LOCUS       c00079_gnlPro..        16490 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IAFJHKBB_190.
ACCESSION   c00079_gnlPro..
VERSION     c00079_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 13:11:18
            Original ID  :: gnl|Prokka|IAFJHKBB_190
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3695
            Orig. end    :: 20185
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16490
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13695:16398]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12703
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..16490
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16490
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             1921..2466
                     /locus_tag="ctg79_6"
                     /transl_table=11
                     /translation="MEVFLLMAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIAT
                     HELAEYAKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEY
                     GSNSLEMHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKG
                     REKLPDVDIYSLVQYHGA"
     CDS             complement(2610..3539)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_7"
                     /sec_met_domain="PALP (E-value: 1e-68, bitscore: 222.5,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPNDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEKLVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(3555..4349)
                     /locus_tag="ctg79_8"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKSEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             complement(4477..5007)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_9"
                     /sec_met_domain="PLDc_2 (E-value: 3.9e-27, bitscore: 85.4,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LFPQDLIINITASDEAEGIIAGAKKYIYIQTPYLIPEESILETLI
                     IAANSGIDVRIMVPCMPDHPFVYPATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNI
                     SSVGSANQDFRSYTLNFEVNSFNYNPALTQELKKIFEKDLDKCTLLTNDYFAQQSSWLK
                     FKQYFSRLLSPIF"
     CDS             complement(4958..5704)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_PL_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_10"
                     /sec_met_domain="PLDc_2 (E-value: 1.6e-17, bitscore: 54.3,
                     seeds: 83, tool: rule-based-clusters)"
                     /sec_met_domain="PLDc_PL_1 (E-value: 3.4e-07, bitscore:
                     21.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKEHDLLPEKERLPRVKMLSELNLNNDDAILTFDNQVKVFISGP
                     ELFDQMITDIKNAKKSVSLEFYTFYSNQLGHRVLKALEEAAANGAKVRVIYDTSGSRGT
                     KPSFFDHLRELGGEAQPFISTSKKHWFTTPRLNYHLHRKLVIIDHHIGYIGGFNIGDQY
                     VNKLPKFGLWRDTHLRVIGQSPILMEVRFAMDWNTSIRRTNLPKFELKELKPFTVNRKD
                     INDNKNVAMQIVSSGPNNQHYGIRRG"
     CDS             complement(5719..5964)
                     /locus_tag="ctg79_11"
                     /transl_table=11
                     /translation="MILTWDIIRRTIEVLWIINIAFAVWTVFRSRRSVVATWAWMLVLT
                     VLPGIGFILYLFFGRQLSHDEIFAIQEEQKRYKDII"
     CDS             6139..6603
                     /locus_tag="ctg79_12"
                     /transl_table=11
                     /translation="MLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRNATVYNRHGVKV
                     GHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVNRIKKHSFVYDE
                     NGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVTNY"
     CDS             complement(6672..8945)
