LOCUS       c00033_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PNIEANPJ_72.
ACCESSION   c00033_gnlPro..
VERSION     c00033_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:40:58
            Original ID  :: gnl|Prokka|PNIEANPJ_72
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 19020
            Orig. end    :: 42269
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[29020:32269]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1475..2932
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_22"
                     /sec_met_domain="FGGY_C (E-value: 3.5e-38, bitscore: 122.6,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 5.4e-80, bitscore: 259.7,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFIQSMEGMKELTKDIDRTQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARSLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3044..3979)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg33_23"
                     /sec_met_domain="LysR_substrate (E-value: 1.8e-33,
                     bitscore: 106.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.4e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAIEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYIYQKEQ
                     LLLAVPKNYSVNTRLQEYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4095..5519
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_24"
                     /sec_met_domain="Lyase_1 (E-value: 8.6e-95, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 3.2e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5628..7313)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_25"
                     /sec_met_domain="FTHFS (E-value: 1.6e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_26"
                     /sec_met_domain="OKR_DC_1_C (E-value: 9.3e-14, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_27"
                     /sec_met_domain="Spermine_synth (E-value: 1.2e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 1.7e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_28"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.4e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 6.7e-36,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_29"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 7.2e-15,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKNRLS"
     CDS             13197..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_30"
                     /sec_met_domain="PAD_porph (E-value: 2.7e-128, bitscore:
                     418.9, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRLSDISDTKTLRTGFPDICRAIKEKETDMEVTEKNRTKYRMPGE
                     FEPHEGCVMIWPERPGSWNYGAREAQKAFVKVAEAIGESEKVYMLVSKAQMENAKNQLG
                     NVSGVTLLECETDDAWARDVGATMVLDEKGAVCGVDWQFNAWGGTFDGLYRNWEKDDRV
                     AAFICRTLGCPCLDARPFVLEGGSIHSDGEGTLIVTEACLLSQGRNPQMSREQIEEQLK
                     YWLGVHKIIWLPCGIYQDETNEHVDNVCAFVRPGEVVLAWTEDETDPQYAMSLADLKVL
                     EQETDAKGRKFKIHKLPIPQKPVCLTQEDVDGFVFEEGEDEREAGERMAASYVNFYISN
                     GGIILPQFGDENDKRAVEILQKCFPERRIYPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14488..15366
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_31"
                     /sec_met_domain="CN_hydrolase (E-value: 2.9e-56, bitscore:
                     181.9, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGIIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELSGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15594..16055
