriptional regulators of sugar metabolism	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
AMEPOAEB_00708	189426.PODO_11865	2.22e-24	105.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,4ISQM@91061|Bacilli,26WHQ@186822|Paenibacillaceae	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
AMEPOAEB_00709	1280685.AUKC01000004_gene1649	1.62e-254	709.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,4BX6W@830|Butyrivibrio	186801|Clostridia	G	FGGY family of carbohydrate kinases, C-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
AMEPOAEB_00710	411471.SUBVAR_06752	1.22e-107	315.0	2DKYS@1|root,30XQX@2|Bacteria,1UPWU@1239|Firmicutes,25HQV@186801|Clostridia,3WNU3@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
AMEPOAEB_00711	411471.SUBVAR_06753	0.0	906.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
AMEPOAEB_00712	411471.SUBVAR_04065	0.0	1564.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,3WI73@541000|Ruminococcaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
AMEPOAEB_00713	718252.FP2_13680	0.0	1025.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3WGXZ@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
AMEPOAEB_00714	742738.HMPREF9460_00134	2.84e-92	275.0	COG0600@1|root,COG0600@2|Bacteria,1UZ7X@1239|Firmicutes,24EF4@186801|Clostridia,26B04@186813|unclassified Clostridiales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
AMEPOAEB_00715	657322.FPR_06040	2.7e-15	72.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3WGYU@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
AMEPOAEB_00716	657322.FPR_06050	1.7e-215	601.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WHF4@541000|Ruminococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00717	657322.FPR_17430	2.89e-59	192.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3WGDH@541000|Ruminococcaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
AMEPOAEB_00718	657322.FPR_17440	9.79e-199	553.0	COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,24AKZ@186801|Clostridia	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
AMEPOAEB_00719	657322.FPR_17450	7.17e-204	565.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia,3WNP8@541000|Ruminococcaceae	186801|Clostridia	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
AMEPOAEB_00720	657322.FPR_17460	0.0	913.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3WG8J@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
AMEPOAEB_00721	718252.FP2_28590	1.32e-250	687.0	COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,248R7@186801|Clostridia,3WQXH@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF871)	-	-	-	ko:K09963	-	-	-	-	ko00000	-	-	-	DUF871
AMEPOAEB_00722	657322.FPR_17480	7.52e-315	859.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00723	657322.FPR_17490	2.25e-202	559.0	COG1387@1|root,COG1387@2|Bacteria,1V2QZ@1239|Firmicutes,24GV5@186801|Clostridia,3WJ8J@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
AMEPOAEB_00724	657322.FPR_17500	9.1e-148	416.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3WJ30@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
AMEPOAEB_00725	657322.FPR_17510	1.39e-180	502.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3WGQE@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
AMEPOAEB_00726	657322.FPR_17520	9.68e-133	379.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia,3WH1N@541000|Ruminococcaceae	186801|Clostridia	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
AMEPOAEB_00727	657322.FPR_11240	3.49e-172	491.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WH1I@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
AMEPOAEB_00729	657322.FPR_11220	1.64e-239	657.0	COG4677@1|root,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,24B29@186801|Clostridia,3WJP8@541000|Ruminococcaceae	186801|Clostridia	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
AMEPOAEB_00730	748224.HMPREF9436_00247	0.0	1122.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
AMEPOAEB_00731	657322.FPR_11180	1.06e-66	201.0	29PJD@1|root,30AHI@2|Bacteria,1VC64@1239|Firmicutes,24N2Y@186801|Clostridia,3WQ27@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
AMEPOAEB_00732	657322.FPR_11170	5.13e-64	194.0	2B2ZF@1|root,32PN8@2|Bacteria,1V7B5@1239|Firmicutes,24JQY@186801|Clostridia,3WKHW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00733	657322.FPR_11160	0.0	998.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WGJQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
AMEPOAEB_00734	657322.FPR_11150	8.21e-97	282.0	2DZF8@1|root,32V97@2|Bacteria,1VK00@1239|Firmicutes,24NVD@186801|Clostridia,3WM6X@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00735	657322.FPR_11140	7.68e-39	129.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,3WKZF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
AMEPOAEB_00736	657322.FPR_11130	0.0	1145.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,2486F@186801|Clostridia,3WGI2@541000|Ruminococcaceae	186801|Clostridia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03697	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
AMEPOAEB_00737	748224.HMPREF9436_01282	2.38e-132	380.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3WJ4D@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
AMEPOAEB_00738	657322.FPR_29820	1.06e-157	442.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,3WJN0@541000|Ruminococcaceae	186801|Clostridia	S	peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
AMEPOAEB_00739	411483.FAEPRAA2165_01528	1.85e-40	133.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
AMEPOAEB_00740	657322.FPR_29810	1.08e-35	120.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3WMCT@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4250)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
AMEPOAEB_00741	657322.FPR_29800	5.07e-188	521.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,2494P@186801|Clostridia	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
AMEPOAEB_00742	657322.FPR_29790	8.96e-79	234.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
AMEPOAEB_00743	657322.FPR_29780	0.0	1584.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WGJD@541000|Ruminococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
AMEPOAEB_00744	657322.FPR_29770	3.67e-131	372.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
AMEPOAEB_00745	657322.FPR_29760	2.49e-310	847.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,3WGSM@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
AMEPOAEB_00746	657322.FPR_29750	1.76e-258	709.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24AZ4@186801|Clostridia,3WNAA@541000|Ruminococcaceae	186801|Clostridia	H	aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
AMEPOAEB_00747	1297617.JPJD01000025_gene1223	8.52e-82	248.0	28HKG@1|root,2Z7VB@2|Bacteria,1TZFI@1239|Firmicutes,24BXG@186801|Clostridia,26A99@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00748	610130.Closa_3123	7.48e-41	136.0	2DMB1@1|root,32F8N@2|Bacteria,1UK9S@1239|Firmicutes,25FRS@186801|Clostridia,2234M@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00749	742738.HMPREF9460_02239	3.54e-105	304.0	COG0835@1|root,COG0835@2|Bacteria,1V431@1239|Firmicutes,24HHD@186801|Clostridia,269N6@186813|unclassified Clostridiales	186801|Clostridia	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
AMEPOAEB_00750	742738.HMPREF9460_02240	9.78e-52	178.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,267JW@186813|unclassified Clostridiales	186801|Clostridia	NT	Histidine Phosphotransfer domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
AMEPOAEB_00751	411460.RUMTOR_01620	2.6e-137	403.0	COG2704@1|root,COG2704@2|Bacteria,1TR0A@1239|Firmicutes,24BI2@186801|Clostridia	186801|Clostridia	S	Anaerobic c4-dicarboxylate membrane transporter	-	-	-	ko:K07791,ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
AMEPOAEB_00752	657322.FPR_18070	1.34e-161	458.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
AMEPOAEB_00753	657322.FPR_18080	1.39e-72	218.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
AMEPOAEB_00755	657322.FPR_30820	4.39e-159	448.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3WIEX@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
AMEPOAEB_00756	748224.HMPREF9436_01487	5.38e-208	588.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
AMEPOAEB_00759	537013.CLOSTMETH_02361	1.16e-39	145.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,3WH95@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_00760	657322.FPR_03880	0.0	1746.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3WH0P@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
AMEPOAEB_00761	657322.FPR_03870	1.39e-83	247.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3WJVU@541000|Ruminococcaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
AMEPOAEB_00762	657322.FPR_03860	9.26e-284	778.0	COG1316@1|root,COG1316@2|Bacteria,1VBCT@1239|Firmicutes,25MDF@186801|Clostridia,3WKBP@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
AMEPOAEB_00763	657322.FPR_03840	2.55e-131	373.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3WJZX@541000|Ruminococcaceae	186801|Clostridia	H	HD superfamily hydrolase involved in NAD metabolism	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
AMEPOAEB_00764	657322.FPR_03830	1.1e-144	408.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,3WJ7X@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
AMEPOAEB_00765	657322.FPR_03820	1.79e-61	189.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3WKIM@541000|Ruminococcaceae	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
AMEPOAEB_00766	657322.FPR_03810	1.24e-150	424.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
AMEPOAEB_00767	657322.FPR_03800	4.93e-216	597.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3WGFT@541000|Ruminococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
AMEPOAEB_00768	657322.FPR_03790	1.76e-162	488.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3WH4V@541000|Ruminococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
AMEPOAEB_00769	1410612.JNKO01000018_gene3026	5.09e-38	136.0	2FFGH@1|root,347DY@2|Bacteria,1W14I@1239|Firmicutes,253SY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00770	657322.FPR_08990	1.47e-24	98.6	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WHV1@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
AMEPOAEB_00771	657322.FPR_06340	4.24e-168	473.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3WIYH@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
AMEPOAEB_00772	657322.FPR_06350	1.94e-130	370.0	COG0778@1|root,COG0778@2|Bacteria,1V3VK@1239|Firmicutes,25BI4@186801|Clostridia,3WM21@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
AMEPOAEB_00774	657322.FPR_06370	4.32e-87	258.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia,3WM0F@541000|Ruminococcaceae	186801|Clostridia	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
AMEPOAEB_00775	657322.FPR_06380	8.63e-181	504.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,3WJWQ@541000|Ruminococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE
AMEPOAEB_00776	657322.FPR_06390	9.14e-192	535.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3WIW1@541000|Ruminococcaceae	186801|Clostridia	P	NLPA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
AMEPOAEB_00777	411483.FAEPRAA2165_03034	1.41e-207	578.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3WGFP@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
AMEPOAEB_00778	657322.FPR_06410	4.1e-143	405.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3WIUE@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
AMEPOAEB_00779	657322.FPR_06420	1.96e-315	858.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WH4H@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
AMEPOAEB_00780	657322.FPR_10200	9.36e-227	624.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3WGIP@541000|Ruminococcaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
AMEPOAEB_00781	657322.FPR_10190	1.64e-204	565.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3WGJB@541000|Ruminococcaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
AMEPOAEB_00782	657322.FPR_10180	8.62e-114	327.0	298ZI@1|root,2ZW3A@2|Bacteria,1V7FU@1239|Firmicutes,24ID8@186801|Clostridia,3WJDF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF_trnsprt
AMEPOAEB_00783	411471.SUBVAR_05884	2.7e-152	431.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WH3N@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
AMEPOAEB_00784	657322.FPR_10160	0.0	1151.0	COG0583@1|root,COG2365@1|root,COG0583@2|Bacteria,COG2365@2|Bacteria,1V851@1239|Firmicutes,24P75@186801|Clostridia,3WM6J@541000|Ruminococcaceae	186801|Clostridia	K	Pfam:Y_phosphatase3C	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	HTH_1,LysR_substrate,Y_phosphatase3
AMEPOAEB_00787	657322.FPR_20990	4.85e-151	425.0	COG3764@1|root,COG3764@2|Bacteria,1VBCZ@1239|Firmicutes,24M77@186801|Clostridia,3WK15@541000|Ruminococcaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
AMEPOAEB_00788	657322.FPR_20980	4.57e-222	614.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
AMEPOAEB_00789	748224.HMPREF9436_02936	2.79e-72	222.0	COG1846@1|root,COG1846@2|Bacteria,1UQ0B@1239|Firmicutes,257MR@186801|Clostridia,3WMF0@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
AMEPOAEB_00790	657322.FPR_20960	0.0	1394.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGF7@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_00791	657322.FPR_20950	0.0	1107.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_00792	657322.FPR_20940	1.95e-220	608.0	COG0583@1|root,COG0583@2|Bacteria,1TT5B@1239|Firmicutes,24G8Z@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AMEPOAEB_00794	657322.FPR_31650	3.81e-225	619.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3WHUE@541000|Ruminococcaceae	186801|Clostridia	C	pyruvate formate lyase activating	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
AMEPOAEB_00795	657322.FPR_31640	0.0	1367.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3WGTB@541000|Ruminococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
AMEPOAEB_00796	411483.FAEPRAA2165_03439	8.1e-293	803.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WGXG@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
AMEPOAEB_00797	657322.FPR_31620	2.82e-190	528.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3WIBU@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
AMEPOAEB_00798	657322.FPR_31610	2.26e-219	607.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
AMEPOAEB_00799	657322.FPR_31600	2.97e-213	589.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	dnaD	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2,HTH_36
AMEPOAEB_00800	657322.FPR_31590	2.17e-60	186.0	2E3XF@1|root,30TZG@2|Bacteria,1US5V@1239|Firmicutes,25A4N@186801|Clostridia,3WR61@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00801	1519439.JPJG01000018_gene223	9.36e-252	696.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
AMEPOAEB_00802	657322.FPR_05070	5.32e-14	70.1	COG2746@1|root,COG2746@2|Bacteria,1TT5E@1239|Firmicutes,25CER@186801|Clostridia,3WK3S@541000|Ruminococcaceae	186801|Clostridia	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
AMEPOAEB_00803	411483.FAEPRAA2165_02572	1.68e-70	228.0	COG4677@1|root,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,24B29@186801|Clostridia,3WJP8@541000|Ruminococcaceae	186801|Clostridia	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
AMEPOAEB_00804	718252.FP2_05880	1.59e-91	279.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia,3WQ9H@541000|Ruminococcaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
AMEPOAEB_00805	718252.FP2_24180	3.56e-232	644.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,24806@186801|Clostridia,3WH3B@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
AMEPOAEB_00806	657322.FPR_02040	2.57e-243	683.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia,3WI0S@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
AMEPOAEB_00807	411471.SUBVAR_05506	1.47e-140	405.0	COG2169@1|root,COG2169@2|Bacteria,1V44Y@1239|Firmicutes,24D86@186801|Clostridia,3WS5W@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
AMEPOAEB_00808	657322.FPR_12180	2.4e-253	696.0	COG0790@1|root,COG0790@2|Bacteria,1VEK9@1239|Firmicutes	1239|Firmicutes	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
AMEPOAEB_00809	657322.FPR_12190	0.0	1138.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,24CZN@186801|Clostridia,3WMZG@541000|Ruminococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
AMEPOAEB_00810	657322.FPR_12200	1.85e-48	154.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia,3WKND@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
AMEPOAEB_00811	657322.FPR_12210	5.01e-231	637.0	2DBS1@1|root,2ZANX@2|Bacteria,1UZPQ@1239|Firmicutes,24D5T@186801|Clostridia,3WMAI@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00812	657322.FPR_12220	1.8e-76	231.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,3WISA@541000|Ruminococcaceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
AMEPOAEB_00813	657322.FPR_12230	0.0	1008.0	COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,248GG@186801|Clostridia,3WN10@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,TAT_signal
AMEPOAEB_00814	657322.FPR_12240	2.61e-196	544.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,3WIKA@541000|Ruminococcaceae	186801|Clostridia	S	Cof-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AMEPOAEB_00815	657322.FPR_02090	3.9e-149	428.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WGDB@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
AMEPOAEB_00817	657322.FPR_12950	1.61e-190	530.0	2DMNS@1|root,32SQE@2|Bacteria,1VDD5@1239|Firmicutes,24Q5C@186801|Clostridia,3WQDG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00819	657322.FPR_08490	5.63e-179	499.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WJ05@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
AMEPOAEB_00820	657322.FPR_17670	6.83e-67	212.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3WG9I@541000|Ruminococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
AMEPOAEB_00821	657322.FPR_17660	8.63e-154	432.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3WI24@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
AMEPOAEB_00825	1304872.JAGC01000009_gene297	1.19e-05	54.3	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42RKJ@68525|delta/epsilon subdivisions,2WNN5@28221|Deltaproteobacteria,2MB03@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
AMEPOAEB_00826	657322.FPR_19630	2.69e-195	542.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3WSC5@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
AMEPOAEB_00827	657322.FPR_19640	2.42e-194	538.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3WJFW@541000|Ruminococcaceae	186801|Clostridia	S	HAD hydrolase, family IIB	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AMEPOAEB_00828	657322.FPR_19650	7.81e-89	260.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WKPB@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
AMEPOAEB_00829	657322.FPR_19660	8.14e-75	224.0	2CTED@1|root,32ST9@2|Bacteria,1VD31@1239|Firmicutes,24Q04@186801|Clostridia,3WM4U@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00830	748224.HMPREF9436_01363	1.96e-64	198.0	2D04F@1|root,32T7R@2|Bacteria,1VBXI@1239|Firmicutes,24N5C@186801|Clostridia,3WK16@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
AMEPOAEB_00832	657322.FPR_12750	7.84e-133	377.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia,3WHFH@541000|Ruminococcaceae	186801|Clostridia	H	Dipicolinic acid synthetase, B subunit	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
AMEPOAEB_00833	657322.FPR_12740	1.98e-166	468.0	COG0111@1|root,COG0111@2|Bacteria,1TPUC@1239|Firmicutes,253BG@186801|Clostridia,3WJ87@541000|Ruminococcaceae	186801|Clostridia	EH	dipicolinic acid synthetase, A subunit	spoVFA	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AlaDh_PNT_C,DpaA_N
