## Sun Jun 30 16:43:07 2024 ## emapper-2.1.12 ## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_018847095.1/GCA_018847095.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_018847095.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_018847095.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs JFBFHGED_00001 349741.Amuc_0002 4.37e-297 814.0 COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,2ITNP@203494|Verrucomicrobiae 203494|Verrucomicrobiae L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA - - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N JFBFHGED_00002 349741.Amuc_0003 1.22e-220 608.0 COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,2ITJ7@203494|Verrucomicrobiae 203494|Verrucomicrobiae V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 JFBFHGED_00003 349741.Amuc_0004 2.05e-182 508.0 COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,2IU5C@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_3 JFBFHGED_00004 349741.Amuc_0005 0.0 986.0 COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,2IU4Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae N ABC-type uncharacterized transport system - - - - - - - - - - - - ABC_transp_aux JFBFHGED_00005 349741.Amuc_0006 0.0 1312.0 2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia,2IUH5@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF4340) - - - - - - - - - - - - DUF4340 JFBFHGED_00006 349741.Amuc_0007 9.53e-169 473.0 COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae 203494|Verrucomicrobiae S NIF3 (NGG1p interacting factor 3) - - - - - - - - - - - - NIF3 JFBFHGED_00007 349741.Amuc_0008 5.44e-230 633.0 COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia,2ITZF@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Responsible for synthesis of pseudouridine from uracil - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 JFBFHGED_00010 349741.Amuc_0009 3.75e-266 730.0 COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,46U8V@74201|Verrucomicrobia,2ITT8@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Chorismate mutase type II - - 4.2.1.51,5.4.99.5 ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,CM_2,PDT JFBFHGED_00011 349741.Amuc_0010 0.0 1035.0 COG3669@1|root,COG3669@2|Bacteria,46V90@74201|Verrucomicrobia,2IVNR@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos JFBFHGED_00012 349741.Amuc_0011 0.0 1408.0 COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,2ITPR@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA - - 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 JFBFHGED_00013 349741.Amuc_0012 7.21e-136 385.0 COG0558@1|root,COG0558@2|Bacteria,46VZY@74201|Verrucomicrobia,2IUG1@203494|Verrucomicrobiae 203494|Verrucomicrobiae I CDP-alcohol phosphatidyltransferase - - 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf JFBFHGED_00014 349741.Amuc_0015 1.92e-248 688.0 COG0513@1|root,COG0513@2|Bacteria,46S5M@74201|Verrucomicrobia,2IU0Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae L helicase superfamily c-terminal domain - - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C JFBFHGED_00016 349741.Amuc_0017 0.0 977.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - - - - - - - - - - - GFO_IDH_MocA,TAT_signal JFBFHGED_00017 1236514.BAKL01000003_gene403 3.53e-152 431.0 COG0454@1|root,COG0456@2|Bacteria,4NHTJ@976|Bacteroidetes,2FQS3@200643|Bacteroidia,4ANNJ@815|Bacteroidaceae 976|Bacteroidetes K YoaP-like - - - - - - - - - - - - Acetyltransf_1,YoaP JFBFHGED_00018 349741.Amuc_1120 9.18e-260 747.0 COG1554@1|root,COG1554@2|Bacteria,46TM2@74201|Verrucomicrobia,2IV0H@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 65, N-terminal domain - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Glyco_hyd_65N_2 JFBFHGED_00019 349741.Amuc_0018 1.23e-257 708.0 COG1082@1|root,COG1082@2|Bacteria,46UXT@74201|Verrucomicrobia,2ITIF@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - - JFBFHGED_00020 349741.Amuc_0019 1.45e-167 475.0 COG2234@1|root,COG2234@2|Bacteria 2|Bacteria DZ aminopeptidase activity - - 3.4.11.10,3.4.11.6 ko:K19701 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M28 JFBFHGED_00021 349741.Amuc_0020 7.96e-250 689.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily ycaD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08219 - - - - ko00000,ko02000 2.A.1.26 - - MFS_1,Sugar_tr JFBFHGED_00022 349741.Amuc_0021 5.77e-283 779.0 COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia,2ITMX@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Sigma-54 factor, Activator interacting domain (AID) - - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD JFBFHGED_00023 349741.Amuc_0022 1.62e-161 453.0 COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia,2IUJA@203494|Verrucomicrobiae 203494|Verrucomicrobiae E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 JFBFHGED_00024 349741.Amuc_0024 3.57e-130 370.0 COG1971@1|root,COG1971@2|Bacteria 2|Bacteria P manganese ion transmembrane transporter activity mntP - - - - - - - - - - - Mntp JFBFHGED_00025 349741.Amuc_0025 0.0 1393.0 2DV5S@1|root,33U70@2|Bacteria,46XA4@74201|Verrucomicrobia,2IV64@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00026 349741.Amuc_0026 5.08e-265 729.0 2DYWX@1|root,34BHD@2|Bacteria,46X03@74201|Verrucomicrobia,2IW8K@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00027 349741.Amuc_0027 2.03e-309 845.0 COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia,2ITKR@203494|Verrucomicrobiae 203494|Verrucomicrobiae L MgsA AAA+ ATPase C terminal - - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N JFBFHGED_00029 349741.Amuc_0029 6.25e-217 599.0 COG0451@1|root,COG0451@2|Bacteria,46UCR@74201|Verrucomicrobia,2IWKH@203494|Verrucomicrobiae 203494|Verrucomicrobiae M NmrA-like family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase JFBFHGED_00030 349741.Amuc_0030 2.96e-266 728.0 COG2334@1|root,COG2334@2|Bacteria,46TIS@74201|Verrucomicrobia,2IVEV@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Phosphotransferase enzyme family - - - - - - - - - - - - APH JFBFHGED_00031 349741.Amuc_0031 1.72e-210 581.0 COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,2ITZR@203494|Verrucomicrobiae 203494|Verrucomicrobiae JM Nucleotidyl transferase - - - - - - - - - - - - NTP_transf_3,NTP_transferase JFBFHGED_00033 349741.Amuc_0033 7.33e-152 428.0 COG1994@1|root,COG1994@2|Bacteria,46VDN@74201|Verrucomicrobia,2IUVX@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Peptidase family M50 - - - - - - - - - - - - Peptidase_M50 JFBFHGED_00034 349741.Amuc_0034 0.0 1015.0 COG0442@1|root,COG0442@2|Bacteria,46SE3@74201|Verrucomicrobia,2ITKS@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Prolyl-tRNA synthetase, C-terminal proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b JFBFHGED_00040 349741.Amuc_0036 0.0 1533.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00043 349741.Amuc_0037 0.0 934.0 COG0531@1|root,COG0531@2|Bacteria 2|Bacteria E amino acid - - - ko:K20265 ko02024,map02024 - - - ko00000,ko00001,ko02000 2.A.3.7.1,2.A.3.7.3 - - AA_permease_2 JFBFHGED_00044 349741.Amuc_0038 2.53e-214 593.0 COG2066@1|root,COG2066@2|Bacteria,46SKT@74201|Verrucomicrobia,2IWMT@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Glutaminase - - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Glutaminase JFBFHGED_00045 349741.Amuc_0039 1.3e-81 243.0 COG0454@1|root,COG0454@2|Bacteria 2|Bacteria K -acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 JFBFHGED_00046 349741.Amuc_0040 1.16e-291 801.0 COG1115@1|root,COG1115@2|Bacteria,46TWQ@74201|Verrucomicrobia,2IU9Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Sodium:alanine symporter family - - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp JFBFHGED_00048 349741.Amuc_0041 2.56e-248 682.0 COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,2ITHW@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 JFBFHGED_00049 349741.Amuc_0042 2.05e-185 519.0 COG2890@1|root,COG2890@2|Bacteria,46SZE@74201|Verrucomicrobia,2IU5P@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC - 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS JFBFHGED_00050 349741.Amuc_0043 0.0 1397.0 COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia,2ITWU@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII JFBFHGED_00051 349741.Amuc_0044 2.49e-190 529.0 COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,2ITVJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF - 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase JFBFHGED_00055 349741.Amuc_0047 3.67e-153 431.0 COG0500@1|root,COG2226@2|Bacteria,46STX@74201|Verrucomicrobia,2IU7J@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q ubiE/COQ5 methyltransferase family menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran JFBFHGED_00056 349741.Amuc_0048 0.0 937.0 COG0534@1|root,COG0534@2|Bacteria,46Z02@74201|Verrucomicrobia,2IU41@203494|Verrucomicrobiae 203494|Verrucomicrobiae V MatE - - - - - - - - - - - - MatE JFBFHGED_00058 349741.Amuc_0760 3.38e-50 172.0 28IN0@1|root,2Z8NG@2|Bacteria,46W43@74201|Verrucomicrobia 74201|Verrucomicrobia S Glycosyltransferase family 10 (fucosyltransferase) C-term - - - - - - - - - - - - Glyco_transf_10 JFBFHGED_00060 349741.Amuc_0065 5.78e-166 481.0 COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia,2ITRE@203494|Verrucomicrobiae 203494|Verrucomicrobiae E HMGL-like - - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like JFBFHGED_00061 349741.Amuc_0051 0.0 1117.0 COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,2ITRD@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DHHA1 domain - - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 JFBFHGED_00062 349741.Amuc_0052 0.0 1810.0 COG3525@1|root,COG3525@2|Bacteria 2|Bacteria G beta-N-acetylhexosaminidase activity hyl GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 ko:K01197,ko:K15719 ko00531,ko01100,ko04931,map00531,map01100,map04931 M00076,M00077 R07824,R07825,R09672,R09673,R10905 RC00059,RC00397,RC00451,RC00746 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 - GH84 - F5_F8_type_C,Glyco_hydro_20b,NAGidase JFBFHGED_00063 240016.ABIZ01000001_gene653 1.73e-39 167.0 COG5373@1|root,COG5373@2|Bacteria,46S9T@74201|Verrucomicrobia,2IUWT@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Predicted membrane protein (DUF2339) - - - - - - - - - - - - DUF2339 JFBFHGED_00064 349741.Amuc_0053 1.46e-213 591.0 COG0803@1|root,COG0803@2|Bacteria,46T95@74201|Verrucomicrobia,2IU7E@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA JFBFHGED_00065 349741.Amuc_0054 8.53e-84 249.0 29760@1|root,2ZUDX@2|Bacteria,46WRV@74201|Verrucomicrobia,2IWIT@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00066 349741.Amuc_0055 9.69e-180 501.0 COG1121@1|root,COG1121@2|Bacteria,46T1P@74201|Verrucomicrobia,2ITV4@203494|Verrucomicrobiae 203494|Verrucomicrobiae P AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K09820 - M00243 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC_tran JFBFHGED_00067 349741.Amuc_0056 1.43e-175 493.0 COG1108@1|root,COG1108@2|Bacteria,46V67@74201|Verrucomicrobia,2IUB1@203494|Verrucomicrobiae 203494|Verrucomicrobiae P FecCD transport family - - - ko:K09819 - M00243 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 JFBFHGED_00068 349741.Amuc_0057 6.37e-125 355.0 COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia,2IUNQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S UvrB/uvrC motif - - - ko:K19411 - - - - ko00000 - - - UVR JFBFHGED_00069 349741.Amuc_0058 7.22e-240 660.0 COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,2ITP7@203494|Verrucomicrobiae 203494|Verrucomicrobiae E ATP:guanido phosphotransferase, C-terminal catalytic domain - - 2.7.14.1 ko:K19405 - - R11090 RC00002,RC00203 ko00000,ko01000 - - - ATP-gua_Ptrans JFBFHGED_00070 349741.Amuc_0059 0.0 1587.0 COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae 203494|Verrucomicrobiae O C-terminal, D2-small domain, of ClpB protein - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR JFBFHGED_00072 349741.Amuc_0063 3.96e-63 194.0 COG0607@1|root,COG0607@2|Bacteria,46X0H@74201|Verrucomicrobia,2IWDJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Rhodanese Homology Domain - - - ko:K03972 - - - - ko00000 - - - Rhodanese JFBFHGED_00073 349741.Amuc_0064 8.41e-192 533.0 COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,2IUC8@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase JFBFHGED_00074 349741.Amuc_0065 0.0 985.0 COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia,2ITRE@203494|Verrucomicrobiae 203494|Verrucomicrobiae E HMGL-like - - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like JFBFHGED_00075 349741.Amuc_0066 2.09e-213 590.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - SGL JFBFHGED_00076 349741.Amuc_0067 2.62e-87 259.0 COG1610@1|root,COG1610@2|Bacteria,46T4B@74201|Verrucomicrobia,2IUKM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Yqey-like protein - - - ko:K09117 - - - - ko00000 - - - YqeY JFBFHGED_00077 349741.Amuc_0068 4.98e-155 436.0 COG1211@1|root,COG1211@2|Bacteria,46T2A@74201|Verrucomicrobia,2IUDG@203494|Verrucomicrobiae 203494|Verrucomicrobiae I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD JFBFHGED_00078 349741.Amuc_0069 9.87e-180 503.0 COG0451@1|root,COG0451@2|Bacteria,46SWG@74201|Verrucomicrobia,2IUD4@203494|Verrucomicrobiae 203494|Verrucomicrobiae GM Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - - - - - - - - - - Epimerase,SKI JFBFHGED_00079 349741.Amuc_0070 3.01e-226 624.0 COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,2ITQN@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class I (W and Y) - - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b JFBFHGED_00080 349741.Amuc_0071 5.23e-102 296.0 COG0589@1|root,COG0589@2|Bacteria,46T47@74201|Verrucomicrobia,2IV0V@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Universal stress protein family - - - - - - - - - - - - Usp JFBFHGED_00081 349741.Amuc_0072 3.14e-185 515.0 COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia,2ITNG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S YmdB-like protein - - - ko:K09769 - - - - ko00000 - - - YmdB JFBFHGED_00083 349741.Amuc_0073 2.94e-168 472.0 COG1179@1|root,COG1179@2|Bacteria,46THP@74201|Verrucomicrobia,2IU4H@203494|Verrucomicrobiae 203494|Verrucomicrobiae H ThiF family - - - ko:K22132 - - - - ko00000,ko03016 - - - ThiF JFBFHGED_00084 349741.Amuc_0074 7.22e-114 327.0 296GV@1|root,2ZTSD@2|Bacteria,46WKD@74201|Verrucomicrobia,2IUJX@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00086 349741.Amuc_0075 1.35e-198 555.0 COG0524@1|root,COG0524@2|Bacteria,46XQ2@74201|Verrucomicrobia,2IWCQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae G pfkB family carbohydrate kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB JFBFHGED_00087 742817.HMPREF9449_01560 5.07e-238 667.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,2FP8Z@200643|Bacteroidia,231UK@171551|Porphyromonadaceae 976|Bacteroidetes G Mannitol dehydrogenase C-terminal domain uxuB - 1.1.1.17,1.1.1.67 ko:K00009,ko:K00045 ko00051,map00051 - R00868,R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C JFBFHGED_00088 742817.HMPREF9449_01561 6.29e-222 623.0 COG0738@1|root,COG0738@2|Bacteria,4NEYR@976|Bacteroidetes,2G2UG@200643|Bacteroidia,231YK@171551|Porphyromonadaceae 976|Bacteroidetes G Transporter gluP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 JFBFHGED_00091 349741.Amuc_0076 3.42e-114 328.0 COG1051@1|root,COG1051@2|Bacteria,46VKY@74201|Verrucomicrobia,2IUH7@203494|Verrucomicrobiae 203494|Verrucomicrobiae F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX JFBFHGED_00093 349741.Amuc_0077 3.32e-283 774.0 COG0156@1|root,COG0156@2|Bacteria,46SSH@74201|Verrucomicrobia,2ITW1@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class I and II kbl - 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_00094 349741.Amuc_0078 0.0 1682.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia,2IU0H@203494|Verrucomicrobiae 203494|Verrucomicrobiae KLT Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PEGA,Pkinase JFBFHGED_00095 349741.Amuc_0079 3.26e-177 494.0 COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,2IU01@203494|Verrucomicrobiae 203494|Verrucomicrobiae D AAA domain - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 JFBFHGED_00096 349741.Amuc_0080 0.0 1607.0 COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 JFBFHGED_00101 349741.Amuc_1996 3.27e-20 85.5 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - CHAP,DUF1906,PG_binding_1,Peptidase_M15_4 JFBFHGED_00105 349741.Amuc_0085 1.22e-44 145.0 COG2104@1|root,COG2104@2|Bacteria 2|Bacteria H thiamine diphosphate biosynthetic process thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - iJN678.ycf40 ThiS JFBFHGED_00106 349741.Amuc_0086 0.0 1048.0 COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia,2ITR4@203494|Verrucomicrobiae 203494|Verrucomicrobiae L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL - - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C JFBFHGED_00107 349741.Amuc_0088 0.0 1105.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - ko:K02847,ko:K13009,ko:K16705 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - PglL_A,Wzy_C,Wzy_C_2 JFBFHGED_00108 334413.FMG_1532 0.0 948.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,22H8G@1570339|Peptoniphilaceae 186801|Clostridia L type I restriction-modification system - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase JFBFHGED_00109 334413.FMG_1533 1.33e-48 177.0 COG0732@1|root,COG0732@2|Bacteria,1V66H@1239|Firmicutes,24BNF@186801|Clostridia,22IPF@1570339|Peptoniphilaceae 186801|Clostridia V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S JFBFHGED_00110 879309.HMPREF9199_0366 0.0 1589.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4H2IE@909932|Negativicutes 909932|Negativicutes L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - DUF3387,HSDR_N,ResIII JFBFHGED_00111 349741.Amuc_0089 1.06e-76 229.0 COG3189@1|root,COG3189@2|Bacteria,46WCK@74201|Verrucomicrobia 74201|Verrucomicrobia S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 JFBFHGED_00113 349741.Amuc_0090 7.69e-200 556.0 COG0181@1|root,COG0181@2|Bacteria,46SWD@74201|Verrucomicrobia,2IU65@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Porphobilinogen deaminase, dipyromethane cofactor binding domain - - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC JFBFHGED_00114 349741.Amuc_0091 1.41e-224 621.0 COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,2IU0T@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Glutamyl-tRNAGlu reductase, N-terminal domain hemA - 1.2.1.70 ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R04109 RC00055,RC00149 ko00000,ko00001,ko00002,ko01000 - - - GlutR_N,Shikimate_DH JFBFHGED_00115 349741.Amuc_0092 1.25e-163 459.0 COG4137@1|root,COG4137@2|Bacteria,46T0T@74201|Verrucomicrobia,2IUQ9@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Cytochrome C assembly protein - - - - - - - - - - - - Cytochrom_C_asm JFBFHGED_00116 349741.Amuc_0093 7.44e-187 519.0 COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia,2IU2Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Type I GTP cyclohydrolase folE2 folE2 - 3.5.4.16 ko:K09007 ko00790,ko01100,map00790,map01100 M00126 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GCHY-1 JFBFHGED_00117 349741.Amuc_0094 4.9e-49 156.0 COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia,2IUU2@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S18 - - - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 JFBFHGED_00118 349741.Amuc_0095 8.06e-33 113.0 COG0267@1|root,COG0267@2|Bacteria,46T91@74201|Verrucomicrobia,2IUS7@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L33 rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 JFBFHGED_00119 349741.Amuc_0096 9.77e-124 358.0 COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia,2IUEF@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Prokaryotic dksA/traR C4-type zinc finger - - - - - - - - - - - - zf-dskA_traR JFBFHGED_00120 349741.Amuc_0097 4.46e-227 625.0 COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia,2ITKM@203494|Verrucomicrobiae 203494|Verrucomicrobiae GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK JFBFHGED_00121 349741.Amuc_0098 6.68e-213 590.0 COG0144@1|root,COG0144@2|Bacteria 2|Bacteria J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun - 2.1.1.176,2.1.1.178 ko:K03500,ko:K11392 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,NusB JFBFHGED_00122 349741.Amuc_0099 6.07e-98 286.0 COG0622@1|root,COG0622@2|Bacteria,46XK7@74201|Verrucomicrobia,2IW4A@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 JFBFHGED_00123 349741.Amuc_0100 1.2e-79 238.0 COG1051@1|root,COG1051@2|Bacteria 2|Bacteria F GDP-mannose mannosyl hydrolase activity nudI - 3.6.1.55 ko:K03574,ko:K12944 - - - - ko00000,ko01000,ko03400 - - - NUDIX JFBFHGED_00125 349741.Amuc_0102 1.14e-266 738.0 COG0845@1|root,COG0845@2|Bacteria,46U5P@74201|Verrucomicrobia,2IU9K@203494|Verrucomicrobiae 203494|Verrucomicrobiae M HlyD family secretion protein - - - ko:K02005 - - - - ko00000 - - - HlyD_D23 JFBFHGED_00126 349741.Amuc_0103 3.38e-159 447.0 COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,2IUA4@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JFBFHGED_00127 349741.Amuc_0104 8.77e-300 821.0 COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,2IU74@203494|Verrucomicrobiae 203494|Verrucomicrobiae V MacB-like periplasmic core domain - - - - - - - - - - - - FtsX,MacB_PCD JFBFHGED_00128 349741.Amuc_0105 1.55e-296 813.0 COG1538@1|root,COG1538@2|Bacteria,46US3@74201|Verrucomicrobia,2IUAN@203494|Verrucomicrobiae 203494|Verrucomicrobiae MU Outer membrane efflux protein - - - - - - - - - - - - OEP JFBFHGED_00130 349741.Amuc_1143 0.0 1369.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00133 525373.HMPREF0766_12343 2.98e-47 155.0 2E5AU@1|root,3302Y@2|Bacteria,4P4ZP@976|Bacteroidetes 976|Bacteroidetes S Variant SH3 domain - - - - - - - - - - - - SH3_2 JFBFHGED_00134 349741.Amuc_0106 2.32e-259 712.0 COG1680@1|root,COG1680@2|Bacteria,46VB9@74201|Verrucomicrobia,2IWNM@203494|Verrucomicrobiae 203494|Verrucomicrobiae V Beta-lactamase - - - - - - - - - - - - Beta-lactamase JFBFHGED_00135 349741.Amuc_0110 8.86e-149 420.0 COG1720@1|root,COG1720@2|Bacteria,46VWT@74201|Verrucomicrobia,2IU7Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Uncharacterised protein family UPF0066 - - - - - - - - - - - - UPF0066 JFBFHGED_00136 349741.Amuc_0111 4.59e-289 791.0 COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia,2ITJU@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Dihydro-orotase-like - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 JFBFHGED_00137 349741.Amuc_0112 1.12e-217 601.0 COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia,2ITMZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N JFBFHGED_00138 349741.Amuc_0113 9.04e-118 337.0 COG2065@1|root,COG2065@2|Bacteria,46VY6@74201|Verrucomicrobia,2IUM6@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Phosphoribosyl transferase domain - - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran JFBFHGED_00139 349741.Amuc_0114 6.2e-89 261.0 COG0041@1|root,COG0041@2|Bacteria,46SRV@74201|Verrucomicrobia,2IUG9@203494|Verrucomicrobiae 203494|Verrucomicrobiae F AIR carboxylase - - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC JFBFHGED_00147 349741.Amuc_0116 0.0 966.0 COG2509@1|root,COG2509@2|Bacteria,46UJ1@74201|Verrucomicrobia,2ITVH@203494|Verrucomicrobiae 203494|Verrucomicrobiae H 5-formyltetrahydrofolate cyclo-ligase activity - - - ko:K07137 - - - - ko00000 - - - - JFBFHGED_00148 349741.Amuc_0117 3.8e-251 689.0 COG2957@1|root,COG2957@2|Bacteria,46SAM@74201|Verrucomicrobia,2IU1P@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Porphyromonas-type peptidyl-arginine deiminase - - 3.5.3.12 ko:K10536 ko00330,ko01100,map00330,map01100 - R01416 RC00177 ko00000,ko00001,ko01000 - - - PAD_porph JFBFHGED_00149 349741.Amuc_0118 2.03e-87 257.0 2E5IJ@1|root,3309Y@2|Bacteria,46YZF@74201|Verrucomicrobia,2IUSS@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00150 1173023.KE650771_gene3225 2.55e-27 120.0 COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1JI6M@1189|Stigonemataceae 1117|Cyanobacteria O SERine Proteinase INhibitors - - - ko:K13963 ko05146,map05146 - - - ko00000,ko00001 - - - Serpin JFBFHGED_00151 349741.Amuc_0119 7.82e-303 827.0 COG0750@1|root,COG0750@2|Bacteria 2|Bacteria M metalloendopeptidase activity rseP - 3.4.21.116 ko:K06399,ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ,PDZ_2,Peptidase_M50,Peptidase_S55 JFBFHGED_00152 349741.Amuc_0120 3.96e-270 744.0 COG0628@1|root,COG0628@2|Bacteria,46VTV@74201|Verrucomicrobia,2ITP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport JFBFHGED_00153 349741.Amuc_0121 0.0 1018.0 COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Domain of unknown function - - - - - - - - - - - - DUF4994,Sulfatase JFBFHGED_00155 909663.KI867150_gene300 1.18e-107 340.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MR4V@213462|Syntrophobacterales 28221|Deltaproteobacteria P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate JFBFHGED_00157 349741.Amuc_0127 1.02e-71 217.0 2A0RX@1|root,30MWM@2|Bacteria,46XN7@74201|Verrucomicrobia,2IW8P@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00158 349741.Amuc_0128 0.0 1280.0 COG0188@1|root,COG0188@2|Bacteria,46TWK@74201|Verrucomicrobia,2ITPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA Topoisomerase IV - - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_topoisoIV JFBFHGED_00160 349741.Amuc_0129 6.13e-106 308.0 COG3926@1|root,COG3926@2|Bacteria 2|Bacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3,Peptidase_M15_4 JFBFHGED_00163 349741.Amuc_0133 4.93e-189 527.0 COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae 203494|Verrucomicrobiae K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc JFBFHGED_00164 349741.Amuc_0134 7.04e-201 559.0 COG2234@1|root,COG2234@2|Bacteria,46VSB@74201|Verrucomicrobia,2IVUM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 JFBFHGED_00165 349741.Amuc_0135 0.0 1204.0 COG1361@1|root,COG1361@2|Bacteria,46TNR@74201|Verrucomicrobia,2IWKJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Aerotolerance regulator N-terminal - - - - - - - - - - - - BatA JFBFHGED_00166 349741.Amuc_0136 0.0 1329.0 COG2304@1|root,COG2373@1|root,COG5426@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG5426@2|Bacteria,46TJC@74201|Verrucomicrobia,2IWMG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Large extracellular alpha-helical protein - - - - - - - - - - - - - JFBFHGED_00169 349741.Amuc_0139 5.64e-229 631.0 COG0385@1|root,COG0385@2|Bacteria,46V81@74201|Verrucomicrobia,2IUMP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S SBF-like CPA transporter family (DUF4137) - - - ko:K14347 - - - - ko00000,ko02000,ko04147 2.A.93.1 - - SBF_like JFBFHGED_00170 349741.Amuc_0140 2.32e-266 731.0 COG0162@1|root,COG0162@2|Bacteria,46S76@74201|Verrucomicrobia,2IWM1@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class I (W and Y) - - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - tRNA-synt_1b JFBFHGED_00172 349741.Amuc_0142 3.25e-81 240.0 COG3169@1|root,COG3169@2|Bacteria,46T5W@74201|Verrucomicrobia,2IUI9@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Putative member of DMT superfamily (DUF486) - - - ko:K09922 - - - - ko00000 - - - DMT_6 JFBFHGED_00173 349741.Amuc_0143 8.13e-207 574.0 COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia,2ITN8@203494|Verrucomicrobiae 203494|Verrucomicrobiae EP N-terminal TM domain of oligopeptide transport permease C - - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N JFBFHGED_00174 349741.Amuc_0144 4.04e-211 584.0 COG0601@1|root,COG0601@2|Bacteria,46SJN@74201|Verrucomicrobia,2ITJ0@203494|Verrucomicrobiae 203494|Verrucomicrobiae EP Binding-protein-dependent transport system inner membrane component - - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 JFBFHGED_00175 349741.Amuc_0145 0.0 1197.0 COG4166@1|root,COG4166@2|Bacteria,46SBG@74201|Verrucomicrobia,2ITVI@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 JFBFHGED_00176 349741.Amuc_0146 0.0 1271.0 COG3669@1|root,COG3669@2|Bacteria 2|Bacteria G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,F5_F8_type_C JFBFHGED_00177 349741.Amuc_0147 8.32e-208 577.0 COG2143@1|root,COG2143@2|Bacteria,46Z6E@74201|Verrucomicrobia,2IW7D@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_7 JFBFHGED_00178 349741.Amuc_0148 1.1e-297 811.0 COG1748@1|root,COG1748@2|Bacteria,46U4S@74201|Verrucomicrobia,2ITQI@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Saccharopine dehydrogenase C-terminal domain - - 1.5.1.7 ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 M00030,M00032 R00715 RC00217,RC01532 ko00000,ko00001,ko00002,ko01000 - - - Sacchrp_dh_C,Sacchrp_dh_NADP JFBFHGED_00179 762968.HMPREF9441_02620 4.19e-50 161.0 COG2076@1|root,COG2076@2|Bacteria,4NT3T@976|Bacteroidetes,2FUAP@200643|Bacteroidia 976|Bacteroidetes P Small Multidrug Resistance protein emrE - - ko:K03297 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res JFBFHGED_00180 349741.Amuc_0149 6.82e-226 623.0 COG1409@1|root,COG1409@2|Bacteria 2|Bacteria S acid phosphatase activity - - - ko:K01128 - - - - ko00000,ko01000 - - - Metallophos JFBFHGED_00186 349741.Amuc_0152 2.79e-258 718.0 COG0206@1|root,COG0206@2|Bacteria,46UWD@74201|Verrucomicrobia,2ITWH@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Tubulin/FtsZ family, GTPase domain - - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin JFBFHGED_00187 349741.Amuc_0153 7.64e-291 794.0 COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia,2ITMT@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA JFBFHGED_00188 349741.Amuc_0154 1.78e-138 392.0 COG0791@1|root,COG0791@2|Bacteria,46VUJ@74201|Verrucomicrobia,2IUPC@203494|Verrucomicrobiae 203494|Verrucomicrobiae M NLP P60 protein - - - - - - - - - - - - - JFBFHGED_00189 349741.Amuc_0155 0.0 1233.0 COG1109@1|root,COG1109@2|Bacteria,46SB1@74201|Verrucomicrobia,2ITGG@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV JFBFHGED_00190 349741.Amuc_0156 0.0 1083.0 COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,2ITX3@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran JFBFHGED_00191 349741.Amuc_0157 0.0 1123.0 COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,2ITX3@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran JFBFHGED_00192 349741.Amuc_0158 2.83e-248 692.0 COG0388@1|root,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H NAD synthase - - - - - - - - - - - - CN_hydrolase,NAD_synthase JFBFHGED_00193 349741.Amuc_0159 2.81e-167 470.0 COG0767@1|root,COG0767@2|Bacteria,46VY4@74201|Verrucomicrobia,2IWMP@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE JFBFHGED_00194 349741.Amuc_0160 1.16e-178 499.0 COG1127@1|root,COG1127@2|Bacteria,46SRC@74201|Verrucomicrobia,2ITMB@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q ATPases associated with a variety of cellular activities - - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran JFBFHGED_00195 349741.Amuc_0161 4.2e-208 578.0 COG1463@1|root,COG1463@2|Bacteria,46T81@74201|Verrucomicrobia,2IUM4@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q MlaD protein - - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD JFBFHGED_00196 349741.Amuc_0162 2.43e-34 121.0 COG4575@1|root,COG4575@2|Bacteria 2|Bacteria T ribosome binding - - - - - - - - - - - - DUF883 JFBFHGED_00199 349741.Amuc_0165 4.02e-262 717.0 COG2805@1|root,COG2805@2|Bacteria,46UF2@74201|Verrucomicrobia,2ITJW@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE JFBFHGED_00200 349741.Amuc_0166 5.05e-258 707.0 COG2805@1|root,COG2805@2|Bacteria,46SY2@74201|Verrucomicrobia,2ITP5@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Type II/IV secretion system protein - - - ko:K02669 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE JFBFHGED_00201 349741.Amuc_0167 1.34e-222 617.0 COG0760@1|root,COG0760@2|Bacteria 2|Bacteria O peptidyl-prolyl cis-trans isomerase activity ppiD - 5.2.1.8 ko:K03769,ko:K03770,ko:K03771,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 JFBFHGED_00204 349741.Amuc_0168 8.76e-301 828.0 29ZA9@1|root,30M8M@2|Bacteria,46XI8@74201|Verrucomicrobia,2IVZI@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00205 349741.Amuc_0169 7.01e-164 460.0 COG1212@1|root,COG1212@2|Bacteria,46SS4@74201|Verrucomicrobia,2IU4F@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 JFBFHGED_00206 349741.Amuc_0170 0.0 1049.0 COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia,2ITX8@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase JFBFHGED_00207 349741.Amuc_0171 0.0 952.0 COG0591@1|root,COG0591@2|Bacteria,46SPP@74201|Verrucomicrobia,2ITZE@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Sodium:solute symporter family - - - - - - - - - - - - SSF JFBFHGED_00208 349741.Amuc_0172 0.0 1592.0 2F4ED@1|root,33X4P@2|Bacteria,46VJA@74201|Verrucomicrobia,2IUYK@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00209 349741.Amuc_0172 0.0 2486.0 2F4ED@1|root,33X4P@2|Bacteria,46VJA@74201|Verrucomicrobia,2IUYK@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00211 349741.Amuc_0175 9.99e-269 737.0 COG0265@1|root,COG0265@2|Bacteria,46ZCC@74201|Verrucomicrobia,2IUF5@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 JFBFHGED_00212 349741.Amuc_0176 2.31e-232 640.0 COG0265@1|root,COG0265@2|Bacteria,46ZF6@74201|Verrucomicrobia,2IU58@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Trypsin-like peptidase domain - - - - - - - - - - - - PDZ_2,Trypsin_2 JFBFHGED_00213 349741.Amuc_0177 0.0 1611.0 COG0744@1|root,COG0744@2|Bacteria,46U6K@74201|Verrucomicrobia,2ITYQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Transglycosylase - - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase JFBFHGED_00214 349741.Amuc_0178 4.51e-267 735.0 COG1322@1|root,COG1322@2|Bacteria,46THH@74201|Verrucomicrobia,2IUNZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S RmuC family - - - ko:K09760 - - - - ko00000 - - - RmuC JFBFHGED_00216 349741.Amuc_0179 8.07e-147 415.0 COG0546@1|root,COG0546@2|Bacteria,46WZP@74201|Verrucomicrobia,2IUMS@203494|Verrucomicrobiae 203494|Verrucomicrobiae S HAD-hyrolase-like - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 JFBFHGED_00217 349741.Amuc_0180 1.53e-126 366.0 COG1043@1|root,COG1043@2|Bacteria,46SD4@74201|Verrucomicrobia,2ITXD@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep JFBFHGED_00218 349741.Amuc_0181 1.17e-163 462.0 COG1714@1|root,COG1714@2|Bacteria,46ZIK@74201|Verrucomicrobia,2IV0N@203494|Verrucomicrobiae 203494|Verrucomicrobiae S RDD family - - - - - - - - - - - - RDD JFBFHGED_00219 349741.Amuc_0182 0.0 991.0 COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,2ITIK@203494|Verrucomicrobiae 203494|Verrucomicrobiae M MacB-like periplasmic core domain - - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD JFBFHGED_00220 349741.Amuc_0183 5.62e-159 451.0 COG2367@1|root,COG2367@2|Bacteria,46XT3@74201|Verrucomicrobia,2IWHY@203494|Verrucomicrobiae 203494|Verrucomicrobiae V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 JFBFHGED_00221 349741.Amuc_0184 1.21e-78 238.0 COG2839@1|root,COG2839@2|Bacteria,46WEX@74201|Verrucomicrobia,2IUVN@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF456) - - - ko:K09793 - - - - ko00000 - - - DUF456 JFBFHGED_00222 349741.Amuc_0185 1.92e-53 169.0 2DVAH@1|root,32UZ0@2|Bacteria 2|Bacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF3784,bPH_5 JFBFHGED_00223 349741.Amuc_0186 0.0 1459.0 COG1554@1|root,COG1554@2|Bacteria,46TM2@74201|Verrucomicrobia,2IV0H@203494|Verrucomicrobiae 2|Bacteria G Glycosyl hydrolase family 65, N-terminal domain - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m JFBFHGED_00224 349741.Amuc_0187 5.16e-231 639.0 COG2234@1|root,COG2234@2|Bacteria,46XPN@74201|Verrucomicrobia,2IWC0@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Peptidase family M28 - - - - - - - - - - - - Peptidase_M28 JFBFHGED_00225 349741.Amuc_0188 1.1e-187 530.0 COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia,2IUAQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 JFBFHGED_00226 349741.Amuc_0189 0.0 1778.0 COG0060@1|root,COG0060@2|Bacteria,46SEC@74201|Verrucomicrobia,2ITJZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS JFBFHGED_00227 349741.Amuc_0190 4.22e-169 474.0 COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,2IUIT@203494|Verrucomicrobiae 203494|Verrucomicrobiae MU Signal peptidase (SPase) II lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 JFBFHGED_00228 349741.Amuc_0191 1.74e-145 411.0 2EJX7@1|root,33DMV@2|Bacteria,46WSK@74201|Verrucomicrobia,2IUU7@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF1573) - - - - - - - - - - - - DUF1573 JFBFHGED_00229 349741.Amuc_0192 5.84e-110 316.0 COG0607@1|root,COG0607@2|Bacteria,46T32@74201|Verrucomicrobia,2IUWC@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Rhodanese-like domain - - - - - - - - - - - - Rhodanese JFBFHGED_00230 349741.Amuc_0193 1.54e-288 788.0 COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,2IU2B@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 JFBFHGED_00231 349741.Amuc_0194 0.0 1077.0 COG1075@1|root,COG1075@2|Bacteria,46Z7G@74201|Verrucomicrobia,2IU8E@203494|Verrucomicrobiae 203494|Verrucomicrobiae S acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - - - - - - - - - - - JFBFHGED_00235 349741.Amuc_0198 8.14e-75 224.0 COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia,2IUD1@203494|Verrucomicrobiae 203494|Verrucomicrobiae J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS - - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 JFBFHGED_00236 349741.Amuc_0199 0.0 925.0 COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia,2IU3T@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Tetratricopeptide repeat - - - - - - - - - - - - - JFBFHGED_00237 349741.Amuc_0200 4.47e-98 285.0 COG0346@1|root,COG0346@2|Bacteria,46VJH@74201|Verrucomicrobia,2IVW3@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Glyoxalase-like domain - - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 JFBFHGED_00238 349741.Amuc_0201 0.0 1018.0 COG4799@1|root,COG4799@2|Bacteria,46Z6F@74201|Verrucomicrobia,2IWPP@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Carboxyl transferase domain - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans JFBFHGED_00240 349741.Amuc_0203 4.29e-47 155.0 COG0511@1|root,COG0511@2|Bacteria,46VQF@74201|Verrucomicrobia 74201|Verrucomicrobia I PFAM biotin lipoyl attachment domain-containing protein - - - - - - - - - - - - Biotin_lipoyl JFBFHGED_00241 349741.Amuc_0204 0.0 960.0 COG1883@1|root,COG1883@2|Bacteria,46TTY@74201|Verrucomicrobia,2IVBT@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Na+-transporting oxaloacetate decarboxylase beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta JFBFHGED_00242 349741.Amuc_0205 8.97e-160 450.0 COG0340@1|root,COG0340@2|Bacteria,46SX6@74201|Verrucomicrobia,2IUHW@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Biotin/lipoate A/B protein ligase family - - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB JFBFHGED_00243 349741.Amuc_0206 0.0 968.0 COG0427@1|root,COG0427@2|Bacteria,46TQC@74201|Verrucomicrobia,2IUYA@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Acetyl-CoA hydrolase/transferase C-terminal domain - - - - - - - - - - - - AcetylCoA_hyd_C,AcetylCoA_hydro JFBFHGED_00245 349741.Amuc_0208 9.8e-199 551.0 COG1209@1|root,COG1209@2|Bacteria,46SHD@74201|Verrucomicrobia,2ITVA@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase JFBFHGED_00246 349741.Amuc_0209 1.76e-260 712.0 COG1088@1|root,COG1088@2|Bacteria,46S98@74201|Verrucomicrobia,2IU1G@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Male sterility protein - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd JFBFHGED_00247 349741.Amuc_0210 4.41e-226 623.0 COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,2ITK8@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Phosphofructokinase - - 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK JFBFHGED_00248 349741.Amuc_0211 2.7e-174 486.0 COG1573@1|root,COG1573@2|Bacteria,46UE4@74201|Verrucomicrobia,2ITSY@203494|Verrucomicrobiae 203494|Verrucomicrobiae L uracil-dna glycosylase - - - ko:K10800 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG JFBFHGED_00249 1002367.HMPREF0673_02839 1.15e-37 130.0 2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,2FU2H@200643|Bacteroidia 976|Bacteroidetes S tigr02436 - - - - - - - - - - - - 23S_rRNA_IVP JFBFHGED_00250 349741.Amuc_0213 0.0 939.0 COG0064@1|root,COG0064@2|Bacteria,46S5X@74201|Verrucomicrobia,2ITJA@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey JFBFHGED_00251 349741.Amuc_0214 0.0 1004.0 COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,2ITSM@203494|Verrucomicrobiae 2|Bacteria EH Thiamine pyrophosphate enzyme, central domain poxB - 1.2.3.3,1.2.5.1 ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 - R00207,R03145 RC00860,RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N JFBFHGED_00252 349741.Amuc_0216 0.0 1574.0 COG3345@1|root,COG3345@2|Bacteria,46XJC@74201|Verrucomicrobia,2IW2A@203494|Verrucomicrobiae 203494|Verrucomicrobiae G alpha-galactosidase - - - - - - - - - - - - - JFBFHGED_00254 349741.Amuc_0218 0.0 1721.0 COG0474@1|root,COG0474@2|Bacteria,46TTZ@74201|Verrucomicrobia,2IVBX@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase JFBFHGED_00255 349741.Amuc_0219 1.17e-252 697.0 COG0845@1|root,COG0845@2|Bacteria,46X9T@74201|Verrucomicrobia,2IVR2@203494|Verrucomicrobiae 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family mtrC - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 JFBFHGED_00256 349741.Amuc_0220 0.0 1919.0 COG0841@1|root,COG0841@2|Bacteria,46SDN@74201|Verrucomicrobia,2IWND@203494|Verrucomicrobiae 203494|Verrucomicrobiae V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran JFBFHGED_00257 349741.Amuc_0221 2.89e-308 843.0 COG0471@1|root,COG0471@2|Bacteria,46UPI@74201|Verrucomicrobia,2IU88@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Citrate transporter - - - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp JFBFHGED_00259 349741.Amuc_0223 1.24e-160 452.0 COG0351@1|root,COG0351@2|Bacteria,46SVN@74201|Verrucomicrobia,2IU7Q@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Phosphomethylpyrimidine kinase - - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin JFBFHGED_00261 349741.Amuc_0225 7.58e-135 394.0 COG0790@1|root,COG0790@2|Bacteria,46SWR@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM Sel1 domain protein repeat-containing protein - - - - - - - - - - - - Sel1 JFBFHGED_00265 1300350.DSW25_13965 0.00038 47.4 COG3152@1|root,COG3152@2|Bacteria,1RIHM@1224|Proteobacteria,2VC2B@28211|Alphaproteobacteria,3ZY55@60136|Sulfitobacter 28211|Alphaproteobacteria S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 JFBFHGED_00266 349741.Amuc_0228 0.0 1127.0 COG0827@1|root,COG0827@2|Bacteria 2|Bacteria L DNA restriction-modification system - - - - - - - - - - - - N6_Mtase,TaqI_C JFBFHGED_00269 349741.Amuc_0735 3e-40 164.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00275 349741.Amuc_0229 1.53e-112 323.0 2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia,2IUKV@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00277 349741.Amuc_0230 1.87e-158 447.0 COG1028@1|root,COG1028@2|Bacteria,46VVI@74201|Verrucomicrobia,2IVZ2@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 JFBFHGED_00279 349741.Amuc_0232 3.83e-93 276.0 COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia,2IUCF@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase JFBFHGED_00280 349741.Amuc_0233 1.38e-256 702.0 COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia,2ITX5@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Alcohol dehydrogenase GroES-like domain tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N JFBFHGED_00281 349741.Amuc_0235 0.0 1126.0 COG0058@1|root,COG0058@2|Bacteria,46TZP@74201|Verrucomicrobia,2IVFU@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Carbohydrate phosphorylase - - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase JFBFHGED_00282 349741.Amuc_0236 1.66e-168 472.0 COG0569@1|root,COG0569@2|Bacteria 2|Bacteria P domain protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2,TrkA_C JFBFHGED_00283 349741.Amuc_0237 2.04e-70 213.0 COG1393@1|root,COG1393@2|Bacteria,46VTP@74201|Verrucomicrobia,2IUPM@203494|Verrucomicrobiae 203494|Verrucomicrobiae P ArsC family - - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin JFBFHGED_00284 349741.Amuc_0238 0.0 938.0 COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia,2ITNR@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL JFBFHGED_00285 349741.Amuc_0240 6.19e-49 157.0 COG1826@1|root,COG1826@2|Bacteria,46WPX@74201|Verrucomicrobia,2IURB@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 JFBFHGED_00286 349741.Amuc_0241 8.04e-183 526.0 COG0790@1|root,COG0790@2|Bacteria,46SWR@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM Sel1 domain protein repeat-containing protein - - - - - - - - - - - - Sel1 JFBFHGED_00287 349741.Amuc_0242 7.5e-210 598.0 COG1187@1|root,COG1187@2|Bacteria,46SWQ@74201|Verrucomicrobia,2IUBZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J RNA pseudouridylate synthase - - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 JFBFHGED_00288 349741.Amuc_0243 2.05e-28 102.0 2BJR1@1|root,32E2W@2|Bacteria,46X8H@74201|Verrucomicrobia,2IV0B@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00289 349741.Amuc_0244 1.8e-161 453.0 COG0336@1|root,COG0336@2|Bacteria,46SS0@74201|Verrucomicrobia,2ITZV@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA (Guanine-1)-methyltransferase trmD - 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT JFBFHGED_00290 349741.Amuc_0245 1.7e-236 650.0 COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 JFBFHGED_00291 349741.Amuc_0246 4.4e-83 246.0 COG1321@1|root,COG1321@2|Bacteria 2|Bacteria K iron dependent repressor - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA JFBFHGED_00292 349741.Amuc_0247 0.0 1018.0 COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,46SFY@74201|Verrucomicrobia,2ITUF@203494|Verrucomicrobiae 203494|Verrucomicrobiae J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence - - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 JFBFHGED_00293 349741.Amuc_0248 3.96e-124 355.0 COG0778@1|root,COG0778@2|Bacteria,46WEH@74201|Verrucomicrobia 2|Bacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase JFBFHGED_00294 349741.Amuc_0249 2.28e-97 284.0 COG3153@1|root,COG3153@2|Bacteria,46X3J@74201|Verrucomicrobia,2IUET@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 JFBFHGED_00297 349741.Amuc_0253 6.34e-196 544.0 COG0739@1|root,COG0739@2|Bacteria,46X6I@74201|Verrucomicrobia,2IUPT@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 JFBFHGED_00298 349741.Amuc_0254 8.1e-210 581.0 COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia,2ITGF@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 JFBFHGED_00299 349741.Amuc_0255 3.2e-171 479.0 COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia,2IU4C@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf JFBFHGED_00300 349741.Amuc_0256 1.66e-115 331.0 COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,2IUKW@203494|Verrucomicrobiae 203494|Verrucomicrobiae H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) - - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK JFBFHGED_00301 349741.Amuc_0257 3.65e-169 473.0 COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia,2IU1I@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Dihydrodipicolinate reductase, N-terminus dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N JFBFHGED_00302 349741.Amuc_0258 1.28e-197 549.0 COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,2ITUK@203494|Verrucomicrobiae 203494|Verrucomicrobiae EM Dihydrodipicolinate synthetase family dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS JFBFHGED_00306 349741.Amuc_0260 0.0 1138.0 COG0526@1|root,COG4783@1|root,COG0526@2|Bacteria,COG4783@2|Bacteria,46X6Z@74201|Verrucomicrobia,2IUST@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,Redoxin JFBFHGED_00310 349741.Amuc_0263 1e-91 270.0 COG0319@1|root,COG0319@2|Bacteria,46WBN@74201|Verrucomicrobia,2IUS4@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 JFBFHGED_00311 349741.Amuc_0264 0.0 1058.0 COG1480@1|root,COG1480@2|Bacteria,46S4P@74201|Verrucomicrobia,2ITIA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S 7TM receptor with intracellular HD hydrolase - - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,HD JFBFHGED_00312 349741.Amuc_0265 1.07e-240 662.0 COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,2ITU1@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis JFBFHGED_00313 349741.Amuc_0266 2.73e-38 127.0 COG0333@1|root,COG0333@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p JFBFHGED_00314 349741.Amuc_0267 2.56e-110 317.0 COG1399@1|root,COG1399@2|Bacteria,46TBP@74201|Verrucomicrobia,2IURG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 JFBFHGED_00315 349741.Amuc_0268 3.08e-74 222.0 COG0537@1|root,COG0537@2|Bacteria,46SZ4@74201|Verrucomicrobia,2IUKK@203494|Verrucomicrobiae 203494|Verrucomicrobiae FG HIT domain - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT JFBFHGED_00316 349741.Amuc_0269 2.72e-222 616.0 COG0009@1|root,COG0009@2|Bacteria,46SUC@74201|Verrucomicrobia,2ITRQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC JFBFHGED_00317 349741.Amuc_0270 3.73e-111 321.0 COG0703@1|root,COG0703@2|Bacteria,46T2U@74201|Verrucomicrobia,2IUGN@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI JFBFHGED_00318 349741.Amuc_0271 9.56e-51 160.0 COG0228@1|root,COG0228@2|Bacteria,46WC2@74201|Verrucomicrobia,2IUP4@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S16 - - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 JFBFHGED_00319 1123261.AXDW01000007_gene2282 1.99e-14 76.6 COG1280@1|root,COG1280@2|Bacteria,1RD4I@1224|Proteobacteria,1S52N@1236|Gammaproteobacteria,1X70F@135614|Xanthomonadales 135614|Xanthomonadales E LysE type translocator - - - - - - - - - - - - LysE JFBFHGED_00320 349741.Amuc_0273 1.8e-196 546.0 COG4974@1|root,COG4974@2|Bacteria,46SQ4@74201|Verrucomicrobia,2ITUM@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Phage integrase, N-terminal SAM-like domain - - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase JFBFHGED_00321 349741.Amuc_0274 6.63e-146 417.0 COG5126@1|root,COG5126@2|Bacteria,46XN6@74201|Verrucomicrobia,2IW8M@203494|Verrucomicrobiae 203494|Verrucomicrobiae DTZ EF-hand, calcium binding motif - - - - - - - - - - - - EF-hand_5 JFBFHGED_00322 349741.Amuc_0275 3.14e-63 194.0 COG1862@1|root,COG1862@2|Bacteria,46T88@74201|Verrucomicrobia,2IUY8@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Preprotein translocase subunit - - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC JFBFHGED_00323 349741.Amuc_0276 1.68e-274 750.0 COG0343@1|root,COG0343@2|Bacteria,46TZR@74201|Verrucomicrobia,2ITG4@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT JFBFHGED_00324 349741.Amuc_0277 4.93e-141 398.0 COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia,2IUBK@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Putative methyltransferase trmB - 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 JFBFHGED_00325 349741.Amuc_0278 1.23e-164 461.0 COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,46SHC@74201|Verrucomicrobia,2IU63@203494|Verrucomicrobiae 203494|Verrucomicrobiae F NUDIX domain - - - - - - - - - - - - NUDIX JFBFHGED_00326 349741.Amuc_0279 7.22e-119 340.0 COG0797@1|root,COG0797@2|Bacteria,46WZB@74201|Verrucomicrobia,2IVVQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Lytic transglycolase - - - ko:K03642 - - - - ko00000 - - - DPBB_1 JFBFHGED_00327 349741.Amuc_0280 9.45e-182 509.0 COG1039@1|root,COG1039@2|Bacteria,46V1X@74201|Verrucomicrobia,2ITVX@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Ribonuclease HII - - 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII JFBFHGED_00328 349741.Amuc_0281 1.9e-62 191.0 COG0776@1|root,COG0776@2|Bacteria,46T4V@74201|Verrucomicrobia,2IUR0@203494|Verrucomicrobiae 203494|Verrucomicrobiae L bacterial (prokaryotic) histone like domain - - - - - - - - - - - - Bac_DNA_binding JFBFHGED_00335 349741.Amuc_0287 1.32e-138 393.0 COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,2IUER@203494|Verrucomicrobiae 203494|Verrucomicrobiae U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB JFBFHGED_00336 349741.Amuc_0288 1.15e-149 423.0 COG0382@1|root,COG0382@2|Bacteria 2|Bacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA JFBFHGED_00337 349741.Amuc_0289 1.45e-248 685.0 COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,2IUC6@203494|Verrucomicrobiae 203494|Verrucomicrobiae O SurA N-terminal domain - - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 JFBFHGED_00338 349741.Amuc_0290 0.0 1912.0 COG3250@1|root,COG3250@2|Bacteria,46U9M@74201|Verrucomicrobia,2IV89@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Domain of unknown function (DUF4982) - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N JFBFHGED_00339 349741.Amuc_0291 0.0 1742.0 COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia,2IU1F@203494|Verrucomicrobiae 203494|Verrucomicrobiae J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 JFBFHGED_00340 349741.Amuc_0292 5.79e-148 422.0 2AW3R@1|root,31MYP@2|Bacteria,46X7Q@74201|Verrucomicrobia,2IUWD@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - DUF4332 JFBFHGED_00341 349741.Amuc_0293 6.79e-79 234.0 COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,2IUB7@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN - - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 JFBFHGED_00342 349741.Amuc_0294 2.19e-56 175.0 COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,2IUPS@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ - - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 JFBFHGED_00343 349741.Amuc_0295 6.77e-34 117.0 COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia,2IUWM@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal L29 protein - - - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 JFBFHGED_00344 349741.Amuc_0296 1.98e-96 280.0 COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia,2IUCE@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs - - - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 JFBFHGED_00345 349741.Amuc_0297 4.27e-155 436.0 COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,2ITPJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC - - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C JFBFHGED_00346 349741.Amuc_0298 7.06e-70 211.0 COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia,2IUMZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome - - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 JFBFHGED_00347 349741.Amuc_0299 3.97e-143 406.0 2FI21@1|root,349UX@2|Bacteria,46W3I@74201|Verrucomicrobia,2IUIJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00348 349741.Amuc_0300 2.12e-58 180.0 COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,2IUPZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS - - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 JFBFHGED_00349 349741.Amuc_0301 1.85e-203 562.0 COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,2ITK3@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB - - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C JFBFHGED_00350 349741.Amuc_0302 8.4e-56 174.0 COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia,2IUPY@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW - - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 JFBFHGED_00351 349741.Amuc_0303 2.48e-127 363.0 COG0088@1|root,COG0088@2|Bacteria,46SWJ@74201|Verrucomicrobia,2IU4A@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L4/L1 family rplD - - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 JFBFHGED_00352 349741.Amuc_0304 3.86e-149 419.0 COG0087@1|root,COG0087@2|Bacteria,46SQV@74201|Verrucomicrobia,2IU4D@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 JFBFHGED_00353 349741.Amuc_0305 1.23e-63 194.0 COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia,2IUCB@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S10p/S20e - - - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 JFBFHGED_00354 349741.Amuc_0306 0.0 1389.0 COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,2ITYS@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome - - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 JFBFHGED_00355 349741.Amuc_0307 5.87e-104 301.0 COG0049@1|root,COG0049@2|Bacteria,46V3W@74201|Verrucomicrobia,2IU3Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S7p/S5e - - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 JFBFHGED_00356 349741.Amuc_0308 4.22e-57 178.0 COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,2IU8K@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S12/S23 - - - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 JFBFHGED_00360 349741.Amuc_0309 0.0 1009.0 COG0696@1|root,COG0696@2|Bacteria,46U4C@74201|Verrucomicrobia,2ITXW@203494|Verrucomicrobiae 203494|Verrucomicrobiae G BPG-independent PGAM N-terminus (iPGM_N) gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,iPGM_N JFBFHGED_00361 349741.Amuc_0310 6.05e-91 266.0 COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia,2IUVD@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Thioesterase superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT JFBFHGED_00362 349741.Amuc_0311 5.94e-262 719.0 COG3852@1|root,COG3852@2|Bacteria,46Z4V@74201|Verrucomicrobia,2ITPC@203494|Verrucomicrobiae 203494|Verrucomicrobiae T PAS domain - - - - - - - - - - - - HATPase_c,HisKA,PAS JFBFHGED_00363 349741.Amuc_0312 1.78e-300 823.0 COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Bacterial regulatory protein, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat JFBFHGED_00364 349741.Amuc_0313 0.0 1103.0 COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia,2IU5E@203494|Verrucomicrobiae 203494|Verrucomicrobiae O C-terminal four TMM region of protein-O-mannosyltransferase - - - - - - - - - - - - - JFBFHGED_00365 349741.Amuc_0314 2.09e-50 160.0 COG1722@1|root,COG1722@2|Bacteria 2|Bacteria L exodeoxyribonuclease VII activity xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S JFBFHGED_00366 349741.Amuc_0315 0.0 1210.0 COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,2ITIS@203494|Verrucomicrobiae 203494|Verrucomicrobiae HI Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C JFBFHGED_00367 349741.Amuc_0316 1.84e-163 459.0 COG0457@1|root,COG0457@2|Bacteria,46X6U@74201|Verrucomicrobia,2IUS6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Tetratricopeptide repeat - - - - - - - - - - - - - JFBFHGED_00368 349741.Amuc_0317 3.4e-120 343.0 COG1381@1|root,COG1381@2|Bacteria,46VUW@74201|Verrucomicrobia,2IUNX@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Recombination protein O N terminal - - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N JFBFHGED_00369 349741.Amuc_0318 1.35e-241 666.0 COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,2IUBP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Predicted permease YjgP/YjgQ family - - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ JFBFHGED_00370 349741.Amuc_0319 0.0 870.0 COG1160@1|root,COG1160@2|Bacteria,46SJY@74201|Verrucomicrobia,2ITU6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S KH-domain-like of EngA bacterial GTPase enzymes, C-terminal der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 JFBFHGED_00371 349741.Amuc_0320 1.23e-224 620.0 COG0444@1|root,COG0444@2|Bacteria,46U0J@74201|Verrucomicrobia,2ITGK@203494|Verrucomicrobiae 203494|Verrucomicrobiae EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY JFBFHGED_00372 517417.Cpar_0456 2.34e-41 146.0 COG0551@1|root,COG0551@2|Bacteria,1FF54@1090|Chlorobi 1090|Chlorobi L 23S rRNA-intervening sequence protein - - - - - - - - - - - - - JFBFHGED_00373 349741.Amuc_0333 4.42e-134 381.0 COG4845@1|root,COG4845@2|Bacteria 2|Bacteria V Chloramphenicol acetyltransferase cat - 2.3.1.28 ko:K19271 - - - - br01600,ko00000,ko01000,ko01504 - - - CAT JFBFHGED_00376 349741.Amuc_0334 0.0 1709.0 COG0577@1|root,COG0577@2|Bacteria,46XDE@74201|Verrucomicrobia,2IVIV@203494|Verrucomicrobiae 203494|Verrucomicrobiae V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD JFBFHGED_00377 349741.Amuc_0335 3.3e-157 443.0 COG1136@1|root,COG1136@2|Bacteria,46X0J@74201|Verrucomicrobia,2IVS0@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JFBFHGED_00378 349741.Amuc_0336 0.0 1456.0 COG4774@1|root,COG4774@2|Bacteria,46Z6G@74201|Verrucomicrobia,2IWPQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae P TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec JFBFHGED_00379 349741.Amuc_0337 1.31e-191 534.0 COG0287@1|root,COG0287@2|Bacteria,46SSN@74201|Verrucomicrobia,2IU8S@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH JFBFHGED_00381 349741.Amuc_0339 0.0 1706.0 COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,46VGN@74201|Verrucomicrobia,2ITZY@203494|Verrucomicrobiae 203494|Verrucomicrobiae EGIP Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase,MFS_1 JFBFHGED_00382 349741.Amuc_0340 1.57e-96 281.0 COG2131@1|root,COG2131@2|Bacteria,46WJA@74201|Verrucomicrobia,2IUDA@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Cytidine and deoxycytidylate deaminase zinc-binding region - - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 JFBFHGED_00384 349741.Amuc_0342 2.44e-90 265.0 COG1765@1|root,COG1765@2|Bacteria,46T1Y@74201|Verrucomicrobia,2IUE7@203494|Verrucomicrobiae 203494|Verrucomicrobiae O OsmC-like protein - - - - - - - - - - - - OsmC JFBFHGED_00385 349741.Amuc_0343 1.85e-211 608.