LOCUS       gnlProkkaMOLAGFBE_9    12374 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MOLAGFBE_9.
ACCESSION   gnlProkkaMOLAGFBE_9
VERSION     gnlProkkaMOLAGFBE_9
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 07:26:17
            Original ID  :: gnl|Prokka|MOLAGFBE_9
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 151508
            Orig. end    :: 163882
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12374
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:9314]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9314
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..12374
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12374
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(384..767)
                     /locus_tag="ctg3_162"
                     /transl_table=11
                     /translation="MKKIENNFAVTGFVAKDAEVRQFTTTSVARFPLAVARQEKNGEDT
                     KRISAFMNIEAWRKNENTGSFDQLTKGTLLTVEGYFKPEEWTDKDGVLHNRIVTVAVKF
                     YPAVDKEEEVPAEPAKKPKKGKK"
     CDS             complement(1525..1740)
                     /locus_tag="ctg3_163"
                     /transl_table=11
                     /translation="MAWLAVNKDGTEWIMPEKPVRGRCGHWEYLEEVYNVPIEIELPKG
                     TVYKLLGKELTWDDEPVELQTKTEKR"
     CDS             complement(1777..2064)
                     /locus_tag="ctg3_164"
                     /transl_table=11
                     /translation="MTNDVTNSNGRVTVDEVIHRDSVFRYQLLDRLRSDCEYYLNYGNR
                     HPKTLWAGDEKLQIEFMIKLHDSFKEGEKPEWLTMDKILEYSKRMIAQEE"
     CDS             complement(2537..2794)
                     /locus_tag="ctg3_165"
                     /transl_table=11
                     /translation="MNVTIEHVFCRYSDEAEEIYFRIMNTILFATDETELRASMERLKN
                     ETTLDDYFIFGYGAHHIWIKQRRPSDKNRIFKHRIMVAHF"
     CDS             complement(2799..3095)
                     /locus_tag="ctg3_166"
                     /transl_table=11
                     /translation="MGEYKFYQDRKVTSWERDYFSVKADSYEEAEAIVRSWNCEDVSNI
                     IDNRLCYEEWQALTDTSESMLPEENDGNPTIEIFNQDGESIMTNVPETPQSNQ"
     CDS             complement(3108..3440)
                     /locus_tag="ctg3_167"
                     /transl_table=11
                     /translation="MTQIATKFVKWDIPELATLQDSKVYKLRVHLNNGGKLNREEKNWI
                     TRNVWESIYFKRGIALSGYHFDFSDILKRYFVKQHGSIHEYYAIDKTALRSILYGRIED
                     IVEVSG"
     CDS             complement(3455..3631)
                     /locus_tag="ctg3_168"
                     /transl_table=11
                     /translation="MYEYEEDSDIIGLSCTLLNPYKGYMEGTIVGDYGNTIVVRLESGK
                     EISEYRDEVIIHD"
     CDS             complement(3650..3946)
                     /locus_tag="ctg3_169"
                     /transl_table=11
                     /translation="MANYATNIFHASTENKQDLNKIEAFLDDNFNGFVNRYGDTVDAEF
                     DSRWEYPEKAINELIALLAAKDKIYIRILTYELEDEYVSFRIFSQGKWNIKLS"
     CDS             complement(5001..6122)
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 1.6e-33.
