LOCUS       c00072_gnlPro..        17545 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MIKPNMIO_93.
ACCESSION   c00072_gnlPro..
VERSION     c00072_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:30:16
            Original ID  :: gnl|Prokka|MIKPNMIO_93
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17545
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17545
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4574:7545]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4575..7545
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17545
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17545
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             103..435
                     /locus_tag="ctg72_1"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             416..721
                     /locus_tag="ctg72_2"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(791..2905)
                     /locus_tag="ctg72_3"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIVGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYACTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(2992..3222)
                     /locus_tag="ctg72_4"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             3416..3919
                     /locus_tag="ctg72_5"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             3979..4146
                     /locus_tag="ctg72_6"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             4133..4582
                     /locus_tag="ctg72_7"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(4575..5303)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 71.7;
                     E-value: 2.5e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_8"
                     /sec_met_domain="Radical_SAM (E-value: 1.5e-28, bitscore:
                     92.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKTLVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(5317..7545)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg72_9"
                     /sec_met_domain="Gly_radical (E-value: 4.2e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             complement(8016..10634)
                     /locus_tag="ctg72_10"
                     /transl_table=11
                     /translation="MQLVLLIVVVSLVAISVIAVATIRIRLKNKSKELSEKLNHISSYS
                     NKSNYEQAKERLSALNNEAFIDIPTDLNNVFSCKIISATQEKDFTNHYIPYFQEAHSLV
                     KRLEAFNITPSVAISNLIRDFGNINKIVKQHNDAVINSLLDTHKEFFDHCLKYPLDKQQ
                     RRSIVSEEDNCLVVSSAGSGKTSSIVGKVKYLTEIKGIVPHRILLISYTNKAAAELTER
                     MATNGLKGYTFHKLAIDIIGRATGTKPSICDNTDSLFVDIYHTLLGNKDFKNSIVEYFI
                     DYQSNEADWEQRKNERREKLSEQKNVQLKAMCPDMDGRAIYVRSEQEQKICFVLSSLGV
                     RFRYEEAYEHQLADEMHSQYRPDFSIYFEQNGVTKRIYLEHFGVDEHGLVPAWFAKDKN
                     ITYEEANQKYNDGITWKKAAHEKFGTQLLVTSSADFHYSDIRDKLRKLLDDAGVPIQEK
                     TDEELYDLVLPKGSKQEKAFIRLVVTFVTLVKSSCKSVKDVLKRAKYAEDERSVFIIKN
                     IFQPVYERYISALRDNNQIDFTDAILQATEICRVSRPVEYDYIIVDEFQDISVDRYNFL
                     KVLREGNPPAKLYCVGDDWQSIYRFSGSDMALFNQFSEYFGATEINKIETTYRFGEPLV
                     SLSSHFIQRNKSQIQKDIHSFSSEMKTELEFYSYDRRDYCNTIGQLVASIPSDKSIFLL
                     GRYSFDDYYLSFMYQSIKEGNRFFYVIGGRKIEFLTVHKSKGLEADYVILLQCNKDTYG
                     FPSLVSDDPVLNYVLTKSDQFPYGEERRLFYVAITRAKMKTLVLYDKRFPSVFVDEFLH
                     PEKVSEESYVKHPNANKRWTRSADQFLLKLHNEGKSVKYIANKMGRSQTSIVMRLNKLN
                     Q"
     CDS             complement(10650..11309)
                     /locus_tag="ctg72_11"
