LOCUS       c00031_gnlPro..        16445 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CKJHMDJL_107.
ACCESSION   c00031_gnlPro..
VERSION     c00031_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:26:30
            Original ID  :: gnl|Prokka|CKJHMDJL_107
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16445
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..132)
                     /locus_tag="ctg31_1"
                     /transl_table=11
                     /translation="MKTTEVNKELIGKRCECIFTGLMVTGVIEDTEENEHTIEVKVRF"
     protocluster    1..16445
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3486:6445]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3487..6445
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16445
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16445
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(144..362)
                     /locus_tag="ctg31_2"
                     /transl_table=11
                     /translation="MQSLNKNGVSITQTPGEEKYVKCCLGAFRGQIYFQYDYRHFDGEL
                     FSTVAKTLAECRRRRDGWIAKKEQSNK"
     CDS             complement(440..973)
                     /locus_tag="ctg31_3"
                     /transl_table=11
                     /translation="MEATTLSAASVYVGTYAKYNNGSLSGAWLNLSDYSDKEEFYEACR
                     ELHKDEEDVEYMFQDWENVPEGLIGESWISENFFSLRDAVEDLSDTEQEAFFVWCNYKS
                     HDLGEEDADDLVRDFRDEYQGEYDDEEDFAYEIIEECYDLPEFAKTYFDYEKFARDLFM
                     CDYWFDDGFVFRAA"
     CDS             complement(1645..2874)
                     /locus_tag="ctg31_4"
                     /transl_table=11
                     /translation="MKSTFKVLFYLKKGSEKKNGEVMIMARITIDGKQCQFSTKQSIQP
                     DNWSIAAGKAKGRDAGRINALLDDIRSSLNTIYHEMQRRDNYVTAEKVKNEFLGHSESH
                     ETILSLFQKHNDDVKQLVGISKTIATYRKYEVTRRHLAEFIRSKYNVSDISIKEITPMF
                     ITDFELYLRTACKCGYNTTAKFMQFFKRIIIIARNNGILVGDPFASYKIRLEKVDRGYL
                     TEDEIKIILKKKMVSERLEHVRDLFVFSCFCGLAYSDVANLRQENIQKSFDGNLWIITK
                     RVKTNTDVNVPLLDIPKMILKKYKGKLPDGKILPVISNQKLNAYLKEIADICGIKKNLT
                     FHLARHTFATTTTLSKGVPIETVSKMLGHTNIETTQIYARITNSKIGSDMQGLDKKFVG
                     IEKIYKEVAM"
     CDS             3487..5715
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_5"
                     /sec_met_domain="Gly_radical (E-value: 3.1e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1167.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5720..6445
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_6"
                     /sec_met_domain="Radical_SAM (E-value: 4.2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFQTVQVN"
     CDS             complement(6677..7939)
                     /locus_tag="ctg31_7"
                     /transl_table=11
                     /translation="MMKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYP
                     YRRWAVAAAAVVLVLTTVVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAV
                     SEPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLVEKRPEAVTEEKRSEPQQEAIAAIE
                     KKESATAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENF
                     APRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVR
                     KSLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVS
                     AGGMVEKCVYGKLADDKVNVKPLQFSVVGAVGAQFNATDHVGLYVEPGVSYFFDDGSKV
