LOCUS       c00014_gnlPro..        14521 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHNAJDNK_27.
ACCESSION   c00014_gnlPro..
VERSION     c00014_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 08:33:13
            Original ID  :: gnl|Prokka|CHNAJDNK_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14521
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14521
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[237:4521](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(238..4521)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14521
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14521
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(238..4521)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_1"
                     /sec_met_domain="HGD-D (E-value: 2.1e-60, bitscore: 195.3,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 3.1e-38, bitscore:
                     121.9, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNTLHKLGIDIGSTTVKVAILDQEDHLLFSDYERHFANIQETL
                     SSLLQKAYDALGDFAVAPMITGSGGLTLAKHLGVPFVQEVIAVSTALQHYAPQTDVAIE
                     LGGEDAKIIYFEGGNVEQRMNGICAGGTGSFIDQMASLIQTDATGLNEYAKNYKAIYPI
                     AARCGVFAKTDIQPLINEGATREDLSASIFQAVVNQTISGLACGKPIRGHVAFLGGPLH
                     FLSELKAAFIRTLNLDDEHAITPENSHLFAAIGSALNYKPGETTTLVSLRDRLANGIKM
                     EFEVARMDPLFASQEEYDAFRARHDGHNVKSADLSTYEGNCYLGIDAGSTTTKIALVGE
                     DGSLLYSFYSNNNGSPLATAIRSIKEIYTLLPPKAKIVHSCSTGYGEALLKAALMLDDG
                     EVETVAHFYAAAFFDPEVDCILDIGGQDMKCIKIKNQTVDSVQLNEACSSGCGSFIETF
                     AKSLNYSVQDFAKEALFAKNPIDLGTRCTVFMNSKVKQAQKEGASVADISAGLAYSVIK
                     NALFKVIKLSDASQLGKNIVVQGGTFYNDAVLRSFEKIAGVECVRPDIAGIMGAFGAAL
                     IARERHEAGYQTSMLSIEQINALTFDTKLARCQGCTNHCLLTINRFSGNRQYITGNRCE
                     RGLGKEKNKDNIPNLYEYKNKRLFDYTPLSAEEAARGTVGIPRVLNMYENYPFWATFFK
                     KLGFSVVLSPQSTRKIYELGIDSIPSESECYPAKLAHGHVTWLIHQNVDFIFYPCIPYE
                     RNEFPDSNNHYNCPIVTSYAENIKNNVDEITSGQVKFLNPFMSFASEETLSSQLIKTFG
                     QSEFGIPESEIRDAVAEGWKELAVCRMEMQKKGEEVLQYLKETGRRGIVLAGRPYHIDP
                     EINHGIPELITSYGIAVLTEDSISHLQPVERPLIVMDQWMYHSRLYAAANYVKTRDDLD
                     LIQLNSFGCGLDAVTTDAVNDILTKSGKIYTCLKIDEVNNLGAARIRIRSLISAIRVRE
                     KKQTKRTIVPANYNRVVFTEEMRKNYTILCPQMSPIHFELLEPAFQTAGYNLVVPDVDS
                     RTCVDVGLKYVNNDACYPSLIVVGQLMAAVMSGGYDMSRTAVLISQTGGGCRASNYIGF
                     IRRALEKAGYPDVPVISINLSGLEKNPGFKLTLPLIQHGLYALEFGDIFMRCVYATRPY
                     EAVAGSTDELHEKWKKEVIAFITQKKMLSHGKFKKMCREIIRDFDNLPRKDIKKPRVGV
                     VGEILVKFHPAANNHLVELLESEGAEAVVPDLTDFLLYCFYNTGFKADNLGMSQKSKKI
                     GRLGINFFEWLRSAARDEFTKSRHFTAPAHIDDLARYARDIVSEGNQTGEGWFLTGEML
                     ELIHTGTPNIVCTQPFACLPNHVVGKGVIKELRHRYPGSNIVAIDYDPGASEVNQLNRI
                     KLMLSTANKNLAKQNAPEQKDQAAG"
     CDS             4783..5640
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MNWLNKLERKFGNWAIPNLIVWLIGAYTIGFVLYQVNPSIIGLLM
                     LSPYHILHGQIWRLITWVFMPTDTNLVYLLIMALFYYQLGTTLERTWGTFRFNVYIFGG
                     MLFTVIGAFLLYGIMYLLNGGVTTEMLLIGTSFSTSYINMSIFLAFACMYPDMQVLLMF
                     IIPIKMKWMAAVYGVLIALSFFETGWAGRMAIFMSLLNFIIFFFSTRNLKRYTPHEVHR