                     /transl_table=11
                     /translation="MKKLIVSFALMVITLASYAQVYKMYSTRNYHNQLRLNTMTGEVQQ
                     IQDDGQSWIICSTREISGDKESRFCLYETQNMWTFIMLDTYTGKNWQVQFSVKGEDYMF
                     AAPINIFSLAYPEATSNWTNRFQMFATQNMWTFILLDSYNGRLWQVQYSTQDLDNLFCI
                     PINKDELGSDNEKCIFSIQPLTSMYQYYLINDRTGDMWKFQWSTKGDDYRWIEKFK"
     CDS             complement(11341..11838)
                     /locus_tag="ctg72_12"
                     /transl_table=11
                     /translation="MNAIKNWLLVFCTILLANGCAPLRTPVIVRNAPIEMYKYAYISPT
                     KELTSSTGGTYGGQYGIYGSSTTKSVNPSDVIAGILIKQGYIILPELKSELANETLIVN
                     YGESGRRNRGLGYTIEVTIQFSSAKTNEMICSCTAEGQGETEADDIRQAIRRALSSLFP
                     EK"
     CDS             complement(12141..13544)
                     /locus_tag="ctg72_13"
                     /transl_table=11
                     /translation="MATKSSIHIKPCNIASSEAHNRRAAEYMRNIGESRIYVVPELSTD
                     NEQWINPDFGTPELRTHYDNVKRMVKEKTGRAMQEKERERKGKNGKTIKVAGCSPIREG
                     VLLVRPDTTLADVRKFGEECQRRWGITPLQIFLHKDEGHWLSGHPEAEDRESFQIGERW
                     FKPNYHAHIVFDWMNHETGKSRKLNDEDMTEMQSLASDILIMERGQSKAVTGKEHLERN
                     DFIIEKQKAELQRIEETKRHKEQQISFAEQELKQVKSEIRTDKLKSVATDAATAIASGV
                     GSLFGSGKLKDLEQSNENLRHEIAKRDKGIDELKAKMQQMQEQHGKQIRNLQGIHNQEL
                     ETKDKEISRLNTILEKAFNWFPLLKEMLRMEKLCYAIGFTKDMVNSLLTKKESIRCNGK
                     IYSEEHRRRFEIKNDVFKVEKSPVDDNKLVLTINRQPIGEWFKEQWKKLRQGLRQSAEE
                     PRKSRGFRM"
     CDS             complement(13761..14717)
                     /locus_tag="ctg72_14"
                     /transl_table=11
                     /translation="MDIQTAKQIRIADFLHSLGYSPVKQQGINLWYKSPLREEAEASFK
                     INTERNQWYDFGLGKGGGIIELAAHLYATDHVPYILKRIAEQTPHVRPVSFSFGKQNSS
                     EPSFQQLEIVPLSSPALLAYLQGRGINMELAKRECSEARFTHNGKRYFAIAFPNGSGGF
                     EVRNRYFKGCIAPKEISHIRQSGKARNTCYVFEGFMDYLSFLTLRQESCPNYPELDGQD
                     YIVLNSVSNVNKALYPLGSYERIHCFFDNDHAGMEALRQIRKEYGRDLYIRDASQTYNG
                     CKDLNEYLQKQVERKRQVRSVKETRSQSPKKKNGFQL"
     CDS             complement(14942..16018)
                     /locus_tag="ctg72_15"
                     /transl_table=11
                     /translation="MDYMKDNKEISAEEAVILWQASRLSLSKSYEKAPEILKVHGSVIG
                     TLGNFSASIGKAKSKKTFNVSAIVAAALKNGTVLRYVAELPEDKRKILYVDTEQSPYHC
                     LKVMKRILRMAGLPDDRDNENLEFLALRKYTPEQRIRIAEQAIYNTPNIALVIIDGIRD
                     MVYDINSPGESTRIISKLMQWTDDRQIHIHTILHQNKGDENARGHIGTELNNKAETVLL
                     VEKDKNNGDISKVSAMHIRAMDFEPFAFRINDNALPELMEGYKPEAKKPGRPEEEKFDP
                     YRHITEQQHRIALEAVFGLKEEYGYKELENALIKSYTSIGVKLNHQKAVPLITMLRNKR
                     MIVQENGRKYTFMPDFHY"
     CDS             complement(16033..16341)
                     /locus_tag="ctg72_16"
                     /transl_table=11
                     /translation="MTNLQELLLKPVWQMTGEEFIFLSKHASNQTEAQPQPITDMERKY
                     VYGIPGIAKLFGCSLPTANRIKKSGKIDKAITQIGRKIIVDAELALELAGKKTGGRK"
ORIGIN
        1 tcctctctca ctcctctcac ttttgggggt gaagatgatg aaaaataata taaaacgagg
       61 aaatgtgttg tatagttgaa caacattcct tatatttgcg ttatgaaaag agaaataata
      121 gcatataaag gatacttcaa agaattcttt gaaaatttag atgctggcac ccaagataag
      181 atattgtatg tgctaatgtt attgcagaca caagacagaa tacctttgaa atttatgcgg
      241 ttgatagaag aaggacttta tgaacttcgt atcgagtacc aaagcaatat atatagaata
      301 ttcttttgtt tcgacgaagg gcgtattgtg attctgttta acggttttca aaagaaaacc
      361 gaaaaaacac caaagaaaga aattgataaa gcaaagatat taagaaagga gtattatgga