                     /locus_tag="ctg79_13"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSNLSDLPDKDVLALAGSATDKRNTGII
                     DIAIDEYLKENNIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYFFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             9074..9928
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     72.5; E-value: 6.7e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg79_14"
                     /sec_met_domain="LysR_substrate (E-value: 8.4e-29,
                     bitscore: 91.0, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.6e-23, bitscore: 72.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAKEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTELRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKYSNWITHLQLVRRKDQKVTPLMKRIIDS
                     LSR"
     CDS             10001..10186
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_15"
                     /sec_met_domain="Amidinotransf (E-value: 1.9e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             10318..10728
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_16"
                     /sec_met_domain="Amidinotransf (E-value: 7.8e-28, bitscore:
                     88.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEMQNATPSLADLAEDPDYPFYL
                     DPMPNVYFTRDQQAAIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWRDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             10949..11230
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_17"
                     /sec_met_domain="Amidinotransf (E-value: 5.4e-31, bitscore:
                     98.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LIKVLKNYLHLSEIDLIPTGGGDAIAAPREQWNDGSNTLAIAPGE
                     VVTYDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRCMSCPLVREDL"
     CDS             11478..12278
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_18"
                     /sec_met_domain="OTCace (E-value: 1.7e-49, bitscore: 158.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 2.3e-24, bitscore:
                     76.8, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFVHLKVLTLTYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHDCTTKVGKEIYEKYGLSEVEV
                     TDEVFNSQYAWQFTEAENRLHSIKAIMAATLGNLFIPSVDEGSK"
     CDS             12281..12703
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg79_19"
                     /sec_met_domain="AA_kinase (E-value: 8e-13, bitscore: 39.1,
                     seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVALGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKPIGPFYTFNEMQR"
     CDS             13230..13766
                     /locus_tag="ctg79_20"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNKGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             13932..15053
                     /locus_tag="ctg79_21"
                     /transl_table=11
                     /translation="LIEYAFLKDSDLTTDSNFMPRYDHSDGYGYFDQEKLTSYMMVNKF
                     KAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQKIPVANLAPFSEKFYR
                     HYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNGVIQLYERQLHTDDER
                     NTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNCFMADELYSITPQGLL
                     SILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYMMSRIIDFQKVLACMR
                     PLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVDFSGPITTWTQILLGR
                     LTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             15069..15230
