LOCUS       gnlProkkaOPBPABKL_68   15214 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OPBPABKL_68.
ACCESSION   gnlProkkaOPBPABKL_68
VERSION     gnlProkkaOPBPABKL_68
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 07:55:42
            Original ID  :: gnl|Prokka|OPBPABKL_68
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 147789
            Orig. end    :: 163003
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15214
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15214
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15214
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(504..1316)
                     /locus_tag="ctg68_142"
                     /transl_table=11
                     /translation="MISLTKNNELKGYKSLDVYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVSVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDHLNQKF
                     GTQGEDVVACIGPSISLESFEVGDEVYDAFKESGFDMSLISMKKKETGKYNIDLWEANR
                     IELLNAGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRILSGIMIRK"
     CDS             complement(1313..2479)
                     /locus_tag="ctg68_143"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVILLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYDDNVDDDDDDIDYEYEEEDWEEK"
     CDS             complement(2595..3164)
                     /locus_tag="ctg68_144"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             complement(3232..3768)
                     /locus_tag="ctg68_145"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSSGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3810..5354)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 47.5; E-value: 1.6e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg68_146"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAMMMAVGQFLMFMSASTLDNTE
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKAEHISHPKMDKRTKLRNTLVITILTVALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDILGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWSFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5559..5783)
                     /locus_tag="ctg68_147"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             6846..8357
                     /locus_tag="ctg68_148"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPITSIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCLTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8430..9497
                     /locus_tag="ctg68_149"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             9534..9818
                     /locus_tag="ctg68_150"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10001..10351)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_151"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-10, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.3e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(10449..11837)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg68_152"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(12085..12480)
