LOCUS       c00081_gnlPro..        15032 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KGNGFJNL_113.
ACCESSION   c00081_gnlPro..
VERSION     c00081_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:32:17
            Original ID  :: gnl|Prokka|KGNGFJNL_113
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15032
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15032
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1592:5032]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1593..5032
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15032
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15032
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(380..1333)
                     /locus_tag="ctg81_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPASGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1593..2267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_2"
                     /sec_met_domain="SucD_FumR (E-value: 8e-67, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2306..4249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4277..5032
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_4"
                     /sec_met_domain="Fer2_3 (E-value: 8e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.4e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5223..5381
                     /locus_tag="ctg81_5"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5354..6385)
                     /locus_tag="ctg81_6"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLNILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6790..8025
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_7"
                     /sec_met_domain="Peptidase_U32 (E-value: 1e-68, bitscore:
                     223.7, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNNFTTDDLRK
                     IVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAMNYANSIGQ
                     EVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITGPKGELIRI
                     EMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIELDIENQYIM
                     SPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNGTFDEKKVA
                     AWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDKIGVAEFEM
                     ESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEKIRPSDRLY
                     KMEKVQLEKVFE"
     CDS             8025..8432
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_8"
                     /sec_met_domain="HBT (E-value: 1.6e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2.4e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8429..9544
                     /locus_tag="ctg81_9"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             9662..9811
                     /locus_tag="ctg81_10"
                     /transl_table=11
                     /translation="MKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIHSSRAFVKHFV
                     ANTC"
     CDS             complement(9872..10768)
                     /locus_tag="ctg81_11"
                     /transl_table=11
                     /translation="MKMLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYF
                     RYAPDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDET
                     IDRTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDV
                     PLEVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPW
                     KQVMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPD
                     VIETDYPYLFQGLDLTK"
     CDS             11461..11823
                     /locus_tag="ctg81_12"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             11844..13016
                     /locus_tag="ctg81_13"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDKILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPV
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNPVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKIWYRGTG"
     CDS             12964..13581
                     /locus_tag="ctg81_14"
                     /transl_table=11
                     /translation="MSDTRNRPLKYGIEGRVSCSFVVGKDGAISEAEVIRGVSPELNEE
                     ALRVINSMPVWSPGKQRGKVVNVKYTVPVTFRLSGGKKKTSSRIVQRQIKEVDTSGRVF
                     TVVQQMPEFPSGQASLLKYLATRIKYPAIAQENGIQGRVSCSFVVDTDGSLKNIEVIRG
                     IDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFRLQ"
ORIGIN
        1 acccttgcga cgagtcaatg acttctcttt tttcatcttt gttgactttt atgaagtcaa
       61 cctatttcag gacgagacaa tcgctcatct atctgtttta aatgaataaa ctccaagcat
      121 tttaaggtaa aagtagggag acaattttat caacaccccc atgtatccgc ccccgacacc
      181 cggatcttac gctcttatag atccgggtgt cgggggcgga tacatggggg tgttgggtaa
      241 gttttattac gtgtttttca ttgatttgta gctgtattta cataaaagag ccttgtcttt
      301 gatgatatag gagaacaagc cctttttcct tttcttgttt accttgccct gcaaattgtc
      361 agtttgtttt agtagaaatt caatcacgtt cgaaatcgga cagcacttct gccgtagtag
      421 cgttgatgtt cttgtccaat acataaatgc ggtaagacag gctcagttct ttaccgggtt
      481 ccaaggtgaa tgccttctgc ttggtcggtg agaaattcca catgacgtca ccggcaggct
      541 tgttgacagt tttgtcccat acgcgtaaag gctcaggata gttcaggttg gaaggggagg
      601 caacgattag gatacaggcc ttttcgtttc cggctttccc ttggtagtag caccaacggg
      661 ctctcgaacc gtcagcttcg tcgcgggaaa ggccttccga ggtgagcatt tcggctgtct
      721 gatcgttcca gtcttcgcgc gtacggatgc atatgccgcc ataacggtaa gcttccatgg
      781 tgatcgggct ggggctggcg aggcggatag tggtatgata gtcgatgtaa taacctggta
      841 aggatgttgt cccgatgttg atctccaggc gttcgttcat tgctactttt tctgcgggag
      901 aatcggggta gaccacatgg tccagtgtcg caacaaaacc gttgtcggat acgtgttcga
      961 agttgcggaa gcgaactgtt ccttgttttt tgtggagatt ccagaagtcg atctcgtttc
     1021 cttcgaacgt ggttttcgtc caggcatacc acaaaccgaa atgatggtaa tggtcggcgg