      421 agcaaaaaca aatgaggaat tctttaatgt cagtgcatta atagatgagc gttttggtaa
      481 ggaaggaaca gcttctcgtg cagaggcaga agaaaaggcc tacgcctttt atacaggaca
      541 gattatcgag gacgcaagaa aaaaggctaa aatcactcag gctgaattag cccggcgtat
      601 cggctctgac cgttcttata tttcaagagt agaaagtggt cagacagagc ctaaagtatc
      661 tactttctat cgtataatga atgcgttagg ctgtaaaatc gaattttcaa tgattttgta
      721 aaaacaataa atgcagagta tctgtcaaga tgactctgca ttttgctata ttcacaaggc
      781 tttcccgctt ctattcatac agcctgtttg attttacctg ctcgatatct ataataaata
      841 cggcatatcg gcgcccgtta tttccttttt tagattcaaa atggtgctta gtcatcacct
      901 tccccaactg tatttttgat ccgatggaat actgataacc ggtacgctca cgtattagtt
      961 ccgcaatctc actgacagtc agataataaa ccttctcgaa acgttccggc ttgcggatat
     1021 gcgtaagaac catttcttct tccggtgaat gaaagatgaa agcctcgtta ttctcttcaa
     1081 gccgttcatt gtccgcttgc gtgaaccagt attgatatcc cggcttattc agcagatatt
     1141 tgatctgagc atagagctgc gcataattga tggtaataaa ttggatggaa taaggatgaa
     1201 aacaaaggaa acgccggttg cctgtcgtgt cgtgaagcac ttcctgataa ttgcaggttc
     1261 ctgcaaaaga ggccgtatga gggaagtttt gcgaacggcg tgcataaggc agacggaaac
     1321 tgatcacttt gcgcgttacc aaatctttga atgcattcag ttcccgaccg ctcatccctt
     1381 caaactcgtc gagattgatc agcatggcct gcgttatttt ggctaaatca tctttattgt
     1441 tcgaattgat tagtccggta gagagataag cacgcagttc gggaggcagg agattattga
     1501 taaaggtagt ctttcctatg ttctgtatct cgctgcatag cagaagtacc gtgtgattga
     1561 caatattctc ttgagtagcc gctgcgcaca tcgccaccag ataacgttcc aggcattccg
     1621 cccaaaactc ctgatgactc gtctggacac tatccgccag gatacggata tagtcggttc
     1681 cgtcccattc gggcagtaat tcaaaatact cgcgaatggg atgatacgac tggctgaaat
     1741 cggagtaaat cagattttcg attgttttga cagtgcaggc atatcccagt tcgttgattt
     1801 ctatccagat actgttttcc atcatctcat ccaagatgcg gaaaggctcc ggtttctcgg
     1861 tgtcgggatg ccttctgcga tattccatga tatgcagcac ttcgttgtag cgtgtttcgt
     1921 agtgctcgct gatatattgc tctatccgta atattcgttt ctgcgtgcca tttagcttac
     1981 aggtattaaa ttcgtcggta tgagcgtagg cgctattgat caaagaggct gtctcgtccg
     2041 ccggaaagtc tgtaaactgg cttttgataa aggcggatgc ttcctcctgc ggaatgccgt
     2101 agcgattgaa ggtacatgag agatggtgca gataattgtt ccggttgccc actatgtatt
     2161 tttcggactt gttgtgatag taggttaaag tcagcaccag agaagcgttg gcggaatggg
     2221 cgttgagcgc tgtgtcttca ttcgtcgggg ggccgtccgg aggagtctgt tgtttactgc
     2281 cggagagatt tttacgattt gaaaccttgt aggatgcctg aggttgatct acaagaaaag
     2341 cgtcagcgtt cggattgaaa taaatctccg gatcgtaaga gaacagacaa gtgcgtgcca
     2401 catcctgacc ggaggtgtcg atttctatct gacagagttc ggtgtaaaaa gaaacgagtc
     2461 tggtgtaagc tgcatgatgg aagtcttcta tttcctgaag ggtttcgggc aatgtctcat
     2521 ccggatggca tgcgcgtact atgattttca cgcccatccc tttggggctg ataaaggcga
     2581 tgcgggtgta atcgcatctc ttgatgatag ggaggatgcg tgccaattct tctttgctga
     2641 ggtggtcgat gtctatcacg atgtgtccca gatatttgac gaggttcact ttggtacgcc
     2701 ttcctcggta gctggcggag aaggcgattg ccggcaattc ttttttcttc tcattggcag
     2761 ccttttctcc ttgctctgca aagatgcggc gtatttcttc gactttttcc cggtaggtaa
     2821 aactgccgat agtggacact atttcttctt cggtcatctc tgctattgcg tagtagaaac
     2881 cttgaaatat ggtgaaatgt ttcattttta ttttgattat tgtttgtcga tgcaaaggaa
     2941 cttctttgcg gaaatgtgta aaggaacttt gtataaaatg gcaataagtt actacggttc
     3001 gcccaaaaag tgtatgatag ttgccacttg tttcggcgaa aggagacggt tgcgtgcgcg
     3061 gtagccttcc tgttcgagtt cgtgcaggag agggaggttg taaataatcc aacgacgaag
     3121 tatttgtaaa gcaactttga ggcagacatg gggattgtaa aggtgagcca gttccgcttt
     3181 ggtataggtg cggataagga aagaatcttc tttgtaattc atgatgtttt cttcttgttt
     3241 tatgctataa agttacataa aattccttgt tattcaaagg tttgacttcg tttttattcg