                     Score: 107.9. Matches aSDomain:
                     nrpspksdomains_ctg3_170_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 75.5; E-value:
                     6.4e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_170"
                     /sec_met_domain="Aminotran_5 (E-value: 1.7e-29, bitscore:
                     96.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLLVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKVSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        complement(5025..6032)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg3_170_Aminotran_5.1"
                     /evalue="1.60E-33"
                     /label="ctg3_170_Aminotran_5.1"
                     /locus_tag="ctg3_170"
                     /protein_end="366"
                     /protein_start="30"
                     /score="107.9"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLLVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKVSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             complement(6132..7256)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 61.4;
                     E-value: 1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_171"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-19, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-20, bitscore:
                     65.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIARGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             complement(7273..8574)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_172"
                     /sec_met_domain="CTP_transf_like (E-value: 2.7e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.4e-62, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(8595..9314)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_173"
                     /sec_met_domain="NTP_transf_3 (E-value: 5e-16, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(9378..10526)
                     /locus_tag="ctg3_174"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(10537..12372)
                     /locus_tag="ctg3_175"
                     /transl_table=11
                     /translation="MLKNALNKIYNGLNNTTDPTSDIRLTLGNIRTIQINVMGEVVQPG
                     TYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVYEFIMKGNTQDDIRLQ
                     EGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGFEADAYTRSLRVVRQN
                     GEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAVYRPGIYQLSGKLNTI
                     RELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGTSPNLALMKNDILYIP
                     SIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEAASTVRIDISRRIKNP
                     RSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPGYQAQQNVAIEGEILF
                     GGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKKRMGDVIRLMSRQLGE
                     AMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPKNTNTVTINGAVMVP
                     NTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVP
                     GKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