     1081 gagaacaatt ggtcatcact tcgcctccca atgtcttcaa aggatggatg aaaccgctgc
     1141 gtttatagac cgagtcaacg ccagaggctg ggtaaactgt ggtatagttg taagagaaca
     1201 acagtttatc tcctatctta tagtctaagg ttttccccgt gtcgacgacg gaacaggatg
     1261 tttcggaagg ctgacaagag cctaagaaca gagaaatcaa aaaaacacca atagaaaaaa
     1321 tagcagtttt cataatatga caattaaata ataatcagtt atccggcaag accttgcctg
     1381 tatcggctac aaaaaaacga aattttttcg tttcgcacaa tccgtttgtg atatctgatg
     1441 caaataaaac cagccagcaa gcagcgttct aattgatgaa atatttcttt aatcgtttgc
     1501 gtgatatggg gatttagcat acctttgcac gataataacc atagattgga ggaaatttct
     1561 aaatacaatt aaataactta aattattatc ttatgtggtt acttaattct tctatcggga
     1621 agaagctgat aatgagtata tcaggtcttt ttctcattct gttcttggtg ttccacttat
     1681 gtatgaacat tgcggcagta ttttctggtg aagcgtataa cgtgatttgc ggtttgctgg
     1741 gttctaactg gtatgctttg ctcggtacat tggtgttggc tgcaggtgta gtcgtgcact
     1801 tcgtgtatgc tattatcttg actctgcaga atcgtaaggc tcgcggtaac gaccgttatg
     1861 ccatcaacgc tcgtccgaaa ggtgttgaat gggcttctca gaacatgttt gttttgggtg
     1921 tgatcgttat cctgttcatg gttctgcact ttactcagtt ctggtacaac atgatgtttg
     1981 ccgaactggc aggtattcat ggtgacattc atccgcagga tggtgcagcg tttatcaatt
     2041 tctacttcca gggcaatgtc gtgaatacgg tgttgtatct gatctggttc gttgctctgt
     2101 ggtttcacct gactcacggt ttctggtctg cgattcacac aattggctgg aacaataccg
     2161 tttggttaag ccgttgggaa tgtatctcta aatgggttgc cactattatt tgtggcttat
     2221 tcgctgttat cacagttatc ttctacctga acggtgtagg tgcttaattt cggatattat
     2281 tttttcaatt tgaaaataaa acattatgac tcaaatagat tctaaaattc ctcaaggccc
     2341 gttggctgag aagtggacaa attataaaaa tcaccagaaa ttggtgaatc ccgcaaacaa
     2401 acgtcgtttg gacataattg tagtaggtac tggtctggcg ggtgcttctg ctgctgcctc
     2461 tctggctgaa atgggattca atgtattgaa tttctgtatt caggactctc cccgtcgtgc
     2521 acactctatc gctgcacagg gcggtatcaa tgcggcaaag aattatcaga atgatggtga
     2581 ctcggtttat cgtctgttct acgatacaat caaaggtggt gactaccgtg cccgcgaagc
     2641 aaacgtctat cgtctggctg aagtgtcaaa ctctattatc gaccagtgcg tagcacaggg
     2701 tgtaccattc gctcgcgaat atggtggtct gttggataac cgttcattcg gtggtgctca
     2761 ggtatcccgt acgttctatg cccgtggtca gaccggacag cagctgctgt tgggtgctta
     2821 ctctgcattg agccgtcaga ttggtttggg aaaggtgaag atgtacacac gccatgaaat
     2881 gctggatgtt gtgaaggttg acggacgtgc tcgcggtatt attgcccgta atttgattac
     2941 cggtaagatc gaacgttttg ccgctcacgc agtcgttgtt gcgacaggtg gttatgtaaa
     3001 tacattcttc ttgtctacta acgcgatggc gtctaacggt tctgctgcat ggcagtgcta
     3061 caagaaaggg gcttactttg ctaatccttg tatggtgcag atccacccga cttgtgtgcc
     3121 ggtgaaaggt gacttccagt ctaaactgac tttgatgtct gaatcactgc gtaacgatgg
     3181 tcgcatctgg gttccgaaga agctggaaga tgcgaaggca ttgcaggccg gaacaaaaaa
     3241 gggaaaggat attcctgaag cagatcgcga ctactatctg gaacgtcgtt atccggcatt
     3301 cggtaacttg gttcctcgtg atgtggcttc acgtgccgct aaagaacgtt gtgatgccgg
     3361 tttcggtgta aatagcacgg gcttggctgt attcctggat ttctccgacg ctatcaaccg