AMEPOAEB_00834	748224.HMPREF9436_01370	0.0	1236.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WST3@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SBP_bac_3,SnoaL_3
AMEPOAEB_00835	748224.HMPREF9436_01369	1.37e-130	378.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
AMEPOAEB_00836	657322.FPR_12710	0.0	1350.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
AMEPOAEB_00838	657322.FPR_12680	3.05e-95	288.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
AMEPOAEB_00839	657322.FPR_12440	4.61e-84	258.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
AMEPOAEB_00840	657322.FPR_12450	9.51e-127	372.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
AMEPOAEB_00841	742738.HMPREF9460_02277	4.58e-130	382.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,26AIE@186813|unclassified Clostridiales	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
AMEPOAEB_00842	742738.HMPREF9460_00517	3.03e-60	194.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UYSR@1239|Firmicutes,248R9@186801|Clostridia,269TQ@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
AMEPOAEB_00843	748224.HMPREF9436_02986	2.32e-180	514.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3WHA0@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
AMEPOAEB_00844	657322.FPR_30710	3.94e-106	306.0	2DN4N@1|root,32UIA@2|Bacteria,1VA2T@1239|Firmicutes,24JJM@186801|Clostridia,3WJZR@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
AMEPOAEB_00846	657322.FPR_30730	2.12e-185	516.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
AMEPOAEB_00847	657322.FPR_30740	5.81e-230	635.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia,3WJ0T@541000|Ruminococcaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
AMEPOAEB_00848	657322.FPR_30750	3.56e-51	161.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3WMI7@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
AMEPOAEB_00849	748224.HMPREF9436_01585	3.52e-209	585.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
AMEPOAEB_00850	657322.FPR_30770	1.45e-136	387.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3WJCH@541000|Ruminococcaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
AMEPOAEB_00851	657322.FPR_30780	4.73e-242	665.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3WI1B@541000|Ruminococcaceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
AMEPOAEB_00852	657322.FPR_30790	3e-157	442.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00853	748224.HMPREF9436_01589	0.0	1429.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
AMEPOAEB_00854	657322.FPR_17880	0.0	925.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WHQS@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
AMEPOAEB_00855	748224.HMPREF9436_00673	8.35e-117	344.0	2FCAY@1|root,344EI@2|Bacteria,1VZI3@1239|Firmicutes,252RF@186801|Clostridia,3WQBB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00857	657322.FPR_17840	0.0	882.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3WH5C@541000|Ruminococcaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
AMEPOAEB_00858	657322.FPR_17830	3.3e-314	857.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_00859	657322.FPR_17820	1.32e-291	795.0	COG0657@1|root,COG0657@2|Bacteria,1UEU5@1239|Firmicutes,24BRQ@186801|Clostridia	2|Bacteria	I	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
AMEPOAEB_00860	657322.FPR_17810	1.36e-207	573.0	COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,24CT5@186801|Clostridia,3WHUG@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase	rlmA	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
AMEPOAEB_00861	657322.FPR_17800	0.0	977.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,3WGP7@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
AMEPOAEB_00862	657322.FPR_17790	5.46e-309	841.0	COG4198@1|root,COG4198@2|Bacteria,1TQ52@1239|Firmicutes,24985@186801|Clostridia,3WGM6@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
AMEPOAEB_00863	657322.FPR_17780	4.93e-110	326.0	COG1306@1|root,COG1306@2|Bacteria,1UFJZ@1239|Firmicutes,24TYT@186801|Clostridia,3WJIH@541000|Ruminococcaceae	186801|Clostridia	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
AMEPOAEB_00864	657322.FPR_25610	7.73e-86	262.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHER@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
AMEPOAEB_00865	657322.FPR_25620	2.49e-12	66.2	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,3WGXM@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
AMEPOAEB_00866	657322.FPR_18260	1.24e-290	800.0	COG3757@1|root,COG3757@2|Bacteria,1V4GP@1239|Firmicutes,24FYR@186801|Clostridia,3WIS8@541000|Ruminococcaceae	186801|Clostridia	M	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Glyco_hydro_25,SH3_3
AMEPOAEB_00867	657322.FPR_18250	2.26e-135	385.0	2BB2P@1|root,324IU@2|Bacteria,1UQTN@1239|Firmicutes,257SI@186801|Clostridia,3WMSF@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4830)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4830
AMEPOAEB_00868	657322.FPR_18240	1.21e-53	168.0	COG1925@1|root,COG1925@2|Bacteria,1VYCG@1239|Firmicutes,251I2@186801|Clostridia,3WKJQ@541000|Ruminococcaceae	186801|Clostridia	G	phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
AMEPOAEB_00869	657322.FPR_18230	0.0	1054.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3WGQS@541000|Ruminococcaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
AMEPOAEB_00870	657322.FPR_18220	4.17e-114	327.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3WRU9@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
AMEPOAEB_00871	411483.FAEPRAA2165_00517	4.76e-28	108.0	COG5660@1|root,COG5660@2|Bacteria,1VKXY@1239|Firmicutes,24UK9@186801|Clostridia,3WMGN@541000|Ruminococcaceae	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
AMEPOAEB_00873	657322.FPR_18170	4.43e-308	840.0	COG0739@1|root,COG0739@2|Bacteria,1V7QV@1239|Firmicutes,24M4A@186801|Clostridia,3WNIT@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
AMEPOAEB_00874	657322.FPR_15510	3.24e-159	452.0	COG1857@1|root,COG1857@2|Bacteria,1TSM0@1239|Firmicutes,24DJI@186801|Clostridia	186801|Clostridia	L	CRISPR system CASCADE complex protein CasC	casC	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
AMEPOAEB_00875	445972.ANACOL_03247	1.36e-29	106.0	2E6BP@1|root,330ZG@2|Bacteria,1VEZW@1239|Firmicutes,24MZZ@186801|Clostridia,3WQJT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
AMEPOAEB_00876	657322.FPR_25560	2.35e-106	306.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WIXC@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
AMEPOAEB_00877	657322.FPR_25570	1.26e-112	326.0	COG1357@1|root,COG1357@2|Bacteria,1VC3K@1239|Firmicutes,24I2U@186801|Clostridia,3WKVG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide_4
AMEPOAEB_00878	657322.FPR_25580	8.49e-157	441.0	2DMDC@1|root,32PHK@2|Bacteria,1V728@1239|Firmicutes,24K2A@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5058
AMEPOAEB_00879	657322.FPR_25590	7.25e-162	455.0	28N4D@1|root,2ZB9V@2|Bacteria,1UPRR@1239|Firmicutes,24MJV@186801|Clostridia,3WQCH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00880	657322.FPR_25600	4.89e-201	556.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia,3WQ0E@541000|Ruminococcaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
AMEPOAEB_00881	657322.FPR_00400	9.81e-106	311.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_00882	657322.FPR_00390	4.44e-293	832.0	COG4591@1|root,COG4591@2|Bacteria,1UJX6@1239|Firmicutes,24A96@186801|Clostridia	186801|Clostridia	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
AMEPOAEB_00884	657322.FPR_25440	2.17e-175	490.0	COG1082@1|root,COG1082@2|Bacteria,1TRMY@1239|Firmicutes,24CP4@186801|Clostridia,3WP0G@541000|Ruminococcaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
AMEPOAEB_00885	657322.FPR_09720	3.81e-66	206.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,24G6Q@186801|Clostridia,3WJ5E@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
AMEPOAEB_00886	657322.FPR_09730	1.91e-297	812.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,3WHWQ@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
AMEPOAEB_00887	622312.ROSEINA2194_00851	0.0	1302.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
AMEPOAEB_00888	657322.FPR_09750	0.0	1548.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WHAB@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
AMEPOAEB_00889	657322.FPR_09760	4.29e-135	382.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia,3WG96@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
AMEPOAEB_00890	657322.FPR_12760	9.85e-207	578.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB_3	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	CW_binding_1,PBP5_C,Peptidase_S11
AMEPOAEB_00891	86416.Clopa_3836	4.05e-33	130.0	COG1609@1|root,COG1653@1|root,COG1609@2|Bacteria,COG1653@2|Bacteria,1V31R@1239|Firmicutes,249JU@186801|Clostridia,36H6U@31979|Clostridiaceae	186801|Clostridia	K	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_4,SBP_bac_1,SBP_bac_8
AMEPOAEB_00892	657322.FPR_21800	1.83e-124	369.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WHZY@541000|Ruminococcaceae	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
AMEPOAEB_00894	657322.FPR_08820	2.5e-70	226.0	COG0517@1|root,COG1227@1|root,COG4109@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
AMEPOAEB_00895	748224.HMPREF9436_00164	3.07e-68	209.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3WKMB@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
AMEPOAEB_00899	657322.FPR_08770	0.0	926.0	28JJB@1|root,2Z9CE@2|Bacteria,1UYKT@1239|Firmicutes,25DS9@186801|Clostridia,3WMYT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00900	657322.FPR_08760	1.63e-132	377.0	2E1BB@1|root,32AJH@2|Bacteria,1V8VB@1239|Firmicutes,24K6A@186801|Clostridia,3WPQM@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
AMEPOAEB_00902	657322.FPR_10560	1.46e-38	142.0	COG0464@1|root,COG0542@1|root,COG0464@2|Bacteria,COG0542@2|Bacteria,1TPQZ@1239|Firmicutes,24BQK@186801|Clostridia,3WGEZ@541000|Ruminococcaceae	186801|Clostridia	O	ATPase, AAA family	-	-	-	-	-	-	-	-	-	-	-	-	AAA
AMEPOAEB_00903	657322.FPR_10570	1.98e-234	644.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,3WH18@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	WYL
AMEPOAEB_00904	657322.FPR_10580	6.99e-208	574.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3WI06@541000|Ruminococcaceae	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
AMEPOAEB_00905	657322.FPR_10590	4.89e-300	819.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
AMEPOAEB_00906	657322.FPR_10600	5.77e-244	670.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae	186801|Clostridia	E	synthase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14395	DAHP_synth_1
AMEPOAEB_00907	657322.FPR_10610	1.63e-113	325.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,3WIYS@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
AMEPOAEB_00908	657322.FPR_10620	4.28e-292	798.0	COG0169@1|root,COG0703@1|root,COG0169@2|Bacteria,COG0703@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
AMEPOAEB_00909	657322.FPR_10630	1.15e-262	721.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
AMEPOAEB_00910	657322.FPR_10640	2.71e-163	461.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
AMEPOAEB_00911	657322.FPR_28710	7.64e-205	570.0	2B6VY@1|root,31ZVP@2|Bacteria,1V9UC@1239|Firmicutes,25DFR@186801|Clostridia,3WSGI@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
AMEPOAEB_00912	657322.FPR_28720	2.47e-250	687.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
AMEPOAEB_00913	657322.FPR_28730	3.93e-181	505.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3WHJ9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
AMEPOAEB_00914	657322.FPR_28740	8.57e-188	523.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,3WI77@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
AMEPOAEB_00915	657322.FPR_28750	1.06e-296	809.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WH4E@541000|Ruminococcaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
AMEPOAEB_00916	657322.FPR_28760	3.42e-178	496.0	COG3884@1|root,COG3884@2|Bacteria,1VGWN@1239|Firmicutes,24S03@186801|Clostridia,3WM1V@541000|Ruminococcaceae	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
AMEPOAEB_00917	657322.FPR_28770	6.71e-121	346.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,3WJQU@541000|Ruminococcaceae	186801|Clostridia	P	Chromate transporter	chrA1	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
AMEPOAEB_00918	657322.FPR_28780	6.2e-122	349.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,3WJQS@541000|Ruminococcaceae	186801|Clostridia	P	Chromate transporter	chrA2	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
AMEPOAEB_00919	657322.FPR_28790	4.48e-120	343.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,3WIP4@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
AMEPOAEB_00922	748224.HMPREF9436_00402	9.21e-201	560.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,24997@186801|Clostridia,3WJ9D@541000|Ruminococcaceae	186801|Clostridia	S	G5 domain	yabE	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
AMEPOAEB_00923	657322.FPR_13530	0.0	1000.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,SLH
AMEPOAEB_00924	411483.FAEPRAA2165_00757	3.29e-33	128.0	2EMH0@1|root,33F5M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
AMEPOAEB_00925	657322.FPR_13550	6.19e-244	672.0	COG5492@1|root,COG5492@2|Bacteria,1VKK8@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Laminin_G_3,SLH
AMEPOAEB_00927	657322.FPR_13570	6.19e-94	274.0	COG3108@1|root,COG3108@2|Bacteria,1VFRJ@1239|Firmicutes,24R9N@186801|Clostridia	186801|Clostridia	M	Peptidase M15A	-	-	3.4.17.14	ko:K08640	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_3
AMEPOAEB_00928	748224.HMPREF9436_00408	1.29e-31	112.0	2DRAZ@1|root,33B0U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00929	657322.FPR_13590	9.1e-39	130.0	2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,24S49@186801|Clostridia,3WQWC@541000|Ruminococcaceae	186801|Clostridia	S	SPP1 phage holin	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
AMEPOAEB_00930	657322.FPR_13600	2.06e-129	369.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3WJNY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
AMEPOAEB_00931	657322.FPR_13610	6.31e-74	231.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,249QZ@186801|Clostridia,3WNFX@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase NAD-binding domain protein	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
AMEPOAEB_00932	657322.FPR_25890	6.42e-67	211.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WIJZ@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
AMEPOAEB_00933	657322.FPR_25880	6.83e-112	334.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
AMEPOAEB_00934	657322.FPR_06680	9.83e-277	778.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
AMEPOAEB_00935	657322.FPR_06690	1.14e-74	223.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3WJJW@541000|Ruminococcaceae	186801|Clostridia	FG	Psort location Cytoplasmic, score	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
AMEPOAEB_00936	657322.FPR_06700	6.61e-123	350.0	COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,25QBJ@186801|Clostridia,3WIP6@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
AMEPOAEB_00937	657322.FPR_06710	0.0	1196.0	COG0658@1|root,COG0658@2|Bacteria,1VGSX@1239|Firmicutes,249H4@186801|Clostridia,3WKE7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence
AMEPOAEB_00938	657322.FPR_06720	2.32e-236	651.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3WJ8A@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
AMEPOAEB_00939	657322.FPR_06730	1.03e-138	392.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,3WIWX@541000|Ruminococcaceae	186801|Clostridia	L	Ribonuclease M5	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
AMEPOAEB_00940	748224.HMPREF9436_03175	9.19e-76	232.0	COG1191@1|root,COG1191@2|Bacteria,1VZE1@1239|Firmicutes,25442@186801|Clostridia,3WQK3@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
AMEPOAEB_00941	742765.HMPREF9457_03296	2.94e-92	278.0	COG2267@1|root,COG2267@2|Bacteria,1UIFD@1239|Firmicutes,25EKS@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
AMEPOAEB_00943	665956.HMPREF1032_03038	2.42e-116	338.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3WH12@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
AMEPOAEB_00944	657322.FPR_29160	1.34e-47	162.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3WGQY@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
AMEPOAEB_00945	657322.FPR_17530	1.11e-139	395.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
AMEPOAEB_00946	657322.FPR_17540	1.8e-40	137.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3WH5P@541000|Ruminococcaceae	186801|Clostridia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
AMEPOAEB_00947	748224.HMPREF9436_02243	2.44e-83	261.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3WHMP@541000|Ruminococcaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
AMEPOAEB_00948	657322.FPR_14750	0.0	910.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
AMEPOAEB_00949	657322.FPR_14740	0.0	1556.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
AMEPOAEB_00950	657322.FPR_14730	9.3e-102	295.0	2EI49@1|root,33BVM@2|Bacteria,1UKGE@1239|Firmicutes,24UMT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00951	657322.FPR_14720	2.21e-228	629.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3WH07@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
AMEPOAEB_00952	411471.SUBVAR_05613	4.12e-47	155.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
AMEPOAEB_00953	657322.FPR_14700	6.29e-72	219.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3WK11@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00954	657322.FPR_24180	5.61e-257	709.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
AMEPOAEB_00957	657322.FPR_24150	2.38e-310	845.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
AMEPOAEB_00958	657322.FPR_24140	6.02e-213	587.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia,3WIE7@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
AMEPOAEB_00959	657322.FPR_24130	0.0	889.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WGD4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
AMEPOAEB_00960	411483.FAEPRAA2165_02256	1.02e-256	712.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,24NSC@186801|Clostridia,3WIB3@541000|Ruminococcaceae	186801|Clostridia	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
AMEPOAEB_00962	657322.FPR_02840	2.01e-33	121.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,249T1@186801|Clostridia,3WMBE@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 21	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Methyltransf_23
AMEPOAEB_00963	657322.FPR_13380	3.76e-57	189.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WGVH@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
AMEPOAEB_00964	657322.FPR_13370	1.54e-87	257.0	COG0355@1|root,COG0355@2|Bacteria,1TTR8@1239|Firmicutes,24JGD@186801|Clostridia,3WJUK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
AMEPOAEB_00966	657322.FPR_13850	7.65e-187	519.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3WH40@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
AMEPOAEB_00967	657322.FPR_13840	9.33e-295	803.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WGQU@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
AMEPOAEB_00968	657322.FPR_13830	0.0	1175.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
AMEPOAEB_00969	657322.FPR_13820	4.65e-231	636.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJTI@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