                     /locus_tag="ctg33_32"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETEFPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIILLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16258..20967
                     /locus_tag="ctg33_33"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVDNAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQVAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDIFEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASEDSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     EDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQMNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLVLDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILKIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGAFIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYELVFKTESTEPEKIVNTAKA
                     RGDISPETAAQQEVYVKAKAEPTVTPTPSATPKPTETPKPTETPKPTEVPKPTEQPKVT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20964..21851
                     /locus_tag="ctg33_34"
                     /transl_table=11
                     /translation="MKKFRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22043..23134
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.6; E-value: 2.8e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_35"
                     /sec_met_domain="Peripla_BP_3 (E-value: 1.7e-33, bitscore:
                     107.6, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKKMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 tatggagaaa gctcttgaag atgtaaacaa agcagagtgt aatgcgctgg ttgttttcct
       61 tggaaacttc ggacctgaaa ctcctgaaac tctgatcgca gagagatttg acggaccttg
      121 tatgtatgta gcagcagcag aaggtgacgg tgatatgatc aacggcagag gtgatgctta
      181 ctgtggtatg cttaactgct cctacaactt aaaaatgcgt catctgaaag catatattcc
      241 ggaatatcct gttggaacag cagatgatat tgcaaagatg atcgctgatt tcgtaccggt
      301 tgcacgtgca gtcatcggtg tcagcaatct taagatcatt actttcggac cacgtccaca
      361 ggacttcttc gcatgcaacg cacctattaa aggcctctat gagctgggtg ttgagattga
      421 agagaactca gagcttgatc ttcttgtttc tttcaaagag catgaaaatg atcctcgtat
      481 cccggaagtt tgtgcagata tggcaaaaga gatgggcgaa ggcaaatatt atgctgacct
      541 taatgtgaaa atggcacagt ttgagcttac acttcttgac tgggcagagg ctcataaggg
      601 agcaagaaaa tacgttgcat ttgctgacaa atgttggcct gcattcccgt cacagtttgg
      661 atttgaacct tgctatgtaa atagccgtct ggtttccaga ggaattccgg tatcctgtga
      721 ggttgatatc tacggagcac tcagcgagta catcggactt tgcatttcca atgatgcagt
      781 tacactgctt gatatcaaca actctgttcc acagtatatc tatgatgaag atattaaagg
      841 aaaatacgat tataagctta ctgatacatt tatgggattc cattgtggaa atactcctgc
      901 atgcaagatg tgtgattcca gagctgttaa atatcagctg atccagcaca gacttcttga
      961 gccggcagga tctgaaccag acttcacaag aggaactctt gaaggtgata tcgctgcatc
     1021 tgacattaca ttctatcgtt tacagtgcaa ttccgagggc gagctggttt cttatgttgc
     1081 agaaggtgaa gtactggatg tacctacaag atcattcggt ggtatcggta ttttcgcaat
     1141 caaagaaatg ggaagattct accgtcacgt actgatcgag ggcaactatc cgcatcatgg
     1201 agcagttatg tttggacatt acggaaaagc attctatgag gtagtgaaat tccttggact
     1261 ggatgttaag aagattggat acaaccagcc ggcaggtgta agatatccga cagagaatcc
     1321 atggggttaa tgagaaatca gtaaaacggg ttattaatgt tcatgtgatg tgaatgaatc
     1381 tgaatacaga ataaataaac tgacactata ttaaaggcat cccggggctt tgctctggga
     1441 tgtattagat tagaaataga aaaggagcgc acttatgtat tatatcggta ttgatcttgg
     1501 tacttccgct gtaaaacttc ttcttatgga agaatcagga aaaatctgta acatcgtatc
     1561 cagagaatat ccattattct tcccacatcc gggctggtct gagcagaaac cggaggactg
