LOCUS       c00008_gnlPro..        13634 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENGGHBFP_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 03:25:36
            Original ID  :: gnl|Prokka|ENGGHBFP_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13634
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13634
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[144:3634]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      145..3634
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13634
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13634
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(145..912)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.4e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.9e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.5e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(953..2911)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.1e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.4e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAITGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(2933..3634)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.7e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3835..4107
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4110..4925
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(4959..5192)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDEAVILGAVLTVFFPDGD"
     CDS             complement(5624..6331)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             6511..6699
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSIGEFQIRYKLPSKRNNKYEENTDI
                     FNRDGKLCCFLGGSDRF"
     CDS             6656..7366
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGLGSSSLAPSDS
                     SSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNTGTTAAGINLT
                     FSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAPTANTEGDTVT
                     ISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEMVPEPATVSLG
                     LLGLAALMMRRRRA"
     CDS             complement(7584..7718)
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGHYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(7830..8030)
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(8044..9249)
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPVA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9273..10019)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_13"
                     /sec_met_domain="adh_short_C2 (E-value: 2.4e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10148..10666)
                     /locus_tag="ctg8_14"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGTPPGA
                     LRENEEAGQ"
     CDS             complement(10730..12205)
                     /locus_tag="ctg8_15"
                     /transl_table=11
                     /translation="MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITP
                     EMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRP
                     AREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHD
                     RDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFID
                     RFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSY
                     GDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFS
                     QARTENLNPENTVLEEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLS
                     LVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLH
                     VNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             12270..12416
                     /locus_tag="ctg8_16"
                     /transl_table=11
                     /translation="MVISVSLNKVRPAWDFVRFLIVSMVKRGCILPGWKGEGKSRQGGG
                     RHF"
     CDS             12463..13170
                     /locus_tag="ctg8_17"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQPYVQQQMSGLAN
                     AFLALLPPDQASLPVAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPMLVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 gtaacaattt tttacgctgc gcgacgatga ggaagcaact gtctggtatt ttattcctgg
       61 ttcaaggaaa cctggtaatg aaaaaactcc cgacagccga tgccgccggg agtttttaca
      121 gagcgtctta agaaggaatc ttctttagaa acagaggcct tccttggcgt tggcccgcat
      181 gaagtcgcgg ttgaggcggg cgatgttgtc cacgctgatg cctttcgggc aggcggcttc
      241 acattcatac tggttcgtgc agttgccaaa gccttccgct tccatctgct tcatcatggc
      301 caggacgcgc ttggaacgtt ccggctggcc ctgcggcagc agattgagat gggcgatctt
      361 ggcggaggtg aacagcatgg cggaggcgtt tttacaggag gccacgcagg cgccgcagcc
      421 gatgcaggcg gccgcgtcaa aggcggcgtc cgccttcact ttttccacgg cgatgttgtt
      481 ggcgttcggc gcggaaccgg tacgcacgtc aatatagcct ccagcggcga tgatgcggtc
      541 cagggcggag cggtccacca tcaggtcccg caggattggg aaagccttcg cgcggaaggg
      601 ttcaatccag acggtatcgc cgtccttgaa cttgcgcatg tgaagctggc aagtggtcac
      661 ctggcgttcc ggcccgtggg gaatgccgtt gatggtcagg gagcacatgc cacagatgcc
      721 ttcccggcag tcgtggtcaa aatggatggg ttccttgcct tccttgacca ggccttcatt
      781 gacgatgtcc agcatttcca ggaaggaggc gtccaccgga atgtccttgg cggcataggt
      841 ctcaatgcgg cccttggctt cccggttttc ctggcgccag accttgagag tgagattgag
      901 tgttttagcc atgttataat ctttcttttg agtgttaatg tattggctat ctttacttgt
      961 agctgcggat ggcaaggtgc acgttctcga aggtcagcgg ttccttgtgg agaacaggca
     1021 ggctgtccac gccagtgtat tcccaggcgg ctacataggc gtattcatcg tcgttgcgct
     1081 tagcttcgcc gtccggcagc tggtattcca cgcggaagtg ggcgccgcag gattcctggc
     1141 ggttcagggc gtcatagcag agcagctggg cgaattccag gaagtcggcc acgcggcagg
     1201 ctttttccag ttccgcgttg atgccgtccg ccgtgccggt tacgcgcacg ttttcccaga
     1261 attccttgcg gagctgggga atgcgttcaa tggcgtgggt caggctttct tccgtgcggg
     1321 ccatgccgca gtcttcccac ataatgaggc ccagttcccg gtggaaggag tccaccgtct
     1381 tggtgccctt cacattcagg agcttgttga tgcgttcctt cacttcgtct tccgcagcct
     1441 tgaattccgg ggcggcggtg gtgacggcgc cgggtttggt ggtcgtcagg taagcgggca
     1501 gcgtggcggg aatgacgaag tagccgtcag acaggccctg catcagggcg gaggctccca