AMEPOAEB_00970	657322.FPR_13810	6.03e-289	791.0	2EXX1@1|root,33R64@2|Bacteria,1VTQG@1239|Firmicutes,24Q1J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00971	657322.FPR_31370	3.71e-106	307.0	COG1994@1|root,COG1994@2|Bacteria,1VK5P@1239|Firmicutes,24UYF@186801|Clostridia	186801|Clostridia	S	Peptidase M50	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
AMEPOAEB_00972	657322.FPR_31380	9.3e-78	234.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,24RH8@186801|Clostridia,3WPUG@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
AMEPOAEB_00973	657322.FPR_31380	1.29e-84	251.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,24RH8@186801|Clostridia,3WPUG@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
AMEPOAEB_00974	657322.FPR_31370	1.16e-118	339.0	COG1994@1|root,COG1994@2|Bacteria,1VK5P@1239|Firmicutes,24UYF@186801|Clostridia	186801|Clostridia	S	Peptidase M50	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
AMEPOAEB_00975	657322.FPR_05330	1.77e-134	386.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3WI4Q@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
AMEPOAEB_00977	411469.EUBHAL_02368	2.34e-104	321.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25VI6@186806|Eubacteriaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
AMEPOAEB_00978	657322.FPR_14960	4.33e-301	832.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGE4@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_00979	657322.FPR_14950	1.49e-112	323.0	COG1846@1|root,COG1846@2|Bacteria,1VA2S@1239|Firmicutes,25CPK@186801|Clostridia,3WM6Y@541000|Ruminococcaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
AMEPOAEB_00980	657322.FPR_14940	1.17e-216	597.0	COG0152@1|root,COG0152@2|Bacteria,1VTBC@1239|Firmicutes,24ZTC@186801|Clostridia,3WH16@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
AMEPOAEB_00981	657322.FPR_14930	0.0	996.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
AMEPOAEB_00982	657322.FPR_14920	2.63e-237	654.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
AMEPOAEB_00983	657322.FPR_14910	1.45e-108	312.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3WJ8D@541000|Ruminococcaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
AMEPOAEB_00984	657322.FPR_14900	3.14e-143	412.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
AMEPOAEB_00985	748224.HMPREF9436_00913	7.07e-06	49.7	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG86@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
AMEPOAEB_00986	748224.HMPREF9436_00914	7.15e-161	460.0	2DV4W@1|root,33U20@2|Bacteria,1VUE7@1239|Firmicutes,25097@186801|Clostridia,3WP8N@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_00988	657322.FPR_21710	5.66e-231	636.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WHIU@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
AMEPOAEB_00989	657322.FPR_21720	1.4e-199	553.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,248PG@186801|Clostridia,3WRIK@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AMEPOAEB_00990	657322.FPR_21730	5.75e-103	298.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3WJQ9@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
AMEPOAEB_00991	657322.FPR_21740	0.0	1122.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WH1A@541000|Ruminococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
AMEPOAEB_00992	657322.FPR_00510	2.13e-140	395.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3WIIU@541000|Ruminococcaceae	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
AMEPOAEB_00993	657322.FPR_00500	0.0	1021.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
AMEPOAEB_00994	657322.FPR_00490	9.72e-254	695.0	COG1216@1|root,COG1216@2|Bacteria,1VV6P@1239|Firmicutes,25EH9@186801|Clostridia,3WI4V@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AMEPOAEB_00995	657322.FPR_00480	1.83e-281	772.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,3WJ8B@541000|Ruminococcaceae	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
AMEPOAEB_00996	657322.FPR_00470	6.32e-55	171.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,24MN7@186801|Clostridia,3WM3Z@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AbrB family	-	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
AMEPOAEB_00997	657322.FPR_00460	2.13e-230	633.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
AMEPOAEB_00998	657322.FPR_00450	5.07e-68	214.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3WGMA@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
AMEPOAEB_01000	657322.FPR_29080	2.51e-237	654.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
AMEPOAEB_01001	657322.FPR_29090	2.19e-221	611.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,3WGT1@541000|Ruminococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
AMEPOAEB_01002	657322.FPR_29100	8.54e-147	412.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJCY@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
AMEPOAEB_01003	657322.FPR_29110	2.23e-71	214.0	COG2087@1|root,COG2087@2|Bacteria,1UQZG@1239|Firmicutes,258SR@186801|Clostridia,3WMDV@541000|Ruminococcaceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
AMEPOAEB_01004	657322.FPR_29120	5.03e-178	496.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3WIUR@541000|Ruminococcaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
AMEPOAEB_01005	657322.FPR_29130	1.34e-110	319.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3WK4Z@541000|Ruminococcaceae	186801|Clostridia	H	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
AMEPOAEB_01006	657322.FPR_29140	1.84e-239	660.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3WGSW@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
AMEPOAEB_01007	657322.FPR_29150	2.24e-168	478.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3WH17@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
AMEPOAEB_01009	657322.FPR_02290	0.0	1013.0	COG1783@1|root,COG1783@2|Bacteria,1TT85@1239|Firmicutes,24ETQ@186801|Clostridia,3WPQU@541000|Ruminococcaceae	186801|Clostridia	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
AMEPOAEB_01010	657322.FPR_02300	0.0	1168.0	28I8J@1|root,2Z8BD@2|Bacteria,1UBQ6@1239|Firmicutes,24DZA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01011	748224.HMPREF9436_02546	2.04e-128	377.0	COG2868@1|root,COG2868@2|Bacteria	2|Bacteria	J	Cysteine protease Prp	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
AMEPOAEB_01012	657322.FPR_02330	5.29e-239	657.0	28W6R@1|root,2ZI7D@2|Bacteria,1V1MZ@1239|Firmicutes,24FAN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01015	657322.FPR_15610	4.7e-205	568.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
AMEPOAEB_01016	657322.FPR_15620	0.0	1012.0	COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia,3WH1J@541000|Ruminococcaceae	186801|Clostridia	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
AMEPOAEB_01017	657322.FPR_15630	0.0	1033.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia,3WGH9@541000|Ruminococcaceae	186801|Clostridia	C	Mannitol dehydrogenase	-	-	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
AMEPOAEB_01019	657322.FPR_05810	7.2e-166	463.0	COG3738@1|root,COG3738@2|Bacteria,1V2SQ@1239|Firmicutes,24F5T@186801|Clostridia,3WNEN@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
AMEPOAEB_01020	657322.FPR_05820	9.93e-208	574.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
AMEPOAEB_01021	657322.FPR_05830	1.07e-172	485.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WGPU@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
AMEPOAEB_01022	657322.FPR_05840	0.0	1589.0	COG2217@1|root,COG2217@2|Bacteria,1UZUH@1239|Firmicutes,24DMV@186801|Clostridia,3WGP6@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01023	748224.HMPREF9436_01850	3.41e-131	384.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3WHK6@541000|Ruminococcaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
AMEPOAEB_01024	657322.FPR_13470	3.8e-303	827.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
AMEPOAEB_01025	411483.FAEPRAA2165_00713	2.35e-47	152.0	29GWS@1|root,303UH@2|Bacteria,1TV9P@1239|Firmicutes,25A3V@186801|Clostridia,3WR4T@541000|Ruminococcaceae	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
AMEPOAEB_01026	657322.FPR_13450	2.44e-110	318.0	2E0RM@1|root,335S7@2|Bacteria,1VJ0P@1239|Firmicutes,24T08@186801|Clostridia,3WMKS@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
AMEPOAEB_01027	657322.FPR_13440	1.56e-175	489.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
AMEPOAEB_01028	657322.FPR_13430	2.72e-56	175.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WK2P@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
AMEPOAEB_01029	657322.FPR_13420	4.13e-98	287.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24IT1@186801|Clostridia,3WS1Z@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
AMEPOAEB_01030	657322.FPR_13410	1.28e-120	345.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24JWN@186801|Clostridia,3WS23@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
AMEPOAEB_01031	657322.FPR_13400	0.0	968.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
AMEPOAEB_01032	657322.FPR_26420	2.59e-170	475.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3WJ3Y@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	HHH,RadC
AMEPOAEB_01033	657322.FPR_26430	0.0	1304.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
AMEPOAEB_01034	748224.HMPREF9436_01345	0.0	1811.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WGS6@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
AMEPOAEB_01036	657322.FPR_03670	2.48e-96	280.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
AMEPOAEB_01037	657322.FPR_03660	2.21e-167	468.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,24JYN@186801|Clostridia,3WRVX@541000|Ruminococcaceae	186801|Clostridia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
AMEPOAEB_01038	657322.FPR_03650	3.5e-64	196.0	COG3906@1|root,COG3906@2|Bacteria,1VF5Z@1239|Firmicutes,24V04@186801|Clostridia,3WMSX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
AMEPOAEB_01039	657322.FPR_03640	2.08e-159	446.0	2DWX0@1|root,342AY@2|Bacteria,1UBPC@1239|Firmicutes,259A2@186801|Clostridia,3WPTT@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01040	411483.FAEPRAA2165_03172	7.8e-31	109.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia,3WKT4@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
AMEPOAEB_01041	657322.FPR_03620	1.17e-176	494.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3WH6J@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
AMEPOAEB_01042	657322.FPR_03610	7.61e-291	793.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WGAJ@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
AMEPOAEB_01043	657322.FPR_03600	2.04e-105	305.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,3WIWV@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
AMEPOAEB_01044	657322.FPR_03590	4.12e-56	174.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3WJVR@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
AMEPOAEB_01045	657322.FPR_03580	0.0	878.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
AMEPOAEB_01046	657322.FPR_03570	2.31e-141	400.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,3WJSP@541000|Ruminococcaceae	186801|Clostridia	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
AMEPOAEB_01047	657322.FPR_03560	2.79e-62	192.0	COG3409@1|root,COG3409@2|Bacteria,1VMBN@1239|Firmicutes,24V9S@186801|Clostridia	186801|Clostridia	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
AMEPOAEB_01048	657322.FPR_21480	4.04e-130	391.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WHEI@541000|Ruminococcaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
AMEPOAEB_01049	748224.HMPREF9436_00889	0.0	1238.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3WGCV@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	apu	-	2.4.1.25,3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R02112,R03122,R05196,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31,GH77	-	Alpha-amylase,Alpha-amylase_N,Glyco_hydro_77,Malt_amylase_C
AMEPOAEB_01050	657322.FPR_21460	5.69e-100	290.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3WKQY@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
AMEPOAEB_01051	657322.FPR_21450	2.22e-156	445.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
AMEPOAEB_01053	657322.FPR_21430	0.0	877.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3WHCB@541000|Ruminococcaceae	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
AMEPOAEB_01054	748224.HMPREF9436_01339	1.7e-136	404.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,3WGZ4@541000|Ruminococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
AMEPOAEB_01056	657322.FPR_06280	0.0	1102.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3WGCZ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
AMEPOAEB_01057	657322.FPR_06260	0.0	1167.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG9V@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
AMEPOAEB_01059	657322.FPR_03750	8e-227	639.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
AMEPOAEB_01060	657322.FPR_03760	0.0	911.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,3WGA0@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
AMEPOAEB_01061	657322.FPR_03770	1.85e-240	661.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3WGC6@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
AMEPOAEB_01062	657322.FPR_03780	8.34e-155	435.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3WG7D@541000|Ruminococcaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
AMEPOAEB_01064	657322.FPR_17620	5.95e-58	181.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,3WKXN@541000|Ruminococcaceae	186801|Clostridia	S	thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
AMEPOAEB_01066	657322.FPR_17600	0.0	1030.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WGRM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
AMEPOAEB_01067	657322.FPR_17590	2.16e-103	299.0	COG1846@1|root,COG1846@2|Bacteria,1V6UN@1239|Firmicutes,24JGS@186801|Clostridia,3WIVE@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
AMEPOAEB_01068	657322.FPR_17580	1.84e-86	255.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3WGSZ@541000|Ruminococcaceae	186801|Clostridia	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
AMEPOAEB_01069	657322.FPR_17570	0.0	1017.0	COG0040@1|root,COG3705@1|root,COG0040@2|Bacteria,COG3705@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3WH70@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
AMEPOAEB_01070	411483.FAEPRAA2165_02496	1.42e-70	211.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
AMEPOAEB_01071	657322.FPR_13760	6.78e-248	680.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase group 2 family protein	-	-	-	ko:K19427	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
AMEPOAEB_01072	657322.FPR_13770	0.0	895.0	2EIXX@1|root,338RG@2|Bacteria,1VJYN@1239|Firmicutes,25DS0@186801|Clostridia	186801|Clostridia	S	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
AMEPOAEB_01073	1280673.AUJJ01000012_gene1897	3.99e-94	292.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,4C0RF@830|Butyrivibrio	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
AMEPOAEB_01074	657322.FPR_13790	8.07e-262	719.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
AMEPOAEB_01075	657322.FPR_13800	0.0	872.0	COG3206@1|root,COG3206@2|Bacteria,1V867@1239|Firmicutes,24G2T@186801|Clostridia,3WRY8@541000|Ruminococcaceae	186801|Clostridia	M	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
AMEPOAEB_01076	657322.FPR_25950	0.0	976.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
AMEPOAEB_01077	657322.FPR_25940	3.31e-103	300.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
AMEPOAEB_01078	657322.FPR_25920	3.25e-107	309.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
AMEPOAEB_01079	657322.FPR_25910	7.58e-244	669.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae	186801|Clostridia	E	synthase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
AMEPOAEB_01080	657322.FPR_25900	1.56e-93	273.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24XEQ@186801|Clostridia,3WQQW@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
AMEPOAEB_01081	748224.HMPREF9436_00381	4.17e-290	805.0	COG0589@1|root,COG0589@2|Bacteria,1TPUI@1239|Firmicutes,24826@186801|Clostridia,3WHF1@541000|Ruminococcaceae	186801|Clostridia	T	Protein of unknown function (DUF1538)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
AMEPOAEB_01082	748224.HMPREF9436_00617	0.0	920.0	COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes,24C7V@186801|Clostridia,3WGB1@541000|Ruminococcaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
AMEPOAEB_01083	657322.FPR_11370	1.18e-132	375.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WJKD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
AMEPOAEB_01084	657322.FPR_11360	4.18e-209	579.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
AMEPOAEB_01085	657322.FPR_11350	6.64e-123	350.0	2C1SC@1|root,345JP@2|Bacteria,1VZK9@1239|Firmicutes,253BJ@186801|Clostridia,3WQEZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01086	748224.HMPREF9436_00613	1.29e-249	692.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,3WGB4@541000|Ruminococcaceae	186801|Clostridia	M	lipoprotein YddW precursor K01189	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
AMEPOAEB_01090	748224.HMPREF9436_01798	1.78e-166	469.0	COG2207@1|root,COG2207@2|Bacteria,1VEKW@1239|Firmicutes,24SZV@186801|Clostridia,3WM13@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
AMEPOAEB_01091	657322.FPR_01350	4.3e-294	805.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01092	657322.FPR_01340	1.19e-231	638.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	scrK	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
AMEPOAEB_01093	657322.FPR_01330	1.44e-121	347.0	COG0671@1|root,COG0671@2|Bacteria,1V7XD@1239|Firmicutes,25BF5@186801|Clostridia,3WS6D@541000|Ruminococcaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
AMEPOAEB_01094	748224.HMPREF9436_02262	1.87e-48	161.0	2ES3K@1|root,33JNI@2|Bacteria,1VKAS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01095	657322.FPR_01310	1.63e-258	709.0	COG2199@1|root,COG2199@2|Bacteria,1TSU4@1239|Firmicutes,24DMY@186801|Clostridia,3WPF4@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
AMEPOAEB_01096	657322.FPR_19750	2.25e-245	676.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3WN27@541000|Ruminococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
AMEPOAEB_01097	657322.FPR_19770	4.77e-305	833.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WH49@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01098	657322.FPR_19780	3.24e-249	684.0	COG3191@1|root,COG3191@2|Bacteria,1TQHA@1239|Firmicutes,24CV6@186801|Clostridia,3WNCI@541000|Ruminococcaceae	186801|Clostridia	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
AMEPOAEB_01099	657322.FPR_19790	0.0	868.0	COG1686@1|root,COG1686@2|Bacteria,1V97N@1239|Firmicutes,24KE3@186801|Clostridia,3WRI2@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
AMEPOAEB_01100	657322.FPR_31300	1.94e-83	246.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WMJ4@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
AMEPOAEB_01101	657322.FPR_31310	1.2e-154	434.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3WIMJ@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
AMEPOAEB_01102	657322.FPR_31320	6.04e-219	604.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3WGB7@541000|Ruminococcaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
AMEPOAEB_01103	657322.FPR_31330	5.85e-128	363.0	COG0681@1|root,COG0681@2|Bacteria,1V6R3@1239|Firmicutes,25CN6@186801|Clostridia,3WKCK@541000|Ruminococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
AMEPOAEB_01104	657322.FPR_31340	6.76e-73	219.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3WJ8U@541000|Ruminococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