     1621 gttcatacag agcatggaag gcatgaaaga actgacaaag gatattgaca gaactcaagt
     1681 agcaggaatt ggttttggtg gccagatgca tggccttgta actcttgaca aagatgataa
     1741 tgtaatccgt cctgcaatcc tctggaatga cggacgtaca ggcgaagaga cagaatatct
     1801 gaatacagtg atcggaaaag acaaactttc acagtataca gcaaatattg ctttcgcagg
     1861 cttcacagca ccgaagatcc tctggatgca gaaaaatgag cctgagaact ttaagaaggt
     1921 agtaaagatt atgcttccta aggattatct ggcatatcgt ctgtccggtt ctttttgtac
     1981 agatgtttct gatgcttccg gtatgcttct tcttgatgtg aagaaccgct gctggtcaaa
     2041 agaaatgctg gagatctgtg gaatcacaga agagcagctt ccgaaactgt atgagagttg
     2101 ggaagtagta ggaactctga aacctgagat tgcgaaagaa cttggattca gtgagaatgt
     2161 aaaagttgtt gcaggtgcag gtgacaatgc ggcagctgct gtaggaacag gtacagttgg
     2221 tgacggtcag tgtaatattt ctcttggaac atccggaact gtgtttattt ccagtaaaaa
     2281 ctttggtgtg gacgaaaata acgcacttca ttctttctgt catgcagatg gaagctatca
     2341 tctgatggga tgcatgctca gcgcagcttc ctgtaacaaa tggtgggcag aggagattct
     2401 tcagacaaag gatttcgcag cagagcaggc tccaattcag aagctgggag agaatcatgt
     2461 attcttcctt ccatatttga tgggagaacg ttcacctcat aataatcctg atgcaagagg
     2521 tgtattcttc gggatgtcca tggacagcac aagagcagac atgacacagg ctgttctgga
     2581 aggtgttgcc tttggtcttc gtgattccct ggaagttgca agaagccttg gaatcaagat
     2641 tgagagaacc aagatctgcg gtggcggagc taagagccca ctgtggaaga agatcattgc
     2701 aaacgttatg aacctgaagg ttgatgttct ggagaacgaa gaaggaccgt ccatgggtgg
     2761 agctatgctg gcagcagtag gctgtggtgc ttacccggat gtagaaacca tcggtaagaa
     2821 atttgccaaa gttgttgata cagtagaacc ggatcctgaa ctggttgcaa aatatgaaga
     2881 gagatatcag aagttcagaa ctctgtatcc ggctatgaag ccactgttct aatcgaatat
     2941 ctgcctgaca tactggggtt gttgtgctta tttagcacaa caaccccatt ttgacgtaca
     3001 tctgatgatg accaatcacc atagcctatt tgattatgac atatcaggaa aagggcagct
     3061 tcaggaattc ttccatggct ctgctgatat agcggccttt cttccagtaa aaaaacacag
     3121 tgcgtttact gctctgaccg ggcagcttat aaaaaacaag ttctgaattt gttggaactc
     3181 tggagagcag aagatccccg atgaaagtga tacccattcc caaacatgca atattatagg
     3241 cagtcatctg ctgatccagg cgaaatacta cagaaggcga aaagtgattt tcctgacaaa
     3301 tggtaagtgc acgcttaccg gtatcattat ctgaacgaag aataataaat ggttcgttct
     3361 cgaatttgtt taatggaaca gaaggaatat gagaagaacg gaactgcccg ttccggattt
     3421 cctcaatagg aatctgatat tcctgtagtc tggtatttac tgaataattt ttgggaaccg
     3481 ctagaagaag ttgttctttc tggtagatat aatgttcaaa aatctggtta tccagaatac
     3541 agttatcaat caccagatct aactttccgg cctggagaaa ctgggatagc tttgctgtac
     3601 tttcttctac aagagaaatt tgaacatggg ggaatttttg ggaaaaatca gcaataaggg
     3661 gaggcagaat ccacgaagaa aaaaagttac tgccacctac attaagagtt cctgttttga
     3721 gatttcccag atccagtagg tagttttcga gattattttc aatatccatg actttttcaa
     3781 tagcctgtat ataatgtttt ccgacttcag ttaactgtaa aggtttggta cttcgatcaa
     3841 aaataggata accaatgcgg ttttccacac gttttacatt tgcacttaaa gaaggctgcg
     3901 aaatgaaaag agcagcagca gctttggaaa agcttttttc cttgtatacc tcatagatgt
     3961 attccattcc ctgaaacata taaactcctc cgatatataa cttaaacact atatgtttta
     4021 taaaaatata tgtatttgat tatattatag cagagatata taatgagggc aaatacatgg
     4081 gagggcgaat aactatgaaa aaaacagact atcgtgtaga aagggattct attggtgtaa
     4141 aggatattcc ggaagatgta tattatggag tacaatcctt acgtgcggct gaaaatttcc
     4201 acattacggg gctgaatatg catccggaaa ttattaacag tcttgcatac ataaaaaaag
     4261 cagcagcgat aaccaattgt gaggtggggc ttcttgagaa gaaaaaagca caggcgattg
     4321 tccaggcatg tgatgaaatt gtttcaggaa aattccataa tgaatttatt gtggatcctg
