GCA_018785825.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaDFKDNBMG_5 (original name was: gnl|Prokka|DFKDNBMG_5)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS	1	44,360

gnlProkkaDFKDNBMG_99 (original name was: gnl|Prokka|DFKDNBMG_99)

Region	Type	From	To	Most similar known cluster		Similarity
Region 41.1	phosphonate	110,450	135,483	polysaccharide B	Saccharide	10%

gnlProkkaDFKDNBMG_100 (original name was: gnl|Prokka|DFKDNBMG_100)

Region	Type	From	To	Most similar known cluster		Similarity
Region 42.1	RRE-containing	56,301	74,317

gnlProkkaDFKDNBMG_112 (original name was: gnl|Prokka|DFKDNBMG_112)

Region	Type	From	To	Most similar known cluster		Similarity
Region 52.1	resorcinol	1	30,355

gnlProkkaDFKDNBMG_147 (original name was: gnl|Prokka|DFKDNBMG_147)

Region	Type	From	To	Most similar known cluster		Similarity
Region 73.1	resorcinol	22,536	63,675

Region	Type	From	To	Most similar known cluster	Similarity
Region 2.1	NRPS	1	44,360
Region 41.1	phosphonate	110,450	135,483	polysaccharide B	Saccharide	10%
Region 42.1	RRE-containing	56,301	74,317
Region 52.1	resorcinol	1	30,355
Region 73.1	resorcinol	22,536	63,675

Compact view

gnlProkkaDFKDNBMG_5 - Region 1 - NRPS

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Location: 1 - 44,360 nt. (total: 44,360 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 44360:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg2_17

AMP-binding (8..447): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DYFGSGSLIK
Nearest Stachelhaus code(s):: Ala DMGGFGCLIK (50% 8Å match); Leu DYFTFGLIIK (41% 8Å match); Hpr DYQYCGHLIK (32% 8Å match)
Stachelhaus code match:: 60% (weak)

AMP-binding (1210..1629): X

nrpys: Tyr, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DMTNMGEVAK
Nearest Stachelhaus code(s):: Asn DMTKVGEVGK (56% 8Å match)
Stachelhaus code match:: 70% (weak)

gnlProkkaDFKDNBMG_99 - Region 1 - phosphonate

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Location: 110,450 - 135,483 nt. (total: 25,034 nt) Show pHMM detection rules used

phosphonate: (phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))

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core biosynthetic genes

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KnownClusterBlast

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

gnlProkkaDFKDNBMG_100 - Region 1 - RRE-containing

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Location: 56,301 - 74,317 nt. (total: 18,017 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

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regulatory genes

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resistance

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaDFKDNBMG_112 - Region 1 - resorcinol

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Location: 1 - 30,355 nt. (total: 30,355 nt) Show pHMM detection rules used

Region on contig edge.

resorcinol: DarB

Legend:

core biosynthetic genes

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Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

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gnlProkkaDFKDNBMG_147 - Region 1 - resorcinol

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Location: 22,536 - 63,675 nt. (total: 41,140 nt) Show pHMM detection rules used

resorcinol: DarB

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.