                     /locus_tag="ctg68_153"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(12487..13260)
                     /locus_tag="ctg68_154"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(13266..13793)
                     /locus_tag="ctg68_155"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(13780..15021)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 387.1; E-value:
                     2e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg68_156"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(15031..15213)
                     /locus_tag="ctg68_157"
                     /transl_table=11
                     /translation="MIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYYEK
                     RDDSDKLKLDTVDED"
ORIGIN
        1 ttcgatattc aacaccccgc gtccgatacc ttcaaacggt tctccagctt tgccgatacc
       61 gagttcaagg tgcgtacctt gtattttatc cgcatcgaaa ccaccaatag aatgtcccgt
      121 acgaagagac acgaggttaa tcaggtctac cagtgtatca atctgatata gcgggattcc
      181 acgcatcagg cggcggcgta gagcttcggc tgacgggcga taacgtccgg ggtctttgcc
      241 acaacgttta taagcctcac gggtagcaaa gataacgggt tgatgtttga tgtcttccat
      301 ctgtgtagtg gaagtcagtt gcctggtaaa agcgttgatt tcctgccaaa gcccttcgtt
      361 gtaagcagta ttcttcactg cagcatacac ggcggctccg gcaaaaaccg ggcatgcgtc
      421 ttttatttct ttagatactt ttatttcaaa cataacttat cataaaccaa tcatcagcgt
      481 cctgcaatta cggacaccaa ttattacttt ctaatcatta ttcccgacaa gatacgaccg
      541 gaatctattc ccagtctacg tgcggagaag aattcatcat gatgaatata ggtacagatg
      601 ccagctactt ctatctgttc tgcaggcact ccggcattca gtaattcaat ccggttggct
      661 tcccacaaat caatattata tttgcccgtc tccttcttct tcatagaaat aagagacata
      721 tcgaaaccgc tttctttaaa agcatcatac acctcatcac ctacttcaaa tgattcgagc
      781 gaaatgctcg gcccgatgca agctaccaca tcttcgcctt gcgtcccgaa tttctgattc
      841 aagtgatcca tcacatgact gacaatatgc ttcacagttc ctttccatcc ggcatgaacg
      901 gcagccacaa cgtgttgttt tttgtcgtac agcaatacag aaacacaatc cgccgtcgtg
      961 acgcaaacgc aataccccgg cacattagtt atcaaggcat ccattcctcg caaaagtagc
     1021 cgtctcattt ctaatgactc tttaaaaaat gattcattga taatcagact ggcacaacca
     1081 tggctctgtt caggaataaa caactccttt atctgatgat tcatgcactg aaacaaccag
     1141 ctctgattgc gattgacgtt catacatgag tcgttggtat aaggcgaaca gttgaaagag
     1201 ccgtaagctc cggtgcttat accttcgtga cgcgttgtta cgaaatgagc tacctcggga
     1261 tatacatcca gtgacttata tcccttcaac tcattatttt ttgtaagtga aatcattttt
     1321 cttcccaatc ttcttcctcg tattcatagt cgatatcatc gtcatcatca tcaacattgt
     1381 catcatattc ataaacgatg tcttcatctt cgcccatgtc tttgagctcc tgttgcagac
     1441 gggttacgtc cttcggacgg tgaacgatgt cctctatctt attgctttcc ttattcagtt
     1501 cttcccaaag aatgtctttc aacaccgaga tacccaaacc ggaaacagaa gatatgaata