                     RQKFKADMRRPQGYAGGAKHKCAVCGRTELDDPTLEFRFCSKCEGNYEYCQDHLFTHQH
                     IRLS"
     CDS             complement(5717..6817)
                     /locus_tag="ctg14_3"
                     /transl_table=11
                     /translation="MAGSTLGTLFKITTWGESHGKGVGVVIDGCPAGLSLCEADIQKFL
                     DRRKPGQSRYATPRKEDDAVEILSGVFEGKTTGTPISLVVFNRNQQSKDYSEIASYYRP
                     GHADYTFDRKYGFRDYRGGGRSSGRETIGRVAAGAVAVKILNELGITFMTYTKSIGPIA
                     VSSGRFDFSEITKNPLYMPDAEAAENAENYLDACMAELNSSGGIVECIIKGMPAGIGDP
                     VFEKLNANLAKAVMSIGAVKGFEIGDGFDVAKATGKNNNDAFVLGEDGRIAKATNHAGG
                     ILGGMSDGSDIILRAAIKPTPSIAATQRTVNQSGEEISVNIKGRHDPIIVPRAVVVVES
                     MAAITIVDALFSNMNARMDMLKKFYS"
     CDS             6942..8267
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="MIEKYLVKKITEPVDWKVTVPGSKSMTNRALLLAALSAGTVRVEG
                     VLFSDDSRHFLACLVALGFTVEIEEEKKCVTVTGCGGRIPSGEAAIDVGSAGTAARFLA
                     AMLGFSDGCYEIRCSAQMKRRPMAELFELLSGAGAKITFLEEEGHLPVRITGCRSARAD
                     ETAGETPRRLSLDITKSTQFLSALLLIAPMVPEGMKIHITSEKTDGSYIRITRKMMQEF
                     GVSVAFDGRDYEVPHRSSYRKEAYTVEPDMSAACYFYAAAAVTGGRALVRHVHMDNTQG
                     DLRFLEVLEHMGCTADDTPEGVLVTGPADGALRGITVNMNDFSDQALTLAAIAPFADAP
                     VRIEGIGHIRGQECDRIHAIQTNLTALGIRCEEEETAVTIYPGSPHGGSVETYDDHRVA
                     MAFSLIGLRTDGIVIENPACCRKTFENYFTVLSELTGKTAED"
     CDS             8435..9532
                     /locus_tag="ctg14_5"
                     /transl_table=11
                     /translation="VHGDIQTPVFMNVGTVAAIKGAVSTEDLEQIKCQVELSNTYHLHV
                     RTGDKLIKEVGGLHKFMSWNRPILTDSGGFQVFSLAGLRKIKEEGVYFHSHIDGAKIFM
                     GPEESMQIQSNLGSTIAMAFDECPPALAERKYVEDSVARTTRWLERCKNEMQRLNGLED
                     TVNRHQMLFGINQGAIYTDIRIDHAKRISELDLDGYAVGGLAVGETHEEMYHVLDETVP
                     YLPVNKPTYLMGVGTPANILEGVERGIDFFDCVYPSRNGRHGHVYTNQGKINLFNQKYE
                     KDMRPIEEGCGCPTCRRYSRAYIRHLLKAKEMLGMRLCVLHNLYFYNTMMEEIRDALDA
                     GNFASYKEEKLYSMGQINREKEMAK"
     CDS             9631..9948
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MFSILATESASSAGWISMVVWLVILFAFMYFFMVRPQKKEQQKKN
                     SMLAELAVGDTILTTSGFYGTVIDIADDTVIVEFGSNKNCRIPMQKAAISAVEKPEDVT
                     E"
     CDS             10037..12532
                     /locus_tag="ctg14_7"
                     /transl_table=11
                     /translation="MKSKKNTLVSRAAVGCVTTAIFLLLCIIKGIYPFGIATLDTVDFQ
                     SQWIPAYYHVWDVLHGDGSAFFDWRVGGGNNFAGVSAQFSLLSPFNLFFLFVKRSWIEK
                     SMIVFLLIKLLVMGYGMRWFLKEQILKEERYGIYILAGSVGYAVNGYTLLYYGMGWLDV
                     AAILPLLCYFFCRMAEREGDWRLGKNTLGYIVCLTLVFLINIPQAYMMCFFLIVFAGGY
                     FFLKRQDQPLKKNGILKFGLTSLLSLGIAAVIFLPAARAMLGSYRLSGEEYRGISGYFL
                     LLRQDGMDAVWKWVILGSVAVPLLFFVISGRRKREHIWQWYLVAAMVLPVFFEAVNLIW
                     HRGTYVCFPMRYGYMLVFAVICMAAARVPDFVGDSRVRRNILYAFLGIWCVQMVALGIS
                     LIQPETHTDETDFVGDATEIGQPLEGKTDVFHKAKLADGAIDNNYPLIAESTSYSNYLH
                     LMTSEQISMNTLLGYSQVWTRLSDTGGTLASDIMLGYRYYVASKAGSWGKDTAADSFWP
                     LAETEKFTLWENAPVGDRAFFITKADYEAYAATEAYTENVFENQNRLSELLFHTVPIDW