     1561 ggcggttggc gccgtggtcg gagaagttgg cttcaccgag gacgtgcagc cccttcacat
     1621 tggacatgag gttgtagtcc acccacaggc cgcccatggt gtagtgggag gcggggtaga
     1681 tcatcatggg cgtttcatgg gggtcgtcgt ccgtgatttc ttcgtacatg tcaaacagat
     1741 tgccgtattg gccgtcaatc cattcgcgac ccatgcgctt gatttcatcc gcaaaatcca
     1801 ggaagacgcc cttgccggtg atggccacgc cgcggccgtc gtcgcaggct tccttggcgg
     1861 cgcgggagga aatgtcgcgc ggggccaggt tgccgaagga gggatacttg cgttccaggt
     1921 agtagtcccg ttcttcttcg ggaacatcgg aaggcttgat ttccttttta cggatttttt
     1981 ctgcggtttc acgggacttg ggcacccaga tgcggccgct gttgcggagg gattccgaca
     2041 tcagcgtcag tttggactgg tagtcgccct tgaccggaat gcaggtgggg tggatttgcg
     2101 tgaagcaggg gttggcgaag aaggcaccgc gcttgtaggc cttgtaggcg gcagtgacgt
     2161 tgcagcccat cgcgttggtg gacaggaaga acacgttgcc gtagccgccc gtgcagagca
     2221 ggacggtatc ccctgcgtag gatttgattt cgccggtaac cagattgcgg gtgacgatgc
     2281 ccttggcttc gccgtccacc agcaccagat ccatcatttc atggcgcgag aacatttcaa
     2341 tgtgtccctt ggccacttcc ttttccaggg cctggtaggc acccagcagg agctgctggc
     2401 ccgtctgtcc gcgtgcgtag aaggttcgct tgagctgggc gccaccgaag gagcggttgt
     2461 ccagcaggcc gccgtattca cggccgaagg gaacgccctg ggccacacac tggtcaatga
     2521 tgttggagga gacttccgcc agacggtaga cattggcttc acgggcgcgg aagtcgccgc
     2581 ctttaacggt gtcgtaaaac aggcggtaaa cggagtcgcc gtcgttctgg tagttcttgg
     2641 ctgcgttaat gccgccctgg gccgcaatgg agtgggcgcg gcgggggctg tcctggtagc
     2701 agaagcattt gacgttgtag ccaagttcgg caagcgtggc agcagcggag gcgccagcca
     2761 ggccggaacc taccacaagc accgtgtact tgcgcttgtt gttcggattg atcagtttgg
     2821 actcaagctt gtacttggac catttgtcct gaatagggcc ggagggaatt ttggcatccg
     2881 gcatccagtc gcttacggga aaattaatca tgactttgag aggagttgat ggttatttga
     2941 tgatacccag aagaaccgag accggcacgg agatgaagcc caggcagata atcgcgccgt
     3001 aggcgatggc gataaagttg tagaagggcc ggattttgcg ggaatcgacg cccacagtct
     3061 ggaagatgga ctgtaccccg tggcgcagat ggctgaacag catcagaacg gccaggatgt
     3121 agaaggcgga gcaccatacg ttggaaaatc cggtcacgat catcttgtac acgtcaaagg
     3181 tttccaccgt accgtcggaa atgaaggtgg tgaactgggc ggggtcgtat cctacgcgca
     3241 gggtgtactg gtacaggtgg tagatcagga acaccaggac ggtcagaccg gtatagatca
     3301 tgtagcggga ggagagcgtt gccttgatgg tgttcttgaa cacgtagggt tcgcgggccg
     3361 catggttttc cagcttcagc tggatggtca gccagacgtg gatgatgaag atcaccgcaa
     3421 gccccgcgcg gattccccag agggctgctt ccggcatgga gtgcaggccg tgggcgtagg
     3481 tgttgatcca ttcagggcct ccgaagatga gaaggttgcc tgccaggtgt cccgcaagga
     3541 acaagaccaa acataacccc gtcagagcca caatgatttt gcggccgatg gaggatgtca
     3601 cgaatgtaca tatggttttt actagtgcat tcataggcgc tctaatgaaa taaatgcgtc
     3661 ttcacaggat gcccggttca agcccggatg gcaagcctct tcttgaattt ccggcgcttt
     3721 tcggattttt gaaaagccgg ggaaagagat tgctgtttat cagtttggaa tggttatcat
     3781 tttgttgcct gttccggctt gacgaggctt tccgcatagg cgtatcgtct gtgcatgaaa
     3841 agaagtaaaa aggaagtgct ggacgcggat ttcgcagcgg cgcgcgccgg cgttctggat
     3901 gtggccgcat ttctggaccg ggtggaccgc ggggaagggg aggcggattt ccgttaccat
     3961 gccctgatgg atgttcttcc cctcttatcc gcatccggcc ccggacgcgt ccgggccatt