     1561 cgtggggaat gccttccggc aatgtaggtt ctatttcgtc catcaattcc tgatcgagca
     1621 tatcgctctt ggtgacagcc aacacacgtt gcttgtccaa catttcagga ttgaaagtac
     1681 gcagttcgtt cagcaagact tcgtattcct tacgaatgtc gtcactgtct gccggaacca
     1741 taaacagcag taatgaattg cgctcgatat gacgcaggaa acgcagtccc aagcctttac
     1801 cctgactggc tccctcgata atacccggta tgtccgccat cacgaaagac tttccaccgt
     1861 gataggaaac gatacccaaa ttgggttcga gcgtagtaaa cggataatca gcaattttcg
     1921 gtttggcagc cgaaatagaa gaaagcaaag ttgacttacc cgcattcggg aaacctacca
     1981 gaccaacatc ggcaagcagt ttcagctcca tgataacggt catttcctgc atcggttctc
     2041 ccggctgtgc aaaacgcgga gcctgacggg ttgccgtctt gaaatgccag ttaccctgac
     2101 caccacgacc gcctttgagc aagatcactt cctgtccgtc ttctgttacg tcacaaagat
     2161 attcccctgt ctcggcatta taaacgaccg ttccgcaggg cacttctatt actttatccg
     2221 caccgtcttt tccgaaacta cgtcctttac tccccgattc accatgaccg gccattgcgt
     2281 gacggtcata cttcaagtgc aacaatgtcc agtaattacg gttaccgcgc aagatgatat
     2341 gacctcctct tccaccatcg cccccatcgg gacctccgtt aggacaatat ttctcgcgcc
     2401 tcatgtgcgt agagcctctt ccgcccttac ccgagcgaca gtatatcttt acgtaatcaa
     2461 caaaattcga ttcagccata ttctttttaa gtagttaaag tagtcagtag ttagagtaat
     2521 taagtagaat actccggcta ctgactgact tattcattta taatagtgta ttgataatta
     2581 gtaagattac taaattacaa tttatctact gcttcgcaga tttcagcaaa gataccttcc
     2641 atagtaccca agccgttgat gtgttggtat ttcttttcgt tcttgtacca gtcgatcagt
     2701 ggggcagtct gtgaatgata tacgtgcaga cgttttttga ttgtctcttc gttatcatca
     2761 gcacgaccgg aatccttacc acgtttaatc agacgtacca tcagttcttc ttccggaaca
     2821 tccaggtcaa ccattacaga aacatcctgt cctctttctg ccaacatttt ctttaatgct
     2881 tcagcttgtg caattgttct tgggaaaccg tcgaaaatta cacctttgct atctttgaag
     2941 ctgtcgaata cgcttgccag aatatcaatc attaattcat caggaatcaa ttgaccttgg
     3001 tcgatgtaac ctttagcagt tttacccaat tctgtgccat tcttgatttc agcacgcaat
     3061 acatctcctg ttgagatgtg attgattcca tacttttcta caatacgttc gctctgtgtt
     3121 ccttttcctg aacccggagc accgaaaatt acgatgttca acattttgtt atttacaatt
     3181 taacgattta ctatttacca tttaaactgg tacctattta atattaactg tttaatctac
     3241 tactgtataa atatcgggat agttgcgtcc gaaaccatca taatccagtc cgtaacctac
     3301 gataaagtcg ttcgggattt ccattgctac gtattcgatg ttcagattga ccttgagttt
     3361 ttcaggcttc actagcagag aagcaatatg gattgcttca gggttgcgtg tacccaatgt
     3421 atccaacagg cgttgcatgg ttagcccggt atccacaata tcttctacaa taactactgt
     3481 acgtccggca atgtcttcat tcagtccgat cacttcctta atcactcccg aggaagtcac
     3541 tccctgataa gaagccagtt tcacaaacga aatctcgcaa gggatggtga tgtgcttcaa
     3601 caagtcggca gtaaacataa atgaaccgtt caacacacta aggaagagcg gattcttacc
     3661 tgccaagtcg cggttgattt cgttcgctac gcgaatcact tctttctgaa tatcctgttc
     3721 cttaatagaa acagtgaact gtttgtcttt tatctgaatg gtatccataa ccggtaattt
     3781 aaaaaataac cttgcaaaaa tacgattttt tattctaccc cgtgcatcat cttctgtaat