ORIGIN
        1 catacgtctt gaattttaag tttgactttt gtttttttat ccctgccttc ggagggtttc
       61 cctcgtccgg cgggatttga ttttacgtgc ggaccacaag gcggacagaa gggaaacaag
      121 gcaaggagga agcggatagt cctatggacg atttcatttg tgttgaacaa gtattgacga
      181 gcttgcgagt tgatggttgt taacctcaaa tgaagccgcg ccttgccggt tcccgaccgc
      241 cttaactttg cacgggaaaa tcaatggacg acggcggact cttcgtgtgg agtatgaagg
      301 agtataaaag tatagacgtt ccggaacggt aacgagcaaa acaaaagcgg ccttcgggcc
      361 gctttgtctc aaaaaggcag gaattacttc ttgcccttct tcggtttctt tgccggttcc
      421 gcaggaactt cctcctcttt atcgacagcc ggataaaatt tgactgcaac cgtcacgatg
      481 cggttgtgca gcacgccgtc tttgtcggtc cattcttcgg gtttaaaata gccctccacg
      541 gtaagcagcg tgcccttggt gagctggtcg aacgacccgg tattctcgtt cttgcgccac
      601 gcttcaatgt tcatgaaagc ggatatacgc ttggtatctt cgccgttctt ctcctgacgg
      661 gccactgcca gcgggaaacg tgcgacactt gtggtggtga actgacggac ttcggcatct
      721 tttgccacga atccggttac tgcgaaattg ttctcgatct ttttcattgc gattgctttt
      781 tgaagttaat aaatcagttt tacggtgcat aaaagtaggt gcagtaaagg gctgcaccaa
      841 ggatagcgca taaatactct ttattttgga ggcgaagccc caaaccgcaa gcccgataaa
      901 ggaagatttg tgcgatacgc cattggtcaa gaccatcggg tcgcgcccgt ctgcatacta
      961 actttgcaac gaaaaacgat atggcgactt caaatagaaa gcggtcgcga aaaagtcgag
     1021 gcgaaacaat ccgcagcgga ctcggaaaca tgaaagacct gtccgtccac cgacacaaga
     1081 ccgctcccgt tccggcaggt gggcgggaag aacatcaggc gagaaagtgt atcggctgtt
     1141 tggggttgaa gcggcaagaa cgatataccg tttaacaacc atatacgctg catcgtggaa
     1201 aatactatcg gacgaagatc cggcaaaagg cgtgtgcgac gtatcgatat cgctgtctct
     1261 atccggcaag agaaatgagg gaaagaagag gtaaaggaaa aatggccgaa gtctgccttg
     1321 aaacaaagcg gagaagccgc ctttgcatga gtggccgttc gatataaaag gatatggcgc
     1381 agccgaaatg tataaagggg tatttccgaa ggaaacggta tgagtgtctg ttcggaaata
     1441 aaagagggta tcgcacccgc gtatctgttt tagattttag ccggtgtaac cgggctgaaa
     1501 ctggtactcc agcccgtact acatttacct tttttctgtt ttggtctgta attctaccgg
     1561 ctcgtcatcc catgtcagtt ctttgccgag aagtttgtaa acagtccctt tggggagttc
     1621 tatctcgatt ggtacattgt acacttcttc caaatactcc caatgcccac accggccccg
     1681 aacgggcttt tcgggcataa tccattctgt tccgtcttta tttactgcca accatgccat
     1741 aatatcacat ttttagtctg ttccttagta gtaattttat tcttcttgag ctatcattct
     1801 cttactgtat tccaaaattt tatccatcgt aagccactcc ggtttttctc cctccttgaa
     1861 gctatcatgc agttttatca taaactcaat ttgcaatttt tcgtcgccag cccataaggt
     1921 tttggggtgt ctgttaccgt aattgaggta atactcgcag tctgaccgta agcggtctaa
     1981 cagttggtat ctgaaaaccg aatccctgtg tattacttcg tctaccgtta ctcttccatt
     2041 tgaatttgtt acatcgtttg tcataaccta taaaattttg agttttcttt ttccctcttg
     2101 tagcacctgc tactttcggg cctgatttaa ttatgtcgcc tcgaaaggtg tcatagctct
     2161 ttatgcaagg tttcacgatt aaatactacc cgtgcgaagc ggagggtgga gattttgtcg
     2221 tgaaccgtca ggctttgacc ttgcatacaa gaacggcatg acaagtacct ttgcgacaca
     2281 atttatatca ggcagcccga aagcgatgtg cgaacacagg gaagagaagg tctcgtgtaa
     2341 aaggttgatg ggcgataaaa agggtttgca gcgaaaagag aaatataaac gggtattccg
     2401 gggcagtata aaaattgatc gtgaggataa aagggggatt gtgccagcat gtctattgcg