                     EKETYLDDQTGAELSYRFHADGKQILYLYGKDLQQAEITVNGKRLYVPDYNDLYNESYP
                     ATGNGGILSIGCFADEDITVDIRQSVGNSGAERAVFFGLLDPQELLEAVDTAGRSVTYE
                     LDRDSCKLTVESAGEEYLMLPINADGGWHCTVNGEERTISRLAGNLMLVPLDAGTNEIT
                     LCYVPRGMKKGAAVTGIALMLLAGWGFLSRLLRRESVLDKIYAGLGYAATGIFAVVYAG
                     FLLVVYVIPVVYTIYLRWI"
     CDS             12542..14026
                     /locus_tag="ctg14_8"
                     /transl_table=11
                     /translation="MEKLQARKKVYLWLLILLSLCALIPLAVLSKYNHQSGDDYGYAYR
                     TFQIWRESHSFWNVIKEAFATSAEFYQKWQGLYASAVLLALEPGIFGDKYYALTGILLL
                     GIIVGSNCAGTVYIFHRKCGCRKLEGFAVGCVMSFLMIEWMPSALQGLYWYNGAMNYVF
                     FHAVLLLLLCVLLSLAGEHPRRRAGRTVIAVLLAVLLAGGNHVTAFMGILLIAGFGIFA
                     AVKKRWQNLICCAITLVAILAGFLFNVTSPGTRIRQSYFSDRPGVAGTIVTAVKNGIAC
                     INSWMGLAVIVTAVLLLPVLLSMVTKIRGQYGFSFRYPLLVFVLSVAWLCAMFCPPIYA
                     MGTPGDVRLTNVVYFSFVWLFVLNEAYLCGWVVTKLEASGAAGLCSRAGELTDSFLITA
                     AVLAVGMIIGCGENMTAWQAYLLIRSGEAQEYSAEADERYAVLCDSAGEDVVLKSYTAK
                     PWMLFLDDITEEKSDWRNEYMRVYFGLNSVVLEQTE"
ORIGIN
        1 acaaaagtcc tacaaattgt cttccgggat gcggacatga cccgcggagt gctccaaact
       61 tggaaagaca cggatcatcg aagatgcaaa catccggctg gttagaaatg ccacattttt
      121 tgaaccaaat ttccctctgt atctccatct gaaatcccac ggtgtgatct tctgataata
      181 ttacttatca cgaaaagggg ctgcacattt gatgcgcagc ccctttctct gtatctgtca
      241 gcctgcagcc tgatccttct gctccggtgc gttctgcttt gccagatttt tgttcgcggt
      301 ggagagcatc agcttgatac ggttgagctg gtttacctcg ctggcacccg gatcgtaatc
      361 gatggccacg atattggaac ccggatagcg gtgacgcagt tccttgatga cgcccttgcc
      421 gaccacatgg ttcggcaggc aggcgaatgg ctgcgtgcag acgatgttcg gtgttccggt
      481 gtggatcagc tctaacatct caccggttaa gaaccagccc tcgccggtct ggttgccctc
      541 ggatacaatg tctcttgcat atctggcaag atcatcgatg tgcgcaggtg cagtaaagtg
      601 cctgctcttt gtgaattcat ctcttgcagc gctgcgcagc cactcaaaga aattgatgcc
      661 cagacggccg atcttcttgg acttctggct catgccgaga ttgtctgctt taaagcccgt
      721 attgtagaag cagtagagca ggaaatcggt cagatccggt acaacggcct ctgcaccctc
      781 ggattcgaga agctccacca gatgattgtt ggcagccgga tggaacttga caagaatctc
      841 gccgacaacg ccgacgcgcg gtttcttgat gtctttgcgc ggaaggttgt caaaatcgcg
      901 gatgatctcg cggcacattt tcttgaactt gccgtgggag agcatctttt tctgggtaat
      961 aaaggcgata acctcttttt tccatttctc gtgcaactcg tccgttgatc cggcaaccgc
     1021 ctcgtaaggg cgcgttgcgt agacgcagcg catgaagata tcgccaaact ccagcgcgta
     1081 gagtccgtgc tggatcagtg gcagtgtcag cttaaagccc gggtttttct ccagaccgct
     1141 cagattgatc gagatgaccg gaacgtccgg atagccggct ttttccagtg cacgccggat
     1201 gaagccgatg taattgctgg cgcggcagcc gccgccggtc tgggagatta agaccgcggt
     1261 gcgcgacata tcataaccgc cggacatcac ggccgccatc agctggccaa ccacgatcag
     1321 ggacgggtag caggcgtcat tgttgacgta ctttaagccg acatccacgc aggtgcggct
     1381 gtccacatcc ggaacaacaa ggttgtaccc ggccgtctgg aacgccggct ccaacagctc
     1441 aaaatggatc ggtgacatct gtgggcagag gatggtgtaa ttcttgcgca tttcctccgt
     1501 gaagacgacg cggttgtaat tcgccggaac gatggtgcgc ttcgtctgct tcttctcacg
     1561 gacacggatc gccgagatca gggaacggat acggatgcgc gccgcaccga ggttgttgac