     3841 ttcttcgaga gaaggaacag aatcaatgaa gcaacaccgg acatgacaac gaataccata
     3901 aagaaatcgt acatggtagc aatctgataa ccaaagattg atttcacttt tccggcttcc
     3961 ggataaagtc cactcaacat gcctgcaaat ttattggctg tggcagtaga cagataccag
     4021 attcccatca tcaaagaggc gaaacgtagc ggactcaact tatttaccat tgaaagtccg
     4081 ataggtgaca aggctatttc acccattgta tgaataaaat aaagtcctgt cagccaaatc
     4141 atacttacct tcactccggg gatagcatct ttcactccga aacagatgaa aagataacct
     4201 aaagaaagaa gtaacaagcc aatcgcttgt ttggtaggag aagcaggttc catctttcgt
     4261 ttgttgagga agctccacac acccggcatt atatatgcca gaacaacaac aaacagagga
     4321 ttgaaggatt gaaaccacga agccggcatt tcccaaccta aaatatcacg attggtttgt
     4381 tcggaggcaa agagagttaa agaggctcct gcctgttcgt aagccgccca gaagaaaatg
     4441 acaaagaaag ctactatata gataacgaaa atacgactac gttcgatctt ggttaatgaa
     4501 ccatccaata ggatgagaac agggaaaaca atgcaggcgg taaaaatacc gatgctcacc
     4561 cagtcaccct caaaagcgta attaaagaag gctattaaag caactgtaag aatagtgatt
     4621 acaagggtat tacgcaactt ggtacgctta tccatcttcg ggtgtgagat atgctcggct
     4681 ttatcctctt tcttttcacg tttggcatcg gggataatac cgattggctc tccggaagga
     4741 gagaaaagat atttattctt ttgagtttca aaaagtacaa cagtgaacag tgtcatgatt
     4801 ccggctgcaa gaaatcccca tttaaaatcg tgcgggtcac cggtatcgcc cagataacca
     4861 caaatcaaag gggcggcaaa agaacctaca ttcactccca tatagaagat ggtatatgca
     4921 gcatccagcc gtctgtctcc cggttcgtag agttgaccta caagagaaga aacggtaggt
     4981 ttgaaacaac catttcccaa gatcaggaat ccgagtccgc catacatcat ccagtgagca
     5041 agttccgtat tatctaaagt agaggcactc ataaacatca ggaattgtcc gactgccatc
     5101 atcattgctc cccaaaacac agagcgacgg attccccaat atttatcggc aatgtatccg
     5161 ccaatcaaag gagttaaata gactaacccg gtatagctac cgtaaatgga tgctgccgct
     5221 tctttgtcaa acaataatgc ctgcgtcagg aaaagaataa agatcgcacg cataccgtag
     5281 taactgaaac gttctgccgt gcttgtcgcg aaaatcagat aaaggccttt cggatgccct
     5341 ttcaatgcac tcatgaattt atgtgtttag tagtttatgg ggtgcaaagg tacgaaaaat
     5401 agattaaatg cttcaaaaaa agaaagttct tatcaaacgg gaatataggg ggaataataa
     5461 aaatgggcat aaaaaatcct actgatccac ttcattattt ttttagctgt gtaaataaca
     5521 aagtggagat ccatcttaaa tataggttag ctaccacctt agccaaaagt aaattcgaca
     5581 ttttcgatac tggcaaaaag cattccttct cttttcctca aaaagatttt gtcttctcgg
     5641 gccagccaac caatagcaag agctacgtct tcaaacgtca aacttaattc acggcacaaa
     5701 tcgaacattg aaagttcacc tttttcattt aagatgcgcc atactttccc ggcattcaag
     5761 ccaatttttg tcttttccat catgcaaact ttagaagatt aaacaatccg ttatttagat
     5821 tctaattcat tgtgagcaca ggaaattaat gtgatgcaca ttatctatct ccaaagataa
     5881 catttttatc ggaaacggca aataatcaaa ggcttaatca agggaaccgc attaaaaatt
     5941 tgtttaagaa ggtatggaga taaactaaac acaatttcca tccgcccctc tacagaaaaa
     6001 gatttttcat tttcatttct catattctca taaataaggc acaagtggca gtaaactaat
     6061 aagatagact atgagaaatg attttaaaac aggcatttct catagtttct tcgcaaaata
