LOCUS       c00108_gnlPro..        14717 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FJGLOEFC_108.
ACCESSION   c00108_gnlPro..
VERSION     c00108_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:21:45
            Original ID  :: gnl|Prokka|FJGLOEFC_108
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14717
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..138
                     /locus_tag="ctg108_1"
                     /transl_table=11
                     /translation="SGGLLISLAKEEAPGLLDKLKASGLPAEIVGEVLEKAEPEILVTN
                     "
     protocluster    1..14717
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1267:4717]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1268..4717
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14717
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14717
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             338..970
                     /locus_tag="ctg108_2"
                     /transl_table=11
                     /translation="MIKVNAIGDACPIPVVKTKNAIRELQGGGTVETLVDNEIAVQNLT
                     KMANQKGYDVHSEKVADNEFKVTMTVNAEAAQIAANSAVATIEEEKCPITPLNKKNIVV
                     VIRSNQMGNGEEELGKALLKGFIYALSQQDTLPSTILFYNSGAYITCEDSASIEDLKSL
                     EAQGVEILTCGTCLNFYGITDKLQVGEVTNMYVIAEKMTQADLIVQP"
     CDS             987..1226
                     /locus_tag="ctg108_3"
                     /transl_table=11
                     /translation="MLRKKKPAFIIAFDATTQAMATDKLCAKNGLPGRLIPVPREITAG
                     CGFAWKAAPEDETILIEALTKEGIEWASTHILEI"
     CDS             1268..2041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_4"
                     /sec_met_domain="BcrAD_BadFG (E-value: 3e-53, bitscore:
                     172.8, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKYFIGIDIGSTCAKTVVMNHEKEILHRFLQPTGWSSVDTANQI
                     QELLREKGILPEESVVVATGYGRVSVPYAAKCVTEITCHAKGACYIHKSETMLLIDIGG
                     QDTKIIRIENGMVTDFLMNDKCSAGTGRFLEVMANTLSLTPQDLCELASKGSGTSISSM
                     CTVFAESEVISLIGRGESRENIAFAVIDSIVQKVVSQAVRLTNGQEECICLTGGLCDYS
                     YLKKSLGESLKTDVLTDTDGRYAGAIGAAIAATTI"
     CDS             2098..3231
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg108_5"
                     /sec_met_domain="Aminotran_5 (E-value: 8.7e-92, bitscore:
                     299.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIYFDNAATTLHKPHEVIEAVVHAMTTAGNASRGTHTGSLAASRT
                     VYETRKKIADFFHCSRADHVIFTSNSTEALNIAICGTLGKGDHIISTDLEHNSVLRPLY
                     HLEEQGASLTFLSANKKGCIDYDDFKRSIKPNTKAIVCTHASNLTGNVLDIERIGRIAK
                     AHNLLFIVDASQSAGCIEINMETMNIDILCFTGHKGLLGPQGTGGLCIHESVEIRPFKH
                     GGSGIHSYEKGQPQAYPARLEAGTLNSHGIAGLCVAINYINTITIPVIAKKEQELLWHF
                     YKGICNIPEIHIYGDFDTKERAAILSLNIEGYDSGTVSDLLSQEYDIATRPGAHCAPRM
                     HQALGTTETGAVRFSFSSFNTMEEVETAIQALKELVE"
     CDS             3443..4717
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg108_6"
                     /sec_met_domain="HGD-D (E-value: 2.7e-88, bitscore: 288.6,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDYVSMWKDLGMDLENHDLLCQVLPTAVGDVFLSQENRPKAMDF
                     WDLVISEVHGIRPAELIKEQEKGRKVFGTFCVYVPDEVVIAANGIVTGLCGGSQFWVPD
                     GEKVLPKSTCPLVKASVGARLGRTCPFFRIADMYVGETTCDAKKKAYEILGEDVPMHIM
                     DVPQMKRTKDIVKWKEEIADFAKVVEEFTGNAITPEKLSEAIHIVNEKRKAMQRVYDCR
                     KSECLPISGRDVLLMTQISFFDDPVRCAEMCNRLADELEQRIKDGVSVVKEGTKRILVT