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,2ITNE@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Disulphide bond corrector protein DsbC - - - - - - - - - - - - DsbC,Thioredoxin_7 JFBFHGED_00386 349741.Amuc_0343 2.47e-250 705.0 COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,2ITNE@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Disulphide bond corrector protein DsbC - - - - - - - - - - - - DsbC,Thioredoxin_7 JFBFHGED_00387 349741.Amuc_0344 1.75e-135 388.0 COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia,2IUJA@203494|Verrucomicrobiae 203494|Verrucomicrobiae E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 JFBFHGED_00388 349741.Amuc_0345 4.11e-119 342.0 COG0847@1|root,COG0847@2|Bacteria,46X72@74201|Verrucomicrobia,2IUEP@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Exonuclease - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T JFBFHGED_00389 349741.Amuc_0346 0.0 1538.0 COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia,2ITUY@203494|Verrucomicrobiae 203494|Verrucomicrobiae L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V JFBFHGED_00390 349741.Amuc_0347 1.11e-77 231.0 COG0799@1|root,COG0799@2|Bacteria,46T8H@74201|Verrucomicrobia,2IUTW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS JFBFHGED_00391 349741.Amuc_0348 0.0 1481.0 COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,Peptidase_M41 JFBFHGED_00393 349741.Amuc_0350 9.31e-251 689.0 COG1106@1|root,COG1106@2|Bacteria 2|Bacteria S AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - AAA_15,AAA_21 JFBFHGED_00394 349741.Amuc_0351 5.7e-196 543.0 COG0447@1|root,COG0447@2|Bacteria,46Z3Z@74201|Verrucomicrobia,2ITPX@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Enoyl-CoA hydratase/isomerase menB - 4.1.3.36 ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R07263 RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 JFBFHGED_00397 349741.Amuc_0354 5.88e-212 595.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP JFBFHGED_00401 349741.Amuc_0358 6.75e-129 368.0 COG1136@1|root,COG1136@2|Bacteria,46XHT@74201|Verrucomicrobia,2IVYF@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran JFBFHGED_00404 349741.Amuc_0361 0.0 2194.0 COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,46TJ4@74201|Verrucomicrobia,2ITSH@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran JFBFHGED_00405 349741.Amuc_0362 3.42e-97 282.0 2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00406 349741.Amuc_0363 1.1e-176 495.0 COG0300@1|root,COG0300@2|Bacteria,46V6A@74201|Verrucomicrobia,2IUAY@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Enoyl-(Acyl carrier protein) reductase - - - ko:K07124 - - - - ko00000 - - - adh_short JFBFHGED_00407 349741.Amuc_0364 5.53e-316 868.0 2EYYY@1|root,33S5Q@2|Bacteria,46UHA@74201|Verrucomicrobia,2ITNH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Fungal chitosanase of glycosyl hydrolase group 75 - - - - - - - - - - - - Glyco_hydro_75 JFBFHGED_00408 349741.Amuc_0365 5.5e-190 530.0 COG1562@1|root,COG1562@2|Bacteria,46VIE@74201|Verrucomicrobia,2IUH8@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Squalene/phytoene synthase - - 2.5.1.21 ko:K00801 ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130 - R00702,R02872,R06223 RC00362,RC00796,RC02839 ko00000,ko00001,ko01000,ko01006 - - - SQS_PSY JFBFHGED_00409 349741.Amuc_0366 0.0 958.0 COG3604@1|root,COG3604@2|Bacteria,46YU4@74201|Verrucomicrobia,2IVAR@203494|Verrucomicrobiae 203494|Verrucomicrobiae KT Bacterial regulatory protein, Fis family - - - ko:K02584 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - HTH_8,Sigma54_activat JFBFHGED_00410 349741.Amuc_0367 0.0 1059.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia,2IU71@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - CBS,Voltage_CLC JFBFHGED_00412 349741.Amuc_1996 3.92e-71 221.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - CHAP,DUF1906,PG_binding_1,Peptidase_M15_4 JFBFHGED_00414 349741.Amuc_0369 0.0 1154.0 COG3525@1|root,COG3525@2|Bacteria,46ZK1@74201|Verrucomicrobia,2IVDU@203494|Verrucomicrobiae 2|Bacteria G PFAM Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_00416 349741.Amuc_0371 0.0 1582.0 COG3292@1|root,COG3292@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Baseplate_J,CHB_HEX_C_1,Cu_amine_oxidN1,F5_F8_type_C,His_kinase,Reg_prop,Reprolysin_5,Sortilin-Vps10,VCBS,Y_Y_Y JFBFHGED_00419 349741.Amuc_0371 0.0 1280.0 COG3292@1|root,COG3292@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Baseplate_J,CHB_HEX_C_1,Cu_amine_oxidN1,F5_F8_type_C,His_kinase,Reg_prop,Reprolysin_5,Sortilin-Vps10,VCBS,Y_Y_Y JFBFHGED_00420 349741.Amuc_1253 0.0 2820.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46U9T@74201|Verrucomicrobia,2IWM5@203494|Verrucomicrobiae 203494|Verrucomicrobiae E GXGXG motif - - 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase JFBFHGED_00421 349741.Amuc_1252 0.0 1363.0 COG3968@1|root,COG3968@2|Bacteria 2|Bacteria S glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C JFBFHGED_00422 349741.Amuc_1251 0.0 2044.0 COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae 203494|Verrucomicrobiae EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain - - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS JFBFHGED_00423 349741.Amuc_1250 9.42e-258 707.0 COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,2ITTA@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Carbamoyl-phosphate synthase small chain, CPSase domain carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase JFBFHGED_00424 349741.Amuc_1249 4.15e-257 704.0 COG1089@1|root,COG1089@2|Bacteria,46SH0@74201|Verrucomicrobia,2ITUC@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose - - 4.2.1.47 ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R00888 RC00402 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd JFBFHGED_00425 349741.Amuc_1248 4.07e-247 680.0 COG0451@1|root,COG0451@2|Bacteria,46SD9@74201|Verrucomicrobia,2ITY4@203494|Verrucomicrobiae 203494|Verrucomicrobiae GM Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction fcl - 1.1.1.271 ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 - R05692 RC01014 ko00000,ko00001,ko01000 - - - Epimerase JFBFHGED_00426 349741.Amuc_1247 6.51e-277 762.0 COG1757@1|root,COG1757@2|Bacteria,46XTJ@74201|Verrucomicrobia,2IWIX@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Na+/H+ antiporter family - - - - - - - - - - - - Na_H_antiporter JFBFHGED_00427 349741.Amuc_1246 4.2e-269 740.0 2BHNH@1|root,32BRD@2|Bacteria,46Z4Q@74201|Verrucomicrobia,2IUDY@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00428 349741.Amuc_1245 9.48e-204 566.0 COG1482@1|root,COG1482@2|Bacteria,46SVM@74201|Verrucomicrobia,2IU31@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Phosphomannose isomerase type I - - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - - PMI_typeI JFBFHGED_00429 349741.Amuc_1244 1.02e-178 497.0 COG5632@1|root,COG5632@2|Bacteria,46VKP@74201|Verrucomicrobia,2IU5K@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 JFBFHGED_00430 349741.Amuc_0372 0.0 942.0 COG0076@1|root,COG0076@2|Bacteria,46TV2@74201|Verrucomicrobia 74201|Verrucomicrobia E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.15 ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 M00027 R00261,R00489,R01682,R02466 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Pyridoxal_deC JFBFHGED_00431 349741.Amuc_0892 2.36e-97 337.0 COG4625@1|root,COG4625@2|Bacteria,46WH4@74201|Verrucomicrobia 74201|Verrucomicrobia S pathogenesis - - - - - - - - - - - - - JFBFHGED_00432 349741.Amuc_0373 1.06e-115 333.0 COG1670@1|root,COG1670@2|Bacteria,46X7U@74201|Verrucomicrobia,2IUXM@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 JFBFHGED_00433 349741.Amuc_0374 0.0 2297.0 COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,2ITPP@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA polymerase alpha chain like domain - - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon JFBFHGED_00434 349741.Amuc_0375 4.66e-226 625.0 COG0167@1|root,COG0167@2|Bacteria,46S5W@74201|Verrucomicrobia,2IU2W@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Dihydroorotate dehydrogenase pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh JFBFHGED_00435 349741.Amuc_0376 3.19e-129 369.0 COG0352@1|root,COG0352@2|Bacteria,46T6K@74201|Verrucomicrobia,2IUF9@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Thiamine monophosphate synthase - - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI JFBFHGED_00436 349741.Amuc_0377 1.78e-140 399.0 COG1309@1|root,COG1309@2|Bacteria,46X7B@74201|Verrucomicrobia,2IUUJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N JFBFHGED_00437 349741.Amuc_0378 1.9e-149 422.0 COG0526@1|root,COG0526@2|Bacteria,46X0G@74201|Verrucomicrobia,2IWD9@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Thioredoxin-like - - - - - - - - - - - - Thioredoxin_8 JFBFHGED_00438 349741.Amuc_0379 0.0 1485.0 COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,46UPB@74201|Verrucomicrobia,2IV7Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,Paired_CXXCH_1 JFBFHGED_00439 349741.Amuc_0380 1.69e-295 809.0 COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae 74201|Verrucomicrobia S PFAM CBS domain containing protein - - - - - - - - - - - - CBS,DUF21 JFBFHGED_00440 349741.Amuc_0381 1.01e-293 805.0 COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae 2|Bacteria S PFAM CBS domain containing protein tlyC - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 JFBFHGED_00441 661367.LLO_3305 3.24e-17 90.5 COG1363@1|root,COG1363@2|Bacteria,1MXEU@1224|Proteobacteria,1RYRZ@1236|Gammaproteobacteria,1JDNY@118969|Legionellales 118969|Legionellales G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 JFBFHGED_00442 349741.Amuc_0382 0.0 1326.0 COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia,2ITWE@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 JFBFHGED_00443 187272.Mlg_1407 5.17e-76 253.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1WWCX@135613|Chromatiales 135613|Chromatiales MU PFAM Outer membrane efflux protein - - - - - - - - - - - - OEP JFBFHGED_00444 1123247.AUIJ01000007_gene2832 2.69e-17 93.2 COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 JFBFHGED_00445 1408428.JNJP01000025_gene256 1.24e-88 276.0 COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42RGM@68525|delta/epsilon subdivisions,2WW6I@28221|Deltaproteobacteria,2MGB7@213115|Desulfovibrionales 28221|Deltaproteobacteria V Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_D23 JFBFHGED_00446 335543.Sfum_3459 1.24e-07 58.9 COG1309@1|root,COG1309@2|Bacteria,1Q299@1224|Proteobacteria,42UP4@68525|delta/epsilon subdivisions,2WQF0@28221|Deltaproteobacteria,2MS2K@213462|Syntrophobacterales 28221|Deltaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N JFBFHGED_00447 349741.Amuc_0383 3.52e-48 154.0 COG0184@1|root,COG0184@2|Bacteria,46T87@74201|Verrucomicrobia,2IUVZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal_S15 rpsO - - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 JFBFHGED_00448 349741.Amuc_0384 1.37e-118 342.0 COG0110@1|root,COG0110@2|Bacteria,46TEB@74201|Verrucomicrobia,2IUHQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Mac JFBFHGED_00449 349741.Amuc_0385 7.5e-185 516.0 COG1376@1|root,COG1376@2|Bacteria 2|Bacteria D ErfK ybiS ycfS ynhG family protein - - - ko:K19234,ko:K19236 ko01503,map01503 - - - ko00000,ko00001,ko01002,ko01011 - - - YkuD JFBFHGED_00450 349741.Amuc_0386 0.0 1050.0 COG4626@1|root,COG4626@2|Bacteria,46ZJ1@74201|Verrucomicrobia,2IV51@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Terminase - - - - - - - - - - - - - JFBFHGED_00453 349741.Amuc_0389 4.53e-172 482.0 COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,2IU7R@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs - - 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 JFBFHGED_00454 349741.Amuc_0390 1.11e-125 358.0 COG1057@1|root,COG1057@2|Bacteria,46YSF@74201|Verrucomicrobia,2IUSZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like JFBFHGED_00455 349741.Amuc_0391 9.09e-164 457.0 COG0739@1|root,COG0739@2|Bacteria,46VAI@74201|Verrucomicrobia,2IU93@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 JFBFHGED_00456 349741.Amuc_0392 0.0 1384.0 COG3669@1|root,COG3669@2|Bacteria,46TW6@74201|Verrucomicrobia 74201|Verrucomicrobia G PFAM coagulation factor 5 8 type domain protein - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,F5_F8_type_C JFBFHGED_00458 349741.Amuc_0394 2.11e-171 479.0 COG4968@1|root,COG4968@2|Bacteria,46X8E@74201|Verrucomicrobia,2IUZZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Prepilin-type N-terminal cleavage methylation domain - - - - - - - - - - - - N_methyl JFBFHGED_00459 349741.Amuc_0395 6.38e-172 482.0 COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,2ITNM@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph - 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C JFBFHGED_00460 349741.Amuc_0396 0.0 891.0 COG1524@1|root,COG1524@2|Bacteria,46UZ5@74201|Verrucomicrobia,2ITHB@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest JFBFHGED_00461 349741.Amuc_0397 0.0 1320.0 COG3525@1|root,COG3525@2|Bacteria 2|Bacteria G beta-N-acetylhexosaminidase activity - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_00462 349741.Amuc_0398 5.42e-141 399.0 COG0132@1|root,COG0132@2|Bacteria,46VJB@74201|Verrucomicrobia,2IUDQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H AAA domain - - 6.3.3.3 ko:K01935 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03182 RC00868 ko00000,ko00001,ko00002,ko01000 - - - AAA_26 JFBFHGED_00464 349741.Amuc_0400 6.6e-178 498.0 COG1624@1|root,COG1624@2|Bacteria,46SSQ@74201|Verrucomicrobia,2IU56@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DisA bacterial checkpoint controller nucleotide-binding - - - - - - - - - - - - DisA_N JFBFHGED_00466 335543.Sfum_3011 1.56e-83 262.0 COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,2MR3S@213462|Syntrophobacterales 28221|Deltaproteobacteria S PFAM peptidase M28 - - - - - - - - - - - - Peptidase_M28 JFBFHGED_00467 349741.Amuc_0403 3.54e-148 417.0 COG1136@1|root,COG1136@2|Bacteria,46UQZ@74201|Verrucomicrobia,2IU5Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JFBFHGED_00468 349741.Amuc_0404 7.92e-186 518.0 COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,2ITKC@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase JFBFHGED_00469 349741.Amuc_0405 1.11e-115 334.0 COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia,2IUS2@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Outer membrane protein (OmpH-like) - - - ko:K06142 - - - - ko00000 - - - OmpH JFBFHGED_00470 349741.Amuc_0406 8.08e-174 493.0 COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia,2ITQF@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,LpxD JFBFHGED_00471 349741.Amuc_0407 2.5e-189 525.0 COG0600@1|root,COG0600@2|Bacteria,46TJF@74201|Verrucomicrobia,2IU1M@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 JFBFHGED_00472 349741.Amuc_0408 2.67e-179 500.0 COG1116@1|root,COG1116@2|Bacteria,46TJD@74201|Verrucomicrobia,2ITUG@203494|Verrucomicrobiae 203494|Verrucomicrobiae P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran JFBFHGED_00473 349741.Amuc_0409 1.29e-236 652.0 COG0715@1|root,COG0715@2|Bacteria,46WUQ@74201|Verrucomicrobia,2IV5U@203494|Verrucomicrobiae 203494|Verrucomicrobiae P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1_2 JFBFHGED_00475 349741.Amuc_0052 1.4e-225 672.0 COG3525@1|root,COG3525@2|Bacteria 2|Bacteria G beta-N-acetylhexosaminidase activity hyl GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 ko:K01197,ko:K15719 ko00531,ko01100,ko04931,map00531,map01100,map04931 M00076,M00077 R07824,R07825,R09672,R09673,R10905 RC00059,RC00397,RC00451,RC00746 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 - GH84 - F5_F8_type_C,Glyco_hydro_20b,NAGidase JFBFHGED_00477 349741.Amuc_0413 5.47e-103 299.0 COG0241@1|root,COG0241@2|Bacteria,46T3Q@74201|Verrucomicrobia,2IW66@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Polynucleotide kinase 3 phosphatase - - 3.1.3.82,3.1.3.83 ko:K03273 ko00540,ko01100,map00540,map01100 M00064 R05647,R09771 RC00017 ko00000,ko00001,ko00002,ko01000,ko01005 - - - HAD_2,Hydrolase_like JFBFHGED_00478 349741.Amuc_0414 1.11e-119 343.0 COG0279@1|root,COG0279@2|Bacteria,46SXU@74201|Verrucomicrobia,2IUZI@203494|Verrucomicrobiae 203494|Verrucomicrobiae G SIS domain - - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 JFBFHGED_00479 349741.Amuc_0415 0.0 912.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,46T1J@74201|Verrucomicrobia,2IVXQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M pfkB family carbohydrate kinase - - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - PfkB JFBFHGED_00480 349741.Amuc_0416 7.18e-43 140.0 COG0828@1|root,COG0828@2|Bacteria,46WP6@74201|Verrucomicrobia,2IWJ9@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S21 - - - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 JFBFHGED_00481 349741.Amuc_0417 2.43e-301 822.0 COG0001@1|root,COG0001@2|Bacteria,46S67@74201|Verrucomicrobia,2ITGJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Aminotransferase class-III hemL - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 JFBFHGED_00482 349741.Amuc_0418 1.18e-232 642.0 COG0666@1|root,COG0666@2|Bacteria,46XNF@74201|Verrucomicrobia,2IW95@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ankyrin repeats - - - - - - - - - - - - - JFBFHGED_00483 349741.Amuc_0419 0.0 1224.0 COG0477@1|root,COG2814@2|Bacteria,46TKN@74201|Verrucomicrobia,2IU9N@203494|Verrucomicrobiae 203494|Verrucomicrobiae EGP Sugar (and other) transporter - - - - - - - - - - - - Sugar_tr JFBFHGED_00484 349741.Amuc_0420 0.0 893.0 2A4XA@1|root,30TJ4@2|Bacteria,46X7N@74201|Verrucomicrobia,2IUVT@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00485 349741.Amuc_0421 0.0 1117.0 COG0008@1|root,COG0008@2|Bacteria,46S4X@74201|Verrucomicrobia,2ITW6@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class I (E and Q), anti-codon binding domain glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C JFBFHGED_00486 349741.Amuc_0422 6.93e-281 768.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia,2ITV0@203494|Verrucomicrobiae 203494|Verrucomicrobiae H GTP cyclohydrolase II - - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 JFBFHGED_00487 349741.Amuc_0423 5.54e-100 291.0 COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,2IUDV@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH - 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase JFBFHGED_00488 349741.Amuc_0424 2.22e-181 508.0 COG0781@1|root,COG0781@2|Bacteria,46T7V@74201|Verrucomicrobia,2IUM8@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB JFBFHGED_00489 349741.Amuc_0425 1.27e-187 523.0 COG0552@1|root,COG0552@2|Bacteria,46SKC@74201|Verrucomicrobia,2ITIZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae U SRP54-type protein, GTPase domain - - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N JFBFHGED_00490 349741.Amuc_0426 9.88e-242 666.0 COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia,2ITGQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Elongator protein 3, MiaB family, Radical SAM rlmN - 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM JFBFHGED_00491 349741.Amuc_0427 0.0 908.0 COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,2ITGD@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DnaB-like helicase C terminal domain - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C JFBFHGED_00493 349741.Amuc_0428 2.73e-151 430.0 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - DUF4347,Haemagg_act,PATR JFBFHGED_00494 349741.Amuc_0429 3.45e-145 409.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - ICMT,PEMT JFBFHGED_00495 349741.Amuc_0430 1.14e-270 744.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia,2ITHX@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Competence-damaged protein - - 3.5.1.42 ko:K03742 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth JFBFHGED_00496 349741.Amuc_0431 0.0 881.0 COG0469@1|root,COG0469@2|Bacteria,46SBJ@74201|Verrucomicrobia,2ITNV@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Pyruvate kinase, barrel domain - - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C JFBFHGED_00497 349741.Amuc_0432 5.74e-93 274.0 COG0454@1|root,COG0456@2|Bacteria,46WVW@74201|Verrucomicrobia 74201|Verrucomicrobia K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 JFBFHGED_00500 349741.Amuc_0436 5.39e-155 438.0 COG0560@1|root,COG0560@2|Bacteria,46XDN@74201|Verrucomicrobia,2IUJ7@203494|Verrucomicrobiae 203494|Verrucomicrobiae E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD JFBFHGED_00501 349741.Amuc_0437 3.59e-141 399.0 COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,2ITP0@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S4/S9 N-terminal domain - - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 JFBFHGED_00502 349741.Amuc_0438 1.17e-118 340.0 COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia,2IU6B@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 JFBFHGED_00503 349741.Amuc_0439 6.43e-79 235.0 COG0099@1|root,COG0099@2|Bacteria,46VYP@74201|Verrucomicrobia,2IUGG@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 JFBFHGED_00504 349741.Amuc_0440 2.11e-250 689.0 COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia,2ITS7@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Domain of unknown function (DUF1730) - - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16 JFBFHGED_00505 349741.Amuc_0441 8.29e-201 558.0 COG3660@1|root,COG3660@2|Bacteria,46VHN@74201|Verrucomicrobia,2IVP2@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Mitochondrial fission ELM1 - - - ko:K07276 - - - - ko00000 - - - Mito_fiss_Elm1 JFBFHGED_00506 349741.Amuc_0442 1.43e-251 692.0 COG0438@1|root,COG0438@2|Bacteria,46U78@74201|Verrucomicrobia,2IVJU@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JFBFHGED_00507 349741.Amuc_0443 4.1e-226 628.0 COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,2ITVU@203494|Verrucomicrobiae 203494|Verrucomicrobiae LU DNA recombination-mediator protein A - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A,HHH_5 JFBFHGED_00509 349741.Amuc_0444 1.46e-210 583.0 COG1686@1|root,COG1686@2|Bacteria,46SZY@74201|Verrucomicrobia,2IU54@203494|Verrucomicrobiae 203494|Verrucomicrobiae M D-alanyl-D-alanine carboxypeptidase - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11 JFBFHGED_00510 349741.Amuc_0445 4.83e-256 703.0 COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,2ITV8@203494|Verrucomicrobiae 203494|Verrucomicrobiae J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C JFBFHGED_00511 349741.Amuc_0446 7.4e-254 697.0 COG0404@1|root,COG0404@2|Bacteria,46UPA@74201|Verrucomicrobia,2ITVC@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminomethyltransferase folate-binding domain gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C JFBFHGED_00512 349741.Amuc_0447 6.67e-86 253.0 COG0509@1|root,COG0509@2|Bacteria,46VKU@74201|Verrucomicrobia,2IUJ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H JFBFHGED_00513 349741.Amuc_0448 0.0 1806.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,46S4N@74201|Verrucomicrobia,2ITRK@203494|Verrucomicrobiae 203494|Verrucomicrobiae E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvP - 1.4.4.2 ko:K00281 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko00002,ko01000 - - - GDC-P JFBFHGED_00514 411476.BACOVA_03033 1.37e-116 340.0 COG4188@1|root,COG4188@2|Bacteria,4NPB0@976|Bacteroidetes,2FP9I@200643|Bacteroidia,4AQ2X@815|Bacteroidaceae 976|Bacteroidetes S Alpha/beta hydrolase family - - - - - - - - - - - - Chlorophyllase2,Hydrolase_4 JFBFHGED_00515 349741.Amuc_0450 2.3e-99 293.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane - - - - - - - - - - - - DUF805 JFBFHGED_00516 349741.Amuc_0451 0.0 1339.0 COG3119@1|root,COG3119@2|Bacteria,46UIA@74201|Verrucomicrobia,2IVFY@203494|Verrucomicrobiae 2|Bacteria P PA14 domain - - - ko:K01138 - - - - ko00000,ko01000 - - - PA14,Sulfatase JFBFHGED_00518 349741.Amuc_0452 0.0 1068.0 COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia,2ITPY@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DbpA RNA binding domain - - 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,DbpA,Helicase_C JFBFHGED_00519 349741.Amuc_0453 1.17e-164 463.0 2CH0A@1|root,2ZANK@2|Bacteria,46V2X@74201|Verrucomicrobia,2IUG4@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00520 349741.Amuc_0454 0.0 948.0 COG2755@1|root,COG2755@2|Bacteria,46X92@74201|Verrucomicrobia,2IV2A@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Carbohydrate esterase, sialic acid-specific acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA JFBFHGED_00521 349741.Amuc_0455 3.1e-221 611.0 COG2755@1|root,COG2755@2|Bacteria,46XGP@74201|Verrucomicrobia,2IVVB@203494|Verrucomicrobiae 203494|Verrucomicrobiae E lipolytic protein G-D-S-L family - - - - - - - - - - - - - JFBFHGED_00522 349741.Amuc_0456 7.45e-96 280.0 COG2259@1|root,COG2259@2|Bacteria,46VKN@74201|Verrucomicrobia,2IUYQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX JFBFHGED_00523 349741.Amuc_0457 1.03e-239 659.0 COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia,2ITTU@203494|Verrucomicrobiae 203494|Verrucomicrobiae F AIR synthase related protein, N-terminal domain - - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C JFBFHGED_00524 349741.Amuc_0458 0.0 1287.0 COG0034@1|root,COG0034@2|Bacteria,46UKZ@74201|Verrucomicrobia,2ITSB@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - - JFBFHGED_00525 349741.Amuc_0459 3.6e-139 393.0 COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae 203494|Verrucomicrobiae K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 JFBFHGED_00527 349741.Amuc_0461 7.09e-178 499.0 COG0265@1|root,COG0265@2|Bacteria,46XRR@74201|Verrucomicrobia,2IWFN@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - - JFBFHGED_00528 349741.Amuc_0462 8.89e-80 237.0 COG2026@1|root,COG2026@2|Bacteria,46T5H@74201|Verrucomicrobia,2IUPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae DJ Addiction module toxin, RelE StbE family - - - - - - - - - - - - ParE_toxin JFBFHGED_00529 349741.Amuc_0463 8.3e-117 335.0 COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,2IUB8@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Flavoprotein - - 4.1.1.36 ko:K01598 ko00770,ko01100,map00770,map01100 M00120 R03269 RC00822 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein JFBFHGED_00531 349741.Amuc_0465 7.61e-245 673.0 COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,2IU1Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 JFBFHGED_00532 349741.Amuc_0466 0.0 1422.0 COG1729@1|root,COG1729@2|Bacteria,46T9I@74201|Verrucomicrobia,2IUIN@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - - - - - - - - - - TPR_16 JFBFHGED_00533 349741.Amuc_0467 7.4e-302 825.0 COG0494@1|root,COG2326@1|root,COG0494@2|Bacteria,COG2326@2|Bacteria,46UPR@74201|Verrucomicrobia,2IUNN@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 JFBFHGED_00534 349741.Amuc_0468 1.61e-169 474.0 COG1349@1|root,COG1349@2|Bacteria,46T4S@74201|Verrucomicrobia,2IUQ2@203494|Verrucomicrobiae 203494|Verrucomicrobiae K DeoR C terminal sensor domain - - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR JFBFHGED_00535 349741.Amuc_0469 2.42e-57 180.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - ko:K03826 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 JFBFHGED_00537 349741.Amuc_0470 8.83e-256 703.0 COG1104@1|root,COG1104@2|Bacteria,46TMY@74201|Verrucomicrobia,2ITTD@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class-V - - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 JFBFHGED_00538 349741.Amuc_0471 6.55e-155 435.0 COG0452@1|root,COG0452@2|Bacteria,46WUX@74201|Verrucomicrobia,2IU6G@203494|Verrucomicrobiae 203494|Verrucomicrobiae H DNA / pantothenate metabolism flavoprotein - - 6.3.2.5 ko:K21977 ko00770,map00770 M00120 R04231 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - DFP JFBFHGED_00539 349741.Amuc_0472 7.48e-260 713.0 COG1162@1|root,COG1162@2|Bacteria,46UNB@74201|Verrucomicrobia,2ITJY@203494|Verrucomicrobiae 203494|Verrucomicrobiae S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase JFBFHGED_00540 349741.Amuc_0473 1.94e-191 536.0 29SKQ@1|root,30DS1@2|Bacteria,46XQW@74201|Verrucomicrobia,2IWE1@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Aspartyl protease - - - - - - - - - - - - Asp_protease_2 JFBFHGED_00541 349741.Amuc_0474 1.29e-297 813.0 COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia,2ITS4@203494|Verrucomicrobiae 203494|Verrucomicrobiae M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) - - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N JFBFHGED_00542 349741.Amuc_0475 4.33e-118 339.0 COG0742@1|root,COG0742@2|Bacteria,46T62@74201|Verrucomicrobia,2IUEM@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Conserved hypothetical protein 95 - - - - - - - - - - - - Cons_hypoth95 JFBFHGED_00543 349741.Amuc_0476 1.31e-172 484.0 2C40J@1|root,33272@2|Bacteria,46X77@74201|Verrucomicrobia,2IUU6@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00545 349741.Amuc_0478 2.4e-205 570.0 COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia,2ITM1@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 JFBFHGED_00546 349741.Amuc_0480 0.0 1384.0 COG5434@1|root,COG5434@2|Bacteria,46W9Z@74201|Verrucomicrobia,2IV74@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Parallel beta-helix repeats - - - - - - - - - - - - Beta_helix,NPCBM JFBFHGED_00548 349741.Amuc_0482 2.11e-183 511.0 COG1073@1|root,COG1073@2|Bacteria,46WVD@74201|Verrucomicrobia,2IURZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S alpha beta - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6 JFBFHGED_00549 349741.Amuc_0483 1.36e-96 281.0 COG0802@1|root,COG0802@2|Bacteria,46T3C@74201|Verrucomicrobia,2IUJT@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE JFBFHGED_00550 349741.Amuc_0484 1.47e-61 189.0 COG0261@1|root,COG0261@2|Bacteria,46T6P@74201|Verrucomicrobia,2IUNR@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal prokaryotic L21 protein rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p JFBFHGED_00551 349741.Amuc_0485 2.51e-56 175.0 COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia,2IUMW@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal L27 protein rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 JFBFHGED_00552 349741.Amuc_0486 2.18e-96 281.0 COG0735@1|root,COG0735@2|Bacteria,46W8N@74201|Verrucomicrobia,2IUJS@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Ferric uptake regulator family - - - ko:K09825 - - - - ko00000,ko03000 - - - FUR JFBFHGED_00553 349741.Amuc_0487 2.2e-173 484.0 COG0396@1|root,COG0396@2|Bacteria,46SGE@74201|Verrucomicrobia,2ITY7@203494|Verrucomicrobiae 203494|Verrucomicrobiae O ATPases associated with a variety of cellular activities - - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran JFBFHGED_00554 349741.Amuc_0488 0.0 939.0 COG0719@1|root,COG0719@2|Bacteria,46SGN@74201|Verrucomicrobia,2IU30@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Uncharacterized protein family (UPF0051) - - - ko:K09014 - - - - ko00000 - - - UPF0051 JFBFHGED_00555 349741.Amuc_0489 3.83e-264 728.0 COG0719@1|root,COG0719@2|Bacteria,46S8S@74201|Verrucomicrobia,2ITRN@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Uncharacterized protein family (UPF0051) - - - ko:K09015 - - - - ko00000 - - - UPF0051 JFBFHGED_00556 296591.Bpro_5439 1.11e-100 305.0 COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2WH4T@28216|Betaproteobacteria,4AJV7@80864|Comamonadaceae 28216|Betaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_00557 349741.Amuc_0490 1.81e-271 773.0 COG4485@1|root,COG4485@2|Bacteria 2|Bacteria M Bacterial membrane protein, YfhO - - - - - - - - - - - - YfhO JFBFHGED_00558 349741.Amuc_0491 1.15e-45 159.0 COG3119@1|root,COG3119@2|Bacteria,46U02@74201|Verrucomicrobia,2ITYT@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Sulfatase - - - - - - - - - - - - Sulfatase JFBFHGED_00559 349741.Amuc_0492 1.01e-224 620.0 COG0502@1|root,COG0502@2|Bacteria,46S63@74201|Verrucomicrobia,2ITKQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Biotin and Thiamin Synthesis associated domain - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM JFBFHGED_00560 349741.Amuc_0493 0.0 879.0 COG0161@1|root,COG0161@2|Bacteria,46SBR@74201|Verrucomicrobia,2ITS3@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Aminotransferase class-III - - 2.6.1.62 ko:K00833 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03231 RC00006,RC00887 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 JFBFHGED_00563 349741.Amuc_0497 9.94e-71 213.0 COG2076@1|root,COG2076@2|Bacteria 2|Bacteria P Multidrug Resistance protein - - - ko:K03297,ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - EamA,Multi_Drug_Res,TPT JFBFHGED_00564 349741.Amuc_0498 8.6e-69 208.0 COG2076@1|root,COG2076@2|Bacteria 2|Bacteria P Multidrug Resistance protein - - - ko:K03297,ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - EamA,Multi_Drug_Res JFBFHGED_00565 349741.Amuc_0499 1.11e-212 588.0 COG0463@1|root,COG0463@2|Bacteria,46TW8@74201|Verrucomicrobia,2IW1Q@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_00566 349741.Amuc_0500 3.97e-95 279.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins flmH - 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_3 JFBFHGED_00567 349741.Amuc_0501 1.73e-268 735.0 COG0399@1|root,COG0399@2|Bacteria,46SEI@74201|Verrucomicrobia,2ITTP@203494|Verrucomicrobiae 203494|Verrucomicrobiae M DegT/DnrJ/EryC1/StrS aminotransferase family - - 2.6.1.59 ko:K02805 - - - - ko00000,ko01000,ko01007 - - - DegT_DnrJ_EryC1 JFBFHGED_00568 349741.Amuc_0502 4.24e-250 688.0 COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia,2IUUP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S COGs COG4299 conserved - - - - - - - - - - - - - JFBFHGED_00569 349741.Amuc_0503 1.19e-109 317.0 COG3091@1|root,COG3091@2|Bacteria 2|Bacteria K SprT-like family sprT - - - - - - - - - - - SprT-like JFBFHGED_00571 349741.Amuc_1143 0.0 1332.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00574 349741.Amuc_0504 9.98e-128 363.0 2FADU@1|root,342N6@2|Bacteria,46VMD@74201|Verrucomicrobia,2IUDF@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00575 349741.Amuc_0505 7.16e-90 264.0 COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,2IUNC@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N JFBFHGED_00576 349741.Amuc_0506 0.0 903.0 COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,2IU0R@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N JFBFHGED_00577 349741.Amuc_0507 1.14e-194 541.0 COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia,2ITXP@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt JFBFHGED_00578 349741.Amuc_0508 0.0 968.0 COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia,2ITR0@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N JFBFHGED_00579 349741.Amuc_0509 1.19e-72 220.0 COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae 203494|Verrucomicrobiae C ATP synthase delta (OSCP) subunit - - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP JFBFHGED_00580 349741.Amuc_0510 6.54e-73 224.0 COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia,2IUEN@203494|Verrucomicrobiae 203494|Verrucomicrobiae C ATP synthase B/B' CF(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B JFBFHGED_00581 452637.Oter_0880 2.34e-11 60.5 2BFTV@1|root,329NU@2|Bacteria,46Z0C@74201|Verrucomicrobia,3K8FB@414999|Opitutae 414999|Opitutae S PFAM H transporting two-sector ATPase C subunit - - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C JFBFHGED_00582 349741.Amuc_0512 6.04e-201 559.0 COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia,2IU94@203494|Verrucomicrobiae 203494|Verrucomicrobiae C ATP synthase A chain - - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A JFBFHGED_00583 349741.Amuc_0513 0.0 1192.0 2A0ZF@1|root,30P4Q@2|Bacteria,46X87@74201|Verrucomicrobia,2IUZ2@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00584 349741.Amuc_0514 0.0 1542.0 COG0768@1|root,COG0768@2|Bacteria,46TSQ@74201|Verrucomicrobia,2ITKB@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Penicillin-binding Protein dimerisation domain - - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase JFBFHGED_00585 349741.Amuc_0515 2.81e-141 399.0 COG1376@1|root,COG1376@2|Bacteria,46VEG@74201|Verrucomicrobia,2IUCG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD JFBFHGED_00586 349741.Amuc_0516 7.44e-227 629.0 COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia,2IUUP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S COGs COG4299 conserved - - - - - - - - - - - - - JFBFHGED_00588 349741.Amuc_0517 0.0 1229.0 COG3345@1|root,COG3345@2|Bacteria,46TWB@74201|Verrucomicrobia 74201|Verrucomicrobia G Raffinose synthase or seed imbibition protein Sip1 - - - - - - - - - - - - Raffinose_syn JFBFHGED_00590 349741.Amuc_0519 3.33e-208 575.0 COG0657@1|root,COG0657@2|Bacteria,46ZJ8@74201|Verrucomicrobia,2IUH2@203494|Verrucomicrobiae 203494|Verrucomicrobiae I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 JFBFHGED_00592 349741.Amuc_0521 1.22e-108 314.0 COG3247@1|root,COG3247@2|Bacteria 2|Bacteria U response to pH - - - - - - - - - - - - DUF308 JFBFHGED_00593 349741.Amuc_0522 5.13e-171 479.0 COG0476@1|root,COG0476@2|Bacteria,46SGF@74201|Verrucomicrobia,2IU1E@203494|Verrucomicrobiae 203494|Verrucomicrobiae H ThiF family - - - - - - - - - - - - Rhodanese,ThiF JFBFHGED_00594 349741.Amuc_0523 2.84e-216 598.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia,2ITHA@203494|Verrucomicrobiae 203494|Verrucomicrobiae M SIS domain - - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS JFBFHGED_00595 349741.Amuc_0524 4.79e-177 494.0 2E0WZ@1|root,32WDX@2|Bacteria,46WD0@74201|Verrucomicrobia,2IUTB@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00596 349741.Amuc_0525 5.74e-285 778.0 COG1657@1|root,COG1657@2|Bacteria,46U97@74201|Verrucomicrobia,2ITWF@203494|Verrucomicrobiae 203494|Verrucomicrobiae I PFAM Prenyltransferase squalene oxidase - - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - Prenyltrans JFBFHGED_00597 349741.Amuc_0526 9.07e-102 295.0 COG2259@1|root,COG2259@2|Bacteria,46T2M@74201|Verrucomicrobia,2IUPP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX JFBFHGED_00598 349741.Amuc_0527 3.27e-185 516.0 COG1045@1|root,COG1045@2|Bacteria,46UPZ@74201|Verrucomicrobia,2IWKR@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Serine acetyltransferase, N-terminal - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N JFBFHGED_00599 349741.Amuc_2045 1.32e-188 604.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Cadherin,Calx-beta,FG-GAP,Flg_new,Laminin_G_3,Lipase_GDSL_2,M60-like_N,PA14,Peptidase_M60 JFBFHGED_00600 349741.Amuc_0528 1.78e-284 780.0 COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia,2ITYN@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA - 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Aldedh JFBFHGED_00601 349741.Amuc_0529 1.28e-165 465.0 COG0263@1|root,COG0263@2|Bacteria,46SWM@74201|Verrucomicrobia,2IU7N@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB - 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA JFBFHGED_00602 332101.JIBU02000014_gene2422 2.21e-85 257.0 COG0693@1|root,COG0693@2|Bacteria,1V4K4@1239|Firmicutes,24C44@186801|Clostridia,36GPH@31979|Clostridiaceae 186801|Clostridia S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI JFBFHGED_00603 573370.DMR_34220 4.23e-308 844.0 COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria,2M91H@213115|Desulfovibrionales 28221|Deltaproteobacteria C Belongs to the catalase family katA - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel JFBFHGED_00605 349741.Amuc_0530 0.0 1252.0 COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,2ITKK@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N JFBFHGED_00606 349741.Amuc_0953 6.02e-43 172.0 COG3119@1|root,COG3119@2|Bacteria,46UIA@74201|Verrucomicrobia,2IVFY@203494|Verrucomicrobiae 203494|Verrucomicrobiae P PA14 domain - - - - - - - - - - - - PA14,Sulfatase JFBFHGED_00607 1235803.C825_00909 1.08e-117 376.0 COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,2FMGA@200643|Bacteroidia,22W18@171551|Porphyromonadaceae 976|Bacteroidetes P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase JFBFHGED_00609 349741.Amuc_0531 0.0 1131.0 COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia,2ITY2@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Transcription elongation factor, N-terminal - - - - - - - - - - - - GreA_GreB,GreA_GreB_N JFBFHGED_00613 349741.Amuc_0532 5.21e-164 459.0 COG0152@1|root,COG0152@2|Bacteria,46YXR@74201|Verrucomicrobia,2ITRI@203494|Verrucomicrobiae 203494|Verrucomicrobiae F SAICAR synthetase - - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt JFBFHGED_00614 349741.Amuc_0533 2.93e-97 284.0 2AWY0@1|root,31NVN@2|Bacteria,46XM4@74201|Verrucomicrobia,2IW6B@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00615 349741.Amuc_0534 0.0 1560.0 COG0046@1|root,COG0046@2|Bacteria,46S8Y@74201|Verrucomicrobia,2IUEK@203494|Verrucomicrobiae 203494|Verrucomicrobiae F involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,GATase_5 JFBFHGED_00616 349741.Amuc_0535 1.02e-174 486.0 COG0047@1|root,COG0047@2|Bacteria,46T5R@74201|Verrucomicrobia,2IV5H@203494|Verrucomicrobiae 203494|Verrucomicrobiae F CobB/CobQ-like glutamine amidotransferase domain - - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 JFBFHGED_00618 349741.Amuc_0537 1.05e-252 694.0 COG1363@1|root,COG1363@2|Bacteria,46SM3@74201|Verrucomicrobia,2IU2V@203494|Verrucomicrobiae 203494|Verrucomicrobiae G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 JFBFHGED_00620 349741.Amuc_0539 0.0 1721.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity lacZ_17 - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N JFBFHGED_00621 349741.Amuc_0540 5.06e-236 650.0 COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Actin - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl JFBFHGED_00622 349741.Amuc_0541 0.0 1003.0 COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia,2ITMW@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribonuclease E/G family - - - ko:K08301 - - - - ko00000,ko01000,ko03009,ko03019 - - - RNase_E_G JFBFHGED_00623 349741.Amuc_0542 4.33e-259 711.0 COG1522@1|root,COG1522@2|Bacteria,46SDK@74201|Verrucomicrobia,2IU3G@203494|Verrucomicrobiae 203494|Verrucomicrobiae K sequence-specific DNA binding - - - - - - - - - - - - - JFBFHGED_00624 1396418.BATQ01000007_gene1394 1.63e-20 104.0 COG4625@1|root,COG4625@2|Bacteria,46V8N@74201|Verrucomicrobia,2IVVJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae U TIGRFAM outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - JFBFHGED_00626 349741.Amuc_0544 0.0 2048.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46Z1Z@74201|Verrucomicrobia,2IUA3@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6 JFBFHGED_00628 349741.Amuc_0546 1.24e-98 287.0 COG0848@1|root,COG0848@2|Bacteria 2|Bacteria U biopolymer transport protein exbD2 - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD JFBFHGED_00629 349741.Amuc_0547 4.13e-98 287.0 COG0848@1|root,COG0848@2|Bacteria 2|Bacteria U biopolymer transport protein aglS - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD JFBFHGED_00630 349741.Amuc_0548 1.5e-165 465.0 COG0811@1|root,COG0811@2|Bacteria,46SY0@74201|Verrucomicrobia,2IUVE@203494|Verrucomicrobiae 203494|Verrucomicrobiae U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB JFBFHGED_00631 349741.Amuc_0549 1.01e-140 398.0 COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia,2IU17@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD JFBFHGED_00632 349741.Amuc_0550 5.9e-146 412.0 COG3584@1|root,COG3584@2|Bacteria,46VUB@74201|Verrucomicrobia,2IUCH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S 3D domain - - - - - - - - - - - - 3D JFBFHGED_00634 349741.Amuc_0551 4.18e-200 558.0 COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia,2IU8Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG JFBFHGED_00635 349741.Amuc_0552 2.72e-167 469.0 COG0134@1|root,COG0134@2|Bacteria,46V9B@74201|Verrucomicrobia,2ITZZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Indole-3-glycerol phosphate synthase - - 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS JFBFHGED_00636 335283.Neut_0049 2.97e-291 828.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,371XZ@32003|Nitrosomonadales 28216|Betaproteobacteria P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC actP - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS JFBFHGED_00637 349741.Amuc_0553 6.88e-73 219.0 COG0792@1|root,COG0792@2|Bacteria,46T9J@74201|Verrucomicrobia,2IUV7@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Uncharacterised protein family UPF0102 - - - ko:K07460 - - - - ko00000 - - - UPF0102 JFBFHGED_00638 349741.Amuc_0554 3.9e-134 382.0 COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,2IU98@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Ribonuclease HII - - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII JFBFHGED_00639 349741.Amuc_0555 4.07e-295 809.0 COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae 203494|Verrucomicrobiae S PFAM CBS domain containing protein - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 JFBFHGED_00640 349741.Amuc_0556 3.44e-58 179.0 2C1W8@1|root,2ZXK7@2|Bacteria,46WJJ@74201|Verrucomicrobia,2IUVQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Zinc ribbon domain - - - - - - - - - - - - Zn-ribbon_8 JFBFHGED_00641 349741.Amuc_0557 1.62e-53 168.0 COG0199@1|root,COG0199@2|Bacteria,46TBH@74201|Verrucomicrobia,2IUM9@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 JFBFHGED_00644 349741.Amuc_0559 9.69e-310 844.0 COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,2ITYG@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Arginosuccinate synthase argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth JFBFHGED_00645 595460.RRSWK_03587 2.52e-116 360.0 COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes 203682|Planctomycetes P COG3119 Arylsulfatase A - - 3.1.6.8 ko:K01134 ko00600,ko04142,map00600,map04142 - R04856 RC00231 ko00000,ko00001,ko01000 - - - Sulfatase JFBFHGED_00646 349741.Amuc_0561 4.31e-221 616.