AMEPOAEB_01105	411483.FAEPRAA2165_02391	2.34e-131	375.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,3WJDP@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
AMEPOAEB_01106	657322.FPR_31360	0.0	1279.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
AMEPOAEB_01107	657322.FPR_13030	5.33e-265	731.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WHD5@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
AMEPOAEB_01108	657322.FPR_13020	1.17e-220	608.0	COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,24A7U@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
AMEPOAEB_01109	657322.FPR_12990	3.45e-302	824.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
AMEPOAEB_01110	657322.FPR_12980	1.05e-101	296.0	COG4720@1|root,COG4720@2|Bacteria,1VBF6@1239|Firmicutes,25FRN@186801|Clostridia,3WSQ6@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
AMEPOAEB_01112	657322.FPR_00920	4.33e-146	412.0	COG2964@1|root,COG2964@2|Bacteria,1V2VD@1239|Firmicutes,24GH7@186801|Clostridia,3WPJI@541000|Ruminococcaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
AMEPOAEB_01113	657322.FPR_00930	2.17e-81	241.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	TdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
AMEPOAEB_01114	657322.FPR_00940	2.69e-205	575.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3WHPN@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
AMEPOAEB_01115	657322.FPR_00940	2.24e-44	154.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3WHPN@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
AMEPOAEB_01116	657322.FPR_00950	1.62e-19	87.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
AMEPOAEB_01117	657322.FPR_00950	1.08e-188	530.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
AMEPOAEB_01118	657322.FPR_00960	2.8e-277	759.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WGK3@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
AMEPOAEB_01119	657322.FPR_00970	2.46e-292	797.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3WH96@541000|Ruminococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
AMEPOAEB_01120	657322.FPR_00980	2.22e-299	815.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3WGXI@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
AMEPOAEB_01122	657322.FPR_01000	2.12e-175	489.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3WIPP@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
AMEPOAEB_01123	657322.FPR_23920	7.02e-122	348.0	COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,24JI6@186801|Clostridia,3WQFN@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AMEPOAEB_01124	1408323.JQKK01000014_gene48	3.06e-16	77.8	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,27ISP@186928|unclassified Lachnospiraceae	186801|Clostridia	V	HsdM N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HsdM_N,N6_Mtase
AMEPOAEB_01125	748224.HMPREF9436_00140	0.0	1321.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
AMEPOAEB_01126	657322.FPR_23880	3.16e-46	149.0	COG1314@1|root,COG1314@2|Bacteria,1VP2Z@1239|Firmicutes,24UWV@186801|Clostridia	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
AMEPOAEB_01127	657322.FPR_23870	0.0	979.0	COG0768@1|root,COG0768@2|Bacteria,1TQKI@1239|Firmicutes,25CAC@186801|Clostridia,3WI5D@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
AMEPOAEB_01128	657322.FPR_05480	2.02e-216	601.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
AMEPOAEB_01129	657322.FPR_05470	0.0	987.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia,3WNUW@541000|Ruminococcaceae	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
AMEPOAEB_01130	657322.FPR_05460	7.63e-169	473.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3WIVJ@541000|Ruminococcaceae	186801|Clostridia	K	COG COG1349 Transcriptional regulators of sugar metabolism	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
AMEPOAEB_01131	657322.FPR_05450	4.87e-206	571.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3WH8H@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
AMEPOAEB_01132	657322.FPR_05440	1.28e-237	667.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3WHCI@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
AMEPOAEB_01133	657322.FPR_05440	2e-142	419.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3WHCI@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
AMEPOAEB_01134	411483.FAEPRAA2165_02438	8.73e-31	116.0	COG0395@1|root,COG0395@2|Bacteria,1TPDZ@1239|Firmicutes,248N3@186801|Clostridia,3WI6D@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AMEPOAEB_01135	657322.FPR_16180	9.52e-131	377.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,3WGIU@541000|Ruminococcaceae	186801|Clostridia	EM	Belongs to the DapA family	nanA	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
AMEPOAEB_01136	657322.FPR_16180	6.28e-53	174.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,3WGIU@541000|Ruminococcaceae	186801|Clostridia	EM	Belongs to the DapA family	nanA	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
AMEPOAEB_01137	657322.FPR_16190	2.97e-109	313.0	COG2731@1|root,COG2731@2|Bacteria,1VCI9@1239|Firmicutes,24QNC@186801|Clostridia,3WM8D@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
AMEPOAEB_01138	657322.FPR_16200	2.58e-163	457.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3WJ12@541000|Ruminococcaceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
AMEPOAEB_01139	657322.FPR_16210	8.1e-209	578.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHCD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
AMEPOAEB_01140	657322.FPR_16220	6.97e-157	439.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3WJHA@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AMEPOAEB_01143	657322.FPR_12120	0.0	1495.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
AMEPOAEB_01144	657322.FPR_12110	1.79e-209	578.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,3WJ88@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
AMEPOAEB_01145	657322.FPR_12100	2.09e-54	170.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia,3WKXC@541000|Ruminococcaceae	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
AMEPOAEB_01146	657322.FPR_12090	3.59e-150	424.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3WI9G@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
AMEPOAEB_01147	748224.HMPREF9436_01715	1.43e-44	147.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3WK33@541000|Ruminococcaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
AMEPOAEB_01148	657322.FPR_12060	1.49e-97	283.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3WJN5@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
AMEPOAEB_01149	657322.FPR_11980	7.6e-118	337.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3WJHQ@541000|Ruminococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
AMEPOAEB_01150	657322.FPR_11970	1.14e-83	247.0	COG1266@1|root,COG1266@2|Bacteria,1VKW2@1239|Firmicutes,24QJG@186801|Clostridia,3WM89@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
AMEPOAEB_01151	657322.FPR_11960	7.2e-200	554.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,3WRI5@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
AMEPOAEB_01152	657322.FPR_11950	7.94e-174	486.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,3WJEH@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
AMEPOAEB_01153	657322.FPR_11940	1.36e-242	665.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,3WJ0Z@541000|Ruminococcaceae	186801|Clostridia	E	Renal dipeptidase family protein	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
AMEPOAEB_01154	657322.FPR_11930	0.0	1201.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae	186801|Clostridia	KL	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
AMEPOAEB_01155	657322.FPR_11930	1.44e-259	743.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae	186801|Clostridia	KL	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
AMEPOAEB_01157	657322.FPR_20890	0.0	956.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3WHJ3@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type oligopeptide transport system periplasmic component	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
AMEPOAEB_01158	657322.FPR_20880	2.35e-244	670.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
AMEPOAEB_01159	657322.FPR_20870	8.82e-241	661.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
AMEPOAEB_01160	657322.FPR_20860	2.07e-238	657.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WITY@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
AMEPOAEB_01161	657322.FPR_20850	8.55e-23	94.4	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WIHH@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
AMEPOAEB_01163	657322.FPR_10530	7.64e-199	562.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3WGTH@541000|Ruminococcaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
AMEPOAEB_01164	657322.FPR_10540	1.03e-237	652.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3WGKW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
AMEPOAEB_01165	657322.FPR_10550	8.09e-53	171.0	2CHRH@1|root,2ZES1@2|Bacteria,1W4VA@1239|Firmicutes,257KM@186801|Clostridia,3WRBD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01168	748224.HMPREF9436_00598	0.0	977.0	2EJ3B@1|root,33CUJ@2|Bacteria,1VZS4@1239|Firmicutes,253ZC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01169	657322.FPR_07730	0.0	966.0	2EJ3B@1|root,33CUJ@2|Bacteria,1VZS4@1239|Firmicutes,253ZC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01173	748224.HMPREF9436_00591	0.0	884.0	COG1653@1|root,COG1653@2|Bacteria,1TRST@1239|Firmicutes,24APZ@186801|Clostridia	186801|Clostridia	G	COG COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
AMEPOAEB_01174	748224.HMPREF9436_00590	0.0	963.0	COG2197@1|root,COG2197@2|Bacteria,1UYM1@1239|Firmicutes,2497D@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
AMEPOAEB_01175	411483.FAEPRAA2165_02269	6.24e-33	125.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
AMEPOAEB_01176	657322.FPR_20580	8.23e-215	592.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3WGDX@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
AMEPOAEB_01177	657322.FPR_20570	0.0	960.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3WGP2@541000|Ruminococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
AMEPOAEB_01178	657322.FPR_20560	2.41e-166	466.0	COG3279@1|root,COG3279@2|Bacteria,1VEBW@1239|Firmicutes,24NE6@186801|Clostridia,3WM2U@541000|Ruminococcaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
AMEPOAEB_01179	657322.FPR_20540	5.56e-208	582.0	COG3290@1|root,COG3290@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3WIB6@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
AMEPOAEB_01181	657322.FPR_20520	3.26e-106	306.0	COG2731@1|root,COG2731@2|Bacteria,1VFU3@1239|Firmicutes,24JDR@186801|Clostridia,3WQG1@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
AMEPOAEB_01182	657322.FPR_20510	2.32e-110	336.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WHCF@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
AMEPOAEB_01183	748224.HMPREF9436_01646	9.19e-310	880.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3WGNX@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
AMEPOAEB_01184	657322.FPR_02220	3.5e-307	840.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WGX2@541000|Ruminococcaceae	186801|Clostridia	S	xanthine uracil permease family protein K06901	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
AMEPOAEB_01185	657322.FPR_02230	0.0	1426.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
AMEPOAEB_01186	411483.FAEPRAA2165_00771	0.0	974.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae	186801|Clostridia	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
AMEPOAEB_01187	657322.FPR_29300	3.52e-311	847.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
AMEPOAEB_01188	657322.FPR_29310	1.78e-244	674.0	COG2433@1|root,COG2433@2|Bacteria,1UK5K@1239|Firmicutes,25FKU@186801|Clostridia,3WSNW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
AMEPOAEB_01189	657322.FPR_29320	3.86e-75	244.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3WGY6@541000|Ruminococcaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
AMEPOAEB_01190	657322.FPR_02840	1.09e-175	490.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,249T1@186801|Clostridia,3WMBE@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 21	-	-	-	ko:K07011,ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Methyltransf_23
AMEPOAEB_01191	657322.FPR_02850	6.52e-217	598.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3WGQ3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
AMEPOAEB_01192	657322.FPR_02860	8.39e-234	641.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3WGZV@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
AMEPOAEB_01194	748224.HMPREF9436_02509	4.39e-272	742.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02615	GDP_Man_Dehyd
AMEPOAEB_01195	657322.FPR_02890	2.08e-138	391.0	COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,24FY8@186801|Clostridia,3WK6K@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PRK
AMEPOAEB_01196	657322.FPR_05380	4.48e-145	409.0	COG0437@1|root,COG0437@2|Bacteria,1TT1R@1239|Firmicutes,24FGW@186801|Clostridia,3WMM7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
AMEPOAEB_01198	657322.FPR_05400	1.23e-181	505.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,3WPB6@541000|Ruminococcaceae	186801|Clostridia	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
AMEPOAEB_01199	657322.FPR_05410	0.0	1130.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3WGIC@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
AMEPOAEB_01200	657322.FPR_05420	4.86e-132	385.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
AMEPOAEB_01202	657322.FPR_15930	4.16e-159	446.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3WHG7@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	cpsE	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
AMEPOAEB_01203	657322.FPR_15920	0.0	1083.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WG9S@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
AMEPOAEB_01204	657322.FPR_15910	7.59e-245	672.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3WGY4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
AMEPOAEB_01205	657322.FPR_15900	3.63e-124	354.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3WJ0F@541000|Ruminococcaceae	186801|Clostridia	E	Acetolactate synthase small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
AMEPOAEB_01206	657322.FPR_15890	7.46e-297	815.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
AMEPOAEB_01207	657322.FPR_10410	0.0	1196.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
AMEPOAEB_01208	657322.FPR_10420	3.81e-171	478.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3WKKW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
AMEPOAEB_01209	657322.FPR_10430	1.63e-146	412.0	COG0454@1|root,COG0456@2|Bacteria,1VGV3@1239|Firmicutes,24RSS@186801|Clostridia,3WKI5@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
AMEPOAEB_01210	657322.FPR_10440	1.92e-209	580.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3WGGT@541000|Ruminococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
AMEPOAEB_01211	657322.FPR_10450	7.17e-164	459.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
AMEPOAEB_01212	657322.FPR_10460	0.0	1079.0	COG1080@1|root,COG1080@2|Bacteria,1VRWJ@1239|Firmicutes,24ZIS@186801|Clostridia,3WMYU@541000|Ruminococcaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
AMEPOAEB_01213	657322.FPR_10470	1.44e-274	752.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,3WJ3G@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
AMEPOAEB_01214	657322.FPR_10480	2.42e-159	446.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3WS73@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
AMEPOAEB_01215	657322.FPR_10490	7.54e-241	662.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24AI7@186801|Clostridia,3WMXA@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AMEPOAEB_01216	748224.HMPREF9436_02120	7.77e-99	293.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	rcoM2	GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02477,ko:K21696	-	-	-	-	ko00000,ko02022,ko03000	-	-	-	EAL,LytTR,Response_reg
AMEPOAEB_01217	657322.FPR_14810	0.0	953.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WHE3@541000|Ruminococcaceae	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
AMEPOAEB_01218	657322.FPR_14820	3.48e-44	143.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
AMEPOAEB_01219	657322.FPR_14830	9.52e-205	566.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3WGZ8@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
AMEPOAEB_01220	657322.FPR_14840	5.43e-228	628.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,25E47@186801|Clostridia,3WSKG@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
AMEPOAEB_01221	657322.FPR_14850	1.85e-213	591.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,3WHBA@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
AMEPOAEB_01222	657322.FPR_14860	8.46e-212	586.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,3WGKK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
AMEPOAEB_01223	657322.FPR_30310	8.91e-07	52.4	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
AMEPOAEB_01225	657322.FPR_07270	1.16e-84	259.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
AMEPOAEB_01226	457421.CBFG_02491	1.61e-74	234.0	COG1737@1|root,COG1737@2|Bacteria,1TR75@1239|Firmicutes,249DG@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
AMEPOAEB_01227	931276.Cspa_c50630	2.15e-241	679.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,36DV0@31979|Clostridiaceae	186801|Clostridia	G	PTS system, glucose-like IIB	-	-	2.7.1.208	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	M00268	R04111	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.10,4.A.1.1.16,4.A.1.1.4,4.A.1.1.8	-	-	PTS_EIIB,PTS_EIIC
AMEPOAEB_01228	290402.Cbei_4805	5.38e-258	714.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,36E8R@31979|Clostridiaceae	186801|Clostridia	G	Family 4 glycosyl hydrolase C-terminal domain	-	-	3.2.1.122,3.2.1.86	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	-	R00837,R00838,R00839,R05133,R05134,R06113	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GH4,GT4	-	Glyco_hydro_4,Glyco_hydro_4C
AMEPOAEB_01229	657322.FPR_24890	1.17e-58	190.0	2EIAU@1|root,33C28@2|Bacteria,1VM81@1239|Firmicutes,2527Y@186801|Clostridia,3WKZU@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated (Cas) DxTHG family	-	-	-	-	-	-	-	-	-	-	-	-	Cas_DxTHG
AMEPOAEB_01231	657322.FPR_24910	1.28e-151	447.0	COG1517@1|root,COG1517@2|Bacteria,1UYKN@1239|Firmicutes,249ZK@186801|Clostridia,3WKZT@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated (Cas) DxTHG family	-	-	-	-	-	-	-	-	-	-	-	-	Cas_DxTHG
AMEPOAEB_01232	1408311.JNJM01000013_gene2306	6.18e-120	382.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,2PTAR@265975|Oribacterium	186801|Clostridia	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,DEAD,DUF559,Helicase_C,UvrD_C
AMEPOAEB_01234	657322.FPR_09890	1.06e-258	708.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
AMEPOAEB_01235	657322.FPR_09880	2.48e-177	494.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,3WHWH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
AMEPOAEB_01236	657322.FPR_09870	3.41e-190	528.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,3WHXZ@541000|Ruminococcaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
AMEPOAEB_01237	657322.FPR_09860	2.16e-83	245.0	COG1917@1|root,COG1917@2|Bacteria,1V7FN@1239|Firmicutes	1239|Firmicutes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