                     GTPMSVPNWKLHNIIETSGGAVVCEEMCTGTRYFENFVDESKTTLDEQFMALSERYMKT
                     NCACFTPNTGRIDDLLRMVKEYKIDGVIDCSLKFCCLYDTEKYSVSRALKEAGIPVLSL
                     ETDYADTDAEQLRTRIGAFIEMLND"
     CDS             4710..4982
                     /locus_tag="ctg108_7"
                     /transl_table=11
                     /translation="MIKGGLKYYILFENYEQGLALHDVLDSDDIPNRIAPAPRAIQGEL
                     SCGMSLLIEPAHIEQVRLSIEKHQAEYYTIVPLEGQVKPKRDKYC"
     CDS             complement(5090..6190)
                     /locus_tag="ctg108_8"
                     /transl_table=11
                     /translation="MQTGNLQKSTVRMDRTFQEKVMHEVKLLEGRGLSRQLHFTNVKLS
                     EGNAKKRDFRHWSDSGREWREVIVEAAVSDKYLHRDSGKVIHESIYPHGSILLRQSRHI
                     RHNEVGEKDRQKEQRFYSKYSEIFCPSCGAQIQLKGDETNCPYCGGFIQSNFYDWQIED
                     FMIYQTPDPNMDNLKYTSVTILLSFLPTFPCVYLITNMYIAIGVAMTLTIILSLSLLWI
                     RARKIDELENLEKEIVRYDEGWLTSNINEALYKTLLTPELLSYSVNNIKLKGVENTSDK
                     TTISVEAMLRQTFLQNNKHIVTKSEKHNWKLCRSRYPNRIKSKGQAVVMEKECPSCGAN
                     YIPDNNGCCSYCGYSLQVDNAKWKLL"
     CDS             complement(6486..7340)
                     /locus_tag="ctg108_9"
                     /transl_table=11
                     /translation="MKTKTDYKSILIEINILTIAIAIIAVAVYFFLVPSHTSISSMSGL
                     GIVLSNFVPLPLSAITMILNVVLLIIGFFTCGKEFGLKTVYTSVMLPVFLGIFENIFPN
                     IGSITDSQELDVLCYILVVSVGLSILFNRNASSGGLDIVAKIINKYFHMELGKAMSLSG
                     MCVALSAALVYDKKTVVLSVLGTYFNGIVLDHFIFDHNIKRRVCIITKKEEELRQFIVH
                     DLHSGATIYEAIGAYNMEKRNEIITIVDKGEYQKLMKYINQEDPEAFITVYTVSDMRYL
                     PKK"
     CDS             complement(7878..8186)
                     /locus_tag="ctg108_10"
                     /transl_table=11
                     /translation="MNQESRVINVHLEKKEKRDYLVFEFEDAVEVCLNDDESQNTLKAV
                     FVKLLEEVIKESVELNFVEKPEYKTGLYIDVCKEYIKDLNKEIASVRKNMPEKLKLK"
     CDS             complement(8161..10299)
                     /locus_tag="ctg108_11"
                     /transl_table=11
                     /translation="MKIDLHCHTKKVKKGDASTRNVTSDKFFQKVVEAEVKIIAITNHN
                     QFDYVQYKEFKKITEGYCDIWPGVELDIIGKIDQVGNGKRGHLIVIANPKNVELFNDRV
                     QKLIKDEDVNTFQVSVKKVYEMLGECDCIYIPHFHKEPKLSDEDIQELGELLQDSSRLF
                     KETSDYRSLGVFSNFDYSVIIGSDVQDWNKYETSRFADIRLPIQTFEQFCLLAKKDTQI
                     IDTLLNQKRKKEILVSPYKRVSFKLPFYEDINIIFGQKGTGKTEILESLKKYYAENGIP
                     VESYKGSEKDADFSKMLKIDDIIATPEKLRLDSMKQQFIEIYDWKEELPTSFEKYISWM
                     ETKDNNKNKGRMKITECVHIEEEVRNRKLELDYKYLKEFVESTFKKIDIEKYLDKEDSE
                     TLTSILEKLCKNINNAKLQKWNSDKSIKLTNWSIDKIKAIADKCSDTISKPSSVGFYDF
                     AMERFKLFENVEEICSAFSVPDRIEKEYLGNIEEKGDIYIQTRYRMLTKESRTNEFKCG
                     ITILKNCKLAIDEIRSSLLKENISEEISKFQEFYEEGIKDIGVFIGVSKEIALENGEIY
                     KPSNGERGILLMQRLLDSESDVYILDEPELGMGNSYITSNILPKLTDLAKRRKTVIIAT
                     HNANIAVGTLPYISILRTHENGVYKTYIGNPFYDELKNIEDESDTKNWTQESMHTLEGG
                     KSAFYDRKDIYESGKQSD"
     CDS             complement(10397..11365)
                     /locus_tag="ctg108_12"
                     /transl_table=11
                     /translation="MEKLRVASLFCGCGGTDVGLLGDFDFLGKHYASNSMEIVYANDID
                     DNACNIFKENFGIAPDNRDIREVKSEDIPEFDILTGGFPCQSFSIIAQNPKRLGVKDER
                     GKLFFEMCRILKERQPKCFIAENVKGILTANKKSAFPLIMKEFEDSGYNVQYRILNSAN