     4381 ttcagggagg agctggcaca tctttaaata tgaatgccaa tgaagtaatt gcaaatcgcg
     4441 cgattgagat actgggagga aaaaagggcg attatacaat tataaatcct aacgatgatg
     4501 tgaattgtgg acagtctacc aatgacgtga ttcctactgc cggtaaaatg acttctcttc
     4561 gtttgttgca gaatctgaaa aaacagcttc ttcgcctcta tgatgctctt aatgaaaaag
     4621 ctacagagtt tgatcacata ataaaaatgg ggcgtacaca gatgcaggat gcagtaccaa
     4681 ttcgtctggg acaggaattt aaggcatatt cggtagcaat catgcgtgat atccacagaa
     4741 tggataaagc aatggatgaa atgcggactc ttaatatggg aggtactgct attggaacag
     4801 gaattaatgc agatgagggc tatctgagaa gaattgttcc aaatctcact gaaatatcgg
     4861 gaatggactt tatacaggct tttgatctga ttgattccac tcagaatctg gatccatttg
     4921 tagctgtttc cggtgctgtg aaagcatgtg cggtaactct ttccaaaatg tcaaatgatc
     4981 tccgtctgat gtcctccggt ccacgtactg gttttgggga gattaatctt ccggcaaaac
     5041 agaatggttc ctctattatg ccaggtaaag ttaatccggt tattcctgaa gtagtgaatc
     5101 aggttgcttt taatattatt ggtaatgatg ttaccattac catggctgca gaggctggtc
     5161 agctggaatt aaatgcgttt gagccgatta ttttctattg catgtttcag tctatcgata
     5221 ctcttggcta tgcagtccag acattggtag ataattgtat tgtaggaatt acggcaaatg
     5281 aagaaagatg ccgttatctg gtagaaaaca gtgtaggtat tatcactgca atcagccccc
     5341 atcttggata tcagaaggct gcggatattg caaaaaaggc aattaagaca ggcgaatctg
     5401 taagaagtct gattctgaaa gaaaagctta tggacgagga tgaacttaat cgcattctgg
     5461 atccgatcca tatgacggaa cctggtattt ccggaaaaga ttatcttata aaaaaataaa
     5521 gaaaaaaaca ggcgggaaaa tcttcccgcc tgtaaaatcg tctggacaca tatcatatat
     5581 aaatatgatt tttatatttt tgaattattc gattgatttc aaccggatta gaacagacct
     5641 gtgatcttac ctgtttcgtc tacgtcgatt ctctcagcag ccggaacttt aggaagacct
     5701 ggcattgtca tgatctcgcc tgtaagagct acgatgaatc ctgcaccagc ggaaatcttc
     5761 aggttacgta ctgtaacttc gaagtcagta ggagcaccca gtttagtctg gtcatctgtt
     5821 aagctgtact gtgtcttagc tacacagatc gggcagttgc caaagccaag agcttctaac
     5881 tgtttcgcct gtttctgagc gttagctgtc agaactactt tcttaccgcc atatactttc
     5941 tgaacgatct ggttcagttt gtcttcgata gaaccttcca gttcatatgc ataggagaag
     6001 tcgtttggtt cttcaacaag acggataact tcttctgcaa gtttgattcc gccttcgccg
     6061 ccttttgccc acacttcaga aagagcaacg ttaacgccca gttctttaca tttagcttct
     6121 acaaagtcaa gctctgcttt tgtatctgta gggaatgcgt tgatagcaac aacacatgga
     6181 agtttgtata cgtttttgat gttggaaacg tgttttaaca ggttcgggat acctttttca
     6241 agagcttcca ggttttcatt gttaaggtca gctttagcaa cgccgccgtt gtatttcagg
     6301 gcacgtactg tagctacgat tacaactgcg cttggtttta aaccagccat acggcatttg
     6361 atatcaagga atttctcagc accaaggtca gcaccgaaac cagcttctgt gattgcataa
     6421 tcagcaagct tcatagccat ctttgtagct gttacagagt tacatccatg agcgatgttt
     6481 gcgaatggtc cgccatgtac gattgcagga acgtgttcca gagtctgtac aaggtttggt
     6541 ttcagagcat cttttaacag ggctgtcata gcgccttctg cgtgaaggtc acctgctgtt
     6601 acaggtttct gctcggaaac ttttccgtat gtatatccga tgatgatctt ggataatctt
     6661 tctttcaggt ctttgatgtc gcttgcaaga cagagaactg ccatgatctc agatgcaact
     6721 gtgatgtcgt atccgtcttc acgaggcata ccgtttgtct ttccgccaag accatctact
     6781 acgttacgaa gctgacggtc gttcatatct acacatcttc tccatgtgat cttacgtggg
     6841 tcgatgttta atgcattgcc ctggaagata tggttatcga tcatagctgc cagtaagttg
     6901 ttagctgcgc caatggcatg gaagtcacct gtgaagtgaa ggttaatatc ttccatagga
     6961 acaacctgtg catatccgcc gcctgctgca ccacctttta caccgaatac cggtcctaag
     7021 gatggctcac gaagagctac cataacactc ttgccaagtc tctgcatacc atctgcaaga
     7081 cctacagtag tagtagtttt accttctcct gctggagttg ggttgatagc tgtaacgagg