     4021 ctggaagccc tttcctacag ggatgacacc gtgccggaaa ccgccgcagc caaagcggcc
     4081 tgcggagccc cgaacctcag caaataagaa tgatggcttt catagaacct catatacata
     4141 tggtgtgccg caccacggac gaataccggg ccatggcgca ggccggctgc ctggcggtag
     4201 gggaaccggc gttctgggcc ggttacgacc gttcgtccgc ggacggtttc cgggattatt
     4261 tcgtacagct tacggaatgc gaacccgcca gggcggccaa gttcggcatg gaccattaca
     4321 catggctgtg catcaatccc aaggaggcgc aggacgtggc tttcgcgcgg gatgtaatga
     4381 aactgattcc ggagttcatc gaccggccca atgtcctcgg cattggggaa ataggactga
     4441 accggaatac ttcccatgaa atgactattt ttgaggagca tctggatctg gcggtgcgcc
     4501 tcaaccagct tgtgctgatt cacactcccc atctggaaga caagcttaag gggaccgtaa
     4561 tgattctttc cgccctgaaa aaccgtccgg atctggaccc ttgccgcgtg ctggtggatc
     4621 actgtgagga acataccttc ccgctggtga aggaggccgg ctactgggcc gggctgaccc
     4681 tttatcccac cagcaagctg aatcccaagc gggcggcgga tattctggaa ttgtacggaa
     4741 tggaccgtgt ctgggccaat tccgcggcgg actgggggga ttccgatccc ctggcgctga
     4801 cggccttggc ctgcgagctg cgcaggcgcg gtttttcccg gcaggaaacg gaacgtcttc
     4861 tcctggaaaa tccggagaca ttcatgggac agtccccgaa gttccggaaa gtgtcatccc
     4921 gctaattccg cccgcggcgc ggcggagggt acggccctct agtccccgtc cgggaaaaag
     4981 acggtgagga cggcgcccag gatgaccgcc tcgtcatcca gaaggcccag cctgccgatt
     5041 ccgtcaaaca ggaattcgtc gggagtcagg atgtaggcgc cggcggcggc cagaaggcat
     5101 atattccgtt tgttgaaaaa acgcggttct ccttttctgc ttttgaaata ccggaacagg
     5161 cgcagtagca gctgctgttt ttgaaggttc atggacggga acgggggata aaggttcaag
     5221 ctcagccatt ttcccactcc ttttccctgt ttcggggaag gagtctgttg ccgacggacg
     5281 gaaaccgcag cgatccggac cgtgcgggga aatggattgc tgaaaggatg ggctgttccg
     5341 gatgctgagg gaagccgggc tttgcatgct ccggttccgg ctgtcccggc atgggaaaaa
     5401 ggggcgtgta cggaagtggg gcggggccgg aagctcttga aatgaccctc ccgggggagc
     5461 ctgaatgcca tttccccgtc aagtgctggc cgtgagggta ccgcagcaaa tggaagcttc
     5521 ttcccccctg ttttttccgg cagatgtttg aacggataag gaaaaggccg gctcacgatt
     5581 ttgtgagccg gcctttgaat atagggaggc ggacggtaca ggcttatgcc ctgcggcggc
     5641 gcatcatcag cgcggccagt cccagcaggc ccagggaagc cgtggcgggt tccgggatgc
     5701 tggcgatttc actcatcagt tgaccaactt gttcctggga aaggagggag tcgtgaatgt
     5761 agagctgttc gatggattca gccagtcctg cgtccatgag aatctgatca atttgctggt
     5821 tgccgaattt caggccgctg ttggaatagt acgtagcgct gtctccaaaa tagatgcggg
     5881 tgccaagatc tccggtgact acggaaatgg tcagggaacc ttccgtgccc agcggggtgt
     5941 caacgacggg cccgttgtat gaggtgttgt tccataatcc ctggagtttc cggtccgtgt
     6001 tcaggcccac gccccagctt acactgctgt ttttggcgtt aaacagagcg gtataggtct
     6061 ccggagtgtt gattttggac aggtcaagaa ccatcgtcac agacataacg tcgcggttgt
     6121 tggcaccgta tccgttgaag gttatcccgg acaacgtcag attgctgtcg tcagacgtga
     6181 tggaaacgga atctttccgg gtgccgaaat ccgccgtttg ggaggcaaag tccgaatatc
     6241 ccacgatgga gctatccaac agagcggtag ccgcggtagc gcttaggctc atgccggccg
     6301 aaagaatcag ggtggataat aatttattca tggtcagtat cttaataaaa tgattcaagg
     6361 ttcaatgtat gtacttgtgc ttgaataacg aatttggaat ccgtcaagta atgaaaaaga
