## Fri May 2 14:16:22 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_019126635.1/GCA_019126635.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_019126635.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_019126635.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs BHPHKHDA_00001 326426.Bbr_1728 2.3e-186 519.0 COG5340@1|root,COG5340@2|Bacteria,2IDUY@201174|Actinobacteria,4D00E@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - BHPHKHDA_00002 326426.Bbr_1729 1.43e-169 476.0 COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,4CYSH@85004|Bifidobacteriales 201174|Actinobacteria K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - NusG BHPHKHDA_00003 326426.Bbr_1730 1.66e-42 139.0 COG0690@1|root,COG0690@2|Bacteria,2HZQC@201174|Actinobacteria,4D18K@85004|Bifidobacteriales 201174|Actinobacteria U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE BHPHKHDA_00005 326426.Bbr_1731 1.6e-291 795.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZFY@85004|Bifidobacteriales 201174|Actinobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family aspC - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 BHPHKHDA_00006 326426.Bbr_1732 1.56e-294 805.0 COG0726@1|root,COG0726@2|Bacteria 2|Bacteria G polysaccharide deacetylase - - - - - - - - - - - - CelD_N,DUF5011,Glyco_hydro_9,Polysacc_deac_1,SASA BHPHKHDA_00007 326426.Bbr_1733 2.92e-247 681.0 COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,4CZ2B@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA BHPHKHDA_00008 326426.Bbr_1734 0.0 1087.0 COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,4CYWD@85004|Bifidobacteriales 201174|Actinobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 BHPHKHDA_00009 326426.Bbr_1735 1.44e-51 162.0 COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4D19N@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal L27 protein rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 BHPHKHDA_00010 326426.Bbr_1736 1.01e-62 192.0 COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,4D10B@85004|Bifidobacteriales 201174|Actinobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p BHPHKHDA_00011 326426.Bbr_1737 0.0 1249.0 COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4CYQT@85004|Bifidobacteriales 201174|Actinobacteria J Ribonuclease E/G family rne - 3.1.26.12 ko:K08300,ko:K08301 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - IF2_N,RNase_E_G,S1 BHPHKHDA_00012 326426.Bbr_1738 7.01e-293 799.0 COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,4CZ9K@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase dimerisation domain dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 BHPHKHDA_00013 326426.Bbr_1739 1.58e-213 591.0 COG0679@1|root,COG0679@2|Bacteria,2GNIA@201174|Actinobacteria,4CZFX@85004|Bifidobacteriales 201174|Actinobacteria S Transporter, auxin efflux carrier (AEC) family protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans BHPHKHDA_00014 326426.Bbr_1740 1.72e-213 589.0 COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales 201174|Actinobacteria EM Dihydrodipicolinate synthetase family - - 4.1.2.28 ko:K22397 ko00040,map00040 - R01782 RC00307,RC00572 ko00000,ko00001,ko01000 - - - DHDPS BHPHKHDA_00015 326426.Bbr_1741 1.15e-190 528.0 COG3618@1|root,COG3618@2|Bacteria,2HRH9@201174|Actinobacteria,4CZX0@85004|Bifidobacteriales 201174|Actinobacteria S Amidohydrolase - - - ko:K07046 ko00051,ko01120,map00051,map01120 - R10689 RC00537 ko00000,ko00001,ko01000 - - - Amidohydro_2 BHPHKHDA_00016 216816.GS08_09520 9.55e-271 744.0 COG0738@1|root,COG0738@2|Bacteria,2GJ5D@201174|Actinobacteria,4D02K@85004|Bifidobacteriales 201174|Actinobacteria G Major Facilitator Superfamily fucP - - ko:K02429 - - - - ko00000,ko02000 2.A.1.7 - - MFS_1 BHPHKHDA_00017 216816.GS08_09525 5.27e-191 530.0 COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CZXI@85004|Bifidobacteriales 201174|Actinobacteria IQ KR domain - - 1.1.1.100,1.1.1.413 ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671 RC00029,RC00066,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 BHPHKHDA_00018 216816.GS08_09530 0.0 865.0 COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales 201174|Actinobacteria M Enolase C-terminal domain-like - - 4.2.1.68 ko:K18334 ko00051,ko01120,map00051,map01120 - R03688 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N BHPHKHDA_00019 326426.Bbr_1745 4.75e-245 673.0 COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, lacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BHPHKHDA_00020 216816.GS08_09540 1.24e-281 777.0 COG0577@1|root,COG0577@2|Bacteria,2GKF3@201174|Actinobacteria,4D03X@85004|Bifidobacteriales 201174|Actinobacteria V Efflux ABC transporter, permease protein - - - - - - - - - - - - FtsX BHPHKHDA_00021 326426.Bbr_1747 3.52e-166 468.0 COG1136@1|root,COG1136@2|Bacteria,2GM25@201174|Actinobacteria,4D0FV@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00022 1437608.BBIA_1347 1.21e-38 131.0 2B12Y@1|root,30DWC@2|Bacteria,2GWJ2@201174|Actinobacteria,4D1TU@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1778) - - - - - - - - - - - - DUF1778 BHPHKHDA_00023 326426.Bbr_1748 6.46e-116 332.0 COG0454@1|root,COG0454@2|Bacteria,2IC6K@201174|Actinobacteria,4D0SR@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 BHPHKHDA_00024 326426.Bbr_1749 0.0 926.0 COG0424@1|root,COG1051@1|root,COG0424@2|Bacteria,COG1051@2|Bacteria,2GNI0@201174|Actinobacteria,4CZXF@85004|Bifidobacteriales 201174|Actinobacteria DF Maf-like protein maf GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K06287 - - - - ko00000 - - - Maf,NUDIX BHPHKHDA_00025 216816.GS08_09565 1.23e-233 647.0 COG0083@1|root,COG0083@2|Bacteria,2GKIW@201174|Actinobacteria,4CZN0@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N BHPHKHDA_00026 326426.Bbr_1751 1.31e-302 827.0 COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4CZVD@85004|Bifidobacteriales 201174|Actinobacteria E Homoserine dehydrogenase hom GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00017,M00018,M00526,M00527 R00480,R01773,R01775 RC00002,RC00043,RC00087 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1294 ACT,Homoserine_dh,NAD_binding_3 BHPHKHDA_00027 1437608.BBIA_0273 1.49e-294 811.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,2GKPM@201174|Actinobacteria,4D069@85004|Bifidobacteriales 201174|Actinobacteria G phosphotransferase system, EIIB nagE - 2.7.1.193 ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 M00267 R05199 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BHPHKHDA_00028 702459.BBPR_0239 5.66e-75 228.0 COG2190@1|root,COG2190@2|Bacteria,2INQB@201174|Actinobacteria,4D11R@85004|Bifidobacteriales 201174|Actinobacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 - - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1 BHPHKHDA_00029 326426.Bbr_1753 0.0 1045.0 COG0019@1|root,COG0019@2|Bacteria,2GKAI@201174|Actinobacteria,4CYRG@85004|Bifidobacteriales 201174|Actinobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC BHPHKHDA_00030 326426.Bbr_1754 0.0 1216.0 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CZ9J@85004|Bifidobacteriales 201174|Actinobacteria J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d BHPHKHDA_00031 326426.Bbr_1755 4.49e-169 472.0 COG1309@1|root,COG1309@2|Bacteria,2HZJX@201174|Actinobacteria,4D0QJ@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N BHPHKHDA_00032 326426.Bbr_1756 1.99e-282 774.0 COG2271@1|root,COG2271@2|Bacteria,2HZ9S@201174|Actinobacteria,4CZ4Z@85004|Bifidobacteriales 201174|Actinobacteria G Transmembrane secretion effector - - - - - - - - - - - - MFS_1 BHPHKHDA_00033 326426.Bbr_1757 0.0 884.0 COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CZN7@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase BHPHKHDA_00034 326426.Bbr_1758 0.0 884.0 COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4CZXP@85004|Bifidobacteriales 201174|Actinobacteria C Pyridine nucleotide-disulphide oxidoreductase nox - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim,Reductase_C BHPHKHDA_00035 326426.Bbr_1759 2.62e-201 557.0 COG0834@1|root,COG0834@2|Bacteria,2IBGH@201174|Actinobacteria,4D2UM@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K16957 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - SBP_bac_3 BHPHKHDA_00036 326426.Bbr_1760 8.62e-155 435.0 COG0765@1|root,COG0765@2|Bacteria,2IJQ6@201174|Actinobacteria,4D2SQ@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K16958 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 BHPHKHDA_00037 326426.Bbr_1761 1.55e-178 498.0 COG0765@1|root,COG0765@2|Bacteria,2IH6I@201174|Actinobacteria,4D1A4@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K16959 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 BHPHKHDA_00038 326426.Bbr_1762 1.68e-132 375.0 299ND@1|root,2ZWQQ@2|Bacteria,2IPBZ@201174|Actinobacteria,4D26W@85004|Bifidobacteriales 201174|Actinobacteria S L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - - - - - - - - - - ATC_hydrolase BHPHKHDA_00039 326426.Bbr_1763 9.29e-169 472.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZTF@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities - - - ko:K10010,ko:K16960 ko02010,map02010 M00234,M00585 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 - - ABC_tran BHPHKHDA_00040 326426.Bbr_1764 2.51e-281 768.0 COG0167@1|root,COG0167@2|Bacteria,2GJMN@201174|Actinobacteria,4CZKM@85004|Bifidobacteriales 201174|Actinobacteria F Dihydroorotate dehydrogenase pyr - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh BHPHKHDA_00041 1437608.BBIA_0331 3.71e-47 171.0 COG4585@1|root,COG4585@2|Bacteria,2IC0A@201174|Actinobacteria,4D04K@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - - BHPHKHDA_00042 1437609.BCAL_1446 1.31e-17 88.2 COG3428@1|root,COG3428@2|Bacteria,2HZEK@201174|Actinobacteria,4D032@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial PH domain - - - ko:K08981 - - - - ko00000 - - - bPH_2 BHPHKHDA_00043 326426.Bbr_1766 1.9e-170 475.0 COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,4CZ2F@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C BHPHKHDA_00044 326426.Bbr_1767 0.0 932.0 COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4CYUC@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase BHPHKHDA_00045 326426.Bbr_1768 2.37e-181 506.0 COG1414@1|root,COG1414@2|Bacteria,2GKB0@201174|Actinobacteria,4CZ9D@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, IclR family, C-terminal domain protein ltbR - - - - - - - - - - - HTH_IclR,IclR BHPHKHDA_00046 326426.Bbr_1769 0.0 882.0 COG1409@1|root,COG1409@2|Bacteria,2HRDZ@201174|Actinobacteria,4CYQR@85004|Bifidobacteriales 201174|Actinobacteria S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos BHPHKHDA_00047 326426.Bbr_1770 0.0 1467.0 COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4CYXH@85004|Bifidobacteriales 201174|Actinobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N BHPHKHDA_00048 326426.Bbr_1771 5.47e-314 858.0 COG0494@1|root,COG2062@1|root,COG0494@2|Bacteria,COG2062@2|Bacteria,2GNRV@201174|Actinobacteria,4CZ90@85004|Bifidobacteriales 201174|Actinobacteria LT Phosphoglycerate mutase family mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - His_Phos_1,NUDIX BHPHKHDA_00049 326426.Bbr_1772 2.83e-175 491.0 28MMU@1|root,2ZAXG@2|Bacteria,2HAD5@201174|Actinobacteria,4CZ1Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00050 326426.Bbr_1775 0.0 1269.0 COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4D0HI@85004|Bifidobacteriales 201174|Actinobacteria G N-terminal domain of (some) glycogen debranching enzymes - - - - - - - - - - - - GDE_C,GDE_N_bis BHPHKHDA_00051 326426.Bbr_1776 8.49e-66 200.0 COG0395@1|root,COG0395@2|Bacteria,2GITV@201174|Actinobacteria,4CZHG@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00052 326426.Bbr_1777 9.47e-151 424.0 COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4CYVS@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - - UPRTase BHPHKHDA_00053 216816.GS08_09655 1.05e-107 310.0 COG1576@1|root,COG1576@2|Bacteria,2IJE0@201174|Actinobacteria,4D0P5@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase BHPHKHDA_00054 326426.Bbr_1779 2.57e-274 749.0 COG0584@1|root,COG0584@2|Bacteria,2GNM5@201174|Actinobacteria,4CYS4@85004|Bifidobacteriales 201174|Actinobacteria C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,Laminin_G_3 BHPHKHDA_00055 326426.Bbr_1780 1.68e-277 757.0 COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,4CYRY@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family gluQ - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c BHPHKHDA_00057 326426.Bbr_1781 0.0 1655.0 COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4CZDY@85004|Bifidobacteriales 201174|Actinobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N BHPHKHDA_00058 326426.Bbr_1782 6.94e-210 581.0 COG0679@1|root,COG0679@2|Bacteria,2GN0R@201174|Actinobacteria,4CZ6C@85004|Bifidobacteriales 201174|Actinobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans BHPHKHDA_00059 326426.Bbr_1783 7.26e-203 560.0 COG0179@1|root,COG0179@2|Bacteria,2GN2G@201174|Actinobacteria,4CZH5@85004|Bifidobacteriales 201174|Actinobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - DUF2437,FAA_hydrolase BHPHKHDA_00060 216816.GS08_09695 5.17e-162 454.0 2EGCD@1|root,33A46@2|Bacteria,2I2HS@201174|Actinobacteria,4D1EH@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4190) - - - - - - - - - - - - DUF4190 BHPHKHDA_00061 326426.Bbr_1785 3.44e-216 597.0 2BG3R@1|root,32A0B@2|Bacteria,2IR5J@201174|Actinobacteria,4D1AV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00062 326426.Bbr_1786 3.28e-297 809.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 201174|Actinobacteria M UDP-galactopyranose mutase glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - iNJ661.Rv3809c GLF,NAD_binding_8 BHPHKHDA_00063 1437610.BREU_1204 3.16e-82 247.0 COG3311@1|root,COG3311@2|Bacteria,2IQFY@201174|Actinobacteria,4D15C@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_17 BHPHKHDA_00064 1437608.BBIA_2250 9.2e-10 58.9 COG1569@1|root,COG1569@2|Bacteria,2IMP1@201174|Actinobacteria,4D13G@85004|Bifidobacteriales 201174|Actinobacteria S PIN domain - - - - - - - - - - - - PIN_3 BHPHKHDA_00065 428125.CLOLEP_00679 1.86e-59 192.0 COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,25A7T@186801|Clostridia,3WRAW@541000|Ruminococcaceae 1239|Firmicutes G sugar phosphate isomerase involved in capsule formation hxlB - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS BHPHKHDA_00066 411468.CLOSCI_01968 7e-70 229.0 COG1172@1|root,COG1172@2|Bacteria,1V3BR@1239|Firmicutes,249XT@186801|Clostridia,220P8@1506553|Lachnoclostridium 186801|Clostridia G Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 BHPHKHDA_00067 592026.GCWU0000282_002492 6.17e-97 297.0 COG1172@1|root,COG1172@2|Bacteria,1V20A@1239|Firmicutes,247TN@186801|Clostridia 186801|Clostridia P branched-chain amino acid ABC transporter, permease protein - - - - - - - - - - - - BPD_transp_2 BHPHKHDA_00068 411468.CLOSCI_01966 7.71e-144 429.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,24CJF@186801|Clostridia,21Z5E@1506553|Lachnoclostridium 186801|Clostridia G ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran BHPHKHDA_00069 1122962.AULH01000016_gene124 1.04e-97 299.0 COG1879@1|root,COG1879@2|Bacteria,1MUAT@1224|Proteobacteria,2U2VQ@28211|Alphaproteobacteria 1224|Proteobacteria G ABC-type sugar transport system periplasmic component - - - - - - - - - - - - Peripla_BP_4 BHPHKHDA_00070 585198.HMPREF0574_1384 5.5e-211 599.0 COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4D3F4@85005|Actinomycetales 201174|Actinobacteria G Belongs to the FGGY kinase family xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N BHPHKHDA_00071 548479.HMPREF0573_10533 5.72e-90 286.0 COG1940@1|root,COG1940@2|Bacteria,2GJIE@201174|Actinobacteria,4D4U2@85005|Actinomycetales 201174|Actinobacteria GK ROK family xylR - - - - - - - - - - - HTH_IclR,MarR_2,ROK BHPHKHDA_00072 326426.Bbr_1785 2.37e-58 191.0 2BG3R@1|root,32A0B@2|Bacteria,2IR5J@201174|Actinobacteria,4D1AV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00074 326426.Bbr_1613 4.24e-217 599.0 COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CZ8H@85004|Bifidobacteriales 201174|Actinobacteria J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 BHPHKHDA_00075 326426.Bbr_1612 0.0 1448.0 COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,2GN0J@201174|Actinobacteria,4D061@85004|Bifidobacteriales 201174|Actinobacteria S A circularly permuted ATPgrasp gcs2 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06048 - - - - ko00000,ko01000 - - - Alpha-E,CP_ATPgrasp_1,CP_ATPgrasp_2,GCS2 BHPHKHDA_00076 326426.Bbr_1611 1.4e-192 534.0 COG1305@1|root,COG1305@2|Bacteria,2GN5D@201174|Actinobacteria,4CZBJ@85004|Bifidobacteriales 201174|Actinobacteria E Transglutaminase/protease-like homologues - - - - - - - - - - - - Bact_transglu_N,Transglut_core BHPHKHDA_00078 216816.GS08_08925 5.17e-126 369.0 COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D040@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_00079 326426.Bbr_1609 2.76e-162 455.0 2B54U@1|root,31XYD@2|Bacteria,2HXKT@201174|Actinobacteria,4D0IH@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00080 326426.Bbr_1608 7.22e-240 660.0 COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CYTW@85004|Bifidobacteriales 201174|Actinobacteria K Participates in both transcription termination and antitermination nusA GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 BHPHKHDA_00081 326426.Bbr_1607 0.0 1551.0 COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,4CZ4B@85004|Bifidobacteriales 201174|Actinobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N BHPHKHDA_00082 326426.Bbr_1606 8.26e-106 306.0 COG0858@1|root,COG0858@2|Bacteria,2IKXP@201174|Actinobacteria,4CZZZ@85004|Bifidobacteriales 201174|Actinobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA BHPHKHDA_00083 326426.Bbr_1605 6.66e-281 768.0 COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,4CZED@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB_C,TruB_C_2,TruB_N BHPHKHDA_00084 326426.Bbr_1604 2.91e-278 759.0 COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4CYXT@85004|Bifidobacteriales 201174|Actinobacteria H riboflavin kinase ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase BHPHKHDA_00085 326426.Bbr_1603 0.0 954.0 COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4CZE1@85004|Bifidobacteriales 201174|Actinobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI,Lon_C BHPHKHDA_00086 326426.Bbr_1602 6.83e-132 375.0 2EHBK@1|root,33B3F@2|Bacteria,2ICD4@201174|Actinobacteria,4CZY5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00087 1147128.BAST_1307 5.05e-07 46.6 29UT5@1|root,30G5G@2|Bacteria,2GXCZ@201174|Actinobacteria,4D1N2@85004|Bifidobacteriales 201174|Actinobacteria S Mitochondrial domain of unknown function (DUF1713) - - - - - - - - - - - - DUF1713 BHPHKHDA_00088 326426.Bbr_1600 4.47e-163 456.0 COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A BHPHKHDA_00089 326426.Bbr_1599 6.4e-241 664.0 COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4CZGC@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF4440,RNase_H BHPHKHDA_00090 326426.Bbr_1598 0.0 956.0 COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4CZZF@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - 1.16.1.1 ko:K00520,ko:K21739 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim BHPHKHDA_00091 326426.Bbr_1597 1.74e-96 281.0 COG1959@1|root,COG1959@2|Bacteria,2IKDG@201174|Actinobacteria,4D0YZ@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - Rrf2 BHPHKHDA_00092 326426.Bbr_1596 5.41e-253 694.0 COG2852@1|root,COG2852@2|Bacteria,2HTNX@201174|Actinobacteria,4D0CP@85004|Bifidobacteriales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - - BHPHKHDA_00093 326426.Bbr_1595 0.0 1132.0 COG0033@1|root,COG0033@2|Bacteria,2H1PI@201174|Actinobacteria,4CZ7X@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV BHPHKHDA_00094 326426.Bbr_1594 0.0 1251.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,2GK6B@201174|Actinobacteria,4CZR7@85004|Bifidobacteriales 201174|Actinobacteria G pts system, glucose-specific IIABC component ptsG - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC BHPHKHDA_00095 326426.Bbr_1593 1.58e-209 579.0 COG3711@1|root,COG3711@2|Bacteria,2I8K8@201174|Actinobacteria,4D08T@85004|Bifidobacteriales 201174|Actinobacteria K CAT RNA binding domain arbG - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD,PTS-HPr BHPHKHDA_00096 326426.Bbr_1592 2.49e-265 729.0 COG1597@1|root,COG1597@2|Bacteria,2GJ3K@201174|Actinobacteria,4CYTC@85004|Bifidobacteriales 201174|Actinobacteria I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat BHPHKHDA_00097 326426.Bbr_1591 2.27e-307 838.0 COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,4CZ40@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b BHPHKHDA_00099 326426.Bbr_1590 0.0 867.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CZ88@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 BHPHKHDA_00100 326426.Bbr_1589 3.93e-223 616.0 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZX2@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00101 326426.Bbr_1588 5.76e-217 600.0 COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CYV5@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00102 326426.Bbr_1587 0.0 1560.0 COG5426@1|root,COG5426@2|Bacteria,2GN2A@201174|Actinobacteria,4CYZB@85004|Bifidobacteriales 201174|Actinobacteria S Lacto-N-biose phosphorylase C-terminal domain gnpA - 2.4.1.211 ko:K15533 - - - - ko00000,ko01000 - - - LBP_C,LBP_M,Lact_bio_phlase BHPHKHDA_00103 326426.Bbr_1586 1.15e-259 711.0 COG2334@1|root,COG2334@2|Bacteria,2I8JD@201174|Actinobacteria,4D06K@85004|Bifidobacteriales 201174|Actinobacteria S Phosphotransferase enzyme family - - 2.7.1.162 ko:K13059 - - R08962 RC00002,RC00078 ko00000,ko01000 - - - APH BHPHKHDA_00104 326426.Bbr_1585 3.09e-224 620.0 COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,4CZDB@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd BHPHKHDA_00105 326426.Bbr_1584 2.47e-153 431.0 COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4CZW8@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon tcsR3 - - - - - - - - - - - GerE,Response_reg BHPHKHDA_00106 326426.Bbr_1583 3.31e-300 820.0 COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4CZ2U@85004|Bifidobacteriales 201174|Actinobacteria KT PspC domain tcsS3 - - - - - - - - - - - HATPase_c,HATPase_c_2,PspC BHPHKHDA_00107 326426.Bbr_1582 0.0 1040.0 COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria,4CZZT@85004|Bifidobacteriales 201174|Actinobacteria KT PspC domain pspC - - - - - - - - - - - DUF2154,PspC BHPHKHDA_00108 326426.Bbr_1581 7.82e-105 310.0 2BIES@1|root,32CM6@2|Bacteria,2GSGC@201174|Actinobacteria,4D1KF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00109 326426.Bbr_1580 0.0 1083.0 COG1073@1|root,COG1073@2|Bacteria,2H036@201174|Actinobacteria,4CYRR@85004|Bifidobacteriales 201174|Actinobacteria S alpha beta - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Hydrolase_4,Peptidase_S9 BHPHKHDA_00110 326426.Bbr_1579 1.83e-142 402.0 2DM2Z@1|root,31HGC@2|Bacteria,2GKMX@201174|Actinobacteria,4CZJ9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4125) - - - - - - - - - - - - DUF4125 BHPHKHDA_00111 326426.Bbr_1578 0.0 1373.0 COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4CZTS@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4037) - - - - - - - - - - - - DUF4037,TPR_12 BHPHKHDA_00112 326426.Bbr_1577 3.82e-276 756.0 COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZ46@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K08156,ko:K19577 - - - - ko00000,ko02000 2.A.1.2.14,2.A.1.2.65 - - MFS_1 BHPHKHDA_00114 216816.GS08_08675 0.0 1084.0 COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,4CZHM@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family lysS GO:0008150,GO:0040007 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon BHPHKHDA_00115 326426.Bbr_1575 2.77e-222 613.0 COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,4CZHQ@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the MenA family. Type 1 subfamily menA GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA BHPHKHDA_00116 326426.Bbr_1574 3.9e-178 496.0 COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4CZMF@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 BHPHKHDA_00117 326426.Bbr_1573 1.55e-150 424.0 COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4CZ9B@85004|Bifidobacteriales 201174|Actinobacteria P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0016020,GO:0019220,GO:0019222,GO:0022611,GO:0031323,GO:0031324,GO:0032502,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042221,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0045936,GO:0046677,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:0071944,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU BHPHKHDA_00118 326426.Bbr_1572 1.68e-234 651.0 COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZIM@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein senX3 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 ko:K07768 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA BHPHKHDA_00119 216816.GS08_08650 2.3e-44 144.0 2EG1H@1|root,339TH@2|Bacteria,2IQTR@201174|Actinobacteria,4D16E@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF2530 BHPHKHDA_00120 326426.Bbr_1570 1.6e-268 735.0 COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,4CZ94@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 BHPHKHDA_00121 326426.Bbr_1569 2.08e-216 598.0 COG3942@1|root,COG3942@2|Bacteria,2GP2A@201174|Actinobacteria,4CYXV@85004|Bifidobacteriales 201174|Actinobacteria S CHAP domain - - - - - - - - - - - - CHAP BHPHKHDA_00122 326426.Bbr_1568 1.3e-141 403.0 COG0791@1|root,COG0791@2|Bacteria,2IBQZ@201174|Actinobacteria,4CYXI@85004|Bifidobacteriales 201174|Actinobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60 BHPHKHDA_00123 326426.Bbr_1567 1.08e-142 405.0 COG0791@1|root,COG0791@2|Bacteria,2GJX7@201174|Actinobacteria,4D01Q@85004|Bifidobacteriales 201174|Actinobacteria M NlpC/P60 family - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,PG_binding_1,SLT BHPHKHDA_00124 326426.Bbr_1566 2.25e-240 661.0 COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4CZ6V@85004|Bifidobacteriales 201174|Actinobacteria T Universal stress protein family - - - - - - - - - - - - Usp BHPHKHDA_00125 326426.Bbr_1565 1.85e-95 278.0 COG1765@1|root,COG1765@2|Bacteria,2IIK7@201174|Actinobacteria,4D0PB@85004|Bifidobacteriales 201174|Actinobacteria O OsmC-like protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - OsmC BHPHKHDA_00126 216816.GS08_08615 8.56e-215 592.0 COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,4CZQ3@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt BHPHKHDA_00127 326426.Bbr_1563 1.2e-161 452.0 COG0262@1|root,COG0262@2|Bacteria,2IM1S@201174|Actinobacteria,4CZM1@85004|Bifidobacteriales 201174|Actinobacteria H dihydrofolate reductase folA GO:0000166,GO:0003674,GO:0003824,GO:0004146,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070401,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2763c DHFR_1 BHPHKHDA_00128 326426.Bbr_1562 3.01e-127 361.0 COG0394@1|root,COG0394@2|Bacteria,2IM0Q@201174|Actinobacteria,4CZWM@85004|Bifidobacteriales 201174|Actinobacteria T low molecular weight ptpA GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0035335,GO:0035821,GO:0036211,GO:0042578,GO:0043170,GO:0043207,GO:0043412,GO:0044003,GO:0044046,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052046,GO:0052047,GO:0052048,GO:0052083,GO:0052155,GO:0052173,GO:0052200,GO:0052212,GO:0052255,GO:0052278,GO:0052294,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:0140096,GO:1901564 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc BHPHKHDA_00129 326426.Bbr_1560 9.79e-143 403.0 COG1136@1|root,COG1136@2|Bacteria,2I7UV@201174|Actinobacteria,4CZ1C@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein vex - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00130 326426.Bbr_1559 5.09e-266 731.0 COG0577@1|root,COG0577@2|Bacteria,2IA7B@201174|Actinobacteria,4CZJM@85004|Bifidobacteriales 201174|Actinobacteria V Efflux ABC transporter, permease protein - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BHPHKHDA_00131 702459.BBPR_1469 1.03e-287 790.0 COG0577@1|root,COG0577@2|Bacteria,2I99G@201174|Actinobacteria,4D0H6@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BHPHKHDA_00132 77635.BISU_2462 7.34e-12 65.1 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2GKW1@201174|Actinobacteria,4CYXY@85004|Bifidobacteriales 201174|Actinobacteria L HTH-like domain - - - - - - - - - - - - HTH_21,rve,rve_2 BHPHKHDA_00133 326426.Bbr_1556 0.0 1368.0 COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 20, domain 2 - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b BHPHKHDA_00134 326426.Bbr_1555 1.83e-278 761.0 COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4CZUF@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - Crp,HTH_24,ROK BHPHKHDA_00135 326426.Bbr_1554 3.96e-310 846.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4D0C5@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_00136 216816.GS08_07340 5.83e-28 106.0 COG2826@1|root,COG2826@2|Bacteria,2H4CW@201174|Actinobacteria,4D25Y@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_38 BHPHKHDA_00137 326426.Bbr_1553 2.07e-236 650.0 COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BHPHKHDA_00138 326426.Bbr_1552 0.0 2158.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 lacZ6 - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3 BHPHKHDA_00140 326426.Bbr_0356 1.27e-291 796.0 COG1373@1|root,COG1373@2|Bacteria,2I96U@201174|Actinobacteria,4CZD7@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_00141 216816.GS08_00470 4.3e-259 712.0 COG0477@1|root,COG2814@2|Bacteria,2HZWA@201174|Actinobacteria,4D211@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_00142 158787.BSCA_0159 1.81e-39 134.0 COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales 201174|Actinobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2 BHPHKHDA_00143 158787.BSCA_0159 3.76e-17 76.3 COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales 201174|Actinobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2 BHPHKHDA_00144 216816.GS08_01565 2.34e-135 386.0 COG1309@1|root,COG1309@2|Bacteria,2I8SX@201174|Actinobacteria,4CZXQ@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N BHPHKHDA_00145 326426.Bbr_0358 0.0 884.0 COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2974 BHPHKHDA_00146 326426.Bbr_0359 9.62e-116 331.0 COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4D10F@85004|Bifidobacteriales 201174|Actinobacteria L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated ogt - 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N BHPHKHDA_00147 326426.Bbr_0360 6.4e-106 306.0 COG0736@1|root,COG0736@2|Bacteria,2HZNB@201174|Actinobacteria,4D10J@85004|Bifidobacteriales 201174|Actinobacteria I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - - ACPS BHPHKHDA_00148 326426.Bbr_0361 1.35e-94 276.0 COG0366@1|root,COG0366@2|Bacteria,2GKT9@201174|Actinobacteria,4CYRW@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain ams - 2.4.1.4 ko:K05341 ko00500,map00500 - R01823 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase BHPHKHDA_00149 326426.Bbr_0362 2.07e-145 412.0 COG0475@1|root,COG0475@2|Bacteria,2GIRC@201174|Actinobacteria,4CZGM@85004|Bifidobacteriales 201174|Actinobacteria P Sodium/hydrogen exchanger family - - - - - - - - - - - - Na_H_Exchanger BHPHKHDA_00152 326426.Bbr_0363 5.1e-126 359.0 2C89M@1|root,332IE@2|Bacteria,2IPVJ@201174|Actinobacteria,4D133@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00153 216816.GS08_09350 0.0 1738.0 COG1361@1|root,COG1361@2|Bacteria,2GYAW@201174|Actinobacteria,4D2X8@85004|Bifidobacteriales 201174|Actinobacteria M Conserved repeat domain - - - - - - - - - - - - DUF11,FctA,VWA,VWA_2 BHPHKHDA_00154 326426.Bbr_0366 0.0 958.0 COG4932@1|root,COG4932@2|Bacteria,2GP68@201174|Actinobacteria,4CZV4@85004|Bifidobacteriales 201174|Actinobacteria M LPXTG cell wall anchor motif - - - - - - - - - - - - GramPos_pilinBB,Gram_pos_anchor BHPHKHDA_00156 326426.Bbr_0368 2.87e-112 322.0 2DNNA@1|root,32Y8E@2|Bacteria,2ISEY@201174|Actinobacteria,4D1A0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00157 326426.Bbr_0369 6.46e-145 410.0 2B37S@1|root,31VVT@2|Bacteria,2IDBE@201174|Actinobacteria,4CZJV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00158 326426.Bbr_0370 2.04e-56 175.0 COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D10E@85004|Bifidobacteriales 201174|Actinobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 BHPHKHDA_00159 326426.Bbr_0371 0.0 1509.0 COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CYSW@85004|Bifidobacteriales 201174|Actinobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 BHPHKHDA_00160 326426.Bbr_0374 4.3e-120 345.0 COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales 201174|Actinobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA BHPHKHDA_00161 326426.Bbr_0375 0.0 1410.0 COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 BHPHKHDA_00162 1680.BADO_0270 1.21e-14 74.7 COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 BHPHKHDA_00163 326426.Bbr_0376 7.26e-72 231.0 COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 BHPHKHDA_00164 326426.Bbr_0376 1.67e-84 263.0 COG4907@1|root,COG4907@2|Bacteria,2HZD2@201174|Actinobacteria,4CZV5@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 BHPHKHDA_00165 326426.Bbr_0376a 1.42e-28 102.0 29W0J@1|root,30HIU@2|Bacteria,2HBEV@201174|Actinobacteria,4D2JK@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00166 326426.Bbr_0377 2.87e-216 595.0 COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZB6@85004|Bifidobacteriales 201174|Actinobacteria C Oxidoreductase, aldo keto reductase family protein - - - - - - - - - - - - Aldo_ket_red BHPHKHDA_00167 326426.Bbr_0378 3.03e-257 704.0 COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4CZ0Y@85004|Bifidobacteriales 201174|Actinobacteria F Inosine-uridine preferring nucleoside hydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro BHPHKHDA_00168 326426.Bbr_0379 5.15e-138 390.0 COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4D0C6@85004|Bifidobacteriales 201174|Actinobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM GO:0008150,GO:0040007 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM BHPHKHDA_00169 1437609.BCAL_0857 3.56e-47 151.0 COG1837@1|root,COG1837@2|Bacteria,2IQ4C@201174|Actinobacteria,4D16Z@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the UPF0109 family - GO:0008150,GO:0040007 - ko:K06960 - - - - ko00000 - - - KH_4 BHPHKHDA_00170 326426.Bbr_0381 9.48e-85 252.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4D0PE@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 BHPHKHDA_00171 326426.Bbr_0382 2.08e-274 756.0 COG3021@1|root,COG3021@2|Bacteria,2GK2H@201174|Actinobacteria,4CYS3@85004|Bifidobacteriales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos BHPHKHDA_00172 326426.Bbr_0383 0.0 1020.0 COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,4CYY1@85004|Bifidobacteriales 201174|Actinobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB BHPHKHDA_00173 326426.Bbr_0384 2.72e-208 577.0 COG3965@1|root,COG3965@2|Bacteria,2H4CC@201174|Actinobacteria,4CZ1H@85004|Bifidobacteriales 201174|Actinobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux BHPHKHDA_00174 326426.Bbr_0385 0.0 1094.0 COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CZZ9@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e BHPHKHDA_00175 326426.Bbr_0386 9.61e-175 489.0 COG0518@1|root,COG0518@2|Bacteria,2GNA6@201174|Actinobacteria,4CYR4@85004|Bifidobacteriales 201174|Actinobacteria F Peptidase C26 - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,Methyltransf_11 BHPHKHDA_00176 326426.Bbr_0387 0.0 1417.0 COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4CZCU@85004|Bifidobacteriales 201174|Actinobacteria S ABC transporter yjjK - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn BHPHKHDA_00177 326426.Bbr_0388 8.06e-96 279.0 COG1487@1|root,COG1487@2|Bacteria,2IS29@201174|Actinobacteria,4D1D3@85004|Bifidobacteriales 201174|Actinobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase vapC - - ko:K07062 - - - - ko00000,ko01000,ko02048 - - - PIN BHPHKHDA_00178 326426.Bbr_0389 1.52e-57 178.0 COG4691@1|root,COG4691@2|Bacteria,2GRCV@201174|Actinobacteria,4D1GB@85004|Bifidobacteriales 201174|Actinobacteria S Plasmid stability protein - - - ko:K21495 - - - - ko00000,ko02048 - - - Arc BHPHKHDA_00179 326426.Bbr_0390 4.76e-119 341.0 COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CYXX@85004|Bifidobacteriales 201174|Actinobacteria E ACT domain ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0030312,GO:0032991,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C BHPHKHDA_00180 326426.Bbr_0391 0.0 1310.0 COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,4CYR0@85004|Bifidobacteriales 201174|Actinobacteria H Thiamine pyrophosphate enzyme, central domain ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N BHPHKHDA_00181 326426.Bbr_0392 7.11e-172 480.0 COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CZ98@85004|Bifidobacteriales 201174|Actinobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm BHPHKHDA_00182 326426.Bbr_0393 4.87e-37 124.0 COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4D18N@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p BHPHKHDA_00183 326426.Bbr_0394 3.89e-151 424.0 COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,4CZ0J@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized ACR, COG1399 - GO:0008150,GO:0040007 - ko:K07040 - - - - ko00000 - - - DUF177 BHPHKHDA_00184 326426.Bbr_0395 1.47e-155 440.0 2EKTZ@1|root,33EHP@2|Bacteria,2HZD3@201174|Actinobacteria,4CZV9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00185 326426.Bbr_0396 5.54e-111 319.0 COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4CYR5@85004|Bifidobacteriales 201174|Actinobacteria H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like BHPHKHDA_00186 216816.GS08_01985 4.23e-64 195.0 2CAFG@1|root,32ZDZ@2|Bacteria,2I800@201174|Actinobacteria,4D107@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3039) - - - - - - - - - - - - DUF3039 BHPHKHDA_00187 326426.Bbr_0398 9.67e-251 687.0 COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ25@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family - - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red BHPHKHDA_00188 326426.Bbr_0399 7.41e-102 294.0 COG0789@1|root,COG0789@2|Bacteria,2HZMI@201174|Actinobacteria,4D0Y1@85004|Bifidobacteriales 201174|Actinobacteria K MerR, DNA binding - - - - - - - - - - - - MerR_1 BHPHKHDA_00189 326426.Bbr_0400 5.52e-152 426.0 2DR9G@1|root,33ASJ@2|Bacteria,2I45M@201174|Actinobacteria,4D2WG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00190 326426.Bbr_0401 1.98e-314 857.0 COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CYUR@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase BHPHKHDA_00191 326426.Bbr_0402 4.49e-185 514.0 COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CZBF@85004|Bifidobacteriales 201174|Actinobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C BHPHKHDA_00192 326426.Bbr_0403 2.55e-170 477.0 COG0127@1|root,COG0127@2|Bacteria,2GM2B@201174|Actinobacteria,4CZ3F@85004|Bifidobacteriales 201174|Actinobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like BHPHKHDA_00193 326426.Bbr_0404 1.09e-225 623.0 COG0679@1|root,COG0679@2|Bacteria,2GN0R@201174|Actinobacteria,4CZ6C@85004|Bifidobacteriales 201174|Actinobacteria S Auxin Efflux Carrier - - - ko:K07088 - - - - ko00000 - - - Mem_trans BHPHKHDA_00196 326426.Bbr_0405 0.0 1139.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the GPI family pgi - 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI BHPHKHDA_00197 326426.Bbr_0406 0.0 896.0 COG1116@1|root,COG4754@1|root,COG1116@2|Bacteria,COG4754@2|Bacteria,2GN33@201174|Actinobacteria,4D00C@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - AAA_assoc_C,ABC_tran BHPHKHDA_00198 326426.Bbr_0407 0.0 1134.0 COG4986@1|root,COG4986@2|Bacteria,2GNF7@201174|Actinobacteria,4CZJS@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 BHPHKHDA_00199 326426.Bbr_0408 1.95e-78 233.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4D0V2@85004|Bifidobacteriales 201174|Actinobacteria J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 BHPHKHDA_00200 326426.Bbr_0409 4.43e-221 609.0 COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CZEY@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 BHPHKHDA_00201 326426.Bbr_0410 2.34e-205 568.0 COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CZ1U@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII BHPHKHDA_00202 326426.Bbr_0411 7.92e-270 738.0 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CYR6@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_00203 326426.Bbr_0413 0.0 1193.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CZZP@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme fadD - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding BHPHKHDA_00204 1437609.BCAL_0899 3.21e-66 215.0 COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4CZW6@85004|Bifidobacteriales 201174|Actinobacteria U Sugar (and other) transporter - - - ko:K02100 - - - - ko00000,ko02000 2.A.1.1.2 - - Sugar_tr BHPHKHDA_00205 1437609.BCAL_0899 3.51e-11 65.5 COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4CZW6@85004|Bifidobacteriales 201174|Actinobacteria U Sugar (and other) transporter - - - ko:K02100 - - - - ko00000,ko02000 2.A.1.1.2 - - Sugar_tr BHPHKHDA_00207 326426.Bbr_0415 0.0 2490.0 COG1132@1|root,COG4988@1|root,COG1132@2|Bacteria,COG4988@2|Bacteria,2GITR@201174|Actinobacteria,4CYSB@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.129,3.A.1.21 - - ABC_membrane,ABC_tran BHPHKHDA_00208 216816.GS08_02150 6.35e-51 161.0 COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,4CZW6@85004|Bifidobacteriales 201174|Actinobacteria U Sugar (and other) transporter - - - ko:K02100 - - - - ko00000,ko02000 2.A.1.1.2 - - Sugar_tr BHPHKHDA_00209 326426.Bbr_0417 0.0 907.