                     QTIRKERPCNFNLQAGLRFTY"
     CDS             complement(7991..8539)
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             8727..9479
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGKEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(9584..10510)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.4; E-value: 35)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg31_10"
                     /sec_met_domain="LysR_substrate (E-value: 1.1e-46,
                     bitscore: 151.2, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.7e-18, bitscore: 57.2,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIQQLEYILAVDQFRHFAKAAEYCRVTQPTLSAMIQKLEDELGV
                     KLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKEIISEEQHSLSGTFRLAVLPTIAPY
                     LLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTGEADAAIIASMLDDAALTEETLFYE
                     QFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGHCFRDQLVRFCQMEAVKISQMAYRL
                     GSMETFMHMVESGKGITFIPELAVMQLSEEQRELVRPFAIPRPTRQIVLVTRKDFIRTS
                     LLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             10652..11125
                     /locus_tag="ctg31_11"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(11229..12227)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_12"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.9e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(12282..13550)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_13"
                     /sec_met_domain="MFS_1 (E-value: 5.5e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(13800..14117)
                     /locus_tag="ctg31_14"
                     /transl_table=11
                     /translation="VANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRK
                     EGETEWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVK
                     Q"
     CDS             complement(14121..14813)
                     /locus_tag="ctg31_15"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSIADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFT"
     CDS             complement(14836..15972)
                     /locus_tag="ctg31_16"
                     /transl_table=11
                     /translation="MKRITIKQYLLACFVLPMILAGCNDADYQVIDNAIYLNEASENGS
                     AKVTVDPENVTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTY
                     DKEIKIAAGDVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDK
                     PLIQSVPFMNTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVY
                     IRFGDAMIPYNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQ
                     TKGGPVRFDKMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGY
                     WKMDEGKGNAFVDCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 gaaacgaact tttacctcta tggtgtgttc gttttcttct gtgtcctcga taacgcccgt
       61 taccattaag cccgtaaaaa tacactcgca acgcttgccg ataagctcct tgtttacttc
      121 tgtcgttttc atatccctaa aatttactta ttactctgtt cttttttcgc tatccacccg
      181 tcacgcctgc ggcggcactc tgccagcgtt ttggctaccg tgctgaaaag ttcgccgtca
      241 aagtggcggt agtcatattg aaaataaatc tgtcccctga atgcgcctaa gcaacatttc
      301 acgtattttt cttctcccgg tgtttgggtg atgcttaccc cgtttttgtt aagtgactgc