                     /locus_tag="ctg79_22"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             15233..15838
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg79_23"
                     /sec_met_domain="LysR_substrate (E-value: 9.4e-19,
                     bitscore: 58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLAKKVY"
     CDS             15983..16489
                     /locus_tag="ctg79_24"
                     /transl_table=11
                     /translation="MDSLHSTMNQHIKGKHLSFEERVIIQLRLKDGYSLRAIARELNCS
                     PSTISYEVKRGTVELYHGKVKRYKATQGHDAYQAHRKNCGRKSDFLRKTQFMRYVHKHF
                     FKDGWSLDVCSNRATAVGAFSSRDVVCTKTLYNYVDQGLLDIHNYDLPEKLKRNTKLHR
                     IRKNKK"
ORIGIN
        1 agttgaatac gctaaagaac atggcgttga tactattatt acggatcacc atacttttca
       61 agaaaataag ccagatgctt atgcaattgt tcactgtaat tatcctggtc aagaatatcc
      121 ttttgatgat tattgtggtg caggtgtagc ttatacaatt tgtcgtgagc ttatgcagga
      181 tcctgtacca gaattgctag atttagcaat gatcggtact attggtgaca tggttaaagt
      241 tactggtgaa ggccatatta ttgtaaaacg tgggttagat gttcttaatc aaaccgaacg
      301 accgggctta agagcgctta tcaaaaatgc cggtttaacg ctagaaacga ttaatgagac
      361 agatgtaggc tttaatattg ctcctagact taatgctgtt ggacgtttgg ctaatgctaa
      421 tctggcagta gagcttttgc ttagtgatga tgatcttgag gcacagaaga tcgcagatca
      481 gattgaagac ttaaataata agcgtaaaga gctaactact gaggtttacg atcgctgcat
      541 ggaattagtt cgtgaaaata gttggcaaaa gcaaaatact ttagttttat atgatcctga
      601 ttttcatgaa ggagttttgg ggcttgttgc taacaagata gtggaaaaac tgcataaacc
      661 aacaattgtt ttaactaaaa acgatgaagg ggagattaag ggatcaggtc gttcattcag
      721 tggttttaac ttatttgatg ctcttaatcc gttaaaagaa agtctattga ccaaatttgg
      781 aggtcatgat tttgcttgtg gtttatccat ggaagaagac aaagtaaatg acctacggaa
      841 aaagtttgaa gccgattttc atgttgacgg tggtttagag actaaagagt acgatatgga
      901 attgcctatg catgacttat cacctcaaac tttggctcaa attaatcaag tgggaccatt
      961 tggtactggt gatccgcagc caatttttag tatttcggat ccaactatta cacacttttt
     1021 caaaatagga aaagataaga atcatgttaa attaacagct aataaaaaag acggcaattt
     1081 agcaattgtg ggatttaata aggattattt gaataataat ttgttaccgt ttatttcaaa
     1141 aatctttgtt actctctctt tgaatactta tcgcaaacaa gtatctttgc aaggcatcat
     1201 ggaaggaata gcctttgcat ccccaaaatt agctgtgcca acatcagtaa ttgatttaag
     1261 acaagagaaa tttgtcatgg gccttgcaga tcgttatttg ctttttgaca aaaagaatat
     1321 tccaattgtt aagaatagcc ttcaaattga tgatgataaa attagcttgg ttaaagatta
     1381 tgatcaatcg ggtgaaacag tagctttgct tgatgtgcct cgcaatcaag tggaattaaa
     1441 tgcagcttta aaaaaagatt atcaacaaat ttatttatgc tttttattag atcagttacc
     1501 tgttgaacaa attccagcaa agagttattt cggaaaagtg ttaaagtata tttatgccca
     1561 tccagcatta aagcctgaag actatcgcac tgtagcacca tatctaggtt tggattatga
     1621 tagtgtattg tttattttgc gagtattctt tgaattaggt tttgttaaat tagacgatca
     1681 aaaattagtt ggtgagtcta atccaaagaa gcaaccattg acagcttcta aatatttaat
     1741 ggcaacgagt tcacaaatta aatttattaa tcaactaaga acgatgccta ctcaaaaatt
     1801 aattacatat gttaataatt tggtaaaaag atagataaat atcaagattt cagtactttt
     1861 ataacaaatc tttggtaaaa tatacaagtc aaaagtgttt gaatacaaac gcacagaatt
     1921 atggaggttt ttcttcttat ggcgattgat tttagtaaat atattgcaag tgttaaggac
     1981 tttcctaata agggaattgt ctttcgcgat attacaccta ttttgcaaga tggtgaattg
     2041 tatcgtattg ctactcatga attggcagaa tatgcaaaga gtagaaaggc agatgtaatc
     2101 gtaggtcctg aagcacgtgg ctttattgta ggctgtcctg ttgcaactga gttaggctta
     2161 ggttttgttc cagcaagaaa gccacataag ttgccaagag aagttgaacg tgcttcatat
     2221 gacttggaat acggttcaaa tagccttgaa atgcataaag atgcaattaa gcctggccaa