     7141 attaattttc cgtccttctt atcactttct ttcagaagat tgtagtcgat ttttgctttg
     7201 tattttccgt actgctccag atatttgtcg tcaatacctg ctttctctgc gatctgagta
     7261 attggaagca tctcgcattc ctgtgcaatt tcaatgtctg atttgaatcc cataattgtt
     7321 tttctccttt cgtttccgca taacatgaaa aacttctgtt gctgttcact ccgcgatcag
     7381 caacaattat taattgaaag aagtattggc cggtctgcct ggtattcctg atttctgccc
     7441 tgaaagttat aaaaaaaggc cagtatctga atatttcaaa tactgcccag acggtcggct
     7501 cccacaaacc tccgactcca cgtggtttgc actccactct ttccgtcagt actcgaaggt
     7561 tctttcaatt gatgaataca atatatcatt ttgagaaaaa aatgtcaaga aaatttttgc
     7621 tgaaacgtca aaaaatgtga gtaaactgga taaaagttgt gcaaattgat aagagaagag
     7681 aatcgtaatc cctggtaatg aaagaaaata cgttttctca agggaagaaa ttgttaaaaa
     7741 ataaacacat ttttccctga taaatgaaga aaatataaaa agcgggtaaa gctagagcgt
     7801 gtctgaaaaa tcattcccgc aatctgtacg cccccacttt gcgggatatt tcactcgaat
     7861 tcagttgccg tagcccgcta cggcgccttc atccgggcaa aatatcccac aaattgtgac
     7921 gcacatcttg cagaaagcct ttttcagaca cgctctagtg caaaatatgg aaaatggaat
     7981 tgacaacagt tcagaagata tgttattctc atctttagta tgaaaagaca ctatcgtttt
     8041 catgcaaata tttgctcaca ttcagagaca gtttctgaat gttaagccat acggacaggc
     8101 ggggcagttg ccgggtggga gacaccacat tattgattga gttagaagct caaattttat
     8161 aagttgatta ctttataata atcagtgcgt aagcacacat catcttgtga aacggtcaat
     8221 aagagcatag catatatttg ccagcgattg aagacgacag cagtcatgaa tatttcagaa
     8281 tacgggaaca ggcacaggat acagacggat ttatacggga aatccggtca gtatataaag
     8341 agacagagcc tgagaaattc tatagatcat gagagaagca gatggtgaat gaacttatct
     8401 gcttcttttt ttgtgcagat atagcaaata tatatataga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatt attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc tatttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatcgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgcc tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaat
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgattttcc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga gaatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gagggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgctct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagaa gaactggatc gtatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcttggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt aatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagaaccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggaggt acctttgacg ggctttaccg gaactgggaa aaggatgaca
    13681 gggtggctgc ctttatctgc aggactctcg gttgtccatg tctggatgcc agaccttttg
    13741 tgctggaggg cggttccatc cattctgacg gagaggggac tctgattgtt acagaggcct
    13801 gtcttctgag tcagggacgt aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccag gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttatgtgaa tttctatatt tccaatggag
    14221 gaatcatcct tccacagttt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat acctgaaagt tatgaaaaaa cttacttatg
    14461 taaacaggag caggaggaac agacaggatg agaaatgtaa cagtggcagc agttcagatg
    14521 aaatgcagta aaagtgtgga gaaaaatatt gcccatgcag aggaactggt gcgtcaggca
    14581 gcagcaaagg gagctgagat tgttcttctt ccggagcttt ttgaacggcc ctatttctgc
    14641 caggagcgca gatatgagta ttatgaatat gcgcagactg cagaggaaaa ccctgcagtg
    14701 cgtcatttca gcagggtagc ggcagagctg gggattgtga tcccggtcag cttttatgaa
    14761 aaagaggtca ataataccta taacagcgtt gcggttctgg atgcagatgg gaagaatctc
    14821 ggcgtttacc ggaaaacaca tattccggat gaccattatt atcaggaaaa attctatttc
    14881 acaccgggag ataccggctt taaggttttt gataccagat ttggaatcat tggagttgga