     3301 ttgggaatca agaaacttcg ttggggaata tggcttgtcc ggctatcctt atctttgtgc
     3361 tgttaacaag aaggggatgc atcctatgta ttataaactt taaaattatt ttattatggc
     3421 aatgacagta tcttattcag tggtgccgcg caagaatcct gcaaaaaaga gcgaaccggc
     3481 aaagtattat gcacaggcgc aggcgtcggg agagttggac tttgaagagt tgtgcgaagc
     3541 gatcaccagt cgttctactt gtacggaaac ggatgtacgt gcggctattt cgggtattct
     3601 ttacgaagtg aagcgtgcgt tgaaggcagg aagaattgcg agactgggcg atttgggcag
     3661 tttgcagata ggactcaaca gtgaaggtgc ggcatcggtc aaggaatttt ccggttcaat
     3721 gattaagggg gcgcatctta ttttccgccc cggtaagacg ctggcggagt tgatgaagat
     3781 tctgagttat cagcaagtgc agactcgtgc ggtggcgcag gcgggtgcag gcgatggcgg
     3841 gggagaagac cctgacaaga atccggattc cggtggtgat ggctccggtg atgaagaggc
     3901 tccggaccct acggtataat tggcagacgg gtcaaggtaa taacgaatta gaataacttc
     3961 cattaatatt ttgataagat gaaagaaata gtaagtcgga ttttagatgt gatcatgtat
     4021 ctgattcctt tcttcggaaa gagaaagcgg gacagggtgg tgagagaagt gcgctatcat
     4081 actacttgta aggaggtgtg caaagtgaaa acgacggaaa gggaaaagga acatgagaaa
     4141 gattagtctg attgtgatcc attgttccgc cacccgtgtc gattgcgact ttacggcaaa
     4201 ggatgtggat acggctcacc gttatcgtgg cttttcgtgc tgggggtatc attattatat
     4261 acgcaagtcg ggcgagattg agccgatgcg ggatgaagat acggtcggag ctcatgcacg
     4321 tggctataat gcgatcagct taggtgtatg ttatgagggc ggtctggatg agaatggaaa
     4381 agctgcggat acgcgtacac cccgtcagaa ggaggcgcta catcgcttgg tacacgaatt
     4441 gttgcagcgt tatccggaag ctaaagtagt agggcatcgg gatttaagtc ccgacaccaa
     4501 ctataatggg atcgtagatc cttgggaacg gattaaagaa tgcccttgct ttgaggtcat
     4561 tggagaattc tccattaatt aactaccacc gtagtgaaat actctttgaa tacctccgca
     4621 gctttttcaa gctgttcggg ggtattttct tttacccctt tcatcttgta ttcctgtccc
     4681 atcgcttcgt acttatgtac gcccagtgta tggtaaggca gtatttccac ccgttggatc
     4741 atcttgtatt ttccgagtgc ttctcccagt gcgcgtatgt cttcttcaaa atcgctgtat
     4801 ccgggcacta gcacgtagcg tagccagaaa ggtttctcct gttcttccag ccaggcggcc
     4861 gtgcggatgg tttgctcgtt gcttcttccg gtgagcgtct gatggcggtt ggggttgaat
     4921 tcctttatat ccaataacac aagatcggtc agtctgaata attcttctac gtcttcgttc
     4981 caaagtcctc cgttgctgtc cagacagaca tggatgcctt tttctttcag ttcgcggacc
     5041 agcgggacga gtgttttcgc ctgaaacgtc ggttcgcctc cggagaaagt gattcctcct
     5101 cgtttcccga agaaggggcg ctggctcatt gccatgcgga cgatttcttc cggtggggta
     5161 ggcgtgcctc cctttcctgc tatcgtatcc ggattggcgc aatagaggca gcggaagttg
     5221 catccttgaa gaaaaacgac gagccgtaag cccggcccgt cgaatgttcc catactttcg
     5281 tatgaatgta cgtttatcat catatagagt aatagattac atacgttcgt ggaagctacg
     5341 gctgataact tccagttggt gttcgcggct cagcttcacg aagtttacgg catagccgga
     5401 aacgcggata gtcagctgcg gatagttttc cggatgctcc atggcatcgt acagcatatc
     5461 acggttcagt acgtttacgt tcaggtggtg agcacctttg gtgaagtaac cgtccatcat
     5521 cgttacgagg ttctcgatac ggtcttcgtc cgtagcaccc agtgatttcg gaacgataga
     5581 gaaggtgttg ctgataccgt cctgtgagtc acggtaacga agtttcgcta cagagctcag
     5641 agaagcgatc gcaccattct tgtcgcgtcc gtgcatcggg ttggcacccg gagcgaaggc
     5701 aacacctttg gcacgtccgt cgggagtagc accggtcttt ttgccgtaca tcacattgga
     5761 agtgatagtc agcaaggaga gggtaggacg ggcattcttg taaactggca atttcttcaa
     5821 ttcttcgctg aagaagtata ccaggtctac gccaaggtgg tctaccttgt cgttgtcgtt
     5881 accgaagcaa gggaattctc cttcgatgtc gaaaccttct gtcaggccga tatcgttgcg
     5941 gcgggcagtt actttcgcat atttgatggc agacagtgaa tcgagggcga tggaaagtcc
     6001 ggctacaccg taagccaggt tgatgcgcgg gttcgtatct acaagagcca tctgggcctt
     6061 ctcgtagtaa tacttgtcgt gcatatagtg gatgatgttc atcgcttcgt tatatacgcg