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,46TY0@74201|Verrucomicrobia,2ITWQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J 16S rRNA methyltransferase RsmB/F - - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,NusB JFBFHGED_00647 349741.Amuc_0562 5.79e-170 476.0 COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,2IU4R@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM JFBFHGED_00648 349741.Amuc_0563 1.43e-152 429.0 COG4968@1|root,COG4968@2|Bacteria 2|Bacteria NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl JFBFHGED_00649 349741.Amuc_0564 3.3e-137 389.0 2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,2IUHT@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00650 349741.Amuc_0565 0.0 951.0 COG3119@1|root,COG3119@2|Bacteria,46UNA@74201|Verrucomicrobia,2IV2G@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase JFBFHGED_00653 349741.Amuc_0568 4.42e-96 280.0 COG0824@1|root,COG0824@2|Bacteria,46T37@74201|Verrucomicrobia,2IUDB@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT JFBFHGED_00654 349741.Amuc_0569 1.97e-154 436.0 COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S competence protein - - - - - - - - - - - - Pribosyltran JFBFHGED_00655 349741.Amuc_0570 1.29e-64 197.0 29N4X@1|root,3092Q@2|Bacteria,46X7T@74201|Verrucomicrobia,2IUXE@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00656 349741.Amuc_0571 7.59e-178 497.0 COG1694@1|root,COG3956@2|Bacteria,46SNM@74201|Verrucomicrobia,2ITIM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S MazG nucleotide pyrophosphohydrolase domain - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - MazG JFBFHGED_00657 205922.Pfl01_3756 4.36e-07 64.7 COG2911@1|root,COG3210@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,1RY4P@1236|Gammaproteobacteria,1YM76@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria O Passenger-associated-transport-repeat - - - ko:K12685 - - - - ko00000,ko01000,ko02000,ko02044 1.B.12.5.1,1.B.12.5.3 - - Autotransporter,PAP2,PATR,Peptidase_S8 JFBFHGED_00659 349741.Amuc_0572 6.11e-74 221.0 2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00660 349741.Amuc_0573 5.44e-256 701.0 COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia,2IU03@203494|Verrucomicrobiae 203494|Verrucomicrobiae J 3'-5' exonuclease - - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC JFBFHGED_00662 349741.Amuc_0574 7.51e-118 342.0 COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia,2IUE8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S C4-type zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 JFBFHGED_00663 349741.Amuc_0575 7.3e-288 786.0 COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,2ITPT@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK JFBFHGED_00664 349741.Amuc_0576 0.0 2667.0 COG0612@1|root,COG0612@2|Bacteria,46UTT@74201|Verrucomicrobia,2ITM2@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C JFBFHGED_00665 349741.Amuc_0577 1.22e-108 314.0 29F7N@1|root,3025B@2|Bacteria,46WCY@74201|Verrucomicrobia,2IWD0@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00666 349741.Amuc_0578 1.79e-217 616.0 COG2268@1|root,COG2268@2|Bacteria,46XBU@74201|Verrucomicrobia,2IVCH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S prohibitin homologues - - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot JFBFHGED_00667 313628.LNTAR_22015 2.17e-44 153.0 2DM5T@1|root,31U0Y@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126 JFBFHGED_00668 267608.RSp1210 1.82e-05 43.9 COG5510@1|root,COG5510@2|Bacteria,1QB7E@1224|Proteobacteria,2WDS4@28216|Betaproteobacteria,1KAWC@119060|Burkholderiaceae 28216|Betaproteobacteria S Entericidin EcnA/B family - - - - - - - - - - - - Entericidin JFBFHGED_00669 349741.Amuc_0428 1.66e-10 68.2 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - DUF4347,Haemagg_act,PATR JFBFHGED_00671 349741.Amuc_0581 3.28e-200 555.0 COG0673@1|root,COG0673@2|Bacteria,46TDD@74201|Verrucomicrobia 74201|Verrucomicrobia S Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate - - 1.4.1.16 ko:K03340 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00526 R02755 RC00006 ko00000,ko00001,ko00002,ko01000 - - - DAPDH_C JFBFHGED_00672 349741.Amuc_0582 1.23e-150 426.0 COG3034@1|root,COG3034@2|Bacteria,46T6Y@74201|Verrucomicrobia,2IUG5@203494|Verrucomicrobiae 203494|Verrucomicrobiae S peptidoglycan biosynthetic process - - - - - - - - - - - - YkuD JFBFHGED_00673 349741.Amuc_0583 3.88e-120 344.0 COG4430@1|root,COG4430@2|Bacteria 2|Bacteria F Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA JFBFHGED_00674 349741.Amuc_0584 0.0 3626.0 COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter,ESPR,Haemagg_act,PATR JFBFHGED_00676 349741.Amuc_0585 0.0 1014.0 COG1171@1|root,COG1171@2|Bacteria,46S65@74201|Verrucomicrobia,2ITYU@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C JFBFHGED_00677 349741.Amuc_0586 7.42e-113 326.0 COG0424@1|root,COG0424@2|Bacteria,46VD8@74201|Verrucomicrobia,2IWJS@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Maf-like protein - - - ko:K06287 - - - - ko00000 - - - Maf JFBFHGED_00679 349741.Amuc_0587 3.58e-272 749.0 COG2262@1|root,COG2262@2|Bacteria,46SP4@74201|Verrucomicrobia,2IU26@203494|Verrucomicrobiae 203494|Verrucomicrobiae S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 JFBFHGED_00681 349741.Amuc_0589 0.0 906.0 COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia,2ITS0@203494|Verrucomicrobiae 203494|Verrucomicrobiae KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase JFBFHGED_00682 349741.Amuc_0589 1.77e-153 456.0 COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia,2ITS0@203494|Verrucomicrobiae 203494|Verrucomicrobiae KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase JFBFHGED_00683 349741.Amuc_0590 0.0 919.0 COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia,2IV14@203494|Verrucomicrobiae 203494|Verrucomicrobiae GK carbohydrate kinase activity - - - - - - - - - - - - - JFBFHGED_00684 349741.Amuc_0591 1.77e-183 514.0 COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,2IUVK@203494|Verrucomicrobiae 203494|Verrucomicrobiae S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi JFBFHGED_00685 349741.Amuc_0592 1.93e-190 531.0 COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia,2IU3R@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C JFBFHGED_00686 349741.Amuc_0593 0.0 1171.0 COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,46U4X@74201|Verrucomicrobia,2IU47@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_5,Acyltransferase JFBFHGED_00687 349741.Amuc_0594 8.26e-136 386.0 COG0283@1|root,COG0283@2|Bacteria,46VD5@74201|Verrucomicrobia,2IUAI@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Cytidylate kinase - - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin JFBFHGED_00688 349741.Amuc_0595 1.52e-142 402.0 COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,2IUG8@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase JFBFHGED_00689 349741.Amuc_0596 2.63e-242 667.0 COG1195@1|root,COG1195@2|Bacteria,46UKV@74201|Verrucomicrobia,2IUBX@203494|Verrucomicrobiae 203494|Verrucomicrobiae L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N JFBFHGED_00690 349741.Amuc_0597 7.53e-112 322.0 COG1853@1|root,COG1853@2|Bacteria 2|Bacteria S FMN binding actI - 1.5.1.36 ko:K00484 ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220 - R02698,R03299,R05705,R09748,R09750 RC00046,RC00126 ko00000,ko00001,ko01000 - - - Flavin_Reduct JFBFHGED_00691 349741.Amuc_0598 6.5e-151 426.0 COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc - 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm JFBFHGED_00692 349741.Amuc_0599 0.0 872.0 COG3746@1|root,COG3746@2|Bacteria,46T78@74201|Verrucomicrobia,2IUW9@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Phosphate-selective porin O and P - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P JFBFHGED_00694 349741.Amuc_0607 8.98e-143 407.0 COG3568@1|root,COG3568@2|Bacteria,46X7C@74201|Verrucomicrobia,2IUUK@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos JFBFHGED_00695 349741.Amuc_0608 2.27e-152 429.0 COG0313@1|root,COG0313@2|Bacteria,46SVC@74201|Verrucomicrobia,2IU7K@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Tetrapyrrole (Corrin/Porphyrin) Methylases rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase JFBFHGED_00696 349741.Amuc_0609 1.57e-108 313.0 2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia,2IUQI@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Lipopolysaccharide-assembly - - - - - - - - - - - - LptE JFBFHGED_00697 349741.Amuc_0610 1.24e-151 434.0 COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,2IUQE@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Outer membrane lipoprotein - - - ko:K05807 - - - - ko00000,ko02000 1.B.33.1 - - TPR_6,YfiO JFBFHGED_00698 349741.Amuc_0611 3.93e-114 327.0 COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,2IUFX@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Phosphoribosyl-AMP cyclohydrolase hisI - 3.5.4.19 ko:K01496 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04037 RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH JFBFHGED_00699 349741.Amuc_0612 1.25e-214 594.0 COG0470@1|root,COG0470@2|Bacteria,46T6T@74201|Verrucomicrobia,2IU8J@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C JFBFHGED_00701 349741.Amuc_0613 2.94e-111 320.0 COG3663@1|root,COG3663@2|Bacteria 2|Bacteria L G/U mismatch-specific uracil-DNA glycosylase activity - - 3.2.2.28 ko:K03649 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG JFBFHGED_00702 349741.Amuc_0614 3.72e-171 480.0 29JAD@1|root,3067W@2|Bacteria,46VPD@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - JFBFHGED_00703 349741.Amuc_0615 0.0 2031.0 COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae 2|Bacteria EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0661 CPSase_L_D2,CPSase_L_D3,MGS JFBFHGED_00704 349741.Amuc_0616 8.34e-137 393.0 COG0631@1|root,COG0631@2|Bacteria,46UCG@74201|Verrucomicrobia,2IWMM@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Serine/threonine phosphatases, family 2C, catalytic domain - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C_2 JFBFHGED_00706 349741.Amuc_0618 3.64e-150 425.0 COG0500@1|root,COG0500@2|Bacteria 2|Bacteria Q methyltransferase activity - - - - - - - - - - - - Methyltransf_11 JFBFHGED_00707 349741.Amuc_0620 0.0 1177.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46S9D@74201|Verrucomicrobia,2IUJE@203494|Verrucomicrobiae 203494|Verrucomicrobiae H NAD synthase - - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase JFBFHGED_00708 349741.Amuc_0621 5.83e-73 219.0 COG2076@1|root,COG2076@2|Bacteria,46W4K@74201|Verrucomicrobia,2IUY0@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Small Multidrug Resistance protein - - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res JFBFHGED_00709 349741.Amuc_0625 1.18e-282 774.0 COG4409@1|root,COG4409@2|Bacteria,46VEC@74201|Verrucomicrobia,2IUCZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae G BNR/Asp-box repeat - - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2 JFBFHGED_00710 349741.Amuc_0124 1.23e-194 553.0 COG5301@1|root,COG5301@2|Bacteria,46UXN@74201|Verrucomicrobia,2IW6U@203494|Verrucomicrobiae 203494|Verrucomicrobiae G cellulose 1,4-beta-cellobiosidase activity - - - - - - - - - - - - - JFBFHGED_00711 1121028.ARQE01000001_gene3610 2.17e-97 304.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,2TRWI@28211|Alphaproteobacteria,2PK7I@255475|Aurantimonadaceae 28211|Alphaproteobacteria S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 JFBFHGED_00713 349741.Amuc_0627 0.0 954.0 COG4166@1|root,COG4166@2|Bacteria 2|Bacteria E transmembrane transport - - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - M60-like_N,Peptidase_M60,SBP_bac_5 JFBFHGED_00714 1229205.BUPH_06604 2.29e-28 118.0 COG1100@1|root,COG1100@2|Bacteria,1QUET@1224|Proteobacteria 1224|Proteobacteria T TIR domain - - - - - - - - - - - - TIR_2 JFBFHGED_00715 296591.Bpro_3315 1.8e-117 353.0 28IAZ@1|root,2Z8DG@2|Bacteria,1PWB4@1224|Proteobacteria,2WBVX@28216|Betaproteobacteria,4AIET@80864|Comamonadaceae 28216|Betaproteobacteria S DNA-sulfur modification-associated - - - - - - - - - - - - DndB JFBFHGED_00718 349741.Amuc_2019 1.32e-164 482.0 COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae 2|Bacteria G Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_00719 349741.Amuc_0629 1.06e-235 649.0 COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia,2ITRW@203494|Verrucomicrobiae 203494|Verrucomicrobiae L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N JFBFHGED_00720 349741.Amuc_0630 3.64e-227 627.0 COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C JFBFHGED_00721 349741.Amuc_0631 2.08e-263 722.0 COG0369@1|root,COG0369@2|Bacteria,46SEE@74201|Verrucomicrobia,2ITWD@203494|Verrucomicrobiae 203494|Verrucomicrobiae P FAD binding domain - - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1 JFBFHGED_00722 349741.Amuc_0633 4.25e-103 314.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_00725 349741.Amuc_0632 1.52e-214 597.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 MA20_42350 - 2.7.8.12 ko:K09809 - - - - ko00000,ko01000 - - - Glycos_transf_2 JFBFHGED_00727 349741.Amuc_0633 7.24e-79 244.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_00728 349741.Amuc_0634 6.11e-207 574.0 COG1442@1|root,COG1442@2|Bacteria,46WTH@74201|Verrucomicrobia 74201|Verrucomicrobia H PFAM glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 JFBFHGED_00731 349741.Amuc_0636 0.0 912.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - Polysacc_synt JFBFHGED_00732 349741.Amuc_0637 9e-182 517.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JFBFHGED_00733 349741.Amuc_0638 3.41e-120 360.0 COG0438@1|root,COG0438@2|Bacteria,46TH7@74201|Verrucomicrobia,2IVWS@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 JFBFHGED_00734 349741.Amuc_0639 5.47e-106 310.0 COG0110@1|root,COG0110@2|Bacteria,46T6H@74201|Verrucomicrobia,2IW2C@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - - JFBFHGED_00735 349741.Amuc_0642 4.23e-174 490.0 COG0324@1|root,COG0324@2|Bacteria,46T1C@74201|Verrucomicrobia,2IU70@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA - 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT JFBFHGED_00738 349741.Amuc_0644 8.94e-252 692.0 COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia,2ITRY@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans JFBFHGED_00739 349741.Amuc_0645 5.8e-291 798.0 COG0486@1|root,COG0486@2|Bacteria,46SIQ@74201|Verrucomicrobia,2ITV2@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N JFBFHGED_00740 1122990.BAJH01000008_gene1270 3.57e-92 273.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH_4 JFBFHGED_00741 349741.Amuc_0647 1.63e-140 399.0 COG2860@1|root,COG2860@2|Bacteria,46T5E@74201|Verrucomicrobia,2IUJG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S UPF0126 domain - - - - - - - - - - - - UPF0126 JFBFHGED_00742 349741.Amuc_0648 2.89e-177 494.0 COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia,2IU55@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B_2 JFBFHGED_00743 349741.Amuc_0649 3.59e-102 296.0 COG2001@1|root,COG2001@2|Bacteria,46X89@74201|Verrucomicrobia,2IUZJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Belongs to the MraZ family - - - ko:K03925 - - - - ko00000 - - - - JFBFHGED_00744 349741.Amuc_0650 0.0 915.0 COG0275@1|root,COG0275@2|Bacteria,46SPT@74201|Verrucomicrobia,2IU2A@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH - 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 JFBFHGED_00746 349741.Amuc_0652 0.0 1332.0 COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,2ITJE@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Penicillin-binding Protein dimerisation domain - - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase JFBFHGED_00747 349741.Amuc_0653 0.0 976.0 COG0769@1|root,COG0769@2|Bacteria,46SGG@74201|Verrucomicrobia,2ITRP@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M JFBFHGED_00748 349741.Amuc_0654 7.31e-305 834.0 COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia,2ITUQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Mur ligase middle domain - - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M JFBFHGED_00749 349741.Amuc_0655 1.54e-249 686.0 COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,2ITSQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 JFBFHGED_00750 349741.Amuc_0656 1.85e-285 783.0 COG0771@1|root,COG0771@2|Bacteria,46UUH@74201|Verrucomicrobia,2ITN5@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M JFBFHGED_00751 349741.Amuc_0657 8.87e-148 421.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain mltD - - ko:K08307,ko:K12204,ko:K19224 - - - - ko00000,ko01000,ko01002,ko01011,ko02044 3.A.7.10.1,3.A.7.9.1 CBM50 - LysM,NLPC_P60,SLT,T4SS_TraI JFBFHGED_00752 349741.Amuc_0658 3.51e-273 747.0 COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia,2ITN2@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Cell cycle protein - - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE JFBFHGED_00753 349741.Amuc_0659 2.89e-253 696.0 COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia,2ITPN@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 JFBFHGED_00754 349741.Amuc_0660 0.0 1440.0 COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,2ITNT@203494|Verrucomicrobiae 203494|Verrucomicrobiae M UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain murB - - - - - - - - - - - FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M JFBFHGED_00755 349741.Amuc_0661 4.68e-209 579.0 COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,2IU29@203494|Verrucomicrobiae 203494|Verrucomicrobiae M D-ala D-ala ligase N-terminus ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N JFBFHGED_00756 349741.Amuc_0662 2.31e-203 564.0 COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,2IUSI@203494|Verrucomicrobiae 203494|Verrucomicrobiae M POTRA domain, FtsQ-type - - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - POTRA_1 JFBFHGED_00757 349741.Amuc_0663 2.38e-231 639.0 COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,2ITWB@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA JFBFHGED_00758 349741.Amuc_0664 1.33e-229 634.0 COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,2IU3W@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Ami_3 - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 JFBFHGED_00759 349741.Amuc_0665 7.98e-117 338.0 COG0321@1|root,COG0321@2|Bacteria,46T11@74201|Verrucomicrobia,2IUBF@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Biotin/lipoate A/B protein ligase family - - 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB JFBFHGED_00760 349741.Amuc_0666 0.0 921.0 COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia,2ITJH@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aconitase family (aconitate hydratase) - - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase JFBFHGED_00761 349741.Amuc_0667 1.35e-140 397.0 COG0066@1|root,COG0066@2|Bacteria,46TAY@74201|Verrucomicrobia,2IU7P@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aconitase C-terminal domain - - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C JFBFHGED_00762 349741.Amuc_0668 4.95e-249 686.0 2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia,2IUNI@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00763 349741.Amuc_0669 0.0 999.0 COG0265@1|root,COG0265@2|Bacteria,46UAN@74201|Verrucomicrobia,2ITY6@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Trypsin - - - - - - - - - - - - PDZ_2,Trypsin_2 JFBFHGED_00764 349741.Amuc_0670 0.0 909.0 COG0265@1|root,COG0265@2|Bacteria,46SZ1@74201|Verrucomicrobia,2ITZC@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 JFBFHGED_00765 349741.Amuc_0671 2.42e-263 723.0 COG0337@1|root,COG0337@2|Bacteria,46UQ7@74201|Verrucomicrobia,2ITKA@203494|Verrucomicrobiae 203494|Verrucomicrobiae E 3-dehydroquinate synthase - - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase JFBFHGED_00766 658659.HMPREF0983_04111 1.83e-136 402.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,3VQ96@526524|Erysipelotrichia 1239|Firmicutes E Peptidase dimerisation domain amaA - - - - - - - - - - - M20_dimer,Peptidase_M20 JFBFHGED_00767 349741.Amuc_1143 0.0 1386.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00769 349741.Amuc_0672 4.49e-164 461.0 COG4608@1|root,COG4608@2|Bacteria,46SHJ@74201|Verrucomicrobia,2ITZ2@203494|Verrucomicrobiae 203494|Verrucomicrobiae E ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran JFBFHGED_00771 349741.Amuc_0673 9.41e-183 511.0 COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia,2IU52@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS JFBFHGED_00772 349741.Amuc_0674 3.38e-160 450.0 COG0052@1|root,COG0052@2|Bacteria,46SNG@74201|Verrucomicrobia,2ITPQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S2 rpsB - - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 JFBFHGED_00773 545243.BAEV01000009_gene1243 2.43e-196 559.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,36DT9@31979|Clostridiaceae 186801|Clostridia V Mate efflux family protein - - - - - - - - - - - - MatE JFBFHGED_00774 349741.Amuc_0675 3.62e-92 278.0 COG2138@1|root,COG2138@2|Bacteria 2|Bacteria S sirohydrochlorin cobaltochelatase activity cbiX - 4.99.1.3 ko:K03795 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05807 RC01012 ko00000,ko00001,ko01000 - - - CbiX JFBFHGED_00775 349741.Amuc_0676 3.05e-194 538.0 COG2877@1|root,COG2877@2|Bacteria,46SMZ@74201|Verrucomicrobia,2IU2C@203494|Verrucomicrobiae 203494|Verrucomicrobiae M DAHP synthetase I family - - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 JFBFHGED_00778 349741.Amuc_0679 8.84e-162 454.0 COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,2IU2S@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ATPases associated with a variety of cellular activities - - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran JFBFHGED_00779 349741.Amuc_0680 7.34e-218 600.0 COG0560@1|root,COG0560@2|Bacteria,46UCT@74201|Verrucomicrobia,2ITII@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Phosphoserine phosphatase - - - - - - - - - - - - HAD JFBFHGED_00780 349741.Amuc_0681 0.0 895.0 COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia,2ITID@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Mur ligase family, catalytic domain - - 6.3.2.45 ko:K02558 - - - - ko00000,ko01000 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M JFBFHGED_00781 349741.Amuc_0682 1.88e-291 798.0 COG2885@1|root,COG2885@2|Bacteria,46ZBB@74201|Verrucomicrobia,2IU9R@203494|Verrucomicrobiae 203494|Verrucomicrobiae M OmpA family - - - - - - - - - - - - OmpA JFBFHGED_00782 349741.Amuc_0683 0.0 1290.0 COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia,2ITJF@203494|Verrucomicrobiae 203494|Verrucomicrobiae L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C JFBFHGED_00784 349741.Amuc_0687 0.0 1576.0 COG4625@1|root,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter JFBFHGED_00786 349741.Amuc_0689 0.0 879.0 COG0017@1|root,COG0017@2|Bacteria,46TN6@74201|Verrucomicrobia,2ITHF@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class II (D, K and N) asnS - 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon JFBFHGED_00787 349741.Amuc_0690 1.09e-270 744.0 COG3271@1|root,COG3271@2|Bacteria,46WD7@74201|Verrucomicrobia,2IUDZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00788 349741.Amuc_0691 7.28e-71 213.0 COG3118@1|root,COG3118@2|Bacteria,46VWK@74201|Verrucomicrobia,2IUMX@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Thioredoxin-like domain - - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin JFBFHGED_00790 349741.Amuc_0693 1e-147 417.0 COG4262@1|root,COG4262@2|Bacteria,46Z6I@74201|Verrucomicrobia,2IVWZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - - JFBFHGED_00791 349741.Amuc_0694 3.2e-251 693.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02022 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD,HlyD_3 JFBFHGED_00792 349741.Amuc_0695 7.3e-287 784.0 COG1657@1|root,COG1657@2|Bacteria,46XAC@74201|Verrucomicrobia,2IV6H@203494|Verrucomicrobiae 2|Bacteria I PFAM Prenyltransferase squalene oxidase - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 4.2.1.129,5.4.99.17,5.5.1.16 ko:K06045,ko:K17811 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - Prenyltrans,SQHop_cyclase_C JFBFHGED_00793 349741.Amuc_0696 3.32e-283 776.0 COG1657@1|root,COG1657@2|Bacteria,46XAC@74201|Verrucomicrobia,2IV6H@203494|Verrucomicrobiae 203494|Verrucomicrobiae I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - - JFBFHGED_00794 349741.Amuc_0698 3.16e-257 706.0 COG3507@1|root,COG3507@2|Bacteria,46Z6J@74201|Verrucomicrobia,2IV24@203494|Verrucomicrobiae 2|Bacteria M Belongs to the glycosyl hydrolase 43 family - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_43,RicinB_lectin_2 JFBFHGED_00798 349741.Amuc_0701 4.63e-188 526.0 COG0583@1|root,COG0583@2|Bacteria,46SDJ@74201|Verrucomicrobia,2IU8Q@203494|Verrucomicrobiae 203494|Verrucomicrobiae K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate JFBFHGED_00799 349741.Amuc_0702 1.91e-218 605.0 COG2855@1|root,COG2855@2|Bacteria,46WQA@74201|Verrucomicrobia 74201|Verrucomicrobia S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 JFBFHGED_00800 349741.Amuc_0703 6.7e-236 650.0 COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,2IU5S@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class-V - - - - - - - - - - - - Aminotran_5 JFBFHGED_00802 349741.Amuc_0704 2.6e-296 809.0 COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,2IV8W@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF1015) - - - - - - - - - - - - DUF1015 JFBFHGED_00803 349741.Amuc_0705 0.0 983.0 COG0111@1|root,COG0111@2|Bacteria,46Z6K@74201|Verrucomicrobia,2ITN1@203494|Verrucomicrobiae 203494|Verrucomicrobiae EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT JFBFHGED_00804 349741.Amuc_0706 4.14e-145 421.0 COG4372@1|root,COG4372@2|Bacteria 2|Bacteria Q Transposase - - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - EzrA JFBFHGED_00805 349741.Amuc_0707 1.08e-147 417.0 COG0602@1|root,COG0602@2|Bacteria,46SW0@74201|Verrucomicrobia,2IUF0@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds - - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM JFBFHGED_00806 349741.Amuc_0708 0.0 970.0 COG1158@1|root,COG1158@2|Bacteria,46UQY@74201|Verrucomicrobia,2ITRJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_RNA_bind JFBFHGED_00807 349741.Amuc_0709 1.13e-170 477.0 COG0217@1|root,COG0217@2|Bacteria,46SP3@74201|Verrucomicrobia,2IU5Q@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Transcriptional regulator - - - - - - - - - - - - Transcrip_reg JFBFHGED_00809 349741.Amuc_0710 0.0 872.0 COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Dimerisation domain of Zinc Transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer JFBFHGED_00810 720554.Clocl_0234 8.5e-117 340.0 COG0500@1|root,COG2226@2|Bacteria,1TR6N@1239|Firmicutes,2494W@186801|Clostridia,3WNIC@541000|Ruminococcaceae 186801|Clostridia H Methylase involved in ubiquinone menaquinone biosynthesis - - - - - - - - - - - - Methyltransf_11 JFBFHGED_00811 349741.Amuc_0711 0.0 1010.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,46UN8@74201|Verrucomicrobia,2IV26@203494|Verrucomicrobiae 203494|Verrucomicrobiae P TrkA-N domain - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N JFBFHGED_00812 349741.Amuc_1537 6.9e-120 422.0 COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter,ESPR,Haemagg_act,PATR JFBFHGED_00814 349741.Amuc_0713 1.15e-234 645.0 COG0809@1|root,COG0809@2|Bacteria,46SDA@74201|Verrucomicrobia,2IU22@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA - 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth JFBFHGED_00815 349741.Amuc_0714 9.37e-197 551.0 COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,2ITH8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S SigmaW regulon antibacterial - - - - - - - - - - - - YdfA_immunity JFBFHGED_00817 349741.Amuc_0716 3.43e-165 464.0 COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia,2ITYP@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Thiazole biosynthesis protein ThiG - - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG JFBFHGED_00818 349741.Amuc_0717 1.9e-262 724.0 COG0531@1|root,COG0531@2|Bacteria,46W3Q@74201|Verrucomicrobia,2IWAN@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Amino acid permease - - - - - - - - - - - - AA_permease_2 JFBFHGED_00819 349741.Amuc_0718 3.06e-135 385.0 COG0546@1|root,COG0546@2|Bacteria 2|Bacteria S glycolate biosynthetic process gph - 3.1.3.18,3.6.1.1 ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 JFBFHGED_00820 349741.Amuc_0719 4.37e-246 678.0 COG0628@1|root,COG0628@2|Bacteria,46U8S@74201|Verrucomicrobia,2IU6H@203494|Verrucomicrobiae 203494|Verrucomicrobiae S AI-2E family transporter - - - ko:K11744 - - - - ko00000 - - - AI-2E_transport JFBFHGED_00821 349741.Amuc_0720 1.03e-299 818.0 COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC JFBFHGED_00822 349741.Amuc_1260 5.49e-288 794.0 COG3408@1|root,COG3408@2|Bacteria,46UWR@74201|Verrucomicrobia,2IVIK@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Trehalase - - - - - - - - - - - - - JFBFHGED_00823 349741.Amuc_0868 5.77e-187 543.0 COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_00824 349741.Amuc_0721 2.19e-234 645.0 COG0191@1|root,COG0191@2|Bacteria,46UMQ@74201|Verrucomicrobia,2ITR6@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase JFBFHGED_00825 1125973.JNLC01000001_gene71 3.98e-40 154.0 2AK27@1|root,31ARV@2|Bacteria,1REZR@1224|Proteobacteria,2UE1H@28211|Alphaproteobacteria,3K4PT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - JFBFHGED_00827 1448389.BAVQ01000072_gene2657 4.4e-12 75.5 2AK27@1|root,31ARV@2|Bacteria,2IFAT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - JFBFHGED_00828 365044.Pnap_3188 1.18e-25 112.0 COG5039@1|root,COG5039@2|Bacteria,1RJWU@1224|Proteobacteria 1224|Proteobacteria GM Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans JFBFHGED_00829 349741.Amuc_0722 0.0 1205.0 COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia,2ITJK@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Elongation factor G C-terminus - - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 JFBFHGED_00830 349741.Amuc_0723 1.57e-200 556.0 COG0115@1|root,COG0115@2|Bacteria,46S9W@74201|Verrucomicrobia,2ITHT@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 JFBFHGED_00831 349741.Amuc_0724 5.49e-215 593.0 COG2273@1|root,COG2273@2|Bacteria,46UCB@74201|Verrucomicrobia,2IUFQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolases family 16 - - - - - - - - - - - - Glyco_hydro_16 JFBFHGED_00832 349741.Amuc_0725 1.2e-106 310.0 COG0350@1|root,COG0350@2|Bacteria,46T3E@74201|Verrucomicrobia,2IUK7@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N JFBFHGED_00833 349741.Amuc_0726 8.16e-113 327.0 COG1716@1|root,COG1716@2|Bacteria 2|Bacteria T histone H2A K63-linked ubiquitination - - - - - - - - - - - - DUF4388,FHA,Yop-YscD_cpl JFBFHGED_00834 1401078.HMPREF2140_01320 2.23e-25 100.0 COG3152@1|root,COG3152@2|Bacteria,4NS95@976|Bacteroidetes,2FTZE@200643|Bacteroidia 976|Bacteroidetes S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 JFBFHGED_00835 349741.Amuc_0728 1.18e-252 693.0 COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia,2ITSD@203494|Verrucomicrobiae 203494|Verrucomicrobiae S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 JFBFHGED_00836 349741.Amuc_0729 1.49e-272 746.0 COG2334@1|root,COG2334@2|Bacteria,46Z6M@74201|Verrucomicrobia,2IU0S@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Phosphotransferase enzyme family - - - - - - - - - - - - APH JFBFHGED_00837 349741.Amuc_0730 1.29e-237 654.0 COG1181@1|root,COG1181@2|Bacteria 2|Bacteria F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N JFBFHGED_00838 349741.Amuc_0731 4.15e-236 650.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 JFBFHGED_00842 349741.Amuc_0735 0.0 2255.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00843 349741.Amuc_0736 2.44e-106 307.0 COG0394@1|root,COG0394@2|Bacteria,46VNK@74201|Verrucomicrobia,2IUIM@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Low molecular weight phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc JFBFHGED_00844 349741.Amuc_0737 0.0 914.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46W51@74201|Verrucomicrobia,2ITJ9@203494|Verrucomicrobiae 203494|Verrucomicrobiae F IMP dehydrogenase / GMP reductase domain - - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH JFBFHGED_00845 349741.Amuc_0738 0.0 999.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,2ITUH@203494|Verrucomicrobiae 203494|Verrucomicrobiae F GMP synthase C terminal domain - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase JFBFHGED_00846 642492.Clole_0384 3.86e-145 414.0 COG2265@1|root,COG2265@2|Bacteria,1UMH7@1239|Firmicutes,25GI5@186801|Clostridia 186801|Clostridia J Methyltransferase domain - - - - - - - - - - - - Methyltransf_31 JFBFHGED_00847 349741.Amuc_0739 6.65e-131 372.0 COG0110@1|root,COG0110@2|Bacteria,46TEB@74201|Verrucomicrobia,2IUHQ@203494|Verrucomicrobiae 74201|Verrucomicrobia S Maltose acetyltransferase - - - - - - - - - - - - Hexapep,Mac JFBFHGED_00848 349741.Amuc_0740 1.71e-126 362.0 COG0546@1|root,COG0546@2|Bacteria 2|Bacteria S glycolate biosynthetic process ppaX_1 - 3.1.3.18,3.6.1.1 ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 JFBFHGED_00849 349741.Amuc_0742 2.8e-230 634.0 COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia,2IUBD@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans JFBFHGED_00850 349741.Amuc_0743 2.7e-106 308.0 2EMM1@1|root,33F9E@2|Bacteria,46TBT@74201|Verrucomicrobia,2IUX2@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00851 349741.Amuc_0744 4.26e-250 687.0 COG0722@1|root,COG0722@2|Bacteria,46TIT@74201|Verrucomicrobia,2IU3E@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) - - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 JFBFHGED_00852 349741.Amuc_0745 2.8e-143 405.0 COG4969@1|root,COG4969@2|Bacteria,46ZJH@74201|Verrucomicrobia,2IUWI@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl JFBFHGED_00853 349741.Amuc_0746 1.43e-80 242.0 COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,2IUIB@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Preprotein translocase SecG subunit - - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG JFBFHGED_00854 349741.Amuc_0747 9e-65 197.0 COG0853@1|root,COG0853@2|Bacteria,46W3T@74201|Verrucomicrobia,2IUIC@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox JFBFHGED_00855 349741.Amuc_0748 7.27e-197 548.0 COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Riboflavin kinase - - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase JFBFHGED_00856 349741.Amuc_0749 1.15e-158 446.0 COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,2ITQ8@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB - 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C_2,TruB_N JFBFHGED_00857 349741.Amuc_0750 3.55e-233 642.0 COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia,2ITUW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DHHA1 domain - - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 JFBFHGED_00859 349741.Amuc_0752 8.47e-182 508.0 COG1408@1|root,COG1408@2|Bacteria 2|Bacteria S Calcineurin-like phosphoesterase lpxG - - ko:K07098 - - - - ko00000 - - - Metallophos JFBFHGED_00861 349741.Amuc_0753 1.81e-228 630.0 COG1442@1|root,COG1442@2|Bacteria,46WTH@74201|Verrucomicrobia 74201|Verrucomicrobia H PFAM glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 JFBFHGED_00862 349741.Amuc_0754 1.07e-220 611.0 COG1216@1|root,COG1216@2|Bacteria,46TK6@74201|Verrucomicrobia,2IUYU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_00863 349741.Amuc_0755 2.81e-212 588.0 COG0859@1|root,COG0859@2|Bacteria 2|Bacteria M ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_tran_WbsX,Glyco_transf_9 JFBFHGED_00864 349741.Amuc_0756 1.19e-231 638.0 COG0451@1|root,COG0451@2|Bacteria,46TV3@74201|Verrucomicrobia,2IVB1@203494|Verrucomicrobiae 203494|Verrucomicrobiae M 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.20 ko:K03274 ko00540,ko01100,map00540,map01100 M00064 R05176 RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase JFBFHGED_00865 349741.Amuc_0757 1.68e-257 708.0 COG0463@1|root,COG0463@2|Bacteria,46Z6N@74201|Verrucomicrobia,2IW83@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_00866 349741.Amuc_0758 1.18e-185 516.0 2A4B8@1|root,30SWV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_00867 349741.Amuc_0759 3.06e-255 704.0 COG0438@1|root,COG0438@2|Bacteria,46W11@74201|Verrucomicrobia,2IW0T@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4 JFBFHGED_00868 349741.Amuc_0760 1.77e-235 648.0 28IN0@1|root,2Z8NG@2|Bacteria,46W43@74201|Verrucomicrobia 74201|Verrucomicrobia S Glycosyltransferase family 10 (fucosyltransferase) C-term - - - - - - - - - - - - Glyco_transf_10 JFBFHGED_00869 349741.Amuc_0761 0.0 1273.0 COG1835@1|root,COG1835@2|Bacteria,46X8A@74201|Verrucomicrobia,2IUZP@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_00870 349741.Amuc_0762 1.58e-239 659.0 28IIB@1|root,30IUU@2|Bacteria,46V5V@74201|Verrucomicrobia,2IWAJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Glycosyltransferase family 10 (fucosyltransferase) C-term - - - - - - - - - - - - Glyco_transf_10 JFBFHGED_00873 349741.Amuc_0766 0.0 1085.0 COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,46UA9@74201|Verrucomicrobia,2ITKW@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Citrate transporter - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C JFBFHGED_00875 349741.Amuc_0767 7.61e-102 296.0 COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,2IUQJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Bifunctional nuclease - - - ko:K08999 - - - - ko00000 - - - DNase-RNase JFBFHGED_00876 349741.Amuc_0768 1.87e-108 314.0 COG0663@1|root,COG0663@2|Bacteria,46V7F@74201|Verrucomicrobia,2IU9X@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep JFBFHGED_00877 349741.Amuc_0769 0.0 1216.0 COG1305@1|root,COG1305@2|Bacteria,46VXQ@74201|Verrucomicrobia,2IUIY@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Transglutaminase-like - - - - - - - - - - - - - JFBFHGED_00878 349741.Amuc_0770 1.85e-134 383.0 COG0778@1|root,COG0778@2|Bacteria,46WEH@74201|Verrucomicrobia 74201|Verrucomicrobia C Nitroreductase family - - - - - - - - - - - - Nitroreductase JFBFHGED_00879 1214065.BAGV01000091_gene344 1.57e-47 160.0 COG2365@1|root,COG2365@2|Bacteria,1RGE7@1224|Proteobacteria,1S66H@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Tyrosine phosphatase family - - - - - - - - - - - - DSPc,Y_phosphatase2 JFBFHGED_00880 349741.Amuc_0771 0.0 1290.0 COG1874@1|root,COG1874@2|Bacteria,46UVE@74201|Verrucomicrobia,2IU38@203494|Verrucomicrobiae 2|Bacteria G Glycosyl hydrolases family 35 - - 3.2.1.23 ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - BetaGal_dom4_5,Glyco_hydro_35 JFBFHGED_00881 349741.Amuc_0772 4.05e-171 492.0 COG0588@1|root,COG1052@1|root,COG0588@2|Bacteria,COG1052@2|Bacteria,46SGM@74201|Verrucomicrobia,2ITY0@203494|Verrucomicrobiae 203494|Verrucomicrobiae CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C JFBFHGED_00882 349741.Amuc_0772 1.93e-234 656.0 COG0588@1|root,COG1052@1|root,COG0588@2|Bacteria,COG1052@2|Bacteria,46SGM@74201|Verrucomicrobia,2ITY0@203494|Verrucomicrobiae 203494|Verrucomicrobiae CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C JFBFHGED_00885 349741.Amuc_0773 1.55e-271 743.0 COG1835@1|root,COG1835@2|Bacteria 2|Bacteria I transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_00886 349741.Amuc_0774 2.68e-297 816.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily hsrA - - - - - - - - - - - MFS_1,Sugar_tr JFBFHGED_00887 349741.Amuc_0775 6.61e-100 290.0 COG1607@1|root,COG1607@2|Bacteria 2|Bacteria I acyl-coa hydrolase yciA - - ko:K10806 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT JFBFHGED_00890 1123075.AUDP01000022_gene3614 1.26e-69 217.0 COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24G7P@186801|Clostridia,3WIDA@541000|Ruminococcaceae 186801|Clostridia P Psort location CytoplasmicMembrane, score - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp JFBFHGED_00891 1158601.I585_01519 5.52e-72 222.0 COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HH2P@91061|Bacilli,4B1PN@81852|Enterococcaceae 91061|Bacilli P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp JFBFHGED_00892 349741.Amuc_0777 2.72e-190 533.0 COG1028@1|root,COG1028@2|Bacteria,46SN5@74201|Verrucomicrobia,2IUJB@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ KR domain - - - - - - - - - - - - adh_short_C2 JFBFHGED_00893 693746.OBV_38680 1.91e-286 808.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,2N8C3@216572|Oscillospiraceae 186801|Clostridia P Ferrous iron transport protein B C terminus feoB2 - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate JFBFHGED_00894 537013.CLOSTMETH_00606 4.68e-20 82.8 COG1918@1|root,COG1918@2|Bacteria,1VFH1@1239|Firmicutes,24R3D@186801|Clostridia,3WKWS@541000|Ruminococcaceae 186801|Clostridia P Fe2 transport system protein A feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA JFBFHGED_00895 1158602.I590_02666 1.36e-50 170.0 COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HHV4@91061|Bacilli,4AZF5@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix diphteria tox regulatory element sirR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA JFBFHGED_00896 349741.Amuc_0778 6.09e-215 597.0 2DB8U@1|root,2Z7SW@2|Bacteria,46VFK@74201|Verrucomicrobia,2IUK1@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Alginate lyase - - - - - - - - - - - - Alginate_lyase JFBFHGED_00897 349741.Amuc_0779 1.83e-87 260.0 COG1525@1|root,COG1525@2|Bacteria,46X7M@74201|Verrucomicrobia,2IUVR@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Staphylococcal nuclease homologues - - - - - - - - - - - - SNase JFBFHGED_00899 349741.Amuc_0782 1.46e-113 326.0 COG1475@1|root,COG1475@2|Bacteria,46VTE@74201|Verrucomicrobia 74201|Verrucomicrobia K ParB domain protein nuclease - - - - - - - - - - - - ParBc JFBFHGED_00900 349741.Amuc_0783 2.17e-302 825.0 COG3969@1|root,COG3969@2|Bacteria,46UDX@74201|Verrucomicrobia 74201|Verrucomicrobia S Phosphoadenosine phosphosulfate reductase - - - - - - - - - - - - DUF3440,PAPS_reduct JFBFHGED_00912 1111728.ATYS01000070_gene3490 2.44e-33 127.0 28H9R@1|root,2Z7MD@2|Bacteria,1MVTR@1224|Proteobacteria,1RMPH@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Psort location Cytoplasmic, score 8.96 - - - - - - - - - - - - DUF932 JFBFHGED_00913 509635.N824_14310 2.07e-16 87.0 COG1846@1|root,COG1846@2|Bacteria,4NRCG@976|Bacteroidetes 976|Bacteroidetes K Psort location Cytoplasmic, score - - - - - - - - - - - - - JFBFHGED_00914 1002367.HMPREF0673_00529 8.1e-31 122.0 28JTN@1|root,2Z9IV@2|Bacteria,4NIEW@976|Bacteroidetes,2FQ84@200643|Bacteroidia 976|Bacteroidetes S Psort location Cytoplasmic, score - - - - - - - - - - - - - JFBFHGED_00919 226186.BT_2355 4.63e-148 431.0 COG3392@1|root,COG3392@2|Bacteria,4NJNW@976|Bacteroidetes,2FRYH@200643|Bacteroidia 976|Bacteroidetes H COG3392 Adenine-specific DNA methylase - - 2.1.1.72 ko:K07318 - - - - ko00000,ko01000,ko02048 - - - MethyltransfD12 JFBFHGED_00920 926692.AZYG01000007_gene1229 3.43e-50 196.0 COG0457@1|root,COG3267@1|root,COG3950@1|root,COG0457@2|Bacteria,COG3267@2|Bacteria,COG3950@2|Bacteria,1V5Z6@1239|Firmicutes,24GM8@186801|Clostridia 186801|Clostridia U Tetratricopeptide repeat - - - - - - - - - - - - AAA_16,AAA_22,DUF4062,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8 JFBFHGED_00921 926692.AZYG01000007_gene1230 5.4e-41 148.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - - - - - - - - - - HNH JFBFHGED_00922 1396141.BATP01000001_gene5375 3.39e-89 273.0 COG2887@1|root,COG2887@2|Bacteria,46VRY@74201|Verrucomicrobia,2IVVM@203494|Verrucomicrobiae 203494|Verrucomicrobiae L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 JFBFHGED_00923 1396141.BATP01000001_gene5376 5.08e-35 129.0 2FDAI@1|root,345CE@2|Bacteria,46WE8@74201|Verrucomicrobia,2IVX3@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00924 278957.ABEA03000004_gene4531 6.5e-71 228.0 COG0583@1|root,COG0583@2|Bacteria,46TTX@74201|Verrucomicrobia,3K88B@414999|Opitutae 414999|Opitutae K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate JFBFHGED_00925 1403819.BATR01000127_gene4543 4.92e-107 328.0 COG0845@1|root,COG0845@2|Bacteria,46SB8@74201|Verrucomicrobia,2IU1C@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Biotin-lipoyl like - - - ko:K18094 ko01501,ko02020,map01501,map02020 M00643 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2.21,2.A.6.2.24,8.A.1 - - HlyD,HlyD_D23 JFBFHGED_00926 1396418.BATQ01000098_gene5989 0.0 1234.0 COG0841@1|root,COG0841@2|Bacteria,46SBF@74201|Verrucomicrobia,2IWNC@203494|Verrucomicrobiae 203494|Verrucomicrobiae V AcrB/AcrD/AcrF family - - - ko:K18095 ko01501,ko02020,map01501,map02020 M00643 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2.21,2.A.6.2.24 - - ACR_tran JFBFHGED_00927 290397.Adeh_0516 1e-119 365.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WIRB@28221|Deltaproteobacteria 28221|Deltaproteobacteria M RND efflux system, outer membrane lipoprotein, NodT family - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - OEP JFBFHGED_00928 411471.SUBVAR_07192 3.62e-46 161.0 COG4245@1|root,COG4245@2|Bacteria,1UYN8@1239|Firmicutes,24PQD@186801|Clostridia,3WM02@541000|Ruminococcaceae 186801|Clostridia S von Willebrand factor type A domain - - - - - - - - - - - - VWA JFBFHGED_00929 649831.L083_0250 1.46e-06 59.3 COG0515@1|root,COG0515@2|Bacteria,2GMRN@201174|Actinobacteria,4D9NR@85008|Micromonosporales 201174|Actinobacteria KLT Lanthionine synthetase C-like protein - - - - - - - - - - - - LANC_like,Pkinase JFBFHGED_00932 349741.Amuc_0785 2.43e-263 721.0 COG0473@1|root,COG0473@2|Bacteria,46S4R@74201|Verrucomicrobia,2ITY1@203494|Verrucomicrobiae 203494|Verrucomicrobiae CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh JFBFHGED_00933 349741.Amuc_0786 1.05e-250 687.0 COG0665@1|root,COG0665@2|Bacteria,46VX5@74201|Verrucomicrobia,2IUI6@203494|Verrucomicrobiae 203494|Verrucomicrobiae E FAD dependent oxidoreductase - - - - - - - - - - - - DAO JFBFHGED_00934 349741.Amuc_0787 3.09e-188 525.0 COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Rhomboid family - - - - - - - - - - - - Rhomboid JFBFHGED_00935 349741.Amuc_0788 0.0 929.0 COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia,2ITTW@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Magnesium chelatase, subunit ChlI C-terminal - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C JFBFHGED_00937 349741.Amuc_0790 3.49e-308 840.0 COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae 2|Bacteria E Cys/Met metabolism PLP-dependent enzyme metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP JFBFHGED_00938 349741.Amuc_0791 4.36e-303 826.0 COG0535@1|root,COG0535@2|Bacteria,46T4P@74201|Verrucomicrobia 74201|Verrucomicrobia C SMART Elongator protein 3 MiaB NifB pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM JFBFHGED_00939 349741.Amuc_0792 5.64e-254 696.0 COG0535@1|root,COG0535@2|Bacteria,46T4P@74201|Verrucomicrobia 74201|Verrucomicrobia C SMART Elongator protein 3 MiaB NifB pqqE - - ko:K06139 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM JFBFHGED_00941 349741.Amuc_0794 3.38e-99 288.0 2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia,2IUKT@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00942 349741.Amuc_0795 1.67e-228 630.0 COG0240@1|root,COG0240@2|Bacteria,46SQJ@74201|Verrucomicrobia,2ITRT@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N JFBFHGED_00943 349741.Amuc_0796 6.32e-137 389.0 COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Glycerol-3-phosphate acyltransferase - - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf JFBFHGED_00944 349741.Amuc_0797 5.83e-178 496.0 COG0631@1|root,COG0631@2|Bacteria 2|Bacteria T protein serine/threonine phosphatase activity pppL - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2,SpoIIE JFBFHGED_00945 349741.Amuc_0798 0.0 971.0 COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,2ITHH@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class II (D, K and N) lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon JFBFHGED_00946 349741.Amuc_0799 0.0 2295.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,46UWQ@74201|Verrucomicrobia,2IV57@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,PFOR_II,POR,POR_N,TPP_enzyme_C JFBFHGED_00950 349741.Amuc_0803 0.0 1395.0 COG3507@1|root,COG3934@1|root,COG3507@2|Bacteria,COG3934@2|Bacteria,46XDM@74201|Verrucomicrobia,2IVK0@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Domain of unknown function (DUF4091) - - - - - - - - - - - - DUF4091,F5_F8_type_C JFBFHGED_00951 349741.Amuc_0804 4.79e-174 486.0 COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia,2ITUS@203494|Verrucomicrobiae 203494|Verrucomicrobiae E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF - - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth JFBFHGED_00953 349741.Amuc_0837 4.71e-110 353.0 2DG3X@1|root,2ZUD5@2|Bacteria 2|Bacteria S Carbohydrate esterase, sialic acid-specific acetylesterase - - - - - - - - - - - - SASA JFBFHGED_00954 349741.Amuc_0806 0.0 1088.0 COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia,2IVH0@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Cation transport protein - - - - - - - - - - - - TrkH JFBFHGED_00955 349741.Amuc_0807 2.48e-161 452.0 COG0569@1|root,COG0569@2|Bacteria,46W0A@74201|Verrucomicrobia,2IUXU@203494|Verrucomicrobiae 203494|Verrucomicrobiae P TrkA-N domain - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N JFBFHGED_00956 349741.Amuc_0808 0.0 2328.0 COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,2IU1J@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Oligonucleotide/oligosaccharide-binding (OB)-fold - - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind JFBFHGED_00957 349741.Amuc_0809 4.43e-105 304.0 COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,2IU7V@203494|Verrucomicrobiae 203494|Verrucomicrobiae E ACT domain - - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C JFBFHGED_00958 349741.Amuc_0810 0.0 906.0 COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Trypsin - - - - - - - - - - - - PDZ_2,Trypsin_2 JFBFHGED_00959 349741.Amuc_0811 2.07e-252 695.0 COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta JFBFHGED_00960 349741.Amuc_0812 0.0 1162.0 COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,2ITMA@203494|Verrucomicrobiae 203494|Verrucomicrobiae D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA - - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc JFBFHGED_00961 349741.Amuc_0813 1.29e-225 625.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,46SFQ@74201|Verrucomicrobia,2ITYE@203494|Verrucomicrobiae 203494|Verrucomicrobiae H RibD C-terminal domain - - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 JFBFHGED_00962 349741.Amuc_0814 3.98e-121 355.0 COG1207@1|root,COG1207@2|Bacteria,46Z6P@74201|Verrucomicrobia,2IWPS@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep JFBFHGED_00964 349741.Amuc_0816 9.78e-257 704.0 COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria - - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 JFBFHGED_00966 349741.Amuc_0818 1.51e-207 580.0 COG0499@1|root,COG0499@2|Bacteria 2|Bacteria H adenosylhomocysteinase activity - - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase_NAD,NAD_binding_7,TrkA_N JFBFHGED_00967 349741.Amuc_2152 0.0 2801.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00969 349741.Amuc_0983 3.52e-90 295.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00970 349741.Amuc_0983 4.73e-62 213.