     2281 agagttgttc tctgtgacga tttaatggct actgcaggta ctttaagagc ttctaaggaa
     2341 ttaattgaaa atcttggtgg taagcttgta ggtgctgcat tttacattga attgcctgat
     2401 ttaaagggta gagaaaagtt gcctgatgtt gatatttaca gcttagtgca atatcatggt
     2461 gcttaaataa attcaatatt gatctaatta gtaaaggtca ttatactaaa agtgttgtac
     2521 caacattgac tggtgcacaa tcaacagaaa taaaaataat actcctaagg aaattttact
     2581 taggagtatt tgtttacaga aattaagttt taagcattaa acaatgcagt tgaaaggtaa
     2641 cgatcaccgc cgtctggaac tacagtaacc acagcatgtc ccttgcctaa ctttttagca
     2701 atttcgattg caccatggat gtttgcacca gctgaaatac caggtaagaa gccttcgttt
     2761 ttagctactt cacgagctgt agccattgct tcatcagtag aaactgtaat tatatcatcg
     2821 tagatatcct tatctaaatt cttagggatg aaacctgcgg caataccttg gataccatgt
     2881 ttacctgttt ttccatcttt taagagtgga gattcagttg gctcaagtgc aaatatctta
     2941 gtggatggat tttcacgcct aagtgcatgt ccaattcctg ataaagtacc accagtacca
     3001 acaccagcaa caaaggcatc aacggatttg ccgataccat tcattgcggc aataatttct
     3061 ggaccagtag ttaattcatg aatattagga ttttctgtat tttcaaattg cattggcatg
     3121 aagtagcctt tttctttaac taatttttcg gccttagcaa ttgaaccctt cataccgtct
     3181 gcacctggtg tcaaaataag ttcagcacca tagcccttca ttaatttacg acgctcaacg
     3241 ctcatagttt ctggcataac aataataatg tgatagtcct tagctgcagc aaccatggct
     3301 aaaccgatac cggtattgcc tgaagtaggt tctacaattg tgccacctgg ctttaggttg
     3361 ccttcacgtt cagctttttc gatcatagct aaagcaattc tgtctttaat tgaaccagct
     3421 gggttttcaa attctaactt tacatagaca tctgccgcgt cgttaggtac aacgcgattc
     3481 aacttaagta atggagtgtt gccgataagt tctgtaactg aattataaat tgtagacata
     3541 atgtatgcct cgttttattt atctaataat actaatttgc tttttttaac ttgagttagc
     3601 cagttattga aaaatgtttt ctgagtatct ttccattgaa acaatagatt tgataatgaa
     3661 taattttctg gcttcttata atgtcgctct ggatgtgcag caatctctct ttcatattct
     3721 tttttaaggc cttttcggcc atattcgata tgagagaaaa taaaattttg ctcagacttt
     3781 tctaaagaag agaccataaa tagatgccca ttatcgtcaa ctgaattaat ggttaatcgt
     3841 ggatcttgca taatctgtgt tttatccatt tcagcgtaac gagcatgtgg agcgataaat
     3901 cctttgctga gtccatttaa taaaggatgt ggttcgataa ttaaatgagg aaaaacacca
     3961 aagatttttt tcgataaaat tcttttttga atattgtaaa aataatctaa agcggccatt
     4021 gcaccccagc aaaaatataa ttgctgcaac ttgtatttat ctaatagttg gagcaaacat
     4081 cggacttcct cgatgtaggt aacttgatca aaatcaagat gatctaaagg tgcgcccgta
     4141 atgataaagc catcaaactc tttgatttga ttaagatcta atggctggga agtttttgca
     4201 acttcaggtg ggacaggacg attttgataa tgcatacgtg gataaaagaa agtcaggtct
     4261 gcatctggca aaacgcgtgc aaatctttgt tgagtatcta acttatcgtg cattaaattt
     4321 aaaacgccta tttttactct attagccaag ttttatcctc cttacttttt aatagttatc
     4381 attatataac ctataaaaaa taagtaaaga aataaaactg catttttaaa atacaaagta
     4441 aaccccctat cggatagacc gatagagggc ttttcattaa aaaataggtg ataataatct
     4501 tgagaagtat tgcttaaatt ttaaccatga tgattgttga gcaaagtagt cattagttaa
     4561 aagggtacat ttatctaagt ccttctcaaa aattttcttt aattcttgag ttaaagcagg
     4621 gttgtagttg aatgagttta cctcaaagtt taatgtatag ctccggaaat cttgattggc
     4681 ggaaccaact gaagaaatat tagaaccgct aaccatagtt tttgcatgaa taaaaccatc
     4741 attatatttg tatactttaa cgccatgggc tactaaatac ttagcatagt attctgtagc
     4801 aggataaaca aatggatgat cgggcatgca aggaaccata attcgaacat caataccgct
     4861 gttagcagcg ataattaagg tttcaagaat tgattcttcg ggaattaaat aaggcgtttg
     4921 aatataaatg tattttttag ctcctgcaat aattccctca gcctcgtctg atgccgtaat
     4981 gttgattatt aggtcctgag gaaacaattt gcatagcgac atttttatta tcattgatat
     5041 cttttcgatt gacagtaaat ggtttaagtt cctttaattc aaatttaggt aaatttgttc