     2461 agaaagagga acgggctgaa gctggtagtt ccggttcagc ccgcaaagcg cattggaggt
     2521 cttttgcctg ttcctgtcag aaatgggcta ccataatccg atgtttgaaa atcctgtttt
     2581 tatcgctcgg tcgccgttgc tttatccaga tatggtgtgc tccgtatccg aatatgaaat
     2641 agtcgtcgag cgtggtttcg ttcttcaagc gttccatact tgcccgaagt tcggtttcgt
     2701 cagttgcaaa aagaatcgtg ttcatgattc ggaaatagat ttcttccgct tcatcgctat
     2761 agcggcaaaa gacgtgttcg attgttacgt tcatggttct attggtttga ttgaggtgtt
     2821 tcgggtacat tagtcattat tgattctccg tcttgattga aaatttctat tgtcgggttg
     2881 ccgtcgtttt cttcggggag catagattcc gatgtatcgg tcaatgcttg ccactcttca
     2941 tagcaaagac ggttgtcaat gatgttcgac acgtcctcac agttccatga gcggacgatt
     3001 gcctcggctt cttcataact gtccgctttc acactgaaat aatcccgttc ccaacttgta
     3061 accttacggt cttgataaaa tttgtattct cccatatcct tgttgtttta accgcttact
     3121 tctacaatat cctctattct gccgtacagt atcgagcgta acgctgtttt gtcaatcgca
     3181 taatactcgt gaatacttcc gtgctgtttg acgaaatacc gtttgaggat gtcggaaaag
     3241 tcaaagtgat aaccgctcaa ggcaattcca cgtttgaaat agatactttc ccatacgtta
     3301 cgggtaatcc agttcttttc ttcccggttt aacttgcctc cgttgttcag gtgtacccgc
     3361 aatttgtaaa ccttgctgtc ctgcaatgtc gccagttcgg gaatgtccca tttgacgaat
     3421 tttgttgcta tctgtgtcat acgtttgcta tcgtttaatc atggataatc acttcatcac
     3481 ggtattctga aatttccttg ccgctttcaa ggcggacaac tatggtattg ccatagtcgc
     3541 ccacgattgt gccttccatg taacctttat atggattgag caacgtgcag gacaaaccga
     3601 taatatcgct atcttcttcg tattcgtaca tagtgaattg tgtttaggtt taggataact
     3661 taatgttcca tttaccttgc gagaatatcc gaaagctcac gtattcgtcc tctaactcgt
     3721 atgtcagtat gcggatatag attttgtctt tggctgccaa taaggctatt aattcgttga
     3781 ttgctttttc cgggtattcc cagcgggaat caaattcggc atctaccgtg tcgccatacc
     3841 ggttgacaaa gccgttgaaa ttatcgtcca gaaatgcctc tatcttattg aggtcttgtt
     3901 tgttttccgt acttgcgtgg aaaatgtttg ttgcgtagtt tgccataact ttgaatttta
     3961 agttttcttt tttccctctt gtagcatcca gctactttcg ggcttgattt aattatgtcg
     4021 cttcaaaagg tgtcatggct ctttatgcaa ggtttcacga ttaaatacta cccgtgcgga
     4081 acggagggtg gagattttgt cgtgaaccgt taggctttga ccttgcatac aagaaagaca
     4141 tgacaagtac ctttgcgaca caattcatat caggcagccc gaaagcggat gtgcgaacac
     4201 agggaagaga agatctcgtg taaaaggttg atggtttata aaaagggggt tgcagcgaaa
     4261 agaaaaatat gacgtggaat gtttttttct tttggctgta caatgggacc ggagtgtttt
     4321 acgaagttcg ggaaaaggtt tagtttagtc cattagccta tatatatgct aaatcaaagt
     4381 aaactatatt taggcagcca aatttgcctg cctataagtt tttccttatc tttgtatgaa
     4441 ctaaagaata cttgcttttt tcttttggct gcagtggttc ttggaagctc acatgcaacc
     4501 atcggacgaa aaaaatctgg tgggaagctg ttcaagaagt cccgattata agcaagtgca
     4561 aagaaagaaa cagagtgaaa acaaaaaatt gggaaatacc tttaattaac gattttgttt
     4621 cttgtttgtt ccttaattaa aatcgtgaaa ttttcaacaa tctgattttc aaatcattat
     4681 ataaactatt tttgagagat tgaatttatt tccaatattc tcactaattg gttattatct
     4741 tcttcgcccc ttaccgcaat tctaatatgg tctctcccac taaaagcaaa ttaccctaca
     4801 caaacattat ctcctataac taccgatgcc tttttataag aataaagaac tcctaatgca
     4861 tcacctcaaa ttaatattgc catatttgcc tactaagcga aagctacgaa taggcactcc