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_00971 349741.Amuc_0820 4.18e-162 454.0 COG1376@1|root,COG1376@2|Bacteria,46VEG@74201|Verrucomicrobia,2IUCG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD JFBFHGED_00972 349741.Amuc_0821 5.78e-75 228.0 COG1388@1|root,COG1388@2|Bacteria,46W1D@74201|Verrucomicrobia,2IUXD@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Lysin motif - - - - - - - - - - - - LysM JFBFHGED_00973 349741.Amuc_0822 4.58e-180 503.0 COG0084@1|root,COG0084@2|Bacteria,46SKF@74201|Verrucomicrobia,2IU4S@203494|Verrucomicrobiae 203494|Verrucomicrobiae L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase JFBFHGED_00974 349741.Amuc_0823 5.31e-248 681.0 COG3528@1|root,COG3528@2|Bacteria,46WUE@74201|Verrucomicrobia,2IUWW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Uncharacterized protein conserved in bacteria (DUF2219) - - - - - - - - - - - - DUF2219 JFBFHGED_00975 349741.Amuc_0824 0.0 2516.0 COG3250@1|root,COG3250@2|Bacteria,46XA3@74201|Verrucomicrobia,2IV61@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Beta galactosidase small chain - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N JFBFHGED_00978 243090.RB8895 3.08e-55 206.0 COG4409@1|root,COG4409@2|Bacteria,2IYG9@203682|Planctomycetes 203682|Planctomycetes G BNR repeat-like domain - - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2,BNR_assoc_N JFBFHGED_00979 349741.Amuc_0827 0.0 1023.0 COG0642@1|root,COG2205@2|Bacteria,46UHY@74201|Verrucomicrobia,2ITGS@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Osmosensitive K+ channel His kinase sensor domain - - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,HATPase_c,HisKA,KdpD,Usp JFBFHGED_00980 349741.Amuc_0827 5.84e-209 601.0 COG0642@1|root,COG2205@2|Bacteria,46UHY@74201|Verrucomicrobia,2ITGS@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Osmosensitive K+ channel His kinase sensor domain - - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,HATPase_c,HisKA,KdpD,Usp JFBFHGED_00981 349741.Amuc_0828 1.1e-163 458.0 COG0745@1|root,COG0745@2|Bacteria,46UC4@74201|Verrucomicrobia,2IUBT@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Transcriptional regulatory protein, C terminal - - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C JFBFHGED_00983 349741.Amuc_0830 0.0 1011.0 COG2060@1|root,COG2060@2|Bacteria,46S9Y@74201|Verrucomicrobia,2ITVE@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane - - 3.6.3.12 ko:K01546 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - KdpA JFBFHGED_00984 349741.Amuc_0831 0.0 1209.0 COG2216@1|root,COG2216@2|Bacteria,46SEM@74201|Verrucomicrobia,2ITIQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system - - 3.6.3.12 ko:K01547 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - E1-E2_ATPase,Hydrolase JFBFHGED_00985 349741.Amuc_0832 9.88e-105 305.0 COG2156@1|root,COG2156@2|Bacteria,46SYC@74201|Verrucomicrobia,2IVFX@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex - - 3.6.3.12 ko:K01548 ko02020,map02020 - - - ko00000,ko00001,ko01000 3.A.3.7 - - KdpC JFBFHGED_00986 349741.Amuc_1187 4.92e-205 587.0 COG1501@1|root,COG1501@2|Bacteria,46UJE@74201|Verrucomicrobia,2IUGJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha galactosidase A - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - He_PIG_assoc,Melibiase_2 JFBFHGED_00987 349741.Amuc_0836 0.0 1558.0 COG0542@1|root,COG0542@2|Bacteria,46S4S@74201|Verrucomicrobia,2ITN7@203494|Verrucomicrobiae 203494|Verrucomicrobiae O C-terminal, D2-small domain, of ClpB protein - - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N JFBFHGED_00991 349741.Amuc_0837 0.0 890.0 2DG3X@1|root,2ZUD5@2|Bacteria 2|Bacteria S Carbohydrate esterase, sialic acid-specific acetylesterase - - - - - - - - - - - - SASA JFBFHGED_00992 349741.Amuc_0838 1.04e-109 316.0 COG1327@1|root,COG1327@2|Bacteria,46TAA@74201|Verrucomicrobia,2IU77@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone JFBFHGED_00993 349741.Amuc_0839 1.69e-114 329.0 28XDJ@1|root,2ZJBA@2|Bacteria,46WSJ@74201|Verrucomicrobia,2IUQ4@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_00994 644282.Deba_0261 3.23e-26 111.0 COG0778@1|root,COG1146@1|root,COG0778@2|Bacteria,COG1146@2|Bacteria,1R42D@1224|Proteobacteria,42Q57@68525|delta/epsilon subdivisions,2WNIW@28221|Deltaproteobacteria 28221|Deltaproteobacteria C 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_4,Fer4_7,Fer4_9,Nitroreductase JFBFHGED_00995 1151292.QEW_3987 3.1e-42 141.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia 186801|Clostridia K transcriptional regulator hxlR - - - - - - - - - - - HxlR JFBFHGED_00996 349741.Amuc_0840 0.0 1020.0 COG0659@1|root,COG0659@2|Bacteria,46UA5@74201|Verrucomicrobia,2IWMC@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Sulfate permease family - - - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp JFBFHGED_00997 349741.Amuc_0841 0.0 867.0 COG0165@1|root,COG0165@2|Bacteria,46SCX@74201|Verrucomicrobia,2ITKH@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Argininosuccinate lyase C-terminal argH - 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 JFBFHGED_00998 316067.Geob_1221 2.49e-175 501.0 COG1672@1|root,COG1672@2|Bacteria,1MWQD@1224|Proteobacteria 1224|Proteobacteria S ATPase (AAA) - - - - - - - - - - - - AAA_16 JFBFHGED_00999 349741.Amuc_0842 7.89e-147 415.0 COG4279@1|root,COG4279@2|Bacteria,46V8E@74201|Verrucomicrobia,2IUH9@203494|Verrucomicrobiae 203494|Verrucomicrobiae S SWIM zinc finger - - - - - - - - - - - - SWIM JFBFHGED_01000 349741.Amuc_0843 4.51e-280 775.0 2BTJC@1|root,32NRX@2|Bacteria,46XRE@74201|Verrucomicrobia,2IWF2@203494|Verrucomicrobiae 349741.Amuc_0843|- - - - - - - - - - - - - - - - JFBFHGED_01001 349741.Amuc_0844 3.58e-300 820.0 COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,2ITUV@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N JFBFHGED_01002 349741.Amuc_0845 6.73e-183 512.0 COG0648@1|root,COG0648@2|Bacteria,46VWJ@74201|Verrucomicrobia 74201|Verrucomicrobia L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 JFBFHGED_01003 596152.DesU5LDRAFT_1709 6.03e-24 95.1 COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MC8X@213115|Desulfovibrionales 28221|Deltaproteobacteria K SMART regulatory protein ArsR - - - - - - - - - - - - HTH_20,HTH_5 JFBFHGED_01004 1121344.JHZO01000004_gene1484 2.45e-14 72.8 COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,3WKWC@541000|Ruminococcaceae 186801|Clostridia CO redox-active disulfide protein 2 - - - - - - - - - - - - Thioredoxin_3 JFBFHGED_01005 709991.Odosp_3362 3.84e-161 459.0 COG0701@1|root,COG0701@2|Bacteria,4NDUJ@976|Bacteroidetes,2FNF8@200643|Bacteroidia,22XMI@171551|Porphyromonadaceae 976|Bacteroidetes P Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 JFBFHGED_01006 349741.Amuc_0846 0.0 1296.0 COG3669@1|root,COG3669@2|Bacteria,46TW6@74201|Verrucomicrobia,2IVJY@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,F5_F8_type_C JFBFHGED_01007 349741.Amuc_0847 1.08e-247 681.0 COG3481@1|root,COG3481@2|Bacteria,46SYB@74201|Verrucomicrobia,2ITKE@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD JFBFHGED_01008 349741.Amuc_0848 0.0 1134.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,46T3W@74201|Verrucomicrobia,2IUFR@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Competence protein - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B JFBFHGED_01009 349741.Amuc_0849 0.0 879.0 COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia,2ITRH@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 JFBFHGED_01010 118166.JH976537_gene3811 9.67e-73 224.0 arCOG13037@1|root,3342X@2|Bacteria,1GH1X@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - JFBFHGED_01011 349741.Amuc_0850 7.67e-293 799.0 COG2265@1|root,COG2265@2|Bacteria,46SYJ@74201|Verrucomicrobia,2ITST@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA (Uracil-5-)-methyltransferase - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr JFBFHGED_01013 1184267.A11Q_2436 4.43e-85 263.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,42QRB@68525|delta/epsilon subdivisions,2MSX5@213481|Bdellovibrionales,2WMSD@28221|Deltaproteobacteria 213481|Bdellovibrionales S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 JFBFHGED_01015 349741.Amuc_0853 2.92e-313 858.0 2BTJH@1|root,32NS3@2|Bacteria,46XQC@74201|Verrucomicrobia,2IWD7@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01016 349741.Amuc_0854 8.29e-43 141.0 COG0776@1|root,COG0776@2|Bacteria 2|Bacteria L regulation of translation himA - - ko:K03530,ko:K04764,ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding JFBFHGED_01017 349741.Amuc_0855 0.0 1311.0 COG3345@1|root,COG3345@2|Bacteria,46UG8@74201|Verrucomicrobia,2IVJR@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 36 N-terminal domain - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase JFBFHGED_01018 349741.Amuc_0856 0.0 989.0 COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,46YYG@74201|Verrucomicrobia,2IU9A@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Predicted Permease Membrane Region - - - ko:K07085 - - - - ko00000 2.A.81 - - Asp-Al_Ex,TrkA_C JFBFHGED_01019 349741.Amuc_0860 2.19e-130 375.0 COG1180@1|root,COG1180@2|Bacteria,46W66@74201|Verrucomicrobia,2IVWH@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Radical SAM superfamily - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM JFBFHGED_01020 349741.Amuc_0861 3.8e-43 140.0 COG1328@1|root,COG1328@2|Bacteria 2|Bacteria F CTP reductase activity nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,Glutaredoxin,NRDD JFBFHGED_01021 349741.Amuc_0862 0.0 1395.0 COG1328@1|root,COG1328@2|Bacteria,46TE5@74201|Verrucomicrobia,2IV27@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Anaerobic ribonucleoside-triphosphate reductase - - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - NRDD JFBFHGED_01022 349741.Amuc_0863 0.0 1395.0 COG4225@1|root,COG4225@2|Bacteria,46UYE@74201|Verrucomicrobia,2IVRC@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl Hydrolase Family 88 - - - - - - - - - - - - Glyco_hydro_88 JFBFHGED_01023 349741.Amuc_0864 0.0 1000.0 COG2194@1|root,COG2194@2|Bacteria,46XK1@74201|Verrucomicrobia,2IW42@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF1705) - - - - - - - - - - - - DUF1705,Sulfatase JFBFHGED_01025 349741.Amuc_0865 7.65e-119 340.0 COG1592@1|root,COG1592@2|Bacteria 2|Bacteria C Rubrerythrin ngr - - - - - - - - - - - Flavin_Reduct,Rubrerythrin JFBFHGED_01027 349741.Amuc_0867 9.1e-261 716.0 COG1363@1|root,COG1363@2|Bacteria,46XAY@74201|Verrucomicrobia,2IV87@203494|Verrucomicrobiae 203494|Verrucomicrobiae G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 JFBFHGED_01028 349741.Amuc_0868 0.0 991.0 COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_01029 349741.Amuc_0869 4.13e-274 751.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 JFBFHGED_01030 349741.Amuc_0870 5.16e-251 691.0 COG1785@1|root,COG1785@2|Bacteria,46X6X@74201|Verrucomicrobia,2IUSG@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Alkaline phosphatase homologues - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Alk_phosphatase JFBFHGED_01031 349741.Amuc_0871 1.4e-81 243.0 COG1970@1|root,COG1970@2|Bacteria,46VW8@74201|Verrucomicrobia,2IUX6@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Large-conductance mechanosensitive channel, MscL - - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL JFBFHGED_01032 349741.Amuc_0872 3.33e-304 829.0 COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,2ITW4@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class-III - - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 JFBFHGED_01033 349741.Amuc_0873 3.72e-100 291.0 COG4747@1|root,COG4747@2|Bacteria,46SXP@74201|Verrucomicrobia,2IUP5@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ACT domain protein - - - - - - - - - - - - - JFBFHGED_01034 349741.Amuc_0874 2.19e-130 370.0 COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia,2IU7M@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Elongation factor P (EF-P) OB domain - - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C JFBFHGED_01035 1403819.BATR01000104_gene3548 2.61e-46 159.0 COG2755@1|root,COG2755@2|Bacteria,46XFP@74201|Verrucomicrobia,2IVSE@203494|Verrucomicrobiae 203494|Verrucomicrobiae E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 JFBFHGED_01036 349741.Amuc_0875 4.96e-228 628.0 COG2273@1|root,COG2273@2|Bacteria,46XEF@74201|Verrucomicrobia,2IVNG@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolases family 16 - - - - - - - - - - - - Glyco_hydro_16 JFBFHGED_01037 349741.Amuc_0876 0.0 1311.0 COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,2ITMQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae P E1-E2 ATPase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS JFBFHGED_01038 349741.Amuc_0877 0.0 1003.0 COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia,2IU0W@203494|Verrucomicrobiae 203494|Verrucomicrobiae L RecF/RecN/SMC N terminal domain - - - ko:K03631 - - - - ko00000,ko03400 - - - SMC_N JFBFHGED_01039 349741.Amuc_0878 8.87e-173 483.0 COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia,2IU7C@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Metallo-beta-lactamase superfamily - - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 JFBFHGED_01040 349741.Amuc_0879 2.79e-164 462.0 COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase WecB/TagA/CpsF family - - - - - - - - - - - - Glyco_tran_WecB JFBFHGED_01041 349741.Amuc_0880 8.18e-135 385.0 COG2315@1|root,COG2315@2|Bacteria 2|Bacteria V Protein conserved in bacteria yyaQ - - - - - - - - - - - YjbR JFBFHGED_01042 349741.Amuc_0881 9.99e-76 228.0 2DTWY@1|root,33N1Q@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - C_GCAxxG_C_C JFBFHGED_01045 349741.Amuc_0884 1.95e-189 528.0 COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia,2IU0K@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF1009) - - - ko:K09949 - - - - ko00000 - - - DUF1009 JFBFHGED_01046 349741.Amuc_0885 1.01e-292 800.0 COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia,2ITVD@203494|Verrucomicrobiae 203494|Verrucomicrobiae C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding JFBFHGED_01047 349741.Amuc_0886 2.5e-231 637.0 COG0022@1|root,COG0022@2|Bacteria,46UID@74201|Verrucomicrobia,2ITK5@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Transketolase, pyrimidine binding domain - - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C JFBFHGED_01048 349741.Amuc_0887 4.23e-217 600.0 COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia,2ITWI@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Dehydrogenase E1 component - - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh JFBFHGED_01049 349741.Amuc_0888 6.43e-159 449.0 COG0789@1|root,COG0789@2|Bacteria 2|Bacteria K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - - - - - - - - - - Cass2,GyrI-like,MerR_1 JFBFHGED_01050 349741.Amuc_0889 7.8e-215 600.0 COG0845@1|root,COG0845@2|Bacteria,46SB8@74201|Verrucomicrobia,2IU1C@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Biotin-lipoyl like - - - ko:K18094 ko01501,ko02020,map01501,map02020 M00643 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2.21,2.A.6.2.24,8.A.1 - - HlyD,HlyD_D23 JFBFHGED_01051 349741.Amuc_0890 0.0 1850.0 COG0841@1|root,COG0841@2|Bacteria,46SBF@74201|Verrucomicrobia,2IWNC@203494|Verrucomicrobiae 203494|Verrucomicrobiae V AcrB/AcrD/AcrF family - - - ko:K18095 ko01501,ko02020,map01501,map02020 M00643 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2.21,2.A.6.2.24 - - ACR_tran JFBFHGED_01052 349741.Amuc_0894 1.78e-163 459.0 COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 JFBFHGED_01053 349741.Amuc_0895 1.5e-90 266.0 COG3212@1|root,COG3212@2|Bacteria,46WQF@74201|Verrucomicrobia 74201|Verrucomicrobia S peptidase - - - - - - - - - - - - PepSY_like JFBFHGED_01054 349741.Amuc_0896 0.0 932.0 COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia,2ITRR@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Uroporphyrinogen-III synthase HemD - - 2.1.1.107,4.2.1.75 ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165,R03194 RC00003,RC00871,RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4,TP_methylase JFBFHGED_01055 349741.Amuc_0897 2.01e-89 263.0 2F8IJ@1|root,340XC@2|Bacteria,46WTZ@74201|Verrucomicrobia,2IUYP@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01056 349741.Amuc_0898 0.0 1587.0 COG0550@1|root,COG0550@2|Bacteria,46S97@74201|Verrucomicrobia,2ITTZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Bacterial DNA topoisomeraes I ATP-binding domain - - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt JFBFHGED_01058 1507.HMPREF0262_03326 4.99e-112 334.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,36DI6@31979|Clostridiaceae 186801|Clostridia K aldo keto reductase - - - - - - - - - - - - Aldo_ket_red JFBFHGED_01059 349741.Amuc_0903 9.11e-162 452.0 COG5632@1|root,COG5632@2|Bacteria,46VKP@74201|Verrucomicrobia,2IU5K@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 JFBFHGED_01060 349741.Amuc_0904 0.0 1741.0 COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,2ITHS@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Aconitase C-terminal domain - - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C JFBFHGED_01061 1687.BCOR_0161 0.000146 45.4 2AYY7@1|root,31R41@2|Bacteria,2GX2D@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - JFBFHGED_01062 639030.JHVA01000001_gene2076 1.39e-12 67.0 2BT4J@1|root,32N96@2|Bacteria,3Y60Q@57723|Acidobacteria,2JK58@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF2752) - - - - - - - - - - - - DUF2752 JFBFHGED_01063 349741.Amuc_0905 5.81e-122 349.0 COG1376@1|root,COG1376@2|Bacteria 2|Bacteria D ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - Ank_2,YkuD JFBFHGED_01064 349741.Amuc_0906 2.4e-257 707.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,46SSF@74201|Verrucomicrobia,2IU9E@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR JFBFHGED_01066 349741.Amuc_0908 0.0 1389.0 COG4166@1|root,COG4166@2|Bacteria 2|Bacteria E transmembrane transport - - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BACON,M60-like_N,Peptidase_M60,SBP_bac_5 JFBFHGED_01067 349741.Amuc_0909 2.44e-252 695.0 COG1690@1|root,COG1690@2|Bacteria,46STD@74201|Verrucomicrobia,2IUZX@203494|Verrucomicrobiae 203494|Verrucomicrobiae S tRNA-splicing ligase RtcB - - - - - - - - - - - - RtcB JFBFHGED_01068 349741.Amuc_0910 9.66e-199 553.0 COG0583@1|root,COG0583@2|Bacteria,46V82@74201|Verrucomicrobia,2IVST@203494|Verrucomicrobiae 203494|Verrucomicrobiae K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate JFBFHGED_01069 349741.Amuc_0911 9.53e-284 776.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr JFBFHGED_01070 349741.Amuc_0913 7.33e-119 341.0 COG2096@1|root,COG2096@2|Bacteria,46T1G@74201|Verrucomicrobia,2IUKY@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Cobalamin adenosyltransferase - - - - - - - - - - - - Cob_adeno_trans JFBFHGED_01072 349741.Amuc_1143 3.74e-116 379.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_01073 349741.Amuc_2039 8.33e-23 97.8 COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae 203494|Verrucomicrobiae E LeuA allosteric (dimerisation) domain - - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer JFBFHGED_01075 349741.Amuc_1143 0.0 1394.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_01077 1396141.BATP01000027_gene1074 6.87e-226 734.0 COG2373@1|root,COG2373@2|Bacteria,46U44@74201|Verrucomicrobia,2IV8F@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Alpha-2-macroglobulin MG1 domain - - - - - - - - - - - - A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl JFBFHGED_01078 1396141.BATP01000027_gene1075 2.56e-186 556.0 COG4953@1|root,COG4953@2|Bacteria,46TMS@74201|Verrucomicrobia,2IV2J@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Transglycosylase - - - - - - - - - - - - Transgly,Transpeptidase JFBFHGED_01079 349741.Amuc_0914 1.22e-70 213.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 JFBFHGED_01080 349741.Amuc_0915 0.0 1345.0 COG0557@1|root,COG0557@2|Bacteria,46U8T@74201|Verrucomicrobia,2ITHQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 JFBFHGED_01081 349741.Amuc_0917 0.0 1512.0 COG0826@1|root,COG0826@2|Bacteria,46UGV@74201|Verrucomicrobia,2ITKP@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Collagenase - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF3656,Peptidase_U32 JFBFHGED_01082 349741.Amuc_0918 7.11e-260 716.0 COG0285@1|root,COG0285@2|Bacteria,46SKD@74201|Verrucomicrobia,2ITNW@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Mur ligase middle domain - - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M JFBFHGED_01084 349741.Amuc_0920 0.0 914.0 COG0673@1|root,COG0673@2|Bacteria,46U7B@74201|Verrucomicrobia,2IV4V@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA JFBFHGED_01088 349741.Amuc_0921 0.0 1599.0 COG0553@1|root,COG0553@2|Bacteria,46U9A@74201|Verrucomicrobia,2ITYK@203494|Verrucomicrobiae 203494|Verrucomicrobiae L SNF2 Helicase protein - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - DUF3670,Helicase_C,SNF2_N JFBFHGED_01089 349741.Amuc_0922 5.08e-291 800.0 COG0737@1|root,COG0737@2|Bacteria,46X8F@74201|Verrucomicrobia,2IV06@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Calcineurin-like phosphoesterase - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos JFBFHGED_01090 349741.Amuc_0923 2.13e-107 311.0 COG0797@1|root,COG0797@2|Bacteria,46WTP@74201|Verrucomicrobia,2IUW1@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Lytic transglycolase - - - ko:K03642 - - - - ko00000 - - - DPBB_1 JFBFHGED_01091 349741.Amuc_0924 4.14e-199 553.0 COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,2IUD8@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - CTP_transf_like,NAD_kinase JFBFHGED_01092 349741.Amuc_0925 4.38e-47 150.0 COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal proteins 50S L24/mitochondrial 39S L24 rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 JFBFHGED_01093 349741.Amuc_0926 3.63e-136 385.0 COG0094@1|root,COG0094@2|Bacteria,46SP7@74201|Verrucomicrobia,2ITU8@203494|Verrucomicrobiae 203494|Verrucomicrobiae J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE - - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C JFBFHGED_01094 349741.Amuc_0927 9.62e-87 255.0 COG0096@1|root,COG0096@2|Bacteria,46T2K@74201|Verrucomicrobia,2IUCT@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH - - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 JFBFHGED_01095 349741.Amuc_0928 2.63e-104 303.0 COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,2IU69@203494|Verrucomicrobiae 203494|Verrucomicrobiae J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF - - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 JFBFHGED_01096 349741.Amuc_0929 5.39e-71 214.0 COG0256@1|root,COG0256@2|Bacteria,46T7Z@74201|Verrucomicrobia,2IUJF@203494|Verrucomicrobiae 203494|Verrucomicrobiae J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR - - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p JFBFHGED_01097 349741.Amuc_0930 3.8e-102 299.0 COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia,2IUC7@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C JFBFHGED_01098 349741.Amuc_0931 6.17e-99 288.0 COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia,2IUE6@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A rplO - - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A JFBFHGED_01100 349741.Amuc_0933 0.0 922.0 COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,2ITRX@203494|Verrucomicrobiae 203494|Verrucomicrobiae U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY JFBFHGED_01101 349741.Amuc_0934 1.75e-143 405.0 COG0563@1|root,COG0563@2|Bacteria,46YYW@74201|Verrucomicrobia,2IUVY@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK JFBFHGED_01102 349741.Amuc_0935 7.18e-190 527.0 COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia,2ITSS@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Metallopeptidase family M24 map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 JFBFHGED_01103 349741.Amuc_0936 3.48e-245 674.0 COG4763@1|root,COG4763@2|Bacteria 2|Bacteria S transferase activity, transferring acyl groups other than amino-acyl groups - - - ko:K11941 - - - - ko00000,ko01000 - - - Acyl_transf_3 JFBFHGED_01104 349741.Amuc_0937 0.0 979.0 COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,46YY5@74201|Verrucomicrobia,2ITTR@203494|Verrucomicrobiae 203494|Verrucomicrobiae FP Ppx/GppA phosphatase family - - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA JFBFHGED_01105 349741.Amuc_0938 0.0 1326.0 COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia,2ITZT@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Polyphosphate kinase middle domain - - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N JFBFHGED_01106 349741.Amuc_0599 1.34e-70 236.0 COG3746@1|root,COG3746@2|Bacteria,46T78@74201|Verrucomicrobia,2IUW9@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Phosphate-selective porin O and P - - - ko:K07221 - - - - ko00000,ko02000 1.B.5.1 - - Porin_O_P JFBFHGED_01107 714943.Mucpa_6737 3.9e-101 355.0 COG1629@1|root,COG4676@1|root,COG4783@1|root,COG1629@2|Bacteria,COG4676@2|Bacteria,COG4783@2|Bacteria,4NGJS@976|Bacteroidetes,1J199@117747|Sphingobacteriia 976|Bacteroidetes P Vault protein inter-alpha-trypsin domain - - - - - - - - - - - - CarbopepD_reg_2,DUF2135,Plug,VIT JFBFHGED_01108 349741.Amuc_0939 1.14e-73 240.0 COG1442@1|root,COG1442@2|Bacteria,46WTH@74201|Verrucomicrobia 74201|Verrucomicrobia H PFAM glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 JFBFHGED_01109 349741.Amuc_0939 2.4e-100 308.0 COG1442@1|root,COG1442@2|Bacteria,46WTH@74201|Verrucomicrobia 74201|Verrucomicrobia H PFAM glycosyl transferase family 8 - - - - - - - - - - - - Glyco_transf_8 JFBFHGED_01110 349741.Amuc_0945 4.09e-91 284.0 COG1216@1|root,COG1216@2|Bacteria,46W1P@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01111 349741.Amuc_0945 3.44e-80 256.0 COG1216@1|root,COG1216@2|Bacteria,46W1P@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01112 349741.Amuc_0945 2.93e-95 295.0 COG1216@1|root,COG1216@2|Bacteria,46W1P@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01113 349741.Amuc_0945 2.37e-177 503.0 COG1216@1|root,COG1216@2|Bacteria,46W1P@74201|Verrucomicrobia 74201|Verrucomicrobia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01114 349741.Amuc_0946 3.48e-122 349.0 COG0693@1|root,COG0693@2|Bacteria,46Z1W@74201|Verrucomicrobia,2IUW2@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DJ-1/PfpI family - - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI JFBFHGED_01115 349741.Amuc_0947 1.95e-214 596.0 COG0508@1|root,COG0508@2|Bacteria,46SHZ@74201|Verrucomicrobia,2IU2H@203494|Verrucomicrobiae 203494|Verrucomicrobiae C e3 binding domain - - - - - - - - - - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding JFBFHGED_01116 349741.Amuc_0948 1.1e-277 759.0 COG1820@1|root,COG1820@2|Bacteria,46SRF@74201|Verrucomicrobia,2IU36@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Belongs to the metallo-dependent hydrolases superfamily. NagA family - - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 JFBFHGED_01118 349741.Amuc_0949 9.42e-125 357.0 COG0652@1|root,COG0652@2|Bacteria,46V73@74201|Verrucomicrobia,2IU91@203494|Verrucomicrobiae 203494|Verrucomicrobiae O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase JFBFHGED_01119 349741.Amuc_0950 1.43e-306 837.0 COG0477@1|root,COG2814@2|Bacteria,46VGN@74201|Verrucomicrobia,2ITZY@203494|Verrucomicrobiae 203494|Verrucomicrobiae EGIP Phosphate acyltransferases - - - - - - - - - - - - Acyltransferase,MFS_1 JFBFHGED_01120 349741.Amuc_0951 0.0 900.0 COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia,2IU78@203494|Verrucomicrobiae 203494|Verrucomicrobiae T 5TM C-terminal transporter carbon starvation CstA - - - - - - - - - - - - CstA,CstA_5TM JFBFHGED_01121 349741.Amuc_0952 2.86e-121 352.0 2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae 349741.Amuc_0952|- - - - - - - - - - - - - - - - JFBFHGED_01122 349741.Amuc_0953 0.0 1997.0 COG3119@1|root,COG3119@2|Bacteria,46UIA@74201|Verrucomicrobia,2IVFY@203494|Verrucomicrobiae 203494|Verrucomicrobiae P PA14 domain - - - - - - - - - - - - PA14,Sulfatase JFBFHGED_01123 349741.Amuc_0955 4.35e-77 230.0 COG0858@1|root,COG0858@2|Bacteria,46TBI@74201|Verrucomicrobia,2IUMI@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA JFBFHGED_01124 349741.Amuc_0956 0.0 1212.0 COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,2ITNN@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N JFBFHGED_01125 349741.Amuc_0957 5.33e-287 786.0 COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia,2ITT2@203494|Verrucomicrobiae 203494|Verrucomicrobiae K NusA-like KH domain nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 JFBFHGED_01126 349741.Amuc_0958 4.51e-187 519.0 COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,2IU1A@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Endonuclease/Exonuclease/phosphatase family - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos JFBFHGED_01127 349741.Amuc_0959 9.55e-138 390.0 COG0127@1|root,COG0127@2|Bacteria,46SZ5@74201|Verrucomicrobia,2IU83@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like JFBFHGED_01128 349741.Amuc_0960 2.95e-126 362.0 COG2519@1|root,COG2519@2|Bacteria,46VQ7@74201|Verrucomicrobia,2IUKX@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Putative rRNA methylase - - - - - - - - - - - - rRNA_methylase JFBFHGED_01129 349741.Amuc_0961 6.58e-198 550.0 COG2006@1|root,COG2006@2|Bacteria,46U2P@74201|Verrucomicrobia 74201|Verrucomicrobia S Domain of unknown function (DUF362) - - - - - - - - - - - - DUF362 JFBFHGED_01130 349741.Amuc_0962 0.0 1063.0 COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,46UPW@74201|Verrucomicrobia 74201|Verrucomicrobia C PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_5,Fer4_7 JFBFHGED_01132 203119.Cthe_1243 8.24e-34 123.0 COG0454@1|root,COG0454@2|Bacteria,1UID4@1239|Firmicutes,25EI4@186801|Clostridia,3WSIR@541000|Ruminococcaceae 186801|Clostridia K FR47-like protein - - - - - - - - - - - - Acetyltransf_10 JFBFHGED_01134 349741.Amuc_0963 0.0 1073.0 COG1131@1|root,COG1668@1|root,COG1131@2|Bacteria,COG1668@2|Bacteria,46SII@74201|Verrucomicrobia,2ITQM@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane,ABC_tran JFBFHGED_01136 349741.Amuc_0965 0.0 1139.0 2BZ41@1|root,2ZDAE@2|Bacteria,46SM4@74201|Verrucomicrobia,2ITI9@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01137 349741.Amuc_0966 1.55e-179 499.0 COG3786@1|root,COG3786@2|Bacteria,46STB@74201|Verrucomicrobia,2IUPE@203494|Verrucomicrobiae 203494|Verrucomicrobiae S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD JFBFHGED_01138 349741.Amuc_0967 9.78e-132 376.0 COG0724@1|root,COG0724@2|Bacteria,46WD6@74201|Verrucomicrobia,2IUKQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S RNA recognition motif - - - - - - - - - - - - RRM_1 JFBFHGED_01139 349741.Amuc_0968 3.58e-301 825.0 COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia,2ITYD@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf JFBFHGED_01140 349741.Amuc_0969 1.16e-279 765.0 COG0153@1|root,COG0153@2|Bacteria,46V7W@74201|Verrucomicrobia,2IU6C@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Galactokinase galactose-binding signature - - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg JFBFHGED_01141 349741.Amuc_0970 0.0 1360.0 COG4146@1|root,COG4146@2|Bacteria,46UV3@74201|Verrucomicrobia,2ITNB@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Sodium:solute symporter family - - - ko:K03307 - - - - ko00000 2.A.21 - - SSF JFBFHGED_01143 349741.Amuc_0971 0.0 1286.0 COG0210@1|root,COG0210@2|Bacteria,46THX@74201|Verrucomicrobia,2ITGV@203494|Verrucomicrobiae 203494|Verrucomicrobiae L UvrD-like helicase C-terminal domain - - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C JFBFHGED_01144 349741.Amuc_0972 8.18e-216 597.0 COG0223@1|root,COG0223@2|Bacteria,46SKS@74201|Verrucomicrobia,2ITWX@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N JFBFHGED_01145 349741.Amuc_0973 4.94e-118 349.0 COG0707@1|root,COG0707@2|Bacteria,46SK7@74201|Verrucomicrobia,2IU5J@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Monogalactosyldiacylglycerol (MGDG) synthase - - - - - - - - - - - - MGDG_synth JFBFHGED_01146 349741.Amuc_0973 1.13e-62 202.0 COG0707@1|root,COG0707@2|Bacteria,46SK7@74201|Verrucomicrobia,2IU5J@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Monogalactosyldiacylglycerol (MGDG) synthase - - - - - - - - - - - - MGDG_synth JFBFHGED_01147 349741.Amuc_0974 3.93e-162 455.0 COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia,2IU5A@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Type III pantothenate kinase coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase JFBFHGED_01148 349741.Amuc_0975 3.49e-44 144.0 COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia,2IUTD@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ Phosphopantetheine attachment site acpP - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding JFBFHGED_01149 349741.Amuc_0976 2.92e-124 354.0 2CNXM@1|root,32SI1@2|Bacteria,46SZC@74201|Verrucomicrobia,2IUHE@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01150 349741.Amuc_0977 5.63e-157 442.0 COG1376@1|root,COG1376@2|Bacteria,46W0P@74201|Verrucomicrobia,2IURM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Lysin motif - - - - - - - - - - - - LysM JFBFHGED_01151 349741.Amuc_0978 3.17e-91 268.0 COG1490@1|root,COG1490@2|Bacteria,46STH@74201|Verrucomicrobia,2IUCY@203494|Verrucomicrobiae 203494|Verrucomicrobiae J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd - - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase JFBFHGED_01152 349741.Amuc_0984 9.39e-181 503.0 COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,2ITQJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae C 2Fe-2S iron-sulfur cluster binding domain - - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 JFBFHGED_01153 349741.Amuc_0985 0.0 1302.0 COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,2ITUA@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C JFBFHGED_01154 349741.Amuc_0986 3.65e-158 444.0 2CAZH@1|root,2Z7RU@2|Bacteria,46SY1@74201|Verrucomicrobia,2IUAR@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt JFBFHGED_01155 349741.Amuc_0987 1.96e-50 160.0 2E5PI@1|root,330E7@2|Bacteria,46W49@74201|Verrucomicrobia,2IUXC@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01156 349741.Amuc_0988 2.85e-185 515.0 COG1099@1|root,COG1099@2|Bacteria,46TUW@74201|Verrucomicrobia,2ITR8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S TatD related DNase - - - ko:K07051 - - - - ko00000 - - - TatD_DNase JFBFHGED_01157 349741.Amuc_0989 2.82e-44 144.0 COG3339@1|root,COG3339@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1232) XK27_09985 - - - - - - - - - - - DUF1232 JFBFHGED_01159 349741.Amuc_0952 8.67e-06 53.9 2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae 349741.Amuc_0952|- - - - - - - - - - - - - - - - JFBFHGED_01160 411476.BACOVA_03771 5.5e-99 293.0 COG3153@1|root,COG3153@2|Bacteria,4NJED@976|Bacteroidetes,2G3BG@200643|Bacteroidia,4AWD2@815|Bacteroidaceae 976|Bacteroidetes S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_7 JFBFHGED_01161 349741.Amuc_0993 1.37e-254 701.0 COG1262@1|root,COG1262@2|Bacteria,46UX3@74201|Verrucomicrobia,2ITQQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase,PSCyt1 JFBFHGED_01162 349741.Amuc_0994 5.15e-167 469.0 COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2ITSE@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 JFBFHGED_01164 349741.Amuc_0996 0.0 934.0 COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia,2IWNF@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn JFBFHGED_01165 1565314.OA34_11780 2.75e-08 60.1 COG4238@1|root,COG4238@2|Bacteria,1N4E5@1224|Proteobacteria,42USX@68525|delta/epsilon subdivisions,2YQ09@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria M major outer membrane lipoprotein - - - - - - - - - - - - - JFBFHGED_01167 349741.Amuc_0999 1.41e-135 384.0 COG1544@1|root,COG1544@2|Bacteria,46VGU@74201|Verrucomicrobia,2IU7I@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Sigma 54 modulation/S30EA ribosomal protein C terminus - - - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE JFBFHGED_01169 349741.Amuc_1008 0.0 2427.0 COG1501@1|root,COG1501@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - DUF4968,DUF5110,F5_F8_type_C,FIVAR,Gal_mutarotas_2,Glyco_hydro_31,NPCBM,NPCBM_assoc JFBFHGED_01170 349741.Amuc_1009 1.26e-253 702.0 COG0348@1|root,COG0348@2|Bacteria 2|Bacteria C 4 iron, 4 sulfur cluster binding - - - - - - - - - - - - Fer4,Fer4_5,Fer4_9 JFBFHGED_01171 314278.NB231_05411 4.19e-36 148.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1WX3J@135613|Chromatiales 135613|Chromatiales H Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate cysI - 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr JFBFHGED_01174 1235803.C825_02118 7.91e-135 387.0 COG0637@1|root,COG0637@2|Bacteria,4NIYB@976|Bacteroidetes,2FM33@200643|Bacteroidia,22WA4@171551|Porphyromonadaceae 976|Bacteroidetes S Belongs to the HAD-like hydrolase superfamily. PhnX family phnX - 3.11.1.1 ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R00747 RC00368 ko00000,ko00001,ko01000 - - - HAD_2 JFBFHGED_01175 880526.KE386488_gene535 1.77e-199 560.0 COG0075@1|root,COG0075@2|Bacteria,4NH61@976|Bacteroidetes,2FP5I@200643|Bacteroidia 976|Bacteroidetes E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily phnW - 2.6.1.37 ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 - R04152 RC00008,RC00062 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_5 JFBFHGED_01176 658086.HMPREF0994_05045 1.67e-134 386.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,249SV@186801|Clostridia,27QT9@186928|unclassified Lachnospiraceae 186801|Clostridia E ATPases associated with a variety of cellular activities - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran JFBFHGED_01177 411490.ANACAC_03504 6.13e-207 593.0 COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,24A64@186801|Clostridia 186801|Clostridia P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 JFBFHGED_01178 658086.HMPREF0994_05043 1.69e-123 364.0 COG1840@1|root,COG1840@2|Bacteria,1TT3Y@1239|Firmicutes,24AJP@186801|Clostridia 186801|Clostridia P Bacterial extracellular solute-binding protein - - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1,SBP_bac_6 JFBFHGED_01179 349741.Amuc_1010 5.76e-97 283.0 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg JFBFHGED_01181 349741.Amuc_1011 1.82e-159 451.0 2CIFR@1|root,2Z835@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2589) - - - - - - - - - - - - DUF2589 JFBFHGED_01182 349741.Amuc_1012 2.54e-148 422.0 2BZAR@1|root,32V3N@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_01183 349741.Amuc_1013 9.21e-116 334.0 2DM4H@1|root,31PH4@2|Bacteria 2|Bacteria S Protein of unknown function (DUF2589) - - - - - - - - - - - - DUF2589 JFBFHGED_01184 349741.Amuc_1014 3.1e-34 118.0 2EKK3@1|root,33E9Z@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_01186 349741.Amuc_1016 1.4e-73 220.0 COG3530@1|root,COG3530@2|Bacteria,46WAN@74201|Verrucomicrobia,2IUTR@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Putative quorum-sensing-regulated virulence factor - - - ko:K09954 - - - - ko00000 - - - QSregVF_b JFBFHGED_01187 349741.Amuc_1017 3.62e-154 434.0 COG2267@1|root,COG2267@2|Bacteria,46WQX@74201|Verrucomicrobia,2IUN2@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Alpha/beta hydrolase family - - 4.2.99.20 ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08166 RC02148,RC02475 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_6 JFBFHGED_01188 349741.Amuc_1018 2.11e-123 353.0 COG2095@1|root,COG2095@2|Bacteria,46T9S@74201|Verrucomicrobia,2IUN7@203494|Verrucomicrobiae 203494|Verrucomicrobiae U MarC family integral membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC JFBFHGED_01191 349741.Amuc_1022 2.96e-201 560.0 COG2755@1|root,COG2755@2|Bacteria,46VAZ@74201|Verrucomicrobia,2IUIU@203494|Verrucomicrobiae 2|Bacteria E PFAM lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 JFBFHGED_01194 349741.Amuc_1025 1.28e-179 500.0 COG1281@1|root,COG1281@2|Bacteria,46UDA@74201|Verrucomicrobia,2IU4G@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Hsp33 protein - - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 JFBFHGED_01195 349741.Amuc_1026 4.56e-115 330.0 COG0652@1|root,COG0652@2|Bacteria,46V73@74201|Verrucomicrobia,2IU91@203494|Verrucomicrobiae 203494|Verrucomicrobiae O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase JFBFHGED_01196 349741.Amuc_1027 0.0 1205.0 COG0488@1|root,COG0488@2|Bacteria,46V06@74201|Verrucomicrobia,2IU2D@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn JFBFHGED_01197 349741.Amuc_1028 1.38e-111 325.0 2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01198 349741.Amuc_1029 4.41e-194 541.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination ybfH - - - - - - - - - - - EamA JFBFHGED_01199 349741.Amuc_1030 1.93e-54 172.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 JFBFHGED_01200 349741.Amuc_1031 0.0 939.0 COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia,2ITI3@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class I (C) catalytic domain cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1e JFBFHGED_01201 349741.Amuc_1032 0.0 1079.0 COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae 2|Bacteria G Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_01202 349741.Amuc_1033 0.0 1231.0 COG3119@1|root,COG3119@2|Bacteria,46U1Z@74201|Verrucomicrobia,2ITR9@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Domain of unknown function (DUF4976) - - - - - - - - - - - - DUF4976,Sulfatase JFBFHGED_01203 349741.Amuc_1034 8.08e-234 643.0 COG0526@1|root,COG0526@2|Bacteria,46X62@74201|Verrucomicrobia,2IUKR@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Thioredoxin-like - - - - - - - - - - - - Thioredoxin_2,Thioredoxin_7 JFBFHGED_01205 349741.Amuc_1036 0.0 1160.0 COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia,2IU2I@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C JFBFHGED_01206 349741.Amuc_1037 6.21e-39 129.0 29038@1|root,2ZMTB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_01208 349741.Amuc_1039 0.0 2641.0 COG4625@1|root,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter,PATR JFBFHGED_01209 349741.Amuc_1040 0.0 2753.0 COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,2ITYC@203494|Verrucomicrobiae 203494|Verrucomicrobiae K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC - 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 JFBFHGED_01210 349741.Amuc_1041 0.0 2563.0 COG0085@1|root,COG0085@2|Bacteria,46S8Q@74201|Verrucomicrobia,2ITJQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 JFBFHGED_01211 349741.Amuc_1042 2.79e-61 190.0 COG0222@1|root,COG0222@2|Bacteria,46SWC@74201|Verrucomicrobia,2IUI8@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N JFBFHGED_01212 349741.Amuc_1043 1.65e-108 313.0 COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 JFBFHGED_01213 349741.Amuc_1044 6.77e-154 433.0 COG0081@1|root,COG0081@2|Bacteria,46S7K@74201|Verrucomicrobia,2ITZ7@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA - - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 JFBFHGED_01214 349741.Amuc_1045 7.4e-93 271.0 COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,2IUAM@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N JFBFHGED_01215 349741.Amuc_1046 6.29e-135 382.0 COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,2IU6S@203494|Verrucomicrobiae 203494|Verrucomicrobiae K In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. nusG - - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG JFBFHGED_01216 349741.Amuc_1047 3.61e-46 148.0 COG0690@1|root,COG0690@2|Bacteria,46T9W@74201|Verrucomicrobia,2IUWV@203494|Verrucomicrobiae 203494|Verrucomicrobiae U SecE/Sec61-gamma subunits of protein translocation complex - - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE JFBFHGED_01218 349741.Amuc_1048 5.75e-286 781.0 COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,2ITQE@203494|Verrucomicrobiae 203494|Verrucomicrobiae J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 JFBFHGED_01220 349741.Amuc_1049 4.34e-241 664.0 COG0533@1|root,COG0533@2|Bacteria,46SEH@74201|Verrucomicrobia,2ITUT@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 JFBFHGED_01221 349741.Amuc_1050 6.62e-312 852.0 COG1219@1|root,COG1219@2|Bacteria,46SIK@74201|Verrucomicrobia,2ITIB@203494|Verrucomicrobiae 203494|Verrucomicrobiae O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX - - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX JFBFHGED_01222 349741.Amuc_1051 2.42e-139 395.0 COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,2ITX1@203494|Verrucomicrobiae 203494|Verrucomicrobiae OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease JFBFHGED_01223 349741.Amuc_1052 6.99e-274 754.0 COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,2ITGE@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N JFBFHGED_01224 349741.Amuc_1053 0.0 1587.0 COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,2ITS5@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Surface antigen - - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA JFBFHGED_01225 349741.Amuc_1054 6.85e-130 374.0 COG2850@1|root,COG2850@2|Bacteria 2|Bacteria P peptidyl-arginine hydroxylation - - 1.14.11.27 ko:K10277 - - - - ko00000,ko01000,ko03036 - - - Cupin_8 JFBFHGED_01226 349741.Amuc_1055 1.27e-222 613.0 COG0685@1|root,COG0685@2|Bacteria,46UW6@74201|Verrucomicrobia,2ITT5@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR JFBFHGED_01227 349741.Amuc_1056 6.28e-165 462.0 COG2976@1|root,COG2976@2|Bacteria 2|Bacteria CO Protein conserved in bacteria - - - - - - - - - - - - TPR_16,TPR_19,TPR_21,TPR_6,TPR_8 JFBFHGED_01229 349741.Amuc_1058 7.47e-141 398.0 COG1309@1|root,COG1309@2|Bacteria,46XR9@74201|Verrucomicrobia,2IWEP@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N JFBFHGED_01230 349741.Amuc_1059 0.0 1903.0 COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,2ITM5@203494|Verrucomicrobiae 203494|Verrucomicrobiae P AcrB/AcrD/AcrF family - - - ko:K07239 - - - - ko00000 2.A.6.1 - - ACR_tran JFBFHGED_01231 349741.Amuc_1060 9.88e-265 734.0 COG0845@1|root,COG0845@2|Bacteria 2|Bacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family czcB - - ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - HlyD_D23 JFBFHGED_01232 349741.Amuc_1061 3.42e-279 766.0 COG1538@1|root,COG1538@2|Bacteria 2|Bacteria MU efflux transmembrane transporter activity - - - ko:K15725 - - - - ko00000,ko02000 1.B.17.2.2 - - OEP JFBFHGED_01234 349741.Amuc_1063 1.62e-185 522.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus - - - ko:K06867,ko:K07001 - - - - ko00000 - - - Ank,Ank_2,Ank_4,Ank_5,Fic,Sel1 JFBFHGED_01235 349741.Amuc_1064 0.0 917.0 COG3104@1|root,COG3104@2|Bacteria,46VMC@74201|Verrucomicrobia 74201|Verrucomicrobia E PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 JFBFHGED_01239 349741.Amuc_1067 3.15e-204 566.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia,2ITX6@203494|Verrucomicrobiae 203494|Verrucomicrobiae KQ Hypothetical methyltransferase - - - - - - - - - - - - HTH_5,Methyltransf_11,Methyltransf_31 JFBFHGED_01240 349741.Amuc_1068 2.93e-279 764.0 COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia,2ITRU@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N JFBFHGED_01241 349741.Amuc_1069 0.0 921.0 COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,2ITJN@203494|Verrucomicrobiae 203494|Verrucomicrobiae H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD JFBFHGED_01243 349741.Amuc_1071 4.76e-229 632.0 2E0IP@1|root,32W4A@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_01244 349741.Amuc_1072 1.15e-280 769.0 COG1232@1|root,COG1232@2|Bacteria,46Z36@74201|Verrucomicrobia,2IUYM@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase JFBFHGED_01245 349741.Amuc_1073 1.13e-158 451.0 2A4B8@1|root,30SWV@2|Bacteria 349741.Amuc_1073|- - - - - - - - - - - - - - - - JFBFHGED_01246 349741.Amuc_1074 0.0 1130.0 COG3119@1|root,COG3119@2|Bacteria,46U1Z@74201|Verrucomicrobia,2ITR9@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Domain of unknown function (DUF4976) - - - - - - - - - - - - DUF4976,Sulfatase JFBFHGED_01247 349741.Amuc_1075 0.0 1111.0 COG0514@1|root,COG0514@2|Bacteria,46UKY@74201|Verrucomicrobia,2ITR5@203494|Verrucomicrobiae 203494|Verrucomicrobiae L RecQ zinc-binding - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind JFBFHGED_01249 349741.Amuc_1077 3.18e-224 624.0 COG0438@1|root,COG0438@2|Bacteria,46ZHN@74201|Verrucomicrobia,2IUVI@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JFBFHGED_01250 349741.Amuc_1078 2.18e-225 623.0 COG3868@1|root,COG3868@2|Bacteria,46STS@74201|Verrucomicrobia,2IU5G@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Glycoside-hydrolase family GH114 - - - - - - - - - - - - - JFBFHGED_01251 349741.Amuc_1079 0.0 1066.0 COG0029@1|root,COG0029@2|Bacteria,46SHQ@74201|Verrucomicrobia,2ITSA@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Fumarate reductase flavoprotein C-term - - 1.4.3.16 ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481 RC00006,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C JFBFHGED_01252 349741.Amuc_1080 1.72e-130 371.0 COG0566@1|root,COG0566@2|Bacteria,46VH3@74201|Verrucomicrobia,2IUB5@203494|Verrucomicrobiae 203494|Verrucomicrobiae J SpoU rRNA Methylase family - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase JFBFHGED_01253 349741.Amuc_1081 5.58e-182 508.0 COG0420@1|root,COG0420@2|Bacteria 2|Bacteria L 3'-5' exonuclease activity - - 3.1.1.53 ko:K03547,ko:K05970 - - - - ko00000,ko01000,ko03400 - - - Metallophos,Metallophos_2 JFBFHGED_01254 349741.Amuc_1082 5.72e-80 238.0 COG1321@1|root,COG1321@2|Bacteria,46VZN@74201|Verrucomicrobia,2IUJN@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Helix-turn-helix diphteria tox regulatory element - - - - - - - - - - - - Fe_dep_repr_C,Fe_dep_repress JFBFHGED_01255 349741.Amuc_1083 0.0 1233.0 COG2217@1|root,COG2217@2|Bacteria,46UK0@74201|Verrucomicrobia,2ITIY@203494|Verrucomicrobiae 203494|Verrucomicrobiae P E1-E2 ATPase - - - - - - - - - - - - ATPase-cat_bd,E1-E2_ATPase,Hydrolase JFBFHGED_01262 349741.Amuc_1088 0.0 1308.0 COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,2ITUZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Ferrous iron transport protein B C terminus - - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate JFBFHGED_01263 349741.Amuc_1089 4.02e-48 153.0 COG1918@1|root,COG1918@2|Bacteria 2|Bacteria P iron ion homeostasis feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA JFBFHGED_01264 349741.Amuc_1090 2.67e-39 130.0 COG1918@1|root,COG1918@2|Bacteria 2|Bacteria P iron ion homeostasis feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA JFBFHGED_01265 349741.Amuc_1091 0.0 895.0 COG1858@1|root,COG1858@2|Bacteria,46U0N@74201|Verrucomicrobia,2IUGP@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Di-haem cytochrome c peroxidase - - 1.11.1.5 ko:K00428 - - - - ko00000,ko01000 - - - CCP_MauG,Cytochrom_C JFBFHGED_01266 349741.Amuc_1092 9.28e-221 609.0 COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,2ITX7@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA - 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM JFBFHGED_01267 349741.Amuc_1093 3.16e-123 352.0 COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia,2IUAZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam JFBFHGED_01268 349741.Amuc_1094 1.7e-217 602.0 COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia,2ITKM@203494|Verrucomicrobiae 203494|Verrucomicrobiae GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK JFBFHGED_01269 349741.Amuc_1095 0.0 1060.0 COG2217@1|root,COG2217@2|Bacteria,46TN5@74201|Verrucomicrobia,2IWNK@203494|Verrucomicrobiae 203494|Verrucomicrobiae P E1-E2 ATPase - - - - - - - - - - - - E1-E2_ATPase,Hydrolase JFBFHGED_01271 349741.Amuc_1096 3.62e-304 834.0 COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,2ITR1@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_RNA_bind JFBFHGED_01272 349741.Amuc_1097 3e-123 353.0 COG0237@1|root,COG0237@2|Bacteria,46X3P@74201|Verrucomicrobia,2IUJH@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE - 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE JFBFHGED_01273 349741.Amuc_1098 0.0 1636.0 COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Bacterial type II and III secretion system protein - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin JFBFHGED_01274 349741.Amuc_1099 1.02e-232 641.0 2AW6M@1|root,31N1N@2|Bacteria,46X8K@74201|Verrucomicrobia,2IV0K@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01275 349741.Amuc_1100 4e-195 545.0 28V7G@1|root,2ZHAM@2|Bacteria,46WJH@74201|Verrucomicrobia,2IUZ5@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01276 349741.Amuc_1101 0.0 1097.0 COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia,2ITTF@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Type IV pilus assembly protein PilM; - - - - - - - - - - - - PilM_2 JFBFHGED_01277 349741.Amuc_1102 9.54e-154 433.0 28VCA@1|root,2ZHF0@2|Bacteria,46WID@74201|Verrucomicrobia,2IUQZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01278 349741.Amuc_1103 8.47e-243 669.0 COG1363@1|root,COG1363@2|Bacteria,46YYD@74201|Verrucomicrobia,2ITUN@203494|Verrucomicrobiae 203494|Verrucomicrobiae G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 JFBFHGED_01279 349741.Amuc_1104 2.66e-247 679.0 COG0682@1|root,COG0682@2|Bacteria,46SSY@74201|Verrucomicrobia,2IU4I@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT JFBFHGED_01280 349741.Amuc_1105 4.73e-36 127.0 2DSS0@1|root,33H81@2|Bacteria,46XPW@74201|Verrucomicrobia,2IWCC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 JFBFHGED_01281 349741.Amuc_1105 1.19e-75 231.0 2DSS0@1|root,33H81@2|Bacteria,46XPW@74201|Verrucomicrobia,2IWCC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF3313) - - - - - - - - - - - - DUF3313 JFBFHGED_01283 349741.Amuc_1106 2.25e-302 825.0 COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia,2ITPD@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminopeptidase P, N-terminal domain - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 JFBFHGED_01284 349741.Amuc_1107 1.58e-206 571.0 COG0040@1|root,COG0040@2|Bacteria,46SHK@74201|Verrucomicrobia,2ITH9@203494|Verrucomicrobiae 203494|Verrucomicrobiae E ATP phosphoribosyltransferase hisG - 2.4.2.17 ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C JFBFHGED_01285 349741.Amuc_1108 2.09e-10 55.5 2A2WF@1|root,30RAJ@2|Bacteria,46Y7F@74201|Verrucomicrobia,2IUX3@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Mitochondrial domain of unknown function (DUF1713) - - - - - - - - - - - - DUF1713 JFBFHGED_01289 349741.Amuc_1109 1.56e-277 761.0 COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,2ITKV@203494|Verrucomicrobiae 203494|Verrucomicrobiae T His Kinase A (phosphoacceptor) domain - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA JFBFHGED_01290 349741.Amuc_1110 3.14e-164 459.0 COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,2IU6U@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Transcriptional regulatory protein, C terminal - - - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C JFBFHGED_01291 349741.Amuc_1111 0.0 1071.0 COG0129@1|root,COG0129@2|Bacteria,46SBY@74201|Verrucomicrobia,2ITPZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae EG Dehydratase family - - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD JFBFHGED_01293 349741.Amuc_1114 0.0 2078.0 COG4625@1|root,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter JFBFHGED_01294 349741.Amuc_1115 8.62e-224 621.0 COG4974@1|root,COG4974@2|Bacteria,46Z6H@74201|Verrucomicrobia,2IWPR@203494|Verrucomicrobiae 2|Bacteria L Belongs to the 'phage' integrase family xerD1 - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase JFBFHGED_01295 349741.Amuc_1116 3.1e-182 511.0 COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia,2IU8Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Uracil DNA glycosylase superfamily - - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG JFBFHGED_01296 349741.Amuc_1117 8.98e-275 751.0 COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia,2ITUU@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Biotin and Thiamin Synthesis associated domain - - 4.1.99.19 ko:K03150 ko00730,ko01100,map00730,map01100 - R10246 RC01434,RC03095 ko00000,ko00001,ko01000 - - - BATS,Radical_SAM JFBFHGED_01297 349741.Amuc_1118 0.0 1204.0 COG1368@1|root,COG1368@2|Bacteria,46U99@74201|Verrucomicrobia,2IVIY@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Sulfatase - - - - - - - - - - - - Sulfatase JFBFHGED_01298 349741.Amuc_1119 5.19e-273 747.0 2EMB5@1|root,33F05@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_01299 349741.Amuc_1120 0.0 1540.0 COG1554@1|root,COG1554@2|Bacteria,46TM2@74201|Verrucomicrobia,2IV0H@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 65, N-terminal domain - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Glyco_hyd_65N_2 JFBFHGED_01300 349741.Amuc_1121 2.69e-284 782.0 28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia,2ITXI@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF2851) - - - - - - - - - - - - DUF2851 JFBFHGED_01301 349741.Amuc_1122 1.45e-115 332.0 COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,2IURI@203494|Verrucomicrobiae 203494|Verrucomicrobiae T STAS domain - - - - - - - - - - - - STAS JFBFHGED_01302 349741.Amuc_1124 9.92e-247 691.0 COG1657@1|root,COG1657@2|Bacteria,46V9U@74201|Verrucomicrobia,2ITZJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Prenyltransferase and squalene oxidase repeat - - - - - - - - - - - - Prenyltrans JFBFHGED_01303 349741.Amuc_1123 1.28e-313 860.0 COG1657@1|root,COG1657@2|Bacteria,46V9U@74201|Verrucomicrobia,2ITZJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Prenyltransferase and squalene oxidase repeat - - - - - - - - - - - - Prenyltrans JFBFHGED_01304 349741.Amuc_1124 6.62e-313 860.0 COG1657@1|root,COG1657@2|Bacteria,46V9U@74201|Verrucomicrobia,2ITZJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Prenyltransferase and squalene oxidase repeat - - - - - - - - - - - - Prenyltrans JFBFHGED_01305 349741.Amuc_1125 1.54e-239 660.0 COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia,2ITS1@203494|Verrucomicrobiae 203494|Verrucomicrobiae M NmrA-like family - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd JFBFHGED_01306 349741.Amuc_1126 0.0 872.0 COG0030@1|root,COG1443@1|root,COG0030@2|Bacteria,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,2ITVV@203494|Verrucomicrobiae 203494|Verrucomicrobiae IJ Ribosomal RNA adenine dimethylases - - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - NUDIX,RrnaAD JFBFHGED_01307 349741.Amuc_1127 2.39e-92 271.0 2FBS3@1|root,343WW@2|Bacteria,46X6J@74201|Verrucomicrobia,2IUQ7@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01308 226186.BT_2340 1.61e-40 135.0 2BH08@1|root,32B0C@2|Bacteria,4P6E5@976|Bacteroidetes,2FXT5@200643|Bacteroidia,4AU22@815|Bacteroidaceae 976|Bacteroidetes S TfoX C-terminal domain - - - ko:K07343 - - - - ko00000 - - - TfoX_C JFBFHGED_01309 349741.Amuc_1128 5.3e-49 156.0 2AX33@1|root,31P1F@2|Bacteria,46XQB@74201|Verrucomicrobia,2IWD6@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01310 349741.Amuc_1129 2.04e-90 276.0 2AW63@1|root,31N13@2|Bacteria,46X8D@74201|Verrucomicrobia,2IUZY@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01311 349741.Amuc_1131 4.25e-291 798.0 COG0534@1|root,COG0534@2|Bacteria 2|Bacteria V drug transmembrane transporter activity - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE JFBFHGED_01312 349741.Amuc_1132 0.0 1115.0 COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia,2IVH0@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Cation transport protein - - - - - - - - - - - - TrkH JFBFHGED_01314 1122225.AULQ01000012_gene453 4.5e-97 298.0 COG3386@1|root,COG3386@2|Bacteria,4NFRT@976|Bacteroidetes,1IJNN@117743|Flavobacteriia 976|Bacteroidetes G Major royal jelly protein - - - - - - - - - - - - MRJP JFBFHGED_01315 349741.Amuc_1162 8.9e-247 677.0 COG2008@1|root,COG2008@2|Bacteria,46SB9@74201|Verrucomicrobia,2IW5S@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Beta-eliminating lyase - - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase JFBFHGED_01316 349741.Amuc_1171 1.39e-261 719.0 COG2311@1|root,COG2311@2|Bacteria,46VK7@74201|Verrucomicrobia,2IUSC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF1624,DUF418 JFBFHGED_01317 709991.Odosp_0465 4.57e-65 203.0 COG1881@1|root,COG1881@2|Bacteria,4NH14@976|Bacteroidetes 976|Bacteroidetes S TIGRFAM Raf kinase inhibitor-like protein, YbhB YbcL family - - - ko:K06910 - - - - ko00000 - - - PBP JFBFHGED_01318 349741.Amuc_1173 3.05e-203 566.0 COG0399@1|root,COG0399@2|Bacteria 2|Bacteria E UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - - - - - - - - - - Aminotran_5,Cys_Met_Meta_PP,DegT_DnrJ_EryC1 JFBFHGED_01320 349741.Amuc_1175 1.84e-191 538.