    14941 atctgctggg atcagtggtt cccggaaacg gcaagatgta tggcactgca gggagcagag
    15001 cttctctttt atcccactgc catcggcagt gaacccatcc tggaatgtga cagcatggaa
    15061 cactggagaa gatgtatgca gggacacgct gcctccaacc tgatccctgt gatcgctgcc
    15121 aacagaatcg gtgaggaaac agtagagcca tgtccggaaa acggaatgca gaaatctgct
    15181 cttaattttt acggctcttc ttttatcaca gacaacacag gtgctctctg tgcagaactg
    15241 tccggagggg aagagggggt gcttgtaagc acttttgacc tggatgcatt aaaggcagac
    15301 agactgaact ggggactttt cagagaccgc agaccggaaa tgtatgcaaa aattgtcggg
    15361 aaatgacata caagccaaaa ttccattgcc gcaggcaatc tggaatgaat tttggctcag
    15421 ttactgagaa cggagtgaac agtaactgag tttataagaa tttcataaaa agtttatgat
    15481 tatattagtt gctacctgcg gtatatatgg taaaataaga gtacgaacgt tactgataac
    15541 ggagagagca gtagagtttt gatatgtatt tctggcaaaa tggagtgtag aagatgaaca
    15601 gaaaagaatt tttggaaatc ctgagaagcc agcttgccgg gcagatgcag gagggcaaag
    15661 cagcagcaca tatcaggtat tatgaagatt atatacagtc tcaggtacgt ggcggacgtt
    15721 cagagcagga agtactgcag gaactgggag acccgcatct gatagcaaaa actctgatcg
    15781 atacagatga tggaagtaca caggaagatt acggagagta ttcttcttac ggaagcagtt
    15841 atggcaatga gacagagttt cctcatcagc aggagaaaag atggaaaaaa gtaatcgatc
    15901 tttctacctg gcatggcagg gctgttgtta ttgcagcagc ggctgttata attattttac
    15961 tgatactgat aatcggagtt gcgattccgt tttttataat tcttgcaatt attctttatt
    16021 ttctttcatg gctgaagaaa agaaatgatc aatgaaaatc tatgcagggt ttcagaaaag
    16081 gaaccctgcg cagaatctta aaatcttaag tgtaaacgtt cttgtttcac gatattaatt
    16141 ccccttgaat atttataatc atacaatctc aacttatttc tattctttaa tcctgccagg
    16201 tgcagggaaa aatcccacat tcatttttat attttttgtt cggaaaggag acggaaaatg
    16261 aaacacaatt tcaaactgaa agaacgcctt ggagctttgc tgcttgcaat gctttttatt
    16321 ctgcaggcaa ttctggggct tgtgcctgtc tgcgtaactc aggcggcacc gttaactgta
    16381 gaaacatggg acagtgacaa ggtggtagat tatggttatc gctttaacat gaagtttcag
    16441 cccggaatta ccacatatga atcttttggg tgtgataatc tggacaggga agctttttca
    16501 gacaatggaa aaagcgaacg tgatacagag tgcgttcgtg taggagcgga ctataaagcc
    16561 ggaagcgcag ggatgcgtta taacaatgta ggaaaagatg gaaatggaaa tattgttgat
    16621 gtcagactca ttcttgtggg agtagacaat gcagaacccc gttatgatct gcgcactgca
    16681 gaatcgattg ttcagaataa aggcggagct acgtttgcat ggaaagataa tgaagcttat
    16741 ccaatggttg gcttttccaa aaacagtatc ggtgtattta tttattctgt aggatacgca
    16801 aaggttaaat ttcagtttct gaagcatgga acagaagaaa cactgccgat cagtggacat
    16861 ggaaccatac gtgatattga tgcgggacag ggagtccgta ttccgtcaga cagcagtctg
    16921 gataatgcat atgttctgaa aaacaatgat tatctgacgg tagatgggaa ttctgtaagc
    16981 tcaccccttg gttccgttga gccggatgat ccgagaggat ggctgaatct tttttataat
    17041 acagataatt ttacggtaga attctgtcat cagttcagac tggataaatg ggataaaagc
    17101 cgtgaagatg ccattgcaaa agccggttct caggaaagat gggcagagat tacaagaaat
    17161 aaatatctgg atccatcagg caacagttat tgtccgaact ttaaaggaca gaaatactgc
    17221 aaagcatatg catattttga ttttacatcc tattgtttcg gtgatgttga gatgaaaaaa
    17281 gcgcctgaga aacgtgtggg agaggcaaac tgtacatggg aacaggtagc tgccgcatca
    17341 aaagaaaaac cttttggcat tcgtcaggga caggaatttc agtatatgat ccgggcggag
    17401 gtgacaccca atagactgaa atcctttgtg gtacaggata tatttgagga ttgtcttact
    17461 atagaggatg catcaaaagt cagtattgtg aatgatgcag ggcagacagt gacagactgg
    17521 tttgatgttg ctgttgaagg acagaaagtg acctgcaggg ccaaagcaga gagccttcag
    17581 gatgaagcat ttacagataa tcagacttac acatttactt taaaagtacg ccagagaccg
    17641 gaatcagaaa ttaacatttc aaaatacctt gcagaggatg gatacagtat tcttgtacca