     6121 acccggattt tgcttcattt ctcatagtgt agcgtgccgg aagctgacat tgaataaata
     6181 gaactatata ttccttttgc ttgcttccat acacagtgtc ttagtcccac atattgtggg
     6241 aaaagattcc ctaaggcttg ggaaagtatt cccttatttt gtgggaaagt tttccttcaa
     6301 tatacgagaa tactttccca caatatatgg gacaatcgag aacaacgagc atctccaagc
     6361 aaaaagccac tattttatct aaatagtagc ttcatttcct gataaaaata aggcaggctg
     6421 aaagaaaaaa ggaagaaaga atggcttttg actatgagaa ataccctgaa atacgatgag
     6481 aataaggtgg cttttgagcc aaaacatggg agaacttatg agaaataccg ttttgaaaaa
     6541 gtgtttctca taagatatct atttgattat ctttcgttta tcgaaaaaca atgagaatat
     6601 gagaaatgaa atgaagaaat ctttttcagg gagaaataaa agtaagttca taatggtgca
     6661 gcattgaatt attttttagc ggagttattc taacacttaa tagtttaaaa gcagatattt
     6721 ctttgaccaa aagatagaac taatgatgaa ttaaaagttg caattatggt tttcttccca
     6781 caacaaacgg gaaaagtcag aagaatcatg tacatttgta atccgaaaac taaaagaaca
     6841 tcgcaatgaa aatatttcca agcagcagta tcaagaaatt ggacgcttat accattgaga
     6901 acgaacctat tacatcaatc gatctgatgg aacgtgcagc aaccgtatta acaaaagcca
     6961 tcacagacag atggaatacg gaaacgccgg tcactatctt tgccggaccg gggaataatg
     7021 gtggagacgc tctcgccgta gcccgcatga tggctgaaaa aggatataaa atcgaggtat
     7081 ttctcttcaa cacgaaagga gaactttcac ccgactgcca gaccaataaa gaactggtag
     7141 aaatgatgga agaagtaaaa ttccacgaaa tcagtaccca attcgtacct cccgccctga
     7201 cgcccgacca tctggtaatc gacggattat tcggttcagg cctgaacaaa ccgttaagcg
     7261 gcggattcgc tgccgtagtg aaatacatca attcctcccc tgctatggta gtagccatcg
     7321 acattccttc cggactgatg ggagaagaaa atacattcaa cgtaaaagct aatattatcc
     7381 gcgccgacgt aactttcagt ctgcaactgc cgaagctcgc ctttcttttc gcagagaaca
     7441 ctgaatttgt cggagaatgg gaagtgctgg atatccaatt aagcgaagac ggtattgaag
     7501 agatggagac taactacgaa atgttggaaa tagaagaaat ccgttcactc atcaagccac
     7561 gcaaacagtt tgcccacaag gggaacttcg gccatgcact attgattgcc ggttcaaaag
     7621 gaatggcagg agcctctgtt ctcgctgccc gcgcctgcct ccgttcggga gtagggctgc
     7681 tgactgttca tgcgccaatg tgcaacaacg acatcttgca gacctccata cccgaagcaa
     7741 tcgtagaaac cgacatcaac gaaacctgtt ttgccgtacc taccgacacg gacgactatc
     7801 aagcagtcgg catcggcccg ggactgggac gaaacgagga aacggaagct gccttattgg
     7861 aacaactgga acactgcctg actcctgttg tagtagatgc cgacgctctt aatatcctcg
     7921 ccaaccaccg tcatgccctt acccatctgc cgaagggttc catcctcacc ccgcatccaa
     7981 aagaactgga acgtctgacc ggcaaatgcc aggactctta cgaacgtctg atgaaggctt
     8041 gcgaactggc ccgtgccgcc catgtccaca ttattttaaa aggagcctac tccgccatca
     8101 tcacccccga aggtaaatgt ttcttcaacc caaccggaaa tccgggaatg gcaaccggag
     8161 gtagcggtga cgtactgacc ggagtaatcc tggcgctgct tgcccaaggt tatcccaccg
     8221 aagaagccgc taaaatcggc acttacattc acggattggc gggcgatgtc gctcaaaaga
     8281 agcaaggaat gatcggaatg atcgcaagcg atattatcac ctgtctgccg acagcatggc
     8341 gacttgtaag cgaataaaag ttaagaactt acagtttttt caataacttc attaactttg