     4921 agaaataaca ctttccggat ggaagtgtat accacgaagg gaaaaataaa aatgacgaat
     4981 cttcaataat atttctgcaa tcatgacatc ggtaatgtga cgttataatg atttaatgca
     5041 gcttttagta ctttaaagaa gttctcaata tcatctactt ctatctctcc taaagcacag
     5101 attctaaaag tatcctcagt tgatatctta cctggataaa tcgtaaatcc acgctcataa
     5161 caataatcat gtattttctc aaaatcccag ttgggatctt ctgggtattg aactgagaca
     5221 accagtcctg actgccattc acgctttatt acacttttaa gaccaatttc atttatacct
     5281 gaatgaatag cctcaaaaac tcttttgtga cgggcaaact tagcttcttc gcccacttca
     5341 aaatattcat ttaatgcctg acgagtggcg taaatagttt gtaccggtgg agtaaaatgc
     5401 atttcacctg ttctctcaaa attctcatac tgcaaataaa gattacaata gtaagaacgc
     5461 ttgggatatt tttttgaaac cttaatctgt tcctcattgc ctataataaa agaaagacct
     5521 gtcatcgctt gaagtccttt ttgagcagat gccatacaaa aatctacatt atctttctct
     5581 atatcaaaag gaatcatgcc caaagaagaa gtagtatcga cgacaaattt agcctgatat
     5641 ttatgagcta tagcgcccat ctcgcgaata gggttcagaa ttcctgtacc cgtctcgtga
     5701 tgagtagtat aaaccatagc tatatcagga ttttcttgta acacattttc cactaccaat
     5761 aaatcaggac gttcataaac agaaaattcc aaattaatat gaggcaaacc ataatattga
     5821 cacacttcta cagcacgggt actatatgcc ccattattca ctataagcac ccttttgtct
     5881 tcaggaagaa gagaatttag acatatatca atattgatag ttcctgagcc acaaaataat
     5941 acagctgtat gtttttccaa attcccatga gcaactctga ccaaatcgtc ccgaagttgt
     6001 ttcatcatac ctgcgaattc tttctcgcga ggacaaatat ccggaacaac ttgtgccatt
     6061 tttacactgt cagtagtagt ggcaggccca ggatttaata atatttttct ttctattttc
     6121 atcgaatata tttattttaa aaaatccata aaatgctcct tattctctat aggagtagtc
     6181 gtgggacgtc ccaaattctc ccgagaatct atcttaacct ttatttccaa caaaacagga
     6241 ccacataact ttggaagctg cttcattgct tcttcaattt caacttttgt acaaacagta
     6301 taagtatgct tatatccgct cccccgggca atagccggaa tatctaaact aaatcctaaa
     6361 gtaggctgtc ctcctacaga ctcgtgagca ccattgttaa acaaaatatg ataatagttt
     6421 ttaggagata aatcgccaat gttactaatt gcccctaaat gcataataaa tgctccatca
     6481 ccatccaagc aataaacagg tctatcttgc tttgctatag caatacccaa agagattgat
     6541 gaactatgtc ccatagagcc taccgtgaga aaatcatgtt catgaccttg ctctttcatt
     6601 tctcgatatt caaataactc acgagaaagc ttgccagtag tagaaacgac cactgaattt
     6661 tcaggcagat aatccacaac tatttgcaaa gcatcctcac gagataaagg ataattacat
     6721 ccgaattctt tttgaagttt atatttgcca aaaacatctt tccgaataat tattgcatga
     6781 ggaatattct tagtttttgc tgattgtatg atatcatgga gctgaataaa tgcatcattc
     6841 tcatttgaat caagaattat ataaggaatc cgcattgctt tcaacaaatc taaagttacc
     6901 tcaccctgtt ttttatgctg aggttcatct tttgttcccg gttcaccacg ccagccaatc
     6961 atcaaaagca ttggaaaact gtatacttgt tcatctgcaa gagacagcag aggattaaca
     7021 gtattaccca agccggaatt ttgcatataa accacaggaa ccttacctga tgccatataa
     7081 taacctgaag caattcctac agccgcacct tcattagcag ctatgatatg tttctcacgt
     7141 gaagtatggt ctgtgatata ggcacaaata ttttttagta atgagtctgg aactcctgta
     7201 aaaaaatcaa cgtcatgact cagaaacgtt tcataaactt tttctacgct taacataatg
     7261 atattcctct ttttatttag tacccggaat cagttccaat atttccttta tgggcataca
     7321 cagttcgcgc acctctaaag cacgttcatt ctctaatatt gtctttgcga cattcatcat
     7381 agcaggataa gcggcacgaa gcatatgatt agcataaata attatattca caccccaatc