     5101 ttctgattga cgtgttccag tccattgcaa accggacctc cattaaaatt ggtgattgcc
     5161 caattacacg taaatgggta tcccgccaaa gaccgaattt tggtaattta ttgacatatt
     5221 gatctccaat attaaatccg ccaatatagc caatatggtg gtcaataata actaattttc
     5281 tatgtaagtg gtaattgagt cgtggggtag taaaccagtg cttttttgaa gtggaaataa
     5341 atggctgagc ttcgccgccc aattctctta aatggtcaaa aaagcttggc ttagtgcctc
     5401 ttgatccaga ggtatcataa attactctta ccttagcacc attagctgca gcctcttcca
     5461 aggcttttaa aacacgatgc cctaattggt tagaataaaa agtataaaat tctaagctga
     5521 cagatttttt ggcatttttg atatcagtaa tcatttggtc aaaaagttct ggtccagaaa
     5581 taaatacttt gacctgatta tcaaaagtta aaatcgcatc atcgttgtta agatttagtt
     5641 ccgaaagcat ttttactcgt ggaagacgct ctttttcagg tagaagatcg tgctctttaa
     5701 gcatgttgcg ttgctcagct aaataatgtc tttgtacctt ttttgctctt cttgaatagc
     5761 aaagatttca tcatgtgaaa gctgacgacc aaagaaaaga tataggataa aaccgatacc
     5821 gggcagaacg gttaatacaa gcatccatgc ccaagttgca acaacgctgc ggcgacttct
     5881 aaagaccgtc catacagcaa acgcaatatt gataatccat aagacttcga tagtcctacg
     5941 gattatatcc caagttaaaa tcatgaatta agtagtgtta taaataattt tagcagaatt
     6001 aagcaaatag ttataaaaca gatgagtaaa aaatgcttcc aattcgataa tttttgataa
     6061 aataagggat ggagaatggt ataaacacta cgggggtgga ttatgatgag aaaacaaatt
     6121 atttctgctg caggtataat gttagcagtt attggattag gcgcagcaac tacacaaagc
     6181 gttgatgcag ttgttactaa tccagttaga caaggtaaga gattaaatct aactagaaat
     6241 gctactgttt ataatagaca tggtgttaaa gttggacatt taagaaaggg aaagctttac
     6301 aaagtacgtg ccataaaagt aattaatggt aatacttatg taaagattcg taaaaataga
     6361 tttgttaagg aagaagcctt cttgccatat atgaagacta ctgtaaaagt agttaataga
     6421 atcaaaaagc attcctttgt ttatgatgag aatggtgaaa aaatcccagg caaattttta
     6481 aagcgtggtg ctaaggttaa ctatttaggc cataaagaaa ttaatgaaaa accatttatc
     6541 aaaattgctg atggtgaata tgttaaggct ttgaatgcct tgactacagt tactaattat
     6601 taatcaaaaa aaacactctg aaaactacat tgtagtaatt tagttttcag agtgtttttg
     6661 ttttaagtta attatctgtt tttcattact ggttgataaa tcaaatcaat aataattgct
     6721 gcaattaatg caaccacaac ggtaattaat aagttttgcc aactaatttg agccattgct
     6781 aaaccgcata aagctaaaat aaaggttaat gcgacatcgg caatttgaac aatacctaca
     6841 agtttagatg ggtaatcttg ccagaagtat ttacgagttc tagtaattaa tacaattaac
     6901 attgcactta gaactaagta aacatagacc atggtagaga tagaattgtg actccagcca
     6961 tgcatgttga ggtagctgaa aaaagcgata ccgataactg tccaacctgc agcaagagag
     7021 aatgcgattt tggctaacct tgccatattc caattttctg gtttgtaagt aatatgggta
     7081 cggtcggtac caatcatcat ggtaaccatg ttattcatga ttgtgtaaat aaccatagca
     7141 tttaatgcca ttggaatata gttgaagaag aaatagccga aggttaaaag catagttaat
     7201 tcggcggttc tggcgagctt agcaagtgac caagtagtca ttcgttgata tacacggtga
     7261 ccagcatcaa gaattttaac aatagagctt aagccatcat ctagaagcac catcttactt
     7321 gaacgcttgg caacatcggc agcgttagaa acagcaatac caacttcagc ttgctttaaa
     7381 gcaggagagt cgttaacacc atcaccagtc ataccaacga tataaccttt ttcttggaag
     7441 aatttaacca tcttaagttt atcttcaggt aaaacatcgg caattcctgc taattcatca
     7501 atatcggtgc tttcatcaaa gtcatgaata gagataacgt taccagttaa atcaacttgt
     7561 tcagcgactg ctgcggcagt tctttgatta tcaccagtta acatgattgg acgtacgccc
     7621 cgttttttaa gttctgctaa agcagcctta gagtcctttc ttactttatc ttgtaagata
     7681 aatactcccg caagtttgtc atcaattaac acggcaactg agcgtccagc tttaaaattg
     7741 atgccttcaa ctgcttcatt tgcattctta tcgattaatg aaagttgctt aaatgaacct
     7801 aacttaacat tgtgaccatc tacttcagcc atagaatagc cagtgtcaga agtaaatggg
     7861 gtaaagtgtt caacgtccat gacagggata ttgttttctt ttaagtattc atcaatggcg
     7921 atatcaatga tacctgtatt gcgcttatca gttgcactac cggctaaagc aagtacatct