     1621 ctcatcgatt tttaaacagg tgtagatctt gccggacttt gtcagaatat cattgacagc
     1681 gtctgtcgtg acggcatcca gaccacagcc gaaggaattc agctggatga ggtcgagatc
     1741 gtctcttgtc ttgacatagt tcgccgctgc gtacagtctg gagtgataca tccactgatc
     1801 catgacgatg agtgggcgct ccaccggctg taagtgggag atggaatcct ccgtgagcac
     1861 ggcgatgccg taggaggtaa tcagctccgg aataccgtgg ttgatctcag ggtctatatg
     1921 gtacggacga cctgcgagga cgataccgcg tcttccggtc tcctttaaat actgtaagac
     1981 ttcctcgcct tttttctgca tctccatccg gcagacggca agctccttcc agccttcggc
     2041 aaccgcgtcg cggatctcgg attccggaat cccgaactcc gactggccaa aggtcttaat
     2101 cagctgggag gaaagcgtct cctcgctggc gaaagacata aacggattta agaacttcac
     2161 ctgaccggaa gtgatctcgt ccacgttatt tttgatattt tccgcgtagg aggtaacgat
     2221 cggacagttg tagtgattgt tggaatccgg gaattcgttg cgctcataag gaatacacgg
     2281 gtagaaaata aaatcgacgt tctggtggat cagccatgtc acatgaccgt gtgccagctt
     2341 tgccgggtag cactcggact cgctcgggat ggaatcaatt ccaagctcgt agatcttgcg
     2401 cgtcgactgc ggggagagta ccacggaaaa accgagcttc ttaaagaaag ttgcccagaa
     2461 cgggtagttc tcgtacatat ttaaaacgcg cggaataccg actgtgccgc gtgctgcttc
     2521 ctcggcggaa agcggggtgt agtcaaacag gcgtttgttc ttgtattcgt agaggtttgg
     2581 aatgttgtct ttatttttct ccttgccgag gccgcgctca cagcggttgc cggtgatata
     2641 ctggcggttg ccggaaaagc ggttgattgt gaggagacag tggttggtac atccctgaca
     2701 tcttgccagc tttgtgtcga aggtcagcgc attgatctgt tcgatggaaa gcatggaggt
     2761 ctggtagcct gcctcgtgac gctctctggc gatcagtgcg gcaccgaaag cacccatgat
     2821 gccggcaata tccggacgga cacattcgac acccgcaatt ttctcaaaac tgcgcagtac
     2881 ggcatcgttg taaaacgtac cgccctgtac gacgatattt ttcccgagct ggcttgcatc
     2941 ggaaagcttg attaccttaa ataaagcatt cttgatgaca gagtacgcaa gacccgcaga
     3001 aatatctgca acggatgcgc cctctttctg cgcctgcttt actttggaat tcataaatac
     3061 ggtgcagcgg gttccaagat cgatcggatt tttggcaaaa agagcctcct ttgcaaaatc
     3121 ctgtacagag tagttgaggg attttgcaaa cgtctcgatg aaagaaccgc agccggagga
     3181 acaagcctca ttgagctgta cggaatccac cgtctgattc ttgatcttga tacatttcat
     3241 atcctgaccg ccgatgtcta agatacagtc gacttccggg tcgaagaacg cggctgcata
     3301 gaaatgtgcc accgtctcaa cctcgccgtc atcgagcatc aaagcggctt ttaacagcgc
     3361 ttcaccgtat ccggtggagc aggagtgaac gatctttgcc ttcggtggaa ggagcgtata
     3421 gatctccttg atggaacgga ttgccgtcgc aagcggactt ccgttgttgt tgctgtagaa
     3481 agaatacaaa agggaaccgt cctcgccgac taaggcaatc ttggtcgtgg tggaacctgc
     3541 atcgatgccc agatagcagt tgccctcgta ggtggagaga tctgcggact tgacattgtg
     3601 cccgtcgtgg cgcgcacgga aagcgtcgta ctcttcctgg ctggcaaaca gaggatccat
     3661 acgggcaacc tcaaattcca tcttgatgcc gttcgcgagc cggtcgcgga gagagacgag
     3721 cgtggtcgtc tcacccggct tgtaatttaa agcggaaccg atcgcagcaa acagatggga
     3781 attctccggt gtgatggcgt gttcgtcgtc cagattcaag gtgcggataa aagcagcctt
     3841 gagctcggaa aggaagtgaa gcggacctcc gagaaaggca acatgaccgc ggatcggctt
     3901 accgcaggca agaccgctga tcgtctgatt gaccactgcc tggaaaatgg aggcagagag
     3961 atcctctctg gtagcaccct cgttgattaa cggctggata tcggtcttgg caaagacacc
     4021 gcaacgcgca gcgatcgggt agatggcctt gtaattcttg gcgtattcat tcagacctgt
     4081 cgcatccgtc tggatgaggg atgccatctg gtcgataaaa gaaccggtac cgccggcaca
     4141 gatgccgttc atacgctgct cgacattgcc gccctcaaaa tagatgatct tggcatcctc