     8401 ttttcaaaac cagttaaaaa gaaccgaata tgaaaaagtt gattatagca gcaggactac
     8461 ttatgacaac gtccgcctat gcacaaaccg aagtactgac aggggttacc cgaggaaaag
     8521 actatggagt ggtttacagt cttcccaaaa cccaaataga acttgaaata aaagccaaca
     8581 aagtcaacta tactccggga gaattcagca aatatgctga tcgttacctg cgactgacca
     8641 acgtctccgc cgaccctgaa gagtactggg aactgactag cgtaaaagtg aaatccgtag
     8701 gtgtgcccaa cagcgaaacg acgtatttcg taaaattgaa ggataagaca gtagcaccgc
     8761 tcatggaact gacagaggat ggcattgtga aaacgatcaa tgttccttac agcaacagca
     8821 gtgtaggcaa aaaagccgct cccgctccca cagtcctcca aaagaaagca aatcctcgtg
     8881 aattcctgac cgaagagatt ctgatggcta gctctaccgc caagatggcc gaactggtgg
     8941 ctaaagaaat ctataacatc cgcgaaagca aaaatgcctt attgcgcgga caggctgaca
     9001 atatgccttc agacggagca cagcttaaga ttatgctcga caatctgaat gcacaggaag
     9061 aagccatgac gcaaatgttc tccggcacct gcaacaagga agagagaaca ttcactgtcc
     9121 gccttacccc tgacaaggaa ttcaacaatg aagttgcttt ccgcttctcg aagaagttag
     9181 gtgtagttgc caacaatgat ttggcaggaa ctccgtttta tatcagtctg aaagacctga
     9241 aatcggtcaa gataccacag gaagatggta agaagaagaa agatttggat ggaatcgcct
     9301 acaacgtacc cggacaagct atggttacat tgaccgacgg caaaaagaaa ctttacgaag
     9361 gtgaacttcc tattactcaa tttggtgtga tagaatatct ggctccggtt ttgttcaaca
     9421 agaattctac catcaaagtt tattttgatc cgaatacggg aggattgctc aaagtggaca
     9481 gagaagaagg gaaatagaaa aacgagaaag tgaacttcta aaaaacaaag aatatggttg
     9541 gtgaaggaca tgcattcgac atgatacgcc gaataaaaga gggacgggaa gcttcccgcc
     9601 tacgtcgtga acgtgctaac gacaagttga agcatttaaa ccgtgcaaac gaaccttatc
     9661 cactacccaa taccactccc gaagaaatgg aacgtatcat ccacgactcg gagaaaaaga
     9721 aagagaaaga cagcaattat tttgtttggg gaacgcttat tatcatggga gtcctgatag
     9781 caattgccgt catactttgg gctgtattta tcaaataaat aataataaat tcaccacaga
     9841 ggacacggag gacacagagg tttaatcttt tttattcact atagagtaac acagagtctc
     9901 acgtattgag aatcgtattt atcgctctgt tttacttgcg gaaagagaga gaagaactct
     9961 gtgtcctccg tgtcctctgt ggtgaaatat aaattcctat ttatgcgact ggtatcacca
    10021 gttttataaa tccatctttc tgcatttgag aaagataagc cgatacacgc gactcgtagc
    10081 cctcttcatt ttgaaaatgg tctgcgagtt tttctataat ctcacgaaca ttgcgttttc
    10141 catctatcag ttcccataca gccgtaccgt gttcttccaa tttcacatga agttctttcg
    10201 acattccttt cggcacaagg aagcgttgca tccacggata tttaaaacgg ggaaaggaga
    10261 gcacaattgt ctccccttcc ctttctgctg taatatgttc actgcgacag ggaatgacct
    10321 ctaacaggtt gattttctct ttggcagcca tacttcttat tttttatttc agagtattca
    10381 tactgatacc cttttgttta caccttgata caaaattcct ttgttacttt aggtattgaa
    10441 tttcccagtt acttttggat attcgcctct tccagaccgt atcccttctt cttgttctct
    10501 gccttcaaca tcaaagccac aatcagagca agtacaccaa agagagcaaa aatagtcatc
    10561 ggcaacgtgt agtcataagt ctgtgcaccg tctactaccg gacctttgca ataagtattc
    10621 aacacccatc cgatcaacaa aggaacaccc atcaatcccc agttctgtac ccagaaaatc