     6421 ggccaaatca atcatgaaac caatgaataa caaagactga cccgtcatct tagcaaaagg
     6481 accagagata ttaaaaaatc attattttca atgaattata aatacaatat actaactctt
     6541 aatattttta attgcttgcg gattccaaat tcgattgggg aattccaaat tcgctacaag
     6601 ttgccatcca aaaggaataa taaatatgaa gaaaacactg acatttttaa tcgcgatggg
     6661 aagctttgct gtttcctcgg aggcagcgac cgtttttaat tattacactc ccggtacgga
     6721 taattacaat agtaccatcc atgggtttta tcttggcctg gggtcttctt ccctggctcc
     6781 ttccgattcc tcttctccct cctccctgtc cggagagatc agactggaca gttttacgct
     6841 gcgcggagcc gccaacaatt tgggcgctaa tgtcacttac ggcttcctgg tgctgaatgg
     6901 ctccgacaat tcggtcatcg gctggagcac caatacggga actactgcag cagggattaa
     6961 tctgacgttc agtttttctt ccctggatgg ttctcccctg cttcttgacg cggcattgac
     7021 ataccgtttc ctggccgtga gccagtccgt gatggacttg atgcaggata cgtctaaaac
     7081 gtatttatat gctgcggggg gaacagccgc ccctactgct aacacggaag gagataccgt
     7141 aacgatcagc ggcggattga ctgctcccgg catccgcggc cattatgacg ccgagggagc
     7201 gcctggtgat tctgtcgtta ttacgggagc caacggaacc aatactttca gcttattatc
     7261 cccgattttc acggaaatcc gaggggaaat ggtgccggaa ccagccacgg tttccctggg
     7321 cctgctggga ctggccgcgc tgatgatgcg ccgccgcagg gcttgagctt cctgatggcg
     7381 aaaaatcggc ggatgagagc tgttcttgcg gaacagctct tgttttttat atccagagag
     7441 gaagaattgc ttatccgtat gcgggattca tgccctccgg aaggtacgga atttccgggg
     7501 gcagggggcc gtatccggtt ttttcggcat ggcggcaatt tgctggaaac gtttttgaga
     7561 cgcagtaccg gaaagctttt tctttaccgg aaaatgccgt caaattcggc agcgcgcttt
     7621 tcgtccatat ggtacacggc agctttcaca tagtggcctt tcaggccgga tagggaaccc
     7681 ctttgcagct cacagacctg gagggccgcc gcatacatat tattcgccgt cctattcccc
     7741 ggcgctggta tttcggaaga acggcaatgg gccccatgcc cagcacttca tattcttttc
     7801 catcgtctgc cctgatgacg gacgttgcat caacgatgtt tcccgacgat gcggctgccg
     7861 tggacggcga ctgcatccag ctccgggatg aaggacggac tgacgcgcat gatatggagc
     7921 aggtaatgtt catggcagcc ggggacgaaa tagttccaga acgcttctct cgtgacatgt
     7981 tccgtttcgg catggtctga ggattgttcc gttcttaatg caatggtcat gaaaggttgt
     8041 tctttacggc tcccccttgg agaaattcca gaggcggtgc atcgtcataa tgtccggaat
     8101 gttcatgggg cgcaccacgc ggaacccgat catgcctccg tccgtcaggt accagatgct
     8161 tttagggttt tgaggatcct gacggttcca ggcgggggtg ctggcgcggc gcgcagcgct
     8221 tctcaggctg tccgggtcgt cttcccacga accgccgcga acgatgtgag gggcgccggg
     8281 gatgatgacc aaggggtctt tcgcgggcaa gccgctccgt ttgccgtagg catccggaac
     8341 gtaagagtcc aaaacccatt ccgccacatt tccgtgcatg tcccggagtc cccacttatt
     8401 tggtttttta gagcctgttt tctggtagcg gtcattggag ttgttccagt accaggcgta
     8461 ctggtccaga gaggcttccc cgtttccgta agaataggcg ccgggggagc cggcccggca
     8521 ggcgtattcc cattccgcct ccgtgggcag gcggtagtaa tgcccggtct gggcgctcag
     8581 ccattcgcag aatttgctgg cggcgtggtg ggacatggag atggcgggca gaccgtgttc
     8641 atagccgtgg cccatgccca ggttcatggc ggtgtagggg gcggtaggct gcgtaacgga
     8701 gtcccacagt tcgtcatccg gctgttcctc cagaagctgg ccgtccttgg cgcgcggacg
     8761 cccgttttcc atgaaggccg tataaagttc ccaggggatt tccgtttccg agatccagaa