     3421 tctgggtaag gaagtggtta aacagaaata tggtaacctg ttcgatatgt acgaagagat
     3481 cacgaacgat gatccgtacg aaactccgat gatgatttat cctgcattgc actactcaat
     3541 gggtggtttg tgggtagact atgaattgat gacttctatt ccggggctgt tcgcaattgg
     3601 tgaagccaac ttctctgacc atggcgctaa ccgtctgggt gcttctgctt tgatgcaggg
     3661 attggctgat ggttactttg tattgcctta cacgatccag aactatctgt ctgaccagat
     3721 ccaggttccg cgctttagca ctgacctgcc tgaatttgtg gaagcagaaa aggctattaa
     3781 cgcccgtatc gcgaagttga tgaacgtgaa gggtaaagaa actgtcgatt ctatccaccg
     3841 taagctggga catatcatgt gggaacacgt cggtatggca cgcgacgcgg aaggcttgaa
     3901 agaagctatc caaatgttga aagacctgaa gaaggaattc tggagcaatg tattcattcc
     3961 gggtgaagcg aacagcttga acgtggaatt ggacaaggca ttgcgtttgg ctgactttat
     4021 cgaaatcggt gcattgatgg cacacgatgc gttagaccgc gcagaatctt gtggtggcca
     4081 cttccgtacg gaacatcaga ccgaagaagg cgaagctatg cgtcatgacg ataagttcat
     4141 gtacgtctct tgttgggaat accagggtga agacaaagac ccggttatgc tgaaggaaga
     4201 tttgaactat cagttcgttg ttcctcaaac acgtaactac aagaagtaat aatcatcaat
     4261 cacaaaaatt agaatcatgg ataaagatat aaaggtaaca cttaaagttt ggcgtcagaa
     4321 aggtccgaaa gataaaggac agtttgagac ttaccaaatc gacaaaatca atcagagtgt
     4381 ttctttcttg gaaatgttag acattttgaa tgaacgtttg gttagcgaag gtaaagaacc
     4441 tatcgtattc gaccacgact gccgtgaagg tatctgcggt atgtgttcat tgtatgtaaa
     4501 cggacatccg cacggaccgg caacaggtgc aacaacctgt cagctctata tgcgccgttt
     4561 caatgatggt gagacgatta cgatcgagcc gtggcgttct gccggtttcc cggtaatccg
     4621 cgacttgatg gtagaccgtt atgcttatga taagattatc caggcaggtg gtttcgtttc
     4681 tgtaaacaca ggtggggttc ctgatgctaa tgcaattcct atttctaagg ctgatgcgga
     4741 tttggctatg gatgctgctg cttgtatcgg ctgcggtgct tgtgctgctg cttgtaagaa
     4801 cggttcagct atgctgttcg tctctgcaaa ggttagccag ctggctcttt tgcctcaggg
     4861 taaggtggaa gctgctcgtc gtgcaaaagc aatggttgct aagatggatg aactgggctt
     4921 tggtaactgt acgaacactc gcgcttgcga aatggaatgt ccgaagaaca tctccgttag
     4981 caacatcgct cgcttgaacc gcgagttcat ctctgctaag ttacaagact aatacattat
     5041 atatatgtat atggaaaagc ccgtcgtcaa tggcaacggg ctttctttat gttcgttcaa
     5101 acccacaaaa aagccgcact ccctataata aaagtggatg cggctttttt gttgctttcc
     5161 agtgaaacag tctctcgatt ccctctctgc aaagactttg ttaaccttag atctaaaata
     5221 ctatgaaaaa aactcactgc aaatataaag tatatttact gaatacgcaa gagtttgtaa
     5281 ttacatttta ttgcaaattt gctacttttt gttttaaaat tgacactgtg tgcggattca
     5341 cactgttatt atatcaacaa tcgatcgatt ctgacacttg agagtcgctt tgaaatccgt
     5401 atcctgtatg aaatttgtcg gggatggaat ccagaatgtc gaataatgct tccactgttt
     5461 ccgcacgtag catggcgacg cgtgtctgct tgaagtctgc aataccttta aacagcggag
     5521 ttgcagccaa atggcggcga atgtggagaa ttccccggcg ctcatccaaa cgttccacgc
     5581 tttgttccac ctgctttttc agtatgttca gataccatga aaaagattcg gcaggcaatg
     5641 tctcgcctgt atccagataa tgcctcactt ctctgaaaat ccaggggcgg cctatgctgc