     7981 ttatctggca aatcgcttaa attgctccaa ctagcaactg cagttttgtt ttcagtgatt
     8041 gttcccgtct tatcaagtaa aagcaagttt aagttagctg catcttggat accagttaaa
     8101 tcagctgtta agacgccttc tttacttaaa cgggttgctt caaatgaatt ggacaatgca
     8161 aaggttgacg gcatcgcaac cggaattgaa gcgatgaaca tcatggctaa gaatggcaac
     8221 atgttgataa acgtatcaaa attaccaccc ttaaagaatg aagcaatgat aataactaag
     8281 gtaagtacac cgtcaagtag gcaaaggtag taaataatct tagttaaaag ttgttgcaag
     8341 tgaccaggtg cagctgaatt gttgatcaag ttaatggtct taccacttct tgaatcttta
     8401 ccagttgcag taacaattgc taatccatcg ccttcaacaa cagtagtacc agcataagct
     8461 gtgtcatcaa tgttcttttt aacgggctta gattcaccgg taattgagct ttcatcacag
     8521 gcgatcttac cgctaaccat ttttacatcg gctgcaagta catctccacg ttgaagtgag
     8581 attaagtcgc ctctaactaa ttgcttagag tcaattttga tccacttacc atcgcgttct
     8641 acagccacct taggggttag cttatgtgaa atggtattta atacccgccg tgactgtttc
     8701 ttcttggatg caccgttaaa agccgcaaaa agaagcatca acaagacgaa caaagattga
     8761 atccatttgc ctaagataca ttcgaggatt aaggcacctt ctagaaccca ggcagaaaga
     8821 ttccataatt ttgatagaaa ttccttaaaa aagttgtatt cgggttcagg tgcttcgttt
     8881 aacccatctt ccttaagtct cttatctgct tcggcttgag ttaagccatg aaatttttca
     8941 gacattttat tccctccaaa tctaccttaa taaagtagca catatgttgt ttgaatgaaa
     9001 atactaaatt aaaatataag atatagaaat ttttaataag agatacaact aaaataaaaa
     9061 agatagatta ttaatgaata ttaaacaatt acgctacttt ttagtagtag ccaaagaaaa
     9121 gcaaatcact tcagcagcta aaagactata cattgcacaa ccgccgctga gttatcaatt
     9181 aaagcaacta gaaatagaac taggagcaca attatttaag cgtactgctc atggaattga
     9241 attaacagat gctggacaaa ttttgcagag ctatgctagt gaaattctct ctttatcaga
     9301 aagcgtgaaa aatcaggttc ataaaactgt ttcaggtgaa ctaggcacga ttgcaatagg
     9361 catggcttca tcatcaactg gactaattcc tatgaaaagt tttcaagatt taactaagtt
     9421 ttatccggaa attaactttg atatttatga agataatacc tttggcatta tcgataaatt
     9481 ggaaaagaag acaatcgatt taggaattgt gcgtacgcct tataatcgta atggcttaaa
     9541 tgcaaaaact ttaactactg aaagaatgat ggcagttact gttgatccca aatttaagga
     9601 taagacggaa ttaaggatta aagatctaaa tgagcagccc ctcattattt atcgaagatt
     9661 tgaagaaatt tttaaccaga cttttgctca tcatgggatt aagccgtttt atgctgttaa
     9721 atgtgatgat tctagaacag cgattacttg ggcgaagaga aaaatgggga ttgctcttgt
     9781 tcctgaatct attgcttcta cgtatgcgcc tgatgatctt attcctatta aatatagtaa
     9841 ttggattacg catttgcaat tagtgaggcg caaggatcaa aaggtgacgc ctttaatgaa
     9901 aagaataata gattcactaa gccgttaaga ttgtaacttc tacctaattg atccttaatt
     9961 attgtaagtg gatacataat ttgaattagg aggcgctata atgactgact taattcatgt
    10021 ttattccgaa attggcaaat tagaaacagt tatgctgcat cgaccgggaa gagaattaga
    10081 aaatctttca ccggatatct taaatcgaat gttaattgac gatattccat atttaaaaat
    10141 agctcaaaaa gagcatgact attttgccca cactttggaa aaatagggag ttcatgtcgt
    10201 ttatttagaa gatttattag ctcactcttt gactaatgaa gatgtccgta caaaatttgt
    10261 agatcaatta ttagaagaat ccaatataaa aaagaagatc cattacataa attactgatg
    10321 gactatttaa tagcaatgcc agtaaatgaa atggttaagc aaataattgc tggtattaga
    10381 aaaaatgaaa tgcaaaatgc aactccttca ttagccgatc tagctgaaga tccagattat
    10441 ccattttatt tggatccaat gccaaatgtg tattttactc gtgatcaaca agcagctatt
    10501 ggtaatggca tgactattaa tagaatgacg tttagagcta gaagacgtga gtcattattt
    10561 atggaaaccg ttttaaagca tcatcccgac tttaaaaatg ccaatattcc tatttggcgt
    10621 gatcgttaca ctcatggacg tttagaaggt ggcgatgagc tgattttaaa caatcatgtt
    10681 tttagcaatc ggtatttctc aaagaacttc cgctgccgca atcactgacc ttgctcatag
    10741 cctgtttggt cattctagtt atgacacaat tttagcaatt aaaataccac ataatcatgc