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CZU2@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_00210 158787.BSCA_0159 1.94e-14 69.3 COG3293@1|root,COG3293@2|Bacteria,2GX1N@201174|Actinobacteria,4D2D5@85004|Bifidobacteriales 201174|Actinobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2 BHPHKHDA_00211 326426.Bbr_0348 0.0 937.0 COG1027@1|root,COG1027@2|Bacteria,2I2HG@201174|Actinobacteria,4CZ6N@85004|Bifidobacteriales 201174|Actinobacteria E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 BHPHKHDA_00212 326426.Bbr_0347 7.28e-173 484.0 COG0668@1|root,COG0668@2|Bacteria,2GZI1@201174|Actinobacteria,4CZ0A@85004|Bifidobacteriales 201174|Actinobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel,cNMP_binding BHPHKHDA_00213 326426.Bbr_0346 8.39e-236 650.0 COG1266@1|root,COG1266@2|Bacteria,2I3DW@201174|Actinobacteria,4CZJZ@85004|Bifidobacteriales 201174|Actinobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi BHPHKHDA_00214 326426.Bbr_0345 1.12e-303 829.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CZPE@85004|Bifidobacteriales 201174|Actinobacteria E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - ko:K02052 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - ABC_tran,TOBE_2 BHPHKHDA_00215 326426.Bbr_0344 3.37e-198 551.0 COG1177@1|root,COG1177@2|Bacteria,2GM0E@201174|Actinobacteria,4CZ2N@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02053 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 BHPHKHDA_00216 326426.Bbr_0343 4.85e-207 574.0 COG4132@1|root,COG4132@2|Bacteria,2GNDF@201174|Actinobacteria,4CZHE@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02054 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - BPD_transp_1 BHPHKHDA_00217 326426.Bbr_0342 3.04e-278 761.0 COG1840@1|root,COG1840@2|Bacteria,2GJFH@201174|Actinobacteria,4CZHC@85004|Bifidobacteriales 201174|Actinobacteria P Bacterial extracellular solute-binding protein - - - ko:K02055 ko02024,map02024 M00193 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11 - - SBP_bac_6 BHPHKHDA_00218 326426.Bbr_0341 7.06e-292 796.0 COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4CZ1R@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the D-alanine--D-alanine ligase family ddl GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N BHPHKHDA_00219 326426.Bbr_0340 1.38e-228 630.0 COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria,4CZHP@85004|Bifidobacteriales 201174|Actinobacteria I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus gpsA - 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N BHPHKHDA_00220 326426.Bbr_0339 1.78e-241 662.0 COG0204@1|root,COG0204@2|Bacteria,2GKVA@201174|Actinobacteria,4CZG0@85004|Bifidobacteriales 201174|Actinobacteria I Phosphate acyltransferases plsC2 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase BHPHKHDA_00221 326426.Bbr_0338 3.27e-83 246.0 COG0251@1|root,COG0251@2|Bacteria,2IFCR@201174|Actinobacteria,4D0QD@85004|Bifidobacteriales 201174|Actinobacteria J Endoribonuclease L-PSP psp1 - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP BHPHKHDA_00224 326426.Bbr_0336 3.19e-151 424.0 COG2954@1|root,COG2954@2|Bacteria,2GWD8@201174|Actinobacteria,4CZKD@85004|Bifidobacteriales 201174|Actinobacteria S CYTH - - - - - - - - - - - - - BHPHKHDA_00225 326426.Bbr_0335 5.98e-218 603.0 COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4CZHU@85004|Bifidobacteriales 201174|Actinobacteria O Tetratricopeptide repeat ybbN GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K05838 - - - - ko00000,ko03110 - - - TPR_19,TPR_20,Thioredoxin BHPHKHDA_00226 326426.Bbr_0334 3.14e-230 635.0 28PR0@1|root,2ZCCY@2|Bacteria,2GNNZ@201174|Actinobacteria,4CYX7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00227 326426.Bbr_0333 5.45e-243 673.0 2DMQ0@1|root,32SYI@2|Bacteria,2IA0N@201174|Actinobacteria,4CYQ0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00228 326426.Bbr_0332 2.43e-214 593.0 COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4CZEF@85004|Bifidobacteriales 201174|Actinobacteria M FKBP-type peptidyl-prolyl cis-trans isomerase - - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C BHPHKHDA_00229 326426.Bbr_0331 1.23e-165 464.0 COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria,4CYXA@85004|Bifidobacteriales 201174|Actinobacteria L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures nucS - - ko:K07503 - - - - ko00000,ko01000 - - - NucS BHPHKHDA_00230 326426.Bbr_0330 3.62e-65 198.0 COG0355@1|root,COG0355@2|Bacteria,2HZPJ@201174|Actinobacteria,4D16F@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC - - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N BHPHKHDA_00231 326426.Bbr_0329 0.0 970.0 COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,4CZGY@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N BHPHKHDA_00232 326426.Bbr_0328 1.2e-209 580.0 COG0224@1|root,COG0224@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CYVJ@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt BHPHKHDA_00233 326426.Bbr_0327 0.0 1058.0 COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CZI7@85004|Bifidobacteriales 201174|Actinobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N BHPHKHDA_00234 326426.Bbr_0326 4.31e-193 536.0 COG0712@1|root,COG0712@2|Bacteria,2GMJ5@201174|Actinobacteria,4CZ9V@85004|Bifidobacteriales 201174|Actinobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP BHPHKHDA_00235 216816.GS08_01445 6.77e-99 289.0 COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4CYY5@85004|Bifidobacteriales 201174|Actinobacteria C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B BHPHKHDA_00236 1437608.BBIA_0293 1.42e-39 132.0 COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4D16J@85004|Bifidobacteriales 201174|Actinobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C BHPHKHDA_00237 326426.Bbr_0323 1.33e-187 521.0 COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CYZD@85004|Bifidobacteriales 201174|Actinobacteria C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A BHPHKHDA_00238 326426.Bbr_0322 4.09e-262 717.0 COG1897@1|root,COG1897@2|Bacteria,2GK5E@201174|Actinobacteria,4CZRK@85004|Bifidobacteriales 201174|Actinobacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metAA - 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS BHPHKHDA_00240 326426.Bbr_0297 0.0 1250.0 COG5624@1|root,COG5624@2|Bacteria,2H7AK@201174|Actinobacteria,4CZMA@85004|Bifidobacteriales 201174|Actinobacteria K RNA polymerase II activating transcription factor binding - - - - - - - - - - - - - BHPHKHDA_00241 326426.Bbr_0296 0.0 1450.0 COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria,4CZSK@85004|Bifidobacteriales 201174|Actinobacteria G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 BHPHKHDA_00242 216816.GS08_01410 9.28e-118 336.0 COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4CYWS@85004|Bifidobacteriales 201174|Actinobacteria C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - iNJ661.Rv3628 Pyrophosphatase BHPHKHDA_00243 326426.Bbr_0294 1.11e-125 358.0 COG1971@1|root,COG1971@2|Bacteria,2GNBU@201174|Actinobacteria,4D01X@85004|Bifidobacteriales 201174|Actinobacteria P Probably functions as a manganese efflux pump mntP - - - - - - - - - - - Mntp BHPHKHDA_00244 326426.Bbr_0293 1.04e-153 433.0 2A0I6@1|root,30NNB@2|Bacteria,2GJ8M@201174|Actinobacteria,4D0ZN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00245 326426.Bbr_0292 2.67e-179 500.0 COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CZB9@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal glnR - - - - - - - - - - - Trans_reg_C BHPHKHDA_00246 326426.Bbr_0291 8.09e-161 450.0 COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4CZ31@85004|Bifidobacteriales 201174|Actinobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD BHPHKHDA_00247 326426.Bbr_0290 0.0 969.0 COG0747@1|root,COG0747@2|Bacteria,2GM5G@201174|Actinobacteria,4CYUZ@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 BHPHKHDA_00248 326426.Bbr_0289 0.0 1852.0 COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4CYVG@85004|Bifidobacteriales 201174|Actinobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 BHPHKHDA_00249 326426.Bbr_0288 0.0 1164.0 COG1511@1|root,COG1511@2|Bacteria,2I9PN@201174|Actinobacteria,4CZC2@85004|Bifidobacteriales 201174|Actinobacteria S domain protein - - - - - - - - - - - - - BHPHKHDA_00250 326426.Bbr_0287 1.89e-82 244.0 COG1605@1|root,COG1605@2|Bacteria,2IQ46@201174|Actinobacteria,4D12A@85004|Bifidobacteriales 201174|Actinobacteria E Chorismate mutase type II tyrA - 5.4.99.5 ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 BHPHKHDA_00251 401473.BDP_0103 4.7e-62 199.0 COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4CZJG@85004|Bifidobacteriales 201174|Actinobacteria EH Amino-transferase class IV pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 BHPHKHDA_00252 1193128.A200_08258 3.01e-46 153.0 COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_23,HTH_28 BHPHKHDA_00253 158787.BSCA_1758 2.52e-157 471.0 COG3345@1|root,COG3345@2|Bacteria 2|Bacteria G alpha-galactosidase rafA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase BHPHKHDA_00254 158787.BSCA_1757 1.09e-145 417.0 COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4CZQ9@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component araQ - - ko:K02026,ko:K10190,ko:K10242 ko02010,map02010 M00199,M00206,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.23,3.A.1.1.4 - - BPD_transp_1 BHPHKHDA_00255 158787.BSCA_1756 7.2e-159 451.0 COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria,4D0C0@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K10189,ko:K10241 ko02010,map02010 M00199,M00206 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.23,3.A.1.1.4 - - BPD_transp_1 BHPHKHDA_00256 158787.BSCA_1755 4.35e-191 545.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CZU2@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein araN - - ko:K10188 ko02010,map02010 M00199 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.4 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_00257 658088.HMPREF0987_00774 1.25e-44 160.0 COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,27K76@186928|unclassified Lachnospiraceae 186801|Clostridia K AraC-like ligand binding domain - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC BHPHKHDA_00258 566552.BIFCAT_01209 1.42e-144 423.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 BHPHKHDA_00259 1437609.BCAL_1765 5.23e-59 192.0 COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4CZJG@85004|Bifidobacteriales 201174|Actinobacteria EH Amino-transferase class IV pabC - 4.1.3.38 ko:K02619 ko00790,map00790 - R05553 RC01843,RC02148 ko00000,ko00001,ko01000 - - - Aminotran_4 BHPHKHDA_00260 326426.Bbr_0282 0.0 1114.0 COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4CZ2Z@85004|Bifidobacteriales 201174|Actinobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind BHPHKHDA_00261 326426.Bbr_0281 0.0 1111.0 COG1232@1|root,COG1232@2|Bacteria,2HZ9K@201174|Actinobacteria,4CZ3Z@85004|Bifidobacteriales 201174|Actinobacteria H Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 BHPHKHDA_00262 216816.GS08_01350 2.66e-68 206.0 2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4D0UV@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF2469 BHPHKHDA_00263 326426.Bbr_0279 9.64e-248 680.0 COG1670@1|root,COG1670@2|Bacteria,2I2GV@201174|Actinobacteria,4CYPW@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 BHPHKHDA_00264 216816.GS08_01340 0.0 974.0 COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CYUY@85004|Bifidobacteriales 201174|Actinobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey BHPHKHDA_00265 326426.Bbr_0277 0.0 994.0 COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4CZ1X@85004|Bifidobacteriales 201174|Actinobacteria F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase BHPHKHDA_00266 398513.BBNG_01427 7.57e-68 207.0 COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4D10U@85004|Bifidobacteriales 201174|Actinobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln BHPHKHDA_00267 326426.Bbr_0275 3.05e-204 568.0 COG5340@1|root,COG5340@2|Bacteria,2ICPH@201174|Actinobacteria,4CZJ7@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - BHPHKHDA_00268 326426.Bbr_0274 5.99e-226 625.0 2DRNP@1|root,33CDT@2|Bacteria,2I2HC@201174|Actinobacteria,4D2VI@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00269 326426.Bbr_0273 9.54e-214 591.0 COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D00Y@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00270 326426.Bbr_0272 2.85e-215 595.0 COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4CZE8@85004|Bifidobacteriales 201174|Actinobacteria J RNA methyltransferase TrmH family trmH - 2.1.1.34 ko:K00556 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase BHPHKHDA_00271 326426.Bbr_0271 3.99e-141 399.0 COG0461@1|root,COG0461@2|Bacteria,2HZDS@201174|Actinobacteria,4CZZ6@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE1 - - - - - - - - - - - - BHPHKHDA_00272 326426.Bbr_0270 2.18e-275 759.0 COG1322@1|root,COG1322@2|Bacteria,2GP4U@201174|Actinobacteria,4CZA5@85004|Bifidobacteriales 201174|Actinobacteria S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC BHPHKHDA_00273 326426.Bbr_0269 6.68e-57 177.0 COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4D1A2@85004|Bifidobacteriales 201174|Actinobacteria S Metal-sensitive transcriptional repressor csoR GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042221,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0046688,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal BHPHKHDA_00274 326426.Bbr_0268 0.0 1549.0 COG2217@1|root,COG4633@1|root,COG2217@2|Bacteria,COG4633@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ24@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS BHPHKHDA_00275 398513.BBNG_00191 2.45e-161 453.0 COG0580@1|root,COG0580@2|Bacteria,2GKK3@201174|Actinobacteria,4CZ7F@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP BHPHKHDA_00277 326426.Bbr_0257 1.72e-94 276.0 COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4D0P9@85004|Bifidobacteriales 201174|Actinobacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N BHPHKHDA_00278 326426.Bbr_0256 2.15e-48 154.0 COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,4D103@85004|Bifidobacteriales 201174|Actinobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 BHPHKHDA_00279 326426.Bbr_0255 4.09e-109 318.0 COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,4CZ5V@85004|Bifidobacteriales 201174|Actinobacteria L Single-stranded DNA-binding protein ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB BHPHKHDA_00280 216816.GS08_01260 2.77e-64 196.0 COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4D10X@85004|Bifidobacteriales 201174|Actinobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 BHPHKHDA_00281 216816.GS08_00260 1.18e-52 182.0 COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4CZ3V@85004|Bifidobacteriales 201174|Actinobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase BHPHKHDA_00282 326426.Bbr_0061 2.96e-47 151.0 2BFAJ@1|root,3293I@2|Bacteria,2ISGB@201174|Actinobacteria,4D185@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00283 326426.Bbr_0062 2.82e-177 493.0 COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CZJ0@85004|Bifidobacteriales 201174|Actinobacteria S Rhomboid family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,zf-B_box BHPHKHDA_00284 326426.Bbr_0063 1.98e-100 291.0 2E4NY@1|root,32ZHR@2|Bacteria,2GQPW@201174|Actinobacteria,4D0ZH@85004|Bifidobacteriales 201174|Actinobacteria D Involved in cell division crgA - - - - - - - - - - - CrgA BHPHKHDA_00285 326426.Bbr_0064 1.56e-162 457.0 COG3879@1|root,COG3879@2|Bacteria,2GJ9Y@201174|Actinobacteria,4CZ1A@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - - - - - - - - - - - - DUF881 BHPHKHDA_00286 326426.Bbr_0065 3.94e-292 797.0 COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4CYZ5@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family srtB - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase BHPHKHDA_00287 326426.Bbr_0066 9.12e-154 431.0 COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,4D09E@85004|Bifidobacteriales 201174|Actinobacteria EH para-aminobenzoate synthase glutamine amidotransferase component II trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase BHPHKHDA_00288 326426.Bbr_0067 0.0 1211.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CZFU@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase pknB GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase BHPHKHDA_00289 326426.Bbr_0068 1.54e-221 611.0 COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CYUK@85004|Bifidobacteriales 201174|Actinobacteria T Protein tyrosine kinase pknA - 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase BHPHKHDA_00290 326426.Bbr_0069 0.0 915.0 COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,4CYTI@85004|Bifidobacteriales 201174|Actinobacteria M penicillin-binding protein pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05364 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01011 - - - Transpeptidase BHPHKHDA_00291 326426.Bbr_0070 0.0 966.0 COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CZ67@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the SEDS family rodA GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE BHPHKHDA_00292 326426.Bbr_0071 0.0 1001.0 COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CZDN@85004|Bifidobacteriales 201174|Actinobacteria T Sigma factor PP2C-like phosphatases pstP GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 BHPHKHDA_00293 326426.Bbr_0072 8.95e-105 304.0 COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D0RN@85004|Bifidobacteriales 201174|Actinobacteria T Inner membrane component of T3SS, cytoplasmic domain fhaB GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - - - - - - - - - - FHA,Yop-YscD_cpl BHPHKHDA_00294 326426.Bbr_0073 8.7e-166 463.0 COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4CYUI@85004|Bifidobacteriales 201174|Actinobacteria T Protein of unknown function (DUF2662) fhaA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - - - - - - - - - - DUF3662,FHA,Yop-YscD_cpl BHPHKHDA_00295 326426.Bbr_0074 0.0 1894.0 COG1506@1|root,COG1506@2|Bacteria,2GJ6A@201174|Actinobacteria,4CZAE@85004|Bifidobacteriales 201174|Actinobacteria E Dipeptidyl peptidase IV (DPP IV) N-terminal region pepX - 3.4.14.5 ko:K01278 ko04974,map04974 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - DPPIV_N,PD40,Peptidase_S9 BHPHKHDA_00296 326426.Bbr_0075 1.08e-270 739.0 COG2267@1|root,COG2267@2|Bacteria,2HZ9U@201174|Actinobacteria,4CZ5E@85004|Bifidobacteriales 201174|Actinobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 BHPHKHDA_00297 326426.Bbr_0076 2.45e-119 340.0 COG0071@1|root,COG0071@2|Bacteria,2HZHR@201174|Actinobacteria,4D0H9@85004|Bifidobacteriales 201174|Actinobacteria O Hsp20/alpha crystallin family - - - - - - - - - - - - HSP20 BHPHKHDA_00298 326426.Bbr_0077 3.74e-218 603.0 COG0697@1|root,COG0697@2|Bacteria,2GM6M@201174|Actinobacteria,4CZPP@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA BHPHKHDA_00299 216816.GS08_00370 7.42e-28 101.0 29P0D@1|root,309YI@2|Bacteria,2GV4X@201174|Actinobacteria,4D1M7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00300 326426.Bbr_0079 0.0 878.0 COG0627@1|root,COG0627@2|Bacteria,2GP6Q@201174|Actinobacteria,4CYXF@85004|Bifidobacteriales 201174|Actinobacteria S Putative esterase - - - - - - - - - - - - Esterase BHPHKHDA_00301 326426.Bbr_0080 0.0 1711.0 COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria,4CYW5@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised conserved protein (DUF2156) lysX - - - - - - - - - - - DUF2156,Rhomboid BHPHKHDA_00302 326426.Bbr_0081 5.21e-256 700.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2GJ1S@201174|Actinobacteria,4CZXJ@85004|Bifidobacteriales 201174|Actinobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR BHPHKHDA_00303 326426.Bbr_0082 1.01e-168 471.0 COG3467@1|root,COG3467@2|Bacteria,2IGUA@201174|Actinobacteria,4D0SF@85004|Bifidobacteriales 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 BHPHKHDA_00304 326426.Bbr_0083 5.4e-252 691.0 COG3177@1|root,COG3177@2|Bacteria,2IAAQ@201174|Actinobacteria,4CZAM@85004|Bifidobacteriales 201174|Actinobacteria S Fic/DOC family - - - - - - - - - - - - Fic BHPHKHDA_00305 326426.Bbr_0084 2.82e-210 586.0 COG1215@1|root,COG1215@2|Bacteria,2I2IF@201174|Actinobacteria,4CYW6@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 BHPHKHDA_00306 1680.BADO_0964 8.56e-217 615.0 COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria,4D0YP@85004|Bifidobacteriales 201174|Actinobacteria H C-5 cytosine-specific DNA methylase - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase,EndIII_4Fe-2S BHPHKHDA_00307 1435051.BMOU_0530 1.62e-295 840.0 arCOG06613@1|root,2Z7VT@2|Bacteria,2I8ZN@201174|Actinobacteria,4CZPC@85004|Bifidobacteriales 201174|Actinobacteria S AIPR protein - - - - - - - - - - - - AIPR BHPHKHDA_00309 1435051.BMOU_0529 6.73e-40 144.0 2AVMY@1|root,31YDE@2|Bacteria,2HZVI@201174|Actinobacteria,4D1XI@85004|Bifidobacteriales 201174|Actinobacteria S Putative PD-(D/E)XK family member, (DUF4420) - - - - - - - - - - - - DUF4420 BHPHKHDA_00310 1680.BADO_0961 8.49e-313 892.0 COG1100@1|root,COG1100@2|Bacteria,2I8GF@201174|Actinobacteria,4D1JE@85004|Bifidobacteriales 201174|Actinobacteria L Z1 domain - - - - - - - - - - - - Z1 BHPHKHDA_00311 1680.BADO_0960 1.24e-215 610.0 COG0323@1|root,COG0323@2|Bacteria,2IB2D@201174|Actinobacteria,4D234@85004|Bifidobacteriales 201174|Actinobacteria L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c_3 BHPHKHDA_00312 566552.BIFCAT_01947 1.91e-159 453.0 2DKUR@1|root,30DNK@2|Bacteria,2IEVI@201174|Actinobacteria,4CYWA@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4928) - - - - - - - - - - - - DUF4928 BHPHKHDA_00313 326426.Bbr_0216 1.1e-208 585.0 COG0270@1|root,COG0270@2|Bacteria,2HZJB@201174|Actinobacteria,4D0NW@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase BHPHKHDA_00314 216816.GS08_00410 1.23e-69 210.0 COG0393@1|root,COG0393@2|Bacteria,2IQNY@201174|Actinobacteria,4D0ZM@85004|Bifidobacteriales 201174|Actinobacteria S Putative heavy-metal-binding - - - - - - - - - - - - YbjQ_1 BHPHKHDA_00315 216816.GS08_00415 1.65e-115 331.0 COG2153@1|root,COG2153@2|Bacteria,2HZKP@201174|Actinobacteria,4D0UN@85004|Bifidobacteriales 201174|Actinobacteria Q Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 BHPHKHDA_00316 326426.Bbr_0087 6.07e-192 534.0 COG1272@1|root,COG1272@2|Bacteria,2HRAC@201174|Actinobacteria,4D0D6@85004|Bifidobacteriales 201174|Actinobacteria S Haemolysin-III related - - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII BHPHKHDA_00318 326426.Bbr_0088 0.0 895.0 COG0343@1|root,COG0343@2|Bacteria,2GMWY@201174|Actinobacteria,4CZNX@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT BHPHKHDA_00319 326426.Bbr_0089 0.0 956.0 COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CZAP@85004|Bifidobacteriales 201174|Actinobacteria O Domain present in PSD-95, Dlg, and ZO-1/2. degP - - ko:K08372 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Trypsin_2 BHPHKHDA_00320 326426.Bbr_0090 0.0 1479.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4CZ4F@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hemerythrin,Hydrolase BHPHKHDA_00321 326426.Bbr_0091 0.0 953.0 COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,4CZIT@85004|Bifidobacteriales 201174|Actinobacteria C Pyridine nucleotide-disulphide oxidoreductase fprA - 1.18.1.2,1.19.1.1 ko:K00528 - - R10159 - ko00000,ko01000 - - - Pyr_redox_2 BHPHKHDA_00322 216816.GS08_00460 9.22e-217 599.0 COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CYVY@85004|Bifidobacteriales 201174|Actinobacteria O Belongs to the peptidase M48B family htpX GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 BHPHKHDA_00324 326426.Bbr_0093 2.17e-214 593.0 COG0697@1|root,COG0697@2|Bacteria,2HZCH@201174|Actinobacteria,4CZRZ@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA BHPHKHDA_00325 326426.Bbr_0094 1e-248 683.0 COG0191@1|root,COG0191@2|Bacteria,2GM5P@201174|Actinobacteria,4CZJI@85004|Bifidobacteriales 201174|Actinobacteria G Fructose-bisphosphate aldolase class-II fbaA - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase BHPHKHDA_00326 326426.Bbr_0095 2.27e-307 838.0 COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,4CZ0U@85004|Bifidobacteriales 201174|Actinobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt BHPHKHDA_00327 326426.Bbr_0096 0.0 970.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,2GPPN@201174|Actinobacteria,4CZQR@85004|Bifidobacteriales 201174|Actinobacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC BHPHKHDA_00328 326426.Bbr_0097 1.24e-200 561.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D0RK@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB BHPHKHDA_00329 216816.GS08_00515 5.18e-81 241.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB BHPHKHDA_00330 216816.GS08_00540 1.02e-63 206.0 COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZSH@85004|Bifidobacteriales 201174|Actinobacteria E Receptor family ligand binding region livK - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 BHPHKHDA_00331 326426.Bbr_0099 1.15e-257 706.0 COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 BHPHKHDA_00332 216816.GS08_00550 0.0 1019.0 COG0366@1|root,COG0366@2|Bacteria,2GNEC@201174|Actinobacteria,4CZ4T@85004|Bifidobacteriales 201174|Actinobacteria G Domain of unknown function (DUF1964) gtfA - 2.4.1.7 ko:K00690 ko00500,map00500 - R00803 RC00028 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1964 BHPHKHDA_00333 326426.Bbr_0101 0.0 995.0 COG2211@1|root,COG2211@2|Bacteria,2GJZG@201174|Actinobacteria,4CZ93@85004|Bifidobacteriales 201174|Actinobacteria G Transporter major facilitator family protein scrT - - - - - - - - - - - MFS_1,MFS_2 BHPHKHDA_00334 326426.Bbr_0102 5.98e-243 668.0 COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 BHPHKHDA_00335 326426.Bbr_0103 0.0 876.0 COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales 201174|Actinobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr BHPHKHDA_00336 326426.Bbr_0104 7.18e-260 711.0 COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN BHPHKHDA_00337 326426.Bbr_0110 1.76e-260 712.0 COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN BHPHKHDA_00338 326426.Bbr_1240 0.0 1005.0 COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CZAF@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M BHPHKHDA_00339 326426.Bbr_1241 3.91e-245 672.0 COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CZT9@85004|Bifidobacteriales 201174|Actinobacteria V Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6,FemAB BHPHKHDA_00340 326426.Bbr_1242 2.6e-58 184.0 COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria,4CZT9@85004|Bifidobacteriales 201174|Actinobacteria V Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6,FemAB BHPHKHDA_00341 326426.Bbr_1243 0.0 2166.0 COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CZ8Q@85004|Bifidobacteriales 201174|Actinobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge BHPHKHDA_00342 326426.Bbr_1244 0.0 1040.0 COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CZG9@85004|Bifidobacteriales 201174|Actinobacteria H Mur ligase middle domain folC GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2447c Mur_ligase_C,Mur_ligase_M BHPHKHDA_00343 326426.Bbr_1245 0.0 1075.0 COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CZIA@85004|Bifidobacteriales 201174|Actinobacteria E Aminopeptidase P, N-terminal domain pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - AMP_N,Peptidase_M24 BHPHKHDA_00344 326426.Bbr_1246 5.09e-124 353.0 COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4CZS4@85004|Bifidobacteriales 201174|Actinobacteria F NUDIX domain - - - - - - - - - - - - NUDIX BHPHKHDA_00345 326426.Bbr_1247 5.61e-311 847.0 COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CZKB@85004|Bifidobacteriales 201174|Actinobacteria G Amidohydrolase family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 BHPHKHDA_00346 326426.Bbr_1248 5.46e-192 533.0 COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4CYYE@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso BHPHKHDA_00347 326426.Bbr_1249 1.07e-264 725.0 COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4CZUF@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - Crp,ROK BHPHKHDA_00348 326426.Bbr_1250 2e-211 585.0 COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4CZII@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK BHPHKHDA_00350 326426.Bbr_1251 6.67e-281 769.0 COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4CYV9@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HTH_24,MarR_2,ROK BHPHKHDA_00351 326426.Bbr_1252 5.56e-215 593.0 COG0524@1|root,COG0524@2|Bacteria,2HZB3@201174|Actinobacteria,4CZFC@85004|Bifidobacteriales 201174|Actinobacteria G pfkB family carbohydrate kinase - - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB BHPHKHDA_00352 398513.BBNG_00476 8.35e-07 52.4 2B3SJ@1|root,31WG6@2|Bacteria,2GX7W@201174|Actinobacteria,4D1T0@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00354 326426.Bbr_1255 3.94e-229 633.0 COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4D04A@85004|Bifidobacteriales 201174|Actinobacteria D Cell division protein FtsQ ftsQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 BHPHKHDA_00355 326426.Bbr_1256 0.0 980.0 COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CZ3B@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M BHPHKHDA_00356 326426.Bbr_1257 1.38e-275 754.0 COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4CYQS@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227,6.3.2.8 ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 - R03193,R05032,R05662 RC00005,RC00049,RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 BHPHKHDA_00357 326426.Bbr_1258 2.45e-288 788.0 COG0772@1|root,COG0772@2|Bacteria,2GKXP@201174|Actinobacteria,4CYPZ@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the SEDS family ftsW GO:0008150,GO:0040007 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 - FTSW_RODA_SPOVE BHPHKHDA_00358 326426.Bbr_1259 0.0 931.0 COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4CZKI@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - iNJ661.Rv2155c AlaDh_PNT_C,Mur_ligase_C,Mur_ligase_M BHPHKHDA_00359 326426.Bbr_1260 1.58e-263 722.0 COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,4CYRX@85004|Bifidobacteriales 201174|Actinobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 BHPHKHDA_00360 326426.Bbr_1261 0.0 871.0 COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4CZ7U@85004|Bifidobacteriales 201174|Actinobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M BHPHKHDA_00361 326426.Bbr_1262 3.7e-200 555.0 COG0769@1|root,COG0769@2|Bacteria,2GMZF@201174|Actinobacteria,4CYWT@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan - - - - - - - - - - - - - BHPHKHDA_00362 326426.Bbr_1263 0.0 1149.0 COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,4CYS8@85004|Bifidobacteriales 201174|Actinobacteria M Penicillin-binding protein, transpeptidase domain protein ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase BHPHKHDA_00363 326426.Bbr_1264 1.84e-90 266.0 COG2919@1|root,COG2919@2|Bacteria,2IKUA@201174|Actinobacteria,4D109@85004|Bifidobacteriales 201174|Actinobacteria D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - - - - - - - - - - - BHPHKHDA_00364 326426.Bbr_1265 2.09e-243 669.0 COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CYRM@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 BHPHKHDA_00365 326426.Bbr_1266 2.33e-120 343.0 COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4D0P1@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ BHPHKHDA_00366 326426.Bbr_1267 0.0 1468.0 COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4CYUF@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2,Viral_helicase1 BHPHKHDA_00367 326426.Bbr_1268 4.79e-292 796.0 COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CYPT@85004|Bifidobacteriales 201174|Actinobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C BHPHKHDA_00368 326426.Bbr_1269 4.08e-101 293.0 COG1327@1|root,COG1327@2|Bacteria,2IHU9@201174|Actinobacteria,4D0P7@85004|Bifidobacteriales 201174|Actinobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone BHPHKHDA_00369 326426.Bbr_1270 1.43e-67 206.0 COG1388@1|root,COG1388@2|Bacteria,2HVH4@201174|Actinobacteria,4D1G8@85004|Bifidobacteriales 201174|Actinobacteria M Lysin motif - - - - - - - - - - - - LysM BHPHKHDA_00370 326426.Bbr_1271 4.82e-165 462.0 COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CZ26@85004|Bifidobacteriales 201174|Actinobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 BHPHKHDA_00371 326426.Bbr_1272 1.39e-207 576.0 COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,4CZAB@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux,ZT_dimer BHPHKHDA_00372 326426.Bbr_1273 2.67e-224 619.0 COG0039@1|root,COG0039@2|Bacteria,2GN5S@201174|Actinobacteria,4CYWK@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27,1.1.1.37 ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R00703,R01000,R03104,R07136 RC00031,RC00044 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N BHPHKHDA_00373 326426.Bbr_1274 0.0 945.0 COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CZCB@85004|Bifidobacteriales 201174|Actinobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 BHPHKHDA_00374 326426.Bbr_1275 1.99e-159 446.0 COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4CZP1@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L11 methyltransferase (PrmA) rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS BHPHKHDA_00375 326426.Bbr_1276 0.0 2689.0 COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4CZ3C@85004|Bifidobacteriales 201174|Actinobacteria L Helicase associated domain (HA2) Add an annotation hrpA - 3.6.4.13 ko:K03578 - - - - ko00000,ko01000 - - - AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind BHPHKHDA_00376 326426.Bbr_1277 1.24e-279 765.0 COG0477@1|root,COG2814@2|Bacteria,2GK8C@201174|Actinobacteria,4CZH1@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K18567,ko:K19577 - - - - ko00000,ko02000 2.A.1.2.25,2.A.1.2.65 - - MFS_1,Sugar_tr BHPHKHDA_00377 326426.Bbr_1278 0.0 918.0 COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CZ0G@85004|Bifidobacteriales 201174|Actinobacteria E glutamine synthetase glnA2 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N BHPHKHDA_00378 326426.Bbr_1279 0.0 965.0 COG4320@1|root,COG4320@2|Bacteria,2GKEK@201174|Actinobacteria,4CZIY@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized protein conserved in bacteria (DUF2252) - - - - - - - - - - - - DUF2252 BHPHKHDA_00379 326426.Bbr_1280 5.86e-168 469.0 COG0106@1|root,COG0106@2|Bacteria,2GJ4V@201174|Actinobacteria,4CZEA@85004|Bifidobacteriales 201174|Actinobacteria E Histidine biosynthesis protein hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16,5.3.1.24 ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 M00023,M00026 R03509,R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth BHPHKHDA_00380 326426.Bbr_1281 3.43e-154 432.0 COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,4CZGA@85004|Bifidobacteriales 201174|Actinobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase BHPHKHDA_00381 326426.Bbr_1282 7.57e-163 457.0 2EKCN@1|root,33E2Y@2|Bacteria,2GNIC@201174|Actinobacteria,4D0B5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00382 326426.Bbr_1283 1.66e-144 407.0 COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,4CZDD@85004|Bifidobacteriales 201174|Actinobacteria E Imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013,R03457 RC00017,RC00932 ko00000,ko00001,ko00002,ko01000 - - - IGPD BHPHKHDA_00383 326426.Bbr_1284 1.57e-279 764.0 COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CZDT@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 BHPHKHDA_00384 326426.Bbr_1285 0.0 879.0 COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,4CZ3E@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1599 Histidinol_dh BHPHKHDA_00385 326426.Bbr_1286 4.18e-71 214.0 COG1254@1|root,COG1254@2|Bacteria,2HZRI@201174|Actinobacteria,4D1EM@85004|Bifidobacteriales 201174|Actinobacteria C Acylphosphatase acyP - 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase BHPHKHDA_00386 326426.Bbr_1287 7.81e-199 550.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CZ1F@85004|Bifidobacteriales 201174|Actinobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red BHPHKHDA_00387 547043.BIFPSEUDO_03219 0.0 1581.0 COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria,4CZZK@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 65, N-terminal domain - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Big_2,Big_3,Glyco_hyd_65N_2 BHPHKHDA_00388 326426.Bbr_1289 7.85e-210 580.0 COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales 201174|Actinobacteria EM Dihydrodipicolinate synthetase family - - 4.1.2.28 ko:K22397 ko00040,map00040 - R01782 RC00307,RC00572 ko00000,ko00001,ko01000 - - - DHDPS BHPHKHDA_00390 547043.BIFPSEUDO_03222 1.39e-186 518.0 COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CZXI@85004|Bifidobacteriales 201174|Actinobacteria IQ KR domain - - 1.1.1.100,1.1.1.413 ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R08926,R10116,R10120,R11671 RC00029,RC00066,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 BHPHKHDA_00391 547043.BIFPSEUDO_03223 1.18e-312 851.0 COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4D0EI@85004|Bifidobacteriales 201174|Actinobacteria M Enolase C-terminal domain-like - - 4.2.1.68 ko:K18334 ko00051,ko01120,map00051,map01120 - R03688 RC00543 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N BHPHKHDA_00392 547043.BIFPSEUDO_03224 0.0 921.0 COG1653@1|root,COG1653@2|Bacteria,2I5GP@201174|Actinobacteria,4D2XQ@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 BHPHKHDA_00393 547043.BIFPSEUDO_03225 5.59e-224 618.0 COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CZTQ@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00394 547043.BIFPSEUDO_03226 2.27e-202 561.0 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZW4@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00395 547043.BIFPSEUDO_03227 8.17e-109 322.0 COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZI0@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, lacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BHPHKHDA_00398 547043.BIFPSEUDO_04260 4.92e-18 75.1 2B4NV@1|root,325VP@2|Bacteria,2HB5J@201174|Actinobacteria,4D2KK@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Extracellular, score 8.82 - - - - - - - - - - - - - BHPHKHDA_00399 1437608.BBIA_0616 1.59e-103 314.0 COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives IS30 family - - - - - - - - - - - - HTH_38,rve BHPHKHDA_00402 547043.BIFPSEUDO_04438 3.83e-17 73.2 29G83@1|root,3035W@2|Bacteria,2GQWW@201174|Actinobacteria,4D1G9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00403 216816.GS08_04235 5.77e-152 428.0 COG1309@1|root,COG1309@2|Bacteria,2HZJX@201174|Actinobacteria,4D0QJ@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N BHPHKHDA_00404 326426.Bbr_0832 3.63e-274 753.0 COG2271@1|root,COG2271@2|Bacteria,2HZ9S@201174|Actinobacteria,4CZ4Z@85004|Bifidobacteriales 201174|Actinobacteria G Transmembrane secretion effector - - - - - - - - - - - - MFS_1 BHPHKHDA_00405 326426.Bbr_0831 1.76e-23 91.3 COG3093@1|root,COG3093@2|Bacteria 2|Bacteria K addiction module antidote protein HigA - - - ko:K21498 - - - - ko00000,ko02048 - - - HTH_3 BHPHKHDA_00406 216816.GS08_04225 1.04e-307 838.0 COG3550@1|root,COG3550@2|Bacteria,2IEMD@201174|Actinobacteria,4CZ2C@85004|Bifidobacteriales 201174|Actinobacteria S HipA-like C-terminal domain - - - - - - - - - - - - HipA_C BHPHKHDA_00407 216816.GS08_04190 1.52e-255 704.0 COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,4CZBU@85004|Bifidobacteriales 201174|Actinobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C BHPHKHDA_00408 326426.Bbr_0817 9.65e-143 404.0 COG0765@1|root,COG0765@2|Bacteria,2GM0I@201174|Actinobacteria,4CZ8E@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component glnP2 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BHPHKHDA_00409 326426.Bbr_0816 2.26e-153 432.0 COG0765@1|root,COG0765@2|Bacteria,2GN44@201174|Actinobacteria,4CZG7@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component glnP - - ko:K02029,ko:K10040 ko02010,map02010 M00228,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BHPHKHDA_00410 326426.Bbr_0815 7.78e-177 493.0 COG1126@1|root,COG1126@2|Bacteria,2H1ZM@201174|Actinobacteria,4CZTK@85004|Bifidobacteriales 201174|Actinobacteria E ATP binding protein of ABC transporter for glutamate aspartate K02028 glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran BHPHKHDA_00411 326426.Bbr_0814 4e-198 549.0 COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZAC@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins glnH - - ko:K02030,ko:K10039 ko02010,map02010 M00228,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BHPHKHDA_00412 326426.Bbr_0813 2.3e-190 529.0 COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4CZIV@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer BHPHKHDA_00413 326426.Bbr_0812 0.0 989.0 COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria,4CZ9T@85004|Bifidobacteriales 201174|Actinobacteria S alpha/beta hydrolase fold pip - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 BHPHKHDA_00414 326426.Bbr_0811 0.0 1489.0 COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4CZ1M@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 BHPHKHDA_00415 326426.Bbr_0810 1.18e-179 501.0 COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CYQW@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg BHPHKHDA_00416 326426.Bbr_0809 0.0 1627.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CZUR@85004|Bifidobacteriales 201174|Actinobacteria MV MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BHPHKHDA_00417 326426.Bbr_0808 2.44e-214 592.