      361 atgatgtctt atttttttac ggttataaac ttggttgttt ttaacgggca gggctttgac
      421 accccgcccg gattggttgt tatgccgcac ggaacacaaa gccgtcatca aaccagtaat
      481 cgcacatgaa caggtcacgg gcaaactttt cataatcgaa ataggtcttt gcgaactccg
      541 gcaggtcgta acattcttct ataatttcat aggcgaaatc ttcttcatcg tcatattccc
      601 cttgatattc atcccggaaa tcacgtacaa ggtcgtccgc atcttcctcg cctaaatcat
      661 ggcttttata gttgcaccac acgaaaaagg cttcctgctc ggtgtcgctc aaatcctcca
      721 ccgcatcacg cagggaaaag aaattttcag aaatccagct ttcgccgatt aagccctccg
      781 gcacgttctc ccagtcctga aacatatatt ccacatcttc ctcgtccttg tgaagttccc
      841 ggcaggcttc gtaaaattct tccttgtccg aataatccga aaggttgagc catgcgccgg
      901 acaatgaacc gttgttgtac ttggcgtaag tgcctacata aacgcttgct gctgataatg
      961 tcgttgcttc catattgctg taatttttaa gtttttaatt ttatgcggat tcgagaggtg
     1021 agggagttga agtttcactg aacttttttc ctgtttcccg taaatccgac ttttttttta
     1081 tgcgtcttcc ggtcgggtcg gtcgttttcg tttcacatag gcgtaaaagg gtagtgttta
     1141 gagtttgcaa agttttgggc aaaaaatacc tcgcaaggca gggaagattt tttcgccaaa
     1201 ccggaacggc tcgaccttgc aaaatcgtga agaacacgta actacctttg cctattgaaa
     1261 tgattaaaac gactgtcccg gctgggggac tgcgtaagag gaagatttac agatagggaa
     1321 actggggaaa agtgcctgtt ctctttcatc ttttagggaa cactccatgc gggtgggaaa
     1381 ggcaagggta tggcaagttt accttgcggt acgcttgtgc gggtttccaa cggctctttt
     1441 cacgaaatac agtcagccat gccacgcacg gctggcgttt cggggaatgt gccagtggga
     1501 aaaggatata aaaaatgcgg gtagtcggtg gactgcccgc aaggtgaaag aatgtacttt
     1561 attgggatat agtttgttag gtggaatttc gttaccgaaa tcgttacctg ttctgttacc
     1621 aacagtatat aggtaactaa aaactcacat ggcgacttcc ttgtaaattt tctcgatgcc
     1681 gacaaacttc ttgtcaagcc cctgcatatc gctgcctatc ttgctgttgg tgatgcgggc
     1741 gtaaatttgc gtagtttcta tatttgtgtg tcccagcatc ttggacaccg tttcaatggg
     1801 tacgcccttt gacagcgtgg tggtcgtggc gaacgtgtgt cgggcaaggt ggaatgtcag
     1861 gttcttttta ataccgcaaa tatcggcaat ctctttcaag taggcgttta gcttctgatt
     1921 gctgattacg ggaagtatct tgccgtccgg caacttgccc ttgtacttct tcaaaatcat
     1981 cttaggaata tccagcaggg gaacatttac gtccgtgttg gtctttaccc gcttggtgat
     2041 tatccaaagg ttgccgtcaa aggacttttg gatattctcc tgccgcaagt tggcaacatc
     2101 gctgtaagcc aaaccgcaga aacaggaaaa gacgaacaag tccctgacgt gttccagccg
     2161 ttcggaaacc attttctttt taaggatgat ttttatctcg tcctccgtca agtagcccct
     2221 atccactttt tccagccgaa ttttgtagct ggcgaacggg tcacccacca gtatgccgtt
     2281 gttgcgggca atgatgatga tgcgcttgaa gaactgcatg aacttggcgg tggtgttgta
     2341 accgcacttg caggcggtac gcaaatacaa ctcaaaatcg gtaatgaaca ttggagtaat
     2401 ttccttaatg gatatgtccg atacgttgta cttgctgcgg atgaactcgg caaggtggcg
     2461 gcgggtcact tcatacttgc ggtaggtcgc tatcgtcttg gatatgccca caagctgctt
     2521 cacatcgtca ttgtgctttt ggaacaatga aaggattgtt tcgtggctct cgctgtgtcc
     2581 caagaactcg ttcttcactt tctcggcggt cacgtagttg tcacgccgct gcatttcgtg
     2641 gtaaatggtg ttcagggaag aacgtatgtc gtccagcagg gcgtttattc ttccggcatc
     2701 cctgcctttg gctttgcctg cggcaatgct ccagttatcg ggctggatgc tctgtttcgt
     2761 actgaactgg cactgtttgc cgtcaatggt gatacgtgcc ataatcatta cctcgccgtt
     2821 tttcttttca gaacctttct tcaaataaaa aagaaccttg aatgtcgatt tcataactca
     2881 ctttttttag ttgcaaaatt actttttacc tctcgtttct gagttatgca gactatggac
     2941 taatcaagtc attatcaggt catttatgga caaatcgtta ccgtttttgt ccggtgggga
     3001 ataggtaacg atttagtaac gaaactttgt cttttaccgt acttttgaag tcttggaagc