     8821 gggggagatg ctcactttat gctgcggacc ttcgtccggt ttccggtgcg gctcttccgc
     8881 gggactcccc atgaggaacg ttcctcccgg tatggcgacc atgcgcaggg aagctcccgc
     8941 cacgggaacc gtttccgtgt aggattcaaa acgtgccgga tttccggaag cttcaatgag
     9001 ctgatggatt tggcgcgttg tgccgaccag ctcccgggac ggcaggtcat ccggaatggg
     9061 aagggcagga ccggcagcgc ggtccagttc ccgtttttgc agcgcggatc ggctttctcc
     9121 ccactggcgt gcgctggtaa tgcgcgcggc atcttccgtg gccgggcggg gggaattatt
     9181 ttcttcccgg cacccggcca gcagggcgct tcctcccaga aagcaggaaa caaggaaaat
     9241 gccgcgcatg gaatggagaa aaccggaatg ccctacatcg tcatgcctcc gtcgcaggca
     9301 atgacctgcc cggtgatgta acgggcatcg tcagaggcaa ggaaggccgt cagggcggcg
     9361 atatcttcca cggaaccttg ttctttcaaa ggtattttct taacgatttc ttccttgaga
     9421 ttgtcgggaa tggcattgga catttccgtg gagatgaagc cgggagcaat ggcgttgcac
     9481 gtgactttgc gcggagcgaa ttcctgagcc agtgatttgg tgaaaccgat gagacccgcc
     9541 ttggaagcgg cgtaattggc ctggccgatg ttgccgacga gaccgatgac ggagctcatg
     9601 ttgatgatgc gcccggccgg ggatttcatg agaacgcgct ggagggcctt gaccgtattg
     9661 aacgcgcttt tcaggttggt gtccagaaca gcatcccagt cttcctcttt catgcggagc
     9721 atcagggagt cccgcgtgat gccggcgttg ttcaccagga tgtcaatctg cgggaagtct
     9781 ttcaaaatgg cggccatggt ttcctgaacg gccgcgtaat ccgctacgtc gcaggggtag
     9841 gccttgcagg aatccggaaa ttccttgttg atttcttctg cggccccccc gcagctggat
     9901 ggactgcggc tgatcaggat gaccctggct ccttccgaag cgaagcggcg cgcgacggca
     9961 ttgccgattc cgcggcccgc gccggtaacg atggctgttt tacctgctaa cttttgcatg
    10021 ctgcccacag taaacccgtt tttcacggtt ccggcaagct tgaaatggac ttggccgcgc
    10081 aggaacccat acggggaagg ggcgtgccgg gaatgaaaaa agaggggggg agaaacgggg
    10141 cggggggcta ctgtccggcc tcttcatttt cccggagtgc accggggggc gtcccgtctt
    10201 catccggttc taccaggtcg ctgaattcat ccgaattttc caaaatgtcc tttaaggcgg
    10261 cggaaccgta atagcgggcc tcaaacaggc gtttgccttc ctgcctgcag cggttgtcca
    10321 gcatttccat tcgtttttcc attttttcta tcaaggcgtc ttctttctcc ttttccgcat
    10381 cgttcaattt atcctgaagc tggaggaaat gccggatgtc cttctgaatg tcctgcagcg
    10441 ttttgacggc gttgtccgcg ctttccttgt cctgaacgcc tgccaacgtc tgctggatat
    10501 tgatggcaaa ggaaaaggcc tggttgatca gggattccgc ggaaggaatt ttttccgccg
    10561 gagccgctgc tgcgggggaa gccgttccgg cggccgtttc accaaatgca agagaggctc
    10621 cggacagaag cgcagaatat aagagaggaa caagaaaagc cttcatcctg ttcttttaag
    10681 gcaggatgaa atccacggca aggaaaaagg ggaaactgaa aaaagagcct tattccgccg
    10741 tgatgccgcc tttttcatcg tccagaatgc ctgacttttc cagatagtag tcatatccac
    10801 ctgcgtaggc ggtgatggtc ccccggttca catgcagggt tttttgtgcc agggaacgga
    10861 tgaagtgcac atcgtgggag atgaagacca gtgttccttc ataatgcttc agagcctgca
    10921 ccagggcttc tacggacaaa aggtccaggt gggtggtcgg ctcgtccatc agcaggaggt
    10981 tgggcggatc caccaggaat ttgaccaggc tgagccgcga tttttccccg ccggaaagaa
    11041 cgctgacgcg tttttccaca tccagcctcc ggaacaggaa ggaacccagg atggaacgcg
    11101 cttcttcctc ccggatttca gcgctgcatt tcatgatttc ctccagcacg gtattttccg
    11161 gattcaggtt ttccgttcgc gcctgggaga agtagccgat gcgcgtcgtg gtaccgggag