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00418 326426.Bbr_0807 0.0 868.0 COG2873@1|root,COG2873@2|Bacteria,2I2EB@201174|Actinobacteria,4CZCT@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-V - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP BHPHKHDA_00419 326426.Bbr_0806 2.26e-210 581.0 COG2240@1|root,COG2240@2|Bacteria,2HS59@201174|Actinobacteria,4CYQC@85004|Bifidobacteriales 201174|Actinobacteria H Phosphomethylpyrimidine kinase pdxY - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin BHPHKHDA_00420 1437610.BREU_2146 4.32e-29 114.0 COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives IS30 family - - - - - - - - - - - - HTH_38,rve BHPHKHDA_00421 326426.Bbr_0805 2.51e-98 285.0 COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4D191@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the UPF0102 family yraN - - ko:K07460 - - - - ko00000 - - - UPF0102 BHPHKHDA_00422 326426.Bbr_0804 0.0 1001.0 COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria,4CYUB@85004|Bifidobacteriales 201174|Actinobacteria O Magnesium chelatase, subunit ChlI C-terminal comM GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C BHPHKHDA_00423 326426.Bbr_0803 0.0 1068.0 COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria,4CYVW@85004|Bifidobacteriales 201174|Actinobacteria LU DNA recombination-mediator protein A dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A BHPHKHDA_00424 326426.Bbr_0802 0.0 1204.0 COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4CYT5@85004|Bifidobacteriales 201174|Actinobacteria C Succinate dehydrogenase flavoprotein subunit sdhA GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00115,M00149,M00173,M00374,M00376 R00357,R00481,R02164 RC00006,RC00045,RC02566 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C BHPHKHDA_00425 326426.Bbr_0801 4e-233 640.0 COG0479@1|root,COG0479@2|Bacteria,2GP9C@201174|Actinobacteria,4CZWJ@85004|Bifidobacteriales 201174|Actinobacteria C 4Fe-4S dicluster domain sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_8 BHPHKHDA_00426 326426.Bbr_0800 1.88e-145 411.0 COG4122@1|root,COG4122@2|Bacteria,2HXV7@201174|Actinobacteria,4CZZN@85004|Bifidobacteriales 201174|Actinobacteria S O-methyltransferase safC - - - - - - - - - - - Methyltransf_3 BHPHKHDA_00427 326426.Bbr_0799 2.65e-214 592.0 COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4CZ8R@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the LOG family fmt2 - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox BHPHKHDA_00428 326426.Bbr_0798 5.35e-305 835.0 COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria,4CZES@85004|Bifidobacteriales 201174|Actinobacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 BHPHKHDA_00429 326426.Bbr_0797 2.41e-302 823.0 COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4CZFH@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 BHPHKHDA_00432 326426.Bbr_0796 9.18e-317 864.0 COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4CYT6@85004|Bifidobacteriales 201174|Actinobacteria O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX BHPHKHDA_00433 326426.Bbr_0795 1.28e-155 437.0 COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CZVF@85004|Bifidobacteriales 201174|Actinobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease BHPHKHDA_00434 326426.Bbr_0794 2.96e-151 424.0 COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,4CYUU@85004|Bifidobacteriales 201174|Actinobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP1 - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease BHPHKHDA_00435 326426.Bbr_0793 1.85e-78 234.0 2A3Y6@1|root,30SGI@2|Bacteria,2IM76@201174|Actinobacteria,4D10Z@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00436 326426.Bbr_0792 1.76e-312 854.0 COG0038@1|root,COG0038@2|Bacteria,2GPPN@201174|Actinobacteria,4CZPX@85004|Bifidobacteriales 201174|Actinobacteria P Voltage gated chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC BHPHKHDA_00437 326426.Bbr_0791 3.47e-303 830.0 COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CZ6P@85004|Bifidobacteriales 201174|Actinobacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N BHPHKHDA_00438 326426.Bbr_0790 0.0 870.0 COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CYUV@85004|Bifidobacteriales 201174|Actinobacteria J 3'-5' exonuclease rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC BHPHKHDA_00439 326426.Bbr_0789 7.83e-153 429.0 2B58P@1|root,31Y2Q@2|Bacteria,2HZMM@201174|Actinobacteria,4D0Y9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3000) - - - - - - - - - - - - DUF3000 BHPHKHDA_00440 326426.Bbr_0788 5.19e-222 610.0 COG1180@1|root,COG1180@2|Bacteria,2GN2B@201174|Actinobacteria,4CZ5Y@85004|Bifidobacteriales 201174|Actinobacteria C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM BHPHKHDA_00441 326426.Bbr_0787 0.0 1613.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 201174|Actinobacteria C Pyruvate formate lyase-like pflB - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like BHPHKHDA_00442 326426.Bbr_0786 1.24e-51 162.0 2EHMB@1|root,33BD3@2|Bacteria,2HZRX@201174|Actinobacteria,4D1G1@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00443 326426.Bbr_0785 0.0 1118.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CZ14@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE - 6.3.5.1 ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase BHPHKHDA_00444 326426.Bbr_0784 5.66e-285 778.0 COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4CZC6@85004|Bifidobacteriales 201174|Actinobacteria S Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 BHPHKHDA_00445 326426.Bbr_0783 3.9e-146 413.0 COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CZWG@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 BHPHKHDA_00446 326426.Bbr_0782 6.93e-281 768.0 COG1135@1|root,COG1135@2|Bacteria,2GJ9P@201174|Actinobacteria,4CZYI@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL BHPHKHDA_00447 326426.Bbr_0781 4.26e-224 619.0 COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CZNB@85004|Bifidobacteriales 201174|Actinobacteria P NLPA lipoprotein - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 BHPHKHDA_00448 326426.Bbr_0780 1.15e-200 555.0 COG0561@1|root,COG0561@2|Bacteria,2HZBH@201174|Actinobacteria,4CZIQ@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 BHPHKHDA_00451 326426.Bbr_0779 7.2e-174 484.0 COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CYXK@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 BHPHKHDA_00452 326426.Bbr_0778 5.45e-86 253.0 COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4D11U@85004|Bifidobacteriales 201174|Actinobacteria J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS BHPHKHDA_00453 326426.Bbr_0777 0.0 910.0 COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4CZ4C@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3,NTP_transferase BHPHKHDA_00454 326426.Bbr_0776 0.0 1697.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 201174|Actinobacteria G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N BHPHKHDA_00455 326426.Bbr_0775 0.0 1032.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CZC3@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase BHPHKHDA_00456 1034345.CAEM01000015_gene279 3.48e-23 90.9 2A3S7@1|root,30SA2@2|Bacteria,2HD8K@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00457 1034345.CAEM01000015_gene274 5.21e-09 53.5 2C6FK@1|root,300XE@2|Bacteria,2H8H8@201174|Actinobacteria,4CYDF@84998|Coriobacteriia 1034345.CAEM01000015_gene274|- - - - - - - - - - - - - - - - BHPHKHDA_00458 1034345.CAEM01000015_gene278 3.59e-38 128.0 2C6FK@1|root,300XE@2|Bacteria,2H8H8@201174|Actinobacteria,4CYDF@84998|Coriobacteriia 1034345.CAEM01000015_gene278|- - - - - - - - - - - - - - - - BHPHKHDA_00459 710685.MycrhN_2870 4.79e-69 237.0 2AU07@1|root,31JK1@2|Bacteria,2IJI9@201174|Actinobacteria 201174|Actinobacteria S Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 BHPHKHDA_00460 1256908.HMPREF0373_00083 3.2e-138 391.0 COG3340@1|root,COG3340@2|Bacteria,1V244@1239|Firmicutes,24A93@186801|Clostridia,25Y5D@186806|Eubacteriaceae 186801|Clostridia E Belongs to the peptidase S51 family - - 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 BHPHKHDA_00462 326426.Bbr_1293 0.0 1305.0 COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales 201174|Actinobacteria S MCRA family - - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA BHPHKHDA_00463 326426.Bbr_1294 1.08e-214 592.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CZXR@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family dkgV - - - - - - - - - - - Aldo_ket_red BHPHKHDA_00465 326426.Bbr_1296 0.0 2365.0 COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4CZKT@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III alpha subunit dnaE GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon BHPHKHDA_00466 326426.Bbr_1297 1.01e-254 698.0 COG2378@1|root,COG2378@2|Bacteria,2IAIA@201174|Actinobacteria,4CYRS@85004|Bifidobacteriales 201174|Actinobacteria K WYL domain - - - - - - - - - - - - HTH_11,WYL BHPHKHDA_00467 326426.Bbr_1298 4.29e-227 625.0 COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CYYR@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 BHPHKHDA_00468 326426.Bbr_1299 2.45e-116 334.0 COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4D0WR@85004|Bifidobacteriales 201174|Actinobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 BHPHKHDA_00469 1437610.BREU_1869 2.85e-105 326.0 COG1566@1|root,COG1566@2|Bacteria,2I2G9@201174|Actinobacteria,4CZ5W@85004|Bifidobacteriales 201174|Actinobacteria V DivIVA protein - - - - - - - - - - - - DivIVA BHPHKHDA_00470 326426.Bbr_1301 3.44e-60 186.0 COG0762@1|root,COG0762@2|Bacteria,2GQI1@201174|Actinobacteria,4D17B@85004|Bifidobacteriales 201174|Actinobacteria S YGGT family - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT BHPHKHDA_00471 326426.Bbr_1302 1.42e-91 270.0 COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,4D0RJ@85004|Bifidobacteriales 201174|Actinobacteria D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K09772 - - - - ko00000,ko03036 - - - SepF BHPHKHDA_00472 326426.Bbr_1303 8.65e-275 753.0 COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CZ10@85004|Bifidobacteriales 201174|Actinobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin BHPHKHDA_00473 326426.Bbr_1304 2.02e-316 859.0 COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4CZFD@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - - - - - - - - - - Dus BHPHKHDA_00474 326426.Bbr_1305 0.0 1023.0 COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,4CYZU@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b BHPHKHDA_00475 216816.GS08_07010 1.05e-202 563.0 COG2145@1|root,COG2145@2|Bacteria,2IC73@201174|Actinobacteria,4CZU8@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK BHPHKHDA_00476 326426.Bbr_1312 0.0 1789.0 COG0352@1|root,COG0422@1|root,COG0352@2|Bacteria,COG0422@2|Bacteria,2GJ3Y@201174|Actinobacteria,4D2W5@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM BHPHKHDA_00477 216816.GS08_07020 4.39e-287 784.0 COG1222@1|root,COG1222@2|Bacteria,2I5C1@201174|Actinobacteria,4D0DP@85004|Bifidobacteriales 201174|Actinobacteria O AAA domain (Cdc48 subfamily) - - - ko:K13525 ko04141,ko05134,map04141,map05134 M00400,M00403 - - ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 3.A.16.1 - - AAA BHPHKHDA_00478 216816.GS08_07025 6.57e-182 507.0 COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4CYQA@85004|Bifidobacteriales 201174|Actinobacteria H Phosphomethylpyrimidine kinase thiD GO:0008150,GO:0040007 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin BHPHKHDA_00479 216816.GS08_07030 9.51e-81 239.0 COG0011@1|root,COG0011@2|Bacteria,2IQ7E@201174|Actinobacteria,4D14E@85004|Bifidobacteriales 201174|Actinobacteria S Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Thiamine_BP BHPHKHDA_00480 216816.GS08_07035 0.0 868.0 COG2271@1|root,COG2271@2|Bacteria,2I32P@201174|Actinobacteria,4D2WZ@85004|Bifidobacteriales 201174|Actinobacteria G Sugar (and other) transporter - - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,MFS_4,Sugar_tr BHPHKHDA_00481 326426.Bbr_1317 6.5e-294 807.0 COG4585@1|root,COG4585@2|Bacteria,2I370@201174|Actinobacteria,4D0JE@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - - BHPHKHDA_00482 326426.Bbr_1318 5.01e-159 446.0 COG2197@1|root,COG2197@2|Bacteria,2HRPE@201174|Actinobacteria,4D098@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg BHPHKHDA_00483 326426.Bbr_1319 8.19e-244 669.0 2CK5B@1|root,2ZYDK@2|Bacteria,2HU05@201174|Actinobacteria,4D0JT@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00484 326426.Bbr_1320 0.0 927.0 COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria,4D0C1@85004|Bifidobacteriales 201174|Actinobacteria O SERine Proteinase INhibitors - - - ko:K13963 ko05146,map05146 - - - ko00000,ko00001 - - - Serpin BHPHKHDA_00485 216816.GS08_07060 8.6e-250 685.0 COG1609@1|root,COG1609@2|Bacteria,2GJY9@201174|Actinobacteria,4CYU5@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 BHPHKHDA_00486 401473.BDP_1602 1.8e-306 837.0 COG2807@1|root,COG2807@2|Bacteria,2GJRD@201174|Actinobacteria,4CYTK@85004|Bifidobacteriales 201174|Actinobacteria P LacY proton/sugar symporter lacY - - ko:K02532 - - - - ko00000,ko02000 2.A.1.5 - - LacY_symp BHPHKHDA_00487 326426.Bbr_1324 0.0 1040.0 COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 32 family fosC - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N BHPHKHDA_00488 326426.Bbr_1325 6.61e-181 503.0 COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CYR1@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family ppgK - 2.7.1.2,2.7.1.63 ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786,R02187,R02189 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK BHPHKHDA_00489 326426.Bbr_1326 8.77e-193 534.0 COG0778@1|root,COG0778@2|Bacteria,2IAH8@201174|Actinobacteria,4D04W@85004|Bifidobacteriales 201174|Actinobacteria C Putative TM nitroreductase - - - - - - - - - - - - TM1586_NiRdase BHPHKHDA_00490 326426.Bbr_1327 1.55e-252 691.0 COG1216@1|root,COG1216@2|Bacteria,2GMQQ@201174|Actinobacteria,4CZRJ@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 BHPHKHDA_00491 326426.Bbr_1328 4.04e-134 382.0 COG3601@1|root,COG3601@2|Bacteria,2IAX0@201174|Actinobacteria,4CZQD@85004|Bifidobacteriales 201174|Actinobacteria U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins - - - - - - - - - - - - ECF_trnsprt BHPHKHDA_00492 326426.Bbr_1329 0.0 1463.0 COG0619@1|root,COG1129@1|root,COG0619@2|Bacteria,COG1129@2|Bacteria,2I2G4@201174|Actinobacteria,4CZJE@85004|Bifidobacteriales 201174|Actinobacteria GP ABC transporter, ATP-binding protein - - - ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ BHPHKHDA_00493 326426.Bbr_1330 4.67e-63 193.0 COG1534@1|root,COG1534@2|Bacteria,2IKSS@201174|Actinobacteria,4D10K@85004|Bifidobacteriales 201174|Actinobacteria J CRS1_YhbY - - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY BHPHKHDA_00494 326426.Bbr_1331 1.66e-70 213.0 COG1950@1|root,COG1950@2|Bacteria,2HZND@201174|Actinobacteria,4D117@85004|Bifidobacteriales 201174|Actinobacteria S Mycobacterial 4 TMS phage holin, superfamily IV - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 BHPHKHDA_00495 1437609.BCAL_0492 2.26e-67 206.0 29SSD@1|root,30DYB@2|Bacteria,2IJ1J@201174|Actinobacteria,4D0SG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00496 326426.Bbr_1333 5.73e-239 656.0 COG0111@1|root,COG0111@2|Bacteria,2GP09@201174|Actinobacteria,4CZUN@85004|Bifidobacteriales 201174|Actinobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C BHPHKHDA_00497 326426.Bbr_1334 0.0 874.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZ0R@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr BHPHKHDA_00498 216816.GS08_07475 1.53e-41 152.0 COG5002@1|root,COG5002@2|Bacteria,2GJ2D@201174|Actinobacteria,4D03C@85004|Bifidobacteriales 201174|Actinobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain mtrB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.7.13.3 ko:K07636,ko:K07654 ko02020,map02020 M00434,M00461 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA BHPHKHDA_00499 216816.GS08_07480 2.53e-14 70.9 COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4D2SY@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal mtrA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K07670 ko02020,map02020 M00461 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BHPHKHDA_00500 326426.Bbr_1337 0.0 867.0 COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CZ2K@85004|Bifidobacteriales 201174|Actinobacteria L Recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N BHPHKHDA_00501 326426.Bbr_1338 0.0 1688.0 COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria,4CZVX@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase - - - - - - - - - - - - DEAD,DUF3516,Helicase_C BHPHKHDA_00502 326426.Bbr_1339 8.51e-254 696.0 COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4CZZU@85004|Bifidobacteriales 201174|Actinobacteria S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 BHPHKHDA_00503 326426.Bbr_1340 0.0 979.0 COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CZGJ@85004|Bifidobacteriales 201174|Actinobacteria EK Alanine-glyoxylate amino-transferase - - - ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 M00700,M00702 R01939 RC00006 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 - - - Aminotran_1_2,GntR BHPHKHDA_00504 326426.Bbr_1341 6.56e-145 409.0 COG1279@1|root,COG1279@2|Bacteria,2HZBK@201174|Actinobacteria,4CZJP@85004|Bifidobacteriales 201174|Actinobacteria S LysE type translocator - - - ko:K06895 - - - - ko00000,ko02000 2.A.75.1 - - LysE BHPHKHDA_00505 326426.Bbr_1342 0.0 1002.0 COG0671@1|root,COG0671@2|Bacteria,2I4ZG@201174|Actinobacteria,4CZ80@85004|Bifidobacteriales 201174|Actinobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2 BHPHKHDA_00506 326426.Bbr_1343 1.27e-252 694.0 COG0765@1|root,COG0765@2|Bacteria,2GNBH@201174|Actinobacteria,4CZB4@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component gluD - - ko:K10007 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - BPD_transp_1 BHPHKHDA_00507 326426.Bbr_1344 2.44e-143 406.0 COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4CZ5M@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component gluC - - ko:K10006 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - BPD_transp_1 BHPHKHDA_00508 326426.Bbr_1345 3.54e-186 518.0 COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4CZA4@85004|Bifidobacteriales 201174|Actinobacteria ET Belongs to the bacterial solute-binding protein 3 family gluB - - ko:K10005 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - SBP_bac_3 BHPHKHDA_00509 326426.Bbr_1346 6.38e-196 543.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CYXE@85004|Bifidobacteriales 201174|Actinobacteria E ATP-binding protein of ABC transporter for glutamate K02028 gluA - - ko:K10008 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.9 - - ABC_tran BHPHKHDA_00510 326426.Bbr_1347 5.22e-131 371.0 COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria,4D0MH@85004|Bifidobacteriales 201174|Actinobacteria S Aminoacyl-tRNA editing domain - - - - - - - - - - - - tRNA_edit BHPHKHDA_00511 326426.Bbr_1348 0.0 1205.0 COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CYWQ@85004|Bifidobacteriales 201174|Actinobacteria J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon BHPHKHDA_00512 216816.GS08_07550 0.0 877.0 COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CYR9@85004|Bifidobacteriales 201174|Actinobacteria J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His BHPHKHDA_00513 216816.GS08_07555 0.0 868.0 COG3266@1|root,COG3266@2|Bacteria,2I2EC@201174|Actinobacteria,4CYYM@85004|Bifidobacteriales 201174|Actinobacteria S Domain of Unknown Function (DUF349) - - - - - - - - - - - - DUF349 BHPHKHDA_00514 216816.GS08_07560 0.0 1099.0 COG0737@1|root,COG0737@2|Bacteria,2GKC3@201174|Actinobacteria,4D0CZ@85004|Bifidobacteriales 201174|Actinobacteria F 5'-nucleotidase, C-terminal domain - - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos BHPHKHDA_00515 216816.GS08_07565 4.49e-182 506.0 COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4CZW9@85004|Bifidobacteriales 201174|Actinobacteria S Creatinine amidohydrolase - - 3.5.2.10 ko:K01470 ko00330,map00330 - R01884 RC00615 ko00000,ko00001,ko01000 - - - Creatininase BHPHKHDA_00516 216816.GS08_07570 0.0 879.0 COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CYY8@85004|Bifidobacteriales 201174|Actinobacteria EGP Sugar (and other) transporter proP - - ko:K03762 - - - - ko00000,ko02000 2.A.1.6.4 - - MFS_1,Sugar_tr BHPHKHDA_00518 216816.GS08_07580 0.0 968.0 COG2508@1|root,COG2508@2|Bacteria,2HPPC@201174|Actinobacteria,4D0FM@85004|Bifidobacteriales 201174|Actinobacteria QT Purine catabolism regulatory protein-like family - - - - - - - - - - - - HTH_30,PucR BHPHKHDA_00519 326426.Bbr_1355 0.0 879.0 COG0402@1|root,COG0402@2|Bacteria,2GKKM@201174|Actinobacteria,4D07T@85004|Bifidobacteriales 201174|Actinobacteria F Amidohydrolase family codA - 3.5.4.1,3.5.4.21 ko:K01485,ko:K03365 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_3 BHPHKHDA_00520 326426.Bbr_1356 0.0 1650.0 COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CZCH@85004|Bifidobacteriales 201174|Actinobacteria O ATPase family associated with various cellular activities (AAA) clpC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR BHPHKHDA_00521 326426.Bbr_1357 2.31e-230 634.0 COG0589@1|root,COG0589@2|Bacteria,2IA7S@201174|Actinobacteria,4CZZ0@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the universal stress protein A family uspA - - - - - - - - - - - Usp BHPHKHDA_00522 326426.Bbr_1358 7.53e-241 663.0 28NWB@1|root,2ZBU7@2|Bacteria,2GJ74@201174|Actinobacteria,4CYW9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3027) - - - - - - - - - - - - DUF3027 BHPHKHDA_00523 326426.Bbr_1359 1.75e-87 257.0 COG1278@1|root,COG1278@2|Bacteria,2IKXN@201174|Actinobacteria,4D0V4@85004|Bifidobacteriales 201174|Actinobacteria K 'Cold-shock' DNA-binding domain cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD BHPHKHDA_00524 326426.Bbr_1360 0.0 1166.0 COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4CZNF@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein phoR - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA BHPHKHDA_00525 326426.Bbr_1361 2.48e-170 476.0 COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4CYPS@85004|Bifidobacteriales 201174|Actinobacteria KT Response regulator receiver domain protein phoP - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C BHPHKHDA_00526 326426.Bbr_1362 2.67e-148 423.0 2B59T@1|root,31Y3Y@2|Bacteria,2HZNR@201174|Actinobacteria,4D12Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - TPM_phosphatase BHPHKHDA_00527 326426.Bbr_1363 6.57e-54 169.0 COG4842@1|root,COG4842@2|Bacteria,2GQI8@201174|Actinobacteria,4D17K@85004|Bifidobacteriales 201174|Actinobacteria S Proteins of 100 residues with WXG - - - - - - - - - - - - WXG100 BHPHKHDA_00528 326426.Bbr_1364 0.0 1007.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales 201174|Actinobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 BHPHKHDA_00529 326426.Bbr_1365 1.54e-51 162.0 COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4D1FB@85004|Bifidobacteriales 201174|Actinobacteria K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD BHPHKHDA_00530 326426.Bbr_1366 8.33e-127 363.0 2DP6P@1|root,330SA@2|Bacteria,2GQYA@201174|Actinobacteria,4CZYT@85004|Bifidobacteriales 201174|Actinobacteria S LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C BHPHKHDA_00531 326426.Bbr_1367 8.09e-169 471.0 COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria,4CZ3Y@85004|Bifidobacteriales 201174|Actinobacteria L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG BHPHKHDA_00532 326426.Bbr_1368 1.53e-245 676.0 COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ2I@85004|Bifidobacteriales 201174|Actinobacteria S ATPase family associated with various cellular activities (AAA) moxR - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 BHPHKHDA_00533 326426.Bbr_1369 3.97e-210 582.0 COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4CYYD@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 BHPHKHDA_00534 326426.Bbr_1370 2.68e-118 339.0 2AUTC@1|root,31KGE@2|Bacteria,2IKRN@201174|Actinobacteria,4D134@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00535 326426.Bbr_1371 7.54e-242 665.0 COG2304@1|root,COG2304@2|Bacteria,2I9VM@201174|Actinobacteria,4CZ00@85004|Bifidobacteriales 201174|Actinobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 BHPHKHDA_00536 326426.Bbr_1372 4.24e-213 592.0 COG2304@1|root,COG2304@2|Bacteria,2GJMP@201174|Actinobacteria,4CZ8P@85004|Bifidobacteriales 201174|Actinobacteria S von Willebrand factor (vWF) type A domain - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2 BHPHKHDA_00537 326426.Bbr_1373 8.64e-76 232.0 2BG6D@1|root,32A37@2|Bacteria,2IR67@201174|Actinobacteria,4D18W@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00538 326426.Bbr_1375 0.0 965.0 COG1075@1|root,COG1075@2|Bacteria,2IHFB@201174|Actinobacteria,4CZ17@85004|Bifidobacteriales 201174|Actinobacteria S PGAP1-like protein - - - - - - - - - - - - Abhydrolase_6,Abhydrolase_8,PGAP1 BHPHKHDA_00539 326426.Bbr_1376 2.13e-143 405.0 COG4721@1|root,COG4721@2|Bacteria,2H5VZ@201174|Actinobacteria,4CZ6M@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type cobalt transport system, permease component - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt BHPHKHDA_00540 326426.Bbr_1377 0.0 953.0 COG0015@1|root,COG0015@2|Bacteria,2GM71@201174|Actinobacteria,4CYV6@85004|Bifidobacteriales 201174|Actinobacteria F Adenylosuccinate lyase C-terminal purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ASL_C,Lyase_1 BHPHKHDA_00541 326426.Bbr_1378 0.0 1600.0 COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4CYRT@85004|Bifidobacteriales 201174|Actinobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM BHPHKHDA_00542 326426.Bbr_1379 3.31e-57 177.0 COG0776@1|root,COG0776@2|Bacteria,2IKQR@201174|Actinobacteria,4D11V@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the bacterial histone-like protein family hup GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding BHPHKHDA_00543 326426.Bbr_1380 0.0 977.0 COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CZ12@85004|Bifidobacteriales 201174|Actinobacteria O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine pafA GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 ko:K13571 - M00342 R11207 RC00090,RC00096 ko00000,ko00002,ko01000,ko03051 - - - Pup_ligase BHPHKHDA_00544 326426.Bbr_1381 8.43e-16 71.2 2B5FT@1|root,31YAF@2|Bacteria,2GV5R@201174|Actinobacteria,4D1NH@85004|Bifidobacteriales 201174|Actinobacteria S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation pup - - ko:K13570 - - - - ko00000,ko04121 - - - Pup BHPHKHDA_00545 326426.Bbr_1382 4.8e-224 616.0 COG0483@1|root,COG0483@2|Bacteria,2HGP2@201174|Actinobacteria,4CYWZ@85004|Bifidobacteriales 201174|Actinobacteria G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P BHPHKHDA_00546 326426.Bbr_1383 0.0 1100.0 COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4CZAN@85004|Bifidobacteriales 201174|Actinobacteria S Pup-ligase protein dop GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 ko:K20814 - - - - ko00000,ko01000,ko03051 - - - Pup_ligase BHPHKHDA_00547 326426.Bbr_1384 4.32e-173 482.0 COG0036@1|root,COG0036@2|Bacteria,2IC1U@201174|Actinobacteria,4CZWV@85004|Bifidobacteriales 201174|Actinobacteria G Ribulose-phosphate 3 epimerase family - - - ko:K17195 ko00051,ko01120,map00051,map01120 - R09031 RC03111 ko00000,ko00001,ko01000 - - - Ribul_P_3_epim BHPHKHDA_00548 326426.Bbr_1385 4.16e-229 635.0 COG1299@1|root,COG1299@2|Bacteria,2GJU4@201174|Actinobacteria,4CZ60@85004|Bifidobacteriales 201174|Actinobacteria G Phosphotransferase System - - - ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 - - PTS_EIIC BHPHKHDA_00549 326426.Bbr_1386 2.2e-62 191.0 COG1445@1|root,COG1445@2|Bacteria,2IPEN@201174|Actinobacteria,4D113@85004|Bifidobacteriales 201174|Actinobacteria G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.202 ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_IIB BHPHKHDA_00550 326426.Bbr_1387 5.44e-104 301.0 COG1762@1|root,COG1762@2|Bacteria,2IMPP@201174|Actinobacteria,4D0WI@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 BHPHKHDA_00551 326426.Bbr_1388 3.14e-94 275.0 2BIQA@1|root,32CXN@2|Bacteria,2GTDU@201174|Actinobacteria,4D1IN@85004|Bifidobacteriales 201174|Actinobacteria H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - PTS_EIIA_2 BHPHKHDA_00552 326426.Bbr_1389 0.0 966.0 COG3711@1|root,COG3711@2|Bacteria,2HXN0@201174|Actinobacteria,4D049@85004|Bifidobacteriales 201174|Actinobacteria K PRD domain - - - ko:K02538,ko:K03483,ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB BHPHKHDA_00553 326426.Bbr_1390 4.48e-170 474.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4CZGV@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase BHPHKHDA_00554 326426.Bbr_1391 0.0 990.0 COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CZ86@85004|Bifidobacteriales 201174|Actinobacteria O AAA ATPase forming ring-shaped complexes arc GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - ko:K13527 ko03050,map03050 M00342 - - ko00000,ko00001,ko00002,ko03051 - - - AAA,Prot_ATP_ID_OB BHPHKHDA_00555 326426.Bbr_1392 3.4e-162 454.0 COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4CZZA@85004|Bifidobacteriales 201174|Actinobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc BHPHKHDA_00556 326426.Bbr_1393 3.93e-152 429.0 COG0560@1|root,COG0560@2|Bacteria,2GJDH@201174|Actinobacteria,4CYWC@85004|Bifidobacteriales 201174|Actinobacteria E haloacid dehalogenase-like hydrolase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD BHPHKHDA_00557 326426.Bbr_1394 0.0 1491.0 COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,4D04J@85004|Bifidobacteriales 201174|Actinobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - - BHPHKHDA_00558 326426.Bbr_1395 8.38e-169 471.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4CZGV@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 BHPHKHDA_00559 326426.Bbr_1396 1.51e-234 646.0 COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CZ8C@85004|Bifidobacteriales 201174|Actinobacteria J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0040007,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N BHPHKHDA_00560 158787.BSCA_2034 0.0 1173.0 COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CZ1T@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD BHPHKHDA_00561 326426.Bbr_1398 5.45e-61 187.0 COG1758@1|root,COG1758@2|Bacteria,2IQHU@201174|Actinobacteria,4D12C@85004|Bifidobacteriales 201174|Actinobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 BHPHKHDA_00562 326426.Bbr_1399 1.67e-291 796.0 COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4CZ5D@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N BHPHKHDA_00563 326426.Bbr_1400 4.94e-211 582.0 COG3177@1|root,COG3177@2|Bacteria,2ICFW@201174|Actinobacteria,4D07M@85004|Bifidobacteriales 201174|Actinobacteria G Fic/DOC family - - - - - - - - - - - - Fic,HTH_26 BHPHKHDA_00564 216816.GS08_05855 1.11e-24 94.0 COG4974@1|root,COG4974@2|Bacteria 2|Bacteria L Belongs to the 'phage' integrase family - - - ko:K07484 - - - - ko00000 - - - Arm-DNA-bind_5,DDE_Tnp_IS66,DDE_Tnp_IS66_C BHPHKHDA_00565 903818.KI912268_gene3246 5.53e-17 88.6 COG3550@1|root,COG3550@2|Bacteria,3Y4V9@57723|Acidobacteria 57723|Acidobacteria S HipA N-terminal domain - - 2.7.11.1 ko:K07154 - - - - ko00000,ko01000,ko01001,ko02048 - - - Couple_hipA,HipA_C BHPHKHDA_00567 158787.BSCA_1054 5.3e-08 53.1 COG5340@1|root,COG5340@2|Bacteria,2IMTJ@201174|Actinobacteria,4D150@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - BHPHKHDA_00570 216816.GS08_05830 2.79e-180 502.0 COG3177@1|root,COG3177@2|Bacteria,2GW8P@201174|Actinobacteria,4D1U2@85004|Bifidobacteriales 201174|Actinobacteria S Fic/DOC family - - - - - - - - - - - - Fic BHPHKHDA_00571 1688.BCUN_0730 2.26e-176 507.0 COG0323@1|root,COG0323@2|Bacteria,2GPWU@201174|Actinobacteria,4CZXB@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Relaxase mobilization nuclease family protein - - - - - - - - - - - - Relaxase BHPHKHDA_00572 641146.HMPREF9020_01337 1.4e-140 397.0 COG1309@1|root,COG1309@2|Bacteria,2HZES@201174|Actinobacteria,4D04U@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N BHPHKHDA_00573 641146.HMPREF9020_01336 1.33e-160 450.0 COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00574 641146.HMPREF9020_01335 0.0 1415.0 COG0577@1|root,COG0577@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BHPHKHDA_00576 326426.Bbr_1123 1.32e-249 685.0 COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CZ0K@85004|Bifidobacteriales 201174|Actinobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Acetyltransf_1,Peptidase_M22 BHPHKHDA_00577 326426.Bbr_1124 3.32e-135 383.0 COG0454@1|root,COG0456@2|Bacteria,2IM9R@201174|Actinobacteria,4D0Q0@85004|Bifidobacteriales 201174|Actinobacteria K FR47-like protein rimI GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 BHPHKHDA_00578 326426.Bbr_1125 1.39e-201 559.0 COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,4D0A2@85004|Bifidobacteriales 201174|Actinobacteria O Glycoprotease family yeaZ GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - ko:K14742 - - - - ko00000,ko03016 - - - Peptidase_M22 BHPHKHDA_00579 216816.GS08_05880 8.71e-112 323.0 COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4D0PH@85004|Bifidobacteriales 201174|Actinobacteria S Threonylcarbamoyl adenosine biosynthesis protein TsaE tsaE GO:0008150,GO:0040007 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE BHPHKHDA_00580 326426.Bbr_1127 2.06e-220 608.0 COG1466@1|root,COG1466@2|Bacteria,2GNMZ@201174|Actinobacteria,4CZ07@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta BHPHKHDA_00581 326426.Bbr_1128 0.0 1083.0 COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria,4CZ6X@85004|Bifidobacteriales 201174|Actinobacteria S Competence protein comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B BHPHKHDA_00582 326426.Bbr_1129 9.69e-143 406.0 COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4D176@85004|Bifidobacteriales 201174|Actinobacteria L Helix-hairpin-helix motif comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB BHPHKHDA_00583 326426.Bbr_1130 0.0 2051.0 COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4CZHV@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 BHPHKHDA_00584 326426.Bbr_1131 6.18e-205 567.0 COG0834@1|root,COG0834@2|Bacteria,2I9PU@201174|Actinobacteria,4D09U@85004|Bifidobacteriales 201174|Actinobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K10005 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - SBP_bac_3 BHPHKHDA_00585 326426.Bbr_1132 4.06e-217 600.0 COG0598@1|root,COG0598@2|Bacteria,2HZ8V@201174|Actinobacteria,4CYWX@85004|Bifidobacteriales 201174|Actinobacteria P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA BHPHKHDA_00586 326426.Bbr_1133 2.1e-215 593.0 COG0406@1|root,COG0406@2|Bacteria,2GJYU@201174|Actinobacteria,4CZI8@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpmB GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0044237 3.1.3.85,5.4.2.11 ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 BHPHKHDA_00587 326426.Bbr_1134 4.05e-294 803.0 COG0742@1|root,COG0742@2|Bacteria,2HZAY@201174|Actinobacteria,4CZEU@85004|Bifidobacteriales 201174|Actinobacteria L ribosomal rna small subunit methyltransferase - - - - - - - - - - - - Cons_hypoth95,Methyltransf_15,PCMT BHPHKHDA_00588 216816.GS08_05925 2.35e-92 270.0 COG3576@1|root,COG3576@2|Bacteria,2IJK2@201174|Actinobacteria,4D0W8@85004|Bifidobacteriales 201174|Actinobacteria S Pfam:Pyridox_oxidase pdxH - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx BHPHKHDA_00589 326426.Bbr_1136 1.12e-216 598.0 COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D011@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA BHPHKHDA_00590 326426.Bbr_1137 4.85e-167 466.0 COG0778@1|root,COG0778@2|Bacteria,2GP9P@201174|Actinobacteria,4CZGH@85004|Bifidobacteriales 201174|Actinobacteria C Putative TM nitroreductase - - - - - - - - - - - - TM1586_NiRdase BHPHKHDA_00591 1437610.BREU_1546 8.47e-42 157.0 2DQFC@1|root,336HV@2|Bacteria,2I8B6@201174|Actinobacteria,4D309@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00592 326426.Bbr_1139 0.0 882.0 COG3538@1|root,COG3538@2|Bacteria,2HHAF@201174|Actinobacteria,4CZYN@85004|Bifidobacteriales 201174|Actinobacteria S Metal-independent alpha-mannosidase (GH125) - - - ko:K09704 - - - - ko00000 - - - Glyco_hydro_125 BHPHKHDA_00593 326426.Bbr_1140 5.35e-311 845.0 COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4CZNY@85004|Bifidobacteriales 201174|Actinobacteria G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - - - - - - - - - - GlcNAc_2-epim BHPHKHDA_00594 326426.Bbr_1141 2.45e-262 719.0 COG1609@1|root,COG1609@2|Bacteria,2GJHF@201174|Actinobacteria,4CZCC@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_00595 326426.Bbr_1142 0.0 1860.0 COG3291@1|root,COG4724@1|root,COG3291@2|Bacteria,COG4724@2|Bacteria,2GIRN@201174|Actinobacteria,4D0D5@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 85 - - 3.2.1.96 ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - F5_F8_type_C,Glyco_hydro_85 BHPHKHDA_00596 326426.Bbr_1143 0.0 1746.0 COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4D005@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - DUF5110,Glyco_hydro_31 BHPHKHDA_00597 326426.Bbr_1144 0.0 905.0 COG3934@1|root,COG3934@2|Bacteria,2GNN6@201174|Actinobacteria,4CZEH@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase BHPHKHDA_00598 326426.Bbr_1145 7.2e-200 554.0 COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4D014@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00599 326426.Bbr_1146 2.78e-222 613.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0DM@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K17330 ko02010,map02010 M00207,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.33 - - BPD_transp_1 BHPHKHDA_00600 326426.Bbr_1147 1.01e-312 851.0 COG1653@1|root,COG1653@2|Bacteria,2GJSR@201174|Actinobacteria,4D08C@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_00601 326426.Bbr_1148 0.0 2091.0 COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4CYWB@85004|Bifidobacteriales 201174|Actinobacteria G Alpha mannosidase, middle domain - - 3.2.1.24 ko:K01191 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04131 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C BHPHKHDA_00602 326426.Bbr_1149 0.0 2075.0 COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4CYWB@85004|Bifidobacteriales 201174|Actinobacteria G Alpha mannosidase, middle domain - - 3.2.1.24 ko:K01191 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04131 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C BHPHKHDA_00603 216816.GS08_06690 0.0 2041.0 COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4CYWB@85004|Bifidobacteriales 201174|Actinobacteria G Alpha mannosidase, middle domain - - 3.2.1.24 ko:K01191 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04131 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C BHPHKHDA_00604 216816.GS08_06695 4.78e-110 317.0 COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria,4D0VE@85004|Bifidobacteriales 201174|Actinobacteria J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase BHPHKHDA_00605 1437609.BCAL_1036 2.3e-62 202.0 COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4D01A@85004|Bifidobacteriales 201174|Actinobacteria S Appr-1'-p processing enzyme lppD GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Macro BHPHKHDA_00606 1034345.CAEM01000015_gene277 1.48e-36 127.0 28NY7@1|root,2ZBVG@2|Bacteria,2GRNZ@201174|Actinobacteria,4CW8T@84998|Coriobacteriia 84998|Coriobacteriia S Protein of unknown function (DUF2992) - - - - - - - - - - - - DUF2992 BHPHKHDA_00607 1034345.CAEM01000015_gene276 5.62e-226 623.0 COG4823@1|root,COG4823@2|Bacteria,2H1AS@201174|Actinobacteria,4CVUI@84998|Coriobacteriia 84998|Coriobacteriia V Abi-like protein - - - - - - - - - - - - Abi_2 BHPHKHDA_00608 326426.Bbr_0774 0.0 1216.0 COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4D0BY@85004|Bifidobacteriales 201174|Actinobacteria I Psort location CytoplasmicMembrane, score 9.99 yrhL - - - - - - - - - - - Acyl_transf_3 BHPHKHDA_00609 326426.Bbr_0773 1.37e-244 672.0 COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CYRD@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N BHPHKHDA_00611 326426.Bbr_0772 0.0 1084.0 COG0280@1|root,COG0280@2|Bacteria,2GJ5U@201174|Actinobacteria,4CZE6@85004|Bifidobacteriales 201174|Actinobacteria C phosphate acetyltransferase pta GO:0005575,GO:0005576 2.3.1.8 ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000 - - - AAA_26,DRTGG,PTA_PTB BHPHKHDA_00612 326426.Bbr_0771 1.89e-294 803.0 COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4CZ7V@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0409 Acetate_kinase BHPHKHDA_00613 326426.Bbr_0770 0.0 868.0 COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4CZBG@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase BHPHKHDA_00614 326426.Bbr_0769 3.26e-274 751.0 2DSXT@1|root,32UTZ@2|Bacteria,2GKR7@201174|Actinobacteria,4CZBW@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF998 BHPHKHDA_00616 216816.GS08_03800 2.57e-27 103.0 COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,4D0ZA@85004|Bifidobacteriales 201174|Actinobacteria L Methyladenine glycosylase - - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco BHPHKHDA_00618 216816.GS08_03790 2.24e-155 436.0 COG4832@1|root,COG4832@2|Bacteria,2GN4K@201174|Actinobacteria,4D08M@85004|Bifidobacteriales 201174|Actinobacteria S GyrI-like small molecule binding domain - - - - - - - - - - - - GyrI-like BHPHKHDA_00619 216816.GS08_03785 3.52e-116 332.0 COG1476@1|root,COG1476@2|Bacteria,2IGPZ@201174|Actinobacteria,4D0N7@85004|Bifidobacteriales 201174|Actinobacteria K Putative zinc ribbon domain - - - - - - - - - - - - HTH_3,TipAS,Zn_ribbon_2 BHPHKHDA_00620 216816.GS08_03780 9.31e-36 121.0 COG0789@1|root,COG0789@2|Bacteria 2|Bacteria K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding zntR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 BHPHKHDA_00621 326426.Bbr_0763 0.0 1442.0 COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CZGR@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 BHPHKHDA_00622 326426.Bbr_0762 4.87e-163 456.0 COG0494@1|root,COG0494@2|Bacteria,2IIY0@201174|Actinobacteria,4D0P8@85004|Bifidobacteriales 201174|Actinobacteria L NUDIX domain - - - - - - - - - - - - NUDIX BHPHKHDA_00623 326426.Bbr_0761 4.64e-227 624.0 COG0327@1|root,COG0327@2|Bacteria,2GKHZ@201174|Actinobacteria,4CYXC@85004|Bifidobacteriales 201174|Actinobacteria L NIF3 (NGG1p interacting factor 3) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 BHPHKHDA_00624 326426.Bbr_0760 0.0 1855.