     4201 accaccgagc tcgatggcaa catcggtctg cggtgcataa tgctgcaggg cagtggacac
     4261 ggcgatcact tcctggacaa acggaacacc gagatgcttg gcgagtgtca gaccgccgga
     4321 accggtaatc atcggtgcaa cagcaaagtc gccgagtgca tcgtaagctt tctggagaag
     4381 ggaggataag gtctcctgga tattggcaaa atggcgctca taatcagaga agagcagatg
     4441 atcctcctgg tctaaaattg cgaccttgac ggttgtggaa ccgatgtcga ttcccaattt
     4501 atgaagtgta ttgttttcca taattccctc catggctgtt tctcgtaaag taaatacttt
     4561 agcagagtaa aatatgtaaa agatttcttc ttattataaa tagtgccaat ctggcgctaa
     4621 acactctaca ttatacgaca ggatatgtca aaagacaatg tgcattttgc cggaaaagta
     4681 taaacttttt gtaaagaaga atccctctga ttgacaaaga tttccccgac cgatatactg
     4741 aacaacgtaa tgtcattttt ggaaaggtca ggaacagagt gtatgaactg gttaaataaa
     4801 ttagaacgta aattcggcaa ttgggcgatt cccaatctga tcgtgtggct gatcggagct
     4861 tacacgatcg ggtttgtgct ctaccaggtg aatccgtcga tcataggact tttgatgttg
     4921 agtccgtatc acatcctgca cggacagatc tggcgtctga ttacctgggt gtttatgccc
     4981 acagacacga atctggtgta tcttctcatt atggcgcttt tttattatca gcttggaacg
     5041 acactggagc gcacatgggg aaccttccgg tttaacgtct atattttcgg aggtatgctg
     5101 tttaccgtca tcggagcgtt tctgctgtac ggtatcatgt accttttaaa cggcggtgtg
     5161 acgacggaga tgcttctcat cggaacgagt ttcagcacaa gttacatcaa catgtccatc
     5221 ttccttgcgt ttgcatgtat gtatccggat atgcaggttc ttctgatgtt cattatcccg
     5281 attaagatga agtggatggc ggctgtgtac ggcgttctga ttgctttaag cttttttgag
     5341 accggatggg cgggaagaat ggcgattttt atgtcgctcc tcaactttat tattttcttc
     5401 ttctccacca gaaacctcaa gcgctatacg ccgcacgagg tgcacagacg gcagaagttt
     5461 aaggcagaca tgcgaagacc gcagggatat gcgggcggtg cgaagcacaa gtgtgctgtc
     5521 tgcggcagga cggagcttga cgatccgacg ctggaattcc gtttctgctc caagtgcgag
     5581 ggcaattacg aatactgcca ggatcatctg tttacacatc agcatattcg cttgagctag
     5641 aaagtatgaa aaagaaaaaa ggtgatactt cgattccgcg agccggcgga gaagaagtat
     5701 cacctttttg tttcttttag gagtagaatt tttttaacat atccatccgt gcattcatat
     5761 tggaaaaaag tgcgtcgacg atcgtgatgg ctgccatgga ttccaccacg acaacggcgc
     5821 gcggaacgat gatcggatcg tggcgtccct tgatgttgac cgagatctcc tccccggact
     5881 gattgacagt gcgctgtgtg gctgcgatgg aaggggtcgg cttgatggca gcccggagga
     5941 tgatgtcgct tccgtcgctc atgccgccta agataccgcc ggcatggttg gttgctttgg
     6001 caatcctgcc gtcctcaccg aggacaaagg catcgttgtt gttcttgccg gtcgcttttg
     6061 ctacgtcaaa tccgtccccg atctcaaaac ctttgacggc accgatggac atgacagcct
     6121 tggcaaggtt cgcattaagc ttttcgaaga ccggatctcc gatgccggcg ggcatcccct
     6181 ttatgataca ctccacaatg ccgccggagg aattcagttc cgccatgcag gcatccagat
     6241 agttttcggc gttctcggct gcctcggcgt ccggcatata gagcggattc tttgtgatct
     6301 cggaaaaatc aaagcgcccg gaagatacgg cgatcgggcc gatggacttt gtgtaggtca
     6361 taaaggtaat gccgagttcg tttagaatct tgacggcgac ggcgccggcg gcgacgcgtc
     6421 cgatggtttc ccgcccggag gagcgtccgc ccccacggta gtcgcggaag ccgtatttcc
     6481 ggtcgaacgt gtaatcggcg tgaccgggac ggtagtagga ggcgatctcg ctgtagtctt
     6541 tggactgctg gttgcggttg aagacgacaa gcgagatcgg tgtgccggtc gtctttcctt
     6601 caaacacgcc ggagagaatc tctacggcgt catcctcctt gcgcggggtc gcatatctgg
     6661 actgaccggg cttgcgccgg tcgagaaact tctggatatc tgcttcacag agagaaagtc
     6721 ccgccggaca cccgtcgatg acgacgccga caccctttcc gtgagattcc ccccaggttg