AMEPOAEB_01238	657322.FPR_09850	5.72e-151	424.0	COG0698@1|root,COG0698@2|Bacteria,1TQQJ@1239|Firmicutes,249IB@186801|Clostridia,3WJSF@541000|Ruminococcaceae	186801|Clostridia	G	Ribose Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3666,LacAB_rpiB
AMEPOAEB_01239	657322.FPR_09840	6.16e-90	264.0	COG4828@1|root,COG4828@2|Bacteria,1VACG@1239|Firmicutes,24NXE@186801|Clostridia,3WR10@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
AMEPOAEB_01241	748224.HMPREF9436_02483	1.57e-107	312.0	COG1309@1|root,COG1309@2|Bacteria,1V7J5@1239|Firmicutes,24JZZ@186801|Clostridia,3WKDX@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AMEPOAEB_01242	657322.FPR_03030	1.15e-115	332.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3WJC2@541000|Ruminococcaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
AMEPOAEB_01243	657322.FPR_03020	4.88e-291	795.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3WGMX@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
AMEPOAEB_01248	657322.FPR_18630	1.24e-164	460.0	COG1396@1|root,COG1396@2|Bacteria,1V2ZX@1239|Firmicutes,24EC9@186801|Clostridia,3WIEA@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
AMEPOAEB_01249	657322.FPR_18620	2.43e-67	211.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,zinc_ribbon_2
AMEPOAEB_01250	657322.FPR_18610	8.42e-164	457.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3WJQD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
AMEPOAEB_01252	657322.FPR_18590	3.47e-246	677.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24E1V@186801|Clostridia,3WPUU@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
AMEPOAEB_01253	657322.FPR_18580	1.75e-275	756.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,3WJFN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
AMEPOAEB_01254	657322.FPR_20720	7.44e-317	874.0	COG1316@1|root,COG4223@1|root,COG1316@2|Bacteria,COG4223@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,3WJ6Y@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_PPF,LytR_cpsA_psr,NMT1
AMEPOAEB_01255	657322.FPR_20710	6.14e-71	214.0	COG5341@1|root,COG5341@2|Bacteria,1VII9@1239|Firmicutes,24SGZ@186801|Clostridia,3WQHY@541000|Ruminococcaceae	186801|Clostridia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
AMEPOAEB_01256	657322.FPR_20700	0.0	1253.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
AMEPOAEB_01258	657322.FPR_16740	8.24e-144	406.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3WHD9@541000|Ruminococcaceae	186801|Clostridia	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
AMEPOAEB_01259	657322.FPR_16730	0.0	1573.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WIEK@541000|Ruminococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,PAS_3,Response_reg
AMEPOAEB_01261	657322.FPR_16710	3.23e-254	700.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
AMEPOAEB_01262	657322.FPR_30270	3.3e-253	701.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHVR@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
AMEPOAEB_01263	748224.HMPREF9436_01538	0.0	1159.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
AMEPOAEB_01264	748224.HMPREF9436_01539	2.4e-113	336.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
AMEPOAEB_01266	657322.FPR_30310	1.78e-30	108.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
AMEPOAEB_01268	657322.FPR_30330	1.92e-240	662.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3WJA7@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AE (spore_III_AE)	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
AMEPOAEB_01270	748224.HMPREF9436_01545	7.24e-62	196.0	2E6BB@1|root,32FH3@2|Bacteria,1V7J4@1239|Firmicutes,24J8Z@186801|Clostridia,3WKIY@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
AMEPOAEB_01271	657322.FPR_30360	7.49e-120	345.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
AMEPOAEB_01272	657322.FPR_27860	1.54e-146	425.0	COG5492@1|root,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3WPAR@541000|Ruminococcaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
AMEPOAEB_01273	657322.FPR_27850	0.0	1177.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
AMEPOAEB_01274	657322.FPR_27840	1.17e-119	343.0	2B6MH@1|root,31ZJY@2|Bacteria,1VA4Q@1239|Firmicutes,24T66@186801|Clostridia,3WRG6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01275	657322.FPR_27830	6.17e-203	562.0	28PVZ@1|root,2ZCGE@2|Bacteria,1UPNZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01276	657322.FPR_27820	3.96e-127	370.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3WGN5@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
AMEPOAEB_01277	657322.FPR_16470	2.04e-115	330.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24QK7@186801|Clostridia,3WJUF@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
AMEPOAEB_01278	657322.FPR_16460	0.0	1075.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WHGT@541000|Ruminococcaceae	186801|Clostridia	E	asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7,NAD_synthase
AMEPOAEB_01279	657322.FPR_16450	0.0	1299.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae	186801|Clostridia	J	translation elongation	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
AMEPOAEB_01280	657322.FPR_06500	9.64e-317	862.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
AMEPOAEB_01282	657322.FPR_06510	3.33e-284	778.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
AMEPOAEB_01283	657322.FPR_06520	0.0	884.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
AMEPOAEB_01284	657322.FPR_15030	0.0	1051.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WGVW@541000|Ruminococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
AMEPOAEB_01285	657322.FPR_15020	5.45e-241	665.0	2DPZM@1|root,33447@2|Bacteria,1VKXN@1239|Firmicutes,25FPN@186801|Clostridia,3WMCE@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01286	657322.FPR_15010	0.0	1133.0	COG0491@1|root,COG4099@1|root,COG0491@2|Bacteria,COG4099@2|Bacteria,1TRER@1239|Firmicutes,2492V@186801|Clostridia,3WMT7@541000|Ruminococcaceae	186801|Clostridia	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,BAAT_C,Peptidase_S9
AMEPOAEB_01287	657322.FPR_14990	7.96e-28	110.0	COG3250@1|root,COG3250@2|Bacteria,1TQAM@1239|Firmicutes,248XS@186801|Clostridia,3WI0J@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
AMEPOAEB_01288	657322.FPR_28100	5.52e-305	845.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
AMEPOAEB_01289	657322.FPR_28110	4.97e-70	211.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3WJW1@541000|Ruminococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
AMEPOAEB_01290	657322.FPR_28120	5.97e-138	390.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WHNZ@541000|Ruminococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
AMEPOAEB_01291	657322.FPR_28130	2.48e-111	320.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
AMEPOAEB_01293	657322.FPR_28140	3.83e-127	361.0	COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,24IDK@186801|Clostridia,3WIF9@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
AMEPOAEB_01295	657322.FPR_18310	9.36e-295	804.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
AMEPOAEB_01296	657322.FPR_18300	3.36e-219	605.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3WGZJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
AMEPOAEB_01297	657322.FPR_18290	0.0	917.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3WGBU@541000|Ruminococcaceae	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
AMEPOAEB_01298	657322.FPR_18280	2.46e-295	805.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3WGG9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
AMEPOAEB_01300	657322.FPR_10730	7.83e-149	421.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia,3WJCX@541000|Ruminococcaceae	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
AMEPOAEB_01301	748224.HMPREF9436_01990	1.07e-288	795.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WHF6@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01302	657322.FPR_10710	7.85e-139	392.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WJ2R@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
AMEPOAEB_01303	657322.FPR_10700	1.32e-261	720.0	COG3271@1|root,COG3271@2|Bacteria,1V1IQ@1239|Firmicutes,24FBU@186801|Clostridia,3WNEZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
AMEPOAEB_01305	657322.FPR_21550	1.88e-112	324.0	2EJZS@1|root,33DQA@2|Bacteria,1VHWG@1239|Firmicutes,24STU@186801|Clostridia,3WMHW@541000|Ruminococcaceae	186801|Clostridia	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
AMEPOAEB_01306	748224.HMPREF9436_00897	6.98e-163	461.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
AMEPOAEB_01307	657322.FPR_21530	1.63e-235	649.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3WGF8@541000|Ruminococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
AMEPOAEB_01308	657322.FPR_21520	1.49e-131	373.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
AMEPOAEB_01309	657322.FPR_21510	2.64e-87	257.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,3WK0P@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
AMEPOAEB_01310	657322.FPR_17970	2e-101	303.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3WH82@541000|Ruminococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
AMEPOAEB_01313	657322.FPR_18020	8.13e-284	775.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
AMEPOAEB_01314	748224.HMPREF9436_02030	0.0	899.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
AMEPOAEB_01315	657322.FPR_18040	2.1e-85	256.0	2C9HT@1|root,2ZDJ9@2|Bacteria,1W4SA@1239|Firmicutes,255IW@186801|Clostridia,3WQUU@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
AMEPOAEB_01316	657322.FPR_16700	4.84e-312	851.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WNCZ@541000|Ruminococcaceae	186801|Clostridia	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
AMEPOAEB_01317	748224.HMPREF9436_02394	1.98e-232	644.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
AMEPOAEB_01318	657322.FPR_16680	0.0	1224.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
AMEPOAEB_01319	657322.FPR_11100	1.01e-179	500.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3WIKF@541000|Ruminococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
AMEPOAEB_01320	657322.FPR_11090	4.1e-183	510.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3WGYM@541000|Ruminococcaceae	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
AMEPOAEB_01321	657322.FPR_11080	1.87e-216	597.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG8V@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	cbiO	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
AMEPOAEB_01322	657322.FPR_11070	1.02e-196	545.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3WG9K@541000|Ruminococcaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
AMEPOAEB_01323	657322.FPR_11060	4.04e-142	404.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
AMEPOAEB_01324	657322.FPR_21780	6.39e-129	377.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WGU8@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
AMEPOAEB_01325	657322.FPR_21780	8.97e-182	515.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WGU8@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
AMEPOAEB_01326	657322.FPR_21770	0.0	876.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3WGP4@541000|Ruminococcaceae	186801|Clostridia	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
AMEPOAEB_01327	657322.FPR_21760	3.95e-309	843.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia,3WGW3@541000|Ruminococcaceae	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
AMEPOAEB_01328	657322.FPR_21750	6.34e-253	695.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3WI1M@541000|Ruminococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
AMEPOAEB_01329	657322.FPR_30100	9.36e-269	741.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
AMEPOAEB_01330	748224.HMPREF9436_01003	2e-209	607.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,25E4R@186801|Clostridia,3WS66@541000|Ruminococcaceae	186801|Clostridia	C	Membrane domain of glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
AMEPOAEB_01331	657322.FPR_30080	1.38e-206	572.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
AMEPOAEB_01332	657322.FPR_20300	0.0	979.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3WHAG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
AMEPOAEB_01333	657322.FPR_20310	6.35e-46	148.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3WKU1@541000|Ruminococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
AMEPOAEB_01334	657322.FPR_20320	3.21e-209	577.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3WGGA@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
AMEPOAEB_01335	657322.FPR_20330	4.63e-297	809.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3WGFU@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
AMEPOAEB_01336	657322.FPR_09380	0.0	2333.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,3WGTT@541000|Ruminococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
AMEPOAEB_01337	657322.FPR_08660	7.31e-211	590.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WNWQ@541000|Ruminococcaceae	186801|Clostridia	V	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01338	657322.FPR_08670	0.0	1228.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UVGW@1239|Firmicutes,24BFU@186801|Clostridia	186801|Clostridia	C	FMN_bind	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind
AMEPOAEB_01339	657322.FPR_08680	7.55e-212	586.0	COG0583@1|root,COG0583@2|Bacteria,1V09D@1239|Firmicutes,24H18@186801|Clostridia,3WJMG@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AMEPOAEB_01340	657322.FPR_08690	2.81e-121	353.0	28JHK@1|root,2Z9B4@2|Bacteria,1TS7Y@1239|Firmicutes,249S0@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01341	545696.HOLDEFILI_03331	1.12e-216	605.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,3VNWF@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
AMEPOAEB_01342	657322.FPR_11250	3.29e-163	456.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3WGIQ@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	resD	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
AMEPOAEB_01343	657322.FPR_11260	0.0	882.0	COG0110@1|root,COG3774@1|root,COG0110@2|Bacteria,COG3774@2|Bacteria,1VHA7@1239|Firmicutes,24T1B@186801|Clostridia,3WQZT@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
AMEPOAEB_01344	657322.FPR_11270	3.32e-300	820.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL,WD40
AMEPOAEB_01345	657322.FPR_11280	1.18e-27	105.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,24HEU@186801|Clostridia,3WJ3B@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0340 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF436
AMEPOAEB_01346	657322.FPR_11280	8.99e-87	257.0	COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,24HEU@186801|Clostridia,3WJ3B@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0340 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF436
AMEPOAEB_01347	657322.FPR_11290	4.25e-160	449.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WGKD@541000|Ruminococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
AMEPOAEB_01349	718252.FP2_28640	0.0	959.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3WH2V@541000|Ruminococcaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
AMEPOAEB_01350	411483.FAEPRAA2165_01186	0.0	956.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
AMEPOAEB_01351	718252.FP2_28620	4.93e-270	746.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5,RHS_repeat
AMEPOAEB_01352	657322.FPR_21180	5.6e-105	316.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3WGN3@541000|Ruminococcaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
AMEPOAEB_01353	657322.FPR_21190	1.01e-170	477.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3WHDN@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
AMEPOAEB_01354	657322.FPR_21200	4.33e-57	177.0	COG4115@1|root,COG4115@2|Bacteria,1VAM5@1239|Firmicutes,24N6K@186801|Clostridia	186801|Clostridia	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	YoeB_toxin
AMEPOAEB_01355	657322.FPR_21210	3.28e-52	164.0	COG2161@1|root,COG2161@2|Bacteria,1VCZ4@1239|Firmicutes,24PB9@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
AMEPOAEB_01356	657322.FPR_21220	0.0	890.0	COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,249NA@186801|Clostridia,3WNIF@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the serine threonine dehydratase family. DsdA subfamily	dsdA	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	PALP
AMEPOAEB_01358	657322.FPR_30160	1.04e-129	369.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
AMEPOAEB_01359	657322.FPR_30150	5.98e-55	172.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
AMEPOAEB_01360	657322.FPR_30140	7.15e-199	552.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
AMEPOAEB_01361	657322.FPR_30130	1.66e-73	220.0	29NZE@1|root,309XJ@2|Bacteria	2|Bacteria	S	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_4
AMEPOAEB_01362	657322.FPR_30120	0.0	939.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
AMEPOAEB_01363	665956.HMPREF1032_01010	3.46e-27	102.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
AMEPOAEB_01364	657322.FPR_05150	4.65e-194	539.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,3WGVX@541000|Ruminococcaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
AMEPOAEB_01365	657322.FPR_05160	9.24e-143	409.0	COG3266@1|root,COG3266@2|Bacteria,1USV4@1239|Firmicutes,24VT3@186801|Clostridia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01366	748224.HMPREF9436_02789	0.0	1378.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
AMEPOAEB_01367	657322.FPR_30170	4.61e-153	450.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
AMEPOAEB_01368	657322.FPR_30180	6.9e-129	365.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3WJGJ@541000|Ruminococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
AMEPOAEB_01369	657322.FPR_30190	2.18e-216	597.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
AMEPOAEB_01370	657322.FPR_30200	1.07e-299	820.0	COG0144@1|root,COG0144@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
AMEPOAEB_01371	657322.FPR_30210	7.85e-31	117.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WGYF@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
AMEPOAEB_01372	657322.FPR_30210	3.72e-189	528.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WGYF@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
AMEPOAEB_01373	657322.FPR_30220	1.45e-181	504.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
AMEPOAEB_01374	657322.FPR_30230	0.0	1163.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
AMEPOAEB_01375	657322.FPR_30240	1.59e-211	584.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
AMEPOAEB_01376	657322.FPR_24560	0.0	1098.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3WGHR@541000|Ruminococcaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
AMEPOAEB_01377	657322.FPR_24570	7.41e-65	197.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3WKB9@541000|Ruminococcaceae	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
AMEPOAEB_01378	657322.FPR_24580	2.71e-72	217.0	2E9SM@1|root,333YT@2|Bacteria,1VNW8@1239|Firmicutes,25BUJ@186801|Clostridia,3WS91@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01379	748224.HMPREF9436_01043	8.77e-131	374.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
AMEPOAEB_01380	657322.FPR_11420	1.58e-66	209.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,3WSC6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
AMEPOAEB_01381	657322.FPR_11430	4.95e-57	176.0	COG1251@1|root,COG1251@2|Bacteria,1W1DD@1239|Firmicutes,25EHF@186801|Clostridia,3WSM6@541000|Ruminococcaceae	186801|Clostridia	C	Hydrid cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
AMEPOAEB_01382	411483.FAEPRAA2165_02494	1.06e-135	386.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3WKA4@541000|Ruminococcaceae	186801|Clostridia	S	SAM-dependent methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