     5701 cccggccaat cataacggca tccacgccat attgttcgaa acgttgtttg cagatttcgg
     5761 cggaagtcac atcgccattg ccgatgatgg gaatttgtat gcggggattg ttttttactt
     5821 caccgatcag tgtccagtct gcctctcctg tatacatctg tgcccgggta cgtccgtgga
     5881 tggaaagggc tgcgataccg caatcctgta gctgttcggc caagtctacg atgatccggt
     5941 tgtcggcatc ccagcccaag cgggttttta cggtgacagg gatgttcacc gctttgacga
     6001 cttcacgggt gatgtccagc atcagtggaa tattgcgcag catgccggcg cctgctcctt
     6061 tgcctgccac tcgtttgaca gggcaaccga aattgatatc gagaatgtcc ggatgagcgg
     6121 cttcgcaaat ttgcgcggct tcgaccattg tcggaacatc acggccatat atttgtatgg
     6181 cgaccggacg ttcttcatcc gccacattca gcttttgctg tgttttattt acactgcgga
     6241 tcagggcgtc tgctgaaacg aattcggtat aaaccatatc ggcaccaaaa cgtttgcaca
     6301 tcaaccggaa agaaatatct gtaacgtctt ccatcggagc taagaagacg gggcgttcgc
     6361 ctaaatctat tgtacctatt ttcatattta tattatcaat gacggggaca aaggtactga
     6421 tttcctgcta aaaacaggga taaaaggata tctactaaaa agtgtagtaa ttgatcaata
     6481 gaaagtacaa atgtcatact gtcaatgata tagataaaat gataagctga aatcatgata
     6541 gttgcatgat agtagtatga tagttaaaaa tagaaactat catgtcttaa ggtattgaat
     6601 aacagattct aaaggacaac aatgacagta tgatggttgt tttgcaaatc tttatagaaa
     6661 atggtatttg atcacgattt tgatgctctg agaaacggat acccatgcaa ttcttctcgg
     6721 atattattcc tacctttgcg aacgaaccag taaatgtata agaacttgaa cgagaaagat
     6781 tttgaaataa tggcgcctgt cggttcgtac gaatcactga tggcggctat ccaaggggga
     6841 gccgattcta tctatttcgg tatcgaagga ttgaatatgc gttcgcgctc ttccaataac
     6901 tttacgacag acgatttgcg caagatcgtt gcgctttgtc gtgagcacgg tattaagagc
     6961 tatttgaccg tcaatacggt tatttatggg gaagacctgc ctctgatgcg cgagattatc
     7021 gatgcggcga aggaggcgga agtttcagcg atcattgcgg ccgatgtggc agctatgaac
     7081 tatgccaaca gcatcggaca ggaggtgcat ctttccacac agctcaacat ttccaatgcg
     7141 gaagcactga aattctatgc ccgttttgcc gatgttgtcg tcttggcgcg tgagctgaat
     7201 ttgaaacagg tgcatgaaat ctatcggcag atcgtcgacc agcagattac gggaccgaaa
     7261 ggagaactga tccgtatcga aatgtttgcc cacggagctc tctgtatggc cgtttccggt
     7321 aaatgttacc tgagcctgca cgaaatgaac gcttccgcca accggggagc ttgcatgcag
     7381 atttgtcggc gtgcttattc ggtaaaagat aaagacagca atatcgaact ggatatcgaa
     7441 aaccagtata ttatgtcgcc taaagacctt aagacaattc atttcatgaa taagatgatg
     7501 gatgcaggtg tacgggtatt caagatcgaa ggacgtgccc gcggtcccga atatgtccgc
     7561 ctggtgaccg aatgctataa ggaagctgtg cgtgcttatt gcaatggcac gttcgatgaa
     7621 aagaaagttg ccgcttggga cgaacgcctg cgcagtgtgt tcaaccgagg attctgggac
     7681 ggctattatt tggggcaacg gttgggtgag tggagtagca aatatggctc cggcgcgact
     7741 aagaagaaag tgtatgttgc caaaggaatc aaatatttcg acaagatcgg cgtggcggag
     7801 ttcgaaatgg aatccggtaa cctgaaagtg ggtgatgaga tcctgattac cggaccgaca
     7861 acgggtgcgg ttatgcagac gatagaagaa atccgtgtgg acttgaagcc ggtggacgag
     7921 accgttaaag gtgaacggtt ctctctcaag gtgaacgaga agattcggcc gtctgaccga