     6781 tgattttaaa aagagttccc aatgtagacc ctgccatgtg attccctcct gcttacataa
     6841 tgatctttct cgattataaa agatttgact ttgcgccgca acagaaatat gttatgattt
     6901 gacggagcag aagtaccagc aggcgaggag aagaatattt catgatagag aaataccttg
     6961 tgaaaaagat aacagagccg gtggactgga aggtgaccgt gccgggatca aagagcatga
     7021 cgaaccgcgc gcttctttta gcagcgctgt ccgcagggac ggtgcgcgtg gaaggcgttc
     7081 tgttttccga tgattccaga cattttctgg cgtgtcttgt ggcgctcggc tttacagtgg
     7141 agatagagga agaaaaaaag tgcgtgaccg tgacgggctg cggcggcagg attcccagcg
     7201 gggaggcggc aatcgacgtc ggaagcgctg ggacagcggc gcgtttcctt gcggcgatgc
     7261 tcggattttc ggacgggtgt tatgagatcc gctgttcagc gcagatgaag cggcggccga
     7321 tggcggagct gttcgaactg ctttccggtg cgggggcgaa gattaccttc ctcgaggagg
     7381 aagggcatct tccggtgcgc atcacagggt gcagatctgc ccgggcagat gagacggcag
     7441 gggagacgcc gcggagactc tcccttgaca ttacgaagag cacacagttt ttaagcgcgc
     7501 tgctattgat tgcgccgatg gttccggagg ggatgaagat ccatattacc agtgagaaga
     7561 cggacggctc atacatccgc atcacgcgga agatgatgca ggaattcggc gtgagtgtcg
     7621 cttttgacgg aagagattac gaggtgccgc acagaagttc ctaccggaaa gaggcttata
     7681 cggtggaacc ggatatgtcg gctgcctgct atttttatgc ggctgcggct gtgaccggcg
     7741 gacgggcgct tgtgcggcat gtgcatatgg acaacacaca gggagatctg cgtttcctgg
     7801 aagtgttgga gcacatggga tgtaccgcgg acgatacgcc ggagggcgtc ctggtaacgg
     7861 gaccggcgga cggtgcgttg cggggcatca cagttaatat gaacgatttc tccgatcagg
     7921 cgctgaccct ggcggcgatc gcgccgtttg ccgacgcgcc ggtgcgcata gagggaatcg
     7981 gacatatccg cgggcaggaa tgcgaccgga ttcacgcgat acagacgaac ctgacagcgc
     8041 ttggcatccg gtgtgaggag gaagagacgg ctgtcacgat ctatcccggc agcccccacg
     8101 gcggaagcgt ggagacatac gacgatcacc gcgtggcgat ggcattttcc ctgatcgggc
     8161 ttagaaccga cggtattgtg attgagaacc cggcatgctg ccgcaagacg tttgaaaatt
     8221 actttaccgt gttaagcgaa ctgaccggga aaacggcaga agattgacgg ggcaccggtt
     8281 ttgcatgagc cagggaagca gaagtgcaga acgacagtaa gtaaatagag aagaacgaca
     8341 ggtaataaac gacaggtaat aaaaggagac gaaaaaacag atgtatgaat tattaaagca
     8401 ggaaggacgc gcgaaacgag gcgttttcca tacggtgcat ggagatatcc agacgccggt
     8461 gtttatgaat gtgggtacag tggctgccat caagggagct gtctccacgg aagatttaga
     8521 gcagatcaaa tgtcaggtgg agctgtcaaa cacctatcat ctgcatgtgc gcaccggaga
     8581 caagctgatc aaggaagtgg gaggactgca caagtttatg tcgtggaatc gtccgattct
     8641 tacggattcc ggcggatttc aggtgttctc cctggcaggc ctgcgcaaga tcaaggagga
     8701 gggcgtctat ttccactcgc atattgacgg ggcaaagatt ttcatgggac cggaggagag
     8761 catgcagatc cagtccaatc tcggttccac gatcgctatg gcgttcgatg aatgcccgcc
     8821 ggcgcttgcc gagcggaaat atgtggagga ttccgtggca cggacgacac gctggctgga
     8881 gcgctgcaag aacgagatgc agcgcctcaa tgggctggag gataccgtga accgtcacca
     8941 gatgctgttc ggcatcaacc agggagccat ctacacggac atccggatcg accatgcaaa
     9001 gcggatttcc gagctggatc tggacggcta tgcggtcggc ggacttgcgg tcggcgagac
     9061 acacgaggag atgtaccatg tgctggatga gaccgtgcct tatcttccgg tgaacaagcc
     9121 gacctatctc atgggagtcg gaacgccggc caatattctg gagggagtgg agcgcggcat
     9181 tgacttcttc gactgtgttt atccgtcccg caacggccga catggccatg tatacacgaa
     9241 ccagggcaag atcaacctgt tcaaccagaa gtacgagaag gatatgcgcc cgatcgaaga
     9301 gggctgcggc tgcccgacct gccgccgcta cagcagagcc tatatccgcc atctgctcaa