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,4CYVK@85004|Bifidobacteriales 201174|Actinobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 BHPHKHDA_00625 326426.Bbr_0759 2.41e-166 467.0 COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CYS7@85004|Bifidobacteriales 201174|Actinobacteria T Response regulator receiver domain protein pdtaR GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - ko:K22010 - M00839 - - ko00000,ko00002,ko02022 - - - ANTAR,Response_reg BHPHKHDA_00627 326426.Bbr_0758 1.59e-138 392.0 COG0494@1|root,COG0494@2|Bacteria,2HEH8@201174|Actinobacteria,4CZD0@85004|Bifidobacteriales 201174|Actinobacteria L NUDIX domain aspA - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX BHPHKHDA_00628 326426.Bbr_0757 0.0 946.0 COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CZA8@85004|Bifidobacteriales 201174|Actinobacteria G Pyruvate kinase pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C BHPHKHDA_00629 326426.Bbr_0756 3.81e-228 629.0 COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria,4CYW2@85004|Bifidobacteriales 201174|Actinobacteria P Integral membrane protein, TerC family terC - - ko:K05794 - - - - ko00000 - - - TerC BHPHKHDA_00630 326426.Bbr_0755 0.0 1372.0 COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,4CZR0@85004|Bifidobacteriales 201174|Actinobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB BHPHKHDA_00631 326426.Bbr_0754 1.18e-134 383.0 COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4D0PG@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE,GrpB BHPHKHDA_00632 326426.Bbr_0753 0.0 898.0 COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein S1 rpsA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 BHPHKHDA_00633 326426.Bbr_0752 3.6e-208 575.0 COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria,4CZ53@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0040007,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C BHPHKHDA_00634 326426.Bbr_0751 7.52e-264 724.0 COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales 201174|Actinobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA BHPHKHDA_00635 326426.Bbr_0750 1.5e-205 569.0 COG1121@1|root,COG1121@2|Bacteria,2GP3A@201174|Actinobacteria,4CZEV@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02074 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC_tran BHPHKHDA_00636 326426.Bbr_0749 1.1e-174 489.0 COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,4CYTG@85004|Bifidobacteriales 201174|Actinobacteria U ABC 3 transport family znuB - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 BHPHKHDA_00637 326426.Bbr_0748 1.77e-114 328.0 COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4D0X6@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB BHPHKHDA_00638 326426.Bbr_0747 2.16e-130 371.0 COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CZXD@85004|Bifidobacteriales 201174|Actinobacteria K CarD-like/TRCF domain carD GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF BHPHKHDA_00639 326426.Bbr_0746 0.0 1543.0 COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CZMD@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 BHPHKHDA_00640 326426.Bbr_0745 3.51e-164 460.0 COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CZS5@85004|Bifidobacteriales 201174|Actinobacteria T Response regulator receiver domain protein cseB - - - - - - - - - - - Response_reg,Trans_reg_C BHPHKHDA_00641 326426.Bbr_0744 4.09e-249 684.0 COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4CZNA@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - - - - - - - - - - HAMP,HATPase_c,HisKA BHPHKHDA_00642 326426.Bbr_0743 5.28e-158 443.0 COG1040@1|root,COG1040@2|Bacteria,2I9PA@201174|Actinobacteria,4D11A@85004|Bifidobacteriales 201174|Actinobacteria S Phosphoribosyl transferase domain pyrE_1 - - - - - - - - - - - Pribosyltran BHPHKHDA_00643 326426.Bbr_0742 2.92e-190 528.0 COG0561@1|root,COG0561@2|Bacteria,2HZD0@201174|Actinobacteria,4CZ4N@85004|Bifidobacteriales 201174|Actinobacteria T Eukaryotic phosphomannomutase - - - - - - - - - - - - Hydrolase_3,PMM BHPHKHDA_00644 326426.Bbr_0741 2.13e-101 293.0 COG3824@1|root,COG3824@2|Bacteria,2IS6W@201174|Actinobacteria,4D0YK@85004|Bifidobacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_1 BHPHKHDA_00645 326426.Bbr_0740 0.0 917.0 2EC47@1|root,33QBB@2|Bacteria,2I2HY@201174|Actinobacteria,4D2VU@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00646 326426.Bbr_0739 0.0 1960.0 COG1216@1|root,COG5617@1|root,COG1216@2|Bacteria,COG5617@2|Bacteria,2I2FX@201174|Actinobacteria,4CYVM@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase, family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3 BHPHKHDA_00647 326426.Bbr_0738 2.06e-74 221.0 2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4D12I@85004|Bifidobacteriales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB2 - - ko:K18955 - - - - ko00000,ko03000 - - - Whib BHPHKHDA_00648 326426.Bbr_0737 2.54e-303 829.0 COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CYQY@85004|Bifidobacteriales 201174|Actinobacteria K Cell envelope-related transcriptional attenuator domain lytR2 - - - - - - - - - - - LytR_cpsA_psr BHPHKHDA_00649 326426.Bbr_0736 0.0 1120.0 COG1674@1|root,COG1674@2|Bacteria,2GJBR@201174|Actinobacteria,4CYU3@85004|Bifidobacteriales 201174|Actinobacteria D FtsK/SpoIIIE family - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Yop-YscD_cpl BHPHKHDA_00650 326426.Bbr_0735 8.13e-62 189.0 2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,4D11W@85004|Bifidobacteriales 201174|Actinobacteria K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA whiB GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K18955 - - - - ko00000,ko03000 - - - Whib BHPHKHDA_00651 326426.Bbr_0734 0.0 967.0 COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CYV1@85004|Bifidobacteriales 201174|Actinobacteria T ATPase histidine kinase DNA gyrase B HSP90 domain protein pdtaS GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 ko:K00936 - M00839 - - ko00000,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,H_kinase_N,HisKA_2,PAS_4 BHPHKHDA_00652 326426.Bbr_0733 9.75e-192 536.0 COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4CZGT@85004|Bifidobacteriales 201174|Actinobacteria S Haemolysin-III related hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII BHPHKHDA_00653 326426.Bbr_0732 7.1e-106 306.0 COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,4D0QM@85004|Bifidobacteriales 201174|Actinobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N BHPHKHDA_00654 326426.Bbr_0731 8.17e-98 283.0 COG0545@1|root,COG0545@2|Bacteria,2GJK2@201174|Actinobacteria,4D0V6@85004|Bifidobacteriales 201174|Actinobacteria G Peptidyl-prolyl cis-trans fkbP - 5.2.1.8 ko:K01802 - - - - ko00000,ko01000 - - - FKBP_C BHPHKHDA_00655 326426.Bbr_0730 0.0 969.0 COG1760@1|root,COG1760@2|Bacteria,2GJPA@201174|Actinobacteria,4CZ6I@85004|Bifidobacteriales 201174|Actinobacteria E Serine dehydratase alpha chain sdaA GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha,SDH_beta BHPHKHDA_00656 326426.Bbr_0729 2.34e-121 347.0 2ASIR@1|root,31HZA@2|Bacteria,2IHD9@201174|Actinobacteria,4D0QP@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00657 1435051.BMOU_0751 6.99e-50 171.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZKR@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family int8 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase BHPHKHDA_00658 1437608.BBIA_2190 8.98e-109 326.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZKR@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family int8 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase BHPHKHDA_00664 158787.BSCA_0773 2.33e-44 147.0 2C5TS@1|root,2ZX0Y@2|Bacteria,2IT81@201174|Actinobacteria,4D1BF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00665 158787.BSCA_0773 2.07e-11 62.4 2C5TS@1|root,2ZX0Y@2|Bacteria,2IT81@201174|Actinobacteria,4D1BF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00666 1680.BADO_1636 2.76e-149 436.0 COG3177@1|root,COG3177@2|Bacteria,2HZGJ@201174|Actinobacteria,4D0D3@85004|Bifidobacteriales 201174|Actinobacteria K Fic/DOC family - - - - - - - - - - - - Fic BHPHKHDA_00667 158787.BSCA_0771 2.64e-08 55.5 2DEKP@1|root,2ZNCE@2|Bacteria,2GWQJ@201174|Actinobacteria,4D1NS@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00668 216816.GS08_04810 1.1e-34 140.0 COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - rve BHPHKHDA_00669 216816.GS08_04810 2.65e-59 196.0 COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - rve BHPHKHDA_00670 401473.BDP_2169 7.81e-187 524.0 COG1609@1|root,COG1609@2|Bacteria,2GMHV@201174|Actinobacteria,4CZ3G@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor scrR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 BHPHKHDA_00671 401473.BDP_2170 6.48e-300 823.0 COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria,4CZ8W@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N BHPHKHDA_00672 401473.BDP_2171 0.0 895.0 COG4030@1|root,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4CZ06@85004|Bifidobacteriales 201174|Actinobacteria M Protein of unknown function (DUF2961) - - - - - - - - - - - - DUF2961 BHPHKHDA_00673 401473.BDP_2172 3.03e-165 465.0 COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4D0VJ@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport systems inner membrane component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_00674 1437603.BMON_1764 3.86e-161 456.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4D0JI@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10118 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_00675 401473.BDP_2174 5.11e-267 736.0 COG1653@1|root,COG1653@2|Bacteria,2ICAE@201174|Actinobacteria,4CZHF@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_00676 78346.BRUM_1707 7.8e-115 331.0 COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria,4CZNP@85004|Bifidobacteriales 201174|Actinobacteria L Resolvase, N terminal domain - - - - - - - - - - - - HTH_7,Resolvase BHPHKHDA_00677 1193128.A200_08258 1.22e-59 191.0 COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_23,HTH_28 BHPHKHDA_00678 1193128.A200_08253 1.05e-102 301.0 COG2801@1|root,COG2801@2|Bacteria,2H928@201174|Actinobacteria,4CZCP@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 BHPHKHDA_00679 78346.BRUM_1710 5.87e-102 305.0 COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4CYXY@85004|Bifidobacteriales 201174|Actinobacteria L HTH-like domain - - - - - - - - - - - - HTH_21,rve BHPHKHDA_00681 326426.Bbr_0728 9.07e-234 644.0 COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4CZCS@85004|Bifidobacteriales 201174|Actinobacteria FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA BHPHKHDA_00682 326426.Bbr_0727 2.77e-133 377.0 COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,4CZQX@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF501) - - - ko:K09009 - - - - ko00000 - - - DUF501 BHPHKHDA_00683 326426.Bbr_0726 1.51e-103 303.0 COG2919@1|root,COG2919@2|Bacteria,2IR5G@201174|Actinobacteria,4D0SS@85004|Bifidobacteriales 201174|Actinobacteria D Septum formation initiator - - - - - - - - - - - - DivIC BHPHKHDA_00684 326426.Bbr_0725 2.49e-313 853.0 COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CYT3@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N BHPHKHDA_00685 326426.Bbr_0724 1.82e-227 625.0 COG0667@1|root,COG0667@2|Bacteria,2GJ6R@201174|Actinobacteria,4CZ9P@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red BHPHKHDA_00686 326426.Bbr_0723 0.0 2261.0 COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,4CZ8X@85004|Bifidobacteriales 201174|Actinobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF BHPHKHDA_00687 326426.Bbr_0722 3.48e-146 411.0 COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,4CZBE@85004|Bifidobacteriales 201174|Actinobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro BHPHKHDA_00688 326426.Bbr_0721 7.51e-118 338.0 COG1247@1|root,COG1247@2|Bacteria,2HZCB@201174|Actinobacteria,4CZQI@85004|Bifidobacteriales 201174|Actinobacteria M Acetyltransferase (GNAT) domain - - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 BHPHKHDA_00689 326426.Bbr_0720 0.0 1856.0 COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CYW1@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised protein family (UPF0182) - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K09118 - - - - ko00000 - - - UPF0182 BHPHKHDA_00691 398513.BBNG_01272 2.65e-194 541.0 COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales 201174|Actinobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA BHPHKHDA_00693 702459.BBPR_1325 3.76e-213 595.0 COG0701@1|root,COG0701@2|Bacteria,2GJQ0@201174|Actinobacteria,4D057@85004|Bifidobacteriales 201174|Actinobacteria S Predicted permease - - - ko:K07089 - - - - ko00000 - - - ArsP_1 BHPHKHDA_00694 398513.BBNG_01280 1.15e-164 464.0 COG3689@1|root,COG3689@2|Bacteria,2I8JS@201174|Actinobacteria,4CZZQ@85004|Bifidobacteriales 201174|Actinobacteria S TIGRFAM TIGR03943 family protein - - - - - - - - - - - - DUF1980 BHPHKHDA_00695 326426.Bbr_0718 5.25e-176 490.0 COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CZ82@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like BHPHKHDA_00696 326426.Bbr_0717 1.26e-124 355.0 2A13J@1|root,30P9F@2|Bacteria,2GKGD@201174|Actinobacteria,4D0QR@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00697 326426.Bbr_0716 4.49e-298 815.0 COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4CZ2H@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2427c Aldedh BHPHKHDA_00698 326426.Bbr_0715 0.0 979.0 COG0498@1|root,COG0498@2|Bacteria,2GIRY@201174|Actinobacteria,4CYS0@85004|Bifidobacteriales 201174|Actinobacteria E Threonine synthase N terminus thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N BHPHKHDA_00699 216816.GS08_03475 1.36e-250 690.0 COG4194@1|root,COG4194@2|Bacteria,2IBNS@201174|Actinobacteria,4CZJU@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1648) - - - - - - - - - - - - DUF1648 BHPHKHDA_00700 216816.GS08_03470 1.07e-93 274.0 COG1725@1|root,COG1725@2|Bacteria,2IMER@201174|Actinobacteria,4D16Q@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR BHPHKHDA_00701 216816.GS08_03455 3.61e-37 128.0 COG0474@1|root,COG0474@2|Bacteria 2|Bacteria P ATPase, P-type transporting, HAD superfamily, subfamily IC pacL2 - 3.6.3.8 ko:K01537,ko:K12955 - - - - ko00000,ko01000 3.A.3.2,3.A.3.24 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 BHPHKHDA_00702 216816.GS08_03450 4.04e-125 361.0 2B3RX@1|root,31PYJ@2|Bacteria,2IRDS@201174|Actinobacteria,4D16Y@85004|Bifidobacteriales 201174|Actinobacteria S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 BHPHKHDA_00703 326426.Bbr_0713 1.94e-155 437.0 2ARYF@1|root,31HAF@2|Bacteria,2IK3T@201174|Actinobacteria,4D0YH@85004|Bifidobacteriales 201174|Actinobacteria S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 BHPHKHDA_00704 326426.Bbr_0712 1.32e-222 613.0 COG1131@1|root,COG1131@2|Bacteria,2GRE8@201174|Actinobacteria,4CZBH@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00705 326426.Bbr_0711 3.46e-78 233.0 COG1725@1|root,COG1725@2|Bacteria,2IQEW@201174|Actinobacteria,4D152@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix gluconate operon transcriptional repressor - - - ko:K07979 - - - - ko00000,ko03000 - - - GntR BHPHKHDA_00706 1437609.BCAL_0838 1.32e-23 95.5 COG1670@1|root,COG1670@2|Bacteria,2HZK6@201174|Actinobacteria,4D0RS@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 BHPHKHDA_00707 1437609.BCAL_0838 1.37e-17 79.7 COG1670@1|root,COG1670@2|Bacteria,2HZK6@201174|Actinobacteria,4D0RS@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 BHPHKHDA_00708 326426.Bbr_0709 1.34e-151 426.0 COG0637@1|root,COG0637@2|Bacteria,2I362@201174|Actinobacteria,4CZ8D@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 BHPHKHDA_00709 326426.Bbr_0708 0.0 1094.0 COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CYYF@85004|Bifidobacteriales 201174|Actinobacteria L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N BHPHKHDA_00710 326426.Bbr_0707 9.09e-235 645.0 COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CYZ0@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase BHPHKHDA_00711 216816.GS08_03415 4.29e-50 174.0 COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria,4CZH7@85004|Bifidobacteriales 201174|Actinobacteria P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH BHPHKHDA_00712 216816.GS08_03410 1.25e-64 202.0 COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria,4CZVT@85004|Bifidobacteriales 201174|Actinobacteria P TrkA-N domain trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N BHPHKHDA_00713 326426.Bbr_0704 7.68e-151 425.0 2B0CX@1|root,31SQ3@2|Bacteria,2GR13@201174|Actinobacteria,4D1JN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00714 326426.Bbr_0703 1.28e-179 500.0 COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CZSS@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal RNA large subunit methyltransferase J tlyA GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 BHPHKHDA_00716 326426.Bbr_0702 2.4e-257 704.0 COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CZ1Z@85004|Bifidobacteriales 201174|Actinobacteria G Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_6,Hydrolase_like BHPHKHDA_00717 326426.Bbr_0701 7.66e-308 854.0 COG0457@1|root,COG0457@2|Bacteria,2GKX5@201174|Actinobacteria,4CYXN@85004|Bifidobacteriales 201174|Actinobacteria L Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 BHPHKHDA_00718 326426.Bbr_0700 0.0 879.0 COG0162@1|root,COG0162@2|Bacteria,2GJPR@201174|Actinobacteria,4CZKG@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b BHPHKHDA_00719 326426.Bbr_0699 2.29e-98 305.0 COG4905@1|root,COG5523@1|root,COG4905@2|Bacteria,COG5523@2|Bacteria,2IB0C@201174|Actinobacteria,4D0E9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF975) - - - - - - - - - - - - ABC_trans_CmpB,DUF975 BHPHKHDA_00720 326426.Bbr_0698 9.39e-181 503.0 COG4905@1|root,COG4905@2|Bacteria,2IA3M@201174|Actinobacteria,4CZY7@85004|Bifidobacteriales 201174|Actinobacteria S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB BHPHKHDA_00721 326426.Bbr_0697 6.92e-133 375.0 COG1418@1|root,COG1418@2|Bacteria,2IFXP@201174|Actinobacteria,4D0P2@85004|Bifidobacteriales 201174|Actinobacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K06950 - - - - ko00000 - - - HD BHPHKHDA_00722 326426.Bbr_0696 5.26e-84 248.0 COG0607@1|root,COG0607@2|Bacteria,2ISA2@201174|Actinobacteria,4D2SX@85004|Bifidobacteriales 201174|Actinobacteria P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese BHPHKHDA_00723 326426.Bbr_0695 1.62e-188 524.0 COG0476@1|root,COG0476@2|Bacteria,2GJB6@201174|Actinobacteria,4D06G@85004|Bifidobacteriales 201174|Actinobacteria H ThiF family thiF - 2.7.7.73,2.7.7.80,2.8.1.11 ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF BHPHKHDA_00724 326426.Bbr_0694 1.19e-200 556.0 COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4CZ4A@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S thiG - 2.8.1.10 ko:K03149 ko00730,ko01100,map00730,map01100 - R10247 RC03096,RC03097,RC03461 ko00000,ko00001,ko01000 - - - ThiG,ThiS BHPHKHDA_00725 326426.Bbr_0693 5.91e-38 127.0 COG2104@1|root,COG2104@2|Bacteria,2GSKM@201174|Actinobacteria,4D1GS@85004|Bifidobacteriales 201174|Actinobacteria H ThiS family thiS - - ko:K03154 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS BHPHKHDA_00726 326426.Bbr_0692 0.0 965.0 COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CZ50@85004|Bifidobacteriales 201174|Actinobacteria E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0030312,GO:0040007,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 BHPHKHDA_00727 326426.Bbr_0688 1.2e-303 827.0 COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CZ2R@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0071944,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iNJ661.Rv1658 Arginosuc_synth BHPHKHDA_00728 326426.Bbr_0687 1.24e-109 316.0 COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4D0VM@85004|Bifidobacteriales 201174|Actinobacteria K Regulates arginine biosynthesis genes argR GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C BHPHKHDA_00729 326426.Bbr_0686 7.19e-234 643.0 COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CZGN@85004|Bifidobacteriales 201174|Actinobacteria E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0040007,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N BHPHKHDA_00730 326426.Bbr_0685 1.39e-314 856.0 COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,4CZGW@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-III argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0008150,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 BHPHKHDA_00731 326426.Bbr_0684 6.84e-226 622.0 COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CYYX@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase BHPHKHDA_00732 326426.Bbr_0683 9.26e-270 739.0 COG1364@1|root,COG1364@2|Bacteria,2GIW0@201174|Actinobacteria,4CZQQ@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ BHPHKHDA_00733 326426.Bbr_0682 5.47e-258 707.0 COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,4CZNC@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC BHPHKHDA_00734 326426.Bbr_0681 5.13e-137 389.0 2AHAX@1|root,317M8@2|Bacteria,2IPJ5@201174|Actinobacteria,4D11M@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00735 326426.Bbr_0680 0.0 1751.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CYUM@85004|Bifidobacteriales 201174|Actinobacteria J Phenylalanyl-tRNA synthetase beta pheT GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind BHPHKHDA_00736 326426.Bbr_0679 5.07e-257 705.0 COG0016@1|root,COG0016@2|Bacteria,2GJGG@201174|Actinobacteria,4CZ78@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d BHPHKHDA_00737 326426.Bbr_0678 8.12e-205 567.0 COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4CYZQ@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family tsnR - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind BHPHKHDA_00738 326426.Bbr_0677 1.45e-208 578.0 COG0619@1|root,COG0619@2|Bacteria,2IDC9@201174|Actinobacteria,4CZM8@85004|Bifidobacteriales 201174|Actinobacteria P Cobalt transport protein ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ BHPHKHDA_00739 326426.Bbr_0676 0.0 955.0 COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CYZ6@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities ykoD - - ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,CbiQ BHPHKHDA_00740 326426.Bbr_0675 4.38e-140 395.0 COG4721@1|root,COG4721@2|Bacteria,2IDAN@201174|Actinobacteria,4D00D@85004|Bifidobacteriales 201174|Actinobacteria S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt BHPHKHDA_00741 326426.Bbr_0674 0.0 896.0 COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CYZT@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase dimerisation domain argE - - - - - - - - - - - M20_dimer,Peptidase_M20 BHPHKHDA_00742 216816.GS08_03265 1.8e-129 369.0 2AN86@1|root,31D67@2|Bacteria,2HWWU@201174|Actinobacteria,4CZZS@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3043) - GO:0008150,GO:0009605,GO:0009607,GO:0020012,GO:0030682,GO:0042783,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - - - - - - - - - - DUF3043 BHPHKHDA_00743 326426.Bbr_0672 0.0 945.0 COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CZEI@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim BHPHKHDA_00744 326426.Bbr_0671 2.29e-179 500.0 2AUFS@1|root,2ZBYU@2|Bacteria,2I87Z@201174|Actinobacteria,4CYT8@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4191) - - - - - - - - - - - - DUF4191 BHPHKHDA_00745 326426.Bbr_0670 0.0 969.0 COG0174@1|root,COG0174@2|Bacteria,2GMN1@201174|Actinobacteria,4CZNK@85004|Bifidobacteriales 201174|Actinobacteria E glutamine synthetase glnA GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N BHPHKHDA_00746 326426.Bbr_0669 3.04e-259 711.0 COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2GJUZ@201174|Actinobacteria,4CZDC@85004|Bifidobacteriales 201174|Actinobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp GO:0008150,GO:0040007 - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA BHPHKHDA_00747 326426.Bbr_0668 0.0 1788.0 COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,4CZBC@85004|Bifidobacteriales 201174|Actinobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2 BHPHKHDA_00748 326426.Bbr_0667 0.0 2115.0 COG0457@1|root,COG0457@2|Bacteria,2GWSR@201174|Actinobacteria,4CZ33@85004|Bifidobacteriales 201174|Actinobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_19 BHPHKHDA_00749 326426.Bbr_0666 0.0 1417.0 COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CZXK@85004|Bifidobacteriales 201174|Actinobacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - BHPHKHDA_00750 1437608.BBIA_1626 3.54e-22 97.1 2A5FI@1|root,30U5H@2|Bacteria,2I8X3@201174|Actinobacteria,4D09F@85004|Bifidobacteriales 201174|Actinobacteria S Arylsulfotransferase Ig-like domain - - 2.8.2.22 ko:K01023 - - - - ko00000,ko01000 - - - Arylsulfotran_N,Arylsulfotrans BHPHKHDA_00751 326426.Bbr_0665 3.12e-179 500.0 COG1122@1|root,COG1122@2|Bacteria,2I9PF@201174|Actinobacteria,4D04S@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K16784 ko02010,map02010 M00581 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25.1 - - ABC_tran BHPHKHDA_00752 326426.Bbr_0664 2.74e-284 777.0 COG0436@1|root,COG0436@2|Bacteria,2GNMB@201174|Actinobacteria,4CZ48@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 BHPHKHDA_00753 326426.Bbr_0663 2.17e-243 670.0 COG0715@1|root,COG0715@2|Bacteria,2HZ9T@201174|Actinobacteria,4CZ56@85004|Bifidobacteriales 201174|Actinobacteria P NMT1/THI5 like - - - - - - - - - - - - NMT1 BHPHKHDA_00754 326426.Bbr_0662 8.22e-172 481.0 COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria,4CZ9Q@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 BHPHKHDA_00755 326426.Bbr_0661 1.58e-197 546.0 COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CZAR@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 - R06447,R09244,R09731 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf BHPHKHDA_00756 326426.Bbr_0660 4.62e-164 459.0 COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4CZCN@85004|Bifidobacteriales 201174|Actinobacteria L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N BHPHKHDA_00757 326426.Bbr_0659 0.0 1121.0 COG0657@1|root,COG0657@2|Bacteria,2I2GD@201174|Actinobacteria,4CZUD@85004|Bifidobacteriales 201174|Actinobacteria I acetylesterase activity - - - - - - - - - - - - - BHPHKHDA_00758 326426.Bbr_0658 6.58e-294 802.0 COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,4CYQB@85004|Bifidobacteriales 201174|Actinobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE BHPHKHDA_00759 326426.Bbr_0657 4.35e-282 771.0 COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4CZVC@85004|Bifidobacteriales 201174|Actinobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2870c DXPR_C,DXP_redisom_C,DXP_reductoisom BHPHKHDA_00760 326426.Bbr_0656 2.12e-295 816.0 COG3170@1|root,COG3170@2|Bacteria,2I2GE@201174|Actinobacteria,4CZDF@85004|Bifidobacteriales 201174|Actinobacteria NU Tfp pilus assembly protein FimV - - - - - - - - - - - - - BHPHKHDA_00762 326426.Bbr_0655 2.42e-96 280.0 2B57P@1|root,31Y1M@2|Bacteria,2IFRB@201174|Actinobacteria,4D307@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3052) - - - - - - - - - - - - DUF3052 BHPHKHDA_00763 326426.Bbr_0654 3.66e-211 585.0 COG3480@1|root,COG3480@2|Bacteria,2GMFX@201174|Actinobacteria,4CYUP@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the peptidase S16 family sdrC - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C BHPHKHDA_00764 326426.Bbr_0653 0.0 1072.0 COG5282@1|root,COG5282@2|Bacteria,2GJ9K@201174|Actinobacteria,4CYU7@85004|Bifidobacteriales 201174|Actinobacteria S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_2 BHPHKHDA_00765 326426.Bbr_0652 0.0 997.0 COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4CZ3A@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase uvrD2 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - HRDC,UvrD-helicase,UvrD_C BHPHKHDA_00766 326426.Bbr_0651 0.0 1036.0 COG3173@1|root,COG3173@2|Bacteria,2I8R6@201174|Actinobacteria,4CYPR@85004|Bifidobacteriales 201174|Actinobacteria S Aminoglycoside phosphotransferase mphA - - - - - - - - - - - APH BHPHKHDA_00767 326426.Bbr_0650 3.25e-44 143.0 2AS45@1|root,31HGW@2|Bacteria,2HZSD@201174|Actinobacteria,4D1H9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3107) - - - - - - - - - - - - DUF3107 BHPHKHDA_00768 326426.Bbr_0649 1.54e-216 597.0 COG0613@1|root,COG0613@2|Bacteria,2GNAP@201174|Actinobacteria,4CYQ5@85004|Bifidobacteriales 201174|Actinobacteria S DNA polymerase alpha chain like domain PPA1328 - 3.1.3.97,3.1.4.57 ko:K07053,ko:K20859 ko00440,map00440 - R00188,R10972,R10973,R11188 RC00078,RC00296 ko00000,ko00001,ko01000 - - - PHP BHPHKHDA_00769 326426.Bbr_0648 2.39e-166 465.0 COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,4CZN1@85004|Bifidobacteriales 201174|Actinobacteria S Vitamin K epoxide reductase - - - - - - - - - - - - VKOR BHPHKHDA_00770 326426.Bbr_0647 9.28e-219 603.0 COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,4CYQP@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase BHPHKHDA_00771 326426.Bbr_0646 4.68e-190 527.0 COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CZ54@85004|Bifidobacteriales 201174|Actinobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race BHPHKHDA_00772 326426.Bbr_0645 5.74e-204 564.0 COG4667@1|root,COG4667@2|Bacteria,2I8R7@201174|Actinobacteria,4CZUH@85004|Bifidobacteriales 201174|Actinobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin BHPHKHDA_00773 1437609.BCAL_1482 1.74e-72 230.0 COG1373@1|root,COG1373@2|Bacteria,2GM3Y@201174|Actinobacteria,4D05H@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_00774 326426.Bbr_0643 1.79e-170 481.0 COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CYTU@85004|Bifidobacteriales 201174|Actinobacteria O prohibitin homologues hflK GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - Band_7 BHPHKHDA_00775 1437608.BBIA_1356 1.41e-11 64.7 COG2873@1|root,COG2873@2|Bacteria,2I8JG@201174|Actinobacteria,4CZ6W@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme - - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP BHPHKHDA_00776 326426.Bbr_0642 3.8e-56 174.0 COG0695@1|root,COG0695@2|Bacteria,2HZQB@201174|Actinobacteria,4D18H@85004|Bifidobacteriales 201174|Actinobacteria O Glutaredoxin - - - - - - - - - - - - Glutaredoxin BHPHKHDA_00777 326426.Bbr_0641 1.83e-297 811.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CZKK@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metC1 - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP BHPHKHDA_00778 326426.Bbr_0640 1.2e-160 450.0 COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales 201174|Actinobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 BHPHKHDA_00779 326426.Bbr_0639 0.0 1456.0 COG0480@1|root,COG0480@2|Bacteria,2GJ64@201174|Actinobacteria,4CZM5@85004|Bifidobacteriales 201174|Actinobacteria J Elongation factor G, domain IV tetM - - ko:K18220 - - - - br01600,ko00000,ko01504 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU BHPHKHDA_00780 77635.BISU_0869 1.98e-06 53.9 2EHAX@1|root,33B2S@2|Bacteria,2HZMY@201174|Actinobacteria,4D0Z4@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00781 326426.Bbr_0637 7.2e-175 486.0 COG2176@1|root,COG2176@2|Bacteria,2I2FU@201174|Actinobacteria,4D10C@85004|Bifidobacteriales 201174|Actinobacteria L Exonuclease, DNA polymerase III, epsilon subunit family - - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - BRCT,RNase_T BHPHKHDA_00782 326426.Bbr_0636 2.64e-135 383.0 COG0194@1|root,COG0194@2|Bacteria,2I2FT@201174|Actinobacteria,4CYUT@85004|Bifidobacteriales 201174|Actinobacteria F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin BHPHKHDA_00783 326426.Bbr_0635 4.4e-216 597.0 COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4D2UX@85004|Bifidobacteriales 201174|Actinobacteria F Essential for recycling GMP and indirectly, cGMP pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase BHPHKHDA_00784 326426.Bbr_0634 0.0 2215.0 COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CZJ4@85004|Bifidobacteriales 201174|Actinobacteria EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS BHPHKHDA_00785 326426.Bbr_0633 2.95e-306 833.0 COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CYQ1@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the CarA family carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1383 CPSase_sm_chain,GATase BHPHKHDA_00786 326426.Bbr_0632 1.45e-120 344.0 COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4D0WG@85004|Bifidobacteriales 201174|Actinobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB GO:0008150,GO:0040007 - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB BHPHKHDA_00787 326426.Bbr_0631 6.57e-136 384.0 COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CYY6@85004|Bifidobacteriales 201174|Actinobacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C BHPHKHDA_00788 326426.Bbr_0630 1.23e-162 456.0 COG1136@1|root,COG1136@2|Bacteria,2I8QP@201174|Actinobacteria,4CZZG@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran BHPHKHDA_00789 326426.Bbr_0629 2.46e-175 490.0 COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,4CYRQ@85004|Bifidobacteriales 201174|Actinobacteria V Uncharacterised protein family (UPF0014) - - - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 BHPHKHDA_00790 326426.Bbr_0628 0.0 1537.0 COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4D0M7@85004|Bifidobacteriales 201174|Actinobacteria T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS,PAS_4,PAS_9 BHPHKHDA_00791 326426.Bbr_0627 0.0 880.0 COG3979@1|root,COG3979@2|Bacteria,2I2XD@201174|Actinobacteria,4CZW2@85004|Bifidobacteriales 201174|Actinobacteria S Carbohydrate binding domain - - 3.2.1.14 ko:K01183 ko00520,ko01100,map00520,map01100 - R01206,R02334 RC00467 ko00000,ko00001,ko01000 - GH18 - Glyco_hydro_18 BHPHKHDA_00792 326426.Bbr_0626 0.0 1448.0 COG1215@1|root,COG1215@2|Bacteria,2GN8M@201174|Actinobacteria,4D042@85004|Bifidobacteriales 201174|Actinobacteria M probably involved in cell wall - - - - - - - - - - - - EAL,Glyco_trans_2_3 BHPHKHDA_00794 326426.Bbr_0625 4.23e-63 192.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD,Cupin_2 BHPHKHDA_00795 326426.Bbr_0624 3.4e-236 652.0 COG0679@1|root,COG0679@2|Bacteria,2GMWC@201174|Actinobacteria,4D0CA@85004|Bifidobacteriales 201174|Actinobacteria S Membrane transport protein - - - ko:K07088 - - - - ko00000 - - - Mem_trans BHPHKHDA_00796 158787.BSCA_2014 2.75e-52 169.0 COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZYG@85004|Bifidobacteriales 201174|Actinobacteria S Maltose acetyltransferase - - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac BHPHKHDA_00797 326426.Bbr_0622 3.5e-149 421.0 COG0110@1|root,COG0110@2|Bacteria,2GNUB@201174|Actinobacteria,4CZ5H@85004|Bifidobacteriales 201174|Actinobacteria S Maltose acetyltransferase - - 2.3.1.18,2.3.1.79 ko:K00633,ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac BHPHKHDA_00798 1437608.BBIA_1406 0.000207 44.7 COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria,4D0NZ@85004|Bifidobacteriales 201174|Actinobacteria S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored BHPHKHDA_00799 326426.Bbr_0620 1.22e-156 440.0 COG2231@1|root,COG2231@2|Bacteria,2ICDU@201174|Actinobacteria,4D03Q@85004|Bifidobacteriales 201174|Actinobacteria L endonuclease III - - - ko:K07457 - - - - ko00000 - - - HhH-GPD BHPHKHDA_00800 326426.Bbr_0619 8.03e-311 848.0 COG0534@1|root,COG0534@2|Bacteria,2GXXK@201174|Actinobacteria,4CZU6@85004|Bifidobacteriales 201174|Actinobacteria V MatE - - - - - - - - - - - - MatE BHPHKHDA_00801 326426.Bbr_0618 0.0 1617.0 COG0178@1|root,COG0178@2|Bacteria,2GNMW@201174|Actinobacteria,4CZ5X@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA3 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran BHPHKHDA_00802 158787.BSCA_1968 1.33e-176 495.0 COG0583@1|root,COG0583@2|Bacteria,2GK13@201174|Actinobacteria,4CZKC@85004|Bifidobacteriales 201174|Actinobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate BHPHKHDA_00803 1437610.BREU_1105 6.97e-253 702.0 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_00804 1437609.BCAL_0114 2.56e-197 549.0 COG0583@1|root,COG0583@2|Bacteria,2HZHV@201174|Actinobacteria,4D0HN@85004|Bifidobacteriales 201174|Actinobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate BHPHKHDA_00805 1437610.BREU_0131 9.67e-274 751.0 COG2942@1|root,COG2942@2|Bacteria,2GMJ7@201174|Actinobacteria,4CZNY@85004|Bifidobacteriales 201174|Actinobacteria G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) - - - - - - - - - - - - GlcNAc_2-epim BHPHKHDA_00807 1122228.AQXR01000009_gene1308 1.5e-180 510.0 COG1609@1|root,COG1609@2|Bacteria,2GJHF@201174|Actinobacteria,4CZCC@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_00808 1437609.BCAL_0292 0.0 1458.0 COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria,4D09M@85004|Bifidobacteriales 201174|Actinobacteria G beta-mannosidase - - 3.2.1.25 ko:K01192 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Glyco_hydro_2 BHPHKHDA_00809 1437609.BCAL_0291 4.88e-176 493.0 COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4CYW7@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY BHPHKHDA_00810 78344.BIGA_1562 2.96e-173 500.0 COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,2GIXV@201174|Actinobacteria,4D0C4@85004|Bifidobacteriales 201174|Actinobacteria EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,BPD_transp_1,oligo_HPY BHPHKHDA_00811 1437609.BCAL_0289 3.01e-197 552.0 COG1173@1|root,COG1173@2|Bacteria,2I2WP@201174|Actinobacteria,4D2RU@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 BHPHKHDA_00812 1437609.BCAL_0288 1.79e-222 615.0 COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,4D009@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 BHPHKHDA_00813 1437609.BCAL_0287 0.0 1045.0 COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4D0JU@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 BHPHKHDA_00814 1437609.BCAL_0286 1.06e-297 816.0 COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4CYPX@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 1 bglA - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 BHPHKHDA_00815 78344.BIGA_1557 6.01e-186 525.0 COG2755@1|root,COG2755@2|Bacteria,2H9RY@201174|Actinobacteria,4D06T@85004|Bifidobacteriales 201174|Actinobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2,RicinB_lectin_2 BHPHKHDA_00816 158787.BSCA_0131 8.35e-212 612.0 COG2755@1|root,COG2755@2|Bacteria,2I2FJ@201174|Actinobacteria,4D2US@85004|Bifidobacteriales 201174|Actinobacteria E Carbohydrate esterase, sialic acid-specific acetylesterase - - 3.1.1.53 ko:K05970 - - - - ko00000,ko01000 - - - SASA BHPHKHDA_00817 158787.BSCA_1988 2.38e-99 292.0 COG0745@1|root,COG0745@2|Bacteria,2IBSR@201174|Actinobacteria,4CZUS@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C BHPHKHDA_00818 158787.BSCA_1989 1.52e-45 152.0 28PR5@1|root,2ZCD3@2|Bacteria,2IT27@201174|Actinobacteria,4D19Z@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00819 158787.BSCA_1993 0.0 875.0 COG1373@1|root,COG1373@2|Bacteria,2GM3Y@201174|Actinobacteria,4D05H@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_00820 326426.Bbr_0615 5.61e-251 688.0 COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4CZJY@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase adh - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N BHPHKHDA_00821 326426.Bbr_0614 1.06e-97 286.0 COG0789@1|root,COG0789@2|Bacteria,2HZK3@201174|Actinobacteria,4D0RM@85004|Bifidobacteriales 201174|Actinobacteria K MerR family regulatory protein - - - - - - - - - - - - MerR,MerR_1 BHPHKHDA_00822 326426.Bbr_0613 2.12e-114 329.0 COG0239@1|root,COG0239@2|Bacteria,2IJGQ@201174|Actinobacteria,4D11I@85004|Bifidobacteriales 201174|Actinobacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity - - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB BHPHKHDA_00823 326426.Bbr_0612 1.37e-78 234.0 COG0239@1|root,COG0239@2|Bacteria,2IC26@201174|Actinobacteria,4D14T@85004|Bifidobacteriales 201174|Actinobacteria U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB BHPHKHDA_00824 158787.BSCA_2006 2.16e-40 137.0 COG2246@1|root,COG2246@2|Bacteria,2II4Y@201174|Actinobacteria,4D0YG@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - GtrA BHPHKHDA_00826 326426.Bbr_0610 1.02e-236 653.0 COG2855@1|root,COG2855@2|Bacteria,2GS6E@201174|Actinobacteria,4CZWB@85004|Bifidobacteriales 201174|Actinobacteria S Conserved hypothetical protein 698 - - - - - - - - - - - - Cons_hypoth698 BHPHKHDA_00827 326426.Bbr_0609 4.28e-185 515.0 COG0583@1|root,COG0583@2|Bacteria,2HZCS@201174|Actinobacteria,4CZT1@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate BHPHKHDA_00828 326426.Bbr_0608 1.04e-164 461.0 28XY7@1|root,2ZJU4@2|Bacteria,2GN31@201174|Actinobacteria,4CZQG@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4391) tmp1 - - - - - - - - - - - DUF4391 BHPHKHDA_00829 326426.Bbr_0607 4.1e-293 799.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 201174|Actinobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 BHPHKHDA_00830 326426.Bbr_0606 0.0 1404.0 COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CYTB@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 BHPHKHDA_00831 1437610.BREU_2069 1.9e-104 302.0 COG0049@1|root,COG0049@2|Bacteria,2GMVW@201174|Actinobacteria,4CZQJ@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 BHPHKHDA_00832 1437608.BBIA_0395 5.77e-81 240.0 COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4D0PK@85004|Bifidobacteriales 201174|Actinobacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 BHPHKHDA_00833 326426.Bbr_0603 3.25e-142 408.0 COG0385@1|root,COG0385@2|Bacteria,2GMAM@201174|Actinobacteria,4CZ1K@85004|Bifidobacteriales 201174|Actinobacteria S SBF-like CPA transporter family (DUF4137) - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF BHPHKHDA_00835 326426.Bbr_0602 1.01e-250 687.0 COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4CZ7G@85004|Bifidobacteriales 201174|Actinobacteria E Beta-eliminating lyase ltaE - 4.1.2.48 ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 - R00751,R06171 RC00312,RC00372 ko00000,ko00001,ko01000 - - - Beta_elim_lyase BHPHKHDA_00836 326426.Bbr_0601 6.11e-277 757.0 COG0438@1|root,COG0438@2|Bacteria,2HEH6@201174|Actinobacteria,4CZSN@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 BHPHKHDA_00837 326426.Bbr_0600 1.56e-110 328.