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion - - - - - - - - - - - - Band_7 JFBFHGED_01321 349741.Amuc_1176 4.89e-184 514.0 COG1090@1|root,COG1090@2|Bacteria,46V7D@74201|Verrucomicrobia,2IUFW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF1731) - - - ko:K07071 - - - - ko00000 - - - DUF1731,Epimerase JFBFHGED_01322 349741.Amuc_1177 3.33e-106 308.0 COG3040@1|root,COG3040@2|Bacteria,46WHH@74201|Verrucomicrobia,2IUQU@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Lipocalin-like domain - - - ko:K03098 - - - - ko00000,ko04147 - - - Lipocalin_2 JFBFHGED_01323 349741.Amuc_1178 2.14e-233 642.0 COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,2ITY3@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate - - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN JFBFHGED_01324 349741.Amuc_1179 2.69e-185 515.0 COG1119@1|root,COG1119@2|Bacteria,46SN3@74201|Verrucomicrobia,2IVY6@203494|Verrucomicrobiae 203494|Verrucomicrobiae P ATPases associated with a variety of cellular activities - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran JFBFHGED_01325 349741.Amuc_1180 7.78e-143 405.0 COG2186@1|root,COG2186@2|Bacteria 2|Bacteria K Transcriptional regulator - - - - - - - - - - - - FCD,GntR JFBFHGED_01329 349741.Amuc_1182 0.0 886.0 COG3119@1|root,COG3119@2|Bacteria,46TNU@74201|Verrucomicrobia,2IUAA@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Sulfatase - - - - - - - - - - - - Sulfatase JFBFHGED_01330 349741.Amuc_1183 1.04e-78 234.0 COG2919@1|root,COG2919@2|Bacteria 2|Bacteria D cell cycle divIC - - ko:K05589,ko:K13052 - - - - ko00000,ko03036 - - - DivIC JFBFHGED_01331 349741.Amuc_1184 3.47e-300 820.0 COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,2ITUV@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N JFBFHGED_01333 1121324.CLIT_8c00190 7.35e-81 254.0 COG0350@1|root,COG4912@1|root,COG0350@2|Bacteria,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,25RFD@186804|Peptostreptococcaceae 186801|Clostridia L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation JFBFHGED_01334 349741.Amuc_1185 1.35e-302 829.0 COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia,2ITKU@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 JFBFHGED_01335 566461.SSFG_06674 1.01e-09 72.0 COG2133@1|root,COG2133@2|Bacteria,2GRVP@201174|Actinobacteria 201174|Actinobacteria G PA14 - - - - - - - - - - - - CBM_35,DUF1080,PA14 JFBFHGED_01336 349741.Amuc_1186 1.59e-151 436.0 COG1477@1|root,COG1477@2|Bacteria,46V70@74201|Verrucomicrobia,2IUN9@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE JFBFHGED_01337 349741.Amuc_1187 0.0 974.0 COG1501@1|root,COG1501@2|Bacteria,46UJE@74201|Verrucomicrobia,2IUGJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha galactosidase A - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - He_PIG_assoc,Melibiase_2 JFBFHGED_01338 349741.Amuc_1188 1.04e-49 157.0 2EIJD@1|root,33CAP@2|Bacteria,46WH7@74201|Verrucomicrobia,2IW3W@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01339 349741.Amuc_1189 1.45e-55 173.0 COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,2IUUU@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal L28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 JFBFHGED_01340 349741.Amuc_1190 7.04e-214 593.0 COG0604@1|root,COG0604@2|Bacteria,46UF3@74201|Verrucomicrobia,2ITYR@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N JFBFHGED_01342 349741.Amuc_1191 9.38e-91 266.0 COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,2IUHN@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Likely ribonuclease with RNase H fold. - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX JFBFHGED_01343 349741.Amuc_1192 4.11e-251 689.0 COG0836@1|root,COG0836@2|Bacteria,46SAQ@74201|Verrucomicrobia,2ITXZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Nucleotidyl transferase - - 2.7.7.13 ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase JFBFHGED_01344 349741.Amuc_1193 3.46e-154 434.0 COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids - - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf JFBFHGED_01345 349741.Amuc_1194 0.0 1195.0 COG0187@1|root,COG0187@2|Bacteria,46UY6@74201|Verrucomicrobia,2ITJR@203494|Verrucomicrobiae 203494|Verrucomicrobiae L TopoisomeraseII - - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim JFBFHGED_01346 349741.Amuc_1195 2.56e-187 522.0 COG1947@1|root,COG1947@2|Bacteria,46SV6@74201|Verrucomicrobia,2IU5F@203494|Verrucomicrobiae 203494|Verrucomicrobiae I GHMP kinases N terminal domain ispE - 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N JFBFHGED_01348 349741.Amuc_1197 0.0 1242.0 COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia,2ITJT@203494|Verrucomicrobiae 203494|Verrucomicrobiae L HELICc2 - - 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2 JFBFHGED_01349 349741.Amuc_1198 1.2e-163 460.0 COG1122@1|root,COG1122@2|Bacteria 2|Bacteria P ATPase activity cbiO - - ko:K02006,ko:K02008,ko:K16784,ko:K16786 ko02010,map02010 M00245,M00246,M00581,M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran JFBFHGED_01350 349741.Amuc_1199 6.45e-175 489.0 COG0619@1|root,COG0619@2|Bacteria 2|Bacteria P transmembrane transporter activity cbiQ GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02007,ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ JFBFHGED_01351 349741.Amuc_1200 1.21e-211 589.0 COG0310@1|root,COG0310@2|Bacteria 2|Bacteria P cobalt ion transport cbiM - - ko:K02007,ko:K02009,ko:K16915 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - iAF987.Gmet_2441 CbiM,PDGLE JFBFHGED_01354 349741.Amuc_1203 1.64e-205 569.0 COG0548@1|root,COG0548@2|Bacteria,46SH9@74201|Verrucomicrobia,2ITVB@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Amino acid kinase family argB - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase JFBFHGED_01355 349741.Amuc_1204 3.5e-225 622.0 COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,2IU92@203494|Verrucomicrobiae 203494|Verrucomicrobiae P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA JFBFHGED_01356 349741.Amuc_1205 7.19e-93 272.0 COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,2IUF8@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L9, N-terminal domain rplI - - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N JFBFHGED_01357 349741.Amuc_1206 0.0 1015.0 COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,2ITYZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae F AICARFT/IMPCHase bienzyme - - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS JFBFHGED_01358 349741.Amuc_1207 8.61e-168 469.0 COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia,2ITP1@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ - 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ JFBFHGED_01359 349741.Amuc_1208 3.85e-76 228.0 COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia,2IUTE@203494|Verrucomicrobiae 203494|Verrucomicrobiae I 4'-phosphopantetheinyl transferase superfamily acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS JFBFHGED_01362 883126.HMPREF9710_01314 9.42e-07 59.3 COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,2WCWE@28216|Betaproteobacteria,478B5@75682|Oxalobacteraceae 28216|Betaproteobacteria H lysine biosynthetic process via aminoadipic acid - - - - - - - - - - - - - JFBFHGED_01363 349741.Amuc_1210 0.0 1273.0 COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia,2ITQG@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle pckG - 4.1.1.32 ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 M00003 R00431,R00726 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_C,PEPCK_N JFBFHGED_01364 349741.Amuc_1211 4.85e-158 443.0 COG5632@1|root,COG5632@2|Bacteria,46VKP@74201|Verrucomicrobia,2IU5K@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM N-acetylmuramoyl-L-alanine amidase family 2 - - 3.5.1.28 ko:K01447 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Amidase_2 JFBFHGED_01365 349741.Amuc_1212 0.0 1273.0 COG1200@1|root,COG1200@2|Bacteria,46TTC@74201|Verrucomicrobia,2ITXG@203494|Verrucomicrobiae 203494|Verrucomicrobiae L RecG wedge domain - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge JFBFHGED_01367 349741.Amuc_1214 0.0 1682.0 COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,2ITQX@203494|Verrucomicrobiae 203494|Verrucomicrobiae C 4Fe-4S dicluster domain - - - ko:K00184 - - - - ko00000 5.A.3 - - Fer4_7 JFBFHGED_01369 349741.Amuc_1215 2.92e-169 472.0 COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,2IU6R@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Cytochrome c7 and related cytochrome c - - - - - - - - - - - - Cytochrome_C7 JFBFHGED_01370 349741.Amuc_1216 2.36e-283 776.0 COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA JFBFHGED_01372 349741.Amuc_1218 4.19e-244 673.0 COG0337@1|root,COG0337@2|Bacteria,46SRE@74201|Verrucomicrobia,2ITYW@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Iron-containing alcohol dehydrogenase aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase JFBFHGED_01376 349741.Amuc_1220 1.95e-212 610.0 COG3525@1|root,COG3669@1|root,COG3525@2|Bacteria,COG3669@2|Bacteria,46X9G@74201|Verrucomicrobia,2IV3U@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain - - - - - - - - - - - - NAGLU,NAGLU_C,NAGLU_N JFBFHGED_01377 349741.Amuc_1220 1.55e-311 868.0 COG3525@1|root,COG3669@1|root,COG3525@2|Bacteria,COG3669@2|Bacteria,46X9G@74201|Verrucomicrobia,2IV3U@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain - - - - - - - - - - - - NAGLU,NAGLU_C,NAGLU_N JFBFHGED_01378 349741.Amuc_1222 0.0 1138.0 COG1297@1|root,COG1297@2|Bacteria,46TNW@74201|Verrucomicrobia,2IV9P@203494|Verrucomicrobiae 203494|Verrucomicrobiae S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT JFBFHGED_01379 349741.Amuc_1223 5.08e-169 474.0 COG0284@1|root,COG0284@2|Bacteria,46YTH@74201|Verrucomicrobia,2IU2E@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Orotidine 5'-phosphate decarboxylase / HUMPS family - - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase JFBFHGED_01381 349741.Amuc_1225 0.0 1048.0 COG1227@1|root,COG3448@1|root,COG4109@1|root,COG1227@2|Bacteria,COG3448@2|Bacteria,COG4109@2|Bacteria,46UKX@74201|Verrucomicrobia,2ITG8@203494|Verrucomicrobiae 203494|Verrucomicrobiae C DHHA2 - - 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - CBS,DHH,DHHA2,DRTGG JFBFHGED_01382 349741.Amuc_1226 3.93e-206 573.0 COG3568@1|root,COG3568@2|Bacteria 2|Bacteria N Endonuclease Exonuclease Phosphatase - - - ko:K18353 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01504 - - - Exo_endo_phos JFBFHGED_01383 349741.Amuc_1227 7.63e-59 182.0 COG0718@1|root,COG0718@2|Bacteria,46TA9@74201|Verrucomicrobia,2IUTH@203494|Verrucomicrobiae 203494|Verrucomicrobiae L YbaB/EbfC DNA-binding family - - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd JFBFHGED_01384 349741.Amuc_1228 0.0 955.0 COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,2ITGI@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 JFBFHGED_01386 349741.Amuc_1230 1.81e-154 438.0 COG5185@1|root,COG5185@2|Bacteria,46WAF@74201|Verrucomicrobia,2IUTM@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Phage-related minor tail protein - - - - - - - - - - - - - JFBFHGED_01389 349741.Amuc_1231 2.33e-156 441.0 COG2003@1|root,COG2003@2|Bacteria,46STQ@74201|Verrucomicrobia,2IU7T@203494|Verrucomicrobiae 203494|Verrucomicrobiae L RadC-like JAB domain - - - ko:K03630 - - - - ko00000 - - - RadC JFBFHGED_01390 349741.Amuc_1232 0.0 917.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,46S7Z@74201|Verrucomicrobia,2ITJV@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N JFBFHGED_01391 349741.Amuc_1233 6.12e-40 132.0 COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia,2IUS9@203494|Verrucomicrobiae 203494|Verrucomicrobiae J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a JFBFHGED_01392 349741.Amuc_1234 5.64e-97 282.0 COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 JFBFHGED_01393 349741.Amuc_1235 1.38e-85 252.0 COG0103@1|root,COG0103@2|Bacteria,46SXI@74201|Verrucomicrobia,2IUDJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S9/S16 rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 JFBFHGED_01395 349741.Amuc_1236 6.26e-91 267.0 COG1576@1|root,COG1576@2|Bacteria,46VXG@74201|Verrucomicrobia,2IUIQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Predicted SPOUT methyltransferase - - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase JFBFHGED_01396 349741.Amuc_1237 0.0 935.0 COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,2IU0I@203494|Verrucomicrobiae 203494|Verrucomicrobiae L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision - - - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,UVR,UvrC_HhH_N JFBFHGED_01397 349741.Amuc_1238 8.27e-179 499.0 COG0811@1|root,COG0811@2|Bacteria,46SY0@74201|Verrucomicrobia,2IU5B@203494|Verrucomicrobiae 203494|Verrucomicrobiae U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB JFBFHGED_01398 349741.Amuc_1239 3.46e-94 275.0 COG0848@1|root,COG0848@2|Bacteria,46T1K@74201|Verrucomicrobia,2IUJ8@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD JFBFHGED_01399 349741.Amuc_1240 0.0 1463.0 COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46UJD@74201|Verrucomicrobia,2IU8M@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_6,TPR_8 JFBFHGED_01400 349741.Amuc_1241 0.0 1081.0 COG0744@1|root,COG0744@2|Bacteria,46U6K@74201|Verrucomicrobia 74201|Verrucomicrobia M PFAM glycosyl transferase family 51 - - - - - - - - - - - - Transgly JFBFHGED_01401 349741.Amuc_1242 1.48e-175 489.0 COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia,2IU5U@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P JFBFHGED_01402 349741.Amuc_1243 8.12e-110 317.0 COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia,2IUAJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 4.6.1.12 ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - YgbB JFBFHGED_01404 349741.Amuc_1254 0.0 1113.0 COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,2ITX0@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas JFBFHGED_01405 349741.Amuc_1255 5.88e-55 171.0 COG0759@1|root,COG0759@2|Bacteria,46W3D@74201|Verrucomicrobia,2IW7G@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Haemolytic - - - ko:K08998 - - - - ko00000 - - - Haemolytic JFBFHGED_01406 349741.Amuc_1256 6.7e-74 221.0 COG0594@1|root,COG0594@2|Bacteria,46WEU@74201|Verrucomicrobia,2IUWY@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribonuclease P - - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P JFBFHGED_01407 349741.Amuc_1257 1.1e-34 118.0 COG0230@1|root,COG0230@2|Bacteria,46WMF@74201|Verrucomicrobia,2IUR8@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L34 - - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 JFBFHGED_01408 349741.Amuc_1258 0.0 1321.0 COG3968@1|root,COG3968@2|Bacteria 2|Bacteria S glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - GSIII_N,Gln-synt_C JFBFHGED_01409 349741.Amuc_1261 1.55e-176 494.0 COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia,2IUNW@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Aldose 1-epimerase - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim JFBFHGED_01410 349741.Amuc_1262 1.3e-152 428.0 COG0259@1|root,COG0259@2|Bacteria,46SRQ@74201|Verrucomicrobia,2IU4K@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) - - 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx JFBFHGED_01411 349741.Amuc_1263 1.12e-188 526.0 COG0157@1|root,COG0157@2|Bacteria,46SPY@74201|Verrucomicrobia,2IU3B@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Quinolinate phosphoribosyl transferase, N-terminal domain - - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N JFBFHGED_01412 349741.Amuc_1264 1.62e-200 556.0 COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,2IU28@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Polyprenyl synthetase - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt JFBFHGED_01413 349741.Amuc_1265 1.15e-233 644.0 COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia,2ITM6@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC JFBFHGED_01414 349741.Amuc_1267 6.39e-166 463.0 2A8AI@1|root,30XBY@2|Bacteria,46SPH@74201|Verrucomicrobia,2IU9U@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01415 349741.Amuc_1268 0.0 875.0 COG1760@1|root,COG1760@2|Bacteria,46T1Q@74201|Verrucomicrobia,2ITXM@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Serine dehydratase alpha chain - - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta JFBFHGED_01416 349741.Amuc_1269 1.94e-216 598.0 COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Pyridine nucleotide-disulphide oxidoreductase - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 JFBFHGED_01417 349741.Amuc_1270 5.02e-162 459.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - ko:K00612 - - - - ko00000,ko01000 - - - Lipase_GDSL_2 JFBFHGED_01420 349741.Amuc_1271 3.25e-125 357.0 COG0454@1|root,COG0454@2|Bacteria 2|Bacteria K -acetyltransferase panZ - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3616,DUF3749 JFBFHGED_01423 349741.Amuc_1277 4.21e-125 360.0 COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia,2IUHD@203494|Verrucomicrobiae 203494|Verrucomicrobiae L TatD related DNase - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase JFBFHGED_01424 349741.Amuc_1278 0.0 1036.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,46YYA@74201|Verrucomicrobia,2ITU7@203494|Verrucomicrobiae 203494|Verrucomicrobiae P TrkA-N domain - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N JFBFHGED_01425 349741.Amuc_1279 4.27e-189 526.0 COG1408@1|root,COG1408@2|Bacteria,46W5P@74201|Verrucomicrobia 74201|Verrucomicrobia S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07098 - - - - ko00000 - - - Metallophos JFBFHGED_01426 349741.Amuc_1280 5.62e-253 695.0 COG2309@1|root,COG2309@2|Bacteria,46SAI@74201|Verrucomicrobia,2ITU9@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Thermophilic metalloprotease (M29) - - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 JFBFHGED_01427 349741.Amuc_1281 3.89e-132 375.0 COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia,2IU5Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N JFBFHGED_01428 349741.Amuc_1282 2.03e-186 519.0 COG0545@1|root,COG0545@2|Bacteria,46VYS@74201|Verrucomicrobia,2IUFJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Domain amino terminal to FKBP-type peptidyl-prolyl isomerase - - 5.2.1.8 ko:K03773 - - - - ko00000,ko01000,ko03110 - - - FKBP_C,FKBP_N JFBFHGED_01429 349741.Amuc_1283 0.0 3960.0 COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46VHK@74201|Verrucomicrobia,2IW1Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Passenger-associated-transport-repeat - - - - - - - - - - - - PATR JFBFHGED_01430 349741.Amuc_1285 0.0 1621.0 COG0187@1|root,COG0187@2|Bacteria,46SDH@74201|Verrucomicrobia,2IU0E@203494|Verrucomicrobiae 203494|Verrucomicrobiae L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim JFBFHGED_01431 349741.Amuc_1286 0.0 1535.0 COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia,2ITMM@203494|Verrucomicrobiae 203494|Verrucomicrobiae L DNA Topoisomerase IV - - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV JFBFHGED_01432 349741.Amuc_1287 3.5e-127 364.0 COG1139@1|root,COG1139@2|Bacteria 2|Bacteria C lactate oxidation - - - - - - - - - - - - LUD_dom JFBFHGED_01433 349741.Amuc_1288 2.96e-273 751.0 COG0826@1|root,COG0826@2|Bacteria,46TRX@74201|Verrucomicrobia,2IVH9@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Peptidase family U32 - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 JFBFHGED_01434 349741.Amuc_1290 0.0 2210.0 COG0823@1|root,COG1262@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,46TMC@74201|Verrucomicrobia,2IVG8@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - JFBFHGED_01435 349741.Amuc_1291 0.0 1077.0 COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae 203494|Verrucomicrobiae C cytochrome C peroxidase - - - - - - - - - - - - CCP_MauG JFBFHGED_01436 349741.Amuc_1292 1.39e-242 669.0 COG0251@1|root,COG0251@2|Bacteria,46V48@74201|Verrucomicrobia 74201|Verrucomicrobia J PFAM Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP JFBFHGED_01438 349741.Amuc_1302 2.42e-138 393.0 COG0704@1|root,COG0704@2|Bacteria 2|Bacteria P negative regulation of phosphate transmembrane transport phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU JFBFHGED_01439 349741.Amuc_1303 1.56e-181 505.0 COG1117@1|root,COG1117@2|Bacteria,46SB2@74201|Verrucomicrobia,2ITRC@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran JFBFHGED_01440 349741.Amuc_1304 0.0 1066.0 COG0581@1|root,COG0581@2|Bacteria,46SBK@74201|Verrucomicrobia,2ITN9@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Binding-protein-dependent transport system inner membrane component - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 JFBFHGED_01441 349741.Amuc_1305 0.0 1393.0 COG4590@1|root,COG4590@2|Bacteria 2|Bacteria P Binding-protein-dependent transport system inner membrane component pstC - - ko:K02037,ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 JFBFHGED_01442 349741.Amuc_1306 9.8e-211 584.0 COG0226@1|root,COG0226@2|Bacteria,46SP0@74201|Verrucomicrobia,2IU59@203494|Verrucomicrobiae 203494|Verrucomicrobiae P PBP superfamily domain - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 JFBFHGED_01445 349741.Amuc_0172 0.0 1601.0 2F4ED@1|root,33X4P@2|Bacteria,46VJA@74201|Verrucomicrobia,2IUYK@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01446 349741.Amuc_0172 4.31e-180 539.0 2F4ED@1|root,33X4P@2|Bacteria,46VJA@74201|Verrucomicrobia,2IUYK@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01447 349741.Amuc_1307 3.96e-180 502.0 COG1117@1|root,COG1117@2|Bacteria,46SB2@74201|Verrucomicrobia,2ITRC@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran JFBFHGED_01448 349741.Amuc_1308 7.74e-126 361.0 COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,2IUGT@203494|Verrucomicrobiae 203494|Verrucomicrobiae P PhoU domain - - - ko:K02039 - - - - ko00000 - - - PhoU JFBFHGED_01449 349741.Amuc_1309 1.39e-230 634.0 COG2017@1|root,COG2017@2|Bacteria,46TS8@74201|Verrucomicrobia,2IU12@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim JFBFHGED_01450 349741.Amuc_1310 5.17e-99 288.0 COG3133@1|root,COG3133@2|Bacteria,46XNK@74201|Verrucomicrobia,2IW9F@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycine zipper 2TM domain - - - ko:K06077 - - - - ko00000 - - - Rick_17kDa_Anti JFBFHGED_01452 349741.Amuc_1312 0.0 1552.0 COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia,2ITJG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Insulinase (Peptidase family M16) - - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C JFBFHGED_01453 349741.Amuc_1317 9.17e-70 210.0 COG1664@1|root,COG1664@2|Bacteria,46X69@74201|Verrucomicrobia,2IUN4@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin JFBFHGED_01454 349741.Amuc_1318 8.48e-119 341.0 COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF JFBFHGED_01455 349741.Amuc_1319 1.04e-161 454.0 COG0528@1|root,COG0528@2|Bacteria,46S4W@74201|Verrucomicrobia,2ITVK@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Amino acid kinase family pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase JFBFHGED_01456 349741.Amuc_1320 2.14e-179 503.0 COG0668@1|root,COG0668@2|Bacteria,46V1Y@74201|Verrucomicrobia,2IUI5@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,TM_helix JFBFHGED_01458 349741.Amuc_1321 9.91e-150 421.0 COG0450@1|root,COG0450@2|Bacteria,46TAE@74201|Verrucomicrobia,2ITGT@203494|Verrucomicrobiae 203494|Verrucomicrobiae O C-terminal domain of 1-Cys peroxiredoxin - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA JFBFHGED_01459 349741.Amuc_1322 0.0 1077.0 COG0733@1|root,COG0733@2|Bacteria,46XCF@74201|Verrucomicrobia,2IVFD@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Sodium:neurotransmitter symporter family - - - - - - - - - - - - SNF JFBFHGED_01460 349741.Amuc_1323 0.0 885.0 2AEXX@1|root,314VS@2|Bacteria,46YXW@74201|Verrucomicrobia,2IUHX@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01461 349741.Amuc_1324 2.48e-39 131.0 COG0361@1|root,COG0361@2|Bacteria 349741.Amuc_1324|- J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex - - - - - - - - - - - - - JFBFHGED_01462 349741.Amuc_2143 2.55e-05 53.9 COG4763@1|root,COG4763@2|Bacteria 2|Bacteria S transferase activity, transferring acyl groups other than amino-acyl groups - - - ko:K11941 - - - - ko00000,ko01000 - - - Acyl_transf_3 JFBFHGED_01463 349741.Amuc_1325 3.32e-141 399.0 COG0353@1|root,COG0353@2|Bacteria,46SU3@74201|Verrucomicrobia,2IU9C@203494|Verrucomicrobiae 203494|Verrucomicrobiae L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 JFBFHGED_01465 349741.Amuc_1327 2.7e-297 811.0 COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,2ITS2@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt JFBFHGED_01466 1396141.BATP01000009_gene2637 1.66e-185 540.0 COG1073@1|root,COG2755@1|root,COG1073@2|Bacteria,COG2755@2|Bacteria,46STE@74201|Verrucomicrobia,2IU0N@203494|Verrucomicrobiae 203494|Verrucomicrobiae E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2,Peptidase_S9 JFBFHGED_01467 349741.Amuc_1329 4.86e-91 268.0 COG0229@1|root,COG0229@2|Bacteria 2|Bacteria O peptide-methionine (R)-S-oxide reductase activity msrB - 1.8.4.11,1.8.4.12 ko:K07305,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR JFBFHGED_01468 349741.Amuc_1330 6.66e-240 661.0 COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia,2ITT1@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH JFBFHGED_01470 411476.BACOVA_03035 1.47e-163 466.0 COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,4NHRI@976|Bacteroidetes,2FRAG@200643|Bacteroidia,4APWS@815|Bacteroidaceae 976|Bacteroidetes K FR47-like protein - - - - - - - - - - - - Acetyltransf_1,HTH_27,MarR_2 JFBFHGED_01471 1105031.HMPREF1141_1151 6.26e-222 627.0 COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1V05G@1239|Firmicutes,25BEA@186801|Clostridia,36WEP@31979|Clostridiaceae 186801|Clostridia K AlkA N-terminal domain - - 3.2.2.21 ko:K13529 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD JFBFHGED_01472 742738.HMPREF9460_01177 5.5e-90 267.0 COG0350@1|root,COG0350@2|Bacteria,1V2MB@1239|Firmicutes,24HJ0@186801|Clostridia,26CPA@186813|unclassified Clostridiales 186801|Clostridia L 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K00567 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N JFBFHGED_01474 349741.Amuc_1379 7.73e-240 662.0 COG0842@1|root,COG0842@2|Bacteria,46SWI@74201|Verrucomicrobia,2IUJI@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 JFBFHGED_01475 349741.Amuc_1380 3.9e-232 642.0 COG0842@1|root,COG0842@2|Bacteria,46YUH@74201|Verrucomicrobia,2IVM6@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 JFBFHGED_01476 349741.Amuc_1381 0.0 1108.0 COG1131@1|root,COG1131@2|Bacteria,46SF6@74201|Verrucomicrobia,2IWKB@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JFBFHGED_01477 349741.Amuc_1382 2.27e-210 585.0 COG0845@1|root,COG0845@2|Bacteria,46VJJ@74201|Verrucomicrobia,2IUUW@203494|Verrucomicrobiae 203494|Verrucomicrobiae M HlyD family secretion protein - - - ko:K01993 - - - - ko00000 - - - HlyD_D23 JFBFHGED_01478 349741.Amuc_1383 0.0 1790.0 COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS - 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD JFBFHGED_01479 349741.Amuc_1384 3.03e-191 531.0 COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,2ITHZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae I CDP-alcohol phosphatidyltransferase - - 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_transf JFBFHGED_01480 349741.Amuc_1385 7.22e-114 327.0 2AW71@1|root,31N22@2|Bacteria,46X8R@74201|Verrucomicrobia,2IV10@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01481 349741.Amuc_1386 7.92e-185 515.0 COG0294@1|root,COG0294@2|Bacteria,46SSW@74201|Verrucomicrobia,2ITVR@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind JFBFHGED_01482 349741.Amuc_1387 0.0 1510.0 COG4485@1|root,COG4485@2|Bacteria 2|Bacteria M Bacterial membrane protein, YfhO - - - - - - - - - - - - YfhO JFBFHGED_01484 349741.Amuc_0371 1.5e-136 434.0 COG3292@1|root,COG3292@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Baseplate_J,CHB_HEX_C_1,Cu_amine_oxidN1,F5_F8_type_C,His_kinase,Reg_prop,Reprolysin_5,Sortilin-Vps10,VCBS,Y_Y_Y JFBFHGED_01487 349741.Amuc_1388 0.0 1117.0 COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,2IU3F@203494|Verrucomicrobiae 203494|Verrucomicrobiae I GcpE protein ispG - 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE JFBFHGED_01488 349741.Amuc_1389 1.65e-132 378.0 COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2IU7U@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ RmlD substrate binding domain - - - - - - - - - - - - adh_short_C2 JFBFHGED_01489 349741.Amuc_1390 2.73e-220 615.0 COG3274@1|root,COG3274@2|Bacteria 2|Bacteria S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_01490 349741.Amuc_1391 2.07e-270 744.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Abhydrolase_7,Hydrolase_4 JFBFHGED_01491 349741.Amuc_1392 9.94e-251 691.0 COG0304@1|root,COG0304@2|Bacteria,46YTP@74201|Verrucomicrobia,2IU8X@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ Beta-ketoacyl synthase, C-terminal domain - - - - - - - - - - - - Ketoacyl-synt_C,ketoacyl-synt JFBFHGED_01492 349741.Amuc_1393 3.07e-236 654.0 COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia,2ITJB@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Aminotransferase class I and II - - 2.3.1.47 ko:K00652 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R03210,R10124 RC00004,RC00039,RC02725 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_01493 537972.ABQU01000070_gene1391 4.33e-11 66.2 COG3295@1|root,COG3295@2|Bacteria,1RHV4@1224|Proteobacteria,42R84@68525|delta/epsilon subdivisions,2YNZI@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S integral membrane protein - - - - - - - - - - - - - JFBFHGED_01498 349741.Amuc_0036 2.16e-215 701.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_01501 349741.Amuc_1753 2.19e-29 112.0 COG2166@1|root,COG2166@2|Bacteria,46XA6@74201|Verrucomicrobia,2IUGW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Fe-S metabolism associated domain - - - ko:K02426 - - - - ko00000 - - - SufE JFBFHGED_01503 349741.Amuc_1396 0.0 1150.0 COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon JFBFHGED_01504 349741.Amuc_1397 1.75e-293 802.0 COG0124@1|root,COG0124@2|Bacteria,46V6Q@74201|Verrucomicrobia,2IWKW@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Histidyl-tRNA synthetase - - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His JFBFHGED_01505 556261.HMPREF0240_01798 4.84e-83 246.0 COG3871@1|root,COG3871@2|Bacteria,1V1KZ@1239|Firmicutes,25CPA@186801|Clostridia,36WYN@31979|Clostridiaceae 186801|Clostridia S Pyridoxamine 5'-phosphate oxidase like - - - - - - - - - - - - Putative_PNPOx,Pyrid_ox_like JFBFHGED_01506 349741.Amuc_1398 8.97e-170 474.0 COG0378@1|root,COG0378@2|Bacteria,46STP@74201|Verrucomicrobia 74201|Verrucomicrobia KO CobW/HypB/UreG, nucleotide-binding domain hypB - - ko:K04652 - - - - ko00000,ko03110 - - - cobW JFBFHGED_01507 349741.Amuc_1399 0.0 1360.0 COG0068@1|root,COG0068@2|Bacteria,46S89@74201|Verrucomicrobia,2IVG5@203494|Verrucomicrobiae 203494|Verrucomicrobiae O HypF finger - - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF JFBFHGED_01508 349741.Amuc_1400 3.64e-47 152.0 COG0298@1|root,COG0298@2|Bacteria,46T99@74201|Verrucomicrobia,2IWEC@203494|Verrucomicrobiae 203494|Verrucomicrobiae O HupF/HypC family - - - ko:K04653 - - - - ko00000 - - - HupF_HypC JFBFHGED_01509 349741.Amuc_1401 5.45e-237 654.0 COG0409@1|root,COG0409@2|Bacteria,46U5J@74201|Verrucomicrobia,2IV2C@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Hydrogenase formation hypA family - - - ko:K04654 - - - - ko00000 - - - HypD JFBFHGED_01510 349741.Amuc_1402 2.77e-229 633.0 COG0309@1|root,COG0309@2|Bacteria,46U2H@74201|Verrucomicrobia,2IVJI@203494|Verrucomicrobiae 203494|Verrucomicrobiae O AIR synthase related protein, N-terminal domain - - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C JFBFHGED_01511 349741.Amuc_1404 3.89e-246 678.0 COG0790@1|root,COG0790@2|Bacteria,46ZHX@74201|Verrucomicrobia,2IUWA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - Sel1 JFBFHGED_01512 349741.Amuc_1405 0.0 1195.0 COG0438@1|root,COG2908@1|root,COG0438@2|Bacteria,COG2908@2|Bacteria,46USQ@74201|Verrucomicrobia,2ITPS@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Metallophos JFBFHGED_01513 349741.Amuc_1406 0.0 1186.0 COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,2ITH0@203494|Verrucomicrobiae 203494|Verrucomicrobiae O MreB/Mbl protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 JFBFHGED_01514 349741.Amuc_1407 2.57e-60 186.0 COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,2IUHU@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS - - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 JFBFHGED_01515 349741.Amuc_1408 0.0 991.0 COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 JFBFHGED_01516 349741.Amuc_1410 0.0 1315.0 COG0306@1|root,COG0306@2|Bacteria 2|Bacteria P phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 JFBFHGED_01520 349741.Amuc_1412 9.39e-265 728.0 2BUZ4@1|root,32QBJ@2|Bacteria,46WND@74201|Verrucomicrobia,2IUIR@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - BBP2_2 JFBFHGED_01521 349741.Amuc_1413 0.0 1316.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia,2ITWV@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Chain length determinant protein - - - - - - - - - - - - AAA_31,Wzz JFBFHGED_01522 349741.Amuc_1414 5.72e-137 388.0 COG1596@1|root,COG1596@2|Bacteria,46T6Q@74201|Verrucomicrobia,2IUUF@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Polysaccharide biosynthesis/export protein - - - - - - - - - - - - Poly_export,SLBB JFBFHGED_01524 349741.Amuc_1416 1.07e-129 370.0 COG0632@1|root,COG0632@2|Bacteria,46SZF@74201|Verrucomicrobia,2IUHG@203494|Verrucomicrobiae 203494|Verrucomicrobiae L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N JFBFHGED_01525 349741.Amuc_1417 2.84e-241 663.0 COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,2ITXT@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N JFBFHGED_01526 349741.Amuc_1418 6.4e-279 764.0 COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,2ITXY@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Phosphoglycerate kinase pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK JFBFHGED_01527 349741.Amuc_1419 1.03e-162 464.0 28I0W@1|root,30QX6@2|Bacteria,46WYN@74201|Verrucomicrobia,2IUKF@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01529 349741.Amuc_1420 0.0 1179.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - GH97_C,GH97_N,Glyco_hydro_97 JFBFHGED_01530 349741.Amuc_1421 0.0 1419.0 COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 JFBFHGED_01531 1123070.KB899252_gene912 0.0 1119.0 COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia,2ITM9@203494|Verrucomicrobiae 203494|Verrucomicrobiae L TRCF - - - - - - - - - - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF JFBFHGED_01532 349741.Amuc_1423 6.82e-262 720.0 2EZMG@1|root,33SSM@2|Bacteria,46UUT@74201|Verrucomicrobia,2IU6Q@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01533 349741.Amuc_1424 0.0 1494.0 COG2271@1|root,COG3055@1|root,COG2271@2|Bacteria,COG3055@2|Bacteria,46SJ9@74201|Verrucomicrobia,2IU79@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 JFBFHGED_01534 349741.Amuc_1425 2.13e-205 570.0 COG3055@1|root,COG3055@2|Bacteria,46T14@74201|Verrucomicrobia,2IUGH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - - JFBFHGED_01536 349741.Amuc_1427 4.15e-191 530.0 COG1387@1|root,COG1387@2|Bacteria,46SMB@74201|Verrucomicrobia,2IU6X@203494|Verrucomicrobiae 203494|Verrucomicrobiae E PHP domain - - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - PHP JFBFHGED_01537 349741.Amuc_1428 1.18e-251 691.0 COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia,2IU3X@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Phosphate acetyl/butaryl transferase - - 2.3.1.8 ko:K00625 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - PTA_PTB JFBFHGED_01538 349741.Amuc_1429 3.99e-215 597.0 COG0037@1|root,COG0037@2|Bacteria,46T0B@74201|Verrucomicrobia,2IUJM@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3,TilS JFBFHGED_01539 349741.Amuc_1430 3.67e-59 183.0 COG0254@1|root,COG0254@2|Bacteria,46T4W@74201|Verrucomicrobia,2IUJ0@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L31 - - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 JFBFHGED_01543 314275.MADE_1012045 1.64e-05 57.8 COG0642@1|root,COG3292@1|root,COG4191@1|root,COG0642@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1T1YU@1236|Gammaproteobacteria,46D6C@72275|Alteromonadaceae 1236|Gammaproteobacteria T Y_Y_Y domain - - - ko:K20971 ko02025,map02025 - - - ko00000,ko00001,ko01001,ko02022 - - - CHASE,HATPase_c,HisKA,Hpt,MASE1,Reg_prop,Response_reg,Y_Y_Y JFBFHGED_01548 349741.Amuc_1435 4.38e-302 825.0 COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,2IU1R@203494|Verrucomicrobiae 203494|Verrucomicrobiae M UDP binding domain - - 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N JFBFHGED_01550 349741.Amuc_1436 2.04e-228 630.0 COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Catalyzes the reversible oxidation of malate to oxaloacetate - - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N JFBFHGED_01551 349741.Amuc_1437 0.0 1360.0 COG3408@1|root,COG3408@2|Bacteria 2|Bacteria G Glycogen debranching enzyme - - - - - - - - - - - - Bac_rhamnosid6H,DUF608,GDE_C JFBFHGED_01552 349741.Amuc_1438 0.0 1179.0 2DTCE@1|root,32UUZ@2|Bacteria,46Z6Q@74201|Verrucomicrobia,2IWPT@203494|Verrucomicrobiae 203494|Verrucomicrobiae M NPCBM/NEW2 domain - - - - - - - - - - - - NPCBM JFBFHGED_01553 349741.Amuc_1439 0.0 1536.0 COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,2ITQV@203494|Verrucomicrobiae 203494|Verrucomicrobiae M involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - - JFBFHGED_01554 349741.Amuc_1440 1.49e-143 405.0 COG0778@1|root,COG0778@2|Bacteria,46V9P@74201|Verrucomicrobia,2IU8H@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Nitroreductase family - - 1.5.1.34 ko:K10679 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase JFBFHGED_01555 349741.Amuc_1441 1.42e-172 483.0 COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,2IU67@203494|Verrucomicrobiae 203494|Verrucomicrobiae J RNA pseudouridylate synthase - - 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 JFBFHGED_01556 349741.Amuc_1442 3.02e-160 449.0 COG1187@1|root,COG1187@2|Bacteria,46V36@74201|Verrucomicrobia,2IUHB@203494|Verrucomicrobiae 203494|Verrucomicrobiae J RNA pseudouridylate synthase - - 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 JFBFHGED_01557 349741.Amuc_1443 9.05e-312 852.0 COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia,2ITH6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Tetratricopeptide repeat - - - - - - - - - - - - TPR_8 JFBFHGED_01558 1408428.JNJP01000051_gene3819 9.59e-65 204.0 COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria,2MBI2@213115|Desulfovibrionales 28221|Deltaproteobacteria Q PFAM isochorismatase hydrolase yddQ - - - - - - - - - - - Isochorismatase JFBFHGED_01559 349741.Amuc_1444 8.69e-106 306.0 COG0563@1|root,COG0563@2|Bacteria 2|Bacteria F adenylate kinase activity adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AAA_18,ADK JFBFHGED_01564 349741.Amuc_1445 1.3e-159 449.0 COG1126@1|root,COG1126@2|Bacteria,46UVK@74201|Verrucomicrobia,2IUC5@203494|Verrucomicrobiae 203494|Verrucomicrobiae E AAA domain, putative AbiEii toxin, Type IV TA system - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran JFBFHGED_01565 349741.Amuc_1446 0.0 869.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,46TJR@74201|Verrucomicrobia,2IU6P@203494|Verrucomicrobiae 203494|Verrucomicrobiae ET Bacterial periplasmic substrate-binding proteins - - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 JFBFHGED_01566 1297617.JPJD01000062_gene2821 1.44e-35 138.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24AI7@186801|Clostridia,268U1@186813|unclassified Clostridiales 186801|Clostridia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2,UDG JFBFHGED_01567 1158294.JOMI01000009_gene1068 5.79e-109 331.0 28IAS@1|root,2Z8DC@2|Bacteria,4NFA2@976|Bacteroidetes,2FSGV@200643|Bacteroidia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - EpsG JFBFHGED_01568 1158294.JOMI01000009_gene1067 2.16e-115 347.0 COG0438@1|root,COG0438@2|Bacteria,4NEX8@976|Bacteroidetes,2FNR2@200643|Bacteroidia 976|Bacteroidetes M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 JFBFHGED_01569 484018.BACPLE_00064 5.6e-85 256.0 COG2148@1|root,COG2148@2|Bacteria,4NF29@976|Bacteroidetes,2FNGF@200643|Bacteroidia,4ANCY@815|Bacteroidaceae 976|Bacteroidetes M Psort location CytoplasmicMembrane, score pglC - 2.7.8.36 ko:K15915 - - R10184 RC00002 ko00000,ko01000 - - - Bac_transf JFBFHGED_01570 272559.BF9343_0717 1.26e-171 499.0 COG0399@1|root,COG0399@2|Bacteria,4NFAI@976|Bacteroidetes,2FN8X@200643|Bacteroidia,4AKJ6@815|Bacteroidaceae 976|Bacteroidetes E Belongs to the DegT DnrJ EryC1 family epsN - - - - - - - - - - - DegT_DnrJ_EryC1 JFBFHGED_01571 411901.BACCAC_03067 6.39e-146 445.0 COG1086@1|root,COG1086@2|Bacteria,4NERY@976|Bacteroidetes,2FMAA@200643|Bacteroidia,4AKGY@815|Bacteroidaceae 976|Bacteroidetes GM Polysaccharide biosynthesis protein wbpM - - - - - - - - - - - CoA_binding_3,Polysacc_synt_2 JFBFHGED_01572 349741.Amuc_2077 3.37e-83 256.0 COG1596@1|root,COG1596@2|Bacteria 2|Bacteria M polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB JFBFHGED_01573 1122931.AUAE01000027_gene2427 2.14e-128 409.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,4NEXU@976|Bacteroidetes,2FM9K@200643|Bacteroidia,22W6W@171551|Porphyromonadaceae 976|Bacteroidetes DM Chain length determinant protein - - - - - - - - - - - - AAA_31,CbiA,GNVR,Wzz JFBFHGED_01574 357276.EL88_06645 4.41e-91 285.0 COG0438@1|root,COG0438@2|Bacteria,4NJ8R@976|Bacteroidetes,2G2SM@200643|Bacteroidia,4AW3U@815|Bacteroidaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JFBFHGED_01575 1004149.AFOE01000007_gene1405 1.31e-94 295.0 COG0438@1|root,COG0438@2|Bacteria,4NJ8R@976|Bacteroidetes,1I3MW@117743|Flavobacteriia 976|Bacteroidetes M glycosyl transferase family 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JFBFHGED_01576 1158294.JOMI01000009_gene1050 1.89e-57 196.0 COG0463@1|root,COG0463@2|Bacteria,4NS35@976|Bacteroidetes,2FT3C@200643|Bacteroidia 976|Bacteroidetes M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01577 1158294.JOMI01000009_gene1049 3.23e-130 385.0 COG2327@1|root,COG2327@2|Bacteria,4P0R4@976|Bacteroidetes,2FPZG@200643|Bacteroidia 976|Bacteroidetes S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans JFBFHGED_01578 1158294.JOMI01000009_gene1048 8.8e-88 277.0 COG4225@1|root,COG4225@2|Bacteria,4P1I5@976|Bacteroidetes,2FVYQ@200643|Bacteroidia 976|Bacteroidetes S Glycosyl Hydrolase Family 88 - - - - - - - - - - - - Glyco_hydro_88 JFBFHGED_01579 1158294.JOMI01000009_gene1047 1.51e-192 553.0 COG2244@1|root,COG2244@2|Bacteria,4NHVU@976|Bacteroidetes,2FNNQ@200643|Bacteroidia 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - - JFBFHGED_01580 357276.EL88_06605 1.42e-136 403.0 COG0438@1|root,COG0438@2|Bacteria,4NSKC@976|Bacteroidetes,2FNF6@200643|Bacteroidia,4ARFM@815|Bacteroidaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 JFBFHGED_01581 1158294.JOMI01000009_gene1045 4.25e-111 335.0 COG0438@1|root,COG0438@2|Bacteria,4NGDA@976|Bacteroidetes,2FMV5@200643|Bacteroidia 976|Bacteroidetes M Psort location Cytoplasmic, score - - - - - - - - - - - - Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1 JFBFHGED_01582 1122971.BAME01000074_gene5067 4.46e-86 271.0 COG1216@1|root,COG1216@2|Bacteria,4NKPU@976|Bacteroidetes,2FQ38@200643|Bacteroidia 976|Bacteroidetes M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glyco_transf_8,Glycos_transf_2 JFBFHGED_01583 1158294.JOMI01000009_gene1071 5.26e-116 348.0 COG0438@1|root,COG0438@2|Bacteria,4NK0S@976|Bacteroidetes,2FPH2@200643|Bacteroidia 976|Bacteroidetes M Glycosyltransferase, group 1 family - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 JFBFHGED_01584 1122971.BAME01000074_gene5068 7.3e-126 368.0 COG0463@1|root,COG0463@2|Bacteria,4NGTD@976|Bacteroidetes,2FPNS@200643|Bacteroidia,22ZF2@171551|Porphyromonadaceae 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01585 484018.BACPLE_00062 5.7e-73 239.0 COG0438@1|root,COG0438@2|Bacteria,4NGDA@976|Bacteroidetes,2FMV5@200643|Bacteroidia,4ANJH@815|Bacteroidaceae 976|Bacteroidetes M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glycos_transf_1 JFBFHGED_01586 1123226.KB899278_gene567 1.61e-36 142.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4IUTU@91061|Bacilli 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01587 484018.BACPLE_02384 2.62e-108 324.0 COG0793@1|root,COG0793@2|Bacteria,4NM5Z@976|Bacteroidetes,2FUBJ@200643|Bacteroidia,4ASVZ@815|Bacteroidaceae 976|Bacteroidetes M gag-polyprotein putative aspartyl protease - - - - - - - - - - - - Asp_protease_2 JFBFHGED_01588 634504.Bgr_03390 1.53e-27 115.0 COG4675@1|root,COG4675@2|Bacteria 2|Bacteria M tail collar domain protein - - - - - - - - - - - - Collar JFBFHGED_01590 349741.Amuc_1447 1.88e-249 684.0 COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia,2IU18@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Semialdehyde dehydrogenase, NAD binding domain argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC JFBFHGED_01591 349741.Amuc_1448 1.34e-298 815.0 COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia,2ITT9@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ JFBFHGED_01593 349741.Amuc_1450 4.79e-27 118.0 COG0790@1|root,COG0790@2|Bacteria,46SWR@74201|Verrucomicrobia,2IUT4@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Sel1-like repeats. - - - ko:K07126 - - - - ko00000 - - - Sel1 JFBFHGED_01595 349741.Amuc_1452 0.0 1518.0 COG0178@1|root,COG0178@2|Bacteria,46SEB@74201|Verrucomicrobia,2ITPE@203494|Verrucomicrobiae 203494|Verrucomicrobiae L ATPases associated with a variety of cellular activities - - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran JFBFHGED_01596 349741.Amuc_1453 5.39e-136 386.0 COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia,2IW9H@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin JFBFHGED_01597 349741.Amuc_1454 1.89e-117 338.0 COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia,2IUPK@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Polymer-forming cytoskeletal - - - - - - - - - - - - Bactofilin JFBFHGED_01598 349741.Amuc_1455 5.77e-223 617.0 2A0NC@1|root,30NSM@2|Bacteria,46XRM@74201|Verrucomicrobia,2IWFD@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01600 349741.Amuc_1457 2.72e-157 444.0 COG0106@1|root,COG0106@2|Bacteria,46U39@74201|Verrucomicrobia,2ITHN@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Histidine biosynthesis protein - - 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth JFBFHGED_01601 349741.Amuc_1458 1.74e-49 158.0 COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia,2IUWZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DUF167 - - - ko:K09131 - - - - ko00000 - - - DUF167 JFBFHGED_01602 349741.Amuc_1459 9.38e-105 305.0 COG0576@1|root,COG0576@2|Bacteria,46T79@74201|Verrucomicrobia,2IUHJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE - - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE JFBFHGED_01603 349741.Amuc_1460 4.57e-251 692.0 COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae 203494|Verrucomicrobiae O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG JFBFHGED_01604 349741.Amuc_1461 2.86e-161 453.0 COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia,2IUB0@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA JFBFHGED_01605 349741.Amuc_1462 3.71e-236 649.0 COG0546@1|root,COG1539@1|root,COG0546@2|Bacteria,COG1539@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae F HAD-hyrolase-like - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2,NUDIX JFBFHGED_01606 349741.Amuc_1463 0.0 1108.0 COG5434@1|root,COG5434@2|Bacteria,46X9H@74201|Verrucomicrobia,2IV3W@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Parallel beta-helix repeats - - - - - - - - - - - - - JFBFHGED_01607 349741.Amuc_1464 1.39e-211 585.0 COG1562@1|root,COG1562@2|Bacteria,46TVP@74201|Verrucomicrobia,2IU9Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Squalene/phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY JFBFHGED_01608 349741.Amuc_1465 8.18e-306 834.0 COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia,2IU66@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Peptidase S24-like - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 JFBFHGED_01609 349741.Amuc_1466 0.0 870.0 COG0277@1|root,COG0277@2|Bacteria,46SFA@74201|Verrucomicrobia,2ITGW@203494|Verrucomicrobiae 203494|Verrucomicrobiae C FAD linked oxidases, C-terminal domain - - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 JFBFHGED_01610 349741.Amuc_1467 4.97e-148 415.0 2B2BG@1|root,31UVN@2|Bacteria,46ZHA@74201|Verrucomicrobia,2IUTF@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01611 349741.Amuc_1468 5.38e-145 410.0 COG3319@1|root,COG3319@2|Bacteria 2|Bacteria Q amino acid activation for nonribosomal peptide biosynthetic process pks6 - - - - - - - - - - - Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt JFBFHGED_01612 349741.Amuc_1469 1.64e-153 433.0 2DKIU@1|root,309MI@2|Bacteria,46W7D@74201|Verrucomicrobia,2IUZM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF3485) - - - - - - - - - - - - DUF3485 JFBFHGED_01613 349741.Amuc_1470 1.34e-199 555.0 COG1269@1|root,COG1269@2|Bacteria,46VW2@74201|Verrucomicrobia,2IWJA@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Transmembrane exosortase (Exosortase_EpsH) - - - - - - - - - - - - Exosortase_EpsH JFBFHGED_01614 349741.Amuc_1471 8.86e-218 602.0 COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,2ITT3@203494|Verrucomicrobiae 203494|Verrucomicrobiae EF Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N JFBFHGED_01615 349741.Amuc_1472 3.27e-127 363.0 COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia,2IUP1@203494|Verrucomicrobiae 203494|Verrucomicrobiae J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C JFBFHGED_01617 349741.Amuc_1474 2.86e-139 393.0 COG0131@1|root,COG0131@2|Bacteria,46SR2@74201|Verrucomicrobia,2IU4M@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Imidazoleglycerol-phosphate dehydratase hisB - 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD JFBFHGED_01618 349741.Amuc_1475 1.98e-133 379.0 COG0118@1|root,COG0118@2|Bacteria,46V4G@74201|Verrucomicrobia,2IUAC@203494|Verrucomicrobiae 203494|Verrucomicrobiae E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase JFBFHGED_01619 272559.BF9343_3254 2.43e-205 588.0 COG1680@1|root,COG3439@1|root,COG1680@2|Bacteria,COG3439@2|Bacteria,4NJ5G@976|Bacteroidetes,2FPNT@200643|Bacteroidia,4APK3@815|Bacteroidaceae 976|Bacteroidetes V Domain of unknown function DUF302 - - - - - - - - - - - - Beta-lactamase,DUF302,TPR_2 JFBFHGED_01620 349741.Amuc_1476 7.18e-57 177.0 COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,2IUU4@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S6 - - - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 JFBFHGED_01622 349741.Amuc_1477 1.1e-196 546.0 COG1995@1|root,COG1995@2|Bacteria,46SNQ@74201|Verrucomicrobia,2ITTC@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Pyridoxal phosphate biosynthetic protein PdxA - - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA JFBFHGED_01625 349741.Amuc_1480 5.49e-214 593.0 COG1686@1|root,COG1686@2|Bacteria,46VPH@74201|Verrucomicrobia,2IU96@203494|Verrucomicrobiae 203494|Verrucomicrobiae M D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Peptidase_S11 JFBFHGED_01626 349741.Amuc_1481 3.36e-249 685.0 COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,2ITQA@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Phosphofructokinase - - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK JFBFHGED_01627 349741.Amuc_1482 1.36e-192 540.