     3061 aggactttcg ggcaataaaa aaagccacaa atcattgatt tgtagctttt tgtccgttta
     3121 ctgtccattt ctgtccagta agttcagcgg agagacaggg attcgaaccc cgggtacctc
     3181 gcagtacaac ggttttcaag accgccgcaa tcgaccactc tgccacctct ccagaactac
     3241 ggttaagtag tgcttttctc ttaaagcgct gcaaaggtac gaatcatttt ttaacttgca
     3301 aattattccg caaaaaaata ttagaaaagt atatttggaa gtaataactg ctatctggct
     3361 tctccccata aataggtatt tttatgctat tcaacataaa ataggaccct tttatatacc
     3421 taaaccgaaa aaaggttgta aatttgcgcg ctctaaagga taactaacca ctaactgatt
     3481 aattttatgg aactgaataa gacctttaaa gatggacttt ggagcaaaga aatcaatgta
     3541 agggatttcg ttagtaataa catcactcct tatgaagggg atgcttcttt cctgcaagga
     3601 cctaccgaac gcaccaaagc tgtctggaat cactgtctca aagctcttga agaagagaga
     3661 aacaataatg gtattcgtgc actcgactac acaactgtat ctactataac ctctcaccct
     3721 gccggctaca tcgataaaga gaacgaactg atcgtcggac tacagaccga tcaggtgtta
     3781 aaacgtgcca tcaaaccgtt tggcggaatc aatgtggtta tgaaagcttg ccgtgaaaac
     3841 ggagtggaag tagatgacag agttaaggat atcttcactc actatcgcaa gactcataat
     3901 gatggggtat tcgatgtgta taccgaagaa attcgttcgt tccgttcatt gggattcctt
     3961 accggacttc ccgacaacta tgcacgcgga cgtatcatcg gtgattatcg ccgcctggct
     4021 ctctatggtc ttgaccgtct gatagaagct aaaaaagaag atctgcataa tctgacaggt
     4081 cctatgactg aagcccgcat tcgtcttcgc gaagaagtag ccgagcaaat caaggccctg
     4141 aaagagatta aagtattggg cgaatattat ggtttggatc tgagccgacc ggcatatacc
     4201 gcacaggaag ctgtacaatg ggtgtatatg gcttatctgg ctgccgtaaa agagcaggat
     4261 ggtgctgcca tgtcactggg taatgtatct tcattcctcg acatctatct tgaatatgaa
     4321 ttaagccagg gtacgataac cgaaacattc gctcaggaac tgatcgacca attcgttatc
     4381 aaactccgta tggtacgcca cttgcgtatg cagtcgtaca acgatatttt tgcgggtgat
     4441 cccacatggg tgaccgaatc tatcggtgga cgtttcaatg acggacgtac caaagttact
     4501 aaaacttctt tccgcttctt gcagacactt tataacttag gcccgtcacc ggaacctaac
     4561 atgactgtac tatggagccc tgagttaccc gaaggtttca aagcattctg tgcacaagta
     4621 tctatcgaca cttcttccgt acaatacgaa aacgacgacc taatgcgtga agtccgtcaa
     4681 tcggatgact acggaatcgc ttgttgtgtt tcatatcagg aaatcggaaa gcagattcaa
     4741 ttcttcggcg cacgtgccaa ccttgccaaa gccctgctac tggctatcaa cggaggacgt
     4801 tgcgaaaata caggtacagt tatggtaaaa gacatccctg tattgaccgg tgaaacactg
     4861 aagttcgaag aagtaatggc caactataag aaagtattga tacaaattgc acgtgtatac
     4921 aacgaagcaa tgaatatcat acattacatg cacgataagt attactacga aaaggcgcag
     4981 atggctttcg tggatactga tccccgcatt aacctcgctt atggtgtagc cggactctca
     5041 atcgccatcg attcactgtc cgccatcaaa tatgcacatg tgaaagcccg tcgcaacgac
     5101 atcggactga cggagggatt cgatatcgaa ggtgctttcc cttgtttcgg taatgacgat
     5161 gaccgtgtag accacctggg tgtggacctg gtatatttct ttagcgaaga attaaagaaa
     5221 ctccccgtat ataagaatgc ccgtcctacc ctttcgctgc tgactatcac ttcgaacgta
     5281 atgtatggca agaagaccgg tgccactcct gacggacgcg ccaaaggcat tgcctttgct
     5341 cccggtgcca accccatgca cggacgtgat aaaaatggtg caatcgcctc actgagttct
     5401 gtagccaagt tgcgttatcg cgactcacag gatggtatca gcaatacatt ctcaatcgtt
     5461 cccaaatcat tgggagcaac acaagaagac cgtatcgaca atctggtgac catgatggac
     5521 ggatatttta caaaaggcgc acaccacctg aacgtaaacg tgctgaaccg ggaaatgttg
     5581 caggatgcga tggaacatcc cgaaaagtat ccgcaactga ctatccgtgt ctcaggatat
     5641 gccgttaatt tcgtgaaatt gagccgcgaa catcagttgg aagtaatcag ccgcagtttc
     5701 cacgaaagaa tgtaattgaa tgataaacgt acactcatac gagtcaatgg gaacattcga