                     YGVPQKRERVIIVGFRKDLEMEFSFPDTKIRNEDDFIPLKEVIEKKVDEKYFFSERAVA
                     GMMKKRESMNKGRAQDLNKPCNTVGAHLAKVSLNSTDPVLMEGKRYRRFTPREVARIQS
                     FPEKFELVGSETAQYRALGNAIPPVMFWYVAKAVKEKLENN"
     CDS             complement(11353..12816)
                     /locus_tag="ctg108_13"
                     /transl_table=11
                     /translation="MSVYQIPDEYFFRLHHVRPRFKGDIENVLIYVAEEIVRVGERNTN
                     NFIAEVNEALFQYPGNAHKELKTINNWRTEISALFGFIEHTETTEKPGRRAIELANNQD
                     LVECFKVFLYNFQYPGAHIKPKRVLEQIEQGIKFKPAQYILKLLRYANGGKGNSIGITK
                     PEVCHCIFNDLRVTRDNEGVKNTWKRILDNRERKLTYNQSGDVIRYAGDILDYLEIANL
                     LKTYDSRMYYLNTLEEEAIIKFCESEEWFDKYDKMIECRQGSLEEVKKYSDSWFSYVNR
                     DMKNTDFSTDILSYIASSEEELQQLKENTKNAENVGVKELAKTGEVIETRIAKYYDTFT
                     TKDIGDIGESLVHGHECMRIKLGNREDLIHLIKRIPTQFAVGYDISSVELDERKRYIEV
                     KTTISSKPLHFNRIHLTRNEWNTADSTRDRYYVYRLLLSKTERKLFLLQDPVGLYKSDK
                     INMIPSNGADITFDPKNVGQFEELLTWKN"
     CDS             complement(12794..13870)
                     /locus_tag="ctg108_14"
                     /transl_table=11
                     /translation="METKLNAIDLFCGCGGLSYGFEEAGYNILLGIDNDAKALETFELN
                     HVGAKSICGDITEVTYEKDIKPLIGNKTIDVIIGGPPCQGMSLSGPRKFEDPRNKLYLS
                     YIRLVEEIQPKAFVIENVPGLVTLFKGQIKDSIIQKFRNLGYEIQYRILCAADYGVPQN
                     RKRVVFVGMKKGHFEYPDVVSKTITCGMALSDLPTLENELGSEDVPYLTAIQNDYQKLM
                     RRNSSKVKNHVAANHSERVKKIISMVPDGGNYKNLPEEYRNSRNFHVAWTRFASDKPAP
                     TIDTGHRHHFHYKFNRVPTVRECARLQSFPDDFVFLGNKTQQFRQVGNAVPPLMAKCIA
                     EQLTKALREEEDVSLSNT"
     CDS             complement(13845..14048)
                     /locus_tag="ctg108_15"
                     /transl_table=11
                     /translation="MGCGYMTAGQAAKKWKISQRRVQVLCAEDRINGTFKLGEAWAIPE
                     DAEKPKDNRKVRRDNGNKTKRH"
     CDS             complement(14162..14536)
                     /locus_tag="ctg108_16"
                     /transl_table=11
                     /translation="MEKRIHDKTNGLNYTLQGDYYFPELIIKEEEATYGKYGILRKNYL
                     KEHKSGYYQYLILTGKLTEHLNQIDKEAGEQVEILVKQMAERCGVTEKMREENWMEWVR
                     RMNDIKEKVEEIIRGEILYI"
ORIGIN
        1 tccggtggtc tgctcatttc tcttgcaaaa gaagaggcac ctggtcttct tgacaagtta
       61 aaagcttccg gtcttcctgc tgagattgtc ggagaggttt tggaaaaagc agaaccagaa
      121 attttagtca cgaattaaat gacttctacc tatttagaat ttaaaaaaac acaacctact
      181 cttagaatct ttcttacaaa ataaatacca gaatgattca tagaacatat cagatgtgca
      241 gtaaaagtat ggcttcattg catgacgcac atcttgcagc aagaatgccg agacattctt
      301 tacattcttt ataaatatac aaaatggagg aacaatcatg attaaagtaa atgcaatagg
      361 cgatgcctgc ccaatccccg tagtaaaaac taaaaatgct atccgcgaat tacagggtgg
      421 agggacagtt gagacacttg ttgataatga aattgccgta cagaacctta caaagatggc
      481 taaccaaaaa ggatacgatg tacattctga aaaagttgct gataatgaat ttaaagttac
      541 aatgactgta aatgcagaag cggcacagat tgccgctaat agtgctgtgg caacaataga
      601 agaagagaag tgtccaatta ctccgttaaa taaaaaaaat atagtcgtag ttatccgctc
      661 aaatcagatg ggaaacggcg aagaagaact tggaaaagct ttattaaaag gatttatcta
      721 tgccttaagc cagcaagata ctcttccttc tactatcctt ttctataata gcggtgcata
      781 tatcacttgt gaagactctg cctctattga agatttaaaa tctttagaag cccagggtgt
      841 tgaaatcctc acctgcggaa cctgtttaaa cttttatggc attacagata aattacaggt
      901 tggcgaagtg acaaacatgt atgtgatcgc agaaaaaatg acacaggctg acttaatcgt