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane - - - - - - - - - - - - DUF805 JFBFHGED_01628 349741.Amuc_1483 7.69e-167 469.0 COG0428@1|root,COG0428@2|Bacteria 2|Bacteria P transporter zupT GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - iECIAI39_1322.ECIAI39_3536 Zip JFBFHGED_01629 349741.Amuc_1484 8.8e-187 525.0 COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,2IWPU@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Protein of unknown function, DUF255 - - - - - - - - - - - - Thioredoxin_2 JFBFHGED_01632 349741.Amuc_1487 6.05e-310 844.0 COG3977@1|root,COG3977@2|Bacteria,46YY9@74201|Verrucomicrobia,2ITU5@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class I and II - - 2.6.1.66 ko:K00835 ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130 - R01215 RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_01633 349741.Amuc_1488 1.28e-180 506.0 COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia,2IU44@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF1732) - - - - - - - - - - - - DUF1732,YicC_N JFBFHGED_01634 349741.Amuc_1489 2.57e-123 353.0 COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,2IU9Q@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Guanylate kinase homologues. - - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin JFBFHGED_01637 349741.Amuc_1490 0.0 1185.0 COG0471@1|root,COG0569@1|root,COG3273@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,COG3273@2|Bacteria,46TTA@74201|Verrucomicrobia,2IU1V@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Citrate transporter - - - - - - - - - - - - CitMHS,TrkA_C JFBFHGED_01638 349741.Amuc_1491 1.51e-199 553.0 COG0008@1|root,COG0008@2|Bacteria,46SQ3@74201|Verrucomicrobia,2ITGN@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class I (E and Q), catalytic domain - - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c JFBFHGED_01641 349741.Amuc_1494 5.9e-206 571.0 COG1575@1|root,COG1575@2|Bacteria,46V9A@74201|Verrucomicrobia,2IU5W@203494|Verrucomicrobiae 203494|Verrucomicrobiae H UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA JFBFHGED_01642 349741.Amuc_1495 7.68e-161 451.0 COG0710@1|root,COG0710@2|Bacteria,46VMG@74201|Verrucomicrobia,2IUIA@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Type I 3-dehydroquinase - - 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I JFBFHGED_01643 1396141.BATP01000030_gene3637 1.23e-90 302.0 COG2133@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3828@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae 2|Bacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH,ThuA JFBFHGED_01644 349741.Amuc_1497 5.94e-213 590.0 2BDDY@1|root,32730@2|Bacteria,46WKY@74201|Verrucomicrobia,2IWBU@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01645 349741.Amuc_1498 1.89e-158 444.0 COG1496@1|root,COG1496@2|Bacteria,46STZ@74201|Verrucomicrobia,2IUDE@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Multi-copper polyphenol oxidoreductase laccase - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 JFBFHGED_01646 349741.Amuc_1499 1.42e-162 456.0 COG3026@1|root,COG3026@2|Bacteria,46W95@74201|Verrucomicrobia,2IUUR@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Outer membrane lipoprotein-sorting protein - - - - - - - - - - - - LolA_like JFBFHGED_01647 349741.Amuc_1500 7.96e-213 590.0 COG0726@1|root,COG0726@2|Bacteria,46UKH@74201|Verrucomicrobia,2IU6W@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 JFBFHGED_01648 349741.Amuc_1501 0.0 1481.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,2ITYV@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4 - - SecD_SecF,Sec_GG JFBFHGED_01650 349741.Amuc_1503 7.16e-241 665.0 COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia,2IU6Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae NOU Type IV leader peptidase family - - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 JFBFHGED_01651 349741.Amuc_1504 1.41e-250 689.0 COG1611@1|root,COG1611@2|Bacteria,46SEG@74201|Verrucomicrobia,2ITGC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Possible lysine decarboxylase - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox JFBFHGED_01652 349741.Amuc_1505 1.4e-260 715.0 COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,2ITN6@203494|Verrucomicrobiae 203494|Verrucomicrobiae K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L JFBFHGED_01653 349741.Amuc_1506 2.84e-85 252.0 COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,2IUE5@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 JFBFHGED_01654 349741.Amuc_1507 1.11e-199 555.0 COG0331@1|root,COG0331@2|Bacteria,46SNS@74201|Verrucomicrobia,2ITTM@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Acyl transferase domain - - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 JFBFHGED_01657 349741.Amuc_1509 2.65e-150 424.0 COG0637@1|root,COG0637@2|Bacteria,46W9J@74201|Verrucomicrobia,2IUD3@203494|Verrucomicrobiae 203494|Verrucomicrobiae S HAD-hyrolase-like - - - - - - - - - - - - HAD_2 JFBFHGED_01658 349741.Amuc_1510 2.13e-270 744.0 COG0795@1|root,COG0795@2|Bacteria,46T0M@74201|Verrucomicrobia,2IU8Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Predicted permease YjgP/YjgQ family - - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ JFBFHGED_01659 349741.Amuc_1511 1.12e-248 684.0 COG1506@1|root,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - CBM_2,DUF2048,Peptidase_S9 JFBFHGED_01660 349741.Amuc_1512 1.12e-267 742.0 COG2885@1|root,COG2885@2|Bacteria,46T6J@74201|Verrucomicrobia,2IUNT@203494|Verrucomicrobiae 203494|Verrucomicrobiae M OmpA family - - - - - - - - - - - - OmpA JFBFHGED_01661 349741.Amuc_1513 1.99e-181 508.0 COG0561@1|root,COG0561@2|Bacteria,46SWT@74201|Verrucomicrobia,2IUQM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 JFBFHGED_01662 349741.Amuc_1514 0.0 1075.0 COG3064@1|root,COG3064@2|Bacteria,46TMJ@74201|Verrucomicrobia,2IVP4@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Peptidase M60-like family - - - - - - - - - - - - M60-like_N,Peptidase_M60 JFBFHGED_01663 349741.Amuc_1515 2.27e-286 784.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 JFBFHGED_01664 349741.Amuc_1516 0.0 1056.0 COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,46U96@74201|Verrucomicrobia,2ITU0@203494|Verrucomicrobiae 203494|Verrucomicrobiae KT Sigma factor PP2C-like phosphatases - - - - - - - - - - - - PAS_3,PAS_4,SpoIIE JFBFHGED_01665 349741.Amuc_1517 1.68e-156 439.0 COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2 JFBFHGED_01666 349741.Amuc_1518 2.81e-216 600.0 COG3568@1|root,COG3568@2|Bacteria,46Z38@74201|Verrucomicrobia,2IUCM@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos JFBFHGED_01667 349741.Amuc_1523 2.96e-162 456.0 COG4970@1|root,COG4970@2|Bacteria 2|Bacteria NU protein transport across the cell outer membrane - - - ko:K02457,ko:K08084 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15,3.A.15.2 - - GspH,N_methyl JFBFHGED_01668 349741.Amuc_1524 9.31e-147 417.0 2AW2C@1|root,31MX3@2|Bacteria,46X74@74201|Verrucomicrobia,2IUTK@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - N_methyl JFBFHGED_01669 349741.Amuc_1525 1.84e-240 662.0 COG4966@1|root,COG4966@2|Bacteria,46WRK@74201|Verrucomicrobia,2IUK5@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl JFBFHGED_01670 349741.Amuc_1526 2.68e-171 478.0 COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,2IUII@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Biotin/lipoate A/B protein ligase family - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB JFBFHGED_01671 349741.Amuc_1527 2.44e-220 609.0 COG0667@1|root,COG0667@2|Bacteria,46U3T@74201|Verrucomicrobia,2ITTY@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Aldo/keto reductase family - - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red JFBFHGED_01672 349741.Amuc_1528 0.0 1360.0 COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,2ITQY@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase JFBFHGED_01673 349741.Amuc_1531 0.0 883.0 COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,2ITH7@203494|Verrucomicrobiae 203494|Verrucomicrobiae EH Anthranilate synthase component I, N terminal region - - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind JFBFHGED_01674 349741.Amuc_1532 0.0 1016.0 COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia,2ITKX@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18,4.1.3.27 ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 JFBFHGED_01675 349741.Amuc_1533 1.57e-166 468.0 COG0134@1|root,COG0134@2|Bacteria,46V9B@74201|Verrucomicrobia,2ITZZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Indole-3-glycerol phosphate synthase - - 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS JFBFHGED_01676 349741.Amuc_1534 1.14e-143 406.0 COG0135@1|root,COG0135@2|Bacteria,46VS4@74201|Verrucomicrobia,2IUJV@203494|Verrucomicrobiae 203494|Verrucomicrobiae E N-(5'phosphoribosyl)anthranilate (PRA) isomerase trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI JFBFHGED_01677 349741.Amuc_1535 1.38e-275 754.0 COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae 203494|Verrucomicrobiae E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP JFBFHGED_01678 349741.Amuc_1536 1.03e-167 471.0 COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,2ITJI@203494|Verrucomicrobiae 203494|Verrucomicrobiae E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA JFBFHGED_01679 349741.Amuc_0892 1.38e-168 522.0 COG4625@1|root,COG4625@2|Bacteria,46WH4@74201|Verrucomicrobia 74201|Verrucomicrobia S pathogenesis - - - - - - - - - - - - - JFBFHGED_01681 349741.Amuc_1537 0.0 4868.0 COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter,ESPR,Haemagg_act,PATR JFBFHGED_01682 349741.Amuc_1538 8.13e-85 251.0 COG1764@1|root,COG1764@2|Bacteria 2|Bacteria O response to oxidative stress - - - - - - - - - - - - OsmC JFBFHGED_01683 469596.HMPREF9488_01101 3.27e-31 113.0 COG5470@1|root,COG5470@2|Bacteria,1VFMN@1239|Firmicutes,3VTSC@526524|Erysipelotrichia 526524|Erysipelotrichia S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 JFBFHGED_01684 349741.Amuc_1539 1.31e-267 734.0 COG2021@1|root,COG2021@2|Bacteria,46U58@74201|Verrucomicrobia,2ITGZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae E alpha/beta hydrolase fold - - 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 JFBFHGED_01685 349741.Amuc_1540 1.79e-23 92.0 COG0257@1|root,COG0257@2|Bacteria,46TAZ@74201|Verrucomicrobia,2IUUV@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L36 - - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 JFBFHGED_01688 349741.Amuc_1541 0.0 1105.0 COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia,2IUNU@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyltransferase family 9 (heptosyltransferase) - - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Glyco_transf_9,Lip_A_acyltrans JFBFHGED_01689 349741.Amuc_1542 7.12e-160 451.0 COG1180@1|root,COG1180@2|Bacteria,46YX6@74201|Verrucomicrobia,2IVDY@203494|Verrucomicrobiae 203494|Verrucomicrobiae C 4Fe-4S single cluster domain - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM JFBFHGED_01690 349741.Amuc_1543 0.0 1465.0 COG1882@1|root,COG1882@2|Bacteria,46XB7@74201|Verrucomicrobia,2IV9D@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Pyruvate formate lyase-like - - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like JFBFHGED_01691 349741.Amuc_1544 2.4e-149 424.0 COG2755@1|root,COG2755@2|Bacteria,46VAZ@74201|Verrucomicrobia,2IUIU@203494|Verrucomicrobiae 203494|Verrucomicrobiae E PFAM lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 JFBFHGED_01692 349741.Amuc_1546 3e-160 452.0 COG2755@1|root,COG2755@2|Bacteria,46VAZ@74201|Verrucomicrobia,2IUIU@203494|Verrucomicrobiae 203494|Verrucomicrobiae E PFAM lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 JFBFHGED_01693 349741.Amuc_1547 0.0 1164.0 COG4409@1|root,COG4409@2|Bacteria,46WSQ@74201|Verrucomicrobia,2IWA2@203494|Verrucomicrobiae 203494|Verrucomicrobiae EG BNR repeat-like domain - - - - - - - - - - - - BNR_2,Lipase_GDSL_2 JFBFHGED_01694 349741.Amuc_1548 2.07e-286 787.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus legA - 3.5.1.2 ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 - R00256,R01579 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Ank_2,Ank_4,Peptidase_M48 JFBFHGED_01695 349741.Amuc_1549 5.25e-171 481.0 COG0561@1|root,COG0561@2|Bacteria 2|Bacteria Q phosphatase activity supH - - - - - - - - - - - Hydrolase_3 JFBFHGED_01696 234267.Acid_4557 3.21e-79 253.0 COG2220@1|root,COG2220@2|Bacteria,3Y4D0@57723|Acidobacteria 57723|Acidobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 JFBFHGED_01697 349741.Amuc_1551 1.84e-83 246.0 COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA - 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 JFBFHGED_01698 349741.Amuc_1552 5.28e-262 719.0 COG0738@1|root,COG0738@2|Bacteria,46Z6R@74201|Verrucomicrobia,2IWPV@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 JFBFHGED_01700 675635.Psed_3468 0.000494 51.2 COG4974@1|root,COG4974@2|Bacteria,2GNXS@201174|Actinobacteria,4DYMV@85010|Pseudonocardiales 201174|Actinobacteria L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase JFBFHGED_01706 1206743.BAGM01000206_gene70 6.57e-47 165.0 28H9R@1|root,32DHK@2|Bacteria,2HJDR@201174|Actinobacteria,4G6GX@85025|Nocardiaceae 201174|Actinobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 JFBFHGED_01707 999419.HMPREF1077_02673 3.07e-14 70.1 2FB5H@1|root,343BU@2|Bacteria,4P5M8@976|Bacteroidetes,2FYMR@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - JFBFHGED_01708 1047013.AQSP01000114_gene682 3.43e-26 108.0 COG5340@1|root,COG5340@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - ko:K06919 - - - - ko00000 - - - AbiEi_4 JFBFHGED_01709 335543.Sfum_0218 1.39e-50 178.0 COG2253@1|root,COG2253@2|Bacteria,1PZRM@1224|Proteobacteria,42SAJ@68525|delta/epsilon subdivisions,2X5C7@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii JFBFHGED_01710 395963.Bind_2675 8.73e-74 231.0 COG1451@1|root,COG1451@2|Bacteria,1R8SX@1224|Proteobacteria,2VF8T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 JFBFHGED_01711 237609.PSAKL28_00140 0.0 915.0 COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,1RP2Q@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - HSDR_N,ResIII JFBFHGED_01712 1448139.AI20_00675 4.38e-101 315.0 COG0732@1|root,COG0732@2|Bacteria,1RHRY@1224|Proteobacteria,1S2N0@1236|Gammaproteobacteria 1236|Gammaproteobacteria L restriction hsdS - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S JFBFHGED_01713 1532557.JL37_20120 1.72e-287 818.0 COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,2VHBK@28216|Betaproteobacteria,3T1TQ@506|Alcaligenaceae 28216|Betaproteobacteria V HsdM N-terminal domain - - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase JFBFHGED_01714 1121456.ATVA01000013_gene1000 7.05e-76 239.0 COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,42PSS@68525|delta/epsilon subdivisions,2WKGZ@28221|Deltaproteobacteria,2MBKW@213115|Desulfovibrionales 28221|Deltaproteobacteria L Mrr N-terminal domain - - - ko:K07448 - - - - ko00000,ko02048 - - - HARE-HTH,Mrr_N,Mrr_cat JFBFHGED_01716 1396141.BATP01000001_gene5375 4.37e-27 108.0 COG2887@1|root,COG2887@2|Bacteria,46VRY@74201|Verrucomicrobia,2IVVM@203494|Verrucomicrobiae 203494|Verrucomicrobiae L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 JFBFHGED_01717 1396141.BATP01000001_gene5376 1.8e-35 130.0 2FDAI@1|root,345CE@2|Bacteria,46WE8@74201|Verrucomicrobia,2IVX3@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01727 349741.Amuc_1421 4.38e-50 192.0 COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126 - - - - ko00000 - - - Sel1 JFBFHGED_01728 690850.Desaf_3455 6.15e-127 375.0 COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,42MTT@68525|delta/epsilon subdivisions,2WM31@28221|Deltaproteobacteria,2M9SW@213115|Desulfovibrionales 28221|Deltaproteobacteria S Virulence protein RhuM family - - - - - - - - - - - - Virulence_RhuM JFBFHGED_01729 411471.SUBVAR_07192 2.49e-40 146.0 COG4245@1|root,COG4245@2|Bacteria,1UYN8@1239|Firmicutes,24PQD@186801|Clostridia,3WM02@541000|Ruminococcaceae 186801|Clostridia S von Willebrand factor type A domain - - - - - - - - - - - - VWA JFBFHGED_01730 649831.L083_0250 1.09e-06 59.7 COG0515@1|root,COG0515@2|Bacteria,2GMRN@201174|Actinobacteria,4D9NR@85008|Micromonosporales 201174|Actinobacteria KLT Lanthionine synthetase C-like protein - - - - - - - - - - - - LANC_like,Pkinase JFBFHGED_01734 349741.Amuc_1555 0.0 1346.0 COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,2ITYA@203494|Verrucomicrobiae 203494|Verrucomicrobiae L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB JFBFHGED_01736 349741.Amuc_1556 2.91e-38 128.0 COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,2IUW5@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L35 - - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p JFBFHGED_01737 349741.Amuc_1557 7.46e-79 235.0 COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,2IUFE@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT - - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 JFBFHGED_01738 1403819.BATR01000122_gene4267 3.34e-12 72.0 COG0526@1|root,COG0526@2|Bacteria,46X0G@74201|Verrucomicrobia,2IWD9@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Thioredoxin-like - - - - - - - - - - - - Thioredoxin_8 JFBFHGED_01739 349741.Amuc_1558 0.0 914.0 COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,2ITH1@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Peptidase family M50 - - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 JFBFHGED_01742 349741.Amuc_1561 0.0 1783.0 COG1074@1|root,COG1074@2|Bacteria,46SF0@74201|Verrucomicrobia,2ITYF@203494|Verrucomicrobiae 203494|Verrucomicrobiae L UvrD/REP helicase N-terminal domain - - - - - - - - - - - - PDDEXK_1,UvrD-helicase,UvrD_C JFBFHGED_01743 349741.Amuc_1562 0.0 1733.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,46SDQ@74201|Verrucomicrobia,2ITHI@203494|Verrucomicrobiae 203494|Verrucomicrobiae L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_1 JFBFHGED_01744 349741.Amuc_1563 1.82e-187 524.0 COG0697@1|root,COG0697@2|Bacteria 2|Bacteria EG spore germination MA20_36650 - - - - - - - - - - - EamA JFBFHGED_01745 349741.Amuc_1565 0.0 3245.0 COG2373@1|root,COG2373@2|Bacteria,46U24@74201|Verrucomicrobia,2IVD9@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Alpha-2-macroglobulin family - - - - - - - - - - - - A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl JFBFHGED_01746 349741.Amuc_1565 1.15e-101 333.0 COG2373@1|root,COG2373@2|Bacteria,46U24@74201|Verrucomicrobia,2IVD9@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Alpha-2-macroglobulin family - - - - - - - - - - - - A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl JFBFHGED_01747 349741.Amuc_1566 2.44e-267 734.0 COG1979@1|root,COG1979@2|Bacteria,46V6X@74201|Verrucomicrobia,2IWPW@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH JFBFHGED_01756 349741.Amuc_1570 2.54e-203 565.0 2EKXK@1|root,33EM4@2|Bacteria,46WCN@74201|Verrucomicrobia,2IUG6@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01757 349741.Amuc_1571 3.08e-124 357.0 COG1214@1|root,COG1214@2|Bacteria,46T3K@74201|Verrucomicrobia,2IUPV@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Glycoprotease family - - - - - - - - - - - - Peptidase_M22 JFBFHGED_01758 349741.Amuc_1572 5.12e-266 729.0 COG0372@1|root,COG0372@2|Bacteria,46SBV@74201|Verrucomicrobia,2ITKN@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Citrate synthase, C-terminal domain - - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt JFBFHGED_01759 1001530.BACE01000027_gene887 1.04e-77 238.0 COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1S57E@1236|Gammaproteobacteria,1Y2EM@135623|Vibrionales 135623|Vibrionales S Predicted membrane protein (DUF2238) - - - - - - - - - - - - DUF2238 JFBFHGED_01760 349741.Amuc_1574 1.83e-101 294.0 COG0219@1|root,COG0219@2|Bacteria,46SYZ@74201|Verrucomicrobia,2IUCK@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily - - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase JFBFHGED_01761 349741.Amuc_1575 4.62e-136 384.0 COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia,2IUC2@203494|Verrucomicrobiae 203494|Verrucomicrobiae L RNase_H superfamily - - - - - - - - - - - - RNase_H_2 JFBFHGED_01762 349741.Amuc_1576 1.35e-102 297.0 COG0691@1|root,COG0691@2|Bacteria,46VGJ@74201|Verrucomicrobia,2IUAH@203494|Verrucomicrobiae 203494|Verrucomicrobiae O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB - - ko:K03664 - - - - ko00000 - - - SmpB JFBFHGED_01763 349741.Amuc_1577 6.9e-41 135.0 COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae 203494|Verrucomicrobiae K RNA polymerase activity - - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 JFBFHGED_01764 349741.Amuc_1578 1.11e-114 330.0 COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia,2IU9S@203494|Verrucomicrobiae 203494|Verrucomicrobiae J RNA pseudouridylate synthase - - 5.4.99.20 ko:K06181 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 JFBFHGED_01765 349741.Amuc_1579 8.55e-188 523.0 28NXH@1|root,2ZBV3@2|Bacteria,46TF0@74201|Verrucomicrobia,2IUAE@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01766 349741.Amuc_1580 3.59e-102 296.0 COG0105@1|root,COG0105@2|Bacteria,46VKB@74201|Verrucomicrobia,2IUDM@203494|Verrucomicrobiae 203494|Verrucomicrobiae F NDK - - 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK JFBFHGED_01767 349741.Amuc_1581 3.71e-196 543.0 COG1216@1|root,COG1216@2|Bacteria,46W61@74201|Verrucomicrobia,2IWK3@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01768 349741.Amuc_1582 1.52e-211 586.0 COG0463@1|root,COG0463@2|Bacteria,46SPS@74201|Verrucomicrobia,2IUQ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_01769 1396141.BATP01000002_gene4824 1.85e-07 57.4 COG4968@1|root,COG4968@2|Bacteria,46WJ1@74201|Verrucomicrobia,2IUWN@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Prokaryotic N-terminal methylation motif - - - - - - - - - - - - N_methyl JFBFHGED_01770 349741.Amuc_1584 3.84e-280 768.0 COG1459@1|root,COG1459@2|Bacteria,46U60@74201|Verrucomicrobia,2IWMJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Type II secretion system (T2SS), protein F - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF JFBFHGED_01771 349741.Amuc_1585 0.0 1079.0 COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia,2ITMV@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Type II secretion system (T2SS), protein E, N-terminal domain - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N JFBFHGED_01772 349741.Amuc_1586 0.0 994.0 COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia,2IU2P@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Type II/IV secretion system protein - - - ko:K02652 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE,T2SSE_N JFBFHGED_01773 349741.Amuc_1587 7.17e-232 639.0 COG0042@1|root,COG0042@2|Bacteria,46SIG@74201|Verrucomicrobia,2ITHJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - - - - - - - - - - Dus JFBFHGED_01774 349741.Amuc_1588 2.39e-98 288.0 2CIV9@1|root,34A52@2|Bacteria,46W0H@74201|Verrucomicrobia,2IUYN@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Control of competence regulator ComK, YlbF/YmcA - - - - - - - - - - - - Com_YlbF JFBFHGED_01779 216142.LT40_18025 7.94e-39 164.0 COG3468@1|root,COG3468@2|Bacteria,1R9A8@1224|Proteobacteria,1RS0C@1236|Gammaproteobacteria 1236|Gammaproteobacteria MU Outer membrane autotransporter - - - - - - - - - - - - Autotransporter,Pertactin JFBFHGED_01780 349741.Amuc_1589 9.32e-273 747.0 COG0436@1|root,COG0436@2|Bacteria,46S4M@74201|Verrucomicrobia,2ITV6@203494|Verrucomicrobiae 203494|Verrucomicrobiae E DegT/DnrJ/EryC1/StrS aminotransferase family - - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_01781 349741.Amuc_1590 0.0 959.0 COG0728@1|root,COG0728@2|Bacteria,46SH1@74201|Verrucomicrobia,2IUHC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN JFBFHGED_01782 349741.Amuc_1591 3.89e-266 728.0 COG0615@1|root,COG0615@2|Bacteria,46TM5@74201|Verrucomicrobia,2IVDW@203494|Verrucomicrobiae 203494|Verrucomicrobiae IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like JFBFHGED_01783 349741.Amuc_1592 3.37e-155 437.0 COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,2IU40@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Iron/manganese superoxide dismutases, alpha-hairpin domain - - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N JFBFHGED_01784 349741.Amuc_1593 0.0 960.0 COG1649@1|root,COG1649@2|Bacteria,46UQU@74201|Verrucomicrobia,2ITMK@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Glycosyl hydrolase-like 10 - - - - - - - - - - - - GHL10 JFBFHGED_01785 349741.Amuc_1594 8.01e-155 437.0 COG1691@1|root,COG1691@2|Bacteria,46SQC@74201|Verrucomicrobia,2IUDP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S AIR carboxylase - - - ko:K06898 - - - - ko00000 - - - AIRC JFBFHGED_01786 349741.Amuc_1595 4.19e-160 452.0 COG1606@1|root,COG1606@2|Bacteria,46VAE@74201|Verrucomicrobia,2IUM5@203494|Verrucomicrobiae 203494|Verrucomicrobiae L tRNA processing - - - ko:K06864 - - - - ko00000 - - - ATP_bind_3,NAD_synthase JFBFHGED_01787 349741.Amuc_1596 8.3e-260 716.0 COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia,2IUEA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes larC - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 JFBFHGED_01788 349741.Amuc_1597 1.15e-233 644.0 COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia,2ITYJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Polyprenyl synthetase - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt JFBFHGED_01790 694427.Palpr_1540 2.08e-21 93.6 COG1357@1|root,COG1357@2|Bacteria,4NQ3B@976|Bacteroidetes,2FPSW@200643|Bacteroidia,22YNV@171551|Porphyromonadaceae 976|Bacteroidetes S Pentapeptide repeats (8 copies) - - - - - - - - - - - - Pentapeptide,Pentapeptide_4 JFBFHGED_01791 1268240.ATFI01000004_gene4373 1.32e-196 551.0 COG1162@1|root,COG1162@2|Bacteria,4NE24@976|Bacteroidetes,2FM8Z@200643|Bacteroidia,4AM8S@815|Bacteroidaceae 976|Bacteroidetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase JFBFHGED_01792 1235803.C825_05015 1.98e-145 415.0 COG0500@1|root,COG2226@2|Bacteria,4NH9S@976|Bacteroidetes,2FNVG@200643|Bacteroidia,22WZ0@171551|Porphyromonadaceae 976|Bacteroidetes Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 JFBFHGED_01793 349741.Amuc_1598 2.31e-312 852.0 COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae 203494|Verrucomicrobiae E POT family - - - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 JFBFHGED_01794 349741.Amuc_1599 0.0 1062.0 COG0760@1|root,COG0760@2|Bacteria,46T1I@74201|Verrucomicrobia,2IUT1@203494|Verrucomicrobiae 203494|Verrucomicrobiae O PPIC-type PPIASE domain - - 5.2.1.8 ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,SurA_N_3 JFBFHGED_01795 349741.Amuc_1600 1.23e-119 342.0 COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia,2IU6Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Pfam:DUF59 - - - - - - - - - - - - FeS_assembly_P JFBFHGED_01796 349741.Amuc_1601 6.58e-101 293.0 2AEKC@1|root,314G0@2|Bacteria,46XJ0@74201|Verrucomicrobia,2IW1N@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01798 349741.Amuc_1603 7.12e-196 545.0 COG2755@1|root,COG2755@2|Bacteria,46Z4Z@74201|Verrucomicrobia,2IUPG@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Domain of unknown function (DUF3472) - - - - - - - - - - - - DUF3472,DUF5077 JFBFHGED_01800 349741.Amuc_1604 5.83e-308 842.0 COG1007@1|root,COG1007@2|Bacteria,46ST5@74201|Verrucomicrobia,2IU1U@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M JFBFHGED_01801 349741.Amuc_1605 0.0 880.0 COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,2ITG7@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Proton-conducting membrane transporter - - 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M JFBFHGED_01802 349741.Amuc_1606 0.0 1123.0 COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,2ITQ9@203494|Verrucomicrobiae 203494|Verrucomicrobiae CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M,Proton_antipo_N JFBFHGED_01803 349741.Amuc_1607 6.01e-61 188.0 COG0713@1|root,COG0713@2|Bacteria,46SX4@74201|Verrucomicrobia,2IUN3@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK - 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 JFBFHGED_01804 349741.Amuc_1608 3.28e-129 372.0 COG0839@1|root,COG0839@2|Bacteria,46VSH@74201|Verrucomicrobia,2IUHV@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 JFBFHGED_01805 349741.Amuc_1609 3.2e-118 339.0 COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,2IU68@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI - 1.6.5.3 ko:K00338 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer4 JFBFHGED_01806 349741.Amuc_1610 2.26e-304 830.0 COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,2ITZ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh JFBFHGED_01807 349741.Amuc_1611 0.0 1097.0 COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,46S6S@74201|Verrucomicrobia,2ITJ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3 JFBFHGED_01808 349741.Amuc_1612 0.0 941.0 COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia,2ITYB@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB JFBFHGED_01809 349741.Amuc_1613 5.15e-136 385.0 COG1905@1|root,COG1905@2|Bacteria,46VMZ@74201|Verrucomicrobia,2IU8F@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Thioredoxin-like [2Fe-2S] ferredoxin - - 1.6.5.3 ko:K00334 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx JFBFHGED_01810 349741.Amuc_1614 5.73e-303 825.0 COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,2IU02@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa JFBFHGED_01811 349741.Amuc_1616 5.89e-302 829.0 COG0726@1|root,COG0726@2|Bacteria,46UVJ@74201|Verrucomicrobia,2IU4X@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 JFBFHGED_01812 349741.Amuc_1617 0.0 1030.0 COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,2ITKZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Putative Na+/H+ antiporter - - - - - - - - - - - - Na_H_antiport_3 JFBFHGED_01813 349741.Amuc_1618 2.58e-126 361.0 COG0307@1|root,COG0307@2|Bacteria,46SU1@74201|Verrucomicrobia,2IUAK@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Lumazine binding domain - - 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding JFBFHGED_01814 349741.Amuc_1619 2.67e-175 492.0 COG2264@1|root,COG2264@2|Bacteria,46SYY@74201|Verrucomicrobia,2ITXU@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein L11 methyltransferase (PrmA) - - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA JFBFHGED_01815 349741.Amuc_1621 0.0 1231.0 COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia,2ITJ3@203494|Verrucomicrobiae 203494|Verrucomicrobiae G 4-alpha-glucanotransferase - - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 JFBFHGED_01817 349741.Amuc_1623 0.0 875.0 COG0621@1|root,COG0621@2|Bacteria,46S5U@74201|Verrucomicrobia,2ITS9@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Uncharacterized protein family UPF0004 - - 2.8.4.4 ko:K14441 - - R10652 RC00003,RC03217 ko00000,ko01000,ko03009 - - - Radical_SAM,TRAM,UPF0004 JFBFHGED_01818 349741.Amuc_1624 0.0 885.0 COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia,2IU3S@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - ko:K07403 - - - - ko00000 - - - NfeD JFBFHGED_01819 349741.Amuc_1625 0.0 1062.0 COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,2ITUJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_2,Toprim_N,zf-CHC2 JFBFHGED_01820 349741.Amuc_1626 0.0 937.0 COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,2ITQW@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 JFBFHGED_01821 349741.Amuc_1627 6.53e-169 472.0 COG2173@1|root,COG2173@2|Bacteria,46VUM@74201|Verrucomicrobia,2IWEV@203494|Verrucomicrobiae 203494|Verrucomicrobiae M D-ala-D-ala dipeptidase - - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 JFBFHGED_01822 385682.AFSL01000098_gene5 8.1e-129 379.0 COG2259@1|root,COG2259@2|Bacteria,4NFR6@976|Bacteroidetes,2FMCV@200643|Bacteroidia,3XKK0@558415|Marinilabiliaceae 976|Bacteroidetes S TQO small subunit DoxA - - 1.8.5.2 ko:K16936,ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxA,DoxD JFBFHGED_01826 349741.Amuc_1630 0.0 1107.0 COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,2ITI6@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism - - - - - - - - - - - - LMWPc,LacAB_rpiB,SHMT JFBFHGED_01827 349741.Amuc_1631 0.0 1325.0 COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,2IU0C@203494|Verrucomicrobiae 203494|Verrucomicrobiae M tail specific protease - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - DUF3340,PDZ,Peptidase_S41 JFBFHGED_01828 349741.Amuc_1632 2.47e-194 542.0 COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia,2IUDS@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Cytidylyltransferase family - - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 JFBFHGED_01829 349741.Amuc_1633 0.0 1536.0 COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,2ITY8@203494|Verrucomicrobiae 203494|Verrucomicrobiae L ATP-dependent helicase C-terminal - - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C JFBFHGED_01830 349741.Amuc_1634 0.0 1380.0 COG0306@1|root,COG0306@2|Bacteria 2|Bacteria P phosphate transporter - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 JFBFHGED_01831 349741.Amuc_1635 7.66e-240 666.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity - - - - - - - - - - - - AhpC-TSA,Redoxin JFBFHGED_01832 349741.Amuc_1636 1.25e-303 831.0 COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia,2ITTG@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Poly A polymerase head domain - - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 JFBFHGED_01833 349741.Amuc_1637 0.0 1130.0 COG0366@1|root,COG0366@2|Bacteria,46URK@74201|Verrucomicrobia,2ITZW@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha amylase, catalytic domain - - - - - - - - - - - - Alpha-amylase JFBFHGED_01834 349741.Amuc_1638 0.0 1447.0 COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae 203494|Verrucomicrobiae NU Bacterial type II and III secretion system protein - - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin JFBFHGED_01835 349741.Amuc_1639 0.0 903.0 2AX66@1|root,31P4T@2|Bacteria,46XST@74201|Verrucomicrobia,2IWHH@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01836 349741.Amuc_1640 5.89e-173 482.0 COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,2IUKE@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF374) - - - ko:K09778 - - - - ko00000 - - - DUF374 JFBFHGED_01837 349741.Amuc_1641 1.1e-197 549.0 COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia,2ITSZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C JFBFHGED_01838 349741.Amuc_1642 6.57e-179 499.0 COG0623@1|root,COG0623@2|Bacteria,46ZBA@74201|Verrucomicrobia,2IW7X@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Enoyl-(Acyl carrier protein) reductase - - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 JFBFHGED_01840 349741.Amuc_1643 2.05e-167 471.0 COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia,2IUED@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat JFBFHGED_01841 349741.Amuc_1644 1.42e-251 692.0 COG1305@1|root,COG1305@2|Bacteria,46XFC@74201|Verrucomicrobia,2IVRS@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core JFBFHGED_01842 349741.Amuc_1645 1.35e-240 662.0 COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,2ITU4@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - ko:K05541 - - - - ko00000,ko01000,ko03016 - - - Dus JFBFHGED_01843 349741.Amuc_1646 5.27e-280 766.0 COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia,2IU0D@203494|Verrucomicrobiae 203494|Verrucomicrobiae IM LytB protein - - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB JFBFHGED_01845 349741.Amuc_1648 9.16e-41 135.0 COG0268@1|root,COG0268@2|Bacteria,46WWC@74201|Verrucomicrobia,2IV02@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Ribosomal protein S20 rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p JFBFHGED_01846 349741.Amuc_1649 4.17e-135 383.0 COG0637@1|root,COG0637@2|Bacteria,46VM3@74201|Verrucomicrobia,2IUCI@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 JFBFHGED_01847 349741.Amuc_1650 0.0 1197.0 COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,2ITSM@203494|Verrucomicrobiae 203494|Verrucomicrobiae EH Thiamine pyrophosphate enzyme, central domain - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N JFBFHGED_01849 349741.Amuc_1652 1.28e-170 479.0 COG0688@1|root,COG0688@2|Bacteria,46TND@74201|Verrucomicrobia,2ITXF@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Phosphatidylserine decarboxylase - - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase JFBFHGED_01850 349741.Amuc_1652 1.37e-12 66.2 COG0688@1|root,COG0688@2|Bacteria,46TND@74201|Verrucomicrobia,2ITXF@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Phosphatidylserine decarboxylase - - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase JFBFHGED_01852 349741.Amuc_1653 2.57e-141 400.0 COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,2IU4U@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Ribulose-phosphate 3 epimerase family - - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim JFBFHGED_01853 349741.Amuc_1654 0.0 1702.0 COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia,2ITTI@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Leucyl-tRNA synthetase, Domain 2 leuS - 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 JFBFHGED_01854 349741.Amuc_1655 0.0 1037.0 COG3119@1|root,COG3119@2|Bacteria,46SHT@74201|Verrucomicrobia,2IUAW@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase JFBFHGED_01856 349741.Amuc_1657 2.22e-277 759.0 COG0019@1|root,COG0019@2|Bacteria,46TXE@74201|Verrucomicrobia,2ITUI@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Pyridoxal-dependent decarboxylase, C-terminal sheet domain - - 4.1.1.96 ko:K13747 ko00330,ko01100,map00330,map01100 - R09081,R09082 RC00299 ko00000,ko00001,ko01000 - - - Orn_DAP_Arg_deC JFBFHGED_01857 349741.Amuc_1658 0.0 1284.0 COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia,2ITMU@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Pyridoxal-dependent decarboxylase, pyridoxal binding domain - - 4.1.1.19 ko:K01585 ko00330,ko01100,map00330,map01100 M00133 R00566 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N JFBFHGED_01858 349741.Amuc_1659 1.63e-259 711.0 COG0582@1|root,COG0582@2|Bacteria,46T2Q@74201|Verrucomicrobia,2IV0J@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase JFBFHGED_01860 1158294.JOMI01000004_gene3502 1.62e-187 555.0 COG3250@1|root,COG3250@2|Bacteria,4NEDF@976|Bacteroidetes,2FMTQ@200643|Bacteroidia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 2 family - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N JFBFHGED_01861 349741.Amuc_1666 0.0 2471.0 COG3250@1|root,COG3250@2|Bacteria,46XA3@74201|Verrucomicrobia,2IV61@203494|Verrucomicrobiae 2|Bacteria G Beta galactosidase small chain - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,RicinB_lectin_2 JFBFHGED_01862 349741.Amuc_1667 0.0 956.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,LRR_5,RicinB_lectin_2 JFBFHGED_01863 349741.Amuc_1667 4.51e-175 513.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,LRR_5,RicinB_lectin_2 JFBFHGED_01864 349741.Amuc_1668 0.0 867.0 COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia,2ITKR@203494|Verrucomicrobiae 2|Bacteria L MgsA AAA+ ATPase C terminal rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N JFBFHGED_01865 349741.Amuc_1669 0.0 959.0 COG3525@1|root,COG3525@2|Bacteria,46ZK1@74201|Verrucomicrobia,2IVDU@203494|Verrucomicrobiae 203494|Verrucomicrobiae G PFAM Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_01866 748247.AZKH_2522 3.94e-129 370.0 COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJFI@28216|Betaproteobacteria 28216|Betaproteobacteria Q isochorismatase hydrolase - - - - - - - - - - - - Isochorismatase JFBFHGED_01867 1397284.AYMN01000033_gene1140 6.36e-15 77.0 COG3224@1|root,COG3224@2|Bacteria,1QUU7@1224|Proteobacteria,1S1S3@1236|Gammaproteobacteria,401YQ@613|Serratia 1236|Gammaproteobacteria S Antibiotic biosynthesis monooxygenase - - - ko:K09932 - - - - ko00000 - - - ABM JFBFHGED_01868 240016.ABIZ01000001_gene322 0.0 980.0 COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 JFBFHGED_01869 931276.Cspa_c53010 4.84e-28 104.0 COG1359@1|root,COG1359@2|Bacteria,1VJ7Y@1239|Firmicutes,24RJ7@186801|Clostridia,36MX3@31979|Clostridiaceae 186801|Clostridia S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM JFBFHGED_01871 349741.Amuc_1671 1.85e-283 776.0 COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,2IV1Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions - - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK JFBFHGED_01873 349741.Amuc_1673 1.32e-250 689.0 COG1609@1|root,COG1609@2|Bacteria,46U1N@74201|Verrucomicrobia,2IUF7@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Periplasmic binding protein-like domain - - - - - - - - - - - - GntR,Peripla_BP_3 JFBFHGED_01876 349741.Amuc_1140 5.13e-10 60.5 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 JFBFHGED_01882 349741.Amuc_1678 6.03e-118 338.0 COG2087@1|root,COG2087@2|Bacteria 2|Bacteria H cobinamide kinase activity cobU GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568 2.7.1.156,2.7.7.62,6.3.5.10 ko:K02231,ko:K02232 ko00860,ko01100,map00860,map01100 M00122 R05221,R05222,R05225,R06558 RC00002,RC00010,RC00428,RC01302 ko00000,ko00001,ko00002,ko01000 - - iECIAI1_1343.ECIAI1_2074,iECSE_1348.ECSE_2277,iECW_1372.ECW_m2165,iETEC_1333.ETEC_2103,iEcE24377_1341.EcE24377A_2275,iEcSMS35_1347.EcSMS35_1131,iEcolC_1368.EcolC_1635,iLF82_1304.LF82_0337,iSDY_1059.SDY_2240,iWFL_1372.ECW_m2165 CobU JFBFHGED_01883 349741.Amuc_1679 1.11e-196 545.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - - - - - - - - - - - AP_endonuc_2 JFBFHGED_01884 349741.Amuc_1680 1.6e-163 459.0 COG0368@1|root,COG0368@2|Bacteria 2|Bacteria H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate cobS - 2.7.8.26 ko:K02233 ko00860,ko01100,map00860,map01100 M00122 R05223,R11174 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CobS JFBFHGED_01885 349741.Amuc_1681 7.45e-235 647.0 COG2038@1|root,COG2038@2|Bacteria 2|Bacteria H nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity cobT - 2.4.2.21 ko:K00768 ko00860,ko01100,map00860,map01100 M00122 R04148 RC00033,RC00063 ko00000,ko00001,ko00002,ko01000 - - - DBI_PRT JFBFHGED_01886 349741.Amuc_1682 5.65e-189 530.0 COG1270@1|root,COG1270@2|Bacteria,46XN1@74201|Verrucomicrobia,2IW87@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group cobD - 6.3.1.10 ko:K02227 ko00860,ko01100,map00860,map01100 M00122 R06529,R07302 RC00090,RC00096 ko00000,ko00001,ko00002,ko01000 - - - CobD_Cbib JFBFHGED_01887 349741.Amuc_1683 0.0 1491.0 COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,46UU7@74201|Verrucomicrobia,2IVRP@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation cobQ - - - - - - - - - - - GATase_3 JFBFHGED_01888 349741.Amuc_1684 0.0 1296.0 COG4206@1|root,COG4206@2|Bacteria,46Z6S@74201|Verrucomicrobia,2IWPX@203494|Verrucomicrobiae 203494|Verrucomicrobiae H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec JFBFHGED_01889 349741.Amuc_1685 0.0 1252.0 COG4166@1|root,COG4166@2|Bacteria,46UFF@74201|Verrucomicrobia,2ITVT@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 JFBFHGED_01890 349741.Amuc_1686 0.0 1580.0 COG1874@1|root,COG1874@2|Bacteria,46UVE@74201|Verrucomicrobia,2IU38@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolases family 35 - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - F5_F8_type_C,Glyco_hydro_35 JFBFHGED_01893 349741.Amuc_1687 3.19e-134 382.0 COG3637@1|root,COG3637@2|Bacteria 2|Bacteria M Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - ko:K16079 - - - - ko00000,ko02000 1.B.4.2.1 - - OMP_b-brl JFBFHGED_01894 349741.Amuc_1688 4.28e-286 786.0 COG0402@1|root,COG0402@2|Bacteria,46W01@74201|Verrucomicrobia,2IUMQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Amidohydrolase family - - 3.5.4.28,3.5.4.31 ko:K12960 ko00270,ko01100,map00270,map01100 - R09660 RC00477 ko00000,ko00001,ko01000 - - - Amidohydro_1 JFBFHGED_01895 349741.Amuc_1689 0.0 870.0 COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,2ITM3@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim JFBFHGED_01898 349741.Amuc_1692 1.93e-191 540.0 COG0508@1|root,COG0508@2|Bacteria,46SD3@74201|Verrucomicrobia,2ITTQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl JFBFHGED_01899 349741.Amuc_1693 0.0 1755.0 COG0567@1|root,COG0567@2|Bacteria,46S6G@74201|Verrucomicrobia,2ITMJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae C 2-oxoglutarate dehydrogenase C-terminal - - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr JFBFHGED_01900 349741.Amuc_1694 1.45e-236 652.0 COG1294@1|root,COG1294@2|Bacteria,46U7S@74201|Verrucomicrobia,2IUU8@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Cytochrome bd terminal oxidase subunit II - - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II JFBFHGED_01901 349741.Amuc_1695 0.0 907.0 COG1271@1|root,COG1271@2|Bacteria,46UI0@74201|Verrucomicrobia,2IU3N@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Cytochrome bd terminal oxidase subunit I - - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I JFBFHGED_01902 349741.Amuc_1696 3.02e-101 294.0 COG1376@1|root,COG1376@2|Bacteria,46VRV@74201|Verrucomicrobia,2IUQ8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD JFBFHGED_01903 349741.Amuc_1697 3.71e-95 278.0 COG0394@1|root,COG0394@2|Bacteria,46VB6@74201|Verrucomicrobia,2IUND@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Low molecular weight phosphatase family - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc JFBFHGED_01904 349741.Amuc_1698 2.15e-304 835.0 COG4252@1|root,COG4252@2|Bacteria,46Z6T@74201|Verrucomicrobia,2IUWF@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Chase2 domain - - - - - - - - - - - - - JFBFHGED_01905 349741.Amuc_1699 1.07e-210 583.0 COG3178@1|root,COG3178@2|Bacteria,46SU7@74201|Verrucomicrobia,2IU89@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Phosphotransferase enzyme family - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH JFBFHGED_01906 349741.Amuc_1700 1.64e-303 826.0 COG0133@1|root,COG0133@2|Bacteria,46XCI@74201|Verrucomicrobia,2IVFS@203494|Verrucomicrobiae 203494|Verrucomicrobiae E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP JFBFHGED_01907 349741.Amuc_1701 9.65e-90 264.0 COG1846@1|root,COG1846@2|Bacteria,46VKR@74201|Verrucomicrobia,2IUD2@203494|Verrucomicrobiae 203494|Verrucomicrobiae K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR JFBFHGED_01908 357276.EL88_02315 2.04e-65 204.0 COG3554@1|root,COG3554@2|Bacteria,4P154@976|Bacteroidetes,2G3A0@200643|Bacteroidia,4AQDV@815|Bacteroidaceae 976|Bacteroidetes - - - - - - - - - - - - - - - JFBFHGED_01909 349741.Amuc_1703 1.16e-102 298.0 COG1528@1|root,COG1528@2|Bacteria,46WDU@74201|Verrucomicrobia,2IUMT@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Ferritin-like domain - - 1.16.3.2 ko:K02217 - - - - ko00000,ko01000 - - - Ferritin JFBFHGED_01910 349741.Amuc_1704 0.0 874.0 2F6YF@1|root,33ZEH@2|Bacteria,46VWD@74201|Verrucomicrobia,2IU9D@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_01911 349741.Amuc_1705 2.09e-97 285.0 COG0251@1|root,COG0251@2|Bacteria,46VPS@74201|Verrucomicrobia,2IUFV@203494|Verrucomicrobiae 203494|Verrucomicrobiae J YjgF/chorismate_mutase-like, putative endoribonuclease - - - - - - - - - - - - YjgF_endoribonc JFBFHGED_01914 349741.Amuc_1706 4.06e-128 368.0 COG2949@1|root,COG2949@2|Bacteria,46T0H@74201|Verrucomicrobia,2IUEI@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DUF218 domain - - - ko:K03748 - - - - ko00000 - - - DUF218 JFBFHGED_01915 471870.BACINT_03646 4e-99 293.0 COG1051@1|root,COG1051@2|Bacteria,4NK6B@976|Bacteroidetes,2FPVU@200643|Bacteroidia,4APTD@815|Bacteroidaceae 976|Bacteroidetes F COG COG1051 ADP-ribose pyrophosphatase - - - - - - - - - - - - HAD_2,NUDIX,Nudix_N JFBFHGED_01917 349741.Amuc_2080 5.37e-58 191.0 COG2148@1|root,COG2148@2|Bacteria,46UQE@74201|Verrucomicrobia,2IUN5@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf JFBFHGED_01918 349741.Amuc_2077 2.83e-119 348.0 COG1596@1|root,COG1596@2|Bacteria 2|Bacteria M polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB JFBFHGED_01919 349741.Amuc_2078 1.05e-210 621.