    10801 catgatgcat ctggatacag tctttacaat gattaattat gattagtgta ctgttcatcc
    10861 ttttatttta gacaaatcag gaaagattga tatttatgtt ttagagcaag atgatcatgg
    10921 tgagattaaa attaccccag aaactgattt gatcaaagtg ttaaagaatt atttgcactt
    10981 atcggagatt gacctaattc caaccggagg tggggatgca attgcagccc caagagagca
    11041 gtggaatgat ggctcgaata ctttggctat tgcgccaggt gaagtcgtta catatgatcg
    11101 taattatgta tcaaatgatt tgttaagaaa gcatggcatt ttagttcatg aaattcattc
    11161 aagtgagctt tctcgtggcc gtggaggtcc aagatgtatg tcatgtccac ttgttcgtga
    11221 agatttgtaa gaggcgtcaa aatgaaatat ttacaaaatg tgtttcaagg cagaagttta
    11281 ttaaaatgca aagactatac tccaacggag cttaactatc taattgattt tgcacttcat
    11341 ttgaaggaac taaagaaaat attccgcatg aatatttaaa aggaaagaat atagctcttt
    11401 tatttgaaaa atcttcaaca agaacacgtt cagcctttgt agttgcatgc aatgatttag
    11461 gcgcaaatcc tgaatatatg ggtgctggtg aaattcattt aggtaaaaag gaaagtattg
    11521 aagatactgc caaggttttg ggcagtatgt ttgatgacat tgaatatcgc ggttttgctc
    11581 aaaaagatgt agaagatttg gctaaatatt ctggtgtccc tgtttggaat ggtttaacag
    11641 ataaatggca tccgacccaa atgttggctg actttatgac tattaaagaa aagtttgtac
    11701 atttaaaggt acttacttta acttatgtag gcgatggacg tgataatgtt gccgacagtc
    11761 ttttagtggc tggcagcatg cttggagtta atgtacacat agttacgcca aagcctttat
    11821 tcactcaccc tgatgtacaa aaaattgcag aaggttttgc caaagattct ggatcaagaa
    11881 atttgattac tgatgacatt gaacaaggcg ttaaaggtgc aaatattatt tatactgatg
    11941 tctgggtatc aatgggtgaa aatgactgga gtgagagaat caaattgtta aagccttaca
    12001 cggttacaat gaatatgatg tatatgacag gcaccccgga tgatcaacta atctttatgc
    12061 actgtttgcc tgcgtttcat gattgcacta ctaaagttgg caaagaaatt tatgaaaaat
    12121 atggtctaag tgaagtggaa gttacagatg aagtctttaa ctctcaatac gcttggcaat
    12181 ttactgaagc ggaaaataga ttgcattcta taaaagcaat aatggccgct actttgggca
    12241 atttgtttat tccgtcagtt gatgaaggaa gtaaataaag atgaaaagaa tagttgtagc
    12301 tttgggtggc aatgctattg aagcaggtga taatagtgca gctgcccaag aaaagcaggt
    12361 taaaaagaca atgaaggttg ttgctaaaat gattgaaaat ggtgatcagg tagcgattgt
    12421 tcatggtaat ggcccgcagg ttggtaattt gcttttgcaa caatacaaag gttcaagtaa
    12481 agataatctc gctatgccgc ttgatacagt agtatcaatg actcaaggca gtatcggcta
    12541 ttggatgcaa aaggccttag acgatcaatt taaacataca aattatccac atcaagctgt
    12601 tgctttaatt actcagataa tagttaatgc gaatgatcca acttttaaga atccaactaa
    12661 accaattggc ccattttata catttaacga aatgcagagg taaaaaatct atcatcctga
    12721 atatacttat aagcaagata caggtcgagg ctatcgtcaa gtagtttctt ctccaaagcc
    12781 cgttaaaatt attaatgcac caggcattga cactttacta aagagcaagt ttgttcctat
    12841 tgctgccgga ggtggtggaa ttcctgttgt agtgaaagac gatagtttgc aaggcgtagc
    12901 aggagtaatt gataaagact tcagtgccgc aaaactagct gaagatattc aagtagatga
    12961 attagttatt ctaactactg ctgacaatgc ctacgtgaac tataattaac ctgatcaagc
    13021 tcctattgga aaaataaaga ttgatcaatt aaagaagtat ctagaagctg gccaatttgc
    13081 tgcaggcagc atgaagccaa aaattgaagc tgtcattgat ttcgtagaga aaacaggaaa
    13141 gactgcaatt attacttctt taagaaatgc aagtaaactt gatgatggag taggtacaat
    13201 tgtttataat taactgcggt gagatataaa tgaacatttt tcaagaagga aatccgcaaa
    13261 atattgctca ggtattagct ggaaaagatt atcgtgtagc tttgcagcaa gctattttta
    13321 aaaagtatcc tgatgcgact ttggttgata taaacttaaa tatcccgggg ccaattaaaa
    13381 ataatcgata tttaatcaaa ttatttgatt acggaattaa acaattagaa gaaatatggc
    13441 agaataaggg atatgactat aaattagtaa aagcattaaa taatgatgct ggatgtgaaa
    13501 atttctatgt tttgcgagaa tctagcaaag tagttaaatt atctacaatt ttatttgaag
    13561 aaaataataa aataggacga ttatttgatg ccgatgtatt aattaaaggg aaaactgcac