    11221 tgcgttgtcc ggagtcaatg gggatgatgc ccgccaggat tttgagaaga gtggatttgc
    11281 ccgcgccgtt cgggcctaca agaacagtgc gctccccgcg ttccaccagc aggtccaggt
    11341 tttcataaac cctgcggtcg ccataggatt ggcagacttt ttccagctca atgactttct
    11401 gggtgctgcg cggaggctgg gggaagttga atttaaatac tttcctgcgg gctaccggtt
    11461 tttgaatgat tttcatcttt tccagctgct tgatgcggct ctggacttgc ccggctttgg
    11521 aattgatgga gcggaaacgg tcaataaatt cctgaatgtg cgctatttcc ttctgctggt
    11581 tgcggtaggc cgcctgaagc tgctcgaagc gcacgtcctt ttgttggagg aagtccgagt
    11641 aattgccgcg gtattccacc agttcttcgt tgtcgatgtc gtacacgctt tccaccagct
    11701 catccatgaa atcccggtcg tgggaaatca tcaggatggc tccggggtag tttttcaggt
    11761 atcgctggag ccacagcagg gacaggaggt ccaggtggtt ggtaggttcg tccagcatca
    11821 ggaggtccgg ctccaggaca aggagcttgg ccaggtacgc gcgcatgatc cagccgccgg
    11881 acatttcccg ggcggggcga tggaagtcgc tttcccgaaa ggccagccct ttgagaattt
    11941 tcttggcttt gggctccagc tggtaaccgt tggcggcgtt gaaagtgtca atggcttccg
    12001 cgtattccgg cgtatccgtt ttgttggcgt tttccgccgt ccggatggtg tggatggcct
    12061 gttccatttc cggcgtgatg cccagggcga tttccagaac ggtttcatcc ttcggttcgc
    12121 tggcttcctg gggaagatag cccacgatgg cgtattcatc catgctgatg gagccttcgt
    12181 ccggcgtgtc ttctcccaga atcatgcgga acagggtgga tttgcctgct ccgttggggc
    12241 caaccagagc cacccgttcc ccccagttaa tggtcatttc cgtttccctg aacaaggtcc
    12301 gtccggcgtg ggattttgtg agatttttga tcgtcagcat ggtgaagaga ggatgtattc
    12361 taccgggatg gaaaggggaa ggcaagagcc gtcagggcgg aggcaggcat ttttgaaagc
    12421 tttactggat ttttacgcgt agtctgctag ccttggcgcg ccatgccgac cacgcagaca
    12481 ttcaggcttt tgcttgctgc cgcccttttg tgcggatgga gttcctgctg tactcctccg
    12541 gcggaggatt atatacaaca accttacgtg cagcagcaaa tgtccgggct ggctaatgcc
    12601 ttcctggcgc tgctgccgcc ggatcaggcc tctcttcccg ttgccggagc ggaggccagg
    12661 tggctggcgg acacggccgt ggtccagtcc gcagcgattg cccgggacaa caggactgtg
    12721 ctgtttggct ggctgaacaa tattctggtc aattccaacc tgcgcgacag ggggctgtgc
    12781 tggcaggtcc agcaggattt gtaccgggac ctgcgccgcc gccccgtgaa gtatttccgc
    12841 atagggctga cgattcgaga ccgtggaacg ggcagggagc acagttgcgt gtatgtcaat
    12901 gccgcgggga agggattgca gggctccatt gttctggatg cctggaagaa ctgcgggcat
    12961 ctggtgacgc tgacccagaa ggaccgggaa ggcggcaaat gggaggagga ctggcgggaa
    13021 ccatttgttt ccaaggcctt tccggagggc cattcctacg gcatggaaca tcacctggtc
    13081 tggcccgggt gggccaggaa acgccccatg ctggttcagc ggatattcca gtccgatcag
    13141 cagaatgagg cgaaggcggc cgctgaataa aggggaagcc tgatccggca ggaaccggca
    13201 cacggtgctg cgccgcggcg gtttgcggta tccgccgttt ttaaggaaaa tcccggcgaa
    13261 tcggcaaatg gcggagggaa tccggactca gggcaaataa aaacgcactc agtgcgtaca
    13321 ccgagtgcgg attaattgga taatttgcta gtgttgcagg gcaaaacccc gctgcaaact
    13381 tacttgccct tggcctgcac aaccggagcg ggagcaggag cggtggtttg ctgttgctgc
    13441 tgctgctggg agcaagaagc gaccaggcaa gcggcgccgg cgatggcgag gatagcgatg
    13501 ttcttcataa ttcgaattaa atacagtgtt tgttaactac tggaacctcc gcatccacgg
    13561 aggtttgctg gcaccaatgt aaatggtggc aagtagaaat caagagattt tcttgttcca
    13621 tgtcacggca ttac
//