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46V4D@74201|Verrucomicrobia 74201|Verrucomicrobia DM PFAM lipopolysaccharide biosynthesis protein gumC - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz JFBFHGED_01920 1123008.KB905712_gene728 1.23e-171 501.0 COG0534@1|root,COG0534@2|Bacteria,4P00R@976|Bacteroidetes,2G04Y@200643|Bacteroidia,2325G@171551|Porphyromonadaceae 976|Bacteroidetes V Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - MatE JFBFHGED_01922 1042376.AFPK01000070_gene742 5.33e-106 320.0 2DBCR@1|root,2Z8FA@2|Bacteria,4NH3U@976|Bacteroidetes,1I7GE@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - JFBFHGED_01923 694427.Palpr_2322 1.07e-133 398.0 COG0438@1|root,COG0438@2|Bacteria,4NNU7@976|Bacteroidetes,2FU7N@200643|Bacteroidia,230JB@171551|Porphyromonadaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_4_2,Glycos_transf_1 JFBFHGED_01924 1185876.BN8_06526 1.37e-39 143.0 COG0110@1|root,COG0110@2|Bacteria,4NQE2@976|Bacteroidetes,47QQ1@768503|Cytophagia 976|Bacteroidetes S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - Hexapep,Hexapep_2 JFBFHGED_01925 1123008.KB905712_gene751 3.23e-61 213.0 28IIC@1|root,2Z8JF@2|Bacteria,4NJ7P@976|Bacteroidetes,2FUES@200643|Bacteroidia,22ZK6@171551|Porphyromonadaceae 976|Bacteroidetes - - - - - - - - - - - - - - - JFBFHGED_01926 504487.JCM19302_993 6.54e-87 267.0 COG1216@1|root,COG1216@2|Bacteria,4NP1S@976|Bacteroidetes,1I3I3@117743|Flavobacteriia 976|Bacteroidetes S Pfam Glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 JFBFHGED_01927 985255.APHJ01000021_gene1345 2.77e-56 190.0 2DMF5@1|root,32UGW@2|Bacteria,4P0ZX@976|Bacteroidetes,1I8FA@117743|Flavobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - JFBFHGED_01928 28115.HR11_01315 4.41e-42 158.0 COG0438@1|root,COG0438@2|Bacteria,4NPHK@976|Bacteroidetes,2FSM3@200643|Bacteroidia,2307K@171551|Porphyromonadaceae 976|Bacteroidetes M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glycos_transf_1 JFBFHGED_01929 1434325.AZQN01000002_gene722 1.4e-21 94.0 COG0110@1|root,COG0110@2|Bacteria,4NHX5@976|Bacteroidetes,47SK1@768503|Cytophagia 976|Bacteroidetes S Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep JFBFHGED_01930 483216.BACEGG_02326 2.15e-143 421.0 COG0438@1|root,COG0438@2|Bacteria,4NQIQ@976|Bacteroidetes,2FT7M@200643|Bacteroidia,4ARU4@815|Bacteroidaceae 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 JFBFHGED_01931 483215.BACFIN_06836 8.66e-92 283.0 COG1922@1|root,COG1922@2|Bacteria,4NHZY@976|Bacteroidetes,2G2SR@200643|Bacteroidia,4AW40@815|Bacteroidaceae 976|Bacteroidetes M Glycosyl transferase WecB/TagA/CpsF family - - 2.4.1.187 ko:K05946 ko05111,map05111 - - - ko00000,ko00001,ko01000,ko01003 - GT26 - Glyco_tran_WecB JFBFHGED_01932 349741.Amuc_1591 3.63e-193 543.0 COG0615@1|root,COG0615@2|Bacteria,46TM5@74201|Verrucomicrobia,2IVDW@203494|Verrucomicrobiae 203494|Verrucomicrobiae IM Cytidylyltransferase-like - - - - - - - - - - - - CTP_transf_like JFBFHGED_01934 1122931.AUAE01000018_gene3833 5.81e-267 754.0 COG3669@1|root,COG3669@2|Bacteria,4NEDX@976|Bacteroidetes,2FNFV@200643|Bacteroidia,22WIN@171551|Porphyromonadaceae 976|Bacteroidetes G F5 8 type C domain protein - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos,F5_F8_type_C JFBFHGED_01943 349741.Amuc_1710 0.0 1341.0 COG0514@1|root,COG0514@2|Bacteria,46U82@74201|Verrucomicrobia,2ITT4@203494|Verrucomicrobiae 203494|Verrucomicrobiae L RQC - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind JFBFHGED_01945 349741.Amuc_1378 8.06e-39 151.0 COG4974@1|root,COG4974@2|Bacteria 2|Bacteria L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_5,Phage_integrase JFBFHGED_01962 1236504.HMPREF2132_11055 7.75e-51 169.0 COG0827@1|root,COG0827@2|Bacteria,4P741@976|Bacteroidetes,2FVWI@200643|Bacteroidia 976|Bacteroidetes L DNA restriction-modification system - - - - - - - - - - - - - JFBFHGED_01963 1124654.G9L6A8_9CAUD 5.45e-45 159.0 4QDG8@10239|Viruses,4QX18@35237|dsDNA viruses no RNA stage,4QSE7@28883|Caudovirales,4QNUU@10744|Podoviridae 10744|Podoviridae - - - - - - - - - - - - - - - JFBFHGED_01969 580331.Thit_1395 2.5e-35 144.0 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia,42HVJ@68295|Thermoanaerobacterales 186801|Clostridia L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - JFBFHGED_01971 278957.ABEA03000019_gene1900 2.76e-20 100.0 COG4383@1|root,COG4383@2|Bacteria 2|Bacteria L Mu-like prophage protein gp29 - - - - - - - - - - - - DUF935,Phage_Mu_F JFBFHGED_01986 1031288.AXAA01000056_gene787 1.45e-11 67.4 COG0860@1|root,COG0860@2|Bacteria,1V7NN@1239|Firmicutes,25BDQ@186801|Clostridia,36WEN@31979|Clostridiaceae 186801|Clostridia M Ami_3 - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,Cu_amine_oxidN1,SH3_3 JFBFHGED_01996 349741.Amuc_1712 1.3e-207 574.0 COG0074@1|root,COG0074@2|Bacteria,46TRM@74201|Verrucomicrobia,2ITVZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA JFBFHGED_01997 349741.Amuc_1713 1.72e-266 731.0 COG0045@1|root,COG0045@2|Bacteria,46TDG@74201|Verrucomicrobia,2ITNQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA JFBFHGED_01998 349741.Amuc_1714 4.53e-284 779.0 COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD - 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh JFBFHGED_01999 1121015.N789_00090 3.12e-18 86.7 COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S401@1236|Gammaproteobacteria,1X396@135614|Xanthomonadales 135614|Xanthomonadales K Transcriptional regulator - - - - - - - - - - - - TetR_N JFBFHGED_02000 349741.Amuc_1715 2.29e-198 551.0 COG0385@1|root,COG0385@2|Bacteria,46U9V@74201|Verrucomicrobia 74201|Verrucomicrobia S Bile acid - - - ko:K03453 - - - - ko00000 2.A.28 - - - JFBFHGED_02003 349741.Amuc_1718 3.05e-69 209.0 2BK4J@1|root,32EI6@2|Bacteria,46X8G@74201|Verrucomicrobia,2IV09@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02004 349741.Amuc_1719 9.58e-304 831.0 COG1570@1|root,COG1570@2|Bacteria,46SCN@74201|Verrucomicrobia,2ITK4@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 JFBFHGED_02005 349741.Amuc_1720 5.78e-277 771.0 COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,2ITYM@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ AMP-binding enzyme - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C JFBFHGED_02006 349741.Amuc_1720 1.11e-199 572.0 COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,2ITYM@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ AMP-binding enzyme - - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C JFBFHGED_02007 349741.Amuc_0584 1.11e-244 814.0 COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter,ESPR,Haemagg_act,PATR JFBFHGED_02008 349741.Amuc_1723 0.0 2840.0 COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria,46Z6U@74201|Verrucomicrobia 74201|Verrucomicrobia S pathogenesis - - - - - - - - - - - - PATR JFBFHGED_02009 349741.Amuc_1725 4.34e-158 445.0 COG3884@1|root,COG3884@2|Bacteria,46WFX@74201|Verrucomicrobia 74201|Verrucomicrobia I Acyl-ACP thioesterase - - - - - - - - - - - - Acyl-ACP_TE JFBFHGED_02010 349741.Amuc_1726 8.37e-221 611.0 COG0451@1|root,COG0451@2|Bacteria,46TPV@74201|Verrucomicrobia,2IWKZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M 3-beta hydroxysteroid dehydrogenase/isomerase family - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd JFBFHGED_02011 349741.Amuc_1727 0.0 1002.0 COG0642@1|root,COG2205@2|Bacteria,46Z6V@74201|Verrucomicrobia,2IWPY@203494|Verrucomicrobiae 203494|Verrucomicrobiae T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA JFBFHGED_02012 349741.Amuc_1728 4.07e-105 307.0 COG0745@1|root,COG0745@2|Bacteria,46UZH@74201|Verrucomicrobia,2IVRM@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C JFBFHGED_02014 349741.Amuc_1730 4.49e-233 642.0 COG0113@1|root,COG0113@2|Bacteria,46S91@74201|Verrucomicrobia,2ITPG@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Delta-aminolevulinic acid dehydratase - - 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD JFBFHGED_02016 349741.Amuc_1732 0.0 1246.0 COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia,2ITM8@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD JFBFHGED_02017 349741.Amuc_1733 1.18e-139 395.0 COG0290@1|root,COG0290@2|Bacteria,46SU6@74201|Verrucomicrobia,2IUB3@203494|Verrucomicrobiae 203494|Verrucomicrobiae J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins - - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N JFBFHGED_02018 1235797.C816_00196 4.36e-41 140.0 COG0454@1|root,COG0456@2|Bacteria,1V1WF@1239|Firmicutes,24N1J@186801|Clostridia 186801|Clostridia K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 JFBFHGED_02019 349741.Amuc_1736 7.52e-255 703.0 COG2311@1|root,COG2311@2|Bacteria,46VK7@74201|Verrucomicrobia,2IUSC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF1624,DUF418 JFBFHGED_02020 349741.Amuc_1737 3.53e-258 710.0 COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,2ITI1@203494|Verrucomicrobiae 203494|Verrucomicrobiae I 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal dxr - 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom JFBFHGED_02022 349741.Amuc_1738 7.6e-118 337.0 COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia,2IUBC@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD - 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like JFBFHGED_02023 349741.Amuc_1739 7.27e-60 186.0 COG1186@1|root,COG1186@2|Bacteria,46T84@74201|Verrucomicrobia,2IUUG@203494|Verrucomicrobiae 203494|Verrucomicrobiae J RF-1 domain - - - - - - - - - - - - RF-1 JFBFHGED_02024 349741.Amuc_1740 2.93e-108 314.0 2B2U2@1|root,31VEM@2|Bacteria,46X86@74201|Verrucomicrobia,2IUZ0@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02025 349741.Amuc_1741 1.63e-314 858.0 COG4284@1|root,COG4284@2|Bacteria,46YX5@74201|Verrucomicrobia,2ITK7@203494|Verrucomicrobiae 203494|Verrucomicrobiae G UTP--glucose-1-phosphate uridylyltransferase - - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - UDPGP JFBFHGED_02026 349741.Amuc_1742 1.36e-144 411.0 COG4106@1|root,COG4106@2|Bacteria 2|Bacteria FG trans-aconitate 2-methyltransferase activity - - 2.1.1.144,2.1.1.197 ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 M00572 R09543 RC00003,RC00460 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23,Methyltransf_25 JFBFHGED_02028 349741.Amuc_1744 8.82e-114 329.0 COG1729@1|root,COG1729@2|Bacteria 2|Bacteria S protein trimerization - - - - - - - - - - - - TPR_16,TPR_2,TPR_6,TPR_8 JFBFHGED_02029 349741.Amuc_1746 4.77e-190 532.0 COG3475@1|root,COG3475@2|Bacteria 2|Bacteria M LICD family - - - ko:K07271 - - - - ko00000,ko01000 - - - LicD JFBFHGED_02030 349741.Amuc_1747 7.16e-177 506.0 COG0615@1|root,COG0673@1|root,COG0615@2|Bacteria,COG0673@2|Bacteria,46UQX@74201|Verrucomicrobia,2IW4Z@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Oxidoreductase family, NAD-binding Rossmann fold - - 2.7.7.15 ko:K00968 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 M00090 R01890,R02590 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C JFBFHGED_02031 1121101.HMPREF1532_01681 1.03e-96 295.0 COG2423@1|root,COG2423@2|Bacteria,4PJ6G@976|Bacteroidetes,2FR7I@200643|Bacteroidia,4AT1P@815|Bacteroidaceae 976|Bacteroidetes E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall JFBFHGED_02032 349741.Amuc_1749 0.0 1121.0 COG0079@1|root,COG1213@1|root,COG0079@2|Bacteria,COG1213@2|Bacteria 2|Bacteria M nucleotidyl transferase cobD - 2.6.1.9,2.7.7.74,4.1.1.81 ko:K00817,ko:K04720,ko:K07281 ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243,R06530,R09669 RC00002,RC00006,RC00517,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2,NTP_transf_3 JFBFHGED_02033 349741.Amuc_1750 1.32e-32 122.0 COG3475@1|root,COG3475@2|Bacteria 2|Bacteria M LICD family - - - ko:K07271 - - - - ko00000,ko01000 - - - LicD JFBFHGED_02034 349741.Amuc_1750 3.88e-147 421.0 COG3475@1|root,COG3475@2|Bacteria 2|Bacteria M LICD family - - - ko:K07271 - - - - ko00000,ko01000 - - - LicD JFBFHGED_02035 349741.Amuc_1751 0.0 1332.0 COG0296@1|root,COG0296@2|Bacteria,46SH5@74201|Verrucomicrobia,2ITSF@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha amylase, C-terminal all-beta domain - - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 JFBFHGED_02037 349741.Amuc_1753 1.9e-89 263.0 COG2166@1|root,COG2166@2|Bacteria,46XA6@74201|Verrucomicrobia,2IUGW@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Fe-S metabolism associated domain - - - ko:K02426 - - - - ko00000 - - - SufE JFBFHGED_02038 349741.Amuc_1754 1.42e-216 598.0 COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia,2IU2R@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline - - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N JFBFHGED_02039 349741.Amuc_1755 0.0 1055.0 COG3119@1|root,COG3119@2|Bacteria,46SHT@74201|Verrucomicrobia,2IUAW@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Sulfatase - - - - - - - - - - - - DUF4976,Sulfatase JFBFHGED_02040 349741.Amuc_1756 0.0 1113.0 COG1080@1|root,COG1080@2|Bacteria,46TX4@74201|Verrucomicrobia,2ITIJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) - - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C JFBFHGED_02041 349741.Amuc_1757 8.72e-53 166.0 COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,2IUM2@203494|Verrucomicrobiae 203494|Verrucomicrobiae G PTS HPr component phosphorylation site - - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr JFBFHGED_02042 349741.Amuc_1758 4.41e-219 605.0 COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia,2ITXV@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N JFBFHGED_02043 349741.Amuc_1759 1.79e-316 863.0 COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia,2ITIW@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 JFBFHGED_02044 349741.Amuc_1760 5.87e-198 550.0 COG1131@1|root,COG1131@2|Bacteria,46SHV@74201|Verrucomicrobia,2ITWN@203494|Verrucomicrobiae 203494|Verrucomicrobiae V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran JFBFHGED_02045 349741.Amuc_1761 3.31e-129 368.0 COG0212@1|root,COG0212@2|Bacteria,46T35@74201|Verrucomicrobia,2IUUD@203494|Verrucomicrobiae 203494|Verrucomicrobiae H 5-formyltetrahydrofolate cyclo-ligase family - - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig JFBFHGED_02046 349741.Amuc_1762 0.0 1063.0 COG0699@1|root,COG0699@2|Bacteria,46W58@74201|Verrucomicrobia,2IUZ4@203494|Verrucomicrobiae 203494|Verrucomicrobiae S 50S ribosome-binding GTPase - - - - - - - - - - - - Dynamin_N JFBFHGED_02047 349741.Amuc_1763 7.59e-150 423.0 COG0325@1|root,COG0325@2|Bacteria,46SV2@74201|Verrucomicrobia,2IU7Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Alanine racemase, N-terminal domain - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N JFBFHGED_02048 349741.Amuc_1764 2.55e-124 355.0 COG1678@1|root,COG1678@2|Bacteria,46VUF@74201|Verrucomicrobia,2IUUZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Uncharacterized ACR, COG1678 - - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 JFBFHGED_02049 349741.Amuc_1765 1.12e-171 483.0 COG1376@1|root,COG1376@2|Bacteria,46VQZ@74201|Verrucomicrobia,2IUGD@203494|Verrucomicrobiae 203494|Verrucomicrobiae S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD JFBFHGED_02050 349741.Amuc_1766 0.0 1002.0 COG1215@1|root,COG1215@2|Bacteria,46SF7@74201|Verrucomicrobia,2ITZU@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase family group 2 - - - - - - - - - - - - Glyco_tranf_2_3 JFBFHGED_02051 349741.Amuc_1767 5.83e-194 540.0 2F4CA@1|root,33X2V@2|Bacteria,46VIX@74201|Verrucomicrobia,2IUA1@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02052 349741.Amuc_1768 1.92e-80 239.0 COG2967@1|root,COG2967@2|Bacteria,46T44@74201|Verrucomicrobia,2IUUM@203494|Verrucomicrobiae 203494|Verrucomicrobiae P ApaG domain - - - ko:K06195 - - - - ko00000 - - - DUF525 JFBFHGED_02053 349741.Amuc_1769 8.11e-90 290.0 COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae 203494|Verrucomicrobiae L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N JFBFHGED_02054 349741.Amuc_1769 0.0 1843.0 COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae 203494|Verrucomicrobiae L SNF2 family N-terminal domain - - - - - - - - - - - - Helicase_C,SNF2_N JFBFHGED_02055 349741.Amuc_1770 1.13e-103 300.0 COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia,2IU8W@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Lrp/AsnC ligand binding domain - - - - - - - - - - - - AsnC_trans_reg,HTH_24 JFBFHGED_02056 349741.Amuc_1771 4.42e-272 745.0 COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,2ITGM@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Cys/Met metabolism PLP-dependent enzyme - - - ko:K10907 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_02057 349741.Amuc_1772 4.33e-188 522.0 COG1266@1|root,COG1266@2|Bacteria,46VN3@74201|Verrucomicrobia,2IU8B@203494|Verrucomicrobiae 203494|Verrucomicrobiae S CAAX protease self-immunity - - - - - - - - - - - - Abi JFBFHGED_02058 349741.Amuc_1773 1.79e-138 393.0 COG1434@1|root,COG1434@2|Bacteria,46XE9@74201|Verrucomicrobia,2IVN5@203494|Verrucomicrobiae 203494|Verrucomicrobiae S DUF218 domain - - - - - - - - - - - - DUF218 JFBFHGED_02059 349741.Amuc_1774 0.0 1047.0 COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Anticodon binding domain - - 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b JFBFHGED_02074 411483.FAEPRAA2165_03407 0.000109 52.0 COG4388@1|root,COG4388@2|Bacteria,1TRUA@1239|Firmicutes,24BB0@186801|Clostridia,3WNA2@541000|Ruminococcaceae 186801|Clostridia S Mu-like prophage I protein - - - - - - - - - - - - Mu-like_Pro JFBFHGED_02076 1121448.DGI_0942 3.9e-148 438.0 COG4373@1|root,COG4373@2|Bacteria,1N2KG@1224|Proteobacteria,42QD9@68525|delta/epsilon subdivisions,2WMJN@28221|Deltaproteobacteria,2MGMJ@213115|Desulfovibrionales 28221|Deltaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C JFBFHGED_02082 679935.Alfi_0758 1.26e-89 272.0 2DBHG@1|root,2Z99H@2|Bacteria,4NFUR@976|Bacteroidetes,2G1U9@200643|Bacteroidia,22UT0@171550|Rikenellaceae 976|Bacteroidetes - - - - - - - - - - - - - - - JFBFHGED_02099 349741.Amuc_2063 5.94e-60 185.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - MarR,MarR_2 JFBFHGED_02100 349741.Amuc_2062 1.02e-137 390.0 2ECX1@1|root,336U7@2|Bacteria,46WXQ@74201|Verrucomicrobia,2IWIP@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02102 349741.Amuc_2060 0.0 1062.0 28HPK@1|root,2Z7XJ@2|Bacteria,46VI6@74201|Verrucomicrobia,2IVHI@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Bacteriophage head to tail connecting protein - - - - - - - - - - - - Head-tail_con JFBFHGED_02104 349741.Amuc_2058 2.46e-156 444.0 2B73I@1|root,3204H@2|Bacteria,46WXA@74201|Verrucomicrobia,2IWC2@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02106 349741.Amuc_2057 1.35e-107 311.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - AhpC-TSA,Thioredoxin_7 JFBFHGED_02107 349741.Amuc_2056 2.3e-71 215.0 COG1633@1|root,COG1633@2|Bacteria 2|Bacteria S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - - - - - - - - - - COQ7,Rubrerythrin JFBFHGED_02108 349741.Amuc_2055 1.93e-68 207.0 COG1633@1|root,COG1633@2|Bacteria 2|Bacteria S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - - - - - - - - - - COQ7,Rubrerythrin JFBFHGED_02109 349741.Amuc_2054 4.71e-102 296.0 COG1433@1|root,COG1433@2|Bacteria 2|Bacteria S nitrogen fixation - - - - - - - - - - - - C_GCAxxG_C_C JFBFHGED_02110 349741.Amuc_2053 2.22e-141 400.0 COG0586@1|root,COG0586@2|Bacteria 2|Bacteria S FtsZ-dependent cytokinesis dedA - - - - - - - - - - - SNARE_assoc JFBFHGED_02111 349741.Amuc_2052 1.12e-250 690.0 COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,2ITSK@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB JFBFHGED_02112 349741.Amuc_2051 0.0 891.0 COG0334@1|root,COG0334@2|Bacteria,46YXD@74201|Verrucomicrobia,2ITNI@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase - - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N JFBFHGED_02114 349741.Amuc_2050 1.6e-249 684.0 COG1943@1|root,COG1943@2|Bacteria,46V2P@74201|Verrucomicrobia,2IVVU@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Transposase IS200 like - - - - - - - - - - - - Y1_Tnp JFBFHGED_02115 349741.Amuc_2049 0.0 1101.0 COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia,2IU71@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - CBS,Voltage_CLC JFBFHGED_02116 349741.Amuc_2048 5.09e-79 236.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.202 ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 JFBFHGED_02118 349741.Amuc_2046 1.46e-146 412.0 COG4112@1|root,COG4112@2|Bacteria,46V3C@74201|Verrucomicrobia,2IU8G@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02119 349741.Amuc_2045 0.0 1333.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Cadherin,Calx-beta,FG-GAP,Flg_new,Laminin_G_3,Lipase_GDSL_2,M60-like_N,PA14,Peptidase_M60 JFBFHGED_02121 349741.Amuc_2043 1.82e-311 852.0 COG1538@1|root,COG1538@2|Bacteria,46SFR@74201|Verrucomicrobia,2IUDN@203494|Verrucomicrobiae 203494|Verrucomicrobiae MU Outer membrane efflux protein - - - ko:K18139 ko01501,ko02024,map01501,map02024 M00642,M00643,M00647,M00718,M00768,M00822 - - ko00000,ko00001,ko00002,ko01504,ko02000 1.B.17,2.A.6.2 - - OEP JFBFHGED_02122 349741.Amuc_2042 0.0 1977.0 COG0841@1|root,COG0841@2|Bacteria,46SDN@74201|Verrucomicrobia,2IWND@203494|Verrucomicrobiae 203494|Verrucomicrobiae V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran JFBFHGED_02123 349741.Amuc_2041 1.64e-268 739.0 COG0845@1|root,COG0845@2|Bacteria,46X9T@74201|Verrucomicrobia,2IVR2@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2 JFBFHGED_02124 349741.Amuc_2040 0.0 1226.0 COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,2ITQT@203494|Verrucomicrobiae 2|Bacteria E Peptidase family M3 prlC - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 JFBFHGED_02125 349741.Amuc_2039 0.0 1035.0 COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae 203494|Verrucomicrobiae E LeuA allosteric (dimerisation) domain - - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer JFBFHGED_02128 349741.Amuc_2038 6.78e-42 137.0 2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,2IUSJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S PurA ssDNA and RNA-binding protein - - - - - - - - - - - - PurA JFBFHGED_02129 349741.Amuc_2037 3.39e-253 695.0 COG0489@1|root,COG0489@2|Bacteria,46SAV@74201|Verrucomicrobia,2ITW9@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Iron-sulfur cluster assembly protein - - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA JFBFHGED_02130 349741.Amuc_2036 0.0 879.0 COG0534@1|root,COG0534@2|Bacteria,46UTM@74201|Verrucomicrobia,2IU2M@203494|Verrucomicrobiae 203494|Verrucomicrobiae V MatE - - - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE JFBFHGED_02132 448385.sce5155 4.69e-178 505.0 COG0524@1|root,COG0524@2|Bacteria,1QNWF@1224|Proteobacteria 1224|Proteobacteria G PFAM PfkB domain protein - - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB JFBFHGED_02133 1080067.BAZH01000004_gene3984 3.41e-132 401.0 COG1312@1|root,COG1312@2|Bacteria,1MWYD@1224|Proteobacteria,1RR0Q@1236|Gammaproteobacteria,3WX4P@544|Citrobacter 1236|Gammaproteobacteria G D-mannonate dehydratase (UxuA) uxuA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008198,GO:0008927,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019585,GO:0019752,GO:0030145,GO:0032787,GO:0033554,GO:0042839,GO:0042840,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0072329,GO:1901575 4.2.1.8 ko:K01686 ko00040,ko01100,map00040,map01100 M00061 R05606 RC00543 ko00000,ko00001,ko00002,ko01000 - - iECED1_1282.ECED1_5204 UxuA JFBFHGED_02134 1122194.AUHU01000007_gene201 1.33e-181 523.0 COG1904@1|root,COG1904@2|Bacteria,1MVRI@1224|Proteobacteria,1RMRR@1236|Gammaproteobacteria,464VQ@72275|Alteromonadaceae 1236|Gammaproteobacteria G Glucuronate isomerase uxaC GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 ko:K01812 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000 - - iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528 UxaC JFBFHGED_02135 357804.Ping_0129 3.26e-59 192.0 COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,1RPDF@1236|Gammaproteobacteria,2QIQU@267894|Psychromonadaceae 1236|Gammaproteobacteria G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase JFBFHGED_02136 504472.Slin_5749 3.93e-137 407.0 COG2271@1|root,COG2271@2|Bacteria,4NE7R@976|Bacteroidetes,47JBJ@768503|Cytophagia 976|Bacteroidetes G PFAM Major Facilitator Superfamily - - - ko:K08191 - - - - ko00000,ko02000 2.A.1.14.2 - - MFS_1 JFBFHGED_02138 349741.Amuc_2034 0.0 991.0 COG5016@1|root,COG5016@2|Bacteria,46UNW@74201|Verrucomicrobia,2IWQ0@203494|Verrucomicrobiae 203494|Verrucomicrobiae C HMGL-like - - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA JFBFHGED_02139 349741.Amuc_2033 0.0 908.0 COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Phospholipase D. Active site motifs. - - - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2 JFBFHGED_02140 349741.Amuc_2032 8.82e-203 560.0 COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia,2ITI7@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Thymidylate synthase - - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt JFBFHGED_02141 349741.Amuc_2031 2.65e-98 286.0 COG0262@1|root,COG0262@2|Bacteria,46T19@74201|Verrucomicrobia,2IUNY@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Dihydrofolate reductase - - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 JFBFHGED_02142 349741.Amuc_2030 0.0 1905.0 COG0841@1|root,COG0841@2|Bacteria,46U0U@74201|Verrucomicrobia,2ITVP@203494|Verrucomicrobiae 203494|Verrucomicrobiae V AcrB/AcrD/AcrF family - - - - - - - - - - - - ACR_tran JFBFHGED_02143 349741.Amuc_2029 1.09e-252 695.0 COG0845@1|root,COG0845@2|Bacteria,46U1A@74201|Verrucomicrobia,2IV1B@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Biotin-lipoyl like - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2 JFBFHGED_02144 349741.Amuc_2028 1.68e-98 287.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - MarR,MarR_2 JFBFHGED_02146 349741.Amuc_2027 1.06e-224 621.0 COG0418@1|root,COG0418@2|Bacteria,46TXB@74201|Verrucomicrobia,2IVIQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Amidohydrolase - - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - - JFBFHGED_02147 349741.Amuc_2026 3.07e-154 432.0 COG0491@1|root,COG0491@2|Bacteria,46T2E@74201|Verrucomicrobia,2IUFH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B JFBFHGED_02148 349741.Amuc_2025 1.46e-282 773.0 COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia,2ITQU@203494|Verrucomicrobiae 203494|Verrucomicrobiae L helicase superfamily c-terminal domain - - - - - - - - - - - - DEAD,Helicase_C JFBFHGED_02149 349741.Amuc_2024 3.19e-106 307.0 COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC JFBFHGED_02150 349741.Amuc_2023 7.42e-108 312.0 2FKI6@1|root,34C5C@2|Bacteria,46W75@74201|Verrucomicrobia,2IUZH@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02151 1122971.BAME01000009_gene1221 1.04e-79 243.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity M1-674 - 3.4.21.107 ko:K01173,ko:K04771 ko01503,ko02020,ko04210,map01503,map02020,map04210 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03029,ko03110 - - - Trypsin,Trypsin_2 JFBFHGED_02152 349741.Amuc_2021 1.78e-51 165.0 COG1051@1|root,COG1051@2|Bacteria,46VUY@74201|Verrucomicrobia,2IUIE@203494|Verrucomicrobiae 203494|Verrucomicrobiae F NUDIX domain - - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX JFBFHGED_02153 526218.Sterm_2308 5.05e-261 739.0 COG2015@1|root,COG2015@2|Bacteria,37C6B@32066|Fusobacteria 32066|Fusobacteria Q PFAM beta-lactamase domain protein - - - - - - - - - - - - Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B JFBFHGED_02154 349741.Amuc_2021 2.28e-97 284.0 COG1051@1|root,COG1051@2|Bacteria,46VUY@74201|Verrucomicrobia,2IUIE@203494|Verrucomicrobiae 203494|Verrucomicrobiae F NUDIX domain - - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX JFBFHGED_02155 349741.Amuc_2020 3.04e-235 648.0 COG1703@1|root,COG1703@2|Bacteria,46TIM@74201|Verrucomicrobia,2IV0T@203494|Verrucomicrobiae 203494|Verrucomicrobiae E ArgK protein - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK JFBFHGED_02156 349741.Amuc_2019 8.25e-317 868.0 COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae 2|Bacteria G Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_02157 349741.Amuc_2018 9.19e-315 863.0 COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae 2|Bacteria G Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_02159 349741.Amuc_1335 0.0 912.0 COG5511@1|root,COG5511@2|Bacteria,46XJW@74201|Verrucomicrobia,2IW3H@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Phage portal protein, lambda family - - - - - - - - - - - - Phage_portal_2 JFBFHGED_02160 349741.Amuc_1336 1.43e-156 441.0 COG0616@1|root,COG0616@2|Bacteria,46V3T@74201|Verrucomicrobia,2IWET@203494|Verrucomicrobiae 203494|Verrucomicrobiae OU Peptidase family S49 - - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 JFBFHGED_02162 349741.Amuc_1338 3.08e-154 438.0 2B7EM@1|root,320ID@2|Bacteria,46XRV@74201|Verrucomicrobia,2IWFU@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02169 349741.Amuc_1348 0.0 1058.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - DUF1542,DUF349,DUF4446,FIVAR,GA,Gram_pos_anchor,PhageMin_Tail JFBFHGED_02175 349741.Amuc_1354 2.99e-91 270.0 COG2826@1|root,COG2826@2|Bacteria,46XS5@74201|Verrucomicrobia,2IWG7@203494|Verrucomicrobiae 203494|Verrucomicrobiae L transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - - JFBFHGED_02176 349741.Amuc_1355 0.0 1125.0 COG5525@1|root,COG5525@2|Bacteria,46VZ2@74201|Verrucomicrobia,2IUJ9@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Phage terminase large subunit (GpA) - - - - - - - - - - - - Terminase_GpA JFBFHGED_02181 349741.Amuc_1360 4.13e-104 304.0 COG3926@1|root,COG3926@2|Bacteria 2|Bacteria S Glycosyl hydrolase 108 - - - - - - - - - - - - Glyco_hydro_108,PG_binding_3,Peptidase_M15_4 JFBFHGED_02199 1236504.HMPREF2132_11055 1.27e-33 121.0 COG0827@1|root,COG0827@2|Bacteria,4P741@976|Bacteroidetes,2FVWI@200643|Bacteroidia 976|Bacteroidetes L DNA restriction-modification system - - - - - - - - - - - - - JFBFHGED_02200 520999.PROVALCAL_00744 7.36e-76 238.0 COG0338@1|root,COG0338@2|Bacteria,1QDNE@1224|Proteobacteria,1T9QN@1236|Gammaproteobacteria,3ZA38@586|Providencia 1236|Gammaproteobacteria L D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K06223 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 - - - MethyltransfD12 JFBFHGED_02202 349741.Amuc_1378 1.07e-283 777.0 COG4974@1|root,COG4974@2|Bacteria 2|Bacteria L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_5,Phage_integrase JFBFHGED_02204 349741.Amuc_2017 1.62e-92 272.0 COG3600@1|root,COG3600@2|Bacteria 2|Bacteria K Phage-associated protein gepA - - - - - - - - - - - DUF4065 JFBFHGED_02205 1453496.AT03_08625 9.73e-106 383.0 COG2911@1|root,COG3266@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,COG4625@2|Bacteria,1QXSX@1224|Proteobacteria,1T3I1@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q domain, Protein - - - - - - - - - - - - - JFBFHGED_02206 1453496.AT03_08625 4.69e-92 335.0 COG2911@1|root,COG3266@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3266@2|Bacteria,COG4625@2|Bacteria,1QXSX@1224|Proteobacteria,1T3I1@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q domain, Protein - - - - - - - - - - - - - JFBFHGED_02207 349741.Amuc_2016 5.19e-154 437.0 COG2145@1|root,COG2145@2|Bacteria 2|Bacteria H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK JFBFHGED_02208 349741.Amuc_2015 4.59e-124 355.0 COG0352@1|root,COG0352@2|Bacteria,46T6K@74201|Verrucomicrobia 2|Bacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17 ko:K00788,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 M00127 R03223,R03471,R03472,R04509,R10712 RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU38290 TMP-TENI JFBFHGED_02209 349741.Amuc_2014 5.01e-203 564.0 COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Pyridoxal-phosphate dependent enzyme - - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP JFBFHGED_02210 349741.Amuc_2013 4.26e-264 728.0 COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Cys/Met metabolism PLP-dependent enzyme - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP JFBFHGED_02211 349741.Amuc_2012 1.31e-93 274.0 COG1959@1|root,COG1959@2|Bacteria,46X6R@74201|Verrucomicrobia,2IURA@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Transcriptional regulator - - - - - - - - - - - - Rrf2 JFBFHGED_02212 349741.Amuc_2011 3.19e-263 721.0 COG0787@1|root,COG0787@2|Bacteria,46SM1@74201|Verrucomicrobia,2IU27@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N JFBFHGED_02213 349741.Amuc_2003 1.44e-165 466.0 COG0569@1|root,COG0569@2|Bacteria 2|Bacteria P domain protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 JFBFHGED_02214 349741.Amuc_2002 0.0 1146.0 COG0326@1|root,COG0326@2|Bacteria,46U76@74201|Verrucomicrobia,2IU3I@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Hsp90 protein htpG - - ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 - - - ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 - - - HATPase_c_3,HSP90 JFBFHGED_02215 349741.Amuc_2001 0.0 1190.0 COG4166@1|root,COG4166@2|Bacteria 2|Bacteria E transmembrane transport - - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - F5_F8_type_C,M60-like_N,Peptidase_M60,SBP_bac_5 JFBFHGED_02217 216816.GS08_04475 1.28e-80 246.0 COG1305@1|root,COG1305@2|Bacteria,2GM42@201174|Actinobacteria,4D0N1@85004|Bifidobacteriales 201174|Actinobacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core JFBFHGED_02218 1077285.AGDG01000039_gene3992 2.3e-85 257.0 COG3059@1|root,COG3059@2|Bacteria,4NG9V@976|Bacteroidetes,2FMSP@200643|Bacteroidia,4AN0N@815|Bacteroidaceae 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 9.46 ykgB - - - - - - - - - - - DUF417 JFBFHGED_02219 349741.Amuc_2000 5.03e-264 725.0 COG2807@1|root,COG2807@2|Bacteria,46XKN@74201|Verrucomicrobia,2IW54@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Major Facilitator Superfamily - - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 JFBFHGED_02220 349741.Amuc_1999 1.76e-235 649.0 COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,2ITTX@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Aminoacyl tRNA synthetase class II, N-terminal domain pheS - 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d JFBFHGED_02221 349741.Amuc_1998 0.0 1455.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,46SDG@74201|Verrucomicrobia,2ITHP@203494|Verrucomicrobiae 203494|Verrucomicrobiae J B3/4 domain pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind JFBFHGED_02222 349741.Amuc_1998 7.54e-34 129.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,46SDG@74201|Verrucomicrobia,2ITHP@203494|Verrucomicrobiae 203494|Verrucomicrobiae J B3/4 domain pheT - 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind JFBFHGED_02223 349741.Amuc_1997 4.89e-231 638.0 28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia,2IU3Q@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF4105) - - - - - - - - - - - - DUF4105 JFBFHGED_02224 349741.Amuc_1996 9.93e-136 384.0 COG3409@1|root,COG3409@2|Bacteria 2|Bacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - CHAP,DUF1906,PG_binding_1,Peptidase_M15_4 JFBFHGED_02225 349741.Amuc_1995 0.0 956.0 COG3033@1|root,COG3033@2|Bacteria,46X9C@74201|Verrucomicrobia,2IV3F@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Beta-eliminating lyase - - 4.1.99.1 ko:K01667 ko00380,map00380 - R00673 RC00209,RC00355 ko00000,ko00001,ko01000 - - - Beta_elim_lyase JFBFHGED_02226 742740.HMPREF9474_02214 9.25e-68 213.0 COG1573@1|root,COG1573@2|Bacteria,1V1SU@1239|Firmicutes,24E7B@186801|Clostridia 186801|Clostridia L Uracil DNA glycosylase superfamily - - - - - - - - - - - - UDG JFBFHGED_02227 1116472.MGMO_47c00160 3.6e-36 140.0 COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,1RMDQ@1236|Gammaproteobacteria,1XE9V@135618|Methylococcales 135618|Methylococcales KLT Tyrosine-protein kinase, subgroup, catalytic domain - - - - - - - - - - - - Pkinase JFBFHGED_02228 349741.Amuc_1993 1.94e-219 606.0 COG2958@1|root,COG2958@2|Bacteria,46ZH0@74201|Verrucomicrobia,2IU9M@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein conserved in bacteria - - - - - - - - - - - - - JFBFHGED_02229 349741.Amuc_1992 9.35e-203 563.0 COG1277@1|root,COG1277@2|Bacteria,46VKD@74201|Verrucomicrobia,2IUKU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ABC-type transport system involved in multi-copper enzyme maturation permease component - - - - - - - - - - - - ABC2_membrane_2 JFBFHGED_02230 411901.BACCAC_03525 5.33e-124 354.0 COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia,4APB3@815|Bacteroidaceae 976|Bacteroidetes L COG COG2818 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco JFBFHGED_02231 349741.Amuc_1990 4.96e-162 457.0 COG0345@1|root,COG0345@2|Bacteria,46T4K@74201|Verrucomicrobia,2IUB9@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Pyrroline-5-carboxylate reductase dimerisation proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer JFBFHGED_02234 349741.Amuc_1987 3.23e-220 610.0 COG1657@1|root,COG1657@2|Bacteria,46UYQ@74201|Verrucomicrobia,2ITJS@203494|Verrucomicrobiae 203494|Verrucomicrobiae I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - - JFBFHGED_02235 349741.Amuc_1986 2.96e-109 319.0 2AW0Q@1|root,31MVA@2|Bacteria,46X6M@74201|Verrucomicrobia,2IUQT@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02236 349741.Amuc_1985 0.0 1391.0 COG1196@1|root,COG1196@2|Bacteria,46TP5@74201|Verrucomicrobia,2IWNP@203494|Verrucomicrobiae 203494|Verrucomicrobiae D nuclear chromosome segregation - - - - - - - - - - - - - JFBFHGED_02237 349741.Amuc_1984 0.0 1301.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,46XAD@74201|Verrucomicrobia,2IV6P@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Methylmalonyl-CoA mutase - - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - MM_CoA_mutase JFBFHGED_02238 349741.Amuc_1983 0.0 1392.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,46TP8@74201|Verrucomicrobia,2IU9J@203494|Verrucomicrobiae 203494|Verrucomicrobiae I Methylmalonyl-CoA mutase - - 5.4.99.2 ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase JFBFHGED_02240 349741.Amuc_1977 1.6e-193 539.0 COG1092@1|root,COG1092@2|Bacteria,46SYW@74201|Verrucomicrobia,2ITU3@203494|Verrucomicrobiae 203494|Verrucomicrobiae J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM JFBFHGED_02241 349741.Amuc_1976 4.25e-233 644.0 COG0790@1|root,COG0790@2|Bacteria,46ZHX@74201|Verrucomicrobia,2IUWA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - Sel1 JFBFHGED_02242 349741.Amuc_1975 0.0 967.0 COG0166@1|root,COG0166@2|Bacteria,46SUH@74201|Verrucomicrobia,2ITZ9@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Phosphoglucose isomerase pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI JFBFHGED_02244 349741.Amuc_1974 0.0 1757.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,2ITZ4@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N JFBFHGED_02245 338963.Pcar_0670 2.96e-47 160.0 COG0551@1|root,COG0551@2|Bacteria,1RCA8@1224|Proteobacteria,42R20@68525|delta/epsilon subdivisions,2WN67@28221|Deltaproteobacteria,43SKQ@69541|Desulfuromonadales 28221|Deltaproteobacteria L 23S rRNA-intervening sequence protein - - - - - - - - - - - - 23S_rRNA_IVP JFBFHGED_02246 349741.Amuc_1973 1.72e-136 386.0 COG2360@1|root,COG2360@2|Bacteria,46VHR@74201|Verrucomicrobia,2IUHM@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat - 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans JFBFHGED_02247 349741.Amuc_1972 5.64e-232 640.0 COG1194@1|root,COG1194@2|Bacteria,46SR4@74201|Verrucomicrobia,2ITPI@203494|Verrucomicrobiae 203494|Verrucomicrobiae L endonuclease III - - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD JFBFHGED_02248 349741.Amuc_1971 1.39e-205 570.0 COG0169@1|root,COG0169@2|Bacteria,46SVF@74201|Verrucomicrobia,2IU86@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N JFBFHGED_02249 1235802.C823_06156 1.19e-115 335.0 COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,248RZ@186801|Clostridia,25W5Q@186806|Eubacteriaceae 186801|Clostridia S Protein of unknown function (DUF5131) - - - - - - - - - - - - DUF4186,DUF5131 JFBFHGED_02250 349741.Amuc_1970 0.0 2310.0 COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia,2IWJ7@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC JFBFHGED_02252 349741.Amuc_1968 2.49e-168 470.0 COG5522@1|root,COG5522@2|Bacteria,46WTQ@74201|Verrucomicrobia,2IW7Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Integral membrane protein (intg_mem_TP0381) - - - - - - - - - - - - Intg_mem_TP0381 JFBFHGED_02253 349741.Amuc_1967 4.51e-107 310.0 COG3118@1|root,COG3118@2|Bacteria 2|Bacteria O belongs to the thioredoxin family agmK - 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko01000,ko03110 - - - Arylsulfotrans,TPR_8,Thioredoxin JFBFHGED_02257 349741.Amuc_1965 2.11e-273 750.0 COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia,2ITJM@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Amino acid kinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 JFBFHGED_02258 349741.Amuc_1964 1.63e-314 857.0 COG0077@1|root,COG0460@1|root,COG0077@2|Bacteria,COG0460@2|Bacteria,46SIY@74201|Verrucomicrobia,2ITHE@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 JFBFHGED_02260 349741.Amuc_1963 2.06e-102 298.0 COG3610@1|root,COG3610@2|Bacteria,46WV7@74201|Verrucomicrobia 74201|Verrucomicrobia S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 JFBFHGED_02261 349741.Amuc_1962 7.23e-166 466.0 COG2966@1|root,COG2966@2|Bacteria,46W6N@74201|Verrucomicrobia 74201|Verrucomicrobia S Putative threonine/serine exporter - - - - - - - - - - - - ThrE JFBFHGED_02262 349741.Amuc_1961 0.0 2313.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,46TG1@74201|Verrucomicrobia,2ITWA@203494|Verrucomicrobiae 203494|Verrucomicrobiae E B12 binding domain - - 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans JFBFHGED_02264 349741.Amuc_1960 7.6e-123 352.0 COG4733@1|root,COG4733@2|Bacteria,46TXW@74201|Verrucomicrobia,2IWPZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae Q PA14 - - - - - - - - - - - - PA14 JFBFHGED_02268 349741.Amuc_1958 5.11e-75 227.0 arCOG05276@1|root,3195F@2|Bacteria,46W1H@74201|Verrucomicrobia 74201|Verrucomicrobia - - - - - - - - - - - - - - - JFBFHGED_02269 863365.XHC_1854 8.55e-26 109.0 COG2755@1|root,COG2755@2|Bacteria,1RDF0@1224|Proteobacteria,1S4J6@1236|Gammaproteobacteria 1236|Gammaproteobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 JFBFHGED_02270 349741.Amuc_1957 1.53e-305 837.0 COG1102@1|root,COG2364@1|root,COG1102@2|Bacteria,COG2364@2|Bacteria 2|Bacteria F Psort location Cytoplasmic, score mmyX - 5.3.1.12 ko:K01812,ko:K07149,ko:K16139 ko00040,ko01100,map00040,map01100 M00061,M00631 R01482,R01983 RC00376 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.2 - - AAA_28,Cytidylate_kin2,MFS_2 JFBFHGED_02271 349741.Amuc_1956 3.45e-98 287.0 COG2606@1|root,COG2606@2|Bacteria 2|Bacteria S Cys-tRNA(Pro) hydrolase activity ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit JFBFHGED_02272 349741.Amuc_1954 1.58e-150 425.0 COG0518@1|root,COG0518@2|Bacteria,46V9Z@74201|Verrucomicrobia,2IW67@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Glutamine amidotransferase class-I - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase JFBFHGED_02273 349741.Amuc_1953 1.31e-103 300.0 COG3467@1|root,COG3467@2|Bacteria 2|Bacteria T pyridoxamine 5'-phosphate - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 JFBFHGED_02274 349741.Amuc_1952 2.93e-158 445.0 COG5522@1|root,COG5522@2|Bacteria,46WTQ@74201|Verrucomicrobia,2IW7Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Integral membrane protein (intg_mem_TP0381) - - - - - - - - - - - - Intg_mem_TP0381 JFBFHGED_02275 349741.Amuc_1951 1.26e-260 715.0 COG1902@1|root,COG1902@2|Bacteria,46SGZ@74201|Verrucomicrobia,2ITH2@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NADH:flavin oxidoreductase / NADH oxidase family - - - - - - - - - - - - Oxidored_FMN JFBFHGED_02276 349741.Amuc_1950 4.64e-125 358.0 COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia,2IU46@203494|Verrucomicrobiae 203494|Verrucomicrobiae EH Peptidase C26 - - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase JFBFHGED_02277 349741.Amuc_1949 1.43e-212 590.0 COG0147@1|root,COG0147@2|Bacteria 2|Bacteria EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia pabB - 2.6.1.85,4.1.3.27,4.1.3.38 ko:K01665,ko:K03342,ko:K13503,ko:K13950 ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01716,R05553 RC00010,RC01418,RC01843,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4,Anth_synt_I_N,Chorismate_bind JFBFHGED_02278 349741.Amuc_1948 3.45e-119 343.0 COG0115@1|root,COG0115@2|Bacteria 2|Bacteria E branched-chain-amino-acid transaminase activity - - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 JFBFHGED_02279 633697.EubceDRAFT1_2817 0.0 885.0 COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1TQ81@1239|Firmicutes,24BX6@186801|Clostridia,25XTX@186806|Eubacteriaceae 186801|Clostridia S Protein of unknown function DUF262 - - - - - - - - - - - - DUF262 JFBFHGED_02280 349741.Amuc_1947 2.95e-283 774.0 COG2942@1|root,COG2942@2|Bacteria,46UIM@74201|Verrucomicrobia,2ITK6@203494|Verrucomicrobiae 203494|Verrucomicrobiae G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - 5.1.3.8 ko:K01787 ko00520,map00520 - R01207 RC00290 ko00000,ko00001,ko01000 - - - GlcNAc_2-epim JFBFHGED_02281 349741.Amuc_1946 4.95e-217 599.0 COG0329@1|root,COG0329@2|Bacteria,46UHJ@74201|Verrucomicrobia,2IU2T@203494|Verrucomicrobiae 203494|Verrucomicrobiae EM Dihydrodipicolinate synthetase family - - 4.1.3.3 ko:K01639 ko00520,map00520 - R01811 RC00159,RC00600 ko00000,ko00001,ko01000 - - - DHDPS JFBFHGED_02282 1122986.KB908319_gene207 6.09e-17 91.3 COG3325@1|root,COG3325@2|Bacteria,4NGAZ@976|Bacteroidetes,2FNA4@200643|Bacteroidia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 18 family - - 3.2.1.14,3.2.1.4 ko:K01179,ko:K01183 ko00500,ko00520,ko01100,map00500,map00520,map01100 - R01206,R02334,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 - GH18,GH5,GH9 - Glyco_hydro_18 JFBFHGED_02283 264202.CF0727 8.47e-07 62.4 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - - - - - - - - - - Autotransporter,CHU_C,Calx-beta,ChlamPMP_M,Chlam_PMP,DUF11,Haemagg_act JFBFHGED_02285 349741.Amuc_1945 3.61e-315 865.0 2C7EB@1|root,347YC@2|Bacteria,46W4Z@74201|Verrucomicrobia,2IUKP@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02286 349741.Amuc_1944 1.02e-184 515.0 COG2084@1|root,COG2084@2|Bacteria,46U4D@74201|Verrucomicrobia,2IUCN@203494|Verrucomicrobiae 203494|Verrucomicrobiae I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 JFBFHGED_02287 349741.Amuc_1943 0.0 1286.0 COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,2IUR7@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_8 JFBFHGED_02288 349741.Amuc_1942 2.39e-276 758.0 COG2195@1|root,COG2195@2|Bacteria 2|Bacteria E Cleaves the N-terminal amino acid of tripeptides pepT - 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 JFBFHGED_02290 349741.Amuc_1941 0.0 916.0 COG0015@1|root,COG0015@2|Bacteria,46UUE@74201|Verrucomicrobia,2ITG6@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Adenylosuccinate lyase C-terminus - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 JFBFHGED_02291 349741.Amuc_1940 1.15e-98 287.0 COG5465@1|root,COG5465@2|Bacteria 2|Bacteria S Putative bacterial sensory transduction regulator MA20_05485 - - - - - - - - - - - YbjN JFBFHGED_02292 349741.Amuc_1939 1.02e-207 581.0 COG0845@1|root,COG0845@2|Bacteria,46VEA@74201|Verrucomicrobia,2IUBR@203494|Verrucomicrobiae 203494|Verrucomicrobiae M HlyD family secretion protein - - - - - - - - - - - - HlyD_3 JFBFHGED_02293 1454007.JAUG01000029_gene3240 2.07e-173 518.0 COG3345@1|root,COG3345@2|Bacteria,4NMDV@976|Bacteroidetes,1IX7H@117747|Sphingobacteriia 976|Bacteroidetes G alpha-galactosidase - - - - - - - - - - - - Big_2 JFBFHGED_02294 349741.Amuc_1938 0.0 1737.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,46URE@74201|Verrucomicrobia,2ITXE@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Helix-hairpin-helix class 2 (Pol1 family) motifs - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 JFBFHGED_02297 349741.Amuc_1937 2.28e-99 291.0 COG0634@1|root,COG0634@2|Bacteria,46T02@74201|Verrucomicrobia,2IUJK@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Phosphoribosyl transferase domain - - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran JFBFHGED_02299 642492.Clole_1499 2.43e-43 145.0 2DZZV@1|root,32VPC@2|Bacteria,1VE1I@1239|Firmicutes,24KP7@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - Cass2 JFBFHGED_02300 349741.Amuc_1935 1.25e-114 331.0 COG1247@1|root,COG1247@2|Bacteria,46T83@74201|Verrucomicrobia,2IURQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 JFBFHGED_02301 1449050.JNLE01000003_gene1944 5.41e-77 232.0 COG0454@1|root,COG0456@2|Bacteria,1VAAI@1239|Firmicutes,24ID9@186801|Clostridia,36J2R@31979|Clostridiaceae 186801|Clostridia K Acetyltransferase (GNAT) domain - - - ko:K03827 - - - - ko00000,ko01000 - - - Acetyltransf_10 JFBFHGED_02302 349741.Amuc_1925 1.81e-190 533.0 COG4763@1|root,COG4763@2|Bacteria,46X0A@74201|Verrucomicrobia,2IWAP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_02303 1396141.BATP01000040_gene2097 5.71e-163 505.0 COG3119@1|root,COG3119@2|Bacteria,46UIA@74201|Verrucomicrobia,2IVFY@203494|Verrucomicrobiae 203494|Verrucomicrobiae P PA14 domain - - - - - - - - - - - - PA14,Sulfatase JFBFHGED_02304 349741.Amuc_1924 0.0 1255.0 COG3525@1|root,COG3525@2|Bacteria 2|Bacteria G beta-N-acetylhexosaminidase activity - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_02307 349741.Amuc_1923 2.5e-89 263.0 COG5512@1|root,COG5512@2|Bacteria,46WKB@74201|Verrucomicrobia,2IUW6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 JFBFHGED_02308 349741.Amuc_1922 2.5e-47 151.0 COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,2IURJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae C 4Fe-4S single cluster domain of Ferredoxin I - - - - - - - - - - - - Fer4_13 JFBFHGED_02309 349741.Amuc_1921 0.0 1168.0 COG0815@1|root,COG0815@2|Bacteria,46SPW@74201|Verrucomicrobia,2IU1H@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Carbon-nitrogen hydrolase - - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase JFBFHGED_02310 349741.Amuc_1920 3.26e-153 433.0 COG3698@1|root,COG3698@2|Bacteria,46W6D@74201|Verrucomicrobia,2IUTV@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Phosphodiester glycosidase - - - - - - - - - - - - NAGPA JFBFHGED_02311 349741.Amuc_1919 1.77e-190 531.0 COG1208@1|root,COG1208@2|Bacteria,46SJP@74201|Verrucomicrobia,2IU9T@203494|Verrucomicrobiae 203494|Verrucomicrobiae JM Nucleotidyl transferase - - 2.7.7.13 ko:K00966 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase JFBFHGED_02312 349741.Amuc_1918 4.45e-310 845.0 COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,2ITYH@203494|Verrucomicrobiae 203494|Verrucomicrobiae IM Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis fabZ - 3.5.1.108,4.2.1.59 ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 M00060,M00083 R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965 RC00166,RC00300,RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 - - - FabA,LpxC JFBFHGED_02313 349741.Amuc_1917 9.79e-214 592.0 COG0524@1|root,COG0524@2|Bacteria,46U0Y@74201|Verrucomicrobia,2IU19@203494|Verrucomicrobiae 203494|Verrucomicrobiae G pfkB family carbohydrate kinase - - - - - - - - - - - - PfkB JFBFHGED_02314 349741.Amuc_1916 1.72e-66 203.0 COG0239@1|root,COG0239@2|Bacteria 2|Bacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB JFBFHGED_02315 1122990.BAJH01000017_gene2019 3.43e-34 121.0 COG1993@1|root,COG1993@2|Bacteria,4NVRH@976|Bacteroidetes,2FV2T@200643|Bacteroidia 976|Bacteroidetes S Uncharacterized ACR, COG1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 JFBFHGED_02316 349741.Amuc_1911 1.46e-266 731.0 COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia,2IUNH@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Iron-containing alcohol dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - Fe-ADH JFBFHGED_02318 349741.Amuc_1906 5.46e-184 514.0 COG4974@1|root,COG4974@2|Bacteria,46SSD@74201|Verrucomicrobia,2ITH5@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Phage integrase, N-terminal SAM-like domain - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase JFBFHGED_02319 349741.Amuc_1905 1.81e-251 691.0 COG3392@1|root,COG3392@2|Bacteria,46WWM@74201|Verrucomicrobia 74201|Verrucomicrobia H PFAM D12 class N6 adenine-specific DNA methyltransferase - - 2.1.1.72 ko:K07318 - - - - ko00000,ko01000,ko02048 - - - MethyltransfD12 JFBFHGED_02322 349741.Amuc_1903 5.72e-238 654.0 2C4R5@1|root,2Z7JK@2|Bacteria 2|Bacteria S Psort location Cytoplasmic, score BT0173 - - - - - - - - - - - GGGtGRT JFBFHGED_02323 349741.Amuc_1902 6.15e-169 471.0 COG0822@1|root,COG0822@2|Bacteria 2|Bacteria C iron-sulfur transferase activity BT0174 - - ko:K04488 - - - - ko00000 - - - NifU_N JFBFHGED_02324 349741.Amuc_1901 7.14e-185 514.0 COG1408@1|root,COG1408@2|Bacteria 2|Bacteria S Calcineurin-like phosphoesterase lpxG - - ko:K07098 - - - - ko00000 - - - Metallophos JFBFHGED_02326 349741.Amuc_1899 6.52e-88 259.0 COG0369@1|root,COG0369@2|Bacteria 2|Bacteria C hydroxylamine reductase activity cysJ - 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_1,Flavodoxin_1,NAD_binding_1 JFBFHGED_02327 883096.HMPREF9699_00261 3.02e-13 82.0 COG3063@1|root,COG3063@2|Bacteria 2|Bacteria NU photosynthesis - - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - ANAPC5,Glycos_transf_1,HTH_18,TPR_16,TPR_2,TPR_8,Wzy_C JFBFHGED_02329 349741.Amuc_1897 1.79e-245 676.0 COG0082@1|root,COG0082@2|Bacteria,46SEA@74201|Verrucomicrobia,2ITMN@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC - 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt JFBFHGED_02330 349741.Amuc_1896 1.5e-49 158.0 COG0776@1|root,COG0776@2|Bacteria,46T4R@74201|Verrucomicrobia,2IUNA@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding JFBFHGED_02331 349741.Amuc_1895 3.57e-298 814.0 COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia,2ITRZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) - - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase JFBFHGED_02333 349741.Amuc_1894 5.85e-293 802.0 COG0128@1|root,COG0128@2|Bacteria,46SFD@74201|Verrucomicrobia,2ITVM@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase JFBFHGED_02334 349741.Amuc_1893 1.28e-73 221.0 COG0727@1|root,COG0727@2|Bacteria,46W4U@74201|Verrucomicrobia,2IUJ6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Putative zinc- or iron-chelating domain - - - ko:K06940 - - - - ko00000 - - - CxxCxxCC JFBFHGED_02337 435591.BDI_1247 5.02e-35 121.0 COG3153@1|root,COG3153@2|Bacteria,4NU0E@976|Bacteroidetes,2FTTC@200643|Bacteroidia,22YQ4@171551|Porphyromonadaceae 976|Bacteroidetes S Putative zinc ribbon domain - - - - - - - - - - - - Zn_ribbon_2 JFBFHGED_02338 1278073.MYSTI_05589 3.99e-67 238.