AMEPOAEB_01383	657322.FPR_11450	1.22e-173	485.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
AMEPOAEB_01384	657322.FPR_11460	0.0	1135.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3WG7T@541000|Ruminococcaceae	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
AMEPOAEB_01389	657322.FPR_01410	2.53e-147	414.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WM48@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,HTH_31,Peptidase_S24
AMEPOAEB_01390	411489.CLOL250_01915	2.48e-25	95.9	2DNMA@1|root,32Y3J@2|Bacteria,1VJCJ@1239|Firmicutes,24RI7@186801|Clostridia,36Q0E@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01391	657322.FPR_01390	2.72e-173	482.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3WH52@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase, YaeB family	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
AMEPOAEB_01392	657322.FPR_01380	6.97e-208	575.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3WJR3@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AMEPOAEB_01393	657322.FPR_01370	5.66e-119	347.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGC7@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
AMEPOAEB_01394	657322.FPR_10690	2.51e-197	547.0	COG5578@1|root,COG5578@2|Bacteria,1UK80@1239|Firmicutes,25FQ0@186801|Clostridia,3WM07@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
AMEPOAEB_01395	657322.FPR_10680	2.58e-167	468.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WI78@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
AMEPOAEB_01396	657322.FPR_10670	4.01e-184	511.0	2DJT4@1|root,32UDS@2|Bacteria,1VDA1@1239|Firmicutes,24SD3@186801|Clostridia,3WK3G@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01398	657322.FPR_10650	1.8e-247	680.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
AMEPOAEB_01399	657322.FPR_17940	1.37e-247	681.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3WI1X@541000|Ruminococcaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
AMEPOAEB_01400	657322.FPR_17950	3.18e-118	341.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3WJK5@541000|Ruminococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
AMEPOAEB_01401	657322.FPR_17960	0.0	1149.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
AMEPOAEB_01402	657322.FPR_12660	8.53e-249	685.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type branched-chain amino acid transport systems periplasmic component	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
AMEPOAEB_01403	657322.FPR_12650	3.12e-193	538.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3WGTF@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
AMEPOAEB_01404	657322.FPR_12640	7.11e-231	637.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3WHKQ@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
AMEPOAEB_01405	657322.FPR_12630	4.52e-200	554.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3WH2I@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type branched-chain amino acid transport systems ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
AMEPOAEB_01406	657322.FPR_06430	1.87e-216	597.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	AA_kinase,HTS
AMEPOAEB_01407	657322.FPR_06440	5.78e-213	587.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,3WHUR@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
AMEPOAEB_01408	657322.FPR_06450	8.86e-127	359.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3WIDH@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
AMEPOAEB_01409	748224.HMPREF9436_02320	2.61e-162	461.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,3WGAX@541000|Ruminococcaceae	186801|Clostridia	H	Pyridoxal kinase	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
AMEPOAEB_01412	657322.FPR_28190	4.3e-103	304.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WIDR@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
AMEPOAEB_01413	411483.FAEPRAA2165_03375	8.74e-141	399.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3WHKU@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter, permease protein	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
AMEPOAEB_01414	657322.FPR_28210	6.12e-184	511.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WH9D@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
AMEPOAEB_01415	657322.FPR_28220	0.0	867.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01416	657322.FPR_15880	4.71e-107	318.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
AMEPOAEB_01417	657322.FPR_15870	4.91e-78	233.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3WJG0@541000|Ruminococcaceae	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
AMEPOAEB_01418	657322.FPR_15860	1.11e-282	773.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WH1M@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
AMEPOAEB_01419	748224.HMPREF9436_01317	3.93e-83	259.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,249DU@186801|Clostridia,3WKV2@541000|Ruminococcaceae	186801|Clostridia	S	Pfam:TPM	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
AMEPOAEB_01420	657322.FPR_15830	3.29e-159	448.0	295NP@1|root,2ZT02@2|Bacteria,1W38K@1239|Firmicutes,2569B@186801|Clostridia,3WQQ1@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01421	657322.FPR_15820	1.61e-63	204.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
AMEPOAEB_01422	657322.FPR_30250	1.94e-79	239.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
AMEPOAEB_01423	657322.FPR_18390	1.04e-195	551.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01424	657322.FPR_18400	5.84e-312	849.0	COG0151@1|root,COG0151@2|Bacteria,1TRIN@1239|Firmicutes,24B1S@186801|Clostridia,3WNA3@541000|Ruminococcaceae	186801|Clostridia	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_3,GARS_A
AMEPOAEB_01425	657322.FPR_18410	9.93e-204	561.0	COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,2494P@186801|Clostridia,3WJ6V@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
AMEPOAEB_01426	657322.FPR_18420	1.58e-193	535.0	COG2819@1|root,COG2819@2|Bacteria,1UY7T@1239|Firmicutes,25BJ8@186801|Clostridia	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
AMEPOAEB_01427	657322.FPR_18430	1.09e-69	219.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3WGDG@541000|Ruminococcaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
AMEPOAEB_01428	748224.HMPREF9436_02912	6e-105	313.0	2APHA@1|root,31EK9@2|Bacteria,1VIZ2@1239|Firmicutes,258XE@186801|Clostridia,3WKUY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U4
AMEPOAEB_01429	657322.FPR_20660	6.54e-157	441.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3WGM5@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
AMEPOAEB_01430	657322.FPR_20650	1.37e-173	485.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3WGQ0@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
AMEPOAEB_01431	657322.FPR_20640	1.24e-47	152.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,3WKHX@541000|Ruminococcaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
AMEPOAEB_01432	657322.FPR_20630	1.32e-131	373.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24JF9@186801|Clostridia,3WJRT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
AMEPOAEB_01433	657322.FPR_14590	8.41e-81	243.0	COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,24EKV@186801|Clostridia,3WM22@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
AMEPOAEB_01434	411483.FAEPRAA2165_01540	6.31e-150	422.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia,3WHIR@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
AMEPOAEB_01435	657322.FPR_14610	1.29e-129	368.0	COG1309@1|root,COG1309@2|Bacteria,1V7CM@1239|Firmicutes,24K3K@186801|Clostridia,3WMJU@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AMEPOAEB_01436	657322.FPR_14620	1.38e-58	186.0	2C176@1|root,2ZD1S@2|Bacteria,1W5ZC@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01437	657322.FPR_14630	6.41e-154	434.0	COG0484@1|root,COG0484@2|Bacteria,1UWW2@1239|Firmicutes,25CGC@186801|Clostridia,3WJ1B@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
AMEPOAEB_01438	657322.FPR_14640	2.75e-136	389.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3WINQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01439	411483.FAEPRAA2165_03369	8.36e-266	744.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
AMEPOAEB_01440	657322.FPR_24520	9.51e-240	659.0	COG1077@1|root,COG1077@2|Bacteria,1U7BF@1239|Firmicutes,24CEA@186801|Clostridia,3WI36@541000|Ruminococcaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
AMEPOAEB_01441	657322.FPR_24530	7.34e-59	184.0	2ECK3@1|root,336I7@2|Bacteria,1VG26@1239|Firmicutes	1239|Firmicutes	C	decarboxylase gamma	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
AMEPOAEB_01442	657322.FPR_24540	2.13e-276	757.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3WH3E@541000|Ruminococcaceae	186801|Clostridia	C	decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
AMEPOAEB_01444	657322.FPR_29360	2.33e-125	356.0	COG1896@1|root,COG1896@2|Bacteria,1UIAE@1239|Firmicutes,25EFH@186801|Clostridia,3WSPD@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
AMEPOAEB_01445	657322.FPR_29350	2.21e-100	291.0	2FDXA@1|root,345XQ@2|Bacteria,1VYRW@1239|Firmicutes,253D4@186801|Clostridia,3WQHI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01446	657322.FPR_29340	1.02e-190	528.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3WIZJ@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
AMEPOAEB_01447	657322.FPR_29330	6.8e-115	329.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24J98@186801|Clostridia,3WJY6@541000|Ruminococcaceae	186801|Clostridia	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
AMEPOAEB_01449	657322.FPR_10950	1.12e-212	587.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,24AYF@186801|Clostridia,3WJHN@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
AMEPOAEB_01450	657322.FPR_10970	0.0	1045.0	COG3675@1|root,COG3675@2|Bacteria,1VCNZ@1239|Firmicutes,24U5I@186801|Clostridia,3WQ4X@541000|Ruminococcaceae	186801|Clostridia	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
AMEPOAEB_01451	657322.FPR_10980	4.01e-91	268.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3WMN1@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
AMEPOAEB_01452	657322.FPR_10990	1.3e-36	123.0	2CHQ1@1|root,32YKW@2|Bacteria,1VG7A@1239|Firmicutes,24RG3@186801|Clostridia,3WKVF@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01453	657322.FPR_09170	0.0	1318.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3WGZ0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
AMEPOAEB_01454	657322.FPR_09160	1.47e-54	170.0	2E36Q@1|root,32Y6E@2|Bacteria,1VEZV@1239|Firmicutes,24MQP@186801|Clostridia,3WKJK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	-	-	-	-	-	-	-	-	-	-	-	-	DUF370
AMEPOAEB_01455	657322.FPR_09150	1.64e-213	593.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WHXU@541000|Ruminococcaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
AMEPOAEB_01457	657322.FPR_25850	8.66e-227	624.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3WJFU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
AMEPOAEB_01458	657322.FPR_25840	1.4e-206	572.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,3WH28@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
AMEPOAEB_01459	657322.FPR_25830	8.2e-214	592.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
AMEPOAEB_01460	657322.FPR_01980	8.11e-152	426.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3WHYJ@541000|Ruminococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
AMEPOAEB_01461	657322.FPR_01970	1.45e-161	452.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3WGED@541000|Ruminococcaceae	186801|Clostridia	OU	Psort location Cytoplasmic, score	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
AMEPOAEB_01464	657322.FPR_10030	3.3e-117	344.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3WHB1@541000|Ruminococcaceae	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
AMEPOAEB_01465	657322.FPR_10040	2.72e-189	525.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3WIGB@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
AMEPOAEB_01466	657322.FPR_10050	6.15e-40	131.0	2EGE3@1|root,33A60@2|Bacteria	2|Bacteria	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01467	657322.FPR_10060	1.18e-211	590.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3WIV4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
AMEPOAEB_01469	657322.FPR_03010	2.77e-296	817.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGVQ@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
AMEPOAEB_01470	657322.FPR_03000	0.0	1243.0	28N4Z@1|root,2ZBA9@2|Bacteria,1V60W@1239|Firmicutes,24HJB@186801|Clostridia,3WP63@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01471	742741.HMPREF9475_02248	2e-88	262.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,21YZU@1506553|Lachnoclostridium	186801|Clostridia	KT	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
AMEPOAEB_01472	537013.CLOSTMETH_02541	0.0	1266.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WGBM@541000|Ruminococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
AMEPOAEB_01473	748224.HMPREF9436_00880	4.47e-53	168.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJYT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
AMEPOAEB_01474	657322.FPR_20350	2.31e-194	540.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGNS@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_01475	411483.FAEPRAA2165_01400	5.49e-29	114.0	2E33N@1|root,32Y3S@2|Bacteria,1VFAP@1239|Firmicutes,24R1K@186801|Clostridia,3WMAX@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
AMEPOAEB_01477	657322.FPR_20380	8.79e-24	97.4	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia,3WS5Y@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AMEPOAEB_01478	657322.FPR_20380	8.88e-182	511.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia,3WS5Y@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AMEPOAEB_01479	657322.FPR_20390	3.65e-291	795.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
AMEPOAEB_01480	657322.FPR_20400	1.63e-300	819.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
AMEPOAEB_01482	657322.FPR_29660	1.32e-135	389.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3WG8N@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
AMEPOAEB_01483	657322.FPR_29670	0.0	1152.0	COG0305@1|root,COG0358@1|root,COG0305@2|Bacteria,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
AMEPOAEB_01484	657322.FPR_29680	1.52e-241	665.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
AMEPOAEB_01485	657322.FPR_29890	7.16e-173	482.0	COG3279@1|root,COG3279@2|Bacteria,1UYHU@1239|Firmicutes,24CBK@186801|Clostridia,3WRIR@541000|Ruminococcaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
AMEPOAEB_01486	411483.FAEPRAA2165_02465	4.24e-292	801.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
AMEPOAEB_01487	657322.FPR_29870	3.01e-187	521.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,3WHAC@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
AMEPOAEB_01488	657322.FPR_29860	1.64e-54	172.0	COG3874@1|root,COG3874@2|Bacteria,1V6H7@1239|Firmicutes,24JJ5@186801|Clostridia,3WJU2@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YtfJ	ytfJ	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
AMEPOAEB_01489	748224.HMPREF9436_01804	0.0	1394.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WH5Y@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
AMEPOAEB_01490	748224.HMPREF9436_01702	2.12e-14	68.9	COG0847@1|root,COG0847@2|Bacteria,1V0CE@1239|Firmicutes,24AR6@186801|Clostridia,3WQ12@541000|Ruminococcaceae	186801|Clostridia	L	K02342 DNA polymerase III subunit epsilon	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas2CT1978,RNase_T
AMEPOAEB_01491	657322.FPR_15530	1.3e-138	392.0	2DKU6@1|root,30BEK@2|Bacteria,1V5I4@1239|Firmicutes,24HYE@186801|Clostridia,3WPJ9@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR_assoc	casE	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
AMEPOAEB_01492	657322.FPR_25720	1.31e-218	604.0	COG0469@1|root,COG0469@2|Bacteria,1TQC0@1239|Firmicutes,24CHE@186801|Clostridia,3WMZU@541000|Ruminococcaceae	186801|Clostridia	H	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
AMEPOAEB_01493	657322.FPR_25730	2.22e-131	372.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3WIK0@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoesterase	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
AMEPOAEB_01494	657322.FPR_25740	1.75e-294	806.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WGJC@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01495	657322.FPR_14780	7.83e-145	419.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24Z3A@186801|Clostridia,3WMZ9@541000|Ruminococcaceae	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
AMEPOAEB_01496	657322.FPR_14790	5.51e-263	721.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3WGFH@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
AMEPOAEB_01497	657322.FPR_14800	3.05e-311	855.0	COG1589@1|root,COG1589@2|Bacteria,1VKJ9@1239|Firmicutes,24RT5@186801|Clostridia,3WSDS@541000|Ruminococcaceae	186801|Clostridia	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
AMEPOAEB_01498	657322.FPR_31410	6e-165	463.0	COG0561@1|root,COG0561@2|Bacteria,1V8Z5@1239|Firmicutes	1239|Firmicutes	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
AMEPOAEB_01499	657322.FPR_31400	2.25e-76	228.0	COG1555@1|root,COG1555@2|Bacteria,1UQNT@1239|Firmicutes,258F9@186801|Clostridia,3WMJR@541000|Ruminococcaceae	186801|Clostridia	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
AMEPOAEB_01500	657322.FPR_31390	0.0	1542.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
AMEPOAEB_01501	657322.FPR_05200	7.02e-183	510.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes,24F20@186801|Clostridia,3WMR7@541000|Ruminococcaceae	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
AMEPOAEB_01503	657322.FPR_20610	5.93e-304	827.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3WGYP@541000|Ruminococcaceae	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
AMEPOAEB_01504	657322.FPR_20600	9.23e-307	835.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3WGMN@541000|Ruminococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
AMEPOAEB_01505	657322.FPR_20590	1.13e-215	594.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia,3WHCY@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
AMEPOAEB_01506	657322.FPR_20580	1.61e-67	211.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3WGDX@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
AMEPOAEB_01508	657322.FPR_31570	8.09e-33	117.0	COG2261@1|root,COG2261@2|Bacteria,1VKCP@1239|Firmicutes,24U0Q@186801|Clostridia,3WR89@541000|Ruminococcaceae	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
AMEPOAEB_01509	657322.FPR_31560	9.08e-166	463.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
AMEPOAEB_01510	657322.FPR_31550	2.02e-308	840.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
AMEPOAEB_01511	657322.FPR_31540	7.02e-94	273.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3WKYJ@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
AMEPOAEB_01512	657322.FPR_27710	1.42e-254	703.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
AMEPOAEB_01513	657322.FPR_27720	2.57e-222	613.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3WI74@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
AMEPOAEB_01514	657322.FPR_27730	8.76e-71	216.0	2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
AMEPOAEB_01515	748224.HMPREF9436_00960	6.76e-120	348.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,3WHY1@541000|Ruminococcaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
AMEPOAEB_01516	657322.FPR_27750	2.21e-51	162.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3WKJ9@541000|Ruminococcaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