     5761 cgggccgggt ctccggctcg tcgttttcct tcaagggtgt aacttccgtt gcctctattg
     5821 tgccaatccg gacacaattg aagccaaagg agggacagca accgaccctg aggaaatagt
     5881 tcgcatggcc gtcagtcaga aagctttctt cggtaaaaag ggaggtatca ccttttccgg
     5941 cggagagcct acttttcaag caaaatcgct tatcccactt tttaaaagac taaaggaagc
     6001 aggaatccat atttgccttg ataccaatgg cgggctatgg aacaatgatg tagaggaact
     6061 attggaattg actgatctgg ttttattaga tatcaaagaa tttaatccgg aacatcatca
     6121 gtctttaacc ggaagaagca acgagcagac cctgaaaacc gcagcctggc ttgaaaccaa
     6181 tcataaacca ttctggttgc gatacgtatt agtgcccggc tacagtgact tcgaagacga
     6241 tatccggcag ctgggagagc atcttggaac gtaccagatg attcagcgtg tagaaatatt
     6301 gccttaccac accttgggtg ttcacaaata tgaagcaatg aacaaagaat atatgctgaa
     6361 aggagtgaaa gagaatactc cagagcagat agaaaaggct gagaaactat tcaggcaata
     6421 tttccagacc gtacaagtaa attgacttat ataagtgtcg aaattcgtat tcaccacaga
     6481 ttacacgaat ttacacaaat aaagatcatt ggcaatcaat agattaagtt cattctgcgg
     6541 tgaattatga cgactgcact tatttataat tttgtaagtc acgatataaa agtctccctg
     6601 ttcttgcctt aattcattac aatacaaggc aagaacaggg agataatgta accggcatat
     6661 tttttgccat cctactttaa taagtgaatc gcaatcctgc ctgcaagtta aagttacaag
     6721 gcctttcttt tcggatggtt tgtactttgg agccatcatc aaagaaatac gaaactcccg
     6781 gttccacata taggccgaca tgatctgtcg cattgaattg cgctcccacg gcaccgacta
     6841 cagaaaattg caaaggcttc acattcacct tatcatccgc caactttcca taaacacact
     6901 tttcaaccat tcctccggca gatacataga gtgtaaaata tttcttttcc agaaaattcc
     6961 agtttccacg tacaggaata cctatataat gcaatttctg actctgcatc ttggtatccc
     7021 cctgccgttt gatgtcagaa gacaacaacg tataagtcaa tcccgtctct acagagaaac
     7081 ctttgggaag agacttacgt acagacagtc cgaagctaac cggctgatga tgttcataat
     7141 ccaccacggc agttgtattg gacttcaggt aagggactcc ttcttcaaat ataacttcct
     7201 gatcggcagg aatactcaca gctccattca tgatcgtcat caagtcgacc ctgttagtca
     7261 tcggacgggg cgcaaaattt tcggaaccat ttgtcggaag tccacctcca ttaccgatac
     7321 ccactcccat cgaccattta ccaccacgtt tagcagaaga gtctccgata ggcaactgat
     7381 acttgtcttt accggacggt cgccgcgctt ctttcctctt tggaggctgc gccgtcgcac
     7441 tttctttttt ctcgattgca gcaattgctt cctgttgcgg ctcagatctc ttttcctccg
     7501 tcactgcctc cggtcgcttc tctaccaggg aggatacctc cggaacaatc accggatcag
     7561 tattctttgc caaatagccc gaaacagggt taatactcgt cgttcctacc ggcttaactg
     7621 gttcggatac agctacctgt acatccggca aggcaggttc cggcaataca tccgggttga
     7681 cagccagtga aggagccgtt gcataacgga tttcatcagc taccggacta ttcagaaaat
     7741 acaaactgac aacagtcgtt agcaccaata ccacagctgc cgcagcaacc gcccaccggc
     7801 gatacggata tattcgtttt tcggttacag gcatcagttc cctttccagt cgttcccaac
     7861 cggaagcagg catcggctcc gaataatctt cgagcttatc cttgaatgct ttaatccatt
     7921 tttcgtcttc tttcatcatt ctatttcatt tttgaaatcc aagattcacc tcagtatctg
     7981 taaatacatg tcaaccattg gtcaccaacc attctttcac tttctttgcc aatacacttt
     8041 ttgcgcgaaa aagctgtgag gcagaagatt tttcattaat ccccaacatc tgtgcgattt
     8101 ccttgtgcga cttatcttca aaggtgtata aattgaatac ggtacgatat ccggcgggga
     8161 gttcattaat aaattgcatc agcactttct gtggtattgc ttcaacagcc gaagcatccg
     8221 gttcttcata cgtttcggga acttcatcca gtgccgtggt ctggttcatc acgtcgttct
     8281 ttcttaagaa ctgtaaagcc gtattcacca ttacacgctc catccatgct ctcagagagc
     8341 cttcaccccg ccaggtaaac ttgtcgaagg agtcgaaaat cttcaggaaa ccgtcgtgta
