GCA_018993325.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaLHEJKOMA_1 (original name was: gnl|Prokka|LHEJKOMA_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	RiPP-like	40,799	52,910
Region 1.2	cyclic-lactone-autoinducer	527,865	548,570

gnlProkkaLHEJKOMA_2 (original name was: gnl|Prokka|LHEJKOMA_2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS-like	1	30,399

gnlProkkaLHEJKOMA_23 (original name was: gnl|Prokka|LHEJKOMA_23)

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	terpene	24,663	45,544

Region	Type	From	To	Similarity
Region 1.1	RiPP-like	40,799	52,910
Region 1.2	cyclic-lactone-autoinducer	527,865	548,570
Region 2.1	NRPS-like	1	30,399
Region 23.1	terpene	24,663	45,544

No secondary metabolite regions were found in these records:: gnlProkkaLHEJKOMA_3 (original name was: gnl|Prokka|LHEJKOMA_3); gnlProkkaLHEJKOMA_4 (original name was: gnl|Prokka|LHEJKOMA_4); gnlProkkaLHEJKOMA_5 (original name was: gnl|Prokka|LHEJKOMA_5); gnlProkkaLHEJKOMA_6 (original name was: gnl|Prokka|LHEJKOMA_6); gnlProkkaLHEJKOMA_7 (original name was: gnl|Prokka|LHEJKOMA_7); gnlProkkaLHEJKOMA_8 (original name was: gnl|Prokka|LHEJKOMA_8); gnlProkkaLHEJKOMA_9 (original name was: gnl|Prokka|LHEJKOMA_9); gnlProkkaLHEJKOMA_10 (original name was: gnl|Prokka|LHEJKOMA_10); gnlProkkaLHEJKOMA_11 (original name was: gnl|Prokka|LHEJKOMA_11); gnlProkkaLHEJKOMA_12 (original name was: gnl|Prokka|LHEJKOMA_12); gnlProkkaLHEJKOMA_13 (original name was: gnl|Prokka|LHEJKOMA_13); gnlProkkaLHEJKOMA_14 (original name was: gnl|Prokka|LHEJKOMA_14); gnlProkkaLHEJKOMA_15 (original name was: gnl|Prokka|LHEJKOMA_15); gnlProkkaLHEJKOMA_16 (original name was: gnl|Prokka|LHEJKOMA_16); gnlProkkaLHEJKOMA_17 (original name was: gnl|Prokka|LHEJKOMA_17); gnlProkkaLHEJKOMA_18 (original name was: gnl|Prokka|LHEJKOMA_18); gnlProkkaLHEJKOMA_19 (original name was: gnl|Prokka|LHEJKOMA_19); gnlProkkaLHEJKOMA_20 (original name was: gnl|Prokka|LHEJKOMA_20); gnlProkkaLHEJKOMA_21 (original name was: gnl|Prokka|LHEJKOMA_21); gnlProkkaLHEJKOMA_22 (original name was: gnl|Prokka|LHEJKOMA_22); gnlProkkaLHEJKOMA_24 (original name was: gnl|Prokka|LHEJKOMA_24); gnlProkkaLHEJKOMA_25 (original name was: gnl|Prokka|LHEJKOMA_25); gnlProkkaLHEJKOMA_26 (original name was: gnl|Prokka|LHEJKOMA_26); gnlProkkaLHEJKOMA_27 (original name was: gnl|Prokka|LHEJKOMA_27); gnlProkkaLHEJKOMA_28 (original name was: gnl|Prokka|LHEJKOMA_28); gnlProkkaLHEJKOMA_29 (original name was: gnl|Prokka|LHEJKOMA_29); gnlProkkaLHEJKOMA_30 (original name was: gnl|Prokka|LHEJKOMA_30); gnlProkkaLHEJKOMA_31 (original name was: gnl|Prokka|LHEJKOMA_31); gnlProkkaLHEJKOMA_32 (original name was: gnl|Prokka|LHEJKOMA_32); gnlProkkaLHEJKOMA_33 (original name was: gnl|Prokka|LHEJKOMA_33); gnlProkkaLHEJKOMA_34 (original name was: gnl|Prokka|LHEJKOMA_34); gnlProkkaLHEJKOMA_35 (original name was: gnl|Prokka|LHEJKOMA_35); gnlProkkaLHEJKOMA_36 (original name was: gnl|Prokka|LHEJKOMA_36); gnlProkkaLHEJKOMA_37 (original name was: gnl|Prokka|LHEJKOMA_37); gnlProkkaLHEJKOMA_38 (original name was: gnl|Prokka|LHEJKOMA_38); gnlProkkaLHEJKOMA_45 (original name was: gnl|Prokka|LHEJKOMA_45); gnlProkkaLHEJKOMA_56 (original name was: gnl|Prokka|LHEJKOMA_56); gnlProkkaLHEJKOMA_64 (original name was: gnl|Prokka|LHEJKOMA_64); gnlProkkaLHEJKOMA_65 (original name was: gnl|Prokka|LHEJKOMA_65); gnlProkkaLHEJKOMA_66 (original name was: gnl|Prokka|LHEJKOMA_66)

Compact view

gnlProkkaLHEJKOMA_1 - Region 1 - RiPP-like

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Location: 40,799 - 52,910 nt. (total: 12,112 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaLHEJKOMA_1 - Region 2 - cyclic-lactone-autoinducer

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Location: 527,865 - 548,570 nt. (total: 20,706 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaLHEJKOMA_2 - Region 1 - NRPS-like

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Location: 1 - 30,399 nt. (total: 30,399 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 30399:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg2_6

AMP-binding (40..421): X

nrpys: Gly, Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: FLFSAGGPIK
Nearest Stachelhaus code(s):: Ala DLFFCGGPLK (29% 8Å match)
Stachelhaus code match:: 60% (weak)

ctg2_8

PKS_AT (7..289): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 58.3%; 2-Methylbutyryl-CoA: 54.2%

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 21.1
Malonyl-CoA: 9.2
inactive: 0.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg2_10

AMP-binding (31..384): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGLIHK
Nearest Stachelhaus code(s):: Orn DVWNIGLIHK (56% 8Å match)
Stachelhaus code match:: 90% (moderate)

gnlProkkaLHEJKOMA_23 - Region 1 - terpene

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Location: 24,663 - 45,544 nt. (total: 20,882 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.