    13621 tttcacgcca agagcttgaa tactctagtc gccgctgcta tttatgcaat cgccctgcta
    13681 aagagtgtgc tcgatcacgg cgacactcag tagaagagat gcaaagatac atttctagtt
    13741 tatatgcgaa gtatgtaaat aattaaaacg ggatgggagg ctaatcatcc cgttttttca
    13801 tttaaatctt aaaaaaagct aacgaaaaat acataaaatg ttctaaaata taagtaaagt
    13861 tatgaatata tattgtaagg aaaactatga aattaaagaa aaaccaagac aatttaaaac
    13921 aaattgcttc attgattgaa tatgcttttt taaaagattc tgatttgact acagatagta
    13981 actttatgcc ccgatatgat catagtgatg gatatggata ttttgatcaa gaaaaattga
    14041 ccagttatat gatggtcaat aagtttaaag ctgagatatt tggtcatcat gttccactgg
    14101 caggtattgg ttatgtggca tcatatcctg aatacagagg acgtggacat atatctaaat
    14161 taatgaaaga aattcttttt gatttgcatg atcaaaaaat cccagttgca aatctagctc
    14221 cattttcaga aaaattttat cgtcattatg gttttagcaa tagtatttac caaaaagaat
    14281 atcgcttttc gggggctgca cttgcttctt tcagattacc acgcaaaggt aagataattc
    14341 gtggaaaatg gaatgatttg attgttcaaa atggtgtgat tcaattatat gaacgtcagt
    14401 tgcatactga cgatgaaaga aatacgatca tcagagaagc ttggtggtgg aatagattag
    14461 atgattatta tcatcatcga gagattgctg tttacttcga tgaagctggt cgaccgatga
    14521 gctacttgat ttatcgcata attgataact gttttatggc tgatgaatta tattcaatta
    14581 cgcctcaagg attattaagc atattaggct ttatggcagc tcatataggg tcaattaaag
    14641 agttttgtat gacattgcct gagaagtctt tattggctga actttttcca gagcaaaatg
    14701 aattggatat tcaacttcat ccatatatga tgagtagaat tattgatttc caaaaagtct
    14761 tggcatgcat gcgcccattg caagagggta cttttaacat cgaagttaat tatgatgatc
    14821 agtgtccatg gaatattggc gtttggcaat taactaatta tgatcaccaa gttaagtgtg
    14881 aacgaaaaga agatgaacta gttgatttct ctggtccaat tacaacatgg actcaaatct
    14941 tattaggacg tttaactatg gaatccgcaa ttaaacttgg tttgatcaca gattatcgaa
    15001 ttaaaaagtt ggactttgta aaaggtaaag tctcatttta tgattatttt tagaagaagg
    15061 tatccaaaat gagtaagcaa aagaaagtta gattactaaa atttttaagc gtggtagtta
    15121 gtggaataaa tgtggttatt tcgctattga ttatgttcaa caaatatcaa attagaaaag
    15181 ataaaaaaca aatatcagat gaaggtcatg ccccattgga tgaaaattaa ctatgaaaaa
    15241 attgagaata gcatacttta accaacttgg tagaagacaa ttagatcgaa ttgtagacca
    15301 atttaagcaa aaacattctg atgtagaaat tgaattaatt ggaatgggac acgatgaagc
    15361 ttttgataaa ttagccaaaa atgaagttga tttagcgatt agtgatttgc gcgatgatca
    15421 gctcgatttt aagaaagaaa tcttaggtca ggaagcagta atggctattt tgcaaaaggg
    15481 tagttatcct agcggtgttc agatgatcaa taaagatgat ctagctgatt taacctgttt
    15541 tattgtagct aagcctgaag aagaggctgc agaactccat ttatttaaag atatttatca
    15601 gattagaagc ccattcattg cttcaaattc cgtagaagag gcagcattgt tagtagcttc
    15661 tggatcagga tattttttaa tgaatgaagc aaccgccagt ttaattagta atgatacttt
    15721 acaacgattg tttttattgt ctaatggaca acaaatgtgg caaaagattg cagcttttta
    15781 taccaatgaa gatgcagtaa ttaaagattt tattttgtta gctaaaaaag tatattaatc
    15841 tatcttggaa cagcaaaata ctgtaaaaat aaaaatgcgc tgattgtaaa attaagttga
    15901 acacttgata aaaaataaaa agtccattcg gacctgtttg atagaatgta gttaccacac
    15961 aacatttaga aacgaggtca aaatggactc tttacattct accatgaatc agcacattaa
    16021 aggcaagcat ttatcattcg aggaaagagt tattattcaa ttgcgtttga aagatggcta
    16081 ttctttgcgt gccatcgccc gtgaattaaa ctgttctcct tctactatca gctatgaggt
    16141 taagcgcggt actgtagaac tgtatcatgg caaagtcaaa agatataagg ctactcaagg
    16201 gcatgatgca tatcaagccc atcgtaaaaa ttgtgggcgc aaatcagact ttctcaggaa
    16261 aactcaattc atgcgctatg tccacaagca tttctttaaa gacggctggt cgcttgatgt
    16321 gtgcagtaat cgtgccactg ctgttggcgc atttagcagc agagatgttg tctgtactaa
    16381 gactctttac aattatgtcg accaaggtct attagatata cataattacg acttgccaga
    16441 gaagcttaaa cgcaatacca agcttcatcg tattcgcaaa aataagaaaa
//