     8401 ccaagtcttg tgccatgtcc ctgtctccgg cataacgaag acagacacca agcatgcgcc
     8461 ctgcgtactg ctcataaagt tctttgcggg cacgattatc tccctgcctg caacgttccg
     8521 acagctctaa ttcattcatt ctcctaaaca cgtgtttacc ttataaatgc agcaaagata
     8581 gaaatactgc acagagagaa caactctttt atcacttttg tttctttaac attttaggat
     8641 gcaatatttc atcacttcct gcattttctc aatacaataa agaataaatc tcaatggata
     8701 aataggataa aaccaacaag aaacttatga agaaatttaa tttaataact tttgccgtca
     8761 tcctgatgtt attgcccatt ttacagtcat gtctggacga tgccaacaac gacgagtggg
     8821 tcacttgtcc tccgggtgga atattggcca tcggcacaat gaagattccc aatgcggaca
     8881 ctccaaggga ctttttcatt gcgttggaca atggagacaa tgtacttccg gcagatacgg
     8941 ccgatatacg caacaggaaa tacactgttg cagaaggtca aagagtcttc gttggctatc
     9001 tgcagatggg aaaagagaag cccggatatg agaacggtaa aatattcacg atagaagata
     9061 tattgacgaa agagatcatc ccactgacgg aagctacagc agacagcatt ggagacgacc
     9121 gtatcaacgt cacagcgcat gcacttacga aagattatct gaccatcgaa tatcaatatc
     9181 tgggcagcat gaatgaaaat aaaaaacaca tgctgaactt ggtacaaaac gaaataacag
     9241 gtcccataaa agatgacgga tatatctatc tggagttccg gcataatgcc tttaatgact
     9301 cccccaatca attgggttcg agccttgttt ctttcaagct ggatagtata gccgagcaat
     9361 tggcgacagc caaaggaata aaactccgtg tgaacaccat ttatgacaat atacagtatg
     9421 tcacaataga tatcaacgaa gacaaaaatt taaaaataaa atcatttcat tctcaataaa
     9481 acaacaagaa acacctacac aatcaggcaa aacgagtaat aattctgata cataaaagaa
     9541 ataaggcggc gatgtttgtg aaaatatcgc cgtcgttttt atattatacc agacactgaa
     9601 cggcctgcag ggtaagcatc tccttgggaa ccgccgcctg aatctcctct ttcaaaacct
     9661 gcagcagact ggtgcggatg aagtctttcc gggtcaccag gacaatctga cgggtaggcc
     9721 gcgggatagc aaacggacgg accagttctc tctgctcttc gctcaattgc atcactgcca
     9781 gttcgggaat aaacgtaatc cccttaccac tctccaccat atgcataaag gtttccatac
     9841 tacccagccg atacgccatt tggctgatct taaccgcttc catctgacaa aaacgaacca
     9901 actgatcgcg gaagcaatgc ccttcgtcaa gaagccaaag ccgttcccct gtcacatcgg
     9961 acgtacgaat cacatcgtgc ttgaacaacg gttccttctt tgagacatag cccaggaatt
    10021 gctcgtagaa taaggtctct tccgttaatg cggcatcatc cagcatgctg gcaatgatag
    10081 cagcatccgc ttcaccagtc agcagagcct tgcgaatgtc gggcgtcttc atctccatca
    10141 cccgtatatc aagatctggg tatttctcca tcagttgcgg aaagaaacgg ggcagaagat
    10201 aaggtgcaat cgtcggtaac actgccaatc ggaatgtacc cgacagggag tgctgttctt
    10261 cgctgatgat ctccttgaca cagataactt ccgaaagaat cttacgggcc tgttccagca
    10321 ctttcttacc aatggcagta gggcaaaccg gtgtcatgct acggtcgaac agtttcaccc
    10381 ccaattcgtc ttccagcttc tggatcattg cactcaaagt aggttgcgtc acccggcaat
    10441 actcggcagc tttagcaaaa tgccggaact ggtcgacagc cagaatatat tccaattgtt
    10501 gtatagtcat cgttctctga tttattaaag atatagaatc tatcaatgca aagatagaaa
    10561 ttttcagttt gacacgaatc attttgtgcc gtatctttgt tccagataaa aagaagaaat
    10621 atagtattaa ctcaaaaaaa acaatatcat tatgaagact ttaaattata cacatttgga
    10681 agaaaaagga gctaacacca tcgtactgtc attacagcaa ctgcttgccg attttcagat
    10741 tcattatgca aacctgagag gatttcactg gaacatcaaa ggacacggtt tcttcgtact
    10801 gcacagcaag tttgaagatt tatataacgg agccgccgaa aaggtggacg aaatagccga
    10861 acgtatactg atgctgggag gaactcccgc caataaatac agtgactatc tgaagatggc
    10921 gcagatcaag gaagtggacg gagtgaataa ggccgacgac gctctgaatc atattctcga
    10981 aacttacggg catctgattg cggaagaacg taaaatcctg tctctcgcct cttcacacaa
    11041 cgacgaagta acagtggcca tgatgagcga ctacctgaaa gaacaggaaa agatggtttg