      961 acagccttaa ataaaggagt ttacctatgc ttagaaagaa aaagcctgca ttcatcatcg
     1021 catttgacgc aaccacacag gcaatggcaa ccgataaact ctgtgcaaaa aatggtcttc
     1081 ccggacgatt aattcctgtt ccacgcgaaa ttaccgccgg ctgtggcttt gcctggaaag
     1141 ccgctccaga agatgaaact attttaatag aagcactcac aaaagaagga atcgagtggg
     1201 cttctacaca tattttagaa atttaattta ttagcattta aaagaaaaaa tattcaggat
     1261 acttattatg aacaaatatt ttattggtat tgatattggt tctacctgcg cgaaaacagt
     1321 tgtcatgaat catgaaaaag aaattctcca ccgtttttta cagccaactg gctggagcag
     1381 tgtagatact gcaaatcaaa tacaagaact acttagagaa aagggtattc ttccagaaga
     1441 atccgttgtt gtcgcgaccg gatatggacg tgtatccgtc ccttacgctg caaaatgcgt
     1501 cacagaaatt acctgccatg caaaaggggc ctgctatatt cataaaagtg aaactatgct
     1561 cctcattgac atcgggggac aggatacgaa aatcatccgc attgaaaatg gtatggtcac
     1621 cgacttcctc atgaacgata aatgttccgc cggaacaggc cgattccttg aagtcatggc
     1681 aaatacatta tctctaaccc cacaagatct gtgtgagctt gcttcaaaag gcagcggaac
     1741 ttctatcagc tccatgtgta ctgtgttcgc tgaatctgag gtaatcagtt taatcggacg
     1801 tggagaatca agagaaaaca ttgcctttgc cgttatcgac tctatcgtac aaaaagttgt
     1861 atcacaggca gtaagactta caaacggaca ggaagaatgt atctgtctta ctggtggatt
     1921 atgcgattac tcttatctta agaaatcgct cggagaatct ttaaaaacag atgtattaac
     1981 cgatactgac ggtcgctatg ctggagcaat tggtgcagcg attgctgcca ctactatctg
     2041 aattacgatc tatgagaatc caatcacaac ctgactacaa tttacaatga ggatattatg
     2101 atttattttg ataacgcagc taccacgctg cataaaccac acgaagtcat tgaagcagtt
     2161 gtacacgcca tgacgactgc tggcaatgct tcacgcggta cacatactgg ctctcttgcc
     2221 gcttcccgca ctgtttacga aacaagaaaa aagattgctg atttttttca ttgctccagg
     2281 gctgatcatg tgattttcac atcgaattct accgaagcat taaacatcgc tatctgtggt
     2341 acacttggaa aaggggacca tatcatatcg acagatttag aacataattc tgtactacgt
     2401 cccttatatc atctggaaga acagggagca tcccttactt tcctttctgc caataaaaag
     2461 ggatgcatcg attatgatga ttttaaacgt tctataaaac cgaatacaaa agcaattgtc
     2521 tgcacacatg cttccaatct taccggaaat gttttagata ttgagagaat tggtcgtatt
     2581 gcgaaagcac acaatcttct ttttattgtt gatgcttctc aaagtgcagg ctgtatagaa
     2641 attaatatgg aaactatgaa tattgatatt ttatgcttta ccggtcataa gggtctgctc
     2701 ggtccacagg ggaccggggg cttatgcatc cacgaaagtg ttgaaattcg cccatttaaa
     2761 catggcggtt ccggcatcca ttcttatgaa aaagggcagc cacaggctta tcctgcccgg
     2821 ttagaagcag gaactttaaa cagccacggt attgccggac tttgtgttgc gattaattac
     2881 attaatacta ttactattcc tgtcattgcc aaaaaagaac aagagctatt atggcatttt
     2941 tataagggga tttgcaatat tcccgaaata catatttacg gagattttga tacaaaagaa
     3001 agagccgcta ttctttcttt aaatatcgaa ggttacgact ctggaacagt atctgattta
     3061 ctgtcccaag aatacgatat tgccacccgt ccgggcgcac attgtgcccc aagaatgcat
     3121 caggcacttg gcacaacaga aacgggtgct gtccgtttca gcttttcctc gtttaataca
     3181 atggaagaag tagaaactgc gatacaggca ctaaaagagc ttgtagagta ataagtttaa
     3241 aaaactatat tgactgaatc tgtaaatgac tgtgctatag ctactaaaaa aacttataaa
     3301 acaacttaca gaatacaatg tacttttaga atttcccctg tttctgtaaa gttcataaaa
     3361 gcatatatat tgccaaaata acttttcaaa cagacttatt tctaaaaata cattaaaata
     3421 aaaaaagaga ggtattttac ttatgtcaga ttatgtttct atgtggaaag atcttggaat
     3481 ggatcttgaa aatcacgatt tattatgtca ggtactccct actgcagtag gtgatgtttt
     3541 tctcagccag gaaaatcgcc caaaagcaat ggatttctgg gatttagtca tctctgaagt
     3601 acatggtatc cgacctgctg aacttattaa ggagcaggaa aaaggacgta aagttttcgg
     3661 tactttctgt gtatatgtac cagatgaagt cgttatcgcc gcaaacggaa ttgtaacggg