     7981 ttgtataaaa tggaaaaggt tcaacttgaa aaggtatttg aataatgaaa gagtatattt
     8041 ttaaactgac agacaaggtc cgtgactacg aatgcgacct gcaaggagtg gtcaacaact
     8101 ccaattatca gcattatatg gaacatactc ggcatgaatt cttggagtcg cttggcgaga
     8161 acttcggaaa gatgcacgaa aaaggggttg acggatttgt atcgcgggta gaaatccagt
     8221 ataagacctc gctcaagagc ggcgacagct atatctcttg cctcaatgtc tataaaaaag
     8281 gagtcaagct cgtattcgag caggatatat atagggcttc tgacaatgca ttggcgacga
     8341 aaggaatcgt cgagtcggtt atcgttgaga acggaaagtt gacacgcggt gaatatttcg
     8401 acgaaatgct aaaaagaata gaacatacat gactgacaaa cggatttacc aaatcggcct
     8461 tactatgata aacggcgtgg gagatatcct ggcgcgtcat ctcctgcagg ctttgggaga
     8521 agcagaggct gtgtttactg aaaagcaaca gttgttagga aggatccctg gtatcggcag
     8581 caatattgct gccgaaatca aacgcccgga aatcttgcaa cgggcggaaa aagagttggc
     8641 ttttatcgag aaaaacaata tttcctgtta ttatctgact gatacagatt atccggtgcg
     8701 cttgagagaa tgtccggatg cccctatact tttctatttt aagggaaata ctaaccttga
     8761 tgcgacccgt atcatcagta ttgtgggtac tcgcaacgcg accgaatatg gtcgggagct
     8821 taccgaatcc cttataaaag acttggcaaa agtgatcccg gacttgttgg tcgtgagtgg
     8881 attggcttac ggcatcgata tctgtgccca ccggaacgct ttgtacaacc gacttccgac
     8941 tgttgctgtg ctggcgcatg gcttggatcg tatctatcct tcctgccatc ggaatacggc
     9001 tgtcgaaatg ctggaatcgg gcggtctgtt gaccgatttt cccagcggta cagaaccaga
     9061 ccgtccaaat ttcctccgga ggaaccggat tgtcgccgga atctcggatt gtacgatcgt
     9121 ggttgaatcg gcagaaaaag gaggctcttt ggtaactgcc gatattgcat tctcttatgg
     9181 ccgggatgtc tatagctttc cagggcgcat cggtgacagc cattccaaag gatgcaacaa
     9241 tttgatccga caaaataaag ccggcctgat cacttctgcg gacgatctgc tctccgctct
     9301 ttgttgggat atccaagctg gggctacttc cgttcaaacg gagttgtttt tcgccgaggc
     9361 ggaaacattc acctcggaac aaaatccggt tttagccatt atgcgaacgc ggaatgagat
     9421 ccatatcaac gagcttgcct cagtgttgga gataccggta catcaactct ctatgctatt
     9481 gttcgaactg gaaataaacg ggaaggtaaa agcgttgccg ggaaatctct ataagctgtc
     9541 ctgaccggct ttttcgtata cgatttgtat gtgggagaag aaacggaacc tctataaaca
     9601 attaaaggct gtctcacgac aacccctaac caactttgtt aaccttaaat ctaatactat
     9661 tatgaaaann nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnng atacactcgt caagagcgtt
     9781 tgtcaagcat tttgtcgcta atacttgtta atcagatgag cataaatagc aaaaagattt
     9841 taatcggcta taaagagtcc tttaaactgc gttattttgt taaatcgagt ccttgaaaca
     9901 ggtacggata gtccgtttcg atcacgtcgg gacgagtgct gatctctgac cggtaaccgg
     9961 cggttttctc tgtttccgtt ttcgcgcgat catgtgtcgg agcaacggaa atcatgcaca
    10021 tgactccgtt acggtgcaga gcgtcataca gtggttgctg ttcaggcttc atcttcgggc
    10081 ctacataagc cattacctgt ttccagggga tgccggcttt ttcataatta tcgaattctt
    10141 cccgattctt acaccagcaa gaaaacatcg catccggttt ccggtcgaga taatagcggg
    10201 cttgactggc gttatgtacc gtgtacatga cgttaacagg cttttctgtt tctataaaat
    10261 cagccataac ttctaaaggt acatccttga tatccaaatt caggattgtt ttgcctttgc