     6121 ggcgatttcg gtcagcactt ttttgtagtt gtccattact tcttcgaact tcagcgtgtc
     6181 actggtcagt acggggatgt tcttcaccat gactgtaccg gtattctcgc aacgtccgcc
     6241 gttgatggca agcaacaggg ctttggccag gttgcaacgg gcaccgaaga actgaatctg
     6301 cttgcctatt tcctggtatg atacgcagca ggcgattccg tagtcgtcgg actgacgtac
     6361 ttcacgcatc aggtcgtcgt tttcgtactg gatagaagaa gtgtcgatag aaacctttgc
     6421 acagaattct ttgaatcctt ccggaagttc cgggctccag agtacggtca ggttcggttc
     6481 cggtgaaggg ccgaggttgt acaatgtctg cagaaaacgg aaggaggtct ttgtcacttt
     6541 ggtacgtccg tcgttgagac gtccgcccag agattcggtt acccaggtcg ggtcgcctgc
     6601 aaagatgtcg ttgtatgatt gcatacgcag gtggcggacc atacgcagtt tgatgacaaa
     6661 ctggtcgatc agctcttgcg cgaacgattc ggtgatggtt cctttgctca gttcatattc
     6721 cagatagata tcgaggaaag aagaaacgtt acccagtgac atagcggcac cgtcttgttc
     6781 tttgacggcg gcaaggtaag ccatatatac ccactgtacg gcttcttgtg ccgtgtaagc
     6841 gggacggctc aggtcgagac cgtagtattc gcccatcact ttcatgtctt tcagtgcctt
     6901 gatctgttct gccacttctt cgcgcaggcg gatgcgggcc tctgtcatcg gaccggtgag
     6961 gttgtgcaaa tcttccttct ttgcttcgat cagacggtcg atgccgtaaa gagccatacg
     7021 gcggtagtca ccgatgatgc gtccgcgtgc ataattgtcg ggaagtccgg taaggaatcc
     7081 cagcgaacgg aaggaacgga tttcttccgt atatacgtcg aatactccgt cgttgtgcgt
     7141 cttgcggtag tgagtgaaaa tatcttttac gcggtcgtcc acttccacgc cgttttcgtg
     7201 acaggctttg ctgactacgt tgatacctcc gaaaggcttg atggcacgtt tcagaagttc
     7261 gtctgtctgc aggccgacga tcagttcgtt ttccttgtcg atatatccgg ccttgtggga
     7321 agtgatggtt gatacggtaa cattatctaa tgagcggaca ccgttgtttt ctctttcttc
     7381 tgccagtgct tcgaggcagc ggttccatac ggctttggta cgttctgtag gtccttcgag
     7441 gaatgaagca tctccgtaat acggagtgat gttatgactt acgaaatctc tgacgttgat
     7501 ttcgctgctc caaagaccgt ctttaaagat cttgtttaat tccataaaat gataaaatta
     7561 gaggttgtag ttatcctatt ctttagagcg cacaaagtta caatcatttt tcatataatc
     7621 agcataaata tgctctattt tatgcttttc aacataaaat acctattaat tgctatcctt
     7681 aggaaaagat tagattaaat ttttagtgaa aactcttgca agtttaaaat atcttcgtac
     7741 ctttgcaccg cttttaacga aaagcacttc tgacaaggaa gttttggaga ggtggcagag
     7801 tggtcgattg cggcggtctt gaaaaccgtt gtaccgcgag gtacccgggg ttcgaatccc
     7861 tgtctctccg caataaacgc tgaaaatcag cagattgtaa aacaagcacc caattttaca
     7921 cccaagagtg taaaattggg tgcttttgta ttatttaaga tttatacttg aaaataggga
     7981 cacaaccaat gttattgggt aaaaatagag cattattatt gattaagttt attcaatcgc
     8041 ataacaattg acgtttgact tctgcccatt ttgtttgcaa tatatttgac gctcttaccc
     8101 tcattatgca gtttcaatag aaattggtct gcacttcttg tccatctttt attggcattg
     8161 gggtgcttca cataactctc ttctgaaacc ttttcaggat gcaaaaattc atccacaaat
     8221 acagagggga aacgcttgtc atatagcaca agagttttca tctttgccct tgttattgct
     8281 acataaaaca atctacgttc ttctccatat gggaattggt cgcttttagt tagtacatag
     8341 ttaagcacag ggtcgtcact cacaagagat gggaagccat aagtgtcttt attgcattgc
     8401 aagagtatta cgtaatctgc ttcaagacct ttcgatttat gtacagtcaa aaactcgatt
     8461 tttcgtcctc ctatcacata aaagaaccta ttgccctctt tgatggattg gtacataaaa
     8521 gagagataat aatcatcaaa ggaataacgt cccaacaaaa atattgattt gtctgatgga
     8581 atagaagcta caagttgccc tatcgtattg caataatcac gtctgtcata agaataaaac
     8641 tccaattctg ttttcatttc agaactgaac gagtgtatat ctttctgaat ttgtgattta
     8701 ttgcgttgta tgaaatgaga ggacaacgaa accaaaggtt ctccaaatct gtatgtggtt
     8761 tcaatcttat ttatttctgt tgctccaaag tattcggaga attgattgaa aagagccata
     8821 tcacttcccg aaaaacgata tatggactgc cagtcatcgc ctacgcaata caactttgct
     8881 ggtggatttc cctcacgcaa cacttttaaa aagttataac ggtcaacaga tatgtcttga
     8941 aactcgtcca cgatgatata atcatactca acaggacgtg aaacacgaca tatttctgtg