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZCF@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II - - 2.6.1.1,2.6.1.2,2.6.1.66,2.6.1.83 ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034,M00527 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396,R07613 RC00006,RC00008,RC00036,RC01847 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 BHPHKHDA_00838 547043.BIFPSEUDO_03278 3.76e-57 184.0 COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZQK@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_Tnp_1,rve,rve_3 BHPHKHDA_00839 1680.BADO_0645 2.09e-18 84.0 COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria,4CZRU@85004|Bifidobacteriales 201174|Actinobacteria P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoA,FeoB_C,FeoB_N,Gate BHPHKHDA_00840 566552.BIFCAT_01933 4.64e-165 471.0 COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4CZ65@85004|Bifidobacteriales 201174|Actinobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE BHPHKHDA_00841 326426.Bbr_0857 2.78e-82 243.0 COG0346@1|root,COG0346@2|Bacteria,2II51@201174|Actinobacteria,4D0V7@85004|Bifidobacteriales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gloA - - - - - - - - - - - Glyoxalase BHPHKHDA_00843 326426.Bbr_0859 4.76e-305 834.0 COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4D02G@85004|Bifidobacteriales 201174|Actinobacteria EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 BHPHKHDA_00844 326426.Bbr_0860 4.41e-137 387.0 COG0560@1|root,COG0560@2|Bacteria,2GMVR@201174|Actinobacteria,4D0CF@85004|Bifidobacteriales 201174|Actinobacteria E haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD BHPHKHDA_00845 216816.GS08_04295 5.13e-209 576.0 COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria,4CZFM@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 BHPHKHDA_00846 326426.Bbr_0862 4.87e-298 814.0 COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZR8@85004|Bifidobacteriales 201174|Actinobacteria F Permease family rutG - - ko:K02824,ko:K03458 - - - - ko00000,ko02000 2.A.40,2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease BHPHKHDA_00847 326426.Bbr_0863 0.0 1197.0 COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CZ4K@85004|Bifidobacteriales 201174|Actinobacteria JKL helicase superfamily c-terminal domain - - - - - - - - - - - - DEAD,Helicase_C BHPHKHDA_00848 326426.Bbr_0864 0.0 877.0 COG0366@1|root,COG0366@2|Bacteria,2GJUT@201174|Actinobacteria,4D075@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain nplT - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459 BHPHKHDA_00849 326426.Bbr_0865 1.78e-241 665.0 COG0306@1|root,COG0306@2|Bacteria,2GJHK@201174|Actinobacteria,4CZM7@85004|Bifidobacteriales 201174|Actinobacteria P Phosphate transporter family pitB GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K03306 - - - - ko00000 2.A.20 - iNJ661.Rv2281 PHO4 BHPHKHDA_00850 326426.Bbr_0866 7.51e-145 408.0 COG1392@1|root,COG1392@2|Bacteria,2HNQ5@201174|Actinobacteria,4CZVQ@85004|Bifidobacteriales 201174|Actinobacteria P Protein of unknown function DUF47 - - - ko:K07220 - - - - ko00000 - - - PhoU_div BHPHKHDA_00851 326426.Bbr_0867 1.38e-145 411.0 COG2197@1|root,COG2197@2|Bacteria,2IBZ9@201174|Actinobacteria,4D07J@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg BHPHKHDA_00852 216816.GS08_04335 4.53e-274 755.0 COG4585@1|root,COG4585@2|Bacteria,2I9G4@201174|Actinobacteria,4CZHY@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 BHPHKHDA_00853 158787.BSCA_2234 1.01e-13 69.7 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4D20B@85004|Bifidobacteriales 201174|Actinobacteria P Cation transporter/ATPase, N-terminus - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 BHPHKHDA_00854 326426.Bbr_0870 6.27e-224 618.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CYUQ@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 BHPHKHDA_00855 398513.BBNG_00716 5.48e-281 770.0 COG0842@1|root,COG0842@2|Bacteria,2IBJP@201174|Actinobacteria,4CZD5@85004|Bifidobacteriales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 BHPHKHDA_00856 398513.BBNG_00717 2.84e-304 834.0 COG0842@1|root,COG0842@2|Bacteria,2H9HW@201174|Actinobacteria,4CZ1J@85004|Bifidobacteriales 201174|Actinobacteria V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 BHPHKHDA_00857 398513.BBNG_00718 0.0 971.0 COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales 201174|Actinobacteria K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,HTH_24,HTH_5 BHPHKHDA_00858 216816.GS08_04380 2.69e-62 193.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - GAF,Lipase_GDSL_2 BHPHKHDA_00859 326426.Bbr_0875 6.11e-262 721.0 2CGVZ@1|root,33209@2|Bacteria,2IEU5@201174|Actinobacteria,4CZAJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00860 326426.Bbr_0876 4.17e-142 401.0 COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria,4D10R@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family S51 pepE GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 ko:K05995 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S51 BHPHKHDA_00861 326426.Bbr_0877 2.51e-137 389.0 COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,4CYTT@85004|Bifidobacteriales 201174|Actinobacteria Q Isochorismatase family pncA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase BHPHKHDA_00862 326426.Bbr_0878 3.78e-219 605.0 COG0791@1|root,COG0791@2|Bacteria,2I38D@201174|Actinobacteria,4D2XJ@85004|Bifidobacteriales 201174|Actinobacteria M pfam nlp p60 - - - - - - - - - - - - - BHPHKHDA_00863 326426.Bbr_0879 3.68e-195 541.0 COG2267@1|root,COG2267@2|Bacteria,2GNRY@201174|Actinobacteria,4D02B@85004|Bifidobacteriales 201174|Actinobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 BHPHKHDA_00864 158787.BSCA_2474 4.02e-58 187.0 2B2KB@1|root,31V5N@2|Bacteria,2GV1B@201174|Actinobacteria,4D1EE@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF2975) - - - - - - - - - - - - DUF2975 BHPHKHDA_00865 326426.Bbr_0882 2.88e-307 840.0 COG2233@1|root,COG2233@2|Bacteria,2GMH6@201174|Actinobacteria,4CZ9F@85004|Bifidobacteriales 201174|Actinobacteria F Permease family pbuX - - ko:K03458 - - - - ko00000 2.A.40 - - Xan_ur_permease BHPHKHDA_00866 326426.Bbr_0883 1.48e-135 384.0 COG0503@1|root,COG0503@2|Bacteria,2GJ3S@201174|Actinobacteria,4CYSZ@85004|Bifidobacteriales 201174|Actinobacteria F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran BHPHKHDA_00867 326426.Bbr_0884 0.0 1584.0 COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CYRJ@85004|Bifidobacteriales 201174|Actinobacteria L DNA helicase pcrA GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C BHPHKHDA_00868 326426.Bbr_0885 4.61e-84 248.0 2CBVU@1|root,3324G@2|Bacteria,2IKKE@201174|Actinobacteria,4D106@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4418) - - - - - - - - - - - - DUF4418 BHPHKHDA_00869 326426.Bbr_0886 1.28e-274 753.0 COG0577@1|root,COG0577@2|Bacteria,2H8C2@201174|Actinobacteria,4CZB5@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BHPHKHDA_00870 326426.Bbr_0887 3.15e-203 564.0 COG1136@1|root,COG1136@2|Bacteria,2IATV@201174|Actinobacteria,4CZMH@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00871 326426.Bbr_0888 5.26e-141 399.0 COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,4CYSP@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 BHPHKHDA_00872 326426.Bbr_0889 1.07e-193 536.0 COG2071@1|root,COG2071@2|Bacteria,2GIV6@201174|Actinobacteria,4D043@85004|Bifidobacteriales 201174|Actinobacteria S Peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 BHPHKHDA_00873 326426.Bbr_0890 1.54e-90 266.0 COG0295@1|root,COG0295@2|Bacteria,2IMXP@201174|Actinobacteria,4D1XM@85004|Bifidobacteriales 201174|Actinobacteria F cytidine deaminase activity - - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 BHPHKHDA_00874 326426.Bbr_0891 1.01e-65 201.0 COG5658@1|root,COG5658@2|Bacteria,2GWJG@201174|Actinobacteria,4D1RC@85004|Bifidobacteriales 201174|Actinobacteria S SdpI/YhfL protein family - - - - - - - - - - - - SdpI BHPHKHDA_00875 216816.GS08_04475 1.03e-143 405.0 COG1305@1|root,COG1305@2|Bacteria,2GM42@201174|Actinobacteria,4D0N1@85004|Bifidobacteriales 201174|Actinobacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core BHPHKHDA_00876 216816.GS08_04480 6.1e-85 249.0 COG2337@1|root,COG2337@2|Bacteria,2GZTW@201174|Actinobacteria,4D25G@85004|Bifidobacteriales 201174|Actinobacteria T PemK-like, MazF-like toxin of type II toxin-antitoxin system - - - - - - - - - - - - PemK_toxin BHPHKHDA_00877 326426.Bbr_0894 2.55e-65 198.0 COG3077@1|root,COG3077@2|Bacteria,2GRAY@201174|Actinobacteria,4D1J9@85004|Bifidobacteriales 201174|Actinobacteria L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB BHPHKHDA_00878 326426.Bbr_0895 2.43e-166 464.0 COG0406@1|root,COG0406@2|Bacteria,2GK2I@201174|Actinobacteria,4CZH2@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 BHPHKHDA_00879 326426.Bbr_0896 1.28e-76 229.0 COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4D0VH@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF948) - - - - - - - - - - - - DUF948 BHPHKHDA_00880 326426.Bbr_0897 6.59e-48 153.0 2B9VR@1|root,3238X@2|Bacteria,2IQYT@201174|Actinobacteria,4D16I@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00881 326426.Bbr_0898 0.0 1754.0 COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,4CZQN@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD BHPHKHDA_00882 326426.Bbr_0899 2.12e-99 289.0 COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,4D0WQ@85004|Bifidobacteriales 201174|Actinobacteria L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA ruvX GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX BHPHKHDA_00883 326426.Bbr_0900 2.97e-252 696.0 COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4CZID@85004|Bifidobacteriales 201174|Actinobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG BHPHKHDA_00884 216816.GS08_04525 1.74e-91 269.0 2B59B@1|root,31Y3G@2|Bacteria,2GRM1@201174|Actinobacteria,4D110@85004|Bifidobacteriales 201174|Actinobacteria S Type IV leader peptidase family - - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - Peptidase_A24 BHPHKHDA_00885 326426.Bbr_0902 1.01e-275 755.0 COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CZ43@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2540c Chorismate_synt BHPHKHDA_00886 326426.Bbr_0903 0.0 1075.0 COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2GIUZ@201174|Actinobacteria,4CZ2G@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI BHPHKHDA_00887 326426.Bbr_0904 2.01e-102 296.0 COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4D0Q6@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ GO:0003674,GO:0003824,GO:0003855,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II BHPHKHDA_00888 216816.GS08_04710 1.24e-120 353.0 COG5340@1|root,COG5340@2|Bacteria,2IDUY@201174|Actinobacteria,4D00E@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - - BHPHKHDA_00889 641146.HMPREF9020_01339 4.21e-31 116.0 COG0582@1|root,COG4974@1|root,COG0582@2|Bacteria,COG4974@2|Bacteria,2IH6A@201174|Actinobacteria,4CZ62@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase BHPHKHDA_00891 326426.Bbr_1122 0.0 1257.0 COG0550@1|root,COG0550@2|Bacteria,2GJU7@201174|Actinobacteria,4D044@85004|Bifidobacteriales 201174|Actinobacteria L DNA topoisomerase - - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt BHPHKHDA_00892 326426.Bbr_1121 1.2e-262 718.0 COG0270@1|root,COG0270@2|Bacteria,2GJR6@201174|Actinobacteria 201174|Actinobacteria H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family - - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase BHPHKHDA_00893 326426.Bbr_1120 0.0 1347.0 COG0323@1|root,COG0323@2|Bacteria,2IATP@201174|Actinobacteria 201174|Actinobacteria L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c_3 BHPHKHDA_00894 326426.Bbr_1119 0.0 923.0 COG0827@1|root,COG0827@2|Bacteria,2IA5K@201174|Actinobacteria,4CZQ7@85004|Bifidobacteriales 201174|Actinobacteria L Eco57I restriction-modification methylase - - 2.1.1.72 ko:K07317 - - - - ko00000,ko01000,ko02048 - - - Eco57I,MTS,N6_Mtase,PCMT,RrnaAD BHPHKHDA_00895 326426.Bbr_1118 3.7e-233 640.0 COG0827@1|root,COG0827@2|Bacteria,2IA07@201174|Actinobacteria,4CZ6Z@85004|Bifidobacteriales 201174|Actinobacteria L BsuBI/PstI restriction endonuclease C-terminus - - 3.1.21.4 ko:K01155 - - - - ko00000,ko01000,ko02048 - - - BsuBI_PstI_RE BHPHKHDA_00896 702459.BBPR_0018 9.61e-287 784.0 2DB8S@1|root,2Z7SU@2|Bacteria,2IC6Z@201174|Actinobacteria,4D099@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - zinc_ribbon_2 BHPHKHDA_00898 702459.BBPR_0019 6.83e-89 268.0 COG4974@1|root,COG4974@2|Bacteria,2IH6A@201174|Actinobacteria,4CZ62@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase BHPHKHDA_00899 702459.BBPR_0019 5.25e-107 314.0 COG4974@1|root,COG4974@2|Bacteria,2IH6A@201174|Actinobacteria,4CZ62@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase BHPHKHDA_00900 326426.Bbr_1112 9.48e-47 154.0 COG0739@1|root,COG0739@2|Bacteria,2IQ64@201174|Actinobacteria,4D199@85004|Bifidobacteriales 201174|Actinobacteria M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 BHPHKHDA_00901 326426.Bbr_1111 0.0 943.0 COG4213@1|root,COG4213@2|Bacteria,2HZAK@201174|Actinobacteria,4CZCR@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter substrate-binding protein - - - - - - - - - - - - Peripla_BP_4 BHPHKHDA_00902 326426.Bbr_1110 9.53e-307 834.0 COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4CZ8V@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the isocitrate and isopropylmalate dehydrogenases family icd GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh BHPHKHDA_00903 326426.Bbr_1109 4.18e-262 719.0 COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CZDK@85004|Bifidobacteriales 201174|Actinobacteria F IMP dehydrogenase family protein guaB3 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - IMPDH BHPHKHDA_00904 326426.Bbr_1108 5.83e-120 342.0 2BGJW@1|root,32AI7@2|Bacteria,2IR97@201174|Actinobacteria,4D19G@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00905 326426.Bbr_1107 0.0 1271.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYVD@85004|Bifidobacteriales 201174|Actinobacteria I long-chain-fatty acid CoA ligase fadD3 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding BHPHKHDA_00906 326426.Bbr_1106 1.96e-113 325.0 COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,4CZ63@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase BHPHKHDA_00907 326426.Bbr_1105 1.56e-191 532.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 BHPHKHDA_00908 326426.Bbr_1104 3.6e-183 511.0 COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CYVQ@85004|Bifidobacteriales 201174|Actinobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS BHPHKHDA_00909 326426.Bbr_1103 1.09e-170 477.0 COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,4CZEK@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase BHPHKHDA_00910 326426.Bbr_1102 7.06e-120 343.0 COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CYTF@85004|Bifidobacteriales 201174|Actinobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF BHPHKHDA_00911 326426.Bbr_1101 6.76e-222 613.0 COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,4CYZM@85004|Bifidobacteriales 201174|Actinobacteria I Cytidylyltransferase family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 BHPHKHDA_00912 326426.Bbr_1100 1.85e-284 776.0 COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CZG2@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM BHPHKHDA_00913 216816.GS08_05710 7.48e-68 208.0 COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4D0H3@85004|Bifidobacteriales 201174|Actinobacteria S DJ-1/PfpI family - - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI BHPHKHDA_00914 1437610.BREU_1111 4.75e-21 87.4 COG0693@1|root,COG0693@2|Bacteria,2GMMW@201174|Actinobacteria,4D0H3@85004|Bifidobacteriales 201174|Actinobacteria S DJ-1/PfpI family - - 3.5.1.124 ko:K05520 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI BHPHKHDA_00915 326426.Bbr_1098 1.18e-179 500.0 COG0107@1|root,COG0107@2|Bacteria,2GIRP@201174|Actinobacteria,4CZ8Z@85004|Bifidobacteriales 201174|Actinobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023,M00026 R00985,R00986,R04558 RC00010,RC01190,RC01943,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth BHPHKHDA_00916 326426.Bbr_1097 1.32e-92 270.0 COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4D0WW@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI GO:0008150,GO:0040007 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1606 PRA-CH BHPHKHDA_00917 326426.Bbr_1096 0.0 1025.0 COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,4CZHW@85004|Bifidobacteriales 201174|Actinobacteria E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind BHPHKHDA_00918 1437608.BBIA_0681 5.46e-118 340.0 COG3738@1|root,COG3738@2|Bacteria,2IBMJ@201174|Actinobacteria,4CZM2@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF1287) - - - ko:K09974 - - - - ko00000 - - - DUF1287 BHPHKHDA_00919 326426.Bbr_1094 3.58e-206 574.0 COG2865@1|root,COG2865@2|Bacteria,2IF0U@201174|Actinobacteria,4D0I9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00920 326426.Bbr_1093 2.3e-96 280.0 2ATA8@1|root,31IT9@2|Bacteria,2IICV@201174|Actinobacteria,4D0W4@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00921 326426.Bbr_1092 5.5e-84 249.0 COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales 201174|Actinobacteria K Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 BHPHKHDA_00922 326426.Bbr_1091 5.32e-11 60.1 2B5AB@1|root,31YAH@2|Bacteria,2HZT2@201174|Actinobacteria,4D1NJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00923 326426.Bbr_1090 0.0 1020.0 COG0833@1|root,COG0833@2|Bacteria,2I2DX@201174|Actinobacteria,4D2V7@85004|Bifidobacteriales 201174|Actinobacteria E amino acid - - - ko:K16235 - - - - ko00000,ko02000 2.A.3.1.10 - - AA_permease BHPHKHDA_00924 1122238.AULR01000004_gene2511 1.77e-27 102.0 COG2211@1|root,COG2211@2|Bacteria 2|Bacteria G Major facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_00925 216816.GS08_05075 2.68e-54 176.0 COG0477@1|root,COG0477@2|Bacteria,2I2GG@201174|Actinobacteria,4D2V3@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_00926 762211.BSTEL_0362 8.55e-120 353.0 COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CYZ2@85004|Bifidobacteriales 201174|Actinobacteria U Membrane protein insertase, YidC Oxa1 family yidC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP BHPHKHDA_00927 216816.GS08_05100 2.25e-150 422.0 COG1051@1|root,COG1051@2|Bacteria,2I0XY@201174|Actinobacteria,4D08F@85004|Bifidobacteriales 201174|Actinobacteria F Hydrolase of X-linked nucleoside diphosphate N terminal - - - - - - - - - - - - NUDIX,Nudix_N BHPHKHDA_00928 216816.GS08_05105 7.15e-43 140.0 COG0388@1|root,COG0388@2|Bacteria,2I009@201174|Actinobacteria,4D2GR@85004|Bifidobacteriales 201174|Actinobacteria S Carbon-nitrogen hydrolase - - - - - - - - - - - - CN_hydrolase BHPHKHDA_00929 216816.GS08_05120 4.3e-120 345.0 2BNX6@1|root,32HM5@2|Bacteria,2GQ6P@201174|Actinobacteria,4D027@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00932 326426.Bbr_1078 3.17e-156 438.0 COG1131@1|root,COG1131@2|Bacteria,2IEJK@201174|Actinobacteria,4D0K4@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_00933 326426.Bbr_1077 2.58e-167 468.0 2EXFX@1|root,33QS8@2|Bacteria,2IC7Z@201174|Actinobacteria,4CZUQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00934 216816.GS08_05145 8.32e-133 378.0 2F10A@1|root,33U1T@2|Bacteria,2IAKS@201174|Actinobacteria,4D01S@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_00935 216816.GS08_05150 4.12e-178 499.0 COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4D03A@85004|Bifidobacteriales 201174|Actinobacteria S EamA-like transporter family - - - ko:K11939 - - - - ko00000,ko02000 2.A.7.3.6 - - EamA BHPHKHDA_00936 326426.Bbr_1085 1.68e-51 165.0 2DZQA@1|root,32VG4@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - BHPHKHDA_00937 326426.Bbr_1084 8.76e-63 192.0 COG3877@1|root,COG3877@2|Bacteria,2INCH@201174|Actinobacteria,4D10P@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 BHPHKHDA_00938 398513.BBNG_01020 8.31e-115 332.0 COG1670@1|root,COG1670@2|Bacteria,2HZBU@201174|Actinobacteria,4CZN2@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 BHPHKHDA_00939 1437608.BBIA_0727 1.64e-119 346.0 COG2197@1|root,COG2197@2|Bacteria,2HRPE@201174|Actinobacteria,4D098@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg BHPHKHDA_00940 1437608.BBIA_1582 4.54e-83 259.0 COG4585@1|root,COG4585@2|Bacteria,2IJ42@201174|Actinobacteria,4D13Z@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - 2.7.13.3 ko:K07675 ko02020,map02020 M00473 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HisKA_3 BHPHKHDA_00941 1437608.BBIA_0730 7.78e-71 214.0 COG5658@1|root,COG5658@2|Bacteria,2GWJG@201174|Actinobacteria,4D1RC@85004|Bifidobacteriales 201174|Actinobacteria S SdpI/YhfL protein family - - - - - - - - - - - - SdpI BHPHKHDA_00942 857290.HMPREF9156_01212 6.37e-125 364.0 COG2746@1|root,COG2746@2|Bacteria,2GNV9@201174|Actinobacteria,4D1K3@85004|Bifidobacteriales 201174|Actinobacteria V Aminoglycoside 3-N-acetyltransferase - - 2.3.1.81 ko:K00662 - - - - ko00000,ko01000,ko01504 - - - Antibiotic_NAT BHPHKHDA_00943 326426.Bbr_1614 2.36e-90 268.0 COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4D0PZ@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 BHPHKHDA_00944 326426.Bbr_1615 8.1e-236 649.0 COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CZEN@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L BHPHKHDA_00945 216816.GS08_08970 7.34e-86 253.0 COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4D0PJ@85004|Bifidobacteriales 201174|Actinobacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 BHPHKHDA_00946 326426.Bbr_1617 2e-82 244.0 COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4D0PQ@85004|Bifidobacteriales 201174|Actinobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 BHPHKHDA_00947 158787.BSCA_1163 1.47e-20 81.3 COG0257@1|root,COG0257@2|Bacteria,2GWMH@201174|Actinobacteria,4D1NT@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 BHPHKHDA_00948 1435051.BMOU_1728 6.91e-45 145.0 COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria,4D16H@85004|Bifidobacteriales 201174|Actinobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA - - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a BHPHKHDA_00949 326426.Bbr_1620 1.05e-127 363.0 COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CZ7Z@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid BHPHKHDA_00950 216816.GS08_08995 5.04e-315 858.0 COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CYWU@85004|Bifidobacteriales 201174|Actinobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY BHPHKHDA_00951 326426.Bbr_1622 1.07e-98 287.0 COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4D0R9@85004|Bifidobacteriales 201174|Actinobacteria J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A BHPHKHDA_00952 216816.GS08_09005 4.64e-36 122.0 COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4D1EZ@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L30p/L7e rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 BHPHKHDA_00953 326426.Bbr_1624 2.25e-129 372.0 COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CZCD@85004|Bifidobacteriales 201174|Actinobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C BHPHKHDA_00954 326426.Bbr_1625 3.09e-76 228.0 COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D0WE@85004|Bifidobacteriales 201174|Actinobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p BHPHKHDA_00955 326426.Bbr_1626 5.43e-122 348.0 COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4CYQV@85004|Bifidobacteriales 201174|Actinobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 BHPHKHDA_00956 1437610.BREU_0623 3.17e-90 264.0 COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,4D0P6@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 BHPHKHDA_00957 1437609.BCAL_1317 7.06e-40 131.0 COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4D177@85004|Bifidobacteriales 201174|Actinobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 BHPHKHDA_00958 326426.Bbr_1629 3.93e-134 380.0 COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CZCA@85004|Bifidobacteriales 201174|Actinobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C BHPHKHDA_00959 326426.Bbr_1630 5.4e-69 209.0 COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4D10I@85004|Bifidobacteriales 201174|Actinobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 BHPHKHDA_00960 216816.GS08_09045 2.55e-79 236.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4D0VI@85004|Bifidobacteriales 201174|Actinobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 BHPHKHDA_00961 216816.GS08_09050 1.11e-54 171.0 COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria,4D10N@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 BHPHKHDA_00962 216816.GS08_09055 1.97e-49 157.0 COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4D181@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 BHPHKHDA_00963 326426.Bbr_1634 3.85e-98 285.0 COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,4D0Q8@85004|Bifidobacteriales 201174|Actinobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 BHPHKHDA_00964 326426.Bbr_1635 1.85e-156 442.0 COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,4CYQN@85004|Bifidobacteriales 201174|Actinobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C BHPHKHDA_00965 326426.Bbr_1636 1.09e-74 224.0 COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4D0UZ@85004|Bifidobacteriales 201174|Actinobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 BHPHKHDA_00966 1437608.BBIA_2303 1.4e-62 191.0 COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4D105@85004|Bifidobacteriales 201174|Actinobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 BHPHKHDA_00967 326426.Bbr_1638 3.85e-195 541.0 COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CZ5U@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C BHPHKHDA_00968 326426.Bbr_1639 2.54e-61 188.0 COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4D11N@85004|Bifidobacteriales 201174|Actinobacteria J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 BHPHKHDA_00969 326426.Bbr_1640 9.78e-151 424.0 COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,4CZSA@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 BHPHKHDA_00970 326426.Bbr_1641 1.11e-149 421.0 COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CYQD@85004|Bifidobacteriales 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 BHPHKHDA_00971 1437600.JDUI01000009_gene364 9.35e-68 205.0 COG0051@1|root,COG0051@2|Bacteria,2IHRA@201174|Actinobacteria,4D0UT@85004|Bifidobacteriales 201174|Actinobacteria J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 BHPHKHDA_00972 216816.GS08_09105 3.82e-176 491.0 COG3527@1|root,COG3527@2|Bacteria,2IBRH@201174|Actinobacteria,4D0BN@85004|Bifidobacteriales 201174|Actinobacteria H Alpha-acetolactate decarboxylase budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy BHPHKHDA_00973 326426.Bbr_1644 7.26e-185 516.0 28NT3@1|root,2ZBRV@2|Bacteria,2IIC3@201174|Actinobacteria,4D0MQ@85004|Bifidobacteriales 201174|Actinobacteria S YwiC-like protein - - - - - - - - - - - - YwiC BHPHKHDA_00974 326426.Bbr_1645 0.0 1747.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 201174|Actinobacteria C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10,1.2.1.81 ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH BHPHKHDA_00975 78345.BMERY_0610 2.64e-217 600.0 COG2207@1|root,COG2207@2|Bacteria,2HZE7@201174|Actinobacteria,4D00U@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18 BHPHKHDA_00976 78345.BMERY_0609 6.49e-245 673.0 COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4D04X@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.1.1.9 ko:K05351 ko00040,ko01100,map00040,map01100 M00014 R01896 RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N BHPHKHDA_00977 547043.BIFPSEUDO_02633 1.73e-248 690.0 COG0477@1|root,COG2814@2|Bacteria,2GPRH@201174|Actinobacteria,4D048@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily csbX - - - - - - - - - - - MFS_1 BHPHKHDA_00978 78345.BMERY_0607 2.69e-272 745.0 COG1940@1|root,COG1940@2|Bacteria,2I7R8@201174|Actinobacteria,4CZZ7@85004|Bifidobacteriales 201174|Actinobacteria GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565 - - - - - - - - - - - - HTH_24,MarR,ROK BHPHKHDA_00979 78345.BMERY_0606 2.66e-97 282.0 COG0346@1|root,COG0346@2|Bacteria,2IHBC@201174|Actinobacteria,4D0P3@85004|Bifidobacteriales 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase BHPHKHDA_00980 78346.BRUM_0709 3.04e-296 812.0 COG0477@1|root,COG2814@2|Bacteria,2GPRH@201174|Actinobacteria,4D048@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily csbX - - - - - - - - - - - MFS_1 BHPHKHDA_00981 78345.BMERY_0604 2.47e-227 627.0 COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4D04X@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase - - 1.1.1.1,1.1.1.287,1.6.5.5 ko:K00001,ko:K00344,ko:K17818 ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R07143,R07144,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N BHPHKHDA_00982 566552.BIFCAT_01550 0.0 1487.0 COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4CYZ1@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.196,3.2.1.68 ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 BHPHKHDA_00983 216816.GS08_09130 9.6e-106 306.0 COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,4CZ9Y@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 BHPHKHDA_00984 326426.Bbr_1649 5.33e-103 298.0 COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4D0PV@85004|Bifidobacteriales 201174|Actinobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 BHPHKHDA_00985 326426.Bbr_1650 0.0 1444.0 COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZC7@85004|Bifidobacteriales 201174|Actinobacteria G 4-alpha-glucanotransferase malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 BHPHKHDA_00986 326426.Bbr_1651 9.47e-152 427.0 2BMRI@1|root,32GAY@2|Bacteria,2GMIA@201174|Actinobacteria,4CZFZ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - LRV BHPHKHDA_00987 326426.Bbr_1652 9.37e-142 401.0 COG1739@1|root,COG1739@2|Bacteria,2GMM4@201174|Actinobacteria,4CZH8@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized protein family UPF0029 yigZ - - - - - - - - - - - DUF1949,UPF0029 BHPHKHDA_00988 326426.Bbr_1653 6.76e-233 641.0 COG0111@1|root,COG0111@2|Bacteria,2GKTT@201174|Actinobacteria,4CZRS@85004|Bifidobacteriales 201174|Actinobacteria EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family pdxB - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C BHPHKHDA_00989 216816.GS08_09160 3.07e-19 87.0 COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4D081@85004|Bifidobacteriales 201174|Actinobacteria M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap BHPHKHDA_00990 1437610.BREU_0592 2.49e-47 165.0 COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4D081@85004|Bifidobacteriales 201174|Actinobacteria M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap BHPHKHDA_00991 326426.Bbr_0418 2.08e-131 378.0 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZX2@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00992 326426.Bbr_0528 4.98e-226 624.0 COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4CYV5@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_00993 326426.Bbr_0529 0.0 1440.0 COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 bga1 - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M BHPHKHDA_00994 326426.Bbr_0530 0.0 900.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_00995 326426.Bbr_0531 0.0 957.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_00996 326426.Bbr_0532 1.29e-183 510.0 COG1521@1|root,COG1521@2|Bacteria,2GMRQ@201174|Actinobacteria,4CZQS@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase BHPHKHDA_00997 326426.Bbr_0533 0.0 1054.0 COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4CYWF@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 BHPHKHDA_00998 326426.Bbr_0534 1.57e-214 594.0 COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4CYST@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 BHPHKHDA_00999 326426.Bbr_0535 4.22e-193 540.0 COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria,4CZ84@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 BHPHKHDA_01000 326426.Bbr_0536 6.51e-176 491.0 COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria,4CZ3U@85004|Bifidobacteriales 201174|Actinobacteria EP oligopeptide transport protein of the ABC superfamily, ATP-binding component - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran BHPHKHDA_01001 326426.Bbr_0537 1.6e-175 490.0 COG4608@1|root,COG4608@2|Bacteria,2GP46@201174|Actinobacteria,4CYXD@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran BHPHKHDA_01002 326426.Bbr_0538 8.21e-245 672.0 COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CYQ4@85004|Bifidobacteriales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme cbs GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - CBS,PALP BHPHKHDA_01003 326426.Bbr_0539 1.02e-279 765.0 COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4CYY2@85004|Bifidobacteriales 201174|Actinobacteria E Cys/Met metabolism PLP-dependent enzyme metB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1079 Cys_Met_Meta_PP BHPHKHDA_01004 326426.Bbr_0540 0.0 1258.0 COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CZ0I@85004|Bifidobacteriales 201174|Actinobacteria L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind BHPHKHDA_01005 326426.Bbr_0541 4.78e-120 342.0 COG1854@1|root,COG1854@2|Bacteria,2GJVF@201174|Actinobacteria,4CYZ4@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS BHPHKHDA_01006 326426.Bbr_0542 4.31e-133 376.0 COG1670@1|root,COG1670@2|Bacteria,2HBE2@201174|Actinobacteria,4CZTR@85004|Bifidobacteriales 201174|Actinobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins cysE - - - - - - - - - - - - BHPHKHDA_01007 326426.Bbr_0543 0.0 942.0 COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 aap1 - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 BHPHKHDA_01008 326426.Bbr_0544 0.0 899.0 COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CZ2Q@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N BHPHKHDA_01009 326426.Bbr_0545 1.14e-307 838.0 COG0232@1|root,COG0232@2|Bacteria,2GJ8F@201174|Actinobacteria,4CYYP@85004|Bifidobacteriales 201174|Actinobacteria F Phosphohydrolase-associated domain dgt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc BHPHKHDA_01010 326426.Bbr_0546 0.0 1370.0 COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,4CYZG@85004|Bifidobacteriales 201174|Actinobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 BHPHKHDA_01011 326426.Bbr_0547 8.7e-91 266.0 COG1848@1|root,COG1848@2|Bacteria,2INKB@201174|Actinobacteria,4D149@85004|Bifidobacteriales 201174|Actinobacteria S PIN domain - - - - - - - - - - - - PIN_3 BHPHKHDA_01012 326426.Bbr_0548 1.15e-47 152.0 2EH4D@1|root,33AWC@2|Bacteria,2GZXK@201174|Actinobacteria,4D1PF@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01013 326426.Bbr_0549 1.63e-199 553.0 COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CZ5P@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ BHPHKHDA_01014 326426.Bbr_0550 1.2e-148 418.0 COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4CYUS@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO BHPHKHDA_01015 326426.Bbr_0551 0.0 999.0 COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4CZGJ@85004|Bifidobacteriales 201174|Actinobacteria EK Alanine-glyoxylate amino-transferase - - - ko:K03710,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR BHPHKHDA_01016 326426.Bbr_0552 9.59e-268 734.0 COG1055@1|root,COG1055@2|Bacteria,2GP6U@201174|Actinobacteria,4CZ37@85004|Bifidobacteriales 201174|Actinobacteria P Citrate transporter - - - - - - - - - - - - CitMHS BHPHKHDA_01017 326426.Bbr_0553 9.8e-41 134.0 2B4W6@1|root,31XNV@2|Bacteria,2GZB9@201174|Actinobacteria,4D1T7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01018 216816.GS08_02865 2.24e-50 178.0 COG3534@1|root,COG3534@2|Bacteria,2GP9Z@201174|Actinobacteria,4CZ95@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-L-arabinofuranosidase C-terminal domain - - - - - - - - - - - - Alpha-L-AF_C,Big_3_5,CBM_4_9,DUF1349,Laminin_G_3 BHPHKHDA_01019 326426.Bbr_0555 2.93e-201 558.0 COG1737@1|root,COG1737@2|Bacteria,2HY2W@201174|Actinobacteria,4D050@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS BHPHKHDA_01022 326426.Bbr_0557 0.0 890.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4CYRE@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_01023 326426.Bbr_0558 9.75e-295 805.0 COG1609@1|root,COG1609@2|Bacteria,2GJDS@201174|Actinobacteria,4CZR6@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_1,Peripla_BP_3 BHPHKHDA_01024 216816.GS08_01605 1.43e-63 203.0 COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,4CZ5C@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives tnp3503b - - - - - - - - - - - Transposase_mut BHPHKHDA_01025 1437608.BBIA_0810 1.44e-42 139.0 2EJJI@1|root,33DAG@2|Bacteria,2GW42@201174|Actinobacteria,4D1C7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01026 1437608.BBIA_0809 7.33e-183 510.0 2B0U3@1|root,31T6M@2|Bacteria,2IDXF@201174|Actinobacteria,4D01Y@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - TrbL BHPHKHDA_01027 1437609.BCAL_0558 1.64e-86 254.0 29YW1@1|root,30KSH@2|Bacteria,2HZKD@201174|Actinobacteria,4D0T1@85004|Bifidobacteriales 201174|Actinobacteria S PrgI family protein - - - - - - - - - - - - PrgI BHPHKHDA_01028 1437609.BCAL_0559 0.0 1534.0 COG3451@1|root,COG3451@2|Bacteria,2H6W2@201174|Actinobacteria,4CYWV@85004|Bifidobacteriales 201174|Actinobacteria U type IV secretory pathway VirB4 - - - - - - - - - - - - DUF87 BHPHKHDA_01029 1437610.BREU_1713 0.0 918.0 COG0741@1|root,COG3942@1|root,COG0741@2|Bacteria,COG3942@2|Bacteria,2I9VT@201174|Actinobacteria,4D074@85004|Bifidobacteriales 201174|Actinobacteria M CHAP domain - - - - - - - - - - - - CHAP,SLT BHPHKHDA_01030 1437608.BBIA_0804 8.71e-242 671.0 2AQRU@1|root,31FZM@2|Bacteria,2IABZ@201174|Actinobacteria,4D0HM@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01032 1437609.BCAL_0562 5.72e-83 254.0 2BM4R@1|root,32FN7@2|Bacteria,2HZNA@201174|Actinobacteria,4D0ZT@85004|Bifidobacteriales 201174|Actinobacteria S Putative amidase domain - - - - - - - - - - - - Amidase_6 BHPHKHDA_01033 1437610.BREU_1710 1.82e-126 368.0 2BM4R@1|root,32FN7@2|Bacteria,2HZNA@201174|Actinobacteria,4D0ZT@85004|Bifidobacteriales 201174|Actinobacteria S Putative amidase domain - - - - - - - - - - - - Amidase_6 BHPHKHDA_01034 1437609.BCAL_0563 0.0 1103.0 COG3505@1|root,COG3505@2|Bacteria,2HZ9D@201174|Actinobacteria,4CZ1V@85004|Bifidobacteriales 201174|Actinobacteria U Type IV secretory system Conjugative DNA transfer - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf,TraG-D_C BHPHKHDA_01035 1437609.BCAL_0564 7.51e-78 234.0 2B770@1|root,32091@2|Bacteria,2H3T0@201174|Actinobacteria,4D1X5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01036 1437609.BCAL_0565 4.83e-61 188.0 2B4MV@1|root,31XE5@2|Bacteria,2GYVS@201174|Actinobacteria,4D1SI@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01037 1437609.BCAL_0566 5.89e-161 452.0 2A0I7@1|root,30NNC@2|Bacteria,2H22C@201174|Actinobacteria,4D1YZ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01038 1437610.BREU_1705 0.0 917.0 COG4734@1|root,COG4734@2|Bacteria,2ICX2@201174|Actinobacteria,4D0K8@85004|Bifidobacteriales 201174|Actinobacteria S Antirestriction protein (ArdA) - - - - - - - - - - - - ArdA BHPHKHDA_01039 1437609.BCAL_0568 4.93e-220 609.0 29W77@1|root,30HSE@2|Bacteria,2IKED@201174|Actinobacteria,4D0WN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01040 1437609.BCAL_0569 2.72e-207 574.0 2BIEZ@1|root,31NAI@2|Bacteria,2IGEY@201174|Actinobacteria,4D0TK@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3801) - - - - - - - - - - - - DUF3801 BHPHKHDA_01041 1437609.BCAL_0570 0.0 938.0 COG3843@1|root,COG3843@2|Bacteria,2GKSD@201174|Actinobacteria,4CZZ8@85004|Bifidobacteriales 201174|Actinobacteria U Relaxase/Mobilisation nuclease domain - - - - - - - - - - - - Relaxase BHPHKHDA_01042 1437609.BCAL_0571 2.35e-92 270.0 2DIGM@1|root,3037U@2|Bacteria,2IRFD@201174|Actinobacteria,4D1BD@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial mobilisation protein (MobC) - - - - - - - - - - - - MobC BHPHKHDA_01043 1437609.BCAL_0572 1.85e-110 318.0 29Q6E@1|root,30B5C@2|Bacteria,2GVH6@201174|Actinobacteria,4D1MH@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01044 1437609.BCAL_0573 2.58e-62 192.0 2B0RI@1|root,31T3S@2|Bacteria,2GRPB@201174|Actinobacteria,4D1JJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01045 1437609.BCAL_0574 0.0 945.0 COG1475@1|root,COG1475@2|Bacteria,2I9G6@201174|Actinobacteria,4D06E@85004|Bifidobacteriales 201174|Actinobacteria K ParB-like nuclease domain - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc BHPHKHDA_01046 1437609.BCAL_0575 1.15e-138 392.0 2B5AP@1|root,31VDH@2|Bacteria,2GVFX@201174|Actinobacteria,4D1E8@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4192) - - - - - - - - - - - - DUF4192 BHPHKHDA_01047 1437609.BCAL_0576 1.45e-296 811.0 COG4585@1|root,COG4585@2|Bacteria,2GVYN@201174|Actinobacteria,4D1I8@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 BHPHKHDA_01048 1437609.BCAL_0577 1.55e-160 450.0 COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4D0EU@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg BHPHKHDA_01049 1437609.BCAL_0578 2.21e-156 439.0 COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4D00Y@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01050 1437609.BCAL_0579 1.06e-24 92.0 2BEP0@1|root,328EK@2|Bacteria,2HE79@201174|Actinobacteria,4D2MJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01051 1437609.BCAL_0580 0.0 1004.0 COG0367@1|root,COG0367@2|Bacteria,2GMIY@201174|Actinobacteria,4D1Z9@85004|Bifidobacteriales 201174|Actinobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase BHPHKHDA_01052 1437610.BREU_1692 2.87e-42 152.0 COG0367@1|root,COG0367@2|Bacteria,2GMIY@201174|Actinobacteria,4D1Z9@85004|Bifidobacteriales 201174|Actinobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase BHPHKHDA_01053 1437610.BREU_1690 0.0 1060.0 COG1132@1|root,COG1132@2|Bacteria,2GJTA@201174|Actinobacteria,4D20I@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran,Transglut_core3 BHPHKHDA_01055 649743.HMPREF0972_00932 9.4e-187 578.0 2C4IS@1|root,2Z81U@2|Bacteria,2GP0Z@201174|Actinobacteria,4D71C@85005|Actinomycetales 201174|Actinobacteria S Thiopeptide-type bacteriocin biosynthesis domain protein - - - ko:K20483 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - Lant_dehydr_C,Lant_dehydr_N BHPHKHDA_01056 1227261.HMPREF0043_01257 1.44e-131 394.0 COG4403@1|root,COG4403@2|Bacteria,2GPKJ@201174|Actinobacteria,4D73I@85005|Actinomycetales 201174|Actinobacteria V Psort location Cytoplasmic, score - - - ko:K20484 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - LANC_like BHPHKHDA_01058 702459.BBPR_1115 3.22e-146 422.0 COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria,4CZBZ@85004|Bifidobacteriales 201174|Actinobacteria V VanZ like family - - - - - - - - - - - - RDD,VanZ BHPHKHDA_01060 216816.GS08_00255 2.13e-94 275.0 COG3255@1|root,COG3255@2|Bacteria,2IQBF@201174|Actinobacteria,4D10H@85004|Bifidobacteriales 201174|Actinobacteria I Sterol carrier protein - - - - - - - - - - - - MDMPI_C,MDMPI_N BHPHKHDA_01061 216816.GS08_00250 8.23e-294 806.0 COG0477@1|root,COG0477@2|Bacteria,2I3AP@201174|Actinobacteria,4D0YC@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_01062 216816.GS08_00245 6.47e-266 729.0 COG4585@1|root,COG4585@2|Bacteria,2IC0A@201174|Actinobacteria,4D04K@85004|Bifidobacteriales 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - - BHPHKHDA_01063 216816.GS08_00240 4.6e-147 415.0 COG2197@1|root,COG2197@2|Bacteria,2IF55@201174|Actinobacteria,4D0XW@85004|Bifidobacteriales 201174|Actinobacteria K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - - - - - - - - - - GerE,Response_reg BHPHKHDA_01064 326426.Bbr_0058 2.08e-58 183.0 2EGRW@1|root,32FNP@2|Bacteria,2HZNH@201174|Actinobacteria,4D120@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3073) - - - - - - - - - - - - DUF3073 BHPHKHDA_01065 216816.GS08_00230 5.93e-261 715.0 COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4CYXM@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b BHPHKHDA_01066 326426.Bbr_0056 0.0 1030.0 COG1574@1|root,COG1574@2|Bacteria,2GJVW@201174|Actinobacteria,4CZQ4@85004|Bifidobacteriales 201174|Actinobacteria S Amidohydrolase family - - - - - - - - - - - - Amidohydro_3 BHPHKHDA_01067 326426.Bbr_0055 4.81e-227 626.0 COG2852@1|root,COG2852@2|Bacteria,2GN40@201174|Actinobacteria,4CZPZ@85004|Bifidobacteriales 201174|Actinobacteria S Protein conserved in bacteria - - - - - - - - - - - - DUF559 BHPHKHDA_01068 326426.Bbr_0054 1.57e-53 181.0 COG0591@1|root,COG0591@2|Bacteria,2I041@201174|Actinobacteria,4CZS2@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - ko:K11928 - - - - ko00000,ko02000 2.A.21.2 - - SSF BHPHKHDA_01069 326426.Bbr_0053 0.0 1246.