AMEPOAEB_01517	657322.FPR_16160	9.23e-214	590.0	COG1175@1|root,COG1175@2|Bacteria,1TT6K@1239|Firmicutes,249DR@186801|Clostridia,3WIAZ@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
AMEPOAEB_01518	657322.FPR_16150	0.0	883.0	COG1653@1|root,COG1653@2|Bacteria,1UZ65@1239|Firmicutes,24BTH@186801|Clostridia,3WICF@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
AMEPOAEB_01519	657322.FPR_16130	3.5e-101	298.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,24BR4@186801|Clostridia,3WJ0Q@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
AMEPOAEB_01520	657322.FPR_16120	4.41e-155	436.0	COG0670@1|root,COG0670@2|Bacteria,1V6E1@1239|Firmicutes,25CU4@186801|Clostridia,3WSEF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
AMEPOAEB_01521	657322.FPR_16110	9.2e-268	732.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
AMEPOAEB_01522	657322.FPR_14970	0.0	1236.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WHGV@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_01524	657322.FPR_14690	7.9e-130	369.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WJC4@541000|Ruminococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
AMEPOAEB_01525	657322.FPR_14680	8.47e-77	232.0	COG0431@1|root,COG0431@2|Bacteria,1UK51@1239|Firmicutes,25FKA@186801|Clostridia,3WN56@541000|Ruminococcaceae	186801|Clostridia	C	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
AMEPOAEB_01526	657322.FPR_14660	0.0	1643.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3WRX8@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	lacZ	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
AMEPOAEB_01527	657322.FPR_14650	8.61e-89	260.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,3WKJ0@541000|Ruminococcaceae	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01528	657322.FPR_03960	9.5e-296	814.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
AMEPOAEB_01529	657322.FPR_03950	9.83e-205	567.0	COG2755@1|root,COG2755@2|Bacteria,1VCJD@1239|Firmicutes,25B7F@186801|Clostridia,3WS5V@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
AMEPOAEB_01530	657322.FPR_03940	2.57e-64	196.0	2DG94@1|root,337GI@2|Bacteria,1VHDH@1239|Firmicutes,24RH0@186801|Clostridia,3WKWR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01531	657322.FPR_03930	9.28e-76	232.0	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24MNV@186801|Clostridia,3WJTE@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01532	411483.FAEPRAA2165_01685	4.7e-38	131.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3WGN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
AMEPOAEB_01533	657322.FPR_02990	3.19e-27	106.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
AMEPOAEB_01534	657322.FPR_02980	7.21e-286	784.0	COG1143@1|root,COG1145@1|root,COG1143@2|Bacteria,COG1145@2|Bacteria,1VE78@1239|Firmicutes,25DNA@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
AMEPOAEB_01535	657322.FPR_02970	0.0	1159.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WH64@541000|Ruminococcaceae	186801|Clostridia	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
AMEPOAEB_01536	657322.FPR_03980	1.06e-280	768.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3WGMK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
AMEPOAEB_01537	657322.FPR_03970	1.27e-272	746.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WGVY@541000|Ruminococcaceae	186801|Clostridia	E	aminotransferase class V	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
AMEPOAEB_01538	748224.HMPREF9436_00082	4.37e-182	510.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WGTZ@541000|Ruminococcaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
AMEPOAEB_01539	657322.FPR_09020	8.33e-184	511.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,2488X@186801|Clostridia,3WINS@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the ParB family	noc	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
AMEPOAEB_01540	657322.FPR_09030	2.05e-165	462.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WIRQ@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
AMEPOAEB_01541	657322.FPR_09040	0.0	1159.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3WGGQ@541000|Ruminococcaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
AMEPOAEB_01542	657322.FPR_05360	1.82e-203	565.0	28VFF@1|root,2ZHI0@2|Bacteria,1VDDA@1239|Firmicutes,24PH9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01543	657322.FPR_05350	5.62e-293	800.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3WIJX@541000|Ruminococcaceae	186801|Clostridia	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
AMEPOAEB_01544	411483.FAEPRAA2165_01265	4.98e-101	295.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,3WKCP@541000|Ruminococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
AMEPOAEB_01545	657322.FPR_11880	4.17e-39	139.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3WG9F@541000|Ruminococcaceae	186801|Clostridia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
AMEPOAEB_01546	657322.FPR_11890	1.58e-200	555.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
AMEPOAEB_01547	657322.FPR_11900	1.01e-124	355.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3WI2S@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
AMEPOAEB_01548	657322.FPR_11910	2.3e-83	246.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WK31@541000|Ruminococcaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
AMEPOAEB_01549	657322.FPR_11920	2.1e-268	736.0	COG2199@1|root,COG2199@2|Bacteria,1V2R7@1239|Firmicutes,24GA5@186801|Clostridia,3WKMH@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
AMEPOAEB_01550	748224.HMPREF9436_03314	6.88e-230	646.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGTD@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_01551	657322.FPR_12160	0.0	1123.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
AMEPOAEB_01552	657322.FPR_12150	7.87e-49	163.0	COG1826@1|root,COG1826@2|Bacteria,1VHQF@1239|Firmicutes,24QW5@186801|Clostridia	186801|Clostridia	U	mttA/Hcf106 family	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
AMEPOAEB_01553	748224.HMPREF9436_00295	4.52e-157	444.0	COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,24KCD@186801|Clostridia	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
AMEPOAEB_01555	657322.FPR_02380	2.86e-241	672.0	2DRD9@1|root,33BA4@2|Bacteria,1VQ0D@1239|Firmicutes,24UYQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01557	657322.FPR_02360	0.0	1250.0	2A4BH@1|root,30SX6@2|Bacteria,1V5JA@1239|Firmicutes,24IBE@186801|Clostridia,3WR7A@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01558	657322.FPR_05490	9.66e-59	186.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WKCU@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
AMEPOAEB_01559	657322.FPR_05500	3.17e-235	647.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3WHGJ@541000|Ruminococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
AMEPOAEB_01560	657322.FPR_05510	1.37e-141	399.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
AMEPOAEB_01561	657322.FPR_05520	7.7e-111	320.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3WK3X@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
AMEPOAEB_01562	657322.FPR_05530	4.7e-157	440.0	COG0546@1|root,COG0546@2|Bacteria,1V7EI@1239|Firmicutes,24K0E@186801|Clostridia,3WPBF@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
AMEPOAEB_01563	657322.FPR_16880	2.2e-223	615.0	COG1266@1|root,COG1266@2|Bacteria,1V416@1239|Firmicutes,24MKP@186801|Clostridia,3WMQU@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
AMEPOAEB_01564	657322.FPR_16870	5.4e-63	193.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3WJX0@541000|Ruminococcaceae	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
AMEPOAEB_01565	657322.FPR_16860	1.96e-145	410.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3WKBG@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
AMEPOAEB_01566	657322.FPR_16850	1.59e-288	787.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,3WGD9@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
AMEPOAEB_01567	657322.FPR_10020	0.0	1073.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
AMEPOAEB_01568	657322.FPR_10010	3.91e-194	538.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	ytrP	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GAF_2,GAF_3,GGDEF,HAMP
AMEPOAEB_01569	657322.FPR_03100	3.23e-145	414.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3WH25@541000|Ruminococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
AMEPOAEB_01570	657322.FPR_03090	2.07e-238	656.0	COG0673@1|root,COG0673@2|Bacteria,1UGN1@1239|Firmicutes,249ZU@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
AMEPOAEB_01571	657322.FPR_03080	1.46e-262	720.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
AMEPOAEB_01572	657322.FPR_03070	3.54e-183	512.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,3WG9A@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
AMEPOAEB_01574	657322.FPR_05020	2.22e-185	515.0	2AYHW@1|root,2ZC56@2|Bacteria,1V2NU@1239|Firmicutes,24FWP@186801|Clostridia,3WRIM@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
AMEPOAEB_01576	657322.FPR_05040	1.56e-144	408.0	2C1S2@1|root,2ZJNT@2|Bacteria,1V2MG@1239|Firmicutes,24KZ7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01578	657322.FPR_17910	1.33e-118	340.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3WITH@541000|Ruminococcaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
AMEPOAEB_01580	411483.FAEPRAA2165_00209	7.93e-157	446.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,3WII8@541000|Ruminococcaceae	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
AMEPOAEB_01581	657322.FPR_09450	1.01e-156	440.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3WJ7J@541000|Ruminococcaceae	186801|Clostridia	E	Serine dehydratase beta chain	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
AMEPOAEB_01582	657322.FPR_09440	1.93e-302	826.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
AMEPOAEB_01583	657322.FPR_09430	1.95e-164	461.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,24AEX@186801|Clostridia,3WH0U@541000|Ruminococcaceae	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
AMEPOAEB_01585	657322.FPR_06000	6.44e-283	774.0	2DF4U@1|root,2ZQGY@2|Bacteria,1UFDY@1239|Firmicutes,251JV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01586	657322.FPR_06010	8.69e-96	279.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WK7G@541000|Ruminococcaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
AMEPOAEB_01587	742738.HMPREF9460_02834	1.52e-170	495.0	COG3451@1|root,COG3451@2|Bacteria,1TS2J@1239|Firmicutes,25EI6@186801|Clostridia,26AGB@186813|unclassified Clostridiales	186801|Clostridia	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
AMEPOAEB_01588	1007096.BAGW01000014_gene1097	1.14e-138	407.0	COG0791@1|root,COG0791@2|Bacteria,1VUWD@1239|Firmicutes,24JFU@186801|Clostridia,2N8X1@216572|Oscillospiraceae	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01589	742738.HMPREF9460_02840	5.43e-17	75.9	2EA8K@1|root,330PF@2|Bacteria,1VFGQ@1239|Firmicutes,24S35@186801|Clostridia,26CE4@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01590	742738.HMPREF9460_02841	2.4e-97	298.0	28JW4@1|root,2Z9KZ@2|Bacteria,1TQH3@1239|Firmicutes,24E6K@186801|Clostridia,26AFY@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01592	657322.FPR_29020	2.15e-300	818.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3WGJ7@541000|Ruminococcaceae	186801|Clostridia	J	Methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
AMEPOAEB_01593	657322.FPR_19890	0.0	1396.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WSRM@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
AMEPOAEB_01594	657322.FPR_19920	1.53e-287	785.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,2483N@186801|Clostridia,3WK0W@541000|Ruminococcaceae	186801|Clostridia	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
AMEPOAEB_01595	657322.FPR_19910	3.67e-294	803.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3WHYK@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
AMEPOAEB_01596	411483.FAEPRAA2165_01829	4.13e-71	220.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
AMEPOAEB_01597	657322.FPR_20930	3.64e-24	100.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1TT1Q@1239|Firmicutes,249N4@186801|Clostridia,3WHHS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
AMEPOAEB_01598	657322.FPR_20920	1.32e-217	600.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3WH7J@541000|Ruminococcaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
AMEPOAEB_01599	657322.FPR_20910	0.0	1165.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
AMEPOAEB_01600	657322.FPR_10000	4.27e-45	148.0	2BRQ4@1|root,32KPS@2|Bacteria,1V8GJ@1239|Firmicutes,24JFQ@186801|Clostridia,3WKHT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01601	657322.FPR_09990	6.87e-229	629.0	COG1208@1|root,COG1208@2|Bacteria,1UIRX@1239|Firmicutes,25EQU@186801|Clostridia,3WHF0@541000|Ruminococcaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
AMEPOAEB_01602	657322.FPR_09980	4.2e-114	327.0	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,25EFE@186801|Clostridia,3WJW3@541000|Ruminococcaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
AMEPOAEB_01603	657322.FPR_09970	4.77e-82	243.0	COG2169@1|root,COG2169@2|Bacteria,1UK9A@1239|Firmicutes,25FR9@186801|Clostridia,3WS6K@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
AMEPOAEB_01604	657322.FPR_09960	6.15e-114	329.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3WIXN@541000|Ruminococcaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
AMEPOAEB_01605	657322.FPR_13620	2.08e-209	579.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WHZV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
AMEPOAEB_01606	657322.FPR_13630	5.67e-277	758.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3WGXA@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
AMEPOAEB_01607	657322.FPR_29900	9.68e-178	503.0	COG3290@1|root,COG3290@2|Bacteria,1UZ59@1239|Firmicutes,24A0V@186801|Clostridia,3WMIF@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
AMEPOAEB_01608	657322.FPR_29910	8.94e-100	289.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3WIXA@541000|Ruminococcaceae	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
AMEPOAEB_01609	657322.FPR_29920	2.2e-224	618.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
AMEPOAEB_01610	657322.FPR_29930	2.18e-133	380.0	COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,24C86@186801|Clostridia,3WJ26@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
AMEPOAEB_01611	748224.HMPREF9436_00857	1.54e-152	456.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
AMEPOAEB_01612	657322.FPR_05000	0.0	890.0	COG3581@1|root,COG3581@2|Bacteria,1TRVV@1239|Firmicutes,24947@186801|Clostridia,3WH15@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
AMEPOAEB_01613	657322.FPR_04990	5.44e-225	619.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes	1239|Firmicutes	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01614	748224.HMPREF9436_01413	3.76e-30	108.0	2DRCI@1|root,33B7V@2|Bacteria,1VKC1@1239|Firmicutes,24S49@186801|Clostridia,3WQWC@541000|Ruminococcaceae	186801|Clostridia	S	SPP1 phage holin	-	-	-	-	-	-	-	-	-	-	-	-	Holin_SPP1
AMEPOAEB_01615	742740.HMPREF9474_02333	8.96e-63	196.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,220XF@1506553|Lachnoclostridium	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
AMEPOAEB_01616	748224.HMPREF9436_03320	5.39e-72	218.0	COG3108@1|root,COG3108@2|Bacteria	2|Bacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
AMEPOAEB_01618	657322.FPR_13550	4.26e-196	550.0	COG5492@1|root,COG5492@2|Bacteria,1VKK8@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Laminin_G_3,SLH
AMEPOAEB_01621	180332.JTGN01000008_gene4058	7.79e-23	114.0	COG4926@1|root,COG4926@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,Prophage_tail
AMEPOAEB_01622	748224.HMPREF9436_00699	3.73e-305	881.0	COG1511@1|root,COG5412@1|root,COG1511@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WJR8@541000|Ruminococcaceae	186801|Clostridia	D	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
AMEPOAEB_01624	936375.HMPREF1152_0686	1.92e-19	82.4	2EQ24@1|root,33HNI@2|Bacteria,1VNBA@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01625	748224.HMPREF9436_00696	1.06e-79	242.0	COG5492@1|root,COG5492@2|Bacteria,1V2Y7@1239|Firmicutes	1239|Firmicutes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01626	748224.HMPREF9436_00695	2.38e-58	182.0	2DZTF@1|root,32VIH@2|Bacteria,1VDAA@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01628	748224.HMPREF9436_00693	2.21e-63	194.0	2E3I6@1|root,32YGN@2|Bacteria,1VG2Z@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01630	748224.HMPREF9436_03335	2.59e-155	441.0	29MEK@1|root,308CG@2|Bacteria,1U37V@1239|Firmicutes,24B5H@186801|Clostridia,3WI9A@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01631	748224.HMPREF9436_03336	4.68e-83	250.0	2DNUY@1|root,32ZA9@2|Bacteria,1VEH6@1239|Firmicutes,25NTG@186801|Clostridia,3WQG8@541000|Ruminococcaceae	186801|Clostridia	S	Phage minor structural protein GP20	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
AMEPOAEB_01633	748224.HMPREF9436_01469	1.72e-119	359.0	COG5529@1|root,COG5529@2|Bacteria,1VD4M@1239|Firmicutes,24HPC@186801|Clostridia,3WRMZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,zf-trcl
AMEPOAEB_01634	748224.HMPREF9436_01468	1.93e-281	776.0	2C9AC@1|root,2Z839@2|Bacteria,1TPQF@1239|Firmicutes	1239|Firmicutes	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
AMEPOAEB_01635	748224.HMPREF9436_01467	2.05e-289	795.0	COG4626@1|root,COG4626@2|Bacteria,1TQR2@1239|Firmicutes,251MW@186801|Clostridia,3WR4Z@541000|Ruminococcaceae	186801|Clostridia	S	phage terminase, large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
AMEPOAEB_01637	748224.HMPREF9436_01465	1.31e-72	218.0	2FHW6@1|root,349PA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01638	748224.HMPREF9436_01463	2.57e-36	128.0	29XBZ@1|root,30J1S@2|Bacteria,1URU1@1239|Firmicutes,259RF@186801|Clostridia,3WQJA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01641	411471.SUBVAR_05838	3.37e-116	354.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
AMEPOAEB_01643	748224.HMPREF9436_00638	4.47e-66	205.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJAP@541000|Ruminococcaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
AMEPOAEB_01655	1519439.JPJG01000059_gene1909	8.49e-12	61.6	2EU1H@1|root,33MII@2|Bacteria,1VNHJ@1239|Firmicutes,24WGU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01659	997346.HMPREF9374_3915	2.37e-13	65.5	2DRQ9@1|root,33CK9@2|Bacteria,1VKDT@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
AMEPOAEB_01660	748224.HMPREF9436_01793	2.68e-75	233.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WM48@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,HTH_31,Peptidase_S24
AMEPOAEB_01661	768726.HMPREF9178_1091	0.000927	48.1	2E37J@1|root,32Y79@2|Bacteria,1VI5W@1239|Firmicutes,4HP73@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01662	1118057.CAGX01000042_gene563	2.96e-182	514.0	COG1256@1|root,COG1256@2|Bacteria,1UMAS@1239|Firmicutes	1239|Firmicutes	N	bacterial-type flagellum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01663	927704.SELR_20830	5.67e-76	229.0	COG3654@1|root,COG3654@2|Bacteria,1VENF@1239|Firmicutes	1239|Firmicutes	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
AMEPOAEB_01664	411471.SUBVAR_05816	4.65e-62	209.0	COG0582@1|root,COG0582@2|Bacteria,1TSN5@1239|Firmicutes,248E3@186801|Clostridia,3WPTB@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
AMEPOAEB_01665	748224.HMPREF9436_01979	1.55e-125	361.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3WK2R@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
AMEPOAEB_01666	657322.FPR_27680	0.0	1204.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3WGUK@541000|Ruminococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