     9001 gcttgaagaa tcgcatcagt aaaatcaatt tggttattat ctcttaatgc gcttatatag
     9061 cgttcatata caggctggaa tatattcttg ataataaaaa cactccgttc atcctctgca
     9121 tacttcgctc gtttaagaac gtccttaact gatttacagc ttgatttcac taatgtcaca
     9181 aaagtaacaa caagtcgtat aaatgccttt tcctgcttac ttcctttggg taaaactaaa
     9241 tcatataact cttcatccgt tttctcttga attggtacac ctgcatcatc taatagttta
     9301 cggagtttat ccctaatatc agaataatgg aaatcagcac ttgatgttac taaaagttga
     9361 gtgccaaatt tctcatgagc tgctttcttc caagttatac catcattata tttttgattg
     9421 gcttcttcgt atgttatatt tttatccttt gcaaaccaag ctggaacaag accatgttca
     9481 tcaaccccga aatgctccag atagattcgt ttggttactc cattttgctc gaaatatatg
     9541 gaaaaatcgg ggcgatattg agagtgcatt tcatctgcca attgatgttc gtatgcctct
     9601 tcatatctga atcttactcc aagtgaagac aagacaaagc atatcttttg ctcttgctca
     9661 cttctcacat atatggctcg accatccata tcgggacaca ttgcttttaa ctgaacattt
     9721 ttttgttccg ataacttttc tcgcctttca ttcttgcgtt gctcccaatc cgcttcattg
     9781 gattgataat caataaaata ttctactata ctattcttaa aatccttatt ccctaataaa
     9841 gtgtgataaa tatctacgaa taaagaatca gtattatcgc aaatagatgg ttttgtgcct
     9901 gttgctcttc caataatatc aatggctaat ttatgaaaag tataaccttt caagccgtta
     9961 gtagccattc tttccgtaag ttcggctgct gctttgttcg tgtaactaat gagtaagatt
    10021 ctatgaggta caatgccttt tatttctgtt agatacttga cttttccaac aatagaagag
    10081 gtctttccac tacctgcgct actaacaacc aagcaattat cttcttctga aacgattgag
    10141 cgtctttgct gcttgtccaa tggatatttc aaacaatggt cgaaaaattc tttatgtgta
    10201 tcaagtaaag aatttataac cgcatcatta tgttgcttga caatcttatt gatattccca
    10261 aagtcacgaa ttaggtttga gattgctaca gatggagtga tattgaaggc ttcaagtctc
    10321 ttgactaatg aatgcgcctc ttgaaaatat ggtatataat gatttgtgaa atccttttct
    10381 tgcgttgcag agattatctt acatgaaaaa acattattaa ggtcggtcgg aatatcaata
    10441 aatgcttcgt tgtttaatgc cgacaatctc tcttttgctt gctcataatt ggatttattg
    10501 ctataagaag atatgtggtt taacttttct gaaagttcct tggacttgtt ttttaggcgt
    10561 attcgtattg tggctactgc aataacagaa atagcaacaa gagaaaccac aactataagt
    10621 aaaaccaact gcatatcaga ggatgatgac tatttaaatt tttcaatcca cctataatca
    10681 tcccccttgg tactccattg gaatttccac atgtcacctg tcctatcatt tataagatag
    10741 tattgataca tgcttgtcaa tggttgaata gagaatatac atttttcgtt atcggatcct
    10801 aattcgtctt tgtttatagg tatgcaaaat agattatcta aatcttgtgt gctatattgg
    10861 acttgccata gtcgtccatt atacgaatct aataatatga aagtccacat gttttgggtg
    10921 gcaaacatct gaaacctatt agtccaattt gaagttgctt cgggatatgc aagagagaag
    10981 atgttgattg gggcagcaaa catataatct tcacctttta cactaaattg aacttgccaa
    11041 tttttccctg tatatgtatc aagcattatg aaagtccaca tgttttgtgt ttcataaagg
    11101 caaaacctac tttccttatc tccagatatt tctcttgtac tacaaataat ccaagactga
    11161 ccatcatctt gtatttgctg cacttcacct gtcatcgtat ttaaacgaag ctggttatga
    11221 tagtttcgcg tactatacat tttataaact tgggcatacg atgccaacgt aataaccatc
    11281 aatgcaaatg atacaataag cttcttcata atttattata ttattggcta ttaattgatt
    11341 ttatttttca gggaataaac ttgacaatgc tcgtctaatg gcttggcgaa tatcatcagc
    11401 ttctgtttct ccttgcccct ctgccgtaca agagcatatc atttcattgg tttttgcaga
    11461 actaaattgt atggttactt ctattgtata gcctaaacct ctgttacgcc taccactctc
    11521 gccataattg acaattaagg tttcattcgc taattcggat ttgagttcag gcaatataat
    11581 atacccctgt tttatcaata ttcctgctat cacatcactc ggattaacac ttttggtagt
    11641 tgaagagcca tagataccat attgacctcc atatgtacct cctgtgcttg atgtcaattc
    11701 ctttgtcgga gaaatgtatg cgtatttata catttcaata ggagcattcc ttactattac
    11761 aggtgttcga agtggtgcac acccatttgc taatagaatg gtgcaaaaaa ctaatagcca