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CFM@68525|delta/epsilon subdivisions,2X7QN@28221|Deltaproteobacteria,2YZ34@29|Myxococcales 28221|Deltaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA JFBFHGED_02339 349741.Amuc_1728 5.57e-75 233.0 COG0745@1|root,COG0745@2|Bacteria,46UZH@74201|Verrucomicrobia,2IVRM@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C JFBFHGED_02340 1121912.AUHD01000006_gene1335 3.09e-86 281.0 COG2304@1|root,COG2304@2|Bacteria,4NEGD@976|Bacteroidetes,1HY72@117743|Flavobacteriia 976|Bacteroidetes P von Willebrand factor, type A - - - - - - - - - - - - VWA JFBFHGED_02341 215803.DB30_6945 3.53e-58 219.0 COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42QVZ@68525|delta/epsilon subdivisions,2WMVN@28221|Deltaproteobacteria,2YUQR@29|Myxococcales 28221|Deltaproteobacteria S Vault protein inter-alpha-trypsin domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VIT,VWA_3 JFBFHGED_02342 349741.Amuc_1890 3.79e-187 521.0 COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia,2IURU@203494|Verrucomicrobiae 203494|Verrucomicrobiae V Bacitracin resistance protein BacA uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA JFBFHGED_02343 349741.Amuc_1889 9.01e-223 619.0 COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,2ITNJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC JFBFHGED_02344 349741.Amuc_1888 7.87e-311 848.0 COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,46SJ3@74201|Verrucomicrobia,2ITYY@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c JFBFHGED_02345 509191.AEDB02000073_gene1982 6.05e-14 81.6 COG2159@1|root,COG2159@2|Bacteria,1W49D@1239|Firmicutes,254HV@186801|Clostridia 186801|Clostridia S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 JFBFHGED_02346 349741.Amuc_1887 0.0 1379.0 COG3264@1|root,COG3264@2|Bacteria 2|Bacteria M cellular water homeostasis kefA GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K05802,ko:K22051 - - - - ko00000,ko02000 1.A.23.1.1,1.A.23.1.2,1.A.23.1.3 - - DUF3772,MS_channel,MscS_TM,MscS_porin JFBFHGED_02347 349741.Amuc_1886 2.07e-89 262.0 COG0780@1|root,COG0780@2|Bacteria,46SYQ@74201|Verrucomicrobia,2IUI4@203494|Verrucomicrobiae 203494|Verrucomicrobiae S QueF-like protein queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF JFBFHGED_02348 349741.Amuc_1885 2.32e-151 426.0 COG0603@1|root,COG0603@2|Bacteria,46SEU@74201|Verrucomicrobia,2IU6V@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Queuosine biosynthesis protein QueC queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC JFBFHGED_02349 349741.Amuc_1884 2.12e-130 372.0 COG0125@1|root,COG0125@2|Bacteria,46YZ4@74201|Verrucomicrobia,2IUD6@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin JFBFHGED_02350 349741.Amuc_1883 0.0 889.0 COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,2ITW2@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Beta-Casp domain - - - - - - - - - - - - Beta-Casp,Lactamase_B,RMMBL JFBFHGED_02351 180332.JTGN01000005_gene3088 1.49e-70 217.0 COG0454@1|root,COG0456@2|Bacteria,1VJ9N@1239|Firmicutes,24KBX@186801|Clostridia 186801|Clostridia K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 JFBFHGED_02354 349741.Amuc_1882 1.33e-57 179.0 COG3339@1|root,COG3339@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1232) - - - - - - - - - - - - DUF1232 JFBFHGED_02355 349741.Amuc_1881 9.14e-144 407.0 2DDRS@1|root,2ZJ0Y@2|Bacteria 2|Bacteria S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 JFBFHGED_02356 349741.Amuc_1880 4.67e-298 813.0 COG0538@1|root,COG0538@2|Bacteria,46Z6W@74201|Verrucomicrobia,2IVFR@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh JFBFHGED_02357 767817.Desgi_3822 9.56e-77 231.0 COG0346@1|root,COG0346@2|Bacteria,1V6FU@1239|Firmicutes,249UP@186801|Clostridia,266XF@186807|Peptococcaceae 186801|Clostridia E PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily - - - ko:K07032 - - - - ko00000 - - - Glyoxalase JFBFHGED_02360 349741.Amuc_1876 0.0 1158.0 COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,46TWP@74201|Verrucomicrobia,2ITWT@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C JFBFHGED_02361 349741.Amuc_1875 1.28e-100 303.0 COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,2ITX9@203494|Verrucomicrobiae 203494|Verrucomicrobiae P ABC-type Zn2 transport system, periplasmic component surface adhesin - - - - - - - - - - - - - JFBFHGED_02362 349741.Amuc_1875 7.6e-121 356.0 COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,2ITX9@203494|Verrucomicrobiae 203494|Verrucomicrobiae P ABC-type Zn2 transport system, periplasmic component surface adhesin - - - - - - - - - - - - - JFBFHGED_02363 349741.Amuc_1874 2.42e-119 345.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - CopD,Cytochrome_CBB3 JFBFHGED_02365 349741.Amuc_1872 5.15e-305 833.0 COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,2ITK9@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD JFBFHGED_02366 349741.Amuc_1871 5.28e-219 607.0 COG1169@1|root,COG1169@2|Bacteria,46YW2@74201|Verrucomicrobia,2IU6K@203494|Verrucomicrobiae 203494|Verrucomicrobiae HQ chorismate binding enzyme - - 5.4.4.2 ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 M00116 R01717 RC00588 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_bind JFBFHGED_02367 349741.Amuc_1870 0.0 1584.0 COG1501@1|root,COG1501@2|Bacteria,46TKY@74201|Verrucomicrobia,2IU43@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolases family 31 - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Gal_mutarotas_2,Glyco_hydro_31 JFBFHGED_02368 349741.Amuc_1869 3.81e-212 592.0 COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,2IUHH@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JFBFHGED_02369 349741.Amuc_1869 8.97e-85 261.0 COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,2IUHH@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 JFBFHGED_02370 349741.Amuc_1868 2.8e-277 759.0 COG1449@1|root,COG1449@2|Bacteria,46XBE@74201|Verrucomicrobia,2IVAX@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 57 - - 3.2.1.1 ko:K07405 ko00500,ko01100,map00500,map01100 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH57 - Glyco_hydro_57 JFBFHGED_02371 411459.RUMOBE_03980 1.02e-33 119.0 COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,24NEC@186801|Clostridia,3Y0CY@572511|Blautia 186801|Clostridia K helix_turn_helix, Arsenical Resistance Operon Repressor czrA - - - - - - - - - - - HTH_20,HTH_5 JFBFHGED_02373 349741.Amuc_1867 2.48e-124 354.0 COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia,2IUCF@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase JFBFHGED_02374 349741.Amuc_1866 3.64e-84 249.0 COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia,2IUR9@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Biopolymer transport protein ExbD/TolR - - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD JFBFHGED_02375 349741.Amuc_1865 2.08e-127 364.0 COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia,2IUJU@203494|Verrucomicrobiae 203494|Verrucomicrobiae U MotA/TolQ/ExbB proton channel family - - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB JFBFHGED_02376 349741.Amuc_1864 1.44e-248 687.0 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - DUF1983 JFBFHGED_02377 349741.Amuc_1863 2.86e-113 325.0 COG0629@1|root,COG0629@2|Bacteria,46VGA@74201|Verrucomicrobia,2IUK4@203494|Verrucomicrobiae 203494|Verrucomicrobiae L Single-strand binding protein family - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB JFBFHGED_02378 349741.Amuc_1862 1.07e-300 820.0 COG0151@1|root,COG0151@2|Bacteria,46SGJ@74201|Verrucomicrobia,2ITXH@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N JFBFHGED_02379 349741.Amuc_1861 5.19e-128 365.0 COG3738@1|root,COG3738@2|Bacteria,46X3M@74201|Verrucomicrobia,2IUCP@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Domain of unknown function (DUF1287) - - - ko:K09974 - - - - ko00000 - - - DUF1287 JFBFHGED_02380 349741.Amuc_1860 0.0 1031.0 COG2759@1|root,COG2759@2|Bacteria,46SGS@74201|Verrucomicrobia 74201|Verrucomicrobia H Formate--tetrahydrofolate ligase fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS JFBFHGED_02381 349741.Amuc_1859 1.05e-208 578.0 COG1893@1|root,COG1893@2|Bacteria,46SK2@74201|Verrucomicrobia,2IU3H@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Ketopantoate reductase PanE/ApbA C terminal - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C JFBFHGED_02382 349741.Amuc_1858 0.0 1176.0 COG3410@1|root,COG3410@2|Bacteria 2|Bacteria LO Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075 JFBFHGED_02383 349741.Amuc_1857 9.38e-197 546.0 COG0457@1|root,COG0457@2|Bacteria,46VY0@74201|Verrucomicrobia,2IUSH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Tetratricopeptide repeat - - - - - - - - - - - - - JFBFHGED_02384 349741.Amuc_1856 1.14e-175 490.0 COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia,2ITKJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 JFBFHGED_02385 349741.Amuc_1855 0.0 875.0 COG0601@1|root,COG0601@2|Bacteria,46TSV@74201|Verrucomicrobia,2ITNK@203494|Verrucomicrobiae 203494|Verrucomicrobiae EP Binding-protein-dependent transport system inner membrane component - - - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 JFBFHGED_02386 349741.Amuc_1854 0.0 1025.0 COG4239@1|root,COG4239@2|Bacteria,46UMY@74201|Verrucomicrobia,2ITTS@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Binding-protein-dependent transport system inner membrane component - - - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 JFBFHGED_02387 349741.Amuc_1853 0.0 1474.0 COG4166@1|root,COG4166@2|Bacteria,46UFF@74201|Verrucomicrobia,2ITVT@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 JFBFHGED_02388 349741.Amuc_1852 1.28e-229 632.0 COG0444@1|root,COG0444@2|Bacteria,46YTM@74201|Verrucomicrobia,2IU2Y@203494|Verrucomicrobiae 203494|Verrucomicrobiae EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY JFBFHGED_02389 349741.Amuc_1851 1.99e-238 655.0 COG4608@1|root,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,2ITPK@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY JFBFHGED_02390 349741.Amuc_1850 3.44e-262 718.0 COG0787@1|root,COG0787@2|Bacteria,46SM1@74201|Verrucomicrobia,2IU27@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N JFBFHGED_02393 349741.Amuc_1849 6.89e-177 497.0 COG0697@1|root,COG0697@2|Bacteria,46U7M@74201|Verrucomicrobia,2IVXJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae EG EamA-like transporter family - - - - - - - - - - - - EamA JFBFHGED_02394 1506583.JQJY01000005_gene2178 2e-283 806.0 COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia,2NT1D@237|Flavobacterium 976|Bacteroidetes Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 JFBFHGED_02395 349741.Amuc_1847 3.59e-299 818.0 COG0232@1|root,COG0232@2|Bacteria,46UHP@74201|Verrucomicrobia,2ITWR@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Phosphohydrolase-associated domain - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc JFBFHGED_02397 349741.Amuc_1844 2.66e-203 565.0 COG0265@1|root,COG0265@2|Bacteria,46YDU@74201|Verrucomicrobia,2IUZ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 JFBFHGED_02399 349741.Amuc_1842 2.45e-123 353.0 COG1595@1|root,COG1595@2|Bacteria,46WAM@74201|Verrucomicrobia,2IWJD@203494|Verrucomicrobiae 203494|Verrucomicrobiae K ECF sigma factor - - - - - - - - - - - - Sigma70_r2,Sigma70_r4 JFBFHGED_02400 349741.Amuc_1841 2.49e-171 484.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 2.7.1.180,5.3.4.1 ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko01000,ko02000,ko03110 5.A.1.2 - - Thioredoxin JFBFHGED_02401 349741.Amuc_1840 0.0 1180.0 COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae 203494|Verrucomicrobiae H ThiC-associated domain - - 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM JFBFHGED_02402 349741.Amuc_1839 0.0 1028.0 COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,2ITMQ@203494|Verrucomicrobiae 74201|Verrucomicrobia P E1-E2 ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase,YHS JFBFHGED_02403 349741.Amuc_1838 2.97e-59 182.0 COG1937@1|root,COG1937@2|Bacteria 2|Bacteria S negative regulation of transcription, DNA-templated csoR - - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal JFBFHGED_02404 1226322.HMPREF1545_04312 1.19e-60 192.0 COG1246@1|root,COG1246@2|Bacteria,1V4QW@1239|Firmicutes,24GCU@186801|Clostridia,2N8KQ@216572|Oscillospiraceae 186801|Clostridia E Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_9,DUF2441 JFBFHGED_02405 349741.Amuc_1836 1.4e-126 361.0 COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,2IUFS@203494|Verrucomicrobiae 203494|Verrucomicrobiae K ECF sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 JFBFHGED_02406 349741.Amuc_1835 0.0 1285.0 COG4409@1|root,COG4409@2|Bacteria,46XBR@74201|Verrucomicrobia,2IVC8@203494|Verrucomicrobiae 203494|Verrucomicrobiae G N-terminal domain of BNR-repeat neuraminidase - - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2,BNR_assoc_N JFBFHGED_02408 349741.Amuc_1834 5.55e-100 293.0 2ERDI@1|root,2ZSFS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_02409 349741.Amuc_1833 0.0 934.0 COG0738@1|root,COG0738@2|Bacteria,46VVQ@74201|Verrucomicrobia,2IU7A@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 JFBFHGED_02410 349741.Amuc_1833 1.5e-23 98.6 COG0738@1|root,COG0738@2|Bacteria,46VVQ@74201|Verrucomicrobia,2IU7A@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 JFBFHGED_02411 349741.Amuc_1832 0.0 1202.0 COG2407@1|root,COG2407@2|Bacteria,46ZAF@74201|Verrucomicrobia,2ITQK@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Converts the aldose L-fucose into the corresponding ketose L-fuculose fucI - 5.3.1.25,5.3.1.3 ko:K01818 ko00051,ko01120,map00051,map01120 - R03163 RC00434 ko00000,ko00001,ko01000 - - - Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 JFBFHGED_02412 749222.Nitsa_0143 2.92e-29 109.0 2CCSR@1|root,32RWC@2|Bacteria,1N8A2@1224|Proteobacteria,42XX5@68525|delta/epsilon subdivisions,2YS1Q@29547|Epsilonproteobacteria 29547|Epsilonproteobacteria S PFAM S23 ribosomal protein - - - - - - - - - - - - 23S_rRNA_IVP JFBFHGED_02413 349741.Amuc_1830 0.0 877.0 COG1070@1|root,COG1070@2|Bacteria,46S5Z@74201|Verrucomicrobia,2IUPF@203494|Verrucomicrobiae 203494|Verrucomicrobiae G FGGY family of carbohydrate kinases, C-terminal domain - - 2.7.1.51 ko:K00879 ko00051,ko01120,map00051,map01120 - R03241 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N JFBFHGED_02414 349741.Amuc_1829 4.7e-198 548.0 COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,2IVPG@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II JFBFHGED_02416 930169.B5T_00318 4.05e-48 160.0 2C10Z@1|root,32UBU@2|Bacteria,1N4XP@1224|Proteobacteria,1SC1C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S LexA-binding, inner membrane-associated putative hydrolase - - - - - - - - - - - - YdjM JFBFHGED_02417 349741.Amuc_0584 1.13e-84 278.0 COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria 2|Bacteria T pathogenesis - - - - - - - - - - - - Autotransporter,ESPR,Haemagg_act,PATR JFBFHGED_02418 349741.Amuc_1828 0.0 1900.0 COG2982@1|root,COG2982@2|Bacteria,46SSM@74201|Verrucomicrobia,2IUJJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae M AsmA-like C-terminal region - - - - - - - - - - - - AsmA_2 JFBFHGED_02419 349741.Amuc_1827 3.79e-155 436.0 COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia,2IU6M@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Pirin - - - ko:K06911 - - - - ko00000 - - - Pirin JFBFHGED_02421 349741.Amuc_1825 1.28e-167 469.0 COG1189@1|root,COG1189@2|Bacteria,46SM8@74201|Verrucomicrobia,2ITPM@203494|Verrucomicrobiae 203494|Verrucomicrobiae J FtsJ-like methyltransferase - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 JFBFHGED_02422 435590.BVU_2039 1.58e-118 343.0 COG0778@1|root,COG0778@2|Bacteria,4NEA5@976|Bacteroidetes,2FNK5@200643|Bacteroidia,4APSS@815|Bacteroidaceae 976|Bacteroidetes C Nitroreductase family yfkO - - - - - - - - - - - Nitroreductase JFBFHGED_02423 272559.BF9343_3097 1.75e-12 65.1 COG0778@1|root,COG0778@2|Bacteria,4NEA5@976|Bacteroidetes,2FNK5@200643|Bacteroidia,4APSS@815|Bacteroidaceae 976|Bacteroidetes C Nitroreductase family yfkO - - - - - - - - - - - Nitroreductase JFBFHGED_02424 457424.BFAG_03471 1.22e-113 331.0 COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,2FRDK@200643|Bacteroidia,4ASNJ@815|Bacteroidaceae 976|Bacteroidetes S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI JFBFHGED_02426 349741.Amuc_1822 4.48e-170 478.0 COG0363@1|root,COG0363@2|Bacteria,46TGA@74201|Verrucomicrobia,2IU20@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso,PIG-L JFBFHGED_02427 349741.Amuc_1821 1.55e-274 752.0 COG1092@1|root,COG1092@2|Bacteria,46SJ5@74201|Verrucomicrobia,2ITMI@203494|Verrucomicrobiae 203494|Verrucomicrobiae J S-adenosylmethionine-dependent methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM JFBFHGED_02428 349741.Amuc_1820 4.7e-57 177.0 COG1837@1|root,COG1837@2|Bacteria,46X7A@74201|Verrucomicrobia,2IUUH@203494|Verrucomicrobiae 203494|Verrucomicrobiae S KH domain - - - ko:K06960 - - - - ko00000 - - - KH_4 JFBFHGED_02429 349741.Amuc_1819 0.0 1529.0 28I8X@1|root,2Z8BQ@2|Bacteria,46V28@74201|Verrucomicrobia,2IVQE@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02432 349741.Amuc_1818 6.57e-308 840.0 COG1092@1|root,COG1092@2|Bacteria,46UWW@74201|Verrucomicrobia,2ITN4@203494|Verrucomicrobiae 203494|Verrucomicrobiae J RNA cap guanine-N2 methyltransferase - - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM JFBFHGED_02433 349741.Amuc_1817 1.6e-192 537.0 COG1091@1|root,COG1091@2|Bacteria,46T6F@74201|Verrucomicrobia,2IUPB@203494|Verrucomicrobiae 203494|Verrucomicrobiae M RmlD substrate binding domain - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind JFBFHGED_02434 349741.Amuc_1816 8.31e-226 622.0 COG4948@1|root,COG4948@2|Bacteria,46X7I@74201|Verrucomicrobia,2IUF3@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Mandelate Racemase Muconate Lactonizing - - 4.2.1.113 ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04031 RC01053 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C JFBFHGED_02435 349741.Amuc_1815 0.0 1403.0 COG3525@1|root,COG3525@2|Bacteria,46XW1@74201|Verrucomicrobia,2IVFW@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 20, domain 2 - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_02437 349741.Amuc_1813 2.93e-313 855.0 COG0534@1|root,COG0534@2|Bacteria,46VU7@74201|Verrucomicrobia 74201|Verrucomicrobia V Polysaccharide biosynthesis C-terminal domain - - - - - - - - - - - - MatE JFBFHGED_02438 349741.Amuc_1812 0.0 988.0 COG0366@1|root,COG0366@2|Bacteria,46X6K@74201|Verrucomicrobia,2IUQP@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Alpha amylase, catalytic domain - - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase JFBFHGED_02439 349741.Amuc_1811 5.66e-87 257.0 COG2731@1|root,COG2731@2|Bacteria 2|Bacteria G single-species biofilm formation - - - - - - - - - - - - DUF386 JFBFHGED_02442 349741.Amuc_1810 9.65e-105 303.0 COG0789@1|root,COG0789@2|Bacteria 2|Bacteria K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 JFBFHGED_02443 443143.GM18_2389 1.4e-83 265.0 COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,42SSF@68525|delta/epsilon subdivisions,2WPME@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 JFBFHGED_02444 349741.Amuc_1804 6.97e-120 343.0 COG0716@1|root,COG0716@2|Bacteria 2|Bacteria C FMN binding - - - - - - - - - - - - Flavodoxin_4 JFBFHGED_02445 349741.Amuc_1803 5.8e-237 655.0 COG1408@1|root,COG1408@2|Bacteria,46YVR@74201|Verrucomicrobia,2IUUC@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Calcineurin-like phosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos JFBFHGED_02446 349741.Amuc_1801 7.4e-221 612.0 COG1073@1|root,COG1073@2|Bacteria,46WVC@74201|Verrucomicrobia,2IVBE@203494|Verrucomicrobiae 203494|Verrucomicrobiae S X-Pro dipeptidyl-peptidase (S15 family) - - - ko:K06889 - - - - ko00000 - - - Peptidase_S15 JFBFHGED_02447 349741.Amuc_1800 7.67e-191 531.0 COG0656@1|root,COG0656@2|Bacteria,46V1C@74201|Verrucomicrobia,2IUK9@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red JFBFHGED_02448 349741.Amuc_1799 7.5e-218 603.0 COG2768@1|root,COG2768@2|Bacteria 2|Bacteria - - - - 1.2.7.3 ko:K00176,ko:K07138 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 M00009,M00011,M00173,M00620 R01197 RC00004,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - DUF362 JFBFHGED_02449 349741.Amuc_1798 1.04e-273 750.0 COG1168@1|root,COG1168@2|Bacteria,46TPH@74201|Verrucomicrobia,2ITQB@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class I and II - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_02450 349741.Amuc_1797 4.78e-129 375.0 COG5434@1|root,COG5434@2|Bacteria 2|Bacteria M polygalacturonase activity - - - - - - - - - - - - DUF3737 JFBFHGED_02451 1158294.JOMI01000001_gene1886 2.38e-125 369.0 COG0697@1|root,COG0697@2|Bacteria,4NGJR@976|Bacteroidetes,2FPY2@200643|Bacteroidia 976|Bacteroidetes EG EamA-like transporter family - - - - - - - - - - - - EamA JFBFHGED_02452 272559.BF9343_2061 4.16e-154 449.0 COG2311@1|root,COG2311@2|Bacteria,4NG01@976|Bacteroidetes,2FP63@200643|Bacteroidia,4AN9T@815|Bacteroidaceae 976|Bacteroidetes S Protein of unknown function (DUF418) - - - ko:K07148 - - - - ko00000 - - - DUF418 JFBFHGED_02453 556269.ACDQ01000009_gene1992 1.56e-29 111.0 COG4925@1|root,COG4925@2|Bacteria,1N8YU@1224|Proteobacteria,2VU3M@28216|Betaproteobacteria 28216|Betaproteobacteria I sulfurtransferase activity - - - - - - - - - - - - Cyclophil_like JFBFHGED_02454 1297617.JPJD01000021_gene1536 3.08e-82 248.0 COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,24G79@186801|Clostridia,2695P@186813|unclassified Clostridiales 186801|Clostridia S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red JFBFHGED_02455 445970.ALIPUT_00443 5.21e-201 573.0 COG1454@1|root,COG1454@2|Bacteria,4NIU1@976|Bacteroidetes,2FP86@200643|Bacteroidia 976|Bacteroidetes C COG1454 Alcohol dehydrogenase class IV - - - - - - - - - - - - Fe-ADH JFBFHGED_02457 349741.Amuc_1794 1.62e-167 471.0 COG1974@1|root,COG1974@2|Bacteria,46XX7@74201|Verrucomicrobia,2IVZZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae KT Peptidase S24-like - - - - - - - - - - - - Peptidase_S24 JFBFHGED_02459 349741.Amuc_1793 2.36e-253 698.0 COG1835@1|root,COG1835@2|Bacteria 2|Bacteria I transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_02463 349741.Amuc_1791 2.77e-143 408.0 COG0265@1|root,COG0265@2|Bacteria,46XAI@74201|Verrucomicrobia,2IUH0@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Trypsin - - - - - - - - - - - - PDZ_2,Trypsin_2 JFBFHGED_02464 349741.Amuc_1790 5.13e-197 551.0 COG0265@1|root,COG0265@2|Bacteria,46ZI3@74201|Verrucomicrobia,2IUFD@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2 JFBFHGED_02465 349741.Amuc_1789 1.99e-197 547.0 2EV5U@1|root,33NKM@2|Bacteria,46WDA@74201|Verrucomicrobia,2IUTJ@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02466 349741.Amuc_1788 0.0 951.0 COG1262@1|root,COG1262@2|Bacteria,46TPR@74201|Verrucomicrobia,2IUDD@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase JFBFHGED_02467 349741.Amuc_1787 7.08e-246 680.0 COG0457@1|root,COG0457@2|Bacteria,46TAX@74201|Verrucomicrobia,2IUS8@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Tetratricopeptide repeat - - - - - - - - - - - - - JFBFHGED_02469 1123070.KB899250_gene528 9.88e-11 66.2 2FHDV@1|root,34981@2|Bacteria,46W9B@74201|Verrucomicrobia,2IURW@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02471 349741.Amuc_1783 1.27e-56 176.0 COG0721@1|root,COG0721@2|Bacteria,46WBS@74201|Verrucomicrobia,2IURF@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln JFBFHGED_02472 349741.Amuc_1782 5.31e-316 863.0 COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,2ITUD@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase JFBFHGED_02473 349741.Amuc_1781 2.48e-228 629.0 COG0714@1|root,COG0714@2|Bacteria,46S9V@74201|Verrucomicrobia,2ITT6@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 JFBFHGED_02474 349741.Amuc_1780 4.32e-202 560.0 COG1721@1|root,COG1721@2|Bacteria,46TNC@74201|Verrucomicrobia,2IU3V@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 JFBFHGED_02475 349741.Amuc_1779 1.08e-122 352.0 2AX6C@1|root,31P4Y@2|Bacteria,46XSW@74201|Verrucomicrobia,2IWHP@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02476 349741.Amuc_1778 2.02e-223 617.0 COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia,2IU8I@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function (DUF1194) - - - - - - - - - - - - VWA JFBFHGED_02477 349741.Amuc_1777 0.0 1026.0 COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46U4T@74201|Verrucomicrobia,2IWN2@203494|Verrucomicrobiae 203494|Verrucomicrobiae S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA_2 JFBFHGED_02478 349741.Amuc_1776 0.0 1496.0 COG0457@1|root,COG0457@2|Bacteria,46SZM@74201|Verrucomicrobia,2IUFN@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Oxygen tolerance - - - - - - - - - - - - BatD JFBFHGED_02479 349741.Amuc_1775 1.1e-194 540.0 COG0656@1|root,COG0656@2|Bacteria 2|Bacteria S aldo-keto reductase (NADP) activity yeaE - - - - - - - - - - - Aldo_ket_red JFBFHGED_02480 742766.HMPREF9455_00447 3.4e-81 246.0 COG0110@1|root,COG0110@2|Bacteria,4NH27@976|Bacteroidetes,2FQA3@200643|Bacteroidia,22XJT@171551|Porphyromonadaceae 976|Bacteroidetes S Hexapeptide repeat of succinyl-transferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 JFBFHGED_02481 1123288.SOV_1c08590 3.37e-182 515.0 COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes,4H3KY@909932|Negativicutes 909932|Negativicutes S Dienelactone hydrolase family - - - ko:K06889 - - - - ko00000 - - - DLH JFBFHGED_02482 1219065.VPR01S_05_01380 1.91e-109 327.0 COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,1T1VS@1236|Gammaproteobacteria,1Y2JH@135623|Vibrionales 135623|Vibrionales K AraC-type transcriptional regulator N-terminus - - - - - - - - - - - - AraC_N,HTH_18 JFBFHGED_02483 349741.Amuc_2065 1.79e-268 736.0 COG3274@1|root,COG3274@2|Bacteria 2|Bacteria S Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_02484 349741.Amuc_2066 0.0 2240.0 COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia,2ITGA@203494|Verrucomicrobiae 203494|Verrucomicrobiae CE Proline dehydrogenase - - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh JFBFHGED_02486 1123070.KB899248_gene24 1.76e-46 155.0 COG1847@1|root,COG1847@2|Bacteria,46VYD@74201|Verrucomicrobia,2IUMF@203494|Verrucomicrobiae 203494|Verrucomicrobiae S R3H domain - - - - - - - - - - - - R3H JFBFHGED_02488 349741.Amuc_2070 0.0 1394.0 COG0753@1|root,COG0753@2|Bacteria,46TCG@74201|Verrucomicrobia,2IUWP@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Catalase - - 1.11.1.6 ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 M00532 R00009,R00602,R02670 RC00034,RC00767,RC02141,RC02755 ko00000,ko00001,ko00002,ko01000 - - - Catalase,Catalase-rel JFBFHGED_02493 349741.Amuc_2071 0.0 1594.0 COG0755@1|root,COG1333@1|root,COG3159@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,COG3159@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae 203494|Verrucomicrobiae O Cytochrome C assembly protein - - - - - - - - - - - - Cytochrom_C_asm JFBFHGED_02494 349741.Amuc_2072 1.36e-130 371.0 COG1592@1|root,COG1592@2|Bacteria 2|Bacteria C Rubrerythrin rbr - - - - - - - - - - - Rubrerythrin JFBFHGED_02496 349741.Amuc_2076 0.0 1465.0 COG1674@1|root,COG3170@1|root,COG1674@2|Bacteria,COG3170@2|Bacteria,46SCV@74201|Verrucomicrobia,2ITHR@203494|Verrucomicrobiae 203494|Verrucomicrobiae D Ftsk_gamma - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma JFBFHGED_02497 349741.Amuc_2080 1.19e-59 196.0 COG2148@1|root,COG2148@2|Bacteria,46UQE@74201|Verrucomicrobia,2IUN5@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf JFBFHGED_02498 349741.Amuc_2077 6.69e-133 382.0 COG1596@1|root,COG1596@2|Bacteria 2|Bacteria M polysaccharide export - - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB JFBFHGED_02499 349741.Amuc_2078 2.17e-274 784.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46V4D@74201|Verrucomicrobia 74201|Verrucomicrobia DM PFAM lipopolysaccharide biosynthesis protein gumC - - ko:K16554 ko05111,map05111 - - - ko00000,ko00001,ko02000 8.A.3.1 - - AAA_31,CbiA,GNVR,Wzz JFBFHGED_02500 349741.Amuc_2079 1.02e-77 239.0 COG4464@1|root,COG4464@2|Bacteria 2|Bacteria GM protein tyrosine phosphatase activity - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - JFBFHGED_02501 349741.Amuc_2081 4.35e-151 428.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups wbyL - - ko:K13002 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 JFBFHGED_02502 349741.Amuc_2082 1.77e-247 682.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups lsgC - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 JFBFHGED_02503 349741.Amuc_2083 8.06e-153 444.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups lsgC - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 JFBFHGED_02504 349741.Amuc_2083 1.81e-57 199.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups lsgC - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 JFBFHGED_02505 349741.Amuc_2084 1.78e-152 442.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups gtf1 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_A_1,Glycos_transf_1 JFBFHGED_02506 349741.Amuc_2085 3.47e-141 409.0 2E5IX@1|root,330A8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_02507 641526.ADIWIN_0127 2.62e-29 124.0 2B0ME@1|root,31SZ4@2|Bacteria,4NS16@976|Bacteroidetes 976|Bacteroidetes S O-Antigen ligase - - - - - - - - - - - - Wzy_C JFBFHGED_02508 1349822.NSB1T_02755 9.63e-94 292.0 COG0438@1|root,COG0438@2|Bacteria,4NJ0C@976|Bacteroidetes,2FYG4@200643|Bacteroidia 976|Bacteroidetes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 JFBFHGED_02509 349741.Amuc_2089 3.41e-173 494.0 COG0438@1|root,COG0438@2|Bacteria,46VET@74201|Verrucomicrobia,2IUKI@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_4_4,Glycos_transf_1 JFBFHGED_02510 349741.Amuc_2090 5.15e-240 664.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups lsgC - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Glycos_transf_2 JFBFHGED_02511 349741.Amuc_2091 0.0 873.0 2BTJC@1|root,32NRX@2|Bacteria,46XRE@74201|Verrucomicrobia,2IWF2@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02512 349741.Amuc_2092 5.3e-104 303.0 COG0110@1|root,COG0110@2|Bacteria,46VHY@74201|Verrucomicrobia,2IW1D@203494|Verrucomicrobiae 203494|Verrucomicrobiae S maltose O-acetyltransferase activity - - - ko:K03818 - - - - ko00000,ko01000 - - - - JFBFHGED_02513 349741.Amuc_2093 9.46e-199 551.0 COG0463@1|root,COG0463@2|Bacteria,46U7T@74201|Verrucomicrobia 74201|Verrucomicrobia M PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 JFBFHGED_02514 349741.Amuc_2094 6.19e-205 571.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2,PS_pyruv_trans JFBFHGED_02515 411479.BACUNI_04074 4.81e-49 174.0 2EXMV@1|root,33QXP@2|Bacteria,4NZSJ@976|Bacteroidetes,2FMBS@200643|Bacteroidia,4AMEM@815|Bacteroidaceae 976|Bacteroidetes S Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_02516 349741.Amuc_2094 6.6e-42 155.0 COG0463@1|root,COG0463@2|Bacteria 2|Bacteria M Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2,PS_pyruv_trans JFBFHGED_02517 1122971.BAME01000014_gene1675 2.68e-70 240.0 COG2244@1|root,COG2244@2|Bacteria,4NHYC@976|Bacteroidetes,2FQKS@200643|Bacteroidia,22Z93@171551|Porphyromonadaceae 976|Bacteroidetes S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C JFBFHGED_02518 1235802.C823_02943 4.07e-117 382.0 COG1035@1|root,COG1035@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,25WSS@186806|Eubacteriaceae 186801|Clostridia C Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus - - - - - - - - - - - - Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N,PS_pyruv_trans JFBFHGED_02519 349741.Amuc_2143 1.07e-146 423.0 COG4763@1|root,COG4763@2|Bacteria 2|Bacteria S transferase activity, transferring acyl groups other than amino-acyl groups - - - ko:K11941 - - - - ko00000,ko01000 - - - Acyl_transf_3 JFBFHGED_02521 573061.Clocel_3375 4.05e-72 236.0 COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia,36NVS@31979|Clostridiaceae 186801|Clostridia S Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 JFBFHGED_02523 349741.Amuc_2100 2.99e-264 725.0 COG3173@1|root,COG3173@2|Bacteria 2|Bacteria S very-long-chain-acyl-CoA dehydrogenase activity - - - - - - - - - - - - APH,EcKinase,HMG-CoA_red JFBFHGED_02524 349741.Amuc_2101 4.16e-93 272.0 COG4154@1|root,COG4154@2|Bacteria,46XH1@74201|Verrucomicrobia,2IVWI@203494|Verrucomicrobiae 203494|Verrucomicrobiae G RbsD / FucU transport protein family - - 5.1.3.29 ko:K02431 - - R10764 RC00563 ko00000,ko01000 - - - RbsD_FucU JFBFHGED_02525 349741.Amuc_2102 2.13e-188 531.0 COG1168@1|root,COG1168@2|Bacteria,46TPH@74201|Verrucomicrobia,2ITQB@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class I and II - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_02526 349741.Amuc_2102 2.93e-41 145.0 COG1168@1|root,COG1168@2|Bacteria,46TPH@74201|Verrucomicrobia,2ITQB@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class I and II - - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_02528 349741.Amuc_2103 0.0 1075.0 COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,2ITVG@203494|Verrucomicrobiae 203494|Verrucomicrobiae J tRNA synthetases class I (C) catalytic domain - - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g JFBFHGED_02529 349741.Amuc_2104 0.0 971.0 COG1165@1|root,COG1165@2|Bacteria,46URH@74201|Verrucomicrobia,2ITVW@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) menD - 2.2.1.9 ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R08165 RC02186 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_N JFBFHGED_02530 349741.Amuc_2106 1.86e-314 857.0 COG0281@1|root,COG0281@2|Bacteria,46UWJ@74201|Verrucomicrobia,2IWHX@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Malic enzyme, NAD binding domain - - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,malic JFBFHGED_02531 349741.Amuc_2107 0.0 2467.0 COG0265@1|root,COG1657@1|root,COG0265@2|Bacteria,COG1657@2|Bacteria 2|Bacteria I PFAM Prenyltransferase squalene oxidase - - - ko:K06889,ko:K09914 - - - - ko00000 - - - DUF4159,Flg_new,Trypsin_2 JFBFHGED_02532 349741.Amuc_2108 2.16e-214 593.0 COG2273@1|root,COG2273@2|Bacteria 2|Bacteria G xyloglucan:xyloglucosyl transferase activity exsH - 3.2.1.178,3.2.1.18,3.2.1.52 ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 M00079 R00022,R04018,R06004,R11316 RC00028,RC00049,RC00077 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 - GH16,GH20,GH33 - CBM_4_9,Glyco_hydro_16 JFBFHGED_02533 349741.Amuc_2109 1.42e-229 635.0 COG1472@1|root,COG1472@2|Bacteria,46S5G@74201|Verrucomicrobia,2ITMC@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 3 N terminal domain - - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - Glyco_hydro_3 JFBFHGED_02534 349741.Amuc_2110 2.54e-125 357.0 COG0461@1|root,COG0461@2|Bacteria,46YZ3@74201|Verrucomicrobia,2IU4N@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran JFBFHGED_02535 349741.Amuc_2111 2.4e-145 410.0 COG1376@1|root,COG1376@2|Bacteria,46VEG@74201|Verrucomicrobia,2IUCV@203494|Verrucomicrobiae 203494|Verrucomicrobiae S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD JFBFHGED_02536 349741.Amuc_2112 0.0 1689.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity yidC - - ko:K03217,ko:K06872 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,DUF4124,PDZ_2,Peptidase_C11,SLH,TPM_phosphatase,TPR_11,Trypsin_2,YidC_periplas JFBFHGED_02537 349741.Amuc_2113 4.31e-257 706.0 COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,2ITVN@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM JFBFHGED_02538 240016.ABIZ01000001_gene2350 3.55e-31 114.0 COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae 203494|Verrucomicrobiae S RNA recognition motif - - - - - - - - - - - - RRM_1 JFBFHGED_02540 349741.Amuc_2115 1.71e-301 823.0 COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,2ITV1@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Seryl-tRNA synthetase N-terminal domain - - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b JFBFHGED_02542 1000565.METUNv1_01745 9.72e-08 61.6 2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria,2W5J1@28216|Betaproteobacteria 28216|Betaproteobacteria S Putative phage abortive infection protein - - - - - - - - - - - - putAbiC JFBFHGED_02543 349741.Amuc_2116 4.37e-269 736.0 COG1063@1|root,COG1063@2|Bacteria,46USX@74201|Verrucomicrobia,2IWQ1@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N JFBFHGED_02545 349741.Amuc_2118 1.86e-211 583.0 COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase JFBFHGED_02546 349741.Amuc_2119 2.03e-226 625.0 COG0714@1|root,COG0714@2|Bacteria,46TCY@74201|Verrucomicrobia,2ITSU@203494|Verrucomicrobiae 203494|Verrucomicrobiae S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 JFBFHGED_02547 349741.Amuc_2120 5.04e-203 563.0 COG1721@1|root,COG1721@2|Bacteria,46UUS@74201|Verrucomicrobia,2ITRG@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 JFBFHGED_02549 349741.Amuc_2121 1.58e-125 358.0 COG0193@1|root,COG0193@2|Bacteria,46T09@74201|Verrucomicrobia,2IUCW@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Peptidyl-tRNA hydrolase - - 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro JFBFHGED_02550 349741.Amuc_2122 0.0 1592.0 COG0744@1|root,COG0744@2|Bacteria,46TMG@74201|Verrucomicrobia,2ITVY@203494|Verrucomicrobiae 203494|Verrucomicrobiae M Transglycosylase - - - - - - - - - - - - Transgly,Transpeptidase JFBFHGED_02551 349741.Amuc_2123 9.4e-240 674.0 COG3170@1|root,COG3170@2|Bacteria 2|Bacteria NU translation initiation factor activity - - 3.4.24.3 ko:K01387 - - - - ko00000,ko01000,ko01002,ko02042 - - - DEAD,Helicase_C,PKD,PPC,Peptidase_M9,Peptidase_M9_N JFBFHGED_02552 349741.Amuc_2124 0.0 904.0 COG1057@1|root,COG1057@2|Bacteria,46S7M@74201|Verrucomicrobia,2ITSC@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - - - - - - - - - - - JFBFHGED_02553 349741.Amuc_2125 3.94e-310 844.0 COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,2ITUE@203494|Verrucomicrobiae 203494|Verrucomicrobiae F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt JFBFHGED_02554 349741.Amuc_2127 0.0 942.0 COG3659@1|root,COG3659@2|Bacteria 2|Bacteria M wide pore channel activity - - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB JFBFHGED_02555 349741.Amuc_2128 3.54e-291 795.0 COG1740@1|root,COG1740@2|Bacteria,46UW4@74201|Verrucomicrobia 74201|Verrucomicrobia C NiFe/NiFeSe hydrogenase small subunit C-terminal - - 1.12.99.6 ko:K06282 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFe_hyd_SSU_C,Oxidored_q6 JFBFHGED_02556 349741.Amuc_2129 0.0 1197.0 COG0374@1|root,COG0374@2|Bacteria,46UEU@74201|Verrucomicrobia 74201|Verrucomicrobia C Nickel-dependent hydrogenase - - 1.12.99.6 ko:K06281 ko00633,ko01120,map00633,map01120 - R08034 RC00250 ko00000,ko00001,ko01000 - - - NiFeSe_Hases JFBFHGED_02557 349741.Amuc_2130 1.97e-275 754.0 COG1969@1|root,COG1969@2|Bacteria,46WHN@74201|Verrucomicrobia 74201|Verrucomicrobia C Prokaryotic cytochrome b561 hyaC - - ko:K03620 ko02020,map02020 - - - ko00000,ko00001 - - - Ni_hydr_CYTB JFBFHGED_02558 349741.Amuc_2131 6.26e-113 325.0 COG0680@1|root,COG0680@2|Bacteria,46WHX@74201|Verrucomicrobia 74201|Verrucomicrobia C Hydrogenase maturation protease - - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI JFBFHGED_02559 349741.Amuc_2132 4.57e-71 214.0 COG0375@1|root,COG0375@2|Bacteria,46WGA@74201|Verrucomicrobia 74201|Verrucomicrobia C Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - ko:K04651 - - - - ko00000,ko03110 - - - HypA JFBFHGED_02561 349741.Amuc_2134 1.74e-64 199.0 COG3296@1|root,COG3296@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4870) - - - ko:K09940 - - - - ko00000 - - - DUF4870 JFBFHGED_02562 349741.Amuc_2135 5.25e-150 424.0 COG0791@1|root,COG0791@2|Bacteria,46VPQ@74201|Verrucomicrobia,2IUIV@203494|Verrucomicrobiae 203494|Verrucomicrobiae M NLP P60 protein - - - - - - - - - - - - - JFBFHGED_02563 349741.Amuc_2136 0.0 1343.0 COG3525@1|root,COG3525@2|Bacteria,46XE0@74201|Verrucomicrobia,2IVMG@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolase family 20, domain 2 - - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_02564 349741.Amuc_2137 3.27e-145 410.0 COG0778@1|root,COG0778@2|Bacteria,46V9P@74201|Verrucomicrobia,2IU8H@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Nitroreductase family - - 1.5.1.34 ko:K10679 ko00633,ko01120,map00633,map01120 - R08014,R08017,R08042 RC00250 ko00000,ko00001,ko01000 - - - Nitroreductase JFBFHGED_02565 349741.Amuc_2138 3.77e-248 682.0 COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Aminotransferase class I and II - - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 JFBFHGED_02566 1158602.I590_03676 1.81e-52 174.0 COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HH5X@91061|Bacilli,4B3D8@81852|Enterococcaceae 91061|Bacilli S GrpB protein - - - - - - - - - - - - GrpB JFBFHGED_02570 349741.Amuc_2142 6.97e-235 661.0 COG0342@1|root,COG0342@2|Bacteria 2|Bacteria U P-P-bond-hydrolysis-driven protein transmembrane transporter activity secD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG JFBFHGED_02571 349741.Amuc_2144 0.0 1100.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,46UJW@74201|Verrucomicrobia,2IU09@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Catalyzes the reversible hydration of fumarate to (S)- malate - - 4.2.1.2 ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - Fumerase,Fumerase_C JFBFHGED_02573 349741.Amuc_2146 1.93e-101 294.0 COG0720@1|root,COG0720@2|Bacteria,46VC9@74201|Verrucomicrobia,2IVQQ@203494|Verrucomicrobiae 203494|Verrucomicrobiae H 6-pyruvoyl tetrahydropterin synthase - - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS JFBFHGED_02575 349741.Amuc_2148 0.0 1025.0 COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae 2|Bacteria G Glycoside hydrolase, family 20, catalytic core - - 3.2.1.52 ko:K01207,ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142 M00079,M00628 R00022,R05963,R06004,R07809,R07810,R10831,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b JFBFHGED_02576 349741.Amuc_2149 5.54e-293 806.0 COG0541@1|root,COG0541@2|Bacteria,46SIU@74201|Verrucomicrobia,2ITP6@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB JFBFHGED_02577 349741.Amuc_2150 1.94e-217 600.0 COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,2ITV3@203494|Verrucomicrobiae 203494|Verrucomicrobiae H Quinolinate synthetase A protein - - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA JFBFHGED_02578 349741.Amuc_2151 9.29e-233 641.0 COG1565@1|root,COG1565@2|Bacteria,46YUZ@74201|Verrucomicrobia,2IU7W@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 JFBFHGED_02581 349741.Amuc_2157 2.18e-137 388.0 COG0377@1|root,COG0377@2|Bacteria,46SMM@74201|Verrucomicrobia,2ITJ6@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 JFBFHGED_02582 349741.Amuc_2158 5.56e-136 385.0 COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae 203494|Verrucomicrobiae C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC - 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa JFBFHGED_02583 349741.Amuc_2159 2.86e-147 419.0 2CXV0@1|root,32T2Q@2|Bacteria,46XHA@74201|Verrucomicrobia,2IVX5@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - JFBFHGED_02584 349741.Amuc_2160 1.04e-69 210.0 COG0571@1|root,COG0571@2|Bacteria,46WCW@74201|Verrucomicrobia,2IUR4@203494|Verrucomicrobiae 203494|Verrucomicrobiae K ribonuclease III activity - - - - - - - - - - - - - JFBFHGED_02586 349741.Amuc_2161 5.73e-124 362.0 COG0318@1|root,COG0318@2|Bacteria,46XUP@74201|Verrucomicrobia,2IUC3@203494|Verrucomicrobiae 203494|Verrucomicrobiae IQ AMP-binding enzyme - - 6.2.1.26 ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R04030 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - AMP-binding JFBFHGED_02587 349741.Amuc_2163 0.0 1506.0 COG0790@1|root,COG0790@2|Bacteria 2|Bacteria S beta-lactamase activity - - - ko:K07126,ko:K13582 ko04112,map04112 - - - ko00000,ko00001 - - - MORN_2,Peptidase_C14,Pkinase,Sel1 JFBFHGED_02588 349741.Amuc_2164 0.0 1460.0 COG3325@1|root,COG3325@2|Bacteria,46X1V@74201|Verrucomicrobia,2IUY1@203494|Verrucomicrobiae 203494|Verrucomicrobiae G Glycosyl hydrolases family 18 - - - - - - - - - - - - Glyco_hydro_18 JFBFHGED_02590 349741.Amuc_2166 9.45e-317 862.0 COG0673@1|root,COG0673@2|Bacteria,46W0X@74201|Verrucomicrobia 74201|Verrucomicrobia S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C JFBFHGED_02591 349741.Amuc_2167 0.0 1379.0 COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,2ITQT@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Peptidase family M3 - - 3.4.24.70 ko:K01414 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 JFBFHGED_02592 1504823.CCMM01000013_gene2627 1.09e-54 179.0 COG0110@1|root,COG0110@2|Bacteria 2|Bacteria S O-acyltransferase activity - - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2 JFBFHGED_02594 349741.Amuc_2169 0.0 1157.0 COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia,2ITX2@203494|Verrucomicrobiae 203494|Verrucomicrobiae J Arginyl tRNA synthetase N terminal dom argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d JFBFHGED_02595 517417.Cpar_0456 1.42e-43 148.0 COG0551@1|root,COG0551@2|Bacteria,1FF54@1090|Chlorobi 1090|Chlorobi L 23S rRNA-intervening sequence protein - - - - - - - - - - - - - JFBFHGED_02598 349741.Amuc_2171 1.34e-193 538.0 COG1594@1|root,COG1594@2|Bacteria,46XN4@74201|Verrucomicrobia,2IW8B@203494|Verrucomicrobiae 203494|Verrucomicrobiae K Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - - - - - - - - - - - - JFBFHGED_02599 349741.Amuc_2172 4.56e-110 317.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase paiA - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 JFBFHGED_02600 349741.Amuc_2173 2.57e-189 531.0 COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae 203494|Verrucomicrobiae CO Redoxin - - - - - - - - - - - - AhpC-TSA JFBFHGED_02601 349741.Amuc_2174 4.15e-71 215.0 COG3070@1|root,COG3070@2|Bacteria 2|Bacteria K positive regulation of type IV pilus biogenesis - - - ko:K07343 - - - - ko00000 - - - TfoX_N JFBFHGED_02602 411464.DESPIG_01756 1.58e-87 271.0 COG4822@1|root,COG4822@2|Bacteria,1P36Y@1224|Proteobacteria,42P9C@68525|delta/epsilon subdivisions,2WK8C@28221|Deltaproteobacteria,2M9VK@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the insertion of Co(2 ) into sirohydrochlorin cbiKp GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016852,GO:0020037,GO:0022607,GO:0042597,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050897,GO:0051259,GO:0051262,GO:0051266,GO:0065003,GO:0071840,GO:0097159,GO:1901363 4.99.1.3 ko:K02190 ko00860,ko01100,map00860,map01100 - R05807 RC01012 ko00000,ko00001,ko01000 - - - CbiK JFBFHGED_02603 1408428.JNJP01000002_gene3732 5.65e-86 261.0 COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,42MGC@68525|delta/epsilon subdivisions,2WM51@28221|Deltaproteobacteria,2MA4W@213115|Desulfovibrionales 28221|Deltaproteobacteria H PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase cbiL - 2.1.1.130,2.1.1.151 ko:K03394 ko00860,ko01100,map00860,map01100 - R03948,R05808 RC00003,RC01035,RC01662 ko00000,ko00001,ko01000 - - iAF987.Gmet_0482 TP_methylase JFBFHGED_02604 563192.HMPREF0179_00028 1.1e-112 343.0 COG3366@1|root,COG3366@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - JFBFHGED_02605 411464.DESPIG_00351 2.85e-99 294.0 COG2082@1|root,COG2082@2|Bacteria,1MX1E@1224|Proteobacteria,42RIY@68525|delta/epsilon subdivisions,2WN0J@28221|Deltaproteobacteria,2MB2Q@213115|Desulfovibrionales 28221|Deltaproteobacteria H PFAM Precorrin-8X methylmutase CbiC CobH cbiC - 5.4.99.60,5.4.99.61 ko:K06042 ko00860,ko01100,map00860,map01100 - R05177,R05814 RC01292,RC01980 ko00000,ko00001,ko01000 - - - CbiC JFBFHGED_02606 563192.HMPREF0179_00026 4.7e-125 374.0 COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,42N2R@68525|delta/epsilon subdivisions,2WJF4@28221|Deltaproteobacteria,2M7Y2@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A cbiD - 2.1.1.195 ko:K02188 ko00860,ko01100,map00860,map01100 - R07773 RC00003,RC02051 ko00000,ko00001,ko01000 - - - CbiD JFBFHGED_02607 1408428.JNJP01000041_gene2774 8.32e-115 349.0 COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,42MEZ@68525|delta/epsilon subdivisions,2WIUW@28221|Deltaproteobacteria,2M8JD@213115|Desulfovibrionales 28221|Deltaproteobacteria H Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit cbiET - 2.1.1.132 ko:K00595 ko00860,ko01100,map00860,map01100 - R05149 RC00003,RC01279 ko00000,ko00001,ko01000 - - - Cons_hypoth95,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase JFBFHGED_02608 1408428.JNJP01000110_gene1596 0.0 939.0 COG1010@1|root,COG2073@1|root,COG2875@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,42P88@68525|delta/epsilon subdivisions,2WMR1@28221|Deltaproteobacteria,2M959@213115|Desulfovibrionales 28221|Deltaproteobacteria H PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase cbiF - 2.1.1.133,2.1.1.271 ko:K05936 ko00860,ko01100,map00860,map01100 - R05181,R05810 RC00003,RC01294,RC02049 ko00000,ko00001,ko01000 - - - CbiG_C,CbiG_N,TP_methylase JFBFHGED_02609 563192.HMPREF0179_05227 2.9e-222 640.0 COG1797@1|root,COG3896@1|root,COG1797@2|Bacteria,COG3896@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2M8QM@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source cbiA - 6.3.5.11,6.3.5.9 ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 - R05224,R05815 RC00010,RC01301 ko00000,ko00001,ko01000 - - iAF987.Gmet_0470 CPT,CbiA,GATase_3 JFBFHGED_02610 1232683.ADIMK_0833 1.68e-40 142.0 COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,4642W@72275|Alteromonadaceae 1236|Gammaproteobacteria H Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids cobO - 2.5.1.17 ko:K19221 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Co_AT_N,CobA_CobO_BtuR JFBFHGED_02612 877421.AUJT01000002_gene1156 1.83e-33 139.0 28IN0@1|root,2Z8NG@2|Bacteria,1VKBU@1239|Firmicutes,24WSS@186801|Clostridia,27J39@186928|unclassified Lachnospiraceae 186801|Clostridia S Glycosyltransferase family 10 (fucosyltransferase) C-term - - - - - - - - - - - - Glyco_transf_10 JFBFHGED_02614 8010.XP_010880597.1 1.15e-08 67.0 KOG2619@1|root,KOG2619@2759|Eukaryota,39RK4@33154|Opisthokonta,3BNWS@33208|Metazoa,3D5HG@33213|Bilateria,48CJ9@7711|Chordata,49AP5@7742|Vertebrata,49TX9@7898|Actinopterygii 33208|Metazoa G Fucosyltransferase 9 (alpha (1,3) fucosyltransferase) fut9b - 2.4.1.152 ko:K03663 ko00515,ko00601,ko00603,ko01100,map00515,map00601,map00603,map01100 - R05904,R06025,R06038,R06039,R06076,R06095,R06221,R06222,R06224,R06227,R06230 - ko00000,ko00001,ko01000,ko01003 - GT10 - Glyco_tran_10_N,Glyco_transf_10 JFBFHGED_02615 873517.HMPREF1977_1679 2.4e-52 199.0 arCOG09486@1|root,2ZC3Y@2|Bacteria,4NNUF@976|Bacteroidetes,1I367@117743|Flavobacteriia,1ET1N@1016|Capnocytophaga 976|Bacteroidetes H Glycosyl transferase family 11 - - - - - - - - - - - - Glyco_transf_11 JFBFHGED_02616 349741.Amuc_1142 2.88e-73 256.0 COG3774@1|root,COG3774@2|Bacteria,46W4E@74201|Verrucomicrobia 74201|Verrucomicrobia M pathogenesis - - - - - - - - - - - - Gly_transf_sug JFBFHGED_02617 349741.Amuc_1140 2.64e-192 540.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K16703 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 JFBFHGED_02619 349741.Amuc_0506 3.6e-26 107.0 COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,2IU0R@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N JFBFHGED_02620 349741.Amuc_1143 1.16e-89 302.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_02621 349741.Amuc_1143 3.1e-40 150.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_02622 349741.Amuc_1143 3.52e-50 189.0 COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae 203494|Verrucomicrobiae M PFAM YD repeat-containing protein - - - - - - - - - - - - Endonuclea_NS_2,RHS_repeat JFBFHGED_02624 1286632.P278_19980 0.000833 45.4 COG0666@1|root,COG0666@2|Bacteria,4NSDC@976|Bacteroidetes,1I46H@117743|Flavobacteriia 976|Bacteroidetes S Ankyrin repeat - - - - - - - - - - - - Ank_2,Ank_3,Ank_4,Ank_5 JFBFHGED_02625 1449063.JMLS01000020_gene5285 2.55e-23 104.0 COG1262@1|root,COG1262@2|Bacteria,1V2AE@1239|Firmicutes,4HFRF@91061|Bacilli,26TF9@186822|Paenibacillaceae 1239|Firmicutes S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase JFBFHGED_02626 644282.Deba_1397 6.1e-30 119.0 COG1247@1|root,COG2518@1|root,COG1247@2|Bacteria,COG2518@2|Bacteria,1RDNE@1224|Proteobacteria,42TWQ@68525|delta/epsilon subdivisions,2WR2E@28221|Deltaproteobacteria 28221|Deltaproteobacteria M PFAM GCN5-related N-acetyltransferase - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_4 JFBFHGED_02627 349741.Amuc_2176 0.0 3544.0 COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia,2ITHY@203494|Verrucomicrobiae 203494|Verrucomicrobiae L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - - JFBFHGED_02630 349741.Amuc_2177 0.0 2075.0 COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,2ITJP@203494|Verrucomicrobiae 203494|Verrucomicrobiae U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW JFBFHGED_02631 349741.Amuc_2178 1.31e-237 655.0 COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,46SH2@74201|Verrucomicrobia,2IU99@203494|Verrucomicrobiae 203494|Verrucomicrobiae E Acetyltransferase (GNAT) family - - 2.3.1.1 ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,Acetyltransf_1 JFBFHGED_02632 7176.CPIJ014718-PA 1.09e-28 122.0 COG4826@1|root,KOG2392@2759|Eukaryota,38VR6@33154|Opisthokonta,3BBFJ@33208|Metazoa,3CT79@33213|Bilateria,422CB@6656|Arthropoda,3SR0J@50557|Insecta,44YMX@7147|Diptera,45FCD@7148|Nematocera 33208|Metazoa V Belongs to the serpin family SERPINI1 GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0004869,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0007275,GO:0007399,GO:0007417,GO:0007422,GO:0008150,GO:0009892,GO:0009987,GO:0010466,GO:0010468,GO:0010605,GO:0010629,GO:0010720,GO:0010817,GO:0010951,GO:0010955,GO:0010975,GO:0010976,GO:0012505,GO:0019222,GO:0022008,GO:0030141,GO:0030154,GO:0030155,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0031344,GO:0031346,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032350,GO:0032351,GO:0032501,GO:0032502,GO:0034248,GO:0034249,GO:0034774,GO:0036477,GO:0043025,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044297,GO:0044421,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045861,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051960,GO:0051962,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060284,GO:0060568,GO:0060570,GO:0061134,GO:0061135,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070613,GO:0080090,GO:0097458,GO:0097708,GO:0098772,GO:0099503,GO:0120035,GO:1903317,GO:1903318,GO:2000026 - ko:K13963 ko05146,map05146 - - - ko00000,ko00001 - - - Serpin JFBFHGED_02633 65393.PCC7424_3210 8.1e-87 270.0 COG1715@1|root,COG1715@2|Bacteria 2|Bacteria V Restriction endonuclease - - - - - - - - - - - - DUF3644,Mrr_cat JFBFHGED_02635 349741.Amuc_0001 2.41e-110 319.0 COG0494@1|root,COG0494@2|Bacteria 2|Bacteria L nUDIX hydrolase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX ## 1962 queries scanned ## Total time (seconds): 247.64773154258728 ## Rate: 7.92 q/s