    10681 aatgcgtatg cggtacccaa ctgtttttcc ggaataatct tcggaacaga cggccacata
    10741 gctgaaggca ccaacgagaa ggcaaatccc aatataatca tgatgatagt agcaaaccac
    10801 catatattca gtataggcag agcaaacatc gtatgcacaa aaataagcat cactgatccg
    10861 attatcatca atgtggctcc cttaccgata cggtcataaa gcgaaccgaa caacggagtc
    10921 aggataatcg caccaatcgg caacaatccg ggaatcgttc ccgccaactt cggatctacg
    10981 ttatatttct gcaccatcaa gtcggcagca tacttgataa aggggaatac agccgagtag
    11041 aacaatacac atagtaatgc aatcaaccag aatcctttat tggtaataat atacacaata
    11101 tctttcatac ggaacggttc ttccggttcc aatccctctg catccaaaga agcatccaac
    11161 ttcttatcat agaaagtata aaggaaaaaa gcaatcgtac ccacgcacaa cataatcaga
    11221 caaaacaaaa tcggagcagg aatatttgta tggaatgtgc cactctcatc cgtagatccg
    11281 aaaaagtctg ccaaaggaac tgtcaatacc atcgccagag ttgttccgat acgtgccgta
    11341 gccatttcaa gtcccatagc caatgccatt tccttgccct tgaaccattt cactataatc
    11401 ttggaaacag tgataccagc aatctccaca cctacaccaa agatagcata tcccaatgca
    11461 gccaacgtca cctgtgtttt gaatccgaag agcatggcac cttccggaaa agtagtagaa
    11521 atcgcatagt atttcaatcc acaaccaaac accatcaata agcaagcccc cattccggtg
    11581 aaacgaactc ccatcttatc caaaatgata ccaccgaaga tcagcatcaa taggaataca
    11641 ttaaaccacc cgtaagcact tgtgaagaaa ccataatcaa gactgtccca tagtagttct
    11701 ttctcaagca tgggttttag aggagacatt acgtcggtga ggaaatagcc gcatagcata
    11761 gtaaatgcga ccaatgctag aacactccat cggagtacgg cggagtcatt caatttctgt
    11821 ttcaaatgtt ctgtcattgt tatatttaaa aaagtagtta ataatcttat acagccaaca
    11881 aaggtagtta aatctcgttt gtttctatca caaagagatt gtttttacaa gaaaaagtta
    11941 agtgcggatt acactgacca cgcggaacat tgaaaatccg tgtaatctgc gtaatccgca
    12001 cttaaatatc aaagaaatgc agcatccgtc tgcaccttcc cattaatggt tttaccccaa
    12061 agtcttactt gacgacggag tgaattactc tgctgcagga gcaggagttt cagtagccgg
    12121 tgccggagtt tctgtagcag gtgcattggt agcaggagct tcagtttgcg gcgcagccgt
    12181 acctgcgggt aagttatacg ggttagtctg ttgttctttc tgtgcctgtt ccaacactgc
    12241 gtctttagca acagcagagc gaggaactac ataagcagta gcaatgctca ttacaaccat
    12301 aaagatggcc aggccccatg ttgctttttc cagaaagtct gtagtcttgc gcacgcccat
    12361 gatggcgtta gatgaagaga aaccagaagc aagtccgcct ccttttgagt tctgaatcag
    12421 cacgatgaaa cacatcaaca aggctgcaat aaccattaag ataacgaata ataagtacat
    12481 ttttagttat tttgaattag cgttaataat caatttctcc aaaaatctga tttggtctgc
    12541 aaagtaagca tttttttttg gatatttcaa gcttaatttt ttaattattt caagagcttt
    12601 tgaatatcgt tgctgtttaa catagatttt tgccaaagtt tccgtaaaac agctgtcatc
    12661 ttcctcttct tcctttatcg tttcttcttc ggtaagttcg tccgaagagg ttggcgaaga
    12721 tggcatttct tctcttaaag gtttcatgca gaggggagag tcgctctcgc tcttttctat
    12781 aaaatcgtca atcagttcga agcctttgag tttgggcgtt tcttcagccg gctgttccgt
    12841 ggccggagtc tcctccaaaa ggaaagaggt gtaatccatc gaatagtcga aactggtccg
    12901 ggcagtcacc tcttcgggta ctgtggacaa gaaagcgtcg atcaatgcta atgtgcggtc