     3721 tctttgcggg gggtctcaat tctgggttcc agatggagaa aaagtacttc caaaaagtac
     3781 ctgtccactt gtaaaagctt ctgttggagc aagacttgga agaacttgtc cattctttcg
     3841 cattgcagat atgtatgttg gtgaaactac ctgtgatgct aagaaaaagg cttacgaaat
     3901 tcttggagaa gatgttccaa tgcatatcat ggatgtccct cagatgaaac gtacaaaaga
     3961 tatcgtaaaa tggaaagaag aaattgccga ctttgcaaaa gttgttgaag aatttacggg
     4021 taatgctatc actccagaaa aactttctga agcaattcac attgtaaatg aaaaacgtaa
     4081 agcaatgcaa cgtgtgtatg actgtcgtaa atcagaatgt ctcccgatct ccggacgaga
     4141 tgttttactt atgacacaga tttctttctt tgacgatccc gttcgttgtg ccgaaatgtg
     4201 taaccgcctt gcagacgaat tagaacagcg tatcaaagat ggcgtatctg ttgtcaaaga
     4261 aggtacaaaa cgtatccttg taaccggaac tcctatgtct gttccaaact ggaaactcca
     4321 taatattatt gaaacaagcg ggggtgctgt tgtctgtgaa gaaatgtgta ccggaacacg
     4381 ttatttcgaa aattttgtag acgaaagcaa gacaacttta gatgaacaat tcatggcatt
     4441 atctgagcgt tacatgaaaa caaattgtgc ttgcttcaca ccaaataccg gtcgtattga
     4501 tgacctttta cgtatggtaa aagaatataa aatagatggc gtcattgatt gcagcttgaa
     4561 attctgctgc ctctacgata ctgaaaaata ctccgtatcc cgcgctttaa aagaagctgg
     4621 catacctgtc ttaagcttag aaactgacta tgcagataca gatgctgaac agcttcgtac
     4681 tcgtattggt gctttcatcg aaatgctcaa tgattaaagg cggattaaaa tattatatct
     4741 tattcgaaaa ctatgagcag ggacttgccc ttcacgacgt cttagattcc gatgacattc
     4801 caaaccgtat tgccccggct cccagagcca ttcagggtga attatcctgc ggtatgtccc
     4861 ttctcataga acctgctcac atagaacaag tacgactttc cattgaaaag caccaagcag
     4921 aatactatac catcgtaccc ctcgaaggac aggtaaaacc aaagagagat aaatattgtt
     4981 gaattactat ttttctagat aacagaaaaa ccccagaaac attgtttctg gggtaaatct
     5041 tacacttgaa cacaagtacc ttgcggtacg atatatatac aaaaacttat tacagcaatt
     5101 tccatttagc attatcaact tgcagactat aaccacaata ggaacaacaa ccgttattat
     5161 ccggaatata gttagcccca caacttggac attccttttc catcacaacg gcctggcctt
     5221 tggacttgat tcgattcgga taacgagatc ggcaaagctt ccagttatgc ttttcacttt
     5281 tcgtcacgat atgcttatta ttttgaagaa aggtttgcct caacatcgct tccacagaaa
     5341 tcgtcgtctt gtcagacgta ttttccacac cttttagctt tatattatta acactgtaag
     5401 aaagcagctc tggggtaaga agtgttttgt acaacgcttc attgatatta cttgttaacc
     5461 agccctcatc ataacggaca atctctttct caagattctc cagctcatct attttccttg
     5521 ctctgatcca aagaagactc agactcagta taattgtaag tgtcatcgca acaccaattg
     5581 caatatacat attcgtgatc aaataaacac aaggaaatgt cggtaaaaac gaaagtaaaa
     5641 tcgttacact ggtatacttt agattatcca tattcggatc tggtgtctga taaatcataa
     5701 aatcttcgat ttgccagtca tagaaattac tctgaataaa gcctccgcaa taaggacagt
     5761 ttgtctcatc accttttaac tgtatctgcg ccccacagct tggacaaaat atttccgaat
     5821 actttgagta aaatctctgc tccttctgcc tgtctttctc tcccacttca ttgtgacgaa
     5881 tatgacggga ctgccgaagc aatatcgacc catgcggata aatcgattca tgaattacct
     5941 taccactgtc tctatgtaaa tatttatcag aaacagcggc ttctacgata acttccctcc
     6001 attcacgtcc tgaatcactc caatgccgga agtctctctt tttggcattc ccttctgata
     6061 acttcacatt cgtaaaatgt agctgccttg ataaacctct tccttcaagc agctttactt
     6121 catgcattac tttttcttga aaagtccgat ccattcttac tgtactcttt tgcaaattac
     6181 cggtttgcat caaagtaagc agctcctcca gaacattcga tatctttttc ggtactttct
     6241 ccgttctcaa agacttcgct tccggttgtg ccaatctttt tttcaccaca aaataccagt
     6301 tacttggcaa aaatcgttca aaattccact ccagtatgcg gcttgcaaca atatacccta
     6361 atgcacaagc ccacacaaat gcaaaaacac tcgcctcact ccatgtaagt ttcatcaaaa
     6421 atcacctcct catatatccg tagattactg cagcaacacc cttttccctc aatgctcaaa