    11821 atttttaatt gcgttcatac actacacatt tatcctccag cttccacaaa ggatgggtta
    11881 aatcacgaag cgtggaactg tatgccacac tcttacttga aggtcgtagg aaaccttgga
    11941 tacggatgta acaatagcag cccacgctat agcgtgagaa ccactatgct atccttgtat
    12001 ccaatttgaa aatttcctac gttttcaagt acaagataag cataacgctt cttctttttt
    12061 cttatgtctt ggaaagagtt gcctcaatcc gcttacaaag atatttaatt ttattgagat
    12121 acaatcaaat actatcaaaa ttacattctg aaccctctac tttttcttgg ctcttccgca
    12181 gactgtcgca aaccttgcct taatttcttc cattgttcct tgaaccattc acctatcggt
    12241 tgtcggttta tggtcagcac caatttgtta tcatcgaccg gacttttctc cactttgaaa
    12301 acatcattct tgatttcaaa tcttcgtcta tgctcttcgg aataaatttt accattacac
    12361 ctgatagatt cttttttggt caaaagactg tttaccatgt ctttggtaaa tccgatagca
    12421 taacatagtt tttccattct caacatctct ttgagcaatg ggaaccagtt gaatgctttt
    12481 tcaagaatgg tgttcaatcg tgatatttcc ttgtctttgg tttcaagctc ttgattatgt
    12541 attccttgca ggttacgaat ctgcttgccg tgctgttcct gcatttgttg catcttggct
    12601 tttaattcat caataccctt gtcacgtttg gctatttcat gacgtaaatt ctcgttagat
    12661 tgttccaaat ctttcaattt accgctgccg aaaagagaac cgacaccact tgctatggcg
    12721 gtggctgcat cagtggctac acttttgagc ttgtcggtgc gtatctccga ttttacctgt
    12781 ttcagctcct gttcggcaaa gcttatttgt tgctccttgt gtcgtttggt ttcctctata
    12841 cgttgcagtt cagctttctg tttttcaatg ataaagtcgt ttcgctctaa atgctctttg
    12901 ccagtgacgg cctttgactg cccacgttcc attattagaa tgtcggatgc caagctctgc
    12961 atttcggtca tatcttcatc attaagtttt cggctttttc cggtttcgtg gttcatccag
    13021 tcgaaaacga tatgggcatg ataattcggt ttgaaccatc tttcgcctat ttggaaactc
    13081 tccctatctt cggcttcggg gtgtccgctc agccaatgcc cctcgtcctt gtgcaggaag
    13141 atttgaagcg gtgtgatgcc ccaacgcctt tggcactcct cgccgaattt acgcacgtca
    13201 gccagtgtgg tgtccggtct gacgagtaac actccctcac ggatggggga acatcccgcc
    13261 accttgatag tctttccatt ctttcccttg cgttcccttt ctttttcctg catggcacgt
    13321 ccggtctttt ccttgaccat tcgtttgacg ttgtcatagt gcgtccgcag ttcgggagtg
    13381 ccgaagtcgg gatttatcca ctgttcgtta tcggtggaaa gttcgggaac gacatagatt
    13441 ctggactccc cgatattacg catatactcg gcagcccttc ggttgtgcgc ctcgctcgat
    13501 gcgatgttgc aaggcttgat atgtatgctt gattttgttg ccataactat tctgttttta
    13561 ttgtttaaat tgattgcttt gctcgcttcc gcagaggggt tcttaggggg tgtaacccat
    13621 aagcggagat tgcaaagaga gggtcactct ttgctcgggg ttctcagggg tgaaacgccc
    13681 tgagtgggtc attagggcaa agccctaatc ccctcgggag agcccacaac tacgaaagcg
    13741 gagcgtgtag ttatagtggg ctataactga aagccgttct tctttttcgg tgactggctg
    13801 cgcgtctctt tgacagaccg gacttgcctt tttctttcaa cctgtttctg caagtattca
    13861 ttcaagtcct tgcatccgtt gtaagtctgc gaagcgtcac ggatgtacag gtctctgccg
    13921 tattccttgc ggatttgtcg gagagcttcc atgcctgcat ggtcgttgtc aaaaaagcag
    13981 tggatgcgtt cgtagctgcc caacggatag agagccttgt ttacattcga tacggagttc
    14041 aatacaatgt agtcctgtcc gtccaactcc ggataattcg ggcagctctc ctgtctcaat
    14101 gtcagaaagg agaggtagtc catgaatccc tcgaacacat aacaggtatt ccttgctttc
    14161 cccgactgcc tgatgtggga gatttccttg ggtgcgatgc aacccttgaa atagcggttg
    14221 cgaacctcaa atccacccga accattggga aaggcgatgg caaagtaccg tttgccattg
    14281 tgggtgaaac gggcttcact acattctctt tttgccagtt ccatatttat tcctcttccc
    14341 tgcaagtagg caagcagggc aggggacgat aacggaacaa tctccaactg ttggaaactc
    14401 ggttcggaag agttttgctt gccaaaagag aaagataccg ggcgcacatg cggtgtctgt
    14461 tccgctatcc gttttaaaat gtaaggtaca tggtcggtag catacaggtg tgcagccagt
    14521 tcaatgatac cgccaccttt gcccaaaccg aagtcatacc attggttacg ttcggtattt
    14581 atcttgaacg aagcttctgc ttcttccctt aacggtgatt tataccacag gttgatacct
    14641 tgttgcttga cgggagaata tcccaaactg tgcagaaaat ctgctatcct gatttgcttg