    12961 tacggacggt tcgtctttca gcacctccgt gagaggtact ccctttttcc gcgcctgcac
    13021 atcatagcgg tcaccttcaa tcaaccggaa caactgccgt ctgtctgcaa tgtaaagaac
    13081 tgctttccgc agttctccac cgaaactaat atcatggaga atatacagat tcttcagata
    13141 caacagacga agtgactgaa aatacggata cctcgcaaga agattgcgca gttcgtacaa
    13201 agtatcccta ttcagcgtct cgggatgctg aatccattgt tgaaagttaa cagaagtcat
    13261 ttatattacc agtttgctac agttgcatta aaaatttggt cggtgatctc tttagacatt
    13321 tcagcaatca atccgtcctg tacggcagtc aacaactggg tagagtcgta ggtacggaac
    13381 gcagaaaact gttgttcaaa gtcttcggca tgattggtgt tgttgacaaa acgcacattg
    13441 acggtgatag tcaacttcgt ctccgaagaa taaccgtcgg cagatactgc ctggttgtac
    13501 tgattgtacc ctgtgatttc tccgtcaatc tgcaagtcgg cattttgact cggcttgagc
    13561 agttgcagac gggtctgccg gatgaagata tctttcaggt cctcattgaa tttggttgcc
    13621 aacggagcat atacatactc cgacttgatc gggaagtcgg ctatcgaaat ggtctttacc
    13681 ttatcataat tgatagacga tccgttaaac ttataggaaa cagtgcacgc aatgactacc
    13741 aacggcaagc cgaacagtag caaagggcgt attattttct taatccaatt catattcttt
    13801 tatttttcta taaagtgtac gctcggaaat attcaagtcc ttggccgcac tcttccgctt
    13861 tccatgatgc ctctcaagtg ccttgcgtat catttctttc tccacttcgt ccagtgacaa
    13921 aggagattct tctacatatt cttccgtgtc ttgtatgtca tcgtcatcct tgcaaaccgt
    13981 aggctgcatg gtgtgaatga tagcaggtac cgaaggttga tgtgccgtca ctaccggagt
    14041 agtaaccacc gttcccattt gccctacctg ccccacctgt ccggcacgtt ccgccatcag
    14101 gttgtgcacc atcttcttca gctccgccac ttcctggcgc atatcgaaca gaacagaata
    14161 aagaatctcc cgttcgctct caaagccttt actctcacgc gttcccatca gcgcgggaag
    14221 acgttgcgta ttttgtgcag gaagataatt ctgcaagata gcagcagaga tctccctgtt
    14281 ggtttcaatg atagatattt gctcggtgat gttcttcaac tgacgaacgt tgccgggcca
    14341 cgggtaagcc aataactctt tcttcgcatc ctccgtcaac tggatagcag gcatccggta
    14401 tttctctgca aagtctgcgg aaaacttacg gaacaacaaa agtacatcgt caccacgttc
    14461 acgcaaaggc ggtatttgga taggcaccgt attcaaccgg taatataaat cttcacggaa
    14521 acgtccttct gcaatcgctt gtgtcagatt gacattggta gctgccacaa tacgaacatc
    14581 cgtcttttgc actttggacg aacctacttt tataaactcg ccactctcca acacacggag
    14641 caaacgcgcc tgggtaggca tcggcaactc ccctacttca tcaaggaaaa tagtaccacc
    14701 gtcggcttcg ccaaaatacc ctttccgttc gccaatcgca ccggtaaacg cacccttctc
    14761 atgcccgaac agttcggaat caatcgtgcc ctccggaata gcaccacagt tgacagcaat
    14821 atactgtcca tgcttcctcc ggctatattg atgaataatc tgcggaaaac tttcttttcc
    14881 gactccactt tctccggtaa tcagcacaga caaatcggta ggagctacct gaatggcaac
    14941 atctatggcg cgcgacaatg cttcggtatt acctataata ccgaaacgtt gtttcacttg
    15001 ttgtatctct gctctcgtca tcactcgttt ttaatcttcg tctactgtat ccagcttcag
    15061 tttatcacta tcgtcacgtt tctcgtaata ctgtttacgc aacggattgg cacgagccac
    15121 tttttcccgc tgacgattac ggaacacatc gatggcaaca tagattgcct gacggaaaga
    15181 atcttcacaa gccaatccct tgcctgcaat atcg
//