     7441 acacaattca gactcataaa tatgatcata tgtagtaggc acaaccacga taggtacatg
     7501 agcatactgt tttcgaaacg ccaaacaaaa ttcttttata tcttcacccg acttattttt
     7561 gctatgtatc ataataccgt ccgctcccgc ttggacatat gcaaaagctc tctctaaagc
     7621 atcacttacc ggctttcccg ctataaggct ctcaatacga gcgataatca taaaatcatc
     7681 agtaatctga gatgcctttc ctgctttgat cttattacag aaaccttcga ttgtatcttg
     7741 agtttgaata acatccgtac caaacaatga attctttttt aatccaactt tatcttcaat
     7801 tattatagct gagattccat gacgttctaa agtgcgtact gtaaatacga aatgttcaat
     7861 tttaccacct gtatctccat caaaaataat aggtttagta gtacactcca gaatattatt
     7921 caaatcttgc aatcgggtag ttaaatcaac cgcctcaata tcaggtttac ctttactggt
     7981 tgaatccgta aggctactag accacattcc gtcaaatact tccctcttat ccccttttaa
     8041 tatttcctga ttttcaatta tcaagccaca tagtccatca tgagcttcca aaatacgaac
     8101 tacgggtttg gcatttatca aacgacgaag tgattttaaa cgtacatcgg gggttgtacc
     8161 tatagcctta atatctttat ccaaagaaga tgaattaatt cccaaagtat atggaatttc
     8221 gataaccttt cctccctgtt cattcatcac ttcaaatacg cgcacacgtt cttcacgtaa
     8281 aggcccggtt ttccagtcgt caccatgaat tatatagtca ggtttaatgc gtttgagatt
     8341 ctcaacatag ctccattctt cttgaggaac aactttacat acgcctttaa tattctgaac
     8401 tacctctttt cgttgttcat aggtcagata aggaaggcgt ttatgctccg caatagcttt
     8461 atctgtaaga agaccaatta taacatcacc gtatttagta gcctcattaa taatgcggat
     8521 aagtcctgga tgcataatat ccgcagtcat cccaatataa actgtcttac tcataatttg
     8581 atatattatt ttaattaaca atacggaaca atatatttct ctgcatattc caaatctgat
     8641 atgtcatcga tttcatacca tttcagccct tctactttat gcacataaac aggagattga
     8701 gaacaagata ttcgtagtaa ttcatactca tatcccaaat tgggttgttc atcaacaata
     8761 ctcgcataat cagcacacat tattttgtaa aaggaaccgg atagtttatg gatgccgacc
     8821 aattcgcctt tagcgtttag tttattctta ttgacagaac atgaagaaag gcgaaaatta
     8881 tcatcatgtt ccacataata ctgatcttga aactttgtca ctggagctat tagcattgca
     8941 tctgccgcag gacactccaa taagctcatt attgcttgtt tctcaaaaat caaatctgac
     9001 tctaacaata aaaaatcatc attgcccaga atctcccgcg tattatataa agtatacata
     9061 ctatttgttt cagcataacg aggactaaaa caggtttcaa gcataggata gtctgtcttc
     9121 aattcttcat aaacttcttg tttatatcct gtaccgatta caattcgctc aatgccacat
     9181 gataacaaag tatcaataga acgaactatc attggaatac ctcccacttt gacgaaccct
     9241 ttaggtatca attctgtata ttggccaaaa cgggttccca tgcccgcagc cattatcata
     9301 gctgtacgta tcattcgttt aataatatag taagtgaatt taattgatat aagaatgttg
     9361 taaacgacgt tttagcatca tttatcctgt tctatctcct tatttttcag ttcttttctc
     9421 aagctagcca gcagactttt gccaaaaagc acccacacga gagtaccaga tacggacagg
     9481 aacacaaata ataaaatata aattttgagt cccatacctg aaggtttcaa aggtacaacg
     9541 gcaggctcaa ctactgcaaa gactggcttt tcctcctgta ctttggctct ggatacctgc
     9601 aactgattag caacctgact atatatctga taagccaaac tcatgtcgtt ctgtaaacgc
     9661 tcctgctcag cacgtacact ttgaagaacc acattatcat gggcgtctac ataatccgca
     9721 tattttcttt gagcagcata atattcctgc tgacgttctt taaacaaccg ttccaaatac
     9781 gcacagtctt cttttacttt tgaagttcga tacccaataa tatattcctg taatttatga
     9841 acgacagaat ctgctataac cgcagtgatc tgcggatttt gtaaggtgac cgtaatgctc