    10321 tccattccag gcattctttt aaagttggaa ttttgaaggc tgtcacgttg ccgtttcggt
    10381 ccaccagatt gaattgttgc agttctgcat aagtgtaatc tgaaaccttt cctttcccgg
    10441 tagttgtccg gtcgatggtt tcgtcgtgca tcaatacgat tatcccgtct tttgtcaaac
    10501 gcggatctat ctcgaaaaac gattccatat aggacaaggt cttttcgaat gattcgatgc
    10561 agttctccgg atagccgtct agcattccac cacgatgtcc actgattaca atcgggcgat
    10621 cgggagcata ccggaaatag gcttgtagat cccggctgtt cttcacagta atgtaatgag
    10681 gattttgttc tttgtctgaa gccaaaagat tcccggcagg cataaaaccc cctaaaagga
    10741 gtaccaaaat aaaagatagc attttcatga tattgtattt atatagattc tttgtcaatt
    10801 atgcggctta aaagtaagac ttttttatca gtggcgtact ataaaagcac tataaaaaca
    10861 tgaaaatatg acaggcaaca agatgtgcaa agaaagaggc aggtatataa aaaattaann
    10921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn naaaaccaca atgcaaaaat acactagcta
    11101 agcttgtttg tcaaaccttt tacggataat atatgttaag ctctaatagc tattttgtca
    11161 aaaaatgttg gttatttata aactatacag attccatgta aaaactgcta attcaaatac
    11221 tttttatcgt cggaaaaagt gaaatcccat gcttaaaaag tgtccccttg gagtatataa
    11281 aatcattaat taatataggg gatgctttgg tgtggctgct tatagataaa ttcctttttg
    11341 gcgcatgcag cgaatagatg atagattatt aattgttaat acaaattaac gcattatttc
    11401 ttgcacattt acgatgtatt cgtagatttg cgatacgatc gtaaaaaata atatagaaac
    11461 atggaaagat taacaagaca ggaagaggat gtaatgcgct ggatctggca gatcgagccg
    11521 tgttttatca aagacatcct ggcgaagtat gaagagccta agcctcctta tacgacactc
    11581 gcttctattg tgaagaatct ggaacgtaag aaatacgtga aagcgaaacg ttacggaaat
    11641 acttacgaat acaggccgct gatcccacag gaggaatata aacggacgtt tatgggaagt
    11701 gtggtgaaca actatttcga gaactcttac aaggaaatgg tctccttttt tgctaaagaa
    11761 cagaagatat cgaccgatga gttgaaagag attatcgata tgattgaaaa aggacgagaa
    11821 taaactgtta aatacataat gccatgacac cggaatttgc ctacttcttg aaggtaaatg
    11881 tagcttttat actcctttat gccttctacc ggctgttctt ttataaggac accttcttta
    11941 aactacgccg taccatcttg ttggcatttt tcggggtgtc attgctttat ccgctgatga
    12001 atattcagga ttggatccgg gagcaggggc cgatagtgga agtcatacaa atgtattcag
    12061 ccattttgcc cgaaacgaca ataacccccg gcaatgttcc ccaaacaaat tggcatgatt
    12121 tgttacttcc cggtatttct tatctttatt ggagcggtgt aattgcctta tcgttccgtt
    12181 ttttagtgca gttgagcagc atcttgttac tggcacggcg gtcggaagtg actttgatcc
    12241 gtaacgtacg tgtacatctg ttgaataaac cggccggtcc tttttctttt ttccggctgg
    12301 tatttctgca tcccgacagc cattccgaga aagagatcga taagattttg gtacacgagt
    12361 gtacgcatgt cagccagtgg cattcgattg acgtgattat ttgcgaattg gtttgtatca
    12421 tctgttgggt gaatccgttt gtctggctgt tgaaaagaga ggtacgtcat aatctggaat
    12481 atttggcgga tgatacggta cttgaatcgg gctatgacag tcgtagctac caatatcacc
    12541 ttttggggtt ggcacatacc aatagatcgg tgacctcttt atctaataac tttaatatgc
    12601 tgcatctgaa aaatcggatc agcatgatga ataagaaacg ttcccggagc ataggtagga
    12661 cgaaatactt gatttttata ccggttgtgg gcgccttgct gattttaagc aatgtcgatg