    11101 gatgctgact gcatacaacg gataacagcc gaaagggtgt agccatctga ccgaaaaggt
    11161 gtagccatac aagcaaaagg gtgtagccat cccggcggga tagctacacc ctttctgttt
    11221 tattcgattc agatgatact tgtacgtttg gtaaattcaa taatctccgg aatgtatccg
    11281 aatgcgagcc cggtcactgt atccgcacac ccataataga tggcaatccg tccggtctcc
    11341 gaatcatgaa gcgccgcgca tgggaaacag acattaggca catcacccat acattcgtaa
    11401 tccttctgag gtgaaatcag ataaggcccc gaacggaatt ttactttcca gggctgatcg
    11461 atgtcaagca gtgccgaacc aaaactatac acaaaaccgt tgcaggaagc caatacacca
    11521 tgatagatca gtaaccagcc ttccgaggtt tcaatcggga taggccctgc accgatcttg
    11581 gtacactgcc aggcactgtc ttcgaacgga gccggcgaca taacatgacg atgacgtccc
    11641 cagaactcca tatcgggaga ctcgctatag aaaatatctc caaaaggagt atgcccatta
    11701 tcactcgggc ggctcaacat cgcaaaacga ccgtttatct tacgagggaa caaaactcca
    11761 ttccgattga aaggaataaa ggcattctcc aactggtgaa aagtaacaaa atcataggtg
    11821 taggccacac cgatagtagg accatgatag ccattacacc aggtcacata gtagcggtct
    11881 tcgataaagc aaacccgtgg gtcatatcca tagacccagg ttccaacctc agcatcatca
    11941 cattgaaact ttaacggttc ttcgttgata tcccaatgaa cagcatcctt gctgaatccc
    12001 acatgcaaac gcatgcgacg attagtatca tcacaacgga acacccctgc atagccatcc
    12061 ttaaacggaa ctacggcact gttgaatata ctgtttgaag tagggagcaa gtcgcgcgga
    12121 ataatcggat tggccgaaca acgccacact acatctttac atcctgccgg acgttcttcc
    12181 caaggcatag ccggcaaagc agcacctgca attttaattt cttccatgat tcgattaaat
    12241 taatattatg tatatatctt gtttatattg aaaatctctt tttatttctt ctttccgtcc
    12301 ggatatgtga aaggtaccag ccaagtcacg ataaaagccg gtatggtagc gataagtacc
    12361 cagataaaga aatcgcgata acccagccaa tcgctcaggt atccgctcat cattccggga
    12421 agcatcaccc ccagattcat aataccggta gcaaaagcat aatgtgccat ctgatgtttg
    12481 ccgggagcca cttgctgcat cataaagagc atcaatccga caaaaccaaa cccgtaaccc
    12541 aagtattcag acacaatggc cataccaata atccatagat cggaaggctg gtaaagggct
    12601 aacaggaaat ataccaagaa cggaatatta aaagcgcaac ataaagaaaa caaagtcttc
    12661 cgaagtccga aagccgaaat gtaataaccg gccaaaagcg aaccgagaat aaaagctccc
    12721 gctccgaacg taccatatac cagtccgata tcctgagtgc tgagtcccaa tccaccatcc
    12781 gcaaccgacg ctttcaggaa caacggtaca atcttgatgg catatccttc ggcaaaccgg
    12841 tacaaaatga taaagacaat gtagaaagca atatgttttt tttggaaaaa agagcggatg
    12901 acttcccaaa gcatattcaa tgcgtcactc atcgtattca cttcaccgga agctcctcct
    12961 cccgaaggca aaatccggat gtggtaaaga ccgatcagaa tcataatacc cgcacacatc
    13021 aacatgacaa tcatccaggc atgtaccact ccaaattcat ccttcagcat acctgccagc
    13081 caaaccaagc ctccgttggc aagtatctta gccagattat aaaaagctcc ctgccaaccg
    13141 atatacttgg cttgctgggt agcagtcagt tcagtcaggt atactccgtc acccgcaatg
    13201 tcatgagtcg caccactgag agcaatgatc cccatcagag cgatggcata acgaaaaaag
    13261 tcgggcagcg gcagcgaaag tgctaccaat gcaaatgcca gtccggtaat gatttccgta
    13321 gcgacaacaa agtatttttt cgttttaaac atttccagaa acggactcca taaaggcttc
    13381 aatgtccagg gaagcataat gagagaagtc cagaaagcaa tctgtgcatt cgacacttcc
    13441 atatcggaaa acataaggac agaaaccatc gaaagggcca caaacggcaa tcccatagca
    13501 aagtaaacag taggcaccca acatacaggg cttatcggct ttttattcat cagttagttt
    13561 tttataataa ttccatcggt taacaattcc agtaagcaaa gataggggat attaaaaaca
    13621 taacccaaga ttacgacaag aagttgcttt cattatttaa taatacaact cacccgggaa
    13681 aactactaac ctctatcacc ctttttttat taaactttat caatacaata cacgcaaaga
    13741 agcaccgaag actttcatcc ccgatgcctc tcgccccctt atctacaatc taaacacctc