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,2HZ8C@201174|Actinobacteria,4CYR2@85004|Bifidobacteriales 201174|Actinobacteria S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE,ThrE_2 BHPHKHDA_01070 326426.Bbr_0052 0.0 1747.0 COG2352@1|root,COG2352@2|Bacteria,2GKDB@201174|Actinobacteria,4CZS0@85004|Bifidobacteriales 201174|Actinobacteria H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase BHPHKHDA_01071 326426.Bbr_0051 0.0 1059.0 COG1414@1|root,COG2865@1|root,COG1414@2|Bacteria,COG2865@2|Bacteria,2I3IG@201174|Actinobacteria,4CZRW@85004|Bifidobacteriales 201174|Actinobacteria K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4,MarR_2 BHPHKHDA_01072 326426.Bbr_0050 1.27e-118 342.0 COG1373@1|root,COG1373@2|Bacteria,2HCYQ@201174|Actinobacteria,4D2TP@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_01073 326426.Bbr_0049 0.0 1460.0 COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,2I2FR@201174|Actinobacteria,4D09B@85004|Bifidobacteriales 201174|Actinobacteria T Putative diguanylate phosphodiesterase - - 3.1.4.52 ko:K14051 ko02024,ko02026,map02024,map02026 - - - ko00000,ko00001,ko01000 - - - EAL,GGDEF,PAS,PAS_3,PAS_4 BHPHKHDA_01074 326426.Bbr_0048 4.71e-140 397.0 COG1285@1|root,COG1285@2|Bacteria,2HZFV@201174|Actinobacteria,4D0AX@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4956) - - - - - - - - - - - - DUF4956 BHPHKHDA_01075 216816.GS08_07945 1.63e-195 542.0 COG5036@1|root,COG5036@2|Bacteria,2HZIY@201174|Actinobacteria,4D0MA@85004|Bifidobacteriales 201174|Actinobacteria P VTC domain - - - - - - - - - - - - VTC BHPHKHDA_01076 216816.GS08_07950 0.0 1130.0 COG5337@1|root,COG5337@2|Bacteria,2ID5Z@201174|Actinobacteria,4D02F@85004|Bifidobacteriales 201174|Actinobacteria M CotH kinase protein - - - ko:K06330 - - - - ko00000 - - - CotH BHPHKHDA_01077 547043.BIFPSEUDO_02522 0.0 939.0 COG4267@1|root,COG4267@2|Bacteria,2IE76@201174|Actinobacteria,4CZ7D@85004|Bifidobacteriales 201174|Actinobacteria S Putative exopolysaccharide Exporter (EPS-E) - - - ko:K21012 ko02025,map02025 - - - ko00000,ko00001 - - - PelG BHPHKHDA_01078 326426.Bbr_0044 0.0 870.0 COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,4CZ5G@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF3492) - - - ko:K21011 ko02025,map02025 - - - ko00000,ko00001,ko01003 - GT4 - DUF3492,Glyco_trans_1_4,Glycos_transf_1 BHPHKHDA_01079 216816.GS08_07960 3.7e-19 85.1 COG0438@1|root,COG0438@2|Bacteria,2GKEA@201174|Actinobacteria,4CZ5G@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF3492) - - - ko:K21011 ko02025,map02025 - - - ko00000,ko00001,ko01003 - GT4 - DUF3492,Glyco_trans_1_4,Glycos_transf_1 BHPHKHDA_01080 216816.GS08_07965 0.0 1139.0 COG4878@1|root,COG4878@2|Bacteria,2IERA@201174|Actinobacteria,4D00K@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterised protein conserved in bacteria (DUF2194) - - - - - - - - - - - - DUF2194 BHPHKHDA_01081 326426.Bbr_0041 1.51e-206 572.0 28H6W@1|root,2Z7J7@2|Bacteria,2ICGP@201174|Actinobacteria,4CZUA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01082 216816.GS08_07975 0.0 1385.0 COG0451@1|root,COG0451@2|Bacteria,2ICHN@201174|Actinobacteria,4CYZ7@85004|Bifidobacteriales 201174|Actinobacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase BHPHKHDA_01083 326426.Bbr_0599 6.66e-298 814.0 COG0027@1|root,COG0027@2|Bacteria,2GMCS@201174|Actinobacteria,4CZXH@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate purT GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008776,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044444,GO:0044464 2.1.2.2 ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0389 ATP-grasp,Epimerase BHPHKHDA_01084 326426.Bbr_0598 1.14e-174 487.0 COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CZGQ@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt BHPHKHDA_01085 326426.Bbr_0597 0.0 2389.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,2GKG6@201174|Actinobacteria,4CZ7C@85004|Bifidobacteriales 201174|Actinobacteria F CobB/CobQ-like glutamine amidotransferase domain purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,GATase_5 BHPHKHDA_01086 216816.GS08_03045 8.75e-298 814.0 COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4CYYK@85004|Bifidobacteriales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 BHPHKHDA_01087 216816.GS08_03040 0.0 877.0 COG1020@1|root,COG1020@2|Bacteria,2H4CN@201174|Actinobacteria,4D0AP@85004|Bifidobacteriales 201174|Actinobacteria Q D-alanine [D-alanyl carrier protein] ligase activity - - - - - - - - - - - - - BHPHKHDA_01088 216816.GS08_03035 3.12e-143 405.0 COG1020@1|root,COG1020@2|Bacteria,2GIS8@201174|Actinobacteria,4D0BP@85004|Bifidobacteriales 201174|Actinobacteria Q D-alanine [D-alanyl carrier protein] ligase activity - - - - - - - - - - - - - BHPHKHDA_01089 326426.Bbr_0588 1.96e-131 372.0 COG3663@1|root,COG3663@2|Bacteria,2IGMS@201174|Actinobacteria,4D0QQ@85004|Bifidobacteriales 201174|Actinobacteria L Uracil DNA glycosylase superfamily nnrE - - - - - - - - - - - UDG,YjeF_N BHPHKHDA_01090 216816.GS08_02990 1.95e-19 80.1 COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4CZ8K@85004|Bifidobacteriales 201174|Actinobacteria C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red BHPHKHDA_01091 326426.Bbr_0586 1.63e-43 141.0 2DTWH@1|root,33MZC@2|Bacteria,2GUGG@201174|Actinobacteria,4D1FM@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01092 326426.Bbr_0585 0.0 1032.0 COG0389@1|root,COG0389@2|Bacteria,2GQX7@201174|Actinobacteria,4CZ0D@85004|Bifidobacteriales 201174|Actinobacteria L DNA-damage repair protein (DNA polymerase IV) K00961 - - - ko:K03502 - - - - ko00000,ko03400 - - - IMS,IMS_C,IMS_HHH BHPHKHDA_01093 326426.Bbr_0584 0.0 1004.0 COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CZ89@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0008150,GO:0040007 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran BHPHKHDA_01094 326426.Bbr_0583 6.44e-240 660.0 COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,4CZ3K@85004|Bifidobacteriales 201174|Actinobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C BHPHKHDA_01095 326426.Bbr_0582 7.04e-308 838.0 COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4CZ3I@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the GARS family purD GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N BHPHKHDA_01096 326426.Bbr_0581 0.0 1013.0 COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4CZQF@85004|Bifidobacteriales 201174|Actinobacteria C Aldehyde dehydrogenase family aldH - 1.2.1.3,1.2.99.10 ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh BHPHKHDA_01097 326426.Bbr_0580 0.0 1330.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase BHPHKHDA_01098 326426.Bbr_0579 7.06e-198 551.0 COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4CZ99@85004|Bifidobacteriales 201174|Actinobacteria P Zinc-uptake complex component A periplasmic - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA BHPHKHDA_01099 326426.Bbr_0569 6.55e-93 271.0 COG0735@1|root,COG0735@2|Bacteria,2IKS3@201174|Actinobacteria,4D0XG@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the Fur family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR BHPHKHDA_01100 216816.GS08_02915 3.18e-282 771.0 COG0026@1|root,COG0026@2|Bacteria,2GJCU@201174|Actinobacteria,4CYWP@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp BHPHKHDA_01101 326426.Bbr_0567 3.44e-110 317.0 COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CYQZ@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE GO:0008150,GO:0040007 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3275c AIRC BHPHKHDA_01102 326426.Bbr_0566 3.27e-230 634.0 COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4D00X@85004|Bifidobacteriales 201174|Actinobacteria C Zinc-binding dehydrogenase yogA - - - - - - - - - - - ADH_N,ADH_zinc_N BHPHKHDA_01103 326426.Bbr_0565 0.0 1353.0 COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,4CZ2M@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C BHPHKHDA_01104 326426.Bbr_0564 0.0 978.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GIRW@201174|Actinobacteria,4CZMQ@85004|Bifidobacteriales 201174|Actinobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BHPHKHDA_01105 326426.Bbr_0563 3.69e-248 688.0 COG1361@1|root,COG1361@2|Bacteria,2GP6I@201174|Actinobacteria,4D013@85004|Bifidobacteriales 201174|Actinobacteria M Conserved repeat domain - - - - - - - - - - - - - BHPHKHDA_01106 326426.Bbr_0562 1.54e-182 509.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4D2SJ@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - GO:0008150,GO:0009405,GO:0009605,GO:0009607,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX BHPHKHDA_01107 78346.BRUM_1549 1.78e-241 674.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZ2P@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 3 N-terminal domain protein bglB - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C BHPHKHDA_01108 326426.Bbr_1435 1.75e-117 337.0 COG1846@1|root,COG1846@2|Bacteria,2IIWT@201174|Actinobacteria,4D0WT@85004|Bifidobacteriales 201174|Actinobacteria K MarR family - - - - - - - - - - - - MarR,MarR_2 BHPHKHDA_01109 216816.GS08_07930 0.0 1139.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZMX@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BHPHKHDA_01110 326426.Bbr_1433 0.0 1287.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZPJ@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BHPHKHDA_01111 216816.GS08_07920 1.69e-171 487.0 COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4CZNG@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 BHPHKHDA_01112 1120933.ATUY01000006_gene1213 6.44e-177 499.0 COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4D4IS@85005|Actinomycetales 201174|Actinobacteria F Inosine-uridine preferring nucleoside hydrolase - - 3.2.2.1 ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 - R01245,R01273,R01677,R01770,R02143 RC00033,RC00063,RC00122,RC00318,RC00485 ko00000,ko00001,ko01000 - - - IU_nuc_hydro BHPHKHDA_01113 1193128.A200_02539 8.7e-214 605.0 COG0477@1|root,COG0477@2|Bacteria,2GJV6@201174|Actinobacteria,4CZH3@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K08168 - M00704 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.6 - - MFS_1 BHPHKHDA_01114 326426.Bbr_1415 7.24e-185 520.0 COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB BHPHKHDA_01115 326426.Bbr_1414 0.0 2235.0 COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CYT7@85004|Bifidobacteriales 201174|Actinobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1 BHPHKHDA_01116 1437609.BCAL_0365 1e-76 237.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 BHPHKHDA_01117 326426.Bbr_1411 0.0 1588.0 COG1203@1|root,COG1203@2|Bacteria,2IC92@201174|Actinobacteria,4D0E8@85004|Bifidobacteriales 201174|Actinobacteria L DEAD-like helicases superfamily cas3 - - ko:K07012 - - - - ko00000,ko01000,ko02048 - - - DEAD,HD,Helicase_C,ResIII BHPHKHDA_01118 326426.Bbr_1410 9.86e-177 491.0 2DBAF@1|root,2Z82V@2|Bacteria,2IDEP@201174|Actinobacteria,4CYQ7@85004|Bifidobacteriales 201174|Actinobacteria S CRISPR-associated protein (Cas_Cas5) cas5d - - ko:K19119 - - - - ko00000,ko02048 - - - Cas_Cas5d BHPHKHDA_01119 326426.Bbr_1409 0.0 1310.0 COG5632@1|root,COG5632@2|Bacteria,2IAY1@201174|Actinobacteria,4CZ5Z@85004|Bifidobacteriales 201174|Actinobacteria M CRISPR-associated protein (Cas_Csd1) - - - ko:K19117 - - - - ko00000,ko02048 - - - Cas_Csd1 BHPHKHDA_01120 326426.Bbr_1408 5.28e-201 556.0 COG3649@1|root,COG3649@2|Bacteria,2H4JU@201174|Actinobacteria,4CZQ5@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR-associated protein Cas7 - - - ko:K19118 - - - - ko00000,ko02048 - - - Cas_Cas7 BHPHKHDA_01121 326426.Bbr_1407 3.43e-170 474.0 COG1468@1|root,COG1468@2|Bacteria,2IAV6@201174|Actinobacteria,4D0B8@85004|Bifidobacteriales 201174|Actinobacteria L Domain of unknown function DUF83 cas4 - 3.1.12.1 ko:K07464,ko:K15342 - - - - ko00000,ko01000,ko02048,ko03400 - - - Cas_Cas4 BHPHKHDA_01122 326426.Bbr_1406 5.83e-251 688.0 COG1518@1|root,COG1518@2|Bacteria,2I8M0@201174|Actinobacteria,4CZYS@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1,Cas_Cas4 BHPHKHDA_01123 326426.Bbr_1405 1.65e-48 155.0 COG1343@1|root,COG1343@2|Bacteria,2ISFY@201174|Actinobacteria,4D16B@85004|Bifidobacteriales 201174|Actinobacteria L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 BHPHKHDA_01126 326426.Bbr_1551 3.28e-36 134.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 gph - - ko:K16209 - - - - ko00000,ko02000 2.A.2.2 - - MFS_2 BHPHKHDA_01127 1273125.Rrhod_4101 8.13e-18 83.6 COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria,4FUV7@85025|Nocardiaceae 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase BHPHKHDA_01128 78346.BRUM_1919 8.73e-35 124.0 COG1569@1|root,COG1569@2|Bacteria,2IMP1@201174|Actinobacteria,4D13G@85004|Bifidobacteriales 201174|Actinobacteria S PIN domain - - - - - - - - - - - - PIN_3 BHPHKHDA_01129 78346.BRUM_1918 2.32e-58 183.0 2BM73@1|root,32FQT@2|Bacteria,2HZUH@201174|Actinobacteria,4D1TW@85004|Bifidobacteriales 201174|Actinobacteria S Helix-turn-helix domain - - - - - - - - - - - - HTH_17 BHPHKHDA_01130 1147128.BAST_0873 0.0 2808.0 COG3087@1|root,COG3087@2|Bacteria,2HRQY@201174|Actinobacteria,4CYQ9@85004|Bifidobacteriales 201174|Actinobacteria D Cell surface antigen C-terminus - - - - - - - - - - - - Antigen_C BHPHKHDA_01131 326426.Bbr_1517 2.32e-152 428.0 COG0560@1|root,COG0560@2|Bacteria,2HZV3@201174|Actinobacteria,4D1VN@85004|Bifidobacteriales 201174|Actinobacteria E haloacid dehalogenase-like hydrolase - - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD BHPHKHDA_01132 326426.Bbr_1516 2.17e-122 349.0 COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria,4D1CY@85004|Bifidobacteriales 201174|Actinobacteria K FR47-like protein - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 BHPHKHDA_01133 216816.GS08_08570 0.0 991.0 COG0488@1|root,COG0488@2|Bacteria,2GKZC@201174|Actinobacteria,4CZ9C@85004|Bifidobacteriales 201174|Actinobacteria S ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran BHPHKHDA_01134 326426.Bbr_1514 7.39e-54 168.0 2AYK3@1|root,31QQD@2|Bacteria,2ISGT@201174|Actinobacteria,4D1C9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01135 326426.Bbr_1513 3.57e-130 370.0 COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria,4D14U@85004|Bifidobacteriales 201174|Actinobacteria D AAA domain - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA BHPHKHDA_01136 1147128.BAST_0865 1.47e-111 323.0 2A2Z4@1|root,30RDK@2|Bacteria,2IDG0@201174|Actinobacteria,4D038@85004|Bifidobacteriales 201174|Actinobacteria S Transcription factor WhiB - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib BHPHKHDA_01137 1147128.BAST_0864 6.06e-274 754.0 29W79@1|root,30HSG@2|Bacteria,2IC42@201174|Actinobacteria,4CZCZ@85004|Bifidobacteriales 201174|Actinobacteria S Helix-turn-helix domain - - - - - - - - - - - - HTH_36 BHPHKHDA_01138 1147128.BAST_0864 1.19e-15 75.9 29W79@1|root,30HSG@2|Bacteria,2IC42@201174|Actinobacteria,4CZCZ@85004|Bifidobacteriales 201174|Actinobacteria S Helix-turn-helix domain - - - - - - - - - - - - HTH_36 BHPHKHDA_01140 326426.Bbr_1508 1.49e-88 266.0 2AQMV@1|root,31FV1@2|Bacteria,2IEG5@201174|Actinobacteria,4D0KQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - BetR BHPHKHDA_01141 1437609.BCAL_0606 4.32e-298 813.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family intA - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase BHPHKHDA_01142 1437609.BCAL_0605 1.55e-103 304.0 2DQQK@1|root,33842@2|Bacteria,2GS39@201174|Actinobacteria,4D0HX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - HTH_17 BHPHKHDA_01143 1437609.BCAL_0604 4.61e-167 468.0 29YC4@1|root,30K6H@2|Bacteria,2H0Z2@201174|Actinobacteria,4D0DD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - AbiEii BHPHKHDA_01146 1437609.BCAL_0599 6.67e-311 847.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4CZA9@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase family intA - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase BHPHKHDA_01147 1437609.BCAL_0598 1.78e-43 156.0 COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 20, domain 2 - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b BHPHKHDA_01148 1437609.BCAL_0598 7.61e-72 234.0 COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 20, domain 2 - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b BHPHKHDA_01149 326426.Bbr_1556 3.67e-172 499.0 COG3525@1|root,COG3525@2|Bacteria,2HZCI@201174|Actinobacteria,4CZS1@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 20, domain 2 - - - - - - - - - - - - Glyco_hydro_20,Glyco_hydro_20b BHPHKHDA_01150 1437609.BCAL_0541 1.23e-35 132.0 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 gph - - ko:K16209 - - - - ko00000,ko02000 2.A.2.2 - - MFS_2 BHPHKHDA_01152 216816.GS08_05135 8.73e-154 432.0 COG1131@1|root,COG1131@2|Bacteria,2IEJK@201174|Actinobacteria,4D0K4@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01153 216816.GS08_05140 3.3e-138 394.0 2EXFX@1|root,33QS8@2|Bacteria,2IC7Z@201174|Actinobacteria,4CZUQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01154 762211.BSTEL_0148 2.76e-104 306.0 2F10A@1|root,33U1T@2|Bacteria,2IAKS@201174|Actinobacteria,4D01S@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01157 58344.JOEL01000018_gene5379 5.75e-50 172.0 COG1131@1|root,COG1131@2|Bacteria 2|Bacteria V ATPase activity - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01158 403833.Pmob_0666 2.3e-56 189.0 COG0842@1|root,COG0842@2|Bacteria,2GBXF@200918|Thermotogae 200918|Thermotogae V PFAM ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane BHPHKHDA_01159 1437608.BBIA_0816 0.0 2752.0 COG3064@1|root,COG3064@2|Bacteria,2I2HK@201174|Actinobacteria,4D2VM@85004|Bifidobacteriales 201174|Actinobacteria M Cell surface antigen C-terminus - - - - - - - - - - - - Antigen_C BHPHKHDA_01161 77635.BISU_1251 6.52e-157 454.0 COG2856@1|root,COG2856@2|Bacteria,2GRH0@201174|Actinobacteria 201174|Actinobacteria K Helix-turn-helix domain protein - - - - - - - - - - - - HTH_3,Peptidase_M78 BHPHKHDA_01162 1437608.BBIA_0818 2.46e-36 125.0 2B6SJ@1|root,31ZRP@2|Bacteria,2IQ17@201174|Actinobacteria,4D142@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01163 1437609.BCAL_0537 1.03e-91 268.0 2BH3J@1|root,32B4F@2|Bacteria,2IHK5@201174|Actinobacteria,4D0RP@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01164 1437608.BBIA_0820 1.43e-47 152.0 2AYK3@1|root,31QQD@2|Bacteria,2ISGT@201174|Actinobacteria,4D1C9@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01165 1437608.BBIA_0821 5.1e-134 380.0 COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria,4D14U@85004|Bifidobacteriales 201174|Actinobacteria D AAA domain - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA BHPHKHDA_01166 1437609.BCAL_0534 3.71e-127 361.0 2A2Z4@1|root,30RDK@2|Bacteria,2IDG0@201174|Actinobacteria,4D038@85004|Bifidobacteriales 201174|Actinobacteria S Transcription factor WhiB - - - ko:K18955 - - - - ko00000,ko03000 - - - Whib BHPHKHDA_01167 326426.Bbr_0905 0.0 1113.0 COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CYWE@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1699 CTP_synth_N,GATase BHPHKHDA_01168 326426.Bbr_0906 0.0 1068.0 COG1376@1|root,COG1376@2|Bacteria,2GQ7D@201174|Actinobacteria,4CZ5A@85004|Bifidobacteriales 201174|Actinobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - PG_binding_4,YkuD BHPHKHDA_01169 326426.Bbr_0907 0.0 1004.0 COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CZPQ@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly protein SufB sufB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - ko:K09014 - - - - ko00000 - - - UPF0051 BHPHKHDA_01170 326426.Bbr_0908 1.24e-300 819.0 COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CZEE@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly protein SufD sufD GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - ko:K09015 - - - - ko00000 - - - UPF0051 BHPHKHDA_01171 326426.Bbr_0909 2.81e-184 512.0 COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CZU1@85004|Bifidobacteriales 201174|Actinobacteria O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran BHPHKHDA_01172 326426.Bbr_0910 1.25e-302 825.0 COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CZIU@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 BHPHKHDA_01173 326426.Bbr_0911 4.82e-132 374.0 COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,4CZU5@85004|Bifidobacteriales 201174|Actinobacteria C SUF system FeS assembly protein, NifU family iscU - - ko:K04488 - - - - ko00000 - - - NifU_N BHPHKHDA_01174 326426.Bbr_0912 2.19e-142 401.0 COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria,4CYRH@85004|Bifidobacteriales 201174|Actinobacteria S Iron-sulfur cluster assembly protein - - - - - - - - - - - - FeS_assembly_P BHPHKHDA_01175 326426.Bbr_0913 3.09e-307 836.0 COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4CZ4E@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase BHPHKHDA_01176 326426.Bbr_0914 7.89e-212 585.0 COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4CYQ6@85004|Bifidobacteriales 201174|Actinobacteria J SpoU rRNA Methylase family spoU2 - - - - - - - - - - - SpoU_methylase BHPHKHDA_01178 326426.Bbr_0915 1.21e-192 536.0 COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,4CZAD@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA BHPHKHDA_01179 326426.Bbr_0916 2.76e-76 227.0 COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4D130@85004|Bifidobacteriales 201174|Actinobacteria FG Scavenger mRNA decapping enzyme C-term binding hit - - ko:K02503 - - - - ko00000,ko04147 - - - DcpS_C,HIT BHPHKHDA_01180 326426.Bbr_0917 3.27e-276 756.0 COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,4CZJH@85004|Bifidobacteriales 201174|Actinobacteria T PhoH-like protein phoH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06217 - - - - ko00000 - - - PhoH BHPHKHDA_01181 326426.Bbr_0918 1.33e-133 378.0 COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CZJF@85004|Bifidobacteriales 201174|Actinobacteria S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 BHPHKHDA_01182 326426.Bbr_0919 0.0 884.0 COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CZ1W@85004|Bifidobacteriales 201174|Actinobacteria S CBS domain corC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - CBS,CorC_HlyC,DUF21 BHPHKHDA_01183 326426.Bbr_0920 9.08e-235 646.0 COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CYZH@85004|Bifidobacteriales 201174|Actinobacteria S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 BHPHKHDA_01184 326426.Bbr_0921 0.0 1335.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYJ@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme fadD2 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding BHPHKHDA_01185 326426.Bbr_0922 1.34e-260 716.0 COG3288@1|root,COG3288@2|Bacteria,2I2FZ@201174|Actinobacteria,4CZZ3@85004|Bifidobacteriales 201174|Actinobacteria C NAD(P) transhydrogenase subunit alpha part 1 K00324 pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM BHPHKHDA_01186 326426.Bbr_0923 3.42e-56 176.0 COG3288@1|root,COG3288@2|Bacteria,2IKR9@201174|Actinobacteria,4D12D@85004|Bifidobacteriales 201174|Actinobacteria C 4TM region of pyridine nucleotide transhydrogenase, mitoch pntAB - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM BHPHKHDA_01187 326426.Bbr_0924 8.58e-308 843.0 COG1282@1|root,COG1282@2|Bacteria,2GNKB@201174|Actinobacteria,4CZF5@85004|Bifidobacteriales 201174|Actinobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB BHPHKHDA_01188 326426.Bbr_0925 5.08e-299 816.0 COG0477@1|root,COG2814@2|Bacteria,2I2ID@201174|Actinobacteria,4CZX9@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 BHPHKHDA_01189 326426.Bbr_0926 1.08e-129 370.0 COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CZ7W@85004|Bifidobacteriales 201174|Actinobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C BHPHKHDA_01190 326426.Bbr_0927 2.72e-288 785.0 COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CZD9@85004|Bifidobacteriales 201174|Actinobacteria E Amino-transferase class IV ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 BHPHKHDA_01191 326426.Bbr_0928 2.95e-187 523.0 COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CZ9U@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 mazG GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0022607,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0035539,GO:0042454,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0047693,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 ko:K02428,ko:K02499 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000,ko03036 - - - MazG BHPHKHDA_01192 326426.Bbr_0929 4.82e-179 499.0 COG2860@1|root,COG2860@2|Bacteria,2GMI4@201174|Actinobacteria,4CZ51@85004|Bifidobacteriales 201174|Actinobacteria S UPF0126 domain - - - - - - - - - - - - UPF0126 BHPHKHDA_01193 326426.Bbr_0930 4.75e-47 151.0 COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D18U@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 16S ribosomal RNA rpsT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p BHPHKHDA_01194 326426.Bbr_0931 0.0 1239.0 COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CYWI@85004|Bifidobacteriales 201174|Actinobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C BHPHKHDA_01195 326426.Bbr_0932 0.0 874.0 COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CZ81@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - iNJ661.Rv2388c HemN_C,Radical_SAM BHPHKHDA_01197 326426.Bbr_0934 9.59e-245 672.0 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CZS8@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_01198 326426.Bbr_0936 0.0 3022.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2GN09@201174|Actinobacteria,4CZB8@85004|Bifidobacteriales 201174|Actinobacteria E glutamate synthase NADPH large subunit gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase BHPHKHDA_01199 326426.Bbr_0937 0.0 1049.0 COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,4CZ7B@85004|Bifidobacteriales 201174|Actinobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iNJ661.Rv3858c Fer4_20,Pyr_redox_2 BHPHKHDA_01201 326426.Bbr_0938 2.86e-58 181.0 2A95S@1|root,30YAB@2|Bacteria,2HBBF@201174|Actinobacteria,4D2NR@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01202 326426.Bbr_0939 0.0 1093.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 BHPHKHDA_01203 326426.Bbr_0940 0.0 1321.0 28J61@1|root,2Z91S@2|Bacteria,2HZIR@201174|Actinobacteria,4D0KC@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl hydrolases related to GH101 family, GH129 - - - - - - - - - - - - Glyco_hydro_129 BHPHKHDA_01204 216816.GS08_04765 2.41e-106 306.0 2BI32@1|root,32C84@2|Bacteria,2IDD6@201174|Actinobacteria,4D0PC@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - PsbJ BHPHKHDA_01205 326426.Bbr_0942 1.6e-310 845.0 COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4CZKY@85004|Bifidobacteriales 201174|Actinobacteria G Starch synthase catalytic domain glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 - R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 BHPHKHDA_01206 326426.Bbr_0943 4.18e-202 561.0 COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,4CZDS@85004|Bifidobacteriales 201174|Actinobacteria P ATPases associated with a variety of cellular activities ylmA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran BHPHKHDA_01207 216816.GS08_04780 3.18e-201 557.0 COG0561@1|root,COG0561@2|Bacteria,2GNWG@201174|Actinobacteria,4CZY9@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 BHPHKHDA_01208 326426.Bbr_0947 5.35e-122 349.0 COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4D0PN@85004|Bifidobacteriales 201174|Actinobacteria O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA BHPHKHDA_01209 326426.Bbr_0948 4.24e-182 508.0 2ARR4@1|root,31H25@2|Bacteria,2IG5G@201174|Actinobacteria,4D0U6@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01210 1693.BMIN_0226 1.89e-101 306.0 COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales 201174|Actinobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut BHPHKHDA_01213 326426.Bbr_0961 2.39e-227 625.0 COG0657@1|root,COG0657@2|Bacteria,2GNKU@201174|Actinobacteria,4CZVA@85004|Bifidobacteriales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 BHPHKHDA_01214 326426.Bbr_0962 1.93e-117 336.0 COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria,4D01A@85004|Bifidobacteriales 201174|Actinobacteria S Appr-1'-p processing enzyme lppD GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Macro BHPHKHDA_01215 326426.Bbr_0963 1.64e-186 517.0 COG4186@1|root,COG4186@2|Bacteria,2IRS9@201174|Actinobacteria,4D018@85004|Bifidobacteriales 201174|Actinobacteria S phosphoesterase or phosphohydrolase - - - - - - - - - - - - Metallophos,Metallophos_2 BHPHKHDA_01216 326426.Bbr_0964 4.16e-181 503.0 COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,4CZUI@85004|Bifidobacteriales 201174|Actinobacteria K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 BHPHKHDA_01218 326426.Bbr_0966 4.32e-172 479.0 COG0400@1|root,COG0400@2|Bacteria,2GNIF@201174|Actinobacteria,4D0TH@85004|Bifidobacteriales 201174|Actinobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 BHPHKHDA_01219 326426.Bbr_0967 9.33e-254 696.0 COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CYUG@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA trmI GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 ko:K07442 - - - - ko00000,ko01000,ko03016 - - - GCD14,GCD14_N BHPHKHDA_01220 326426.Bbr_0968 5.84e-129 366.0 COG2062@1|root,COG2062@2|Bacteria,2GJ0I@201174|Actinobacteria,4D05N@85004|Bifidobacteriales 201174|Actinobacteria T Phosphoglycerate mutase family sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 BHPHKHDA_01222 326426.Bbr_0969 0.0 1508.0 COG0620@1|root,COG0620@2|Bacteria,2GIXA@201174|Actinobacteria,4CYWM@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0040007,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 BHPHKHDA_01223 326426.Bbr_0970 2.74e-208 575.0 COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,4CZ22@85004|Bifidobacteriales 201174|Actinobacteria E Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR BHPHKHDA_01224 326426.Bbr_0971 3.45e-239 656.0 COG3049@1|root,COG3049@2|Bacteria,2GK9Z@201174|Actinobacteria,4CZNU@85004|Bifidobacteriales 201174|Actinobacteria M Linear amide C-N hydrolase, choloylglycine hydrolase family protein cbh - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH BHPHKHDA_01225 326426.Bbr_0972 0.0 2065.0 COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4CYQE@85004|Bifidobacteriales 201174|Actinobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE BHPHKHDA_01226 326426.Bbr_0973 8.56e-227 625.0 COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CYZR@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the ATCase OTCase family pyrB - 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N BHPHKHDA_01227 326426.Bbr_0974 2.61e-96 280.0 COG1781@1|root,COG1781@2|Bacteria,2IFDF@201174|Actinobacteria,4D0QN@85004|Bifidobacteriales 201174|Actinobacteria F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein pyrI - - ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002 - - - PyrI,PyrI_C BHPHKHDA_01228 326426.Bbr_0975 0.0 994.0 COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,4CZIW@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 BHPHKHDA_01229 326426.Bbr_0976 1.74e-223 616.0 COG0284@1|root,COG0284@2|Bacteria,2GKWK@201174|Actinobacteria,4CZAK@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the OMP decarboxylase family. Type 2 subfamily pyrF - 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase BHPHKHDA_01230 326426.Bbr_0977 2.25e-202 559.0 COG0543@1|root,COG0543@2|Bacteria,2HQ24@201174|Actinobacteria,4CZC1@85004|Bifidobacteriales 201174|Actinobacteria C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B pyrK - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 BHPHKHDA_01231 326426.Bbr_0978 6.9e-233 640.0 COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYU2@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD - 1.3.1.14 ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh BHPHKHDA_01232 326426.Bbr_0979 4.64e-160 449.0 COG0461@1|root,COG0461@2|Bacteria,2GM5A@201174|Actinobacteria,4CZHB@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran BHPHKHDA_01233 216816.GS08_04970 1.08e-39 131.0 2B3KJ@1|root,31W9X@2|Bacteria,2GWXF@201174|Actinobacteria,4D1NA@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01234 326426.Bbr_0980 4.99e-274 749.0 COG1073@1|root,COG1073@2|Bacteria,2GMT6@201174|Actinobacteria,4CZ4Q@85004|Bifidobacteriales 201174|Actinobacteria S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - DUF2974 BHPHKHDA_01235 326426.Bbr_0981 1.55e-221 610.0 COG0583@1|root,COG0583@2|Bacteria,2HZCU@201174|Actinobacteria,4CZT8@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory helix-turn-helix protein, lysR family - - - - - - - - - - - - HTH_1,LysR_substrate BHPHKHDA_01236 326426.Bbr_0982 1.93e-157 440.0 COG1011@1|root,COG1011@2|Bacteria,2I8XE@201174|Actinobacteria,4D00B@85004|Bifidobacteriales 201174|Actinobacteria S Haloacid dehalogenase-like hydrolase - - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 BHPHKHDA_01237 326426.Bbr_0983 0.0 1111.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CZC5@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N BHPHKHDA_01238 326426.Bbr_0984 0.0 1033.0 COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4CYS2@85004|Bifidobacteriales 201174|Actinobacteria S ABC transporter ybiT - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_Xtn,DLIC BHPHKHDA_01239 326426.Bbr_0985 5.24e-168 469.0 COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria,4CZA7@85004|Bifidobacteriales 201174|Actinobacteria S Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short BHPHKHDA_01240 1437610.BREU_0058 1.66e-25 106.0 COG1129@1|root,COG1129@2|Bacteria,2I2G1@201174|Actinobacteria,4CZ58@85004|Bifidobacteriales 201174|Actinobacteria G ATPases associated with a variety of cellular activities - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran BHPHKHDA_01241 1437610.BREU_0056 4.45e-120 347.0 2BY0N@1|root,321KG@2|Bacteria,2IEYW@201174|Actinobacteria,4CZZD@85004|Bifidobacteriales 201174|Actinobacteria S Hypothetical bacterial integral membrane protein (Trep_Strep) - - - ko:K16926 - M00582 - - ko00000,ko00002,ko02000 3.A.1.31 - - Trep_Strep BHPHKHDA_01242 326426.Bbr_0988 1.67e-295 805.0 COG0436@1|root,COG0436@2|Bacteria,2GPM3@201174|Actinobacteria,4CZ6T@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - 2.6.1.1 ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 BHPHKHDA_01243 326426.Bbr_0989 0.0 2011.0 COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CYRU@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran BHPHKHDA_01244 326426.Bbr_0990 0.0 1540.0 COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CYVX@85004|Bifidobacteriales 201174|Actinobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N BHPHKHDA_01245 326426.Bbr_0991 2.95e-240 659.0 COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CZCM@85004|Bifidobacteriales 201174|Actinobacteria E Shikimate dehydrogenase substrate binding domain aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv2552c Shikimate_DH,Shikimate_dh_N BHPHKHDA_01246 326426.Bbr_0992 5.43e-229 630.0 COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CZ70@85004|Bifidobacteriales 201174|Actinobacteria S Displays ATPase and GTPase activities yvcJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 BHPHKHDA_01247 326426.Bbr_0993 2.86e-217 600.0 COG1481@1|root,COG1481@2|Bacteria,2GJZU@201174|Actinobacteria,4CYTD@85004|Bifidobacteriales 201174|Actinobacteria K May be required for sporulation whiA GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0043937,GO:0044464,GO:0050789,GO:0050793,GO:0065007,GO:0071944 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N BHPHKHDA_01248 216816.GS08_05570 2.06e-278 762.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CZJ3@85004|Bifidobacteriales 201174|Actinobacteria F Phosphoglycerate kinase pgk GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.7.2.3,5.3.1.1 ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01015,R01512 RC00002,RC00043,RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK BHPHKHDA_01249 326426.Bbr_0995 4.88e-188 523.0 COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CYSG@85004|Bifidobacteriales 201174|Actinobacteria G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM BHPHKHDA_01250 326426.Bbr_0996 5.94e-46 148.0 COG1314@1|root,COG1314@2|Bacteria,2GR31@201174|Actinobacteria,4D16U@85004|Bifidobacteriales 201174|Actinobacteria U Preprotein translocase SecG subunit secG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG BHPHKHDA_01251 326426.Bbr_0997 4.61e-223 615.0 COG0039@1|root,COG0039@2|Bacteria,2IASS@201174|Actinobacteria,4CZRT@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the LDH MDH superfamily ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N BHPHKHDA_01252 326426.Bbr_0998 2e-205 568.0 COG0561@1|root,COG0561@2|Bacteria,2HZYB@201174|Actinobacteria,4CZQW@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 BHPHKHDA_01253 326426.Bbr_0999 0.0 1028.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZVJ@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase, class I II aspC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iNJ661.Rv0337c Aminotran_1_2 BHPHKHDA_01254 326426.Bbr_1000 1.61e-244 676.0 29VGS@1|root,30GYC@2|Bacteria,2GXVQ@201174|Actinobacteria,4D1QB@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01255 326426.Bbr_1001 3.42e-297 813.0 COG1114@1|root,COG1114@2|Bacteria,2GNMD@201174|Actinobacteria,4CZIP@85004|Bifidobacteriales 201174|Actinobacteria U Component of the transport system for branched-chain amino acids brnQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans BHPHKHDA_01256 216816.GS08_05525 2.71e-259 711.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 201174|Actinobacteria H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA BHPHKHDA_01257 326426.Bbr_1003 0.0 1409.