     9361 ggcaaaagag atgcttggca tgcgcttatg tgttctgcac aatctgtact tctacaacac
     9421 gatgatggaa gagattcggg atgcgctgga tgccggaaac tttgcctcct acaaggaaga
     9481 aaagctatac agcatgggac agatcaaccg ggaaaaggaa atggcaaagt aaaagggaaa
     9541 aggcttgcca aacggcgagg ttttgtgtac aatactttct aatggggtca gacgacttcg
     9601 gacaagttta tgattttagg aggatatcag atgttttcaa tcttagcaac agagagcgcg
     9661 tcatccgcag gctggatcag catggtggta tggctggtta ttttatttgc atttatgtat
     9721 ttcttcatgg tgcgtccgca gaagaaagag cagcagaaga agaactccat gcttgcagag
     9781 ctggcagttg gagatactat cttaacgaca agcggtttct acggaaccgt gatcgacatc
     9841 gcagacgata cggtgatcgt ggaattcgga agcaacaaga actgccgcat cccgatgcag
     9901 aaggcagcga tctccgcagt tgagaaaccg gaagatgtaa ctgaataaga agattttaaa
     9961 gagggatagt atataaaatg tattatccct tttctttttg agagagtatt tgggagagcg
    10021 aggagagatt ggtcggatga aaagtaaaaa gaatacgctt gtttcacgtg ccgccgtcgg
    10081 ctgcgtgaca actgccattt ttctgctgtt gtgcatcata aagggcatct atccgtttgg
    10141 aattgccacg cttgacactg tggattttca gtcccagtgg attccggcat attaccatgt
    10201 atgggatgtg ctgcacggag acggcagcgc cttttttgac tggagagtcg gcggcgggaa
    10261 taattttgcg ggagtgagcg cgcagttttc tctgctcagc ccgtttaacc tgttcttcct
    10321 ctttgtgaaa agaagctgga ttgaaaaatc catgatcgtg tttcttttaa tcaagctgct
    10381 agtcatgggc tatggcatgc gctggttttt aaaagagcag atccttaagg aagagcgtta
    10441 cggaatctac attctggcgg gaagcgtggg gtatgccgta aacggctata cgcttttgta
    10501 ctatggcatg ggctggctgg atgtggcagc gatcctgccg ctattgtgtt atttcttctg
    10561 caggatggcg gagcgggaag gggactggcg tctcgggaaa aatacgctcg gctatatcgt
    10621 ctgcctgacg ctggtattcc tcatcaatat tccgcaggcg tacatgatgt gttttttcct
    10681 gatcgtgttt gcggggggat attttttcct gaaacgacag gaccagccgc taaaaaagaa
    10741 cggcatttta aaattcgggc tgacttcttt actgtcgctt ggaattgcgg cggtaatatt
    10801 tctgccggca gcgagggcaa tgcttggttc ctaccggctg tcgggcgagg agtaccgggg
    10861 aatctccggc tattttctgc tgcttcggca ggacggaatg gacgcggtgt ggaaatgggt
    10921 gattcttggc agcgtggcgg ttccgctgct gttcttcgtt atttctggca gacggaagcg
    10981 ggagcacatc tggcagtggt atctggtggc ggcgatggtg ctgccggttt tcttcgaggc
    11041 ggtcaatctc atctggcacc gcgggacgta tgtgtgcttc ccgatgcgat atggttatat
    11101 gctggtgttt gccgtgattt gtatggcagc ggcgcgcgtg ccggattttg tgggagatag
    11161 ccgcgtgcgg cggaacattt tatatgcgtt cctgggaatc tggtgcgtgc agatggtggc
    11221 gcttggcatt tctttgatac agccggaaac gcacacggac gagacggatt ttgttgggga
    11281 tgccacggaa atcggtcagc cgcttgaggg aaaaaccgat gttttccaca aggcaaagct
    11341 ggcggacgga gcgattgaca acaactatcc gctgatcgca gagagcacct cctactccaa
    11401 ttatctgcat ctgatgacgt cggagcagat cagtatgaac acactgctcg ggtattctca
    11461 ggtgtggacc agattaagtg acacgggcgg aacgctcgcg tccgacatca tgctggggta
    11521 ccgttattat gtggcgtcta aggcgggatc gtggggaaaa gacacggcgg cggattcctt
    11581 ttggccgctt gctgagaccg aaaagtttac gctgtgggaa aatgcgcccg tcggggacag
    11641 ggcatttttt atcacaaaag cggactatga agcgtatgca gccacggaag cgtacacgga
    11701 aaatgtgttt gagaaccaga accggctgtc ggagctgctt tttcacacag ttcccattga
    11761 ctgggaaaaa gagacctatc tggatgatca gaccggagcg gaattatcgt accggtttca
    11821 cgcagacgga aagcagatcc tatatctcta tggaaaggat ctgcagcagg cagaaattac
    11881 ggtaaacgga aagaggctct acgtcccgga ttacaatgat ctgtacaatg agagctatcc