    12721 cattggcccg gatcacggac gaactgacgg aaagcacgtt tgccgatgtc ttgctaccgg
    12781 aggctatctt gccgttccct tttgtcggtg atgcttctcc tgctgaaaaa cgtgaggagt
    12841 atgtgctatc ggaggaaggt attgaggctg ccagacgtgc ccgtaacccg gtgtttaccg
    12901 ttgtggaggt aatgccggaa ttccctggcg gacagggtgc tctgctgaaa ttcctggcga
    12961 cgaatgtcag atacccggaa tcggccgtta aaatatggta tagagggacg ggttagctgt
    13021 tctttcgttg ttggaaaaga cggggctatc tcggaggcag aagtgattcg tggggtaagt
    13081 ccggaactga atgaggaggc tttgcgtgtg ataaactcca tgccggtatg gtcgccgggg
    13141 aaacagcggg gcaaagtggt taatgtcaaa tatacggtac cggtaacttt ccggctttcc
    13201 ggtggaaaga aaaaaacatc ctctcgtatc gtgcagaggc agattaaaga agtcgatacg
    13261 tccggtcgtg tctttacggt agtgcaacag atgccggaat ttccgagtgg acaggcttcg
    13321 ttgttgaaat atctggcaac acgcataaaa tatccggcta ttgctcagga gaatggaata
    13381 caaggacgtg tctcttgctc tttcgttgtc gacacggatg gaagtttgaa aaatattgaa
    13441 gtgatccgtg gaatcgatcc ttcgctggac agggaggctg tccgggtgat ccgggaaatg
    13501 ccgaaatgga atcctggcgt acaaaacaat atggctgtag ccgtaaaata tacggttccg
    13561 gttactttcc gtttgcagta attgaccaga atcggtcatt aatacgatac cattatgaaa
    13621 tgtaagtttt ctctattact gtttctttgc gtactgtccc tttggggaca ggcgcagagt
    13681 cttaatcttc aggaattggt caataaaaaa caatttcagg aagttgtagc acgtgcggat
    13741 agtcttactc ctgccgattc agccgattat gctacaatgt cggcaatcgg gcaggcgtat
    13801 gagggactgt tgcgctataa ggaggcctat cagtgttttt ctcattgctt gaagatggat
    13861 acgaacaatg tggatgcatt gaacgccgtt gccaggaatg cgatcaattt cggaaggata
    13921 gcggaagcta aacaatgtta tcgtaaagta ttgggaaccg acagcatgaa cttctatgcc
    13981 aactatcagt tggcgcgtct ctattatcag ttgggagatt atggtcgagc gacggaacac
    14041 tatcatatac ttgcttccat cgaaggtgaa aatccttcta tcctgaccgg gctggctgat
    14101 tgccatatta aaagagggac cggtcctaat acgatgatcg ctctttcttt gtatgcccgt
    14161 gctttggagc tgaacccgga aaatgtacgt gtggcatctt ctctgataaa tacgttattg
    14221 cggatggggg acggacaggg agctttgcag gtgtgcgata ccgccttgtt ctataatccg
    14281 gataacagcc agatacggca gagtaaaggg atggctctct atatgacgaa agattataag
    14341 caggccgatt cagtctatac cggtctattg gccgatggcg attcttcttt tttgaatctt
    14401 aaatatgcgg gggcggcccg ctatatgtcc ggtcatgcac ttgatggggt cgagctgctg
    14461 gagaaggcct atgaaataga ttcgacggat gtggaaacag tcatgttgta tggcgcttcc
    14521 ctgggaaaaa catacgaccg taaacgggct tatgagcttt tcgatctggc ggaaacgaat
    14581 atgcagccga aaaaattcct agttaatatg ttgacgacct tccgaggtga tgccttggaa
    14641 agggacggcc gttggcccga agcggaaaag ctgtattatg ccgcatggaa ggaagaccca
    14701 acccagttgc acttcctgta taagatcagt acacaatact gggatgtcga tccgggactc
    14761 tttcagcagg aggaaaaatt gcaaaagacg attttcagta gatacactta cctgacagcc
    14821 tatatgaaga cagacaagtc gcaaaagtat ctttataatt accgcccttt cttggaagcg
    14881 gtttgtgaag atgccttttt ccggaatgcc gatgaagtga cgatgttggc tcccgatggg
    14941 aagaagacga agttggctgt cgctgatctg cgtgccttgg tcgcccaact gccgcagatg
    15001 ccggaagatg aacgtttgag gcgcgagaag at
//