AMEPOAEB_01667	657322.FPR_27690	1.29e-105	305.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
AMEPOAEB_01668	657322.FPR_27700	9.92e-149	418.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3WHAR@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
AMEPOAEB_01669	657322.FPR_16830	0.0	1923.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
AMEPOAEB_01672	657322.FPR_08730	5.25e-129	366.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,3WK6H@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
AMEPOAEB_01673	657322.FPR_08740	1.31e-303	830.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,3WH9E@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01674	657322.FPR_08750	9.55e-30	116.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,3WPGY@541000|Ruminococcaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
AMEPOAEB_01675	657322.FPR_28170	2.43e-222	615.0	28JX7@1|root,2Z9MQ@2|Bacteria,1UZRY@1239|Firmicutes,24AWA@186801|Clostridia,3WPXC@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01676	657322.FPR_28160	0.0	984.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3WGSV@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
AMEPOAEB_01677	748224.HMPREF9436_00453	2.59e-102	300.0	COG4657@1|root,COG4657@2|Bacteria,1VE3F@1239|Firmicutes,24PA9@186801|Clostridia,3WM1P@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
AMEPOAEB_01678	657322.FPR_17760	1.04e-161	454.0	COG4660@1|root,COG4660@2|Bacteria,1VNRD@1239|Firmicutes,24WZ3@186801|Clostridia,3WS16@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
AMEPOAEB_01679	657322.FPR_17750	4.91e-241	662.0	COG4658@1|root,COG4658@2|Bacteria,1V59Z@1239|Firmicutes,24HKP@186801|Clostridia,3WJIV@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the NqrB RnfD family	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
AMEPOAEB_01680	657322.FPR_17740	6.9e-132	376.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
AMEPOAEB_01681	657322.FPR_17730	1.61e-227	634.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,3WSMC@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
AMEPOAEB_01682	657322.FPR_03060	1.79e-128	395.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WHMA@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
AMEPOAEB_01683	657322.FPR_19820	6.61e-46	157.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia,3WRX3@541000|Ruminococcaceae	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
AMEPOAEB_01684	657322.FPR_19830	0.0	1328.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
AMEPOAEB_01685	657322.FPR_19840	4.23e-106	306.0	COG0454@1|root,COG0456@2|Bacteria,1V4FY@1239|Firmicutes,25E88@186801|Clostridia,3WJBZ@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
AMEPOAEB_01688	411471.SUBVAR_05063	0.0	967.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
AMEPOAEB_01689	411471.SUBVAR_05062	8.88e-138	399.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
AMEPOAEB_01691	748224.HMPREF9436_02536	8.48e-84	251.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia,3WMS0@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
AMEPOAEB_01692	657322.FPR_02400	1.74e-140	395.0	COG4333@1|root,COG4333@2|Bacteria,1V8CT@1239|Firmicutes,24K6U@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1643)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1643
AMEPOAEB_01693	657322.FPR_02410	0.0	1194.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,3WSBH@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
AMEPOAEB_01694	657322.FPR_02410	1.95e-40	146.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,3WSBH@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
AMEPOAEB_01695	411483.FAEPRAA2165_02932	6.09e-128	367.0	COG2129@1|root,COG2129@2|Bacteria,1V0W0@1239|Firmicutes,24A73@186801|Clostridia,3WJ04@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
AMEPOAEB_01696	748224.HMPREF9436_02532	3.2e-44	145.0	2BACE@1|root,323SU@2|Bacteria,1UH7E@1239|Firmicutes,257YA@186801|Clostridia,3WKG9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01698	657322.FPR_12250	8.47e-224	617.0	COG0847@1|root,COG0847@2|Bacteria,1UK7S@1239|Firmicutes,25FPM@186801|Clostridia,3WSNQ@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
AMEPOAEB_01699	657322.FPR_12260	2.23e-157	441.0	COG0398@1|root,COG0398@2|Bacteria,1V7VE@1239|Firmicutes,24NGJ@186801|Clostridia	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
AMEPOAEB_01700	657322.FPR_12270	1.12e-219	607.0	COG0544@1|root,COG0544@2|Bacteria	2|Bacteria	D	peptidyl-prolyl cis-trans isomerase activity	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
AMEPOAEB_01703	657322.FPR_28690	2.35e-187	523.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3WI9V@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3
AMEPOAEB_01704	748224.HMPREF9436_00109	7.66e-175	494.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
AMEPOAEB_01705	411483.FAEPRAA2165_01623	2.24e-45	145.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
AMEPOAEB_01706	657322.FPR_18110	4.59e-175	489.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3WGVA@541000|Ruminococcaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
AMEPOAEB_01707	657322.FPR_18120	2.81e-242	669.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3WGV1@541000|Ruminococcaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
AMEPOAEB_01708	657322.FPR_18130	5.27e-118	339.0	2BCB7@1|root,325WH@2|Bacteria,1VU5S@1239|Firmicutes	657322.FPR_18130|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01709	657322.FPR_14890	6.27e-167	468.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
AMEPOAEB_01710	657322.FPR_14880	7e-215	594.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
AMEPOAEB_01711	657322.FPR_14870	3.44e-226	625.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3WRV6@541000|Ruminococcaceae	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
AMEPOAEB_01712	657322.FPR_03720	5.64e-51	162.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WIYY@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
AMEPOAEB_01713	657322.FPR_03730	8.33e-182	506.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3WIQ9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
AMEPOAEB_01714	748224.HMPREF9436_02359	3.63e-216	603.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3WIM4@541000|Ruminococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
AMEPOAEB_01715	657322.FPR_16520	3.91e-159	467.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24C9R@186801|Clostridia,3WH8M@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
AMEPOAEB_01716	657322.FPR_16510	9.58e-232	641.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3WIFV@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
AMEPOAEB_01718	657322.FPR_21260	3.3e-126	358.0	2EDD1@1|root,3379C@2|Bacteria,1W2ES@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01719	657322.FPR_21250	0.0	1065.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3WGE9@541000|Ruminococcaceae	186801|Clostridia	G	Mannitol dehydrogenase	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
AMEPOAEB_01720	657322.FPR_21240	2.21e-172	484.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,247RB@186801|Clostridia,3WGRF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
AMEPOAEB_01721	657322.FPR_06290	2.15e-25	102.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
AMEPOAEB_01722	657322.FPR_06300	7.69e-115	328.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WIGV@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
AMEPOAEB_01723	657322.FPR_06310	1.84e-261	716.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3WG9H@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
AMEPOAEB_01724	748224.HMPREF9436_03308	2.87e-170	476.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WGJA@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
AMEPOAEB_01725	657322.FPR_06330	5.87e-109	318.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3WHWM@541000|Ruminococcaceae	186801|Clostridia	P	acid ABC transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
AMEPOAEB_01726	657322.FPR_13660	5.49e-166	483.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3WGDU@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
AMEPOAEB_01727	657322.FPR_13650	0.0	917.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
AMEPOAEB_01728	657322.FPR_13640	1.04e-66	214.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
AMEPOAEB_01729	657322.FPR_02060	1.45e-85	256.0	COG0739@1|root,COG0739@2|Bacteria,1V7NW@1239|Firmicutes,24K65@186801|Clostridia	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
AMEPOAEB_01730	657322.FPR_02070	6.78e-243	672.0	COG2271@1|root,COG2271@2|Bacteria,1TQZE@1239|Firmicutes,25E40@186801|Clostridia,3WP80@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
AMEPOAEB_01731	657322.FPR_02080	8.75e-152	426.0	COG1309@1|root,COG1309@2|Bacteria,1TWE4@1239|Firmicutes,24C3H@186801|Clostridia,3WM9Z@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AMEPOAEB_01732	657322.FPR_21280	3.37e-182	508.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24FGY@186801|Clostridia,3WRMJ@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
AMEPOAEB_01733	657322.FPR_21270	0.0	969.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3WHGB@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
AMEPOAEB_01734	657322.FPR_18320	3.8e-165	464.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3WGF0@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565	AA_kinase
AMEPOAEB_01735	657322.FPR_18330	1.33e-294	803.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iHN637.CLJU_RS10560	Aminotran_3
AMEPOAEB_01736	657322.FPR_18340	1.31e-216	598.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3WG9U@541000|Ruminococcaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
AMEPOAEB_01737	657322.FPR_12020	2.34e-88	259.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,3WKK1@541000|Ruminococcaceae	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
AMEPOAEB_01738	411483.FAEPRAA2165_03465	7.23e-51	160.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3WJXE@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
AMEPOAEB_01739	657322.FPR_12040	3.02e-228	628.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3WGRE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
AMEPOAEB_01740	657322.FPR_12050	1e-110	324.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
AMEPOAEB_01741	314265.R2601_13514	1.77e-106	345.0	2A5G6@1|root,30U67@2|Bacteria,1RD7R@1224|Proteobacteria,2U8Y0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01742	657322.FPR_06620	7.94e-311	851.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGNN@541000|Ruminococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
AMEPOAEB_01743	657322.FPR_06630	4.87e-114	337.0	COG3940@1|root,COG3940@2|Bacteria,1VAX9@1239|Firmicutes,24NY2@186801|Clostridia,3WKE6@541000|Ruminococcaceae	186801|Clostridia	G	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
AMEPOAEB_01744	657322.FPR_06640	2.67e-196	546.0	2EP6H@1|root,33GT7@2|Bacteria,1VPJU@1239|Firmicutes,24X7H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01751	525254.HMPREF0072_1311	6.12e-19	92.0	29R5M@1|root,30C6X@2|Bacteria,1V4R3@1239|Firmicutes,249E1@186801|Clostridia,22H5X@1570339|Peptoniphilaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01754	657322.FPR_16380	3.63e-115	330.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,24MBJ@186801|Clostridia,3WRU8@541000|Ruminococcaceae	186801|Clostridia	K	Putative ATPase subunit of terminase (gpP-like)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
AMEPOAEB_01755	748224.HMPREF9436_01406	2.93e-172	542.0	2F01Z@1|root,33T5S@2|Bacteria,1V42D@1239|Firmicutes,24HTR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01757	657322.FPR_15040	2.99e-139	393.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3WIEP@541000|Ruminococcaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
AMEPOAEB_01759	657322.FPR_24500	1.56e-232	640.0	COG3081@1|root,COG3081@2|Bacteria,1TSR5@1239|Firmicutes,25CG3@186801|Clostridia,3WKKZ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	NA37
AMEPOAEB_01760	657322.FPR_24490	6.8e-178	499.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,25CBA@186801|Clostridia,3WSC0@541000|Ruminococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
AMEPOAEB_01761	748224.HMPREF9436_01402	1.06e-165	479.0	2A4BH@1|root,30SX6@2|Bacteria,1V5JA@1239|Firmicutes,24IBE@186801|Clostridia,3WR7A@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01763	748224.HMPREF9436_01404	1.72e-87	263.0	COG3757@1|root,COG3757@2|Bacteria	2|Bacteria	M	lysozyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,CW_binding_1,DUF1906,Glyco_hydro_25,PG_binding_1
AMEPOAEB_01764	411483.FAEPRAA2165_01831	2.95e-268	738.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,3WH3M@541000|Ruminococcaceae	186801|Clostridia	E	Thermophilic metalloprotease (M29)	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
AMEPOAEB_01765	657322.FPR_25750	0.0	878.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3WH5C@541000|Ruminococcaceae	186801|Clostridia	E	amino acid carrier protein	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
AMEPOAEB_01766	748224.HMPREF9436_02515	2.22e-73	229.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	CinA,MoCF_biosynth,Sortase,SpoIID
AMEPOAEB_01767	657322.FPR_02830	0.0	1585.0	COG1216@1|root,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
AMEPOAEB_01768	657322.FPR_06570	5.3e-23	96.3	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
AMEPOAEB_01769	657322.FPR_06580	9.72e-147	414.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WJFE@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
AMEPOAEB_01770	657322.FPR_06590	4.66e-117	335.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3WKS1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
AMEPOAEB_01771	657322.FPR_06600	1.37e-224	620.0	COG0226@1|root,COG0226@2|Bacteria,1VT8I@1239|Firmicutes,24IAW@186801|Clostridia,3WJDA@541000|Ruminococcaceae	186801|Clostridia	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
AMEPOAEB_01773	657322.FPR_13720	1.04e-97	295.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGRQ@541000|Ruminococcaceae	186801|Clostridia	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
AMEPOAEB_01774	657322.FPR_13710	0.0	1021.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WRQU@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
AMEPOAEB_01775	657322.FPR_13700	1.9e-26	96.7	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
AMEPOAEB_01776	657322.FPR_13690	8.74e-62	189.0	COG2161@1|root,COG2161@2|Bacteria,1VJMQ@1239|Firmicutes,24RCK@186801|Clostridia,3WKUK@541000|Ruminococcaceae	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
AMEPOAEB_01777	657322.FPR_10740	8.18e-42	148.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3WGT3@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
AMEPOAEB_01778	657322.FPR_10750	2.3e-115	330.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3WHRC@541000|Ruminococcaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
AMEPOAEB_01779	657322.FPR_10760	9.78e-58	181.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	spiA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	EntA_Immun,HTH_3,Peptidase_M78,Peptidase_S24
AMEPOAEB_01780	657322.FPR_10910	9.88e-197	544.0	COG1573@1|root,COG1573@2|Bacteria,1UY78@1239|Firmicutes,24FDP@186801|Clostridia,3WIWM@541000|Ruminococcaceae	186801|Clostridia	L	DNA metabolism protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
AMEPOAEB_01781	657322.FPR_10920	1.79e-87	268.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia,3WHFC@541000|Ruminococcaceae	186801|Clostridia	L	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
AMEPOAEB_01782	657322.FPR_05560	0.0	869.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
AMEPOAEB_01783	657322.FPR_05550	7.11e-186	522.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,3WH2H@541000|Ruminococcaceae	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
AMEPOAEB_01784	748224.HMPREF9436_00325	2.82e-184	523.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3WNHD@541000|Ruminococcaceae	186801|Clostridia	O	peptidylprolyl isomerase	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
AMEPOAEB_01785	657322.FPR_25780	1.19e-258	709.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
AMEPOAEB_01786	657322.FPR_25790	3.45e-64	196.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3WJZN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
AMEPOAEB_01787	657322.FPR_25800	5.95e-84	248.0	COG1358@1|root,COG1358@2|Bacteria,1VMU4@1239|Firmicutes,24V54@186801|Clostridia	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
AMEPOAEB_01790	748224.HMPREF9436_01406	0.0	1165.0	2F01Z@1|root,33T5S@2|Bacteria,1V42D@1239|Firmicutes,24HTR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01791	411483.FAEPRAA2165_02190	4.88e-06	59.3	COG5492@1|root,COG5492@2|Bacteria,1UJ1J@1239|Firmicutes,24TUE@186801|Clostridia,3WKQ6@541000|Ruminococcaceae	186801|Clostridia	N	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01792	748224.HMPREF9436_00966	3.54e-89	266.0	COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,24MPT@186801|Clostridia,3WJUX@541000|Ruminococcaceae	186801|Clostridia	J	S1 RNA binding domain	yugI	-	-	ko:K07570,ko:K07571	-	-	-	-	ko00000	-	-	-	S1
AMEPOAEB_01793	657322.FPR_27790	4.49e-61	188.0	COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,24WD9@186801|Clostridia,3WMHC@541000|Ruminococcaceae	186801|Clostridia	D	septum formation initiator	-	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
AMEPOAEB_01794	657322.FPR_27780	6.41e-85	253.0	291HZ@1|root,2ZP4H@2|Bacteria,1W64S@1239|Firmicutes,256EU@186801|Clostridia,3WQKY@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01795	428125.CLOLEP_03271	2.86e-09	56.6	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
AMEPOAEB_01796	657322.FPR_27760	2.63e-35	120.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3WKNC@541000|Ruminococcaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
AMEPOAEB_01798	657322.FPR_17640	7.41e-45	145.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
AMEPOAEB_01799	657322.FPR_17630	1.67e-72	218.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
AMEPOAEB_01801	657322.FPR_15570	1.62e-70	213.0	COG2198@1|root,COG2198@2|Bacteria,1TUB8@1239|Firmicutes,24W35@186801|Clostridia	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
AMEPOAEB_01803	657322.FPR_15560	5.65e-160	448.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia,3WJ7R@541000|Ruminococcaceae	186801|Clostridia	E	Vitamin B12 dependent methionine synthase activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
AMEPOAEB_01804	657322.FPR_06070	2.82e-83	246.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3WKPX@541000|Ruminococcaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
AMEPOAEB_01805	657322.FPR_06080	2.59e-311	850.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WH5J@541000|Ruminococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
AMEPOAEB_01806	657322.FPR_06090	2.26e-49	157.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3WJSQ@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
AMEPOAEB_01807	657322.FPR_09690	1.85e-19	84.0	COG1309@1|root,COG1309@2|Bacteria,1VJYD@1239|Firmicutes,24SNN@186801|Clostridia,3WP6U@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
AMEPOAEB_01808	657322.FPR_09700	4.26e-189	549.0	COG5263@1|root,COG5263@2|Bacteria,1V1J6@1239|Firmicutes,24G0Y@186801|Clostridia	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
AMEPOAEB_01809	97138.C820_00139	4.02e-17	84.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,36GJ7@31979|Clostridiaceae	186801|Clostridia	K	lacI family	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
## 1574 queries scanned
## Total time (seconds): 272.92828011512756
## Rate: 5.77 q/s