    13801 tattgcttca catataaatt tatctcagca aacccggtat aattatccgg agtcagacag
    13861 tttattctga attcctttac attcgggata ggtggttcga tggccgcata ttgcggatca
    13921 gcccctttaa aatttctgaa agtcaagact ctcgggtaag taacccactc ggtttcaccc
    13981 tctttccgaa ccttaatctc agcacttctc aggttataac ccgatccgta ggcactctgt
    14041 ttagtgaccg aaaatccggt taaggtaaca ggccggtcca gtaccgtatt ccaccaacac
    14101 tctccggcat tagccactcc tcatgtaaac caagtagtat ttatctcacc gtcaatagcc
    14161 agatgtgcac catatttagc atcatcatcg gcataaacat tgctgcaact tacactccac
    14221 gcacttcgat ctacagcgga ccaattcccg ggtttcgtat aactggtata aagcacgctg
    14281 gtataaatcc ggatataaac cgtcttcata gatgtactga cagcctgttc gtccatgccc
    14341 gtaactcctt taagcgtcac gggaagcaca tatccgtcag gattagtcaa cttttctata
    14401 ttcttcaaaa cgacctgaaa agatgaatcg gccactgtct gtcccgtttt taagacaact
    14461 tcacttgttt caatggtata attatcttgg ggcaacaact tacatttcgt cttattggca
    14521 gaattgtaag tatccacttt cagcgtatct actcccaaag cggcagtgac atcccgcgta
    14581 accggctgta cggcacacaa ttgtatttca aaatcagaac ggtcggcaat agaggaattg
    14641 ctcacacaat ccaccactac cgcagcaccc atttcggccc ccggtgcaac tcccgttctg
    14701 atatatatct tttgatattt gtccatttca tcatcatcgt tgctgcacga agccaacgat
    14761 acaaaacctg ttatcaggca gattaaggtc acaaaattca aatgtctatt catatcttat
    14821 cttcttttta catagttatt gcttatcaaa acgaacatgc tctttccaga caagagttcc
    14881 tcctgccacc aaatcgtatc cgtgtccggt acagtcgaca aaggcatttc ccttaccttc
    14941 atccattttc caatagccta tcaggttcgg atcggcgggc ttcacggcaa aatacatgtt
    15001 ggactgaatt tgcgtctggc tgattgcgct cttccaaaga cgcacctggg ccatctgaca
    15061 attgttgcgg aagtagctac cgctcgaaac catgttcatc ttgtcgaatc ttaccggacc
    15121 accctttgtc tgcagagtca cgtcgagcac tccgttgata taaatcgaca ataacccgga
    15181 agaattataa acgaaggcca gatgatacca cttattcttc tcaaacaaag tcaccgtatt
    15241 gacctgactt ccaagtgtct tcacctgtaa tgaattataa gggatcatag cgtcaccgaa
    15301 acggatataa acctcgtggt cgctgctgcc cgaattaaat atagcctgat tattaatatc
    15361 gaatccgtcc atctgtaccc aagcctcgag tgaccattca ttggttgtca ctccccacaa
    15421 ttcgtccttg gcgggcttca cggcattggt cgtattcata aacggtacag actgtatcag
    15481 cggcttatcc agcaaaatga taaacttcga cgaaagcccg attgtggaca ccggtccctg
    15541 aatttctgtg agagataccg gaatagcata caattctccg ttttcgtttg aataaggttt
    15601 cactctaaac tcactgggga ttgcgctaac atcgcctgcc gctatcttta tctctttgtc
    15661 ataagtaaaa tactgctcgg gaaggacttc gtacgaagtt tcattagctt cattgtactc
    15721 tttaagaata gaaggatcta ccgtcaggac agcagtcaca ttttcggtta caggctgtcc
    15781 cacacgtacg gtcagagtag ttgttgttac attttcagga tcaacggtaa cctttgccga
    15841 accattctcg gatgcttcat tcaaataaat cgcattgtcg ataacctggt aatcggcatc
    15901 gttgcatcct gccaggatca tcggcagaac gaaacaggca agcaaatatt gttttattgt
    15961 tattcttttc ataatcaaat tctttaaagt cattttacag caggattcat tattctgatt
    16021 gcttcacgca ggtacttata ttcgatgtcg cccggatagt catattccat gtgataggtg
    16081 cctactccac ccttccgtac ctgttttccg tcaatagtcg gagtccagcg tgccatgccg
    16141 gcaagtgctc tcattttgtt tccgtaacga tctacataat cacctcctcc tgtcggagca
    16201 taagattcga aattctccgt aacgatgtac atattagcca ctttctccgg aggaagtatt
    16261 cctttaaagt tggcaatcgt accagccaga cgtctgtcaa gattagcatc ggaattaccc
    16321 gcaaggttag agtatgcctg cacaatgaaa tagtcaaagt aaggcccggt ttccggatga
    16381 atactttgag gctcgccatc aatcacaagt aaccgtcccg tacccgattt aggtccgatt
    16441 ctttc
//