     6481 ttcttctact tcttaggcaa ataccgcata tccgataccg tatatactgt aataaatgcc
     6541 tctggatctt cctgattgat atacttcatc aatttctgat attccccttt gtctacaatg
     6601 gtaatgatct catttctttt ttccatattg taagcaccaa tcgcttcgta aatagttgcc
     6661 ccactgtgca gatcatgaac aataaactgc ctcaattcct cttccttttt tgtaatgata
     6721 cagacccgtc gtttgatatt atgatcaaaa ataaaatgat ccaaaacaat accattaaaa
     6781 taagtgccca atacactgag tactacagtt ttcttatcat aaaccagcgc cgccgaaagt
     6841 gccacacaca tccccgacaa agacatcgct ttccccagct ccatatgaaa atatttattt
     6901 ataatcttag ctacaatatc caatccccca gaagaagcat tccggttgaa taaaatactc
     6961 agacccacac tcaccaccag aatgtagcaa aggacatcca gctcctgact atctgttata
     7021 gaaccgatat tgggaaaaat gttctcaaat atccccagaa acaccggcag cataacactt
     7081 gtgtaaactg ttttaagccc gaattccttc ccacaggtaa aaaatccaat aattaacaaa
     7141 actacattaa gaatcatcgt aatcgctgat aatggcagcg gaacaaaatt cgacagaaca
     7201 atacccagac ctgacatact gctaatcgat gtgtgacttg gaaccagaaa aaagtaaacg
     7261 gcaacagcta taatagcaat tgcgatggta aggatattta tttctatcaa aatagactta
     7321 taatctgtct tcgttttcat attatttttt atctcctcct gtgtcaaact gcaagctttt
     7381 taccactgca acttatctta ttcatattat attcatattg tgaatcgaat acaagcatat
     7441 atttacccat tcttttattc tcctgtatct acttaaaatt cgagaatacc gatatattct
     7501 tgtattttcc cacacaacag aaaaacccca gaaacaagaa gtttccgggg taaatcttac
     7561 gcttgaacac aagtaccttg cggtacgata tatattaaag taattctttt cacttacgtt
     7621 caaagaatgg ctttcgtact aattcgcaaa aaacgctcat aagtactcaa tgccttattc
     7681 agttacaaat tatatgagtt cgtgattact cgatgataga agcaacacat cctgatccta
     7741 cagtacgtcc accttcacgg tatcagaacg ggatattgcc agatgtaaat ggttattttt
     7801 cgtttaattt gtgatgaaaa atatgaattt tttgctgatt ccatggggtt tgggaagatt
     7861 ttgttatcag ggtgttatca ctttagtttt agtttctctg gcatattttt tctcacactt
     7921 gcaatttctt tattcaaatc ttttatatat tctttgcaca catctatata taatcccgtt
     7981 ttatattccg gtttttccac aaaatttagt tcaactgact cttttataac ttcctcaagt
     8041 aactttacaa atacagcttt taaagtattt tgactttcat cgtcattgag gcacacttcc
     8101 actgcatctt caaattcaaa cactaaataa tcccttttct cttttttttc taaatgtaca
     8161 ttaatcactc tgctttcctg attcataaat atcctttcta tcataaaatg cacttttgcc
     8221 accctcaaga gtgtgcatac tttcctgcgt ccaatttttt gtatcgcttt catcctctat
     8281 atttttaagt tcatcataaa atggattacc aatatatgtt ttatatactc cattctcgtg
     8341 tgttcttagt atactaatat atggaagtgt tccaactgca atattagcat tatgtgtcgc
     8401 tataatcact gtttttctac gttttgctag atcagttaat tttggaagta tattagatgt
     8461 tatatatgaa tttcccatcc ctaactctgg ttcatctaaa atatatacgt cactttccga
     8521 atccaataat ctttgcatta gtaaaatccc tcgttctcca ttagatggct tataaatttc
     8581 tccattttct aatgcaattt ctttagatac cccgataaat actcctatat ccttaattcc
     8641 ctcctcatag aactcctgaa attttgatat ttcttctgat atattttcct ttaaaagaga
     8701 gcttcttatc tcgtctatgg caagtttaca attttttaaa atagttatac cacatttaaa
     8761 ttcatttgta cgtgattctt ttgttaacat tcgataacgt gtttgaatgt atatatcccc
     8821 tttttcctca atattaccca aatattcttt ttctattcta tctggtactg aaaatgcgct
     8881 acatatttcc tctacatttt caaataattt gaatctttcc attgcaaaat cataaaatcc
     8941 aacactacta ggcttagata ttgtatctga acatttatct gctattgctt ttatcttatc
     9001 aatgctccaa ttcgtaagct taatgctttt atcactattc catttttgta actttgcatt
     9061 atttatattt ttacataatt tttccaatat cgaagttaaa gtttcactat cttctttatc
     9121 taaatatttt tctatatcaa tttttttaaa tgtagattct acaaattctt ttaaatattt