     9901 gttatggcgg ttttcttatc aatggatgca ctaatcttct ttttaagaaa attaatcttc
     9961 tcatttactt ctttcgtcaa ttcgatagtt ccttgccgcc ctccactggc aggaaccgta
    10021 tcttctccga ataatgattt aactcctcct attactatgc ccggaaaacc tataagataa
    10081 tcccaccaag gagatgactc ttcatcgaga taagacccca aagtcatttt atcatccttt
    10141 ttagaaacgg agacttccat ttctaaaagt tccaataaaa aaggagttga agaaacaata
    10201 tctgctgaaa gagaagcgtt caaggcatct gtgctttccc ctattagagc cccatctccc
    10261 aaaaacgagg cagcaagtcc ggctaaacca ttacttccct tcgcattacc catttcagga
    10321 gaaagggtaa cctttactgt atattgcttg ggaatgctca atgccaccac tatagcaatt
    10381 attactccca ctccagcagc tttgcatagt actccacgaa cagtaataat cttataaaaa
    10441 atagccatca agtctatttc catttcatca tctttccttt tatccacttc agaaaacggt
    10501 tcttgataag attgcttttc aatcataata ggtcatttat ttctttatca aattagcaat
    10561 agaagcaatc atcattccca aagaactgaa ggaagtagca taacctaaaa tattagctat
    10621 gttccctttc ttcttagcct taccaggcac aataatctca caccccggct caatctgttt
    10681 cttaccacta cccttaacct tcgtcacctg accattcatg taaacaatga acttcttact
    10741 cttccttgca ttatcagaac agccaccggc ctgattcagg taataatcca cattctttcc
    10801 cttcatataa gaaaccgtat tcggaaccat gacagcacca ttgatagtta cagtattagt
    10861 attcttaggt atggagatca catcaccttc acgtaagaca agatcggcat tacttttagg
    10921 attgctcaag gctttttcca aatctattcc aaccgtaaaa gtatcttcaa cacgaatacc
    10981 caaagagtca atcatggctt cgcccaattg cctgctcata aggcgaatta catcacccat
    11041 acgtttcttt tcactagcgt tagccacacg ggtcagtttc gcaccacgca gataggcata
    11101 attggtcgga ccgccggctt tattcactaa atcggaaaga cgttcctcac ggctggtcat
    11161 ggcgtaattt cctccgaaaa ggatttcacc ttcaatggct acattctgtt gtgcctgata
    11221 gcccggactg cgacggacat aaacctgatc ataaggctca aggataaaac cgggctgacc
    11281 atctattaca aaaccatcct ttaaagagaa ggtatacatc tgaccaatcg tatcattatc
    11341 cgcagtacta cgaggattct tgattcgtct cgatatatca atacggacag tagaggcggc
    11401 ttctttcaag ccaccggcct gaatgatcag atcctcaagt gtcatgttat ccgcataagg
    11461 ataggaatca gggtgggcaa cctcaccgtg aactgtgaca ttaccccggt cttccaggtc
    11521 atggatactt ggaatgtaga ggatgtcatt cttcattagg gcaaggtttg gggaagtgcc
    11581 gtccatgata gacttaatgt ctatctgaac aacttcactg gtcaggtctt cacgctggcg
    11641 atagaggacg gcacgattca ggaaagcgtc accggtcaga ccctgagctt catggacaag
    11701 ttcgcggatc gtgttcagtt taccgctgag ctggtagata ccgggacgat agacagcgcc
    11761 acggatttcc agtttgtttg tgaagcggtt aaggatggct tcggcggtta ctacgtcacc
    11821 gttacgcatt ttataaatgt tgtaatctat atctttgact gtgttgactt cgtattcctc
    11881 accattctga cggacaacac gtaatgaacg ggtgtaggca tcagcttcaa agccgccggc
    11941 atatttaatg agagtagcaa ggttctcgtc tttcttcatt tcaaaacgca taggacgttt
    12001 taccttgccg ctaatcttta ccaatacatc ataggcagga acaatcacaa cgtcaccttc
    12061 ctgtaggcgg atgtcatcct gtgtgttgcc tttcataatg aattcgtaga cgtcgatggt
    12121 ggcaatattc tttccgttgc gtaccaactg aacgtttcgg aggctaccga tatcactcac
    12181 accgcctgca cgataaagcg catggaagac ggtagagaag gaagaaaggg cgtaggtacc
    12241 gggctgtacg acttctccca tcacattaat ctgaatagta cggatattac ctaacgtcag
    12301 acggatgtcg gaagtaggat cggtagtatt attcagaccg ttatatattt tattcagggc
    12361 gttcttcaga tagt
//