    11941 tgcaaccggc aatgggggaa ttctctccat cgggtgtttt gcggacgagg acatcacggt
    12001 agatatccgc cagtccgtcg ggaacagcgg cgcagagaga gcggtgttct tcggactcct
    12061 cgatccgcag gaactgctgg aggcggtgga tacggcggga aggtcggtta catatgaact
    12121 ggatcgggat tcctgtaagc tcaccgtcga atcggcggga gaggagtatc tgatgcttcc
    12181 aatcaatgcg gatggcggat ggcattgtac ggtaaacgga gaggagcgga ccataagccg
    12241 gctcgcgggc aatctgatgc ttgtgccgct tgatgcggga acgaacgaga tcacgctttg
    12301 ttatgtgccg cggggaatga aaaagggcgc ggcggtgacg ggtatagccc tgatgcttct
    12361 ggcaggctgg ggctttctct cgcgtctgct tcggagagaa agcgtcctgg ataaaatcta
    12421 cgccggactt ggctatgccg ccacaggtat ttttgcggtg gtctatgccg gatttctgct
    12481 ggttgtctat gtgattccgg tggtgtatac gatatattta agatggatct gaggtaacag
    12541 aatggaaaaa ttacaagcga gaaaaaaagt atatttgtgg ctgctgattc tattgagtct
    12601 ttgcgcgctg atcccgttag ccgtactctc gaagtacaat catcagtcgg gggatgacta
    12661 cggttatgcc taccgtacct tccagatctg gcgggagtca cattctttct ggaatgtcat
    12721 aaaagaagcg tttgccacat ccgcggagtt ctatcagaag tggcaggggc tatatgcatc
    12781 ggcggtgctg ctggcgctgg aaccgggaat tttcggcgac aaatattatg cgctgaccgg
    12841 aattttgctg ctcggaatca ttgtggggtc aaactgcgca ggtacggttt atatctttca
    12901 ccgtaaatgc gggtgccgga aactggaggg atttgctgtc ggctgcgtca tgtcgtttct
    12961 tatgatcgaa tggatgccct ccgccctgca gggattgtac tggtataacg gggcgatgaa
    13021 ttatgtattc ttccatgcgg tactgttatt gctgttatgc gtgctgctta gccttgccgg
    13081 ggagcatccg cggagaaggg caggcaggac ggtgattgcg gtattgcttg cggtgctgct
    13141 tgccggcggg aatcatgtga ccgcatttat gggaatattg ctgattgccg gatttggaat
    13201 atttgctgcg gtaaaaaagc ggtggcagaa cctgatctgc tgcgccataa cgcttgtggc
    13261 tatacttgct ggattccttt ttaacgtgac atcgccgggc accagaatcc ggcagtcgta
    13321 tttttccgac agacccggcg tggcgggaac gattgtcacg gccgtaaaaa acggaattgc
    13381 atgcatcaac agctggatgg gactggcggt cattgtcacg gcggtcctgc tgctccctgt
    13441 gcttctttcc atggtaacga agatacgcgg gcagtacgga ttttcgttcc gctatccgct
    13501 gcttgtcttt gtgctgtcgg ttgcctggct gtgcgcaatg ttctgtccgc ccatctacgc
    13561 gatgggaacg ccgggggacg tccggctgac caacgtggta tatttttcct tcgtctggct
    13621 gtttgtgtta aatgaagcct atctgtgcgg gtgggtggtc acaaaactgg aggcgtccgg
    13681 ggcggcagga ctgtgtagca gggcaggaga acttacggac agctttctga tcacggctgc
    13741 tgtccttgcg gtgggaatga taatcggatg cggggaaaat atgaccgcat ggcaggcata
    13801 cctgctgatc cgcagcggcg aggcacagga atattcggcg gaggctgatg agcgctacgc
    13861 cgttttgtgt gattctgcgg gggaagacgt ggtgttaaag tcgtataccg caaagccgtg
    13921 gatgcttttc cttgacgata ttacagagga gaaaagcgac tggagaaatg aatatatgcg
    13981 cgtctatttt ggactgaaca gcgttgtgtt agagcagacg gaatgagacg gcagaaggga
    14041 gcagcggaca caaaaggcag gctgctcctt tttcataaga cccggttata gggagtatga
    14101 aaaagaaaaa tggattcaga ggttgcattg tttcccgaga tacattatta tagaatttat
    14161 atactgtctg ttagtaatgt actaaagtca atacaagacg gattcctgca tggcaggaag
    14221 aaaagaggga ttagagagat ggaatataag gtaggcgtga tttccggcga cgggatcgga
    14281 ccggagatcg taacagaggc aaagaaagtt ctggatcaga ttggaaagat ctacggacat
    14341 gtgttccgct atgaagagat tctgatggga ggctgctcca ttgacgcgac gggtgagccg
    14401 ctcacggatg cggcgatcgc ttccgcgaag gcttccgatg cggtgctgat gggttcgatc
    14461 ggcggcaaca catcgacttc gccgtggtat cagctgccgc cggagaagag accggaggcg
    14521 g
//