     9181 ataatctaat tcaagctttc ggttgcgtac ctcctcttct atatgtacac actctgttat
     9241 tttcatcctc cctttatttt tattattatc ttttgtttcc atccagctta tatatttttc
     9301 aaaggatgtt ggtaattctt ctttccaatc ataaatttct ataaactgtt gtttcatact
     9361 atctaatcga agtttttcag gtgtagctat tatatcatca atctttaaca ttttagaaaa
     9421 atctgcatct ttttcgctac ctttgtaact ttctacagga attccatttt cagcataata
     9481 ttttttcaag gattcaagaa tctccgtttt tccggttccc ttttgcccaa aaatgatatt
     9541 tatatcttca taaaaaggta gtttaaaact tactctttta tatggtgata ctaagatttc
     9601 ttttttgcgt ttttgattaa gcaatgtgtc tatgatttgt gtatctttct tcgccaacaa
     9661 acaaaactgc tcaaaggttt gtataggaag tcttatatca gcaaacctac tggtttcata
     9721 tttattccaa tcttgtacat cacttcctat aataacacta taatcaaaat ttgaaaaaac
     9781 ccctaaactt cgataatcag atgtctcttt aaataaccga ctagaatctt gtaataattc
     9841 ccctaattcc tgaatatctt catcagaaag tttaggttcc ttatgaaaat gcggtatata
     9901 aatacagtca cattctccta acatttcata cacttttttg acactaacct gaaatgtgtt
     9961 tacatcttca tcttttatta atttttgtac tcgatcatta aataattcga catttttagg
    10021 gttagcaatt actatcaaat gacctctctt tccgtttccc acttgatcta ttttccctat
    10081 aatatcaagt tccactcccg gccatatatc acaatatcct tctgtaattt ttttaaattc
    10141 tttatattga acataatcaa attgattatg atttgttatg gcaataattt taacttctgc
    10201 ctcaacaact ttctgaaaaa atttatctga tgtaacgttt cttgtagagg catctccctt
    10261 tttcactttt ttcgtatgac agtgtaaatc tattttcata gttgtattcc tacctatttt
    10321 atataattac cttatcgaca aaaatcctta attctcttac tataatcaca tttctctcat
    10381 tctaattttt ttatcattaa ttattttcta atttttcttt taccgccttg gcaacatacc
    10441 aaaacattac tggcggaatt gcatttccta gtgccctata ttgagcagtt tcacttccta
    10501 caagctcaaa tttttctggg aaagactgta ttcttgctac ctctcttggt gtaaaccttc
    10561 tatatcgctt tccctccata agaactggat ctgtgctgtt taaagatact ttcgctaaat
    10621 gtgctccaac tgtattacat ggtttattta aatcttgagc tcttccttta ttcatactct
    10681 ctcttttttt catcattcct gctacagctc gttcactaaa aaaatatttt tcatctacct
    10741 ttttttctat aacttctttt agtggaataa aatcatcttc gtttctaatc tttgtatctg
    10801 gaaatgaaaa ctccatttct aaatctttgc gaaatccaac gataataaca cgttctcttt
    10861 tttgtggaac accatagttt gcggaattta atatacgata ctgtacatta tatccactat
    10921 cttcaaattc cttcattatt aaaggaaatg cgcttttctt atttgctgta aggataccct
    10981 ttacattttc tgcaataaaa catttaggct gtctttcctt gagaatcctg cacatttcaa
    11041 aaaatagctt tcctctttca tcttttactc caagtcgttt aggattctga gcaataatag
    11101 aaaaagattg acatggaaaa ccaccagtta aaatatcaaa ttctggtata tcctcagatt
    11161 ttacttctcg tatatctcga ttgtctggtg ctattccaaa attttcttta aatatattac
    11221 atgcattatc atcaatatca tttgcataaa ctatttccat actatttgaa gcataatgtt
    11281 tacctaaaaa atcaaaatct cctagcaatc ctacatctgt tccgccacat ccacaaaata
    11341 atgaggctac tcttaatttt tccatgttaa taactcctca aactgtccta catttttagg
    11401 atcaaatgtt atatccgctc cattagaagg tatcatatta attttgtcac tcttataaag
    11461 ccctaccgga tcctgtaata aaaataattt tctttctgtt ttacttaata acaaacgata
    11521 tacataatat ctatcacgtg tactatcagc agtattccac tcatttctcg ttaaatgtat
    11581 tctgttaaag tgtaaaggtt tcgaactaat agttgtttta acttcaatat atctttttct
    11641 ctcatccaat tccactgagc tgatatcata tccaactgca aactgtgtcg gtattctctt
    11701 aattaaatga attaaatcct cacgatttcc taatttaatt cgcatacatt catgcccgtg
    11761 aactaaactt tctcctatat ctccaatatc tttcgttgta aatgtatcat aatattttgc
    11821 aatacgtgtt tcaattacct ctcctgtctt agcaagttct ttcactccca cattttcagc
    11881 attttttgta ttttctttta actgttgcaa ctcttcttca ctgcttgcaa tatacgatag