    14701 gctgtctgta tatccataaa atgattgttt tagtagttgg taaattggtt gctaaattga
    14761 ttcgtttttc ttttcgcccg taccatttta agaagtacgg tctgtataac cacttcactt
    14821 tattttcgta tatataggat acggtagtaa agtgaagtgg ttttgtactt cctgcaaccg
    14881 cttcgcttta ttcctaatat atagacccac agaataaagt gaagcgatta caaacaacag
    14941 gctaatagtg gaagtcgggc atgaacgtgt atttcctgcc gttctcctgc actatcatcc
    15001 gtttgttgcg aagcatggtg atgagcggta ccgccttttg atggttcagc tttacaccta
    15061 ttgacgtata gcttttgatt aaggcatttt ccagctcctt gtagccatat tcctctttca
    15121 gtccgaaaac cgcttccagt gcgatgcggt gctgttgttc ggtgatgtgc ctgtaagggt
    15181 caaacttttc ctcttccggc cttcccggtt tcttggcttc gggcttgtaa ccctccatga
    15241 gttcgggcag ggcattgtcg ttgatacgga atgcgaaagg ctcgaagtcc attgccctta
    15301 tgtgcatggc tgatacttta cttatatccc cgttgttctt gtccttttcc acaaggagta
    15361 cggtttctgc cttgttgttc agttcagtac cgatatgccc tctcgcattt tcatcccctt
    15421 tgttctgatg cagtatcgta tggatatgta tctgcctgtc gtccgtccac tgcatcagtt
    15481 tggatatgat gcgtgtggat tcgccggggc tgttgatgtc atataccata tcacgaatac
    15541 cgtctatgat tacaagggct atgttggggg tattgtagat agcctgctct gcaatcctga
    15601 tacgctgttc gggcgtgtat ttcctcaaag caagaaattc aagattttca ttgtccctgt
    15661 catcgggaag cccggccatc cgcaaaatac gtttcatgac tttcaggcaa tgataagggc
    15721 tttgttccgt gtccacataa aggattttcc gtttgtcttc cggaagttca gccacatatc
    15781 gcagcactgt gccgttcttc aatgcggcgg ctacgatagc cgacacattg aacgtctttt
    15841 tgctcttggc tttgccgatg gatgcactga aattccccaa tgtccctatg acggaaccat
    15901 gtactttgag aatctccggt gctttttcat aacttttcga caggctcaaa cgtgaggctt
    15961 gccaaaggat tacggcttct tctgccgata tttccttgtt gtctttcata taatccataa
    16021 gtacacctcc cgttattttc gtcctccggt tttctttccg gccagttcaa gggcaagttc
    16081 cgcatcaacg ataatcttgc gccctatttg cgtaatggct ttgtcaatct ttccgctttt
    16141 ctttatacgg ttggcggtgg gcaggctgca cccgaacagt ttggcaatgc ccggtattcc
    16201 gtacacatac ttcctttcca tgtccgtgat gggctgcggt tgcgcttccg tttggttgga
    16261 agcgtgcttg cttaggaata tgaactcttc gcctgtcatc tgccagacgg gttttaataa
    16321 taactcttga agatttgtca tcgtccaatc tatttagtcg ttaaactatc agccctgcgc
    16381 actggctgtt atctatgttc tcgaacgatg caaaattagg tagggttata agtggtaagg
    16441 atgtggttaa tgtaaatgga atgtcttatt attcatctga atatcagaga ataaaaatac
    16501 cactcaaaaa ttaatttgag tggtaaaagt ggtaatttca tggaatgtca ggatgtatca
    16561 cgaattatct gaatatgctt tccatttctt tggcgaattt ctggttgcta tcacttggaa
    16621 aatcggaaac gggttctttg tacttcgatc tgtaatagct ctcgtcaata tccagtagtt
    16681 tcaatatctt gtctcgccat tcgtccctgt attgcttgga tagtttttca ctcatcagga
    16741 atatcaggta acacacccgt atcttttccc ttgccttgat ttttaatctg ttcttgcagg
    16801 ggtacagatt tatattggca tagaagtccg ctatggtaat ggcttcgaac tgttccccga
    16861 cacaggtttc ataaataggc gaaagcggct tcatgtcaaa atattcatgc tgttcctccg
    16921 gtgtattctg tacttcttct tgcgcatttt gctcgactga ttcctccggt cgtttttctt
    16981 ccacatcatc aggaaggtat tttttcagga cttccatgaa aagaaggctt aggcggtaaa
    17041 catcactgga aaggttttcg atatattgaa aagcctcttt ctggtcttgc ttttgcagtt
    17101 catagagttt atccaattcc ttcttttcct tgtcgtattc agccttgcag cgttcatatt
    17161 ccttttctgc ctgtatttct tcttcgtccg tatgctcccg aaaaccaatg aaatcatatc
    17221 tgtggtatgc gtcattcaaa ggctcgtgca acttggtggt aatctccaac tggtctctaa
    17281 ttgcagaatt acgtctgtct gcgtagtgaa aacacacacg ctttatgatg tcatcattca
    17341 gcggttttgt ttcataagcc cgtatattct tttctatttc gatttttaaa ctattgagaa
    17401 tcaatgtgta ttgttcttta tgcttgtcaa gtaccagttc aaggatagcg gattcaaaag
    17461 cctttgtatc attgtgctgc ctgtaaaaat cggtgatgaa tttttgcttg tcaaaagaaa
    17521 aagcataatt ggtcacccaa tcatt
//