    17701 aaccatgcat ccatgagtta tgaacgtaca aacggaagcg gagatacaat ggatacggaa
    17761 acagtgtggg taaagggtgt gattccaccg gaactggaag taaagaaaaa tacttctcag
    17821 tatgaatgga aaacgggaga tatcatagat tatgaggttc tggtttctca gacaaaacag
    17881 gatgtaaaag cagtaaatgt tgttattaca gacgagcttc catcatgtct gcagcttctg
    17941 gaagggcagt atgctgtaga gacaagtcag ggaggtgaga actgtacgct taccggacag
    18001 ggagaaaatg gatggaaagc agagtgtccg tccctgaagt atggggagac gatcacaatc
    18061 cgttttaaat gtcaggcatc tgaggattcc aatggacagg aatgggaaaa tattgtgact
    18121 gcaacagcgg ataatctgat caatcctgag acaggagaac aggaatccag aaaggatatg
    18181 gcagaagtat ggccgaacag tccacagctt gaaattgaca aaacagcaga taaatatgag
    18241 tggcaggcag gagagcaggt agcttaccgg atcgtggtga ataatgtaac ggcaggaacg
    18301 attgcgaaag atgtaactat tactgatatt ggtctgccgc agggactggt tctggcaggt
    18361 ggtgcacaga gcatggaagt actgggagtt cagcagcagg taaactatcc tgtaccggat
    18421 aagaaaacag gacaggcata tgaagcgaga cctgtggatt ctcagttgaa tgcagatgag
    18481 aacggatttt ccttttattg ttcttatgta ccatacagtc agcctgtaac gattattttc
    18541 cattgtatcg cacaggaaga ggcaaatgga cacgaaagcg taaatgcagc aactgtaaaa
    18601 gctgctaata cagatgagag atctgatgat gcagaagtat atgtaaattc aggagaattc
    18661 tggattgaga aatctgcaga tcattatgaa tggcaggtcg gagaacaggt acagtacaat
    18721 gtggtggtgg agaataaaaa agcaggtaca gtggcccgga acgtaactgt ctgggatacc
    18781 ggtatgccgg caggacttgc gctttcatcg gcagaggatg tatcggtaag cggaatccca
    18841 cagaatatta cgcagctgac agcagggacc gaagatgttt tgaaccagct caatccggaa
    18901 ttttataatg agacatcaga gaaaccggtg aattatgaat ttcttcagga gggaagcgga
    18961 tggagactga atatttcaga tcttccggca aatactccgg ttatgatttc tttcctttgc
    19021 acagttacgg aagcggcaaa tggaatggaa agcattaatg ttgccaatgt gcaggcgcag
    19081 aatgcccctg tttcgcagga tgacgcagaa gtgtatgtaa atacagcagt tctttctatt
    19141 gagaaaagtt ttcagaatcc atatctggca gccggggacg gacgtgcgga aaatgaattc
    19201 cgggtaggag aacagatgaa ttatcaggtt acggttaata atcttcagaa gggatctatc
    19261 gcaagaaatc ttgtgatcag tgatctttcc cttcctgaag ggctggttct ggacggagct
    19321 gaagatgctg ttactgtaag cggtgttccg gctgttattc agaatccggt ggcaggaact
    19381 gatgatgcag gaaatcagct gaatccggaa aattataaag aaacagtgga aaaaccggtc
    19441 agctgtcagg ttacacgtca gggaaccgga tggatcgtga cgatttcaga tcttccgtat
    19501 cagacacctg tgactgttaa tttccgctgt actgcgcagg aaagcgtaaa tgggatggag
    19561 attgtaaata cagcacaggc atatgcagat aatgcacaga aagtaaagga ctcctcaaaa
    19621 atctgggtga actcgcctgt tcttaaagta gagaagacga cggacaaacc attttacaaa
    19681 tatggtgata ttattacata ccgcattgtc ctgacacagg agcagaccgg atgtgtggcg
    19741 cgtaatgtta ctctgcagga tgtgatcgat actcagggag tacgtcttct gaaggattcg
    19801 gtgattctga tggatgagaa aggaaatgtg gcagatgctg atgtacagat caatgatgat
    19861 aacactttcc tgatgtcaac aggcaggaca ctggtcaggg acagcagata tagtatctgc
    19921 gataatgata aaggcggtct ttttgagcag gtaatgtata atcctctgga ctgtcaggaa
    19981 cagaaaagta tgatcgtgga atatcaggca gcggtgattg atgcagccct ggcaggacag
    20041 aaagtgcaca atactgcagt tgcagacagc agtgaaaaga tacctgcaac cggggaaaca
    20101 gagacagagg tacacagtcc gattctgaaa attgtgaagg aatcagataa gaaagagtat
    20161 gcgtccggtg agaaaggata ctataagctg acagtaagac aactgcgtga ggatgtcaca
    20221 gatcagaata ttgttatcga agataaactg gaaacccaag gggctttcat tgtaaaagac
    20281 agcatttttg tgaagaaaaa cggtatagaa ctgaaagatg ccaaaataga ggcagatgat
    20341 acaggatttg taattcagac aggagcatcg ttgtcagata tggataaaat tgaagtctgt
    20401 tatgaactgg tatttaaaac agaaagcaca gagcctgaaa aaattgtaaa cacagcgaaa