    11941 aatatctgtt gaaaaatctg tattcttcat atctctattt acatatgaaa accaactatc
    12001 actatacttt tttacttctt ctaagctccc ctgacgacat tctatcatct tatcatattt
    12061 atcaaaccat tcttcagatt cacaaaactt tataatagct tcttcctcaa gtgtattaag
    12121 ataatacatt ctactatcat aagttttaag aagattcgct atttccaaat aatctaaaat
    12181 atcaccggca taacgtataa catctcctga ctgattatat gttaattttc tttcccgatt
    12241 atctaaaatc cttttccagg tgtttttgac tccctcatta tctctagtga ctcgtaaatc
    12301 attaaatatg cagtgacata cctctggttt agtaattcca atggaatttc ctttacctcc
    12361 atttgcatat ctcagcaatt ttaaaatata ctgtgccggc ttaaatttaa ttccttgttc
    12421 aatttgttcc aatactcttt taggtttaat atgtgctccg ggatattgaa aattataaag
    12481 aaatacttta aagcattcta ccaaatcctg attatttgct aactcaattg ctcttcttcc
    12541 aggtttttct gttgtttcag tatgctcgat aaaaccaaac aatgctgata tttctgtacg
    12601 ccaattatta atagttttta attctttatg agcattcccc ggatattgaa acaatgcttc
    12661 atttacttct gcaataaaat tgtttgtgtt tctttctcca actcttacaa tttcttctgc
    12721 aacataaatt aacacatttt ctatatcacc tttaaatctt ggtctaacat gatgaagcct
    12781 aaaaaaatac tcatcaggta tttgataaac tgacatcctc ttcctccctt aacgctttgg
    12841 ttaattgttc tgctatgcat ttggccataa gtggtggaac agcatttcca acttgcctaa
    12901 attgttgtgt cttgtttcct aaaaagacaa aatcatctgg aaatgactgt aatctagcgc
    12961 attccctaac agttggtaca cgattaaatt tataatgaaa atgatgtcta tgtcctgtat
    13021 caattgtagg ggctggttta tcacttgcaa atcttgtcca tgctacatga aaatttctac
    13081 tatttctata ttcttctggt aaatttttat aattacctcc atcaggaacc attgatataa
    13141 ttttctttac tctttctgaa tgattagctg cgacatgatt tttaactttg ctagaatttc
    13201 ttctcattaa tttttgataa tcgttttgta tcgctgtaag atacggtaca tcttcacttc
    13261 ccaactcatt ttctaaagta ggcaaatctg ataatgccat accacacgtt attgtttttg
    13321 aaacaacatc tggatattca aaatgacctt tcttcattcc cacaaacact acacgctttc
    13381 tattctgcgg cacaccataa tcagcagcac acaatattct atattggatt tcatatccta
    13441 aatttctaaa tttttgaata atactatctt taatttgtcc tttaaataaa gtaaccaatc
    13501 ctggcacatt ttcaatcaca aacgctttgg gctgaatttc ctctaccaac cgtatatatg
    13561 ataaataaag tttatttctg ggatcttcaa attttctcgg tcctgataag gacattcctt
    13621 gacaaggagg accgcctata atcacatcta ttgttttatt tccgattaaa ggtttaatat
    13681 ctttttcata tgtcacctct gttatgtctc cacaaattga ttttgctcct acatgattca
    13741 attcaaatgt ttctaaagcc ttagcatcat tatctattcc taataatata ttgtatcctg
    13801 cttcttcaaa tccatatgat aaacctccac aaccacaaaa taaatcaatg gcgtttagtt
    13861 ttgtttccat tatctcttct tacctttcta ttatctttag gtttctctgc atcctctgga
    13921 attgcccatg cctctcccaa cttaaaagtt ccatttatac ggtcttccgc acataaaact
    13981 tgtacccttc gttgagaaat cttccatttt tttgcagctt gccctgctgt catatatcca
    14041 catcccatat ttcttatccc ttctttcttg ttttattata ttctacgggg cgaacaaaag
    14101 caactttata ttttctattt atacaaaatg gagagacaga tttgttgtct ctccattctt
    14161 actaaatata taatatttca cctcttatta tttcctctac tttttcttta atatcattca
    14221 tcctcctcac ccattccatc caattctctt ctctcatttt ttctgtcact ccacaccttt
    14281 ctgccatctg cttcaccagt atttctacct gttctcctgc ctctttatca atctggttca
    14341 gatgctctgt cagctttccg gttaatataa gatattgata ataccctgat ttatgttctt
    14401 tcagataatt ctttctcaat attccatatt tgccataagt tgcttcttcc tctttaatga
    14461 ttagttctgg aaagtaataa tctccctgta aggtatagtt cagaccattc gttttatcat
    14521 gaattcgttt ttccatagtt ctaaatctcc attcccctat atctcgtttt actgcttcgt
    14581 tgatgttgat tttccatcat gctttttctt ttttcctgtt ttagtaattc taaaatactt
    14641 ttccctgatg actgctcctt tctgtttttt tcttcaattt ccatttctct ctgaatatct
    14701 ttttgtatgg cttccct
//