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the transketolase family tkt GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N BHPHKHDA_01258 326426.Bbr_1004 4.92e-245 675.0 COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CZK3@85004|Bifidobacteriales 201174|Actinobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HTH_DeoR,HrcA BHPHKHDA_01259 326426.Bbr_1005 2.29e-274 750.0 COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4D03K@85004|Bifidobacteriales 201174|Actinobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG BHPHKHDA_01260 326426.Bbr_1006 7.54e-200 552.0 COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria,4CZ4W@85004|Bifidobacteriales 201174|Actinobacteria G Fructosamine kinase - - - - - - - - - - - - Fructosamin_kin BHPHKHDA_01261 326426.Bbr_1007 1.51e-201 559.0 COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CZ83@85004|Bifidobacteriales 201174|Actinobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA BHPHKHDA_01262 216816.GS08_05495 1.78e-168 473.0 COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4CYSJ@85004|Bifidobacteriales 201174|Actinobacteria S PAC2 family - - - - - - - - - - - - PAC2 BHPHKHDA_01268 326426.Bbr_1009 0.0 1362.0 COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4CZD3@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD BHPHKHDA_01269 326426.Bbr_1010 1.6e-144 406.0 COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CZS7@85004|Bifidobacteriales 201174|Actinobacteria FG HIT domain - GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 ko:K19710 ko00230,map00230 - R00126,R01618 RC00002,RC02753,RC02795 ko00000,ko00001,ko01000 - - - HIT BHPHKHDA_01270 326426.Bbr_1011 1.19e-156 442.0 COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CZ9X@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg BHPHKHDA_01271 326426.Bbr_1012 4.21e-131 372.0 COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,4CZ79@85004|Bifidobacteriales 201174|Actinobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC BHPHKHDA_01272 326426.Bbr_1013 1.19e-137 390.0 COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CZCE@85004|Bifidobacteriales 201174|Actinobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N BHPHKHDA_01273 326426.Bbr_1014 2.9e-252 692.0 COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CZGU@85004|Bifidobacteriales 201174|Actinobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N BHPHKHDA_01274 326426.Bbr_1015 6.21e-72 219.0 COG1862@1|root,COG1862@2|Bacteria,2IKUJ@201174|Actinobacteria,4D139@85004|Bifidobacteriales 201174|Actinobacteria U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC BHPHKHDA_01275 326426.Bbr_1016 1.86e-129 368.0 COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria,4CZ9H@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran BHPHKHDA_01276 326426.Bbr_1017 4.18e-282 771.0 COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CZCQ@85004|Bifidobacteriales 201174|Actinobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA BHPHKHDA_01277 326426.Bbr_1018 5.31e-211 583.0 COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CYX1@85004|Bifidobacteriales 201174|Actinobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA BHPHKHDA_01278 326426.Bbr_1019 2.3e-295 810.0 2EKVE@1|root,33EIZ@2|Bacteria,2HZ8H@201174|Actinobacteria,4CYRN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01279 326426.Bbr_1020 0.0 1068.0 COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CZ3P@85004|Bifidobacteriales 201174|Actinobacteria F Bifunctional purine biosynthesis protein PurH purH GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS BHPHKHDA_01280 762211.BSTEL_0211 3.55e-43 142.0 2AXAE@1|root,31P9H@2|Bacteria,2IQKC@201174|Actinobacteria,4D18B@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF3017 BHPHKHDA_01281 326426.Bbr_1021 2.36e-175 494.0 COG0580@1|root,COG0580@2|Bacteria,2HZ9W@201174|Actinobacteria,4CZ5Q@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the MIP aquaporin (TC 1.A.8) family - - - ko:K06188 - - - - ko00000,ko02000 1.A.8 - - MIP BHPHKHDA_01282 326426.Bbr_1022 9.06e-184 511.0 COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4CZGG@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the pseudouridine synthase RsuA family rluB GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 BHPHKHDA_01283 326426.Bbr_1023 0.0 1363.0 COG0283@1|root,COG1160@1|root,COG0283@2|Bacteria,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,4CYSE@85004|Bifidobacteriales 201174|Actinobacteria F GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K03977 - - - - ko00000,ko03009 - - - Cytidylate_kin,KH_dom-like,MMR_HSR1 BHPHKHDA_01285 326426.Bbr_1024 8.84e-207 571.0 COG0561@1|root,COG0561@2|Bacteria,2HZBZ@201174|Actinobacteria,4CZNM@85004|Bifidobacteriales 201174|Actinobacteria S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 BHPHKHDA_01286 326426.Bbr_1025 0.0 1005.0 COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4CYTQ@85004|Bifidobacteriales 201174|Actinobacteria G UTP-glucose-1-phosphate uridylyltransferase ugp - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - UDPGP BHPHKHDA_01287 326426.Bbr_1026 0.0 1229.0 COG2378@1|root,COG2378@2|Bacteria,2I8M5@201174|Actinobacteria,4CZWF@85004|Bifidobacteriales 201174|Actinobacteria K WYL domain - - - - - - - - - - - - WYL BHPHKHDA_01288 326426.Bbr_1027 4.22e-70 211.0 2B5BE@1|root,31Y5K@2|Bacteria,2IQT5@201174|Actinobacteria,4D17A@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01289 326426.Bbr_1028 0.0 1695.0 COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,4CZEC@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase helY GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K03727 - - - - ko00000,ko01000 - - - DEAD,DSHCT,Helicase_C,rRNA_proc-arch BHPHKHDA_01290 326426.Bbr_1029 3.18e-81 240.0 2CNY9@1|root,32SI2@2|Bacteria,2IMK6@201174|Actinobacteria,4D0V5@85004|Bifidobacteriales 201174|Actinobacteria K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters rbpA GO:0001000,GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0043167,GO:0043169,GO:0043175,GO:0045893,GO:0045935,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - - - - - - - - - - RbpA BHPHKHDA_01291 326426.Bbr_1030 6.16e-178 494.0 COG0546@1|root,COG0546@2|Bacteria,2HFGX@201174|Actinobacteria,4CYSF@85004|Bifidobacteriales 201174|Actinobacteria S HAD-hyrolase-like nt5e GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0071704,GO:0140096,GO:1901564 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 BHPHKHDA_01292 326426.Bbr_1031 1.21e-48 154.0 2BB9R@1|root,324SH@2|Bacteria,2H9QN@201174|Actinobacteria,4D2DN@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01293 326426.Bbr_1032 3.89e-87 256.0 29TZI@1|root,30F8H@2|Bacteria,2ISJH@201174|Actinobacteria,4D0Z6@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01294 326426.Bbr_1033 2.6e-142 402.0 COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,4CZ0X@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, mercury resistance merR2 - - - - - - - - - - - MerR_1 BHPHKHDA_01295 326426.Bbr_1034 2.02e-97 283.0 COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4D0R3@85004|Bifidobacteriales 201174|Actinobacteria T Inner membrane component of T3SS, cytoplasmic domain garA GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - - - - - - - - - - FHA,Yop-YscD_cpl,zinc_ribbon_2 BHPHKHDA_01296 326426.Bbr_1035 6.51e-181 505.0 COG3879@1|root,COG3879@2|Bacteria,2GJ3C@201174|Actinobacteria,4CYYH@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 BHPHKHDA_01297 326426.Bbr_1036 6.08e-61 188.0 COG3856@1|root,COG3856@2|Bacteria,2IKJW@201174|Actinobacteria,4D12G@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF1290) sbp - - - - - - - - - - - DUF1290 BHPHKHDA_01298 326426.Bbr_1037 4.04e-217 601.0 COG3879@1|root,COG3879@2|Bacteria,2GMS5@201174|Actinobacteria,4CZ72@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 BHPHKHDA_01299 326426.Bbr_1038 3.69e-135 384.0 COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4CZGD@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA2 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf BHPHKHDA_01300 326426.Bbr_1039 3.56e-199 552.0 COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CZ66@85004|Bifidobacteriales 201174|Actinobacteria F ATP phosphoribosyltransferase hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,HisG_C BHPHKHDA_01301 326426.Bbr_1040 5.07e-56 174.0 COG0140@1|root,COG0140@2|Bacteria,2IQ4D@201174|Actinobacteria,4D108@85004|Bifidobacteriales 201174|Actinobacteria E Phosphoribosyl-ATP pyrophosphohydrolase hisE GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0044403,GO:0044419,GO:0044464,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0071944,GO:0075136,GO:0075139 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH BHPHKHDA_01302 326426.Bbr_1041 7.16e-155 435.0 COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4CYX0@85004|Bifidobacteriales 201174|Actinobacteria G Ribulose-phosphate 3-epimerase rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim BHPHKHDA_01303 326426.Bbr_1042 1.11e-239 657.0 COG0682@1|root,COG0682@2|Bacteria,2GKSS@201174|Actinobacteria,4CYV8@85004|Bifidobacteriales 201174|Actinobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - LGT BHPHKHDA_01304 326426.Bbr_1043 1.03e-206 572.0 COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,4D0A3@85004|Bifidobacteriales 201174|Actinobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA BHPHKHDA_01305 326426.Bbr_1044 0.0 1345.0 COG0133@1|root,COG0134@1|root,COG0133@2|Bacteria,COG0134@2|Bacteria,2GM7Z@201174|Actinobacteria,4CZJW@85004|Bifidobacteriales 201174|Actinobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - IGPS,PALP BHPHKHDA_01306 326426.Bbr_1045 1.84e-170 475.0 COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CZPW@85004|Bifidobacteriales 201174|Actinobacteria S SOS response associated peptidase (SRAP) - - - - - - - - - - - - SRAP BHPHKHDA_01307 216816.GS08_05280 4.15e-196 544.0 COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,4CZ0H@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 BHPHKHDA_01308 326426.Bbr_1047 0.0 896.0 COG0833@1|root,COG0833@2|Bacteria,2I2DX@201174|Actinobacteria,4D2V7@85004|Bifidobacteriales 201174|Actinobacteria E amino acid - - - ko:K16235 - - - - ko00000,ko02000 2.A.3.1.10 - - AA_permease BHPHKHDA_01310 326426.Bbr_1049 6.97e-240 659.0 COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria,4CZBZ@85004|Bifidobacteriales 201174|Actinobacteria V VanZ like family - - - - - - - - - - - - RDD,VanZ BHPHKHDA_01311 1343740.M271_39675 2.85e-18 85.1 COG0520@1|root,COG0520@2|Bacteria,2GNM2@201174|Actinobacteria 201174|Actinobacteria E Aminotransferase, class V cefD - 5.1.1.17 ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 M00673 R04147 RC00302 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 BHPHKHDA_01312 749414.SBI_00921 5e-42 151.0 COG0520@1|root,COG0520@2|Bacteria,2GNM2@201174|Actinobacteria 201174|Actinobacteria E Aminotransferase, class V cefD - 5.1.1.17 ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 M00673 R04147 RC00302 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_5 BHPHKHDA_01313 326426.Bbr_1054 3.57e-35 119.0 COG4367@1|root,COG4367@2|Bacteria,2IPTA@201174|Actinobacteria,4D10S@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized protein conserved in bacteria (DUF2316) - - - - - - - - - - - - DUF2316 BHPHKHDA_01314 216816.GS08_05230 1.1e-129 367.0 COG3981@1|root,COG3981@2|Bacteria,2HEQC@201174|Actinobacteria,4D0EK@85004|Bifidobacteriales 201174|Actinobacteria S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 BHPHKHDA_01315 216816.GS08_05175 3.88e-62 202.0 COG0577@1|root,COG0577@2|Bacteria,2HXTZ@201174|Actinobacteria,4CZYZ@85004|Bifidobacteriales 201174|Actinobacteria V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BHPHKHDA_01316 326426.Bbr_1066 1.49e-53 168.0 COG3077@1|root,COG3077@2|Bacteria,2GV25@201174|Actinobacteria,4D179@85004|Bifidobacteriales 201174|Actinobacteria L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB BHPHKHDA_01317 326426.Bbr_1067 2.55e-65 198.0 COG3041@1|root,COG3041@2|Bacteria,2GSX9@201174|Actinobacteria,4D1AZ@85004|Bifidobacteriales 201174|Actinobacteria S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin BHPHKHDA_01319 326426.Bbr_0418 1.16e-42 148.0 COG1175@1|root,COG1175@2|Bacteria,2GMTW@201174|Actinobacteria,4CZX2@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_01320 326426.Bbr_0420 0.0 1460.0 COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ38@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 bga1 - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M BHPHKHDA_01321 326426.Bbr_0421 1.66e-245 675.0 COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D040@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_01322 326426.Bbr_0424 1.47e-210 581.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales 201174|Actinobacteria S Oxidoreductase, aldo keto reductase family protein - - - - - - - - - - - - Aldo_ket_red BHPHKHDA_01323 326426.Bbr_0425 7.45e-181 503.0 COG2356@1|root,COG2356@2|Bacteria,2GJ38@201174|Actinobacteria,4CZCY@85004|Bifidobacteriales 201174|Actinobacteria L Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524 BHPHKHDA_01324 216816.GS08_02195 2.77e-189 533.0 COG1373@1|root,COG1373@2|Bacteria,2HYYJ@201174|Actinobacteria,4D0C8@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - - - - - - - - - - AAA_14,DUF4143 BHPHKHDA_01325 326426.Bbr_0427 2.25e-300 821.0 COG1914@1|root,COG1914@2|Bacteria,2GJSM@201174|Actinobacteria,4CZZB@85004|Bifidobacteriales 201174|Actinobacteria P H( )-stimulated, divalent metal cation uptake system mntH GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0030001,GO:0034220,GO:0034755,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071421,GO:0071577,GO:0071578,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587 - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp BHPHKHDA_01326 326426.Bbr_0428 0.0 972.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales 201174|Actinobacteria U Drug resistance MFS transporter, drug H antiporter-2 family - - - - - - - - - - - - MFS_1 BHPHKHDA_01327 326426.Bbr_0429 0.0 1150.0 COG2959@1|root,COG2959@2|Bacteria,2I2HI@201174|Actinobacteria,4CYVN@85004|Bifidobacteriales 201174|Actinobacteria H Protein of unknown function (DUF4012) - - - - - - - - - - - - DUF4012 BHPHKHDA_01328 326426.Bbr_0430 0.0 1069.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4CZ4J@85004|Bifidobacteriales 201174|Actinobacteria M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase rfbP - - - - - - - - - - - Bac_transf,CoA_binding_3 BHPHKHDA_01329 326426.Bbr_0431 8.82e-141 397.0 COG0394@1|root,COG0394@2|Bacteria,2GMPR@201174|Actinobacteria,4D0GD@85004|Bifidobacteriales 201174|Actinobacteria T Low molecular weight phosphatase family etp - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc BHPHKHDA_01330 398513.BBNG_00001 1.38e-47 159.0 COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D1MQ@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives IS30 family - - - - - - - - - - - - HTH_38,rve BHPHKHDA_01331 518635.BIFANG_03640 5.54e-127 369.0 COG1442@1|root,COG1442@2|Bacteria,2HFT7@201174|Actinobacteria,4CZBS@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF4422) - - - - - - - - - - - - DUF4422 BHPHKHDA_01332 1435051.BMOU_1534 6.43e-284 775.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 201174|Actinobacteria M UDP-galactopyranose mutase glf GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - iNJ661.Rv3809c GLF,NAD_binding_8 BHPHKHDA_01333 77635.BISU_2463 2.78e-34 127.0 COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZQK@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_Tnp_1,rve,rve_3 BHPHKHDA_01334 78346.BRUM_0814 9.92e-91 268.0 COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales 201174|Actinobacteria L IstB-like ATP binding protein istB - - - - - - - - - - - IstB_IS21 BHPHKHDA_01335 78346.BRUM_1717 2.08e-75 232.0 COG1484@1|root,COG1484@2|Bacteria,2I90G@201174|Actinobacteria,4D05J@85004|Bifidobacteriales 201174|Actinobacteria L IstB-like ATP binding protein - - - - - - - - - - - - IstB_IS21 BHPHKHDA_01336 1437610.BREU_1989 1.93e-210 620.0 COG1373@1|root,COG3420@1|root,COG1373@2|Bacteria,COG3420@2|Bacteria,2GK1Q@201174|Actinobacteria,4D0A9@85004|Bifidobacteriales 201174|Actinobacteria P Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143,TIR_2 BHPHKHDA_01338 566552.BIFCAT_01197 3.34e-30 116.0 COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_21,rve BHPHKHDA_01339 78345.BMERY_1180 5.55e-169 473.0 COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales 201174|Actinobacteria L IstB-like ATP binding protein istB - - - - - - - - - - - IstB_IS21 BHPHKHDA_01340 702459.BBPR_0057 2.43e-263 730.0 COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4D0D7@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - rve BHPHKHDA_01341 78346.BRUM_1848 2.38e-84 257.0 COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_21,HTH_28,rve,rve_2 BHPHKHDA_01342 78346.BRUM_1693 3.45e-127 376.0 COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria,4D0H8@85004|Bifidobacteriales 201174|Actinobacteria K Transposase IS116 IS110 IS902 - - - - - - - - - - - - DEDD_Tnp_IS110,HTH_3,HTH_31,Transposase_20 BHPHKHDA_01343 1105029.HMPREF1137_0293 2.59e-25 118.0 COG4637@1|root,COG4637@2|Bacteria,2HMKR@201174|Actinobacteria,4D784@85005|Actinomycetales 201174|Actinobacteria S AAA ATPase domain - - - - - - - - - - - - AAA_15 BHPHKHDA_01344 1437610.BREU_1226 3.9e-110 330.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D0ME@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 BHPHKHDA_01345 1680.BADO_1353 1.98e-59 194.0 COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D023@85004|Bifidobacteriales 201174|Actinobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut BHPHKHDA_01346 78344.BIGA_1604 4.55e-86 258.0 2CM5B@1|root,32SDR@2|Bacteria,2IRBQ@201174|Actinobacteria,4D2GK@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01347 78344.BIGA_1603 3.37e-109 322.0 2BTX1@1|root,32P53@2|Bacteria,2GTTM@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01348 1680.BADO_1069 9.99e-92 272.0 COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_23,HTH_28 BHPHKHDA_01349 326426.Bbr_0116 0.0 1473.0 COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4CZ0F@85004|Bifidobacteriales 201174|Actinobacteria G 4-alpha-glucanotransferase malQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 BHPHKHDA_01350 326426.Bbr_0115 1.6e-220 609.0 COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase BHPHKHDA_01351 326426.Bbr_0114 0.0 1106.0 COG4932@1|root,COG4932@2|Bacteria,2IMAM@201174|Actinobacteria,4D140@85004|Bifidobacteriales 201174|Actinobacteria M domain protein - - - - - - - - - - - - GramPos_pilinBB,Gram_pos_anchor BHPHKHDA_01352 326426.Bbr_0113 0.0 2855.0 COG4932@1|root,COG4932@2|Bacteria,2HH2U@201174|Actinobacteria,4CZ5N@85004|Bifidobacteriales 201174|Actinobacteria M cell wall anchor domain protein - - - - - - - - - - - - Big_2,Gram_pos_anchor BHPHKHDA_01354 326426.Bbr_0112 1.84e-238 656.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_01355 216816.GS08_00585 0.0 1247.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZ1E@85004|Bifidobacteriales 201174|Actinobacteria G Alpha-amylase domain - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459 BHPHKHDA_01356 326426.Bbr_0846 1.53e-307 837.0 COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CZKB@85004|Bifidobacteriales 201174|Actinobacteria G Amidohydrolase family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 BHPHKHDA_01357 326426.Bbr_0847 1.01e-187 522.0 COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4CYYE@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso BHPHKHDA_01358 326426.Bbr_0848 8.22e-221 610.0 COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria,4CZII@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK BHPHKHDA_01359 326426.Bbr_0849 6.89e-278 760.0 COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4CZUF@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - Crp,HTH_24,ROK BHPHKHDA_01360 326426.Bbr_0850 1.12e-203 563.0 COG0676@1|root,COG0676@2|Bacteria,2IIUH@201174|Actinobacteria,4CZWN@85004|Bifidobacteriales 201174|Actinobacteria G Aldose 1-epimerase - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim BHPHKHDA_01361 326426.Bbr_0851 0.0 901.0 COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4D2XP@85004|Bifidobacteriales 201174|Actinobacteria U Sugar (and other) transporter gtr - - ko:K08139 ko04113,map04113 - - - ko00000,ko00001,ko02000 2.A.1.1 - - Sugar_tr BHPHKHDA_01362 326426.Bbr_0852 0.0 1069.0 COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4D246@85004|Bifidobacteriales 201174|Actinobacteria P Domain of unknown function (DUF4976) - - - - - - - - - - - - DUF4976,Sulfatase BHPHKHDA_01363 326426.Bbr_0853 0.0 931.0 COG0641@1|root,COG0641@2|Bacteria,2HZTM@201174|Actinobacteria,4D1Q0@85004|Bifidobacteriales 201174|Actinobacteria C Iron-sulfur cluster-binding domain - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM BHPHKHDA_01364 326426.Bbr_0854 7.98e-151 428.0 COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4D23D@85004|Bifidobacteriales 201174|Actinobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE BHPHKHDA_01365 326426.Bbr_0855 5.31e-70 212.0 COG2963@1|root,COG2963@2|Bacteria,2IF4K@201174|Actinobacteria,4D0JP@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_23,HTH_28 BHPHKHDA_01366 702459.BBPR_1620 9.29e-67 202.0 COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives IS30 family - - - - - - - - - - - - HTH_38,rve BHPHKHDA_01367 326426.Bbr_0312 2.48e-276 759.0 COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4D01G@85004|Bifidobacteriales 201174|Actinobacteria L Transposase, Mutator family - - - - - - - - - - - - Transposase_mut BHPHKHDA_01368 518635.BIFANG_02205 2.01e-68 207.0 COG3657@1|root,COG3657@2|Bacteria,2IRSY@201174|Actinobacteria,4D1CG@85004|Bifidobacteriales 201174|Actinobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 BHPHKHDA_01369 518635.BIFANG_02206 2.66e-58 181.0 COG3636@1|root,COG3636@2|Bacteria,2IRAI@201174|Actinobacteria,4D1DK@85004|Bifidobacteriales 201174|Actinobacteria K Addiction module - - - - - - - - - - - - - BHPHKHDA_01371 216816.GS08_00195 2.16e-103 305.0 COG3409@1|root,COG3409@2|Bacteria,2GMEN@201174|Actinobacteria,4D1HF@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF1906) - - - - - - - - - - - - DUF1906,PG_binding_1 BHPHKHDA_01372 864069.MicloDRAFT_00031430 1.3e-183 540.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,1JSFR@119045|Methylobacteriaceae 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K02032,ko:K13892 ko02010,ko02024,map02010,map02024 M00239,M00348 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.11 - - ABC_tran,oligo_HPY BHPHKHDA_01373 272562.CA_C3181 7e-121 355.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae 186801|Clostridia EP PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N,RCC1_2 BHPHKHDA_01374 1195236.CTER_2894 3.84e-156 446.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia 186801|Clostridia P PFAM binding-protein-dependent transport systems inner membrane component appB - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 BHPHKHDA_01375 86416.Clopa_1034 7.88e-239 676.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,36EUU@31979|Clostridiaceae 186801|Clostridia E family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 BHPHKHDA_01376 547043.BIFPSEUDO_04261 7.29e-26 105.0 COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,2GKD2@201174|Actinobacteria,4CZ6G@85004|Bifidobacteriales 201174|Actinobacteria C Thioredoxin domain - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin_3 BHPHKHDA_01377 566552.BIFCAT_01407 1.6e-83 264.0 COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,2GKD2@201174|Actinobacteria,4CZ6G@85004|Bifidobacteriales 201174|Actinobacteria C Thioredoxin domain - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin_3 BHPHKHDA_01379 326426.Bbr_0118 8.06e-298 812.0 COG2182@1|root,COG2182@2|Bacteria,2GJ8S@201174|Actinobacteria,4CZ8G@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein malE - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_01380 326426.Bbr_0119 0.0 910.0 COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4CYZ8@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component malC - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 BHPHKHDA_01381 326426.Bbr_0120 1.84e-206 572.0 COG3833@1|root,COG3833@2|Bacteria,2I2EZ@201174|Actinobacteria,4CZDE@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 BHPHKHDA_01382 1437610.BREU_0347 0.0 1280.0 COG1523@1|root,COG1523@2|Bacteria,2I2GM@201174|Actinobacteria,4CYSS@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 13 family apuB - 3.2.1.41,3.2.1.68 ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,CW_binding_1,DUF3372,PUD BHPHKHDA_01383 1437610.BREU_0348 7.29e-220 608.0 COG1011@1|root,COG1011@2|Bacteria,2I2GN@201174|Actinobacteria,4CZF4@85004|Bifidobacteriales 201174|Actinobacteria S HAD-hyrolase-like - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase BHPHKHDA_01384 1437610.BREU_0349 3.27e-187 520.0 2AYHW@1|root,32WBP@2|Bacteria,2I9DQ@201174|Actinobacteria,4CYRI@85004|Bifidobacteriales 201174|Actinobacteria S TraX protein traX - - - - - - - - - - - TraX BHPHKHDA_01385 326426.Bbr_0122 5.58e-248 680.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_01386 216816.GS08_07340 3.71e-37 130.0 COG2826@1|root,COG2826@2|Bacteria,2H4CW@201174|Actinobacteria,4D25Y@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_38 BHPHKHDA_01387 518635.BIFANG_03650 3.31e-228 635.0 COG1143@1|root,COG1143@2|Bacteria,2I42G@201174|Actinobacteria,4D2WE@85004|Bifidobacteriales 201174|Actinobacteria C Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans BHPHKHDA_01388 518635.BIFANG_03649 2.87e-166 474.0 COG1215@1|root,COG1215@2|Bacteria,2IPTK@201174|Actinobacteria,4D12W@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - ko:K19427 - - - - ko00000,ko01000 - GT2 - Glycos_transf_2 BHPHKHDA_01389 518635.BIFANG_03648 9.15e-188 528.0 COG0778@1|root,COG0778@2|Bacteria,2IE9H@201174|Actinobacteria,4CZI3@85004|Bifidobacteriales 201174|Actinobacteria C Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Nitroreductase BHPHKHDA_01390 518635.BIFANG_03647 1.28e-219 609.0 COG0438@1|root,COG0438@2|Bacteria,2IEFR@201174|Actinobacteria,4CZQH@85004|Bifidobacteriales 201174|Actinobacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - BHPHKHDA_01391 518635.BIFANG_03646 4.18e-280 773.0 COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C BHPHKHDA_01393 518635.BIFANG_03644 3.36e-196 548.0 COG1216@1|root,COG1216@2|Bacteria,2I2EQ@201174|Actinobacteria,4CZNW@85004|Bifidobacteriales 201174|Actinobacteria S Glycosyl transferase family 2 - - 2.7.8.12 ko:K09809 - - - - ko00000,ko01000 - - - Glycos_transf_2 BHPHKHDA_01394 547043.BIFPSEUDO_03313 6.16e-33 122.0 COG1442@1|root,COG1442@2|Bacteria,2HFT7@201174|Actinobacteria,4CZBS@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF4422) - - - - - - - - - - - - DUF4422 BHPHKHDA_01400 1680.BADO_1364 9e-48 164.0 COG1106@1|root,COG1106@2|Bacteria,2GMVX@201174|Actinobacteria,4CZWP@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K06926 - - - - ko00000 - - - AAA_21 BHPHKHDA_01401 1680.BADO_1364 6.02e-37 136.0 COG1106@1|root,COG1106@2|Bacteria,2GMVX@201174|Actinobacteria,4CZWP@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K06926 - - - - ko00000 - - - AAA_21 BHPHKHDA_01402 1680.BADO_1070 5.82e-133 379.0 COG2801@1|root,COG2801@2|Bacteria,2H928@201174|Actinobacteria,4CZCP@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 BHPHKHDA_01403 591157.SSLG_00641 2.48e-16 77.8 2EPJ6@1|root,33H5U@2|Bacteria,2IT42@201174|Actinobacteria 201174|Actinobacteria S Unextendable partial coding region - - - - - - - - - - - - - BHPHKHDA_01405 1437610.BREU_0351 0.0 3249.0 COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4D2UY@85004|Bifidobacteriales 201174|Actinobacteria M Aamy_C - - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,Big_4,CBM_25,CBM_48,DUF5011,PUD BHPHKHDA_01406 326426.Bbr_0124 0.0 1144.0 COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CZDX@85004|Bifidobacteriales 201174|Actinobacteria O Heat shock 70 kDa protein dnaK GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 BHPHKHDA_01407 326426.Bbr_0125 2.49e-114 333.0 COG0576@1|root,COG0576@2|Bacteria,2GP4F@201174|Actinobacteria,4CZJ6@85004|Bifidobacteriales 201174|Actinobacteria O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE BHPHKHDA_01408 326426.Bbr_0126 2.45e-224 620.0 COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CZ68@85004|Bifidobacteriales 201174|Actinobacteria O DnaJ molecular chaperone homology domain dnaJ GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG BHPHKHDA_01409 326426.Bbr_0127 2.35e-133 378.0 COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4D0Q7@85004|Bifidobacteriales 201174|Actinobacteria K transcriptional regulator, MerR family hspR GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 BHPHKHDA_01410 1437610.BREU_1929 5.43e-21 91.3 COG2233@1|root,COG2233@2|Bacteria,2GV9H@201174|Actinobacteria,4CZYX@85004|Bifidobacteriales 201174|Actinobacteria F Psort location CytoplasmicMembrane, score 10.00 - - - - - - - - - - - - Xan_ur_permease BHPHKHDA_01411 1437610.BREU_1927 1.1e-141 414.0 COG1012@1|root,COG1012@2|Bacteria,2HZAQ@201174|Actinobacteria,4CZDA@85004|Bifidobacteriales 201174|Actinobacteria C Acyl-CoA reductase (LuxC) - - - - - - - - - - - - LuxC BHPHKHDA_01412 326426.Bbr_0129 7.57e-180 501.0 COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4D0FH@85004|Bifidobacteriales 201174|Actinobacteria IQ Oxidoreductase, short chain dehydrogenase reductase family protein - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 BHPHKHDA_01413 326426.Bbr_0130 1.57e-163 457.0 COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria,4CYZV@85004|Bifidobacteriales 201174|Actinobacteria S HAD hydrolase, family IA, variant 3 - - - - - - - - - - - - HAD_2 BHPHKHDA_01414 326426.Bbr_0131 7.43e-171 477.0 COG0586@1|root,COG0586@2|Bacteria,2GKGR@201174|Actinobacteria,4CZ7Y@85004|Bifidobacteriales 201174|Actinobacteria S SNARE associated Golgi protein dedA1 - - ko:K03975 - - - - ko00000 - - - SNARE_assoc BHPHKHDA_01415 326426.Bbr_0132 1.69e-155 439.0 COG0455@1|root,COG0455@2|Bacteria,2HZIH@201174|Actinobacteria,4D0JG@85004|Bifidobacteriales 201174|Actinobacteria D bacterial-type flagellum organization - - - - - - - - - - - - ParA BHPHKHDA_01416 326426.Bbr_0133 2.43e-241 663.0 COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CZF2@85004|Bifidobacteriales 201174|Actinobacteria U Type II IV secretion system protein cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE BHPHKHDA_01417 326426.Bbr_0134 1.2e-93 277.0 COG4965@1|root,COG4965@2|Bacteria,2GRXU@201174|Actinobacteria,4D1A3@85004|Bifidobacteriales 201174|Actinobacteria U Type ii secretion system - - - ko:K12510 - - - - ko00000,ko02044 - - - - BHPHKHDA_01418 326426.Bbr_0135 3.27e-149 420.0 COG2064@1|root,COG2064@2|Bacteria,2I2FP@201174|Actinobacteria,4D16W@85004|Bifidobacteriales 201174|Actinobacteria NU Type II secretion system (T2SS), protein F - - - - - - - - - - - - T2SSF BHPHKHDA_01419 326426.Bbr_0136 3.68e-55 172.0 2EHCF@1|root,33B4A@2|Bacteria,2GR72@201174|Actinobacteria,4D1FR@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4244) - - - - - - - - - - - - DUF4244 BHPHKHDA_01420 326426.Bbr_0137 2.92e-75 226.0 COG4961@1|root,COG4961@2|Bacteria,2GT3N@201174|Actinobacteria,4D1E4@85004|Bifidobacteriales 201174|Actinobacteria U TadE-like protein - - - - - - - - - - - - TadE BHPHKHDA_01421 326426.Bbr_0138 3.01e-70 213.0 2DRBM@1|root,33B4F@2|Bacteria,2HZRZ@201174|Actinobacteria,4D1G6@85004|Bifidobacteriales 201174|Actinobacteria S TIGRFAM helicase secretion neighborhood TadE-like protein - - - - - - - - - - - - Tad BHPHKHDA_01422 326426.Bbr_0139 1.09e-274 751.0 COG1597@1|root,COG1597@2|Bacteria,2GK3P@201174|Actinobacteria,4CZ1S@85004|Bifidobacteriales 201174|Actinobacteria I Diacylglycerol kinase catalytic domain protein - - 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat BHPHKHDA_01423 326426.Bbr_0140 2.69e-125 358.0 COG1309@1|root,COG1309@2|Bacteria,2GND5@201174|Actinobacteria,4CZUU@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N BHPHKHDA_01424 326426.Bbr_0141 0.0 1408.0 COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CZMY@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III subunit gamma tau dnaX GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 BHPHKHDA_01425 326426.Bbr_0142 9.94e-142 400.0 COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4CZRI@85004|Bifidobacteriales 201174|Actinobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - HHH,RecR,Toprim_4 BHPHKHDA_01426 216816.GS08_00040 2.81e-37 137.0 COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales 201174|Actinobacteria S ATPase domain predominantly from Archaea - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 BHPHKHDA_01427 326426.Bbr_0144 7.89e-270 741.0 COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase BHPHKHDA_01428 326426.Bbr_0145 1.1e-90 265.0 COG4823@1|root,COG4823@2|Bacteria 2|Bacteria V Abi-like protein - - - - - - - - - - - - Abi_2 BHPHKHDA_01429 326426.Bbr_0146 1.31e-245 673.0 COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4CYSX@85004|Bifidobacteriales 201174|Actinobacteria K Putative ATP-dependent DNA helicase recG C-terminal - - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AlbA_2,HATPase_c_4 BHPHKHDA_01430 326426.Bbr_0147 6.3e-174 486.0 COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4CYSD@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid kinase family ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 BHPHKHDA_01431 326426.Bbr_0148 6.76e-125 356.0 COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,4D00P@85004|Bifidobacteriales 201174|Actinobacteria E ACT domain ask GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 BHPHKHDA_01432 326426.Bbr_0149 7.59e-269 735.0 COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CZPY@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3708c Semialdhyde_dh,Semialdhyde_dhC BHPHKHDA_01433 216816.GS08_00795 2.83e-144 407.0 2C7PT@1|root,2ZXN2@2|Bacteria,2GM64@201174|Actinobacteria,4CYPY@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01434 326426.Bbr_0160 2.11e-221 610.0 COG0648@1|root,COG0648@2|Bacteria,2I8IU@201174|Actinobacteria,4D0HP@85004|Bifidobacteriales 201174|Actinobacteria L Domain of unknown function (DUF4862) - - - - - - - - - - - - DUF4862 BHPHKHDA_01435 326426.Bbr_0161 2.48e-228 630.0 COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4D0EX@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK BHPHKHDA_01436 326426.Bbr_0162 1.2e-162 454.0 COG3010@1|root,COG3010@2|Bacteria,2GTWV@201174|Actinobacteria,4CZK9@85004|Bifidobacteriales 201174|Actinobacteria G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) nanE - 5.1.3.9 ko:K01788 ko00520,map00520 - R02087 RC00290 ko00000,ko00001,ko01000 - - - NanE BHPHKHDA_01437 326426.Bbr_0163 4.05e-204 563.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - 3.5.1.106 ko:K15357 ko00760,ko01120,map00760,map01120 M00622 R09126 RC00323,RC02431 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 BHPHKHDA_01438 326426.Bbr_0164 0.0 1033.0 COG0747@1|root,COG0747@2|Bacteria,2GK4Y@201174|Actinobacteria,4CYSK@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle oppA7 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5,TAT_signal BHPHKHDA_01439 326426.Bbr_0165 2.11e-204 568.0 COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4D2RG@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component oppB6 - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 BHPHKHDA_01440 326426.Bbr_0166 0.0 1276.0 COG0444@1|root,COG1173@1|root,COG0444@2|Bacteria,COG1173@2|Bacteria,2GIXV@201174|Actinobacteria,4D0C4@85004|Bifidobacteriales 201174|Actinobacteria EP Oligopeptide/dipeptide transporter, C-terminal region oppCD2 - - ko:K02031,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,BPD_transp_1,OppC_N,oligo_HPY BHPHKHDA_01441 326426.Bbr_0167 2.39e-188 524.0 COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4CYR3@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities oppF - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY BHPHKHDA_01442 326426.Bbr_0168 1.83e-231 637.0 COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D04B@85004|Bifidobacteriales 201174|Actinobacteria EM Dihydrodipicolinate synthetase family nanA - 4.1.3.3,4.3.3.7 ko:K01639,ko:K01714 ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R01811,R10147 RC00159,RC00600,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS BHPHKHDA_01443 326426.Bbr_0169 3.54e-188 523.0 COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,4CYYE@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso BHPHKHDA_01444 762211.BSTEL_0833 4.83e-17 80.9 COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4CZKB@85004|Bifidobacteriales 201174|Actinobacteria G Amidohydrolase family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 BHPHKHDA_01445 326426.Bbr_0171 0.0 1541.0 COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria,4D02H@85004|Bifidobacteriales 201174|Actinobacteria G BNR repeat-like domain neu - 3.2.1.18 ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko02042 - GH33 - BNR_2,Laminin_G_3 BHPHKHDA_01446 326426.Bbr_0172 1.84e-312 852.0 COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria,4D0A9@85004|Bifidobacteriales 201174|Actinobacteria P Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143,TIR_2 BHPHKHDA_01447 326426.Bbr_0173 3.99e-196 544.0 COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,4D0K7@85004|Bifidobacteriales 201174|Actinobacteria K FCD - - - - - - - - - - - - FCD,GntR BHPHKHDA_01448 326426.Bbr_0174 0.0 941.0 COG1409@1|root,COG1409@2|Bacteria,2GNKK@201174|Actinobacteria,4CZMC@85004|Bifidobacteriales 201174|Actinobacteria S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos BHPHKHDA_01449 326426.Bbr_0175 0.0 1259.0 COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,4CZYW@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer BHPHKHDA_01450 326426.Bbr_0176 0.0 1428.0 COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZQZ@85004|Bifidobacteriales 201174|Actinobacteria M Transglycosylase pbp5 - - - - - - - - - - - Transgly,Transpeptidase BHPHKHDA_01451 326426.Bbr_0177 2.87e-214 598.0 COG0671@1|root,COG0671@2|Bacteria,2HIXE@201174|Actinobacteria,4CYS6@85004|Bifidobacteriales 201174|Actinobacteria I PAP2 superfamily - - - - - - - - - - - - PAP2 BHPHKHDA_01452 326426.Bbr_0178 0.0 1915.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4CZ85@85004|Bifidobacteriales 201174|Actinobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt BHPHKHDA_01453 326426.Bbr_0179 1.68e-149 421.0 COG0125@1|root,COG0125@2|Bacteria,2GNTI@201174|Actinobacteria,4CYQ8@85004|Bifidobacteriales 201174|Actinobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - MFS_1,MFS_3,Thymidylate_kin BHPHKHDA_01454 326426.Bbr_0180 1.85e-265 728.0 COG0470@1|root,COG0470@2|Bacteria,2GJ8C@201174|Actinobacteria,4CZ4Y@85004|Bifidobacteriales 201174|Actinobacteria L DNA polymerase III holB GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C BHPHKHDA_01455 326426.Bbr_0181 5.22e-137 389.0 COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4CZ05@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BHPHKHDA_01456 326426.Bbr_0182 1.47e-50 160.0 COG1925@1|root,COG1925@2|Bacteria,2GQX6@201174|Actinobacteria,4D19B@85004|Bifidobacteriales 201174|Actinobacteria G PTS HPr component phosphorylation site hpr - - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr BHPHKHDA_01457 326426.Bbr_0183 0.0 1031.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CZ52@85004|Bifidobacteriales 201174|Actinobacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C BHPHKHDA_01458 326426.Bbr_0186 5.95e-135 382.0 COG1881@1|root,COG1881@2|Bacteria,2I5K1@201174|Actinobacteria,4CZSW@85004|Bifidobacteriales 201174|Actinobacteria S Phosphatidylethanolamine-binding protein - - - ko:K06910 - - - - ko00000 - - - PBP BHPHKHDA_01459 326426.Bbr_0187 0.0 1068.0 COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CZI5@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family C69 pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 BHPHKHDA_01460 326426.Bbr_0188 0.0 981.0 COG2759@1|root,COG2759@2|Bacteria,2GT0X@201174|Actinobacteria,4CZ7P@85004|Bifidobacteriales 201174|Actinobacteria F Formate-tetrahydrofolate ligase fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS BHPHKHDA_01461 326426.Bbr_0189 1.11e-81 241.0 COG1942@1|root,COG1942@2|Bacteria,2II0W@201174|Actinobacteria,4D0VC@85004|Bifidobacteriales 201174|Actinobacteria S Macrophage migration inhibitory factor (MIF) - - - - - - - - - - - - MIF BHPHKHDA_01462 326426.Bbr_0190 1.29e-124 355.0 COG2246@1|root,COG2246@2|Bacteria,2HZBR@201174|Actinobacteria,4CZM6@85004|Bifidobacteriales 201174|Actinobacteria S GtrA-like protein - - - - - - - - - - - - GtrA BHPHKHDA_01463 326426.Bbr_0191 0.0 907.0 COG0477@1|root,COG2814@2|Bacteria,2GKMQ@201174|Actinobacteria,4CZ6D@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_01464 326426.Bbr_0192 4.34e-159 445.0 COG0406@1|root,COG0406@2|Bacteria,2GMXF@201174|Actinobacteria,4CZ0Z@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - - - - - - - - - - His_Phos_1 BHPHKHDA_01465 326426.Bbr_0193 3.5e-205 570.0 2BR5C@1|root,32K3E@2|Bacteria,2I8T9@201174|Actinobacteria,4CZ8U@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01466 326426.Bbr_0194 3.62e-289 789.0 COG2706@1|root,COG2706@2|Bacteria,2GNMK@201174|Actinobacteria,4D0CD@85004|Bifidobacteriales 201174|Actinobacteria G Lactonase, 7-bladed beta-propeller - - 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase BHPHKHDA_01467 326426.Bbr_0195 1.24e-227 638.0 COG3152@1|root,COG3152@2|Bacteria,2IQHK@201174|Actinobacteria,4D0Q2@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 BHPHKHDA_01469 326426.Bbr_0196 0.0 1007.0 COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,4CZHK@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - iNJ661.Rv2992c tRNA-synt_1c BHPHKHDA_01472 762211.BSTEL_1797 7e-38 139.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4D0EV@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase, N-terminal SAM-like domain intA - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase BHPHKHDA_01473 762211.BSTEL_1797 8.34e-28 112.0 COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4D0EV@85004|Bifidobacteriales 201174|Actinobacteria L Phage integrase, N-terminal SAM-like domain intA - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase BHPHKHDA_01475 326426.Bbr_0221 0.0 1131.0 COG0672@1|root,COG0672@2|Bacteria,2GJ22@201174|Actinobacteria,4D01C@85004|Bifidobacteriales 201174|Actinobacteria P Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 BHPHKHDA_01476 326426.Bbr_0222 1.89e-159 447.0 COG3470@1|root,COG3470@2|Bacteria,2GNAD@201174|Actinobacteria,4CZCG@85004|Bifidobacteriales 201174|Actinobacteria P Fe2+ transport protein - - - ko:K07230 - - - - ko00000,ko02000 2.A.108.2.10,2.A.108.2.4,2.A.108.2.9 - - Iron_transport BHPHKHDA_01477 326426.Bbr_0223 2.03e-291 797.0 COG4393@1|root,COG4393@2|Bacteria,2GMS6@201174|Actinobacteria,4CZ19@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2318) - - - - - - - - - - - - DUF2318 BHPHKHDA_01478 326426.Bbr_0224 6.04e-290 794.0 COG0577@1|root,COG0577@2|Bacteria,2I91N@201174|Actinobacteria,4CZGK@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BHPHKHDA_01479 326426.Bbr_0225 5.7e-278 766.0 COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4CZEZ@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BHPHKHDA_01480 216816.GS08_01100 1.14e-186 519.0 COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4CYTA@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01481 326426.Bbr_0227 6.54e-100 293.0 COG3976@1|root,COG3976@2|Bacteria,2IQ4E@201174|Actinobacteria,4D0YM@85004|Bifidobacteriales 201174|Actinobacteria S FMN_bind - - - - - - - - - - - - FMN_bind BHPHKHDA_01482 326426.Bbr_0228 1.62e-130 371.0 COG1309@1|root,COG1309@2|Bacteria,2HZI8@201174|Actinobacteria,4D0IS@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - TetR_C_9,TetR_N BHPHKHDA_01483 326426.Bbr_0229 0.0 1183.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 BHPHKHDA_01484 326426.Bbr_0230 0.0 1374.