    20461 gcaagaggtg atatttcacc ggaaactgct gcgcagcagg aggtatatgt gaaagcaaaa
    20521 gcagaaccca ctgtcacacc aacaccgtct gccacaccga aaccaacaga aacaccaaag
    20581 ccgacagaga caccaaaacc aacagaagta ccgaaaccaa cagagcagcc aaaagtcaca
    20641 ccaacaccat ctgtaccggg aacctgcccg aaaatgactc ctgtaccgac gaaagcaccg
    20701 ttagcatctt ataatggtgg aaataatgga ggcacaactt ccggaagcgg aggcagcagt
    20761 tacgcaaatt cgggtggata ttccggtgga tatggaagct atcagggtgg ttccatggca
    20821 ggaagttcta aaacaggaga tgtcagaccg tttaaaatga tggctgttct tggacttatc
    20881 ggaatgggac tgctgacagg aggtgtggtg atctacagaa gaactgtttc cgggaagaga
    20941 aatataaagg gtatgccgcg gaaatgaaaa aattcagaac atttgcagta agtatgatca
    21001 tagcagcaat cgggcttctt atatattgtg ccggcttcta tataaaaagt tatgaacaga
    21061 atcttgcagc aaggcaggaa tatgcagagc tttcccaaat ggcaggggtg aagaacagag
    21121 aaggtgccgg attattggca gatggcaaaa aaactgatga agacagcagt acaaaaaaca
    21181 gtgaaaaaaa acgcaggaaa aaacagagaa gatcttctga atcaaaaaac aaaaactgta
    21241 cagatgaaat cagggaatcc ttcgggattt cctgggaaaa tttaagaaag atcaactctc
    21301 agacagttgc ctggattact gtcccgggag ccgatatttc ttatcctgta gttcaggcgg
    21361 cagatgatga atattacctg aaacataatt tcagaggaga ggaagatctg tttggatgta
    21421 tttttctgga acatgacata aaaaagaatt ttacagattc ccacagtatt ctttacgggc
    21481 ataatataga aggtaatatg atgtttgcaa atctgaaccg ttatgaacag cctgaatttc
    21541 tgaaaaaatg tcctgaaatt gagatcacaa cacccaaaag aaagtttctg tacaaaattt
    21601 tttctgtgga acaggcatct tcccaaagcc cggcatttga atatggatac aagttatcca
    21661 gtcctgcata caggagacaa ttatctatat tgaaaaataa ttccatgtat gacacaggag
    21721 tagagcctga tgaaagggag agaatggtga ctctgatcac ctgtaattca cgtctggata
    21781 aagaaatacg tatggcggta catgggattt gccatgaatg ttatggtata gaaaaagctg
    21841 agccgaagtg atgttgaaat caatcggata ttggtaactt tcgtaaagga tgaactgtta
    21901 ctgtttatac atcactatcc ctcgaggtgt tttggaaaaa actaatgaaa aatctctcaa
    21961 tattttgtat aatttatgca taaaaaacaa cttgttcgta cgtgcgtaca agttgtatcc
    22021 taaatacagg agggaagaag acatgacaga taatggaaag ccgaaatatt tctcactgat
    22081 ggaacagctc agaagtgata ttatgtcagg agctatccga ccgggagaga agcttccttc
    22141 agaaaacgag ctttcacaga aatattccct gagcagacat acagttcgta aagcactggg
    22201 aatcctggag caggacggat atgtagaggc atttcacgga agaggtactt attgctctga
    22261 gaatatgcgc catataaaga attcaaagaa tattgcggta gtgaccacat atatttctga
    22321 ttatattttt ccgagactga tacagggaat ggataatgtc ctttcagaaa gcggttacag
    22381 tattatcctg aaaaacacag caaacagcag acagaaagag gccagatgtc tggaggaact
    22441 tctgaagaaa gatattgatg gactgatcat tgaaccaagc aaaagtgaga tgatctgtaa
    22501 acacagaaat ctttatcaga atctggataa atttgaaatt ccgtatgtgt ttattcaggg
    22561 aatctattca gaaatgaggg ataaacctca tattcttatg gatgatgcac agggaggcta
    22621 tcttgtaaca aaatatctgc tggaactggg acataaaaag atcaagggtt tctttaaggc
    22681 agacgatatg cagggactgg agcgccacaa gggatatgtg aaggccttac aggagtcagg
    22741 gattgcctat gatcctgatg atgttgtctg gtttcataca gaggacagga aagtaaaacc
    22801 tgcactgatg gcaaaaaaaa tggtacagag cggacagctt ccggatggaa tcgtctgtta
    22861 caatgatcag attgctgttc aggttatgga agaactggag aaaatgggag tcaggatacc
    22921 ggatgatatt tccattaccg gttatgacaa ttcactgtat gctcagcgag gaagcggaat
    22981 cacaacgata gctcatccgc aggaaaagct gggagaaatg gcagcagagc ttatacttga
    23041 gaagatcaac ggagttcctg aagaagaaag taaggttgaa agattgattt atccggaact
    23101 gatcatacgg ggatcatgca gaaaaatatt gtaaacaaat gaaataaata aaaaataaaa
    23161 ataaatccag gaggaatttt atcatgaaaa caggaagaaa ctataagttc tggttttgta
    23221 caggttcaca agatctttac ggagatgag
//