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3 BHPHKHDA_01485 326426.Bbr_0231 0.0 877.0 COG4905@1|root,COG4905@2|Bacteria,2IBSV@201174|Actinobacteria,4D05G@85004|Bifidobacteriales 201174|Actinobacteria S Putative ABC-transporter type IV - - - - - - - - - - - - ABC_trans_CmpB BHPHKHDA_01486 326426.Bbr_0232 0.0 965.0 COG0362@1|root,COG0362@2|Bacteria,2GJ2J@201174|Actinobacteria,4CZFG@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 BHPHKHDA_01487 326426.Bbr_0233 3.54e-193 536.0 COG0363@1|root,COG0363@2|Bacteria,2GMQ2@201174|Actinobacteria,4CZRG@85004|Bifidobacteriales 201174|Actinobacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso BHPHKHDA_01488 326426.Bbr_0234 8.56e-247 677.0 COG3429@1|root,COG3429@2|Bacteria,2GJ1H@201174|Actinobacteria,4CZI4@85004|Bifidobacteriales 201174|Actinobacteria G Glucose-6-phosphate dehydrogenase subunit opcA - - - - - - - - - - - OpcA_G6PD_assem BHPHKHDA_01489 326426.Bbr_0235 0.0 1039.0 COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CYQM@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N BHPHKHDA_01490 326426.Bbr_0236 0.0 1028.0 COG2367@1|root,COG2367@2|Bacteria,2HZMP@201174|Actinobacteria,4D0YE@85004|Bifidobacteriales 201174|Actinobacteria V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 BHPHKHDA_01492 326426.Bbr_0237 0.0 1035.0 COG4690@1|root,COG4690@2|Bacteria,2GM80@201174|Actinobacteria,4CYT0@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family C69 - - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 BHPHKHDA_01493 326426.Bbr_0238 2.2e-251 689.0 COG0463@1|root,COG0463@2|Bacteria,2GMDK@201174|Actinobacteria,4CZIS@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - 2.7.8.12 ko:K09809 - - - - ko00000,ko01000 - - - Glycos_transf_2 BHPHKHDA_01494 326426.Bbr_0239 4.13e-193 536.0 COG1309@1|root,COG1309@2|Bacteria,2GMBW@201174|Actinobacteria,4CYUD@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family icaR - - - - - - - - - - - TetR_N BHPHKHDA_01495 326426.Bbr_0240 1.69e-233 650.0 COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,4CZZX@85004|Bifidobacteriales 201174|Actinobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N BHPHKHDA_01496 326426.Bbr_0241 1.12e-304 831.0 COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CZA0@85004|Bifidobacteriales 201174|Actinobacteria U Ammonium Transporter Family amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp BHPHKHDA_01497 1435051.BMOU_1470 1.27e-72 218.0 COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4D0VD@85004|Bifidobacteriales 201174|Actinobacteria K Nitrogen regulatory protein P-II glnB GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II BHPHKHDA_01498 326426.Bbr_0243 0.0 1213.0 COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria,4D07P@85004|Bifidobacteriales 201174|Actinobacteria O Nucleotidyltransferase domain glnD GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 BHPHKHDA_01499 326426.Bbr_0244 4.25e-305 834.0 COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria,4CZ75@85004|Bifidobacteriales 201174|Actinobacteria V MatE dinF - - - - - - - - - - - MatE BHPHKHDA_01500 216816.GS08_01205 0.0 885.0 COG0305@1|root,COG0305@2|Bacteria,2GKXQ@201174|Actinobacteria,4CYY3@85004|Bifidobacteriales 201174|Actinobacteria L Participates in initiation and elongation during chromosome replication dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C BHPHKHDA_01501 326426.Bbr_0246 0.0 900.0 COG0771@1|root,COG0771@2|Bacteria,2GK18@201174|Actinobacteria,4CYTP@85004|Bifidobacteriales 201174|Actinobacteria M Domain of unknown function (DUF1727) murE - - - - - - - - - - - DUF1727,Mur_ligase_M BHPHKHDA_01502 326426.Bbr_0247 1.29e-180 502.0 COG3442@1|root,COG3442@2|Bacteria,2GKPV@201174|Actinobacteria,4CZJ1@85004|Bifidobacteriales 201174|Actinobacteria S CobB/CobQ-like glutamine amidotransferase domain cobQ2 - - ko:K07009 - - - - ko00000 - - - GATase_3 BHPHKHDA_01503 326426.Bbr_0248 1.91e-52 166.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 201174|Actinobacteria S granule-associated protein - - - - - - - - - - - - Phasin BHPHKHDA_01504 326426.Bbr_0249 0.0 1157.0 COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CZ45@85004|Bifidobacteriales 201174|Actinobacteria S ABC1 family - - - ko:K03688 - - - - ko00000 - - - ABC1 BHPHKHDA_01505 566552.BIFCAT_02011 2.87e-89 270.0 COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CZND@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BHPHKHDA_01506 158787.BSCA_0640 1.39e-296 825.0 COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria,4CYSU@85004|Bifidobacteriales 201174|Actinobacteria S Beta-L-arabinofuranosidase, GH127 - - 3.2.1.185 ko:K09955,ko:K18205 - - - - ko00000,ko01000 - GH127 - Glyco_hydro_127 BHPHKHDA_01507 326426.Bbr_0252 3.01e-197 548.0 COG0325@1|root,COG0325@2|Bacteria,2GMRJ@201174|Actinobacteria,4CZUY@85004|Bifidobacteriales 201174|Actinobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N BHPHKHDA_01508 216816.GS08_01250 3.31e-238 655.0 COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,4CZPM@85004|Bifidobacteriales 201174|Actinobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N BHPHKHDA_01509 702459.BBPR_0072 6e-244 670.0 COG1215@1|root,COG1215@2|Bacteria,2I2H4@201174|Actinobacteria,4CYWJ@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 BHPHKHDA_01511 326426.Bbr_1790 6.86e-213 609.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase BHPHKHDA_01512 762211.BSTEL_1629 4.24e-78 255.0 COG4713@1|root,COG4713@2|Bacteria,2IAIH@201174|Actinobacteria,4D08G@85004|Bifidobacteriales 201174|Actinobacteria S Predicted membrane protein (DUF2142) - - - - - - - - - - - - DUF2142 BHPHKHDA_01513 216816.GS08_00950 9.3e-149 432.0 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_01514 702459.BBPR_0168 7.54e-186 527.0 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_01515 326426.Bbr_0204 6.93e-06 50.1 COG0331@1|root,COG1028@1|root,COG3321@1|root,COG0331@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,2HZQU@201174|Actinobacteria,4D1A9@85004|Bifidobacteriales 201174|Actinobacteria IQ [acyl-carrier-protein] S-malonyltransferase activity - - - - - - - - - - - - Acyl_transf_1,KR,PP-binding,PS-DH BHPHKHDA_01516 216816.GS08_00960 4.51e-148 417.0 COG1309@1|root,COG1309@2|Bacteria,2IRA8@201174|Actinobacteria,4D0DY@85004|Bifidobacteriales 201174|Actinobacteria K WHG domain - - - - - - - - - - - - TetR_N,WHG BHPHKHDA_01517 326426.Bbr_0209 1.75e-143 406.0 COG2977@1|root,COG2977@2|Bacteria,2IIA2@201174|Actinobacteria,4D0IW@85004|Bifidobacteriales 201174|Actinobacteria Q 4'-phosphopantetheinyl transferase superfamily - - - - - - - - - - - - ACPS BHPHKHDA_01518 216816.GS08_05945 3.1e-80 239.0 COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_21,HTH_28,rve,rve_2 BHPHKHDA_01519 326426.Bbr_1855 8.96e-212 597.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZT7@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain protein - - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C BHPHKHDA_01520 326426.Bbr_1854 3.3e-295 806.0 COG1171@1|root,COG1171@2|Bacteria,2GJAG@201174|Actinobacteria,4CYW0@85004|Bifidobacteriales 201174|Actinobacteria E Pyridoxal-phosphate dependent enzyme ilvA GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0016020,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1559 PALP,Thr_dehydrat_C BHPHKHDA_01521 326426.Bbr_1853 2.06e-182 507.0 COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4CYUW@85004|Bifidobacteriales 201174|Actinobacteria K Sir2 family cobB2 - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 BHPHKHDA_01522 1437608.BBIA_0824 2.62e-29 104.0 2BA3Q@1|root,323HI@2|Bacteria,2H863@201174|Actinobacteria,4D2FS@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01523 1437608.BBIA_0825 4.53e-16 72.8 2AWD3@1|root,31N90@2|Bacteria,2IP9B@201174|Actinobacteria,4D14C@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01525 326426.Bbr_1507 3.89e-212 586.0 COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4CZKF@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 BHPHKHDA_01526 326426.Bbr_0561 1.08e-111 321.0 COG0225@1|root,COG0225@2|Bacteria 2|Bacteria O peptide-methionine (S)-S-oxide reductase activity msrA - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR BHPHKHDA_01527 326426.Bbr_0560 0.0 1074.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 BHPHKHDA_01528 216816.GS08_10200 1.98e-18 79.0 COG2963@1|root,COG2963@2|Bacteria,2IRD7@201174|Actinobacteria,4D16D@85004|Bifidobacteriales 201174|Actinobacteria L Psort location Cytoplasmic, score 8.87 - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 BHPHKHDA_01529 326426.Bbr_0559 1.84e-212 598.0 COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4CZT7@85004|Bifidobacteriales 201174|Actinobacteria G Alpha amylase, catalytic domain protein - - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C BHPHKHDA_01532 326426.Bbr_1070 9.49e-32 115.0 2AYSN@1|root,31QXY@2|Bacteria,2ISV3@201174|Actinobacteria,4D18V@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01533 326426.Bbr_1071 1.73e-174 488.0 2B5A1@1|root,31Y46@2|Bacteria,2HZNW@201174|Actinobacteria,4D13D@85004|Bifidobacteriales 201174|Actinobacteria - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - BHPHKHDA_01534 326426.Bbr_1072 2.55e-212 586.0 COG1131@1|root,COG1131@2|Bacteria,2GNQJ@201174|Actinobacteria,4D0SJ@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran BHPHKHDA_01536 78345.BMERY_1170 3.33e-217 603.0 COG3594@1|root,COG3594@2|Bacteria,2GPJB@201174|Actinobacteria,4D1BX@85004|Bifidobacteriales 201174|Actinobacteria G Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 BHPHKHDA_01537 326426.Bbr_0152 0.0 1024.0 COG4584@1|root,COG4584@2|Bacteria,2IBDV@201174|Actinobacteria,4CZS6@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - rve BHPHKHDA_01538 216816.GS08_04250 0.0 897.0 COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4D2W9@85004|Bifidobacteriales 201174|Actinobacteria EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 BHPHKHDA_01539 216816.GS08_04255 1.92e-66 216.0 COG0515@1|root,COG0515@2|Bacteria,2IB6I@201174|Actinobacteria,4D0BZ@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase BHPHKHDA_01540 326426.Bbr_0039 0.0 1135.0 COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,2GKD2@201174|Actinobacteria,4CZ6G@85004|Bifidobacteriales 201174|Actinobacteria C Thioredoxin domain - - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Thioredoxin_3 BHPHKHDA_01541 326426.Bbr_0038 6.83e-138 389.0 COG0450@1|root,COG0450@2|Bacteria,2GM74@201174|Actinobacteria,4CZXS@85004|Bifidobacteriales 201174|Actinobacteria O C-terminal domain of 1-Cys peroxiredoxin ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA BHPHKHDA_01542 326426.Bbr_0037 3.01e-154 434.0 COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,4D06V@85004|Bifidobacteriales 201174|Actinobacteria P Reversible hydration of carbon dioxide cah - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA BHPHKHDA_01543 326426.Bbr_0036 2.08e-264 725.0 COG1672@1|root,COG1672@2|Bacteria,2GWBV@201174|Actinobacteria,4CZV8@85004|Bifidobacteriales 201174|Actinobacteria S AAA ATPase domain - - - - - - - - - - - - AAA_16 BHPHKHDA_01544 326426.Bbr_0035 3.58e-300 821.0 COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CZKA@85004|Bifidobacteriales 201174|Actinobacteria P Transporter associated domain - - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 BHPHKHDA_01545 326426.Bbr_0016 1.55e-109 315.0 COG0783@1|root,COG0783@2|Bacteria,2IFDP@201174|Actinobacteria,4CZV3@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin BHPHKHDA_01546 216816.GS08_00120 0.0 880.0 COG1373@1|root,COG1373@2|Bacteria,2GM3Y@201174|Actinobacteria,4D05H@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_01547 326426.Bbr_0014 3.46e-157 441.0 COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,4CZF9@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 BHPHKHDA_01550 77635.BISU_1235 4e-21 93.2 COG1373@1|root,COG1373@2|Bacteria,2GK1Q@201174|Actinobacteria,4CZNQ@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_01551 326426.Bbr_0013 3.64e-252 690.0 28H6R@1|root,2Z7J3@2|Bacteria,2I9RC@201174|Actinobacteria,4CZ7J@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - BHPHKHDA_01552 326426.Bbr_0012 0.0 884.0 COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CYTN@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N BHPHKHDA_01553 326426.Bbr_0011 3.42e-259 714.0 COG4767@1|root,COG4767@2|Bacteria,2H595@201174|Actinobacteria,4CZBZ@85004|Bifidobacteriales 201174|Actinobacteria V VanZ like family - - - - - - - - - - - - RDD,VanZ BHPHKHDA_01554 326426.Bbr_0010 0.0 2036.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3 BHPHKHDA_01555 762211.BSTEL_0991 2.81e-13 73.2 COG2211@1|root,COG2211@2|Bacteria,2HD4Y@201174|Actinobacteria,4CZRA@85004|Bifidobacteriales 201174|Actinobacteria G Psort location CytoplasmicMembrane, score 10.00 gph - - ko:K16209 - - - - ko00000,ko02000 2.A.2.2 - - MFS_2 BHPHKHDA_01556 326426.Bbr_0008 3.55e-233 642.0 COG1609@1|root,COG1609@2|Bacteria,2H5ZG@201174|Actinobacteria,4CZ8A@85004|Bifidobacteriales 201174|Actinobacteria K Transcriptional regulator, LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BHPHKHDA_01557 326426.Bbr_0007 6.05e-89 265.0 COG3266@1|root,COG3266@2|Bacteria,2GKZP@201174|Actinobacteria,4D0XB@85004|Bifidobacteriales 201174|Actinobacteria S Transmembrane domain of unknown function (DUF3566) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF3566 BHPHKHDA_01558 326426.Bbr_0006 0.0 1759.0 COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYRP@85004|Bifidobacteriales 201174|Actinobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0008094,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034335,GO:0042623,GO:0061505,GO:0140097 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV BHPHKHDA_01559 326426.Bbr_0005 0.0 1371.0 COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CZ47@85004|Bifidobacteriales 201174|Actinobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim BHPHKHDA_01560 326426.Bbr_0004 3.41e-107 309.0 COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4D157@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF721) - - - - - - - - - - - - DUF721 BHPHKHDA_01561 326426.Bbr_0003 2.26e-256 704.0 COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4CZQT@85004|Bifidobacteriales 201174|Actinobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N BHPHKHDA_01562 326426.Bbr_0002 4.88e-261 716.0 COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,4CZTV@85004|Bifidobacteriales 201174|Actinobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 BHPHKHDA_01563 326426.Bbr_0001 0.0 966.0 COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,4CZDW@85004|Bifidobacteriales 201174|Actinobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C BHPHKHDA_01564 326426.Bbr_1926 4.62e-20 80.5 COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,4D1EF@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 BHPHKHDA_01565 326426.Bbr_1925 2.15e-75 225.0 COG0594@1|root,COG0594@2|Bacteria,2HZPS@201174|Actinobacteria,4D16S@85004|Bifidobacteriales 201174|Actinobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P BHPHKHDA_01566 326426.Bbr_1923 2.94e-236 650.0 COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,4CYZ2@85004|Bifidobacteriales 201174|Actinobacteria U Membrane protein insertase, YidC Oxa1 family yidC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP BHPHKHDA_01567 326426.Bbr_1922 1.97e-119 342.0 COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CYQQ@85004|Bifidobacteriales 201174|Actinobacteria S Putative single-stranded nucleic acids-binding domain jag - - ko:K06346 - - - - ko00000 - - - KH_4,R3H BHPHKHDA_01568 326426.Bbr_1921 3.56e-159 446.0 COG0357@1|root,COG0357@2|Bacteria,2GM9Z@201174|Actinobacteria,4CZ29@85004|Bifidobacteriales 201174|Actinobacteria J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB BHPHKHDA_01569 326426.Bbr_1920 5.17e-223 615.0 COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CZ2D@85004|Bifidobacteriales 201174|Actinobacteria D CobQ CobB MinD ParA nucleotide binding domain protein parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 BHPHKHDA_01570 326426.Bbr_1919 3.33e-285 781.0 COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4CYUE@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the ParB family parB GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc BHPHKHDA_01571 326426.Bbr_1918 2.45e-225 623.0 COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CYU9@85004|Bifidobacteriales 201174|Actinobacteria C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 BHPHKHDA_01572 326426.Bbr_1917 0.0 2236.0 COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CZ8M@85004|Bifidobacteriales 201174|Actinobacteria KLT MviN-like protein mviN GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN BHPHKHDA_01573 326426.Bbr_1916 0.0 1296.0 2CETP@1|root,33P5Y@2|Bacteria,2GMJ0@201174|Actinobacteria,4CZCV@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01574 326426.Bbr_1915 5.27e-211 585.0 COG0494@1|root,COG0494@2|Bacteria,2GWEB@201174|Actinobacteria,4CZAV@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the Nudix hydrolase family mutT4 - - - - - - - - - - - NUDIX BHPHKHDA_01575 326426.Bbr_1914 0.0 964.0 COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria,4CYUH@85004|Bifidobacteriales 201174|Actinobacteria J Probable RNA and SrmB- binding site of polymerase A pcnA - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd BHPHKHDA_01576 326426.Bbr_1913 4.16e-143 404.0 2E1BJ@1|root,32WRF@2|Bacteria,2IKG0@201174|Actinobacteria,4D0S1@85004|Bifidobacteriales 201174|Actinobacteria S LytR cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C BHPHKHDA_01577 326426.Bbr_1912 2.47e-222 613.0 COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,4CZMW@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N BHPHKHDA_01578 326426.Bbr_1911 7.89e-216 596.0 COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4CYS9@85004|Bifidobacteriales 201174|Actinobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD BHPHKHDA_01579 326426.Bbr_1910 6.72e-282 778.0 COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4CYY0@85004|Bifidobacteriales 201174|Actinobacteria S G5 rpfB GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - ko:K21688 - - - - ko00000 - - - DUF348,G5,Transglycosylas BHPHKHDA_01581 326426.Bbr_1909 2.54e-181 510.0 COG1651@1|root,COG1651@2|Bacteria,2GN3N@201174|Actinobacteria,4CZBD@85004|Bifidobacteriales 201174|Actinobacteria O Thioredoxin - - - - - - - - - - - - Thioredoxin_4 BHPHKHDA_01582 326426.Bbr_1908 0.0 1370.0 COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4CYQG@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase - - - - - - - - - - - - Pkinase BHPHKHDA_01583 78346.BRUM_1778 1.97e-143 434.0 COG1472@1|root,COG1472@2|Bacteria,2GQQR@201174|Actinobacteria,4CZ02@85004|Bifidobacteriales 201174|Actinobacteria G Fibronectin type III-like domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C BHPHKHDA_01584 158787.BSCA_1571 4.57e-152 429.0 COG3279@1|root,COG3279@2|Bacteria,2GKK5@201174|Actinobacteria,4D0X5@85004|Bifidobacteriales 201174|Actinobacteria T LytTr DNA-binding domain - - - - - - - - - - - - LytTR,Response_reg BHPHKHDA_01585 1437610.BREU_1973 2.82e-167 483.0 COG3290@1|root,COG3290@2|Bacteria,2IH0T@201174|Actinobacteria,4D0U8@85004|Bifidobacteriales 201174|Actinobacteria T GHKL domain - - - - - - - - - - - - HATPase_c_5 BHPHKHDA_01586 326426.Bbr_1907 0.0 1878.0 COG1472@1|root,COG1472@2|Bacteria,2GQQR@201174|Actinobacteria,4CZ02@85004|Bifidobacteriales 201174|Actinobacteria G Fibronectin type III-like domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C BHPHKHDA_01587 216816.GS08_10485 1.03e-73 228.0 COG1226@1|root,COG1226@2|Bacteria,2GKNF@201174|Actinobacteria,4CZUV@85004|Bifidobacteriales 201174|Actinobacteria U Ion channel - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans_2 BHPHKHDA_01588 326426.Bbr_1905 5.89e-161 451.0 28KQ0@1|root,2ZA7Z@2|Bacteria,2IB0B@201174|Actinobacteria,4D2XM@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3990) - - - - - - - - - - - - DUF3990 BHPHKHDA_01589 326426.Bbr_1904 7.8e-156 437.0 COG1396@1|root,COG1396@2|Bacteria,2IF66@201174|Actinobacteria,4CZYD@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,HTH_31 BHPHKHDA_01590 326426.Bbr_1903 0.0 1609.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZ2P@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 3 N-terminal domain protein - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C BHPHKHDA_01591 326426.Bbr_1902 6.17e-158 442.0 28NMC@1|root,2ZA4G@2|Bacteria,2IG2S@201174|Actinobacteria,4D0T5@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - BHPHKHDA_01593 326426.Bbr_1901 1.34e-56 176.0 COG0695@1|root,COG0695@2|Bacteria,2IRCP@201174|Actinobacteria,4D17U@85004|Bifidobacteriales 201174|Actinobacteria O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin BHPHKHDA_01594 326426.Bbr_1900 8.53e-115 329.0 COG1780@1|root,COG1780@2|Bacteria,2IM4D@201174|Actinobacteria,4D0XV@85004|Bifidobacteriales 201174|Actinobacteria F Probably involved in ribonucleotide reductase function nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI BHPHKHDA_01595 326426.Bbr_1899 0.0 1428.0 COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4CZF3@85004|Bifidobacteriales 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0016728,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0051063,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN BHPHKHDA_01597 326426.Bbr_1898 1.26e-243 668.0 COG0208@1|root,COG0208@2|Bacteria,2GK46@201174|Actinobacteria,4CYQ2@85004|Bifidobacteriales 201174|Actinobacteria F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_sm BHPHKHDA_01598 326426.Bbr_1895 1.68e-274 751.0 COG0463@1|root,COG0463@2|Bacteria,2I2GT@201174|Actinobacteria,4CZ0W@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 BHPHKHDA_01599 326426.Bbr_1894 1.66e-95 278.0 COG1762@1|root,COG1762@2|Bacteria,2I8CH@201174|Actinobacteria,4D0XI@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 BHPHKHDA_01600 326426.Bbr_1893 1.04e-60 187.0 COG3414@1|root,COG3414@2|Bacteria,2IQ7W@201174|Actinobacteria,4D161@85004|Bifidobacteriales 201174|Actinobacteria G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB BHPHKHDA_01601 326426.Bbr_1892 3.12e-307 840.0 COG3037@1|root,COG3037@2|Bacteria,2GMYV@201174|Actinobacteria,4D064@85004|Bifidobacteriales 201174|Actinobacteria S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT BHPHKHDA_01602 326426.Bbr_1891 7.15e-176 490.0 COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4D0IV@85004|Bifidobacteriales 201174|Actinobacteria K UTRA domain - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA BHPHKHDA_01603 326426.Bbr_1890 7.62e-270 738.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CYU6@85004|Bifidobacteriales 201174|Actinobacteria E Belongs to the ABC transporter superfamily ugpC - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 BHPHKHDA_01604 326426.Bbr_1889 2.53e-60 212.0 2CBRJ@1|root,2Z7W0@2|Bacteria,2GKSC@201174|Actinobacteria,4CZAS@85004|Bifidobacteriales 201174|Actinobacteria S LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Cna_B,Gram_pos_anchor BHPHKHDA_01605 1437608.BBIA_0795 7.18e-31 120.0 COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2HRER@201174|Actinobacteria,4D28U@85004|Bifidobacteriales 201174|Actinobacteria L Winged helix-turn helix - - - - - - - - - - - - HTH_29 BHPHKHDA_01607 1437610.BREU_2152 2.72e-231 650.0 2BXKA@1|root,2Z9RJ@2|Bacteria,2HAKJ@201174|Actinobacteria,4D1VX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01608 1437610.BREU_2151 4.32e-191 536.0 COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4D2SM@85004|Bifidobacteriales 201174|Actinobacteria U Branched-chain amino acid transport system / permease component - - - ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 BHPHKHDA_01609 1437610.BREU_2150 3.89e-223 630.0 COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4CZ8Y@85004|Bifidobacteriales 201174|Actinobacteria G ATPases associated with a variety of cellular activities rbsA - 3.6.3.17 ko:K10441,ko:K10542,ko:K17215 ko02010,map02010 M00212,M00214,M00593 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3 - - ABC_tran BHPHKHDA_01610 1437610.BREU_1627 6.91e-187 524.0 COG1879@1|root,COG1879@2|Bacteria,2I2HU@201174|Actinobacteria,4CZS9@85004|Bifidobacteriales 201174|Actinobacteria G Periplasmic binding protein domain rbsB - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 BHPHKHDA_01611 1437610.BREU_1626 1.13e-166 476.0 COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4D12S@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 BHPHKHDA_01612 398513.BBNG_00723 7.31e-22 93.6 COG2801@1|root,COG2801@2|Bacteria,2GKDY@201174|Actinobacteria,4CZUB@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain tnp3521a2 - - - - - - - - - - - HTH_21,rve,rve_3 BHPHKHDA_01613 326426.Bbr_1889 0.0 990.0 2CBRJ@1|root,2Z7W0@2|Bacteria,2GKSC@201174|Actinobacteria,4CZAS@85004|Bifidobacteriales 201174|Actinobacteria S LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - Cna_B,Gram_pos_anchor BHPHKHDA_01614 326426.Bbr_1888 0.0 926.0 COG4932@1|root,COG4932@2|Bacteria,2H1EY@201174|Actinobacteria,4D00Q@85004|Bifidobacteriales 201174|Actinobacteria M LPXTG-motif cell wall anchor domain protein - - - - - - - - - - - - GramPos_pilinBB,Gram_pos_anchor BHPHKHDA_01615 326426.Bbr_1887 3.02e-229 632.0 COG3764@1|root,COG3764@2|Bacteria,2GNWT@201174|Actinobacteria,4CZMM@85004|Bifidobacteriales 201174|Actinobacteria M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase BHPHKHDA_01616 547043.BIFPSEUDO_03202 1.22e-175 491.0 2EUBW@1|root,33MU8@2|Bacteria,2ICS5@201174|Actinobacteria,4D08R@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01617 326426.Bbr_1885 0.0 933.0 COG0515@1|root,COG0515@2|Bacteria,2I2F0@201174|Actinobacteria,4CZ2E@85004|Bifidobacteriales 201174|Actinobacteria KLT Domain of unknown function (DUF4032) - - - - - - - - - - - - DUF4032,Kdo BHPHKHDA_01618 326426.Bbr_1884 0.0 1034.0 COG4468@1|root,COG4468@2|Bacteria,2HNCF@201174|Actinobacteria,4CZT3@85004|Bifidobacteriales 201174|Actinobacteria G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf BHPHKHDA_01619 326426.Bbr_1883 2.35e-210 580.0 COG0676@1|root,COG0676@2|Bacteria,2IIUH@201174|Actinobacteria,4CZWN@85004|Bifidobacteriales 201174|Actinobacteria G Aldose 1-epimerase - - 5.1.3.15 ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 - R02739 RC00563 ko00000,ko00001,ko01000 - - - Aldose_epim BHPHKHDA_01620 326426.Bbr_1882 3.08e-220 609.0 COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,4CZB1@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family rlmB GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind BHPHKHDA_01621 158190.SpiGrapes_1827 8.98e-27 110.0 2BHII@1|root,32BKY@2|Bacteria,2JB5E@203691|Spirochaetes 203691|Spirochaetes - - - - - - - - - - - - - - - BHPHKHDA_01622 1437610.BREU_2042 5.1e-160 452.0 COG0657@1|root,COG0657@2|Bacteria,2HZCA@201174|Actinobacteria,4CZQE@85004|Bifidobacteriales 201174|Actinobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Peptidase_S9 BHPHKHDA_01623 326426.Bbr_1877 0.0 1838.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CZ1I@85004|Bifidobacteriales 201174|Actinobacteria P Cation transporter/ATPase, N-terminus pacL2 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 BHPHKHDA_01624 326426.Bbr_1876 1.14e-105 328.0 2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D00F@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - FIVAR BHPHKHDA_01625 326426.Bbr_1875 1.43e-142 401.0 COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4CZEB@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the dCTP deaminase family dcd GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - DCD BHPHKHDA_01626 326426.Bbr_1874 2.47e-193 538.0 2BFMF@1|root,329FS@2|Bacteria,2IGC7@201174|Actinobacteria,4D0RD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01627 326426.Bbr_1873 6.17e-189 523.0 COG0400@1|root,COG0400@2|Bacteria,2I5NR@201174|Actinobacteria,4CZJQ@85004|Bifidobacteriales 201174|Actinobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 BHPHKHDA_01628 326426.Bbr_1872 1.02e-158 448.0 COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4CZFS@85004|Bifidobacteriales 201174|Actinobacteria S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE BHPHKHDA_01629 326426.Bbr_1871 0.0 1290.0 COG0025@1|root,COG0025@2|Bacteria,2GIUT@201174|Actinobacteria,4CZC4@85004|Bifidobacteriales 201174|Actinobacteria P Sodium/hydrogen exchanger family nhaP - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger BHPHKHDA_01630 326426.Bbr_1870 1.77e-102 296.0 COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4D0V0@85004|Bifidobacteriales 201174|Actinobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.1,3.5.4.33 ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922,R10223 RC00074,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 BHPHKHDA_01631 326426.Bbr_1869 0.0 1546.0 COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria,4CZJB@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 36 N-terminal domain - - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase BHPHKHDA_01632 326426.Bbr_1868 8.97e-294 801.0 COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2GMBH@201174|Actinobacteria,4CZK4@85004|Bifidobacteriales 201174|Actinobacteria GK ROK family - - - - - - - - - - - - ROK BHPHKHDA_01633 326426.Bbr_1867 3.13e-310 845.0 COG1653@1|root,COG1653@2|Bacteria,2GN9T@201174|Actinobacteria,4CZ4V@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_01634 326426.Bbr_1866 5.6e-206 572.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZPG@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_01635 326426.Bbr_1865 7.15e-197 546.0 COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4D02Q@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_01637 216816.GS08_04820 8.17e-112 325.0 COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales 201174|Actinobacteria L IstB-like ATP binding protein istB - - - - - - - - - - - IstB_IS21 BHPHKHDA_01638 1203567.HMPREF1286_00566 7.85e-290 789.0 COG3677@1|root,COG3677@2|Bacteria,2IEJD@201174|Actinobacteria,22KBK@1653|Corynebacteriaceae 201174|Actinobacteria L Transposase and inactivated derivatives - - - - - - - - - - - - Transposase_mut BHPHKHDA_01639 326426.Bbr_1068 2.94e-98 287.0 COG1595@1|root,COG1595@2|Bacteria,2HG2H@201174|Actinobacteria,4D1CQ@85004|Bifidobacteriales 201174|Actinobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 BHPHKHDA_01641 702459.BBPR_0778 4.15e-134 389.0 COG2826@1|root,COG2826@2|Bacteria,2GMZX@201174|Actinobacteria,4D0DN@85004|Bifidobacteriales 201174|Actinobacteria L Transposase and inactivated derivatives IS30 family - - - - - - - - - - - - HTH_38,rve BHPHKHDA_01646 1437600.JDUI01000024_gene1208 8.55e-85 261.0 COG2801@1|root,COG2801@2|Bacteria,2I8Z0@201174|Actinobacteria,4D0BU@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - - - - - - - - - - rve BHPHKHDA_01647 326426.Bbr_1239 9.49e-178 496.0 COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CZ09@85004|Bifidobacteriales 201174|Actinobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigH GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 BHPHKHDA_01648 326426.Bbr_1238 1.14e-68 207.0 29M53@1|root,3082I@2|Bacteria,2GTWX@201174|Actinobacteria,4D1EJ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01649 326426.Bbr_1237 2.24e-238 654.0 COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales 201174|Actinobacteria G Aldose 1-epimerase - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim BHPHKHDA_01650 326426.Bbr_1236 1.41e-243 667.0 COG2017@1|root,COG2017@2|Bacteria,2GJ0H@201174|Actinobacteria,4CYWN@85004|Bifidobacteriales 201174|Actinobacteria G Aldose 1-epimerase - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim BHPHKHDA_01651 326426.Bbr_1235 5.06e-234 644.0 COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CZ8B@85004|Bifidobacteriales 201174|Actinobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB BHPHKHDA_01652 326426.Bbr_1234 4.92e-115 330.0 COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria,4CZFI@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit BHPHKHDA_01653 216816.GS08_06425 2.03e-251 690.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N BHPHKHDA_01654 326426.Bbr_1232 1.1e-172 481.0 COG1564@1|root,COG1564@2|Bacteria,2HQZZ@201174|Actinobacteria,4CZBY@85004|Bifidobacteriales 201174|Actinobacteria H Thiamin pyrophosphokinase, vitamin B1 binding domain - - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic BHPHKHDA_01655 1437610.BREU_1465 4.29e-08 55.5 COG4262@1|root,COG4262@2|Bacteria,2I372@201174|Actinobacteria,4D060@85004|Bifidobacteriales 201174|Actinobacteria S Spermine/spermidine synthase domain - - - - - - - - - - - - Spermine_synth BHPHKHDA_01656 326426.Bbr_1230 1.72e-157 445.0 COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CZA3@85004|Bifidobacteriales 201174|Actinobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N BHPHKHDA_01657 326426.Bbr_1229 2.72e-34 117.0 COG0291@1|root,COG0291@2|Bacteria,2HZRM@201174|Actinobacteria,4D1EV@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L35 rpmI - - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p BHPHKHDA_01658 326426.Bbr_1228 1.57e-80 239.0 COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 BHPHKHDA_01659 326426.Bbr_1227 2.1e-251 692.0 COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,4CZRH@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase BHPHKHDA_01660 326426.Bbr_1226 7.82e-183 512.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZ69@85004|Bifidobacteriales 201174|Actinobacteria D recombinase XerD xerD GO:0008150,GO:0040007 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase BHPHKHDA_01661 216816.GS08_06395 1.34e-191 534.0 COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4CYV4@85004|Bifidobacteriales 201174|Actinobacteria D CobQ CobB MinD ParA nucleotide binding domain protein soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 BHPHKHDA_01662 216816.GS08_06390 1.93e-193 539.0 COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,4CYRV@85004|Bifidobacteriales 201174|Actinobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA BHPHKHDA_01663 216816.GS08_06385 1.11e-150 426.0 COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,4D0QW@85004|Bifidobacteriales 201174|Actinobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB BHPHKHDA_01664 216816.GS08_06380 4.33e-196 543.0 COG1051@1|root,COG1051@2|Bacteria,2GNMT@201174|Actinobacteria,4CZNZ@85004|Bifidobacteriales 201174|Actinobacteria F NUDIX hydrolase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX BHPHKHDA_01665 326426.Bbr_1221 0.0 865.0 COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,4D0AI@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA BHPHKHDA_01666 326426.Bbr_1220 0.0 1016.0 COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,4D01P@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the oxidation of L-aspartate to iminoaspartate nadB GO:0008150,GO:0040007 1.4.3.16,2.4.2.19 ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 M00115 R00357,R00481,R03348 RC00006,RC02566,RC02877 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1595 FAD_binding_2,Succ_DH_flav_C BHPHKHDA_01667 326426.Bbr_1219 1.07e-207 575.0 COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,4CZWA@85004|Bifidobacteriales 201174|Actinobacteria H Quinolinate phosphoribosyl transferase, N-terminal domain nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N BHPHKHDA_01668 326426.Bbr_1218 1.92e-301 823.0 COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CZVW@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-V iscS1 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 BHPHKHDA_01669 216816.GS08_06355 3.49e-24 100.0 COG0477@1|root,COG0477@2|Bacteria,2HC9X@201174|Actinobacteria,4D2V1@85004|Bifidobacteriales 201174|Actinobacteria U Sugar (and other) transporter nanT - - ko:K03290,ko:K08178,ko:K08369 - - - - ko00000,ko02000 2.A.1,2.A.1.12 - - MFS_1,Sugar_tr BHPHKHDA_01670 326426.Bbr_1216 0.0 1937.0 COG0577@1|root,COG0577@2|Bacteria,2GN24@201174|Actinobacteria,4D07Y@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BHPHKHDA_01671 326426.Bbr_1215 1.49e-176 492.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4D06Q@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01672 216816.GS08_06340 4.2e-139 393.0 COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4D0ZC@85004|Bifidobacteriales 201174|Actinobacteria K Virulence activator alpha C-term - - - - - - - - - - - - PadR,Vir_act_alpha_C BHPHKHDA_01673 326426.Bbr_1213 0.0 1266.0 COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4CYX3@85004|Bifidobacteriales 201174|Actinobacteria T Elongation factor G C-terminus typA - - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 BHPHKHDA_01674 326426.Bbr_1212 5.73e-101 295.0 2E9EF@1|root,333MW@2|Bacteria,2IKWQ@201174|Actinobacteria,4D10T@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01675 326426.Bbr_1211 1.41e-241 662.0 COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CZ61@85004|Bifidobacteriales 201174|Actinobacteria E Prephenate dehydratase pheA - 4.2.1.51,5.4.99.5 ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715 RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - - ACT,PDT BHPHKHDA_01676 326426.Bbr_1210 1.36e-242 666.0 COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CYV2@85004|Bifidobacteriales 201174|Actinobacteria E Prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH BHPHKHDA_01677 326426.Bbr_1209 9.63e-56 173.0 2BGJ3@1|root,32AHC@2|Bacteria,2IR91@201174|Actinobacteria,4D17H@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01678 326426.Bbr_1208 0.0 1622.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,4CZIE@85004|Bifidobacteriales 201174|Actinobacteria MV MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD BHPHKHDA_01679 326426.Bbr_1207 7.44e-190 527.0 COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CZ04@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01680 326426.Bbr_1206 2.96e-242 665.0 COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZCX@85004|Bifidobacteriales 201174|Actinobacteria D Belongs to the 'phage' integrase family. XerC subfamily xerC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase BHPHKHDA_01681 326426.Bbr_1205 0.0 1069.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 201174|Actinobacteria E ABC transporter, substrate-binding protein, family 5 dppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 BHPHKHDA_01682 326426.Bbr_1204 1.39e-204 568.0 COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CZSV@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component dppB - - ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 BHPHKHDA_01683 326426.Bbr_1203 2.12e-228 630.0 COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales 201174|Actinobacteria EP N-terminal TM domain of oligopeptide transport permease C dppC - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N BHPHKHDA_01684 216816.GS08_06290 0.0 1283.0 COG0444@1|root,COG1123@1|root,COG0444@2|Bacteria,COG4172@2|Bacteria,2GIXV@201174|Actinobacteria,4D2V0@85004|Bifidobacteriales 201174|Actinobacteria EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY BHPHKHDA_01685 326426.Bbr_1201 1.13e-217 599.0 COG0708@1|root,COG0708@2|Bacteria,2GKIS@201174|Actinobacteria,4CYVB@85004|Bifidobacteriales 201174|Actinobacteria L Endonuclease/Exonuclease/phosphatase family xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos BHPHKHDA_01686 326426.Bbr_1200 3.99e-195 541.0 28J4D@1|root,30NZ9@2|Bacteria,2I2E9@201174|Actinobacteria,4D2VD@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3710) - - - - - - - - - - - - DUF3710 BHPHKHDA_01687 326426.Bbr_1199 2.99e-174 487.0 2AVV0@1|root,31MNQ@2|Bacteria,2GJKP@201174|Actinobacteria,4CYQX@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3159) - - - - - - - - - - - - DUF3159 BHPHKHDA_01688 326426.Bbr_1198 1.86e-306 835.0 COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,4CYYN@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr BHPHKHDA_01689 326426.Bbr_1197 5.29e-127 362.0 2AVVG@1|root,31MP9@2|Bacteria,2INFG@201174|Actinobacteria,4D12J@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - Peripla_BP_4 BHPHKHDA_01690 326426.Bbr_1196 0.0 1625.0 COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4CYS1@85004|Bifidobacteriales 201174|Actinobacteria P E1-E2 ATPase ctpE GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase BHPHKHDA_01691 326426.Bbr_1195 0.0 1800.0 COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4CZ3T@85004|Bifidobacteriales 201174|Actinobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C BHPHKHDA_01692 326426.Bbr_1194 6.43e-153 429.0 COG1246@1|root,COG1246@2|Bacteria,2I61X@201174|Actinobacteria,4D2U1@85004|Bifidobacteriales 201174|Actinobacteria E Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Acetyltransf_1 BHPHKHDA_01693 326426.Bbr_1193 1.86e-105 307.0 COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria,4CZRF@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg,Sigma70_r4_2 BHPHKHDA_01694 326426.Bbr_1192 2.33e-174 488.0 COG0670@1|root,COG0670@2|Bacteria,2I98Y@201174|Actinobacteria,4CZIJ@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the BI1 family - - - ko:K06890 - - - - ko00000 - - - Bax1-I BHPHKHDA_01695 326426.Bbr_1191 3.21e-211 585.0 COG0697@1|root,COG0697@2|Bacteria,2I8X5@201174|Actinobacteria,4D0BH@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA BHPHKHDA_01696 326426.Bbr_1190 6.23e-186 518.0 COG2357@1|root,COG2357@2|Bacteria,2GKF8@201174|Actinobacteria,4CYXP@85004|Bifidobacteriales 201174|Actinobacteria S Region found in RelA / SpoT proteins ywaC - 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT BHPHKHDA_01697 326426.Bbr_1189 0.0 952.0 COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CZFB@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 BHPHKHDA_01698 326426.Bbr_1188 3.38e-226 624.0 COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CZNS@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT BHPHKHDA_01699 326426.Bbr_1187 3.87e-193 536.0 COG2184@1|root,COG2184@2|Bacteria,2IN0D@201174|Actinobacteria,4D03T@85004|Bifidobacteriales 201174|Actinobacteria D Fic/DOC family fic - - ko:K04095 - - - - ko00000,ko03036 - - - Fic BHPHKHDA_01700 326426.Bbr_1186 0.0 1772.0 COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CZ5T@85004|Bifidobacteriales 201174|Actinobacteria D FtsK SpoIIIE family protein ftsK GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma BHPHKHDA_01701 326426.Bbr_1185 4.89e-152 427.0 COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CZ36@85004|Bifidobacteriales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf BHPHKHDA_01702 326426.Bbr_1184 1.54e-124 355.0 COG1546@1|root,COG1546@2|Bacteria,2IQ8T@201174|Actinobacteria,4D0CM@85004|Bifidobacteriales 201174|Actinobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA BHPHKHDA_01703 326426.Bbr_1183 2.3e-101 295.0 COG1426@1|root,COG1426@2|Bacteria,2I2G5@201174|Actinobacteria,4D0PT@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_31 BHPHKHDA_01704 326426.Bbr_1182 9.29e-52 163.0 2EFU9@1|root,339KE@2|Bacteria,2GQJW@201174|Actinobacteria,4D16T@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3046) - - - - - - - - - - - - DUF3046 BHPHKHDA_01705 326426.Bbr_1181 1.29e-261 719.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales 201174|Actinobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA BHPHKHDA_01706 326426.Bbr_1180 1.84e-132 376.0 COG2137@1|root,COG2137@2|Bacteria,2INKM@201174|Actinobacteria,4D0Y4@85004|Bifidobacteriales 201174|Actinobacteria S Modulates RecA activity recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX BHPHKHDA_01707 326426.Bbr_1179 1.24e-154 434.0 COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CZ3H@85004|Bifidobacteriales 201174|Actinobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE BHPHKHDA_01708 326426.Bbr_1178 0.0 1858.0 COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,4CYX6@85004|Bifidobacteriales 201174|Actinobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW BHPHKHDA_01709 326426.Bbr_1177 5.12e-243 668.0 COG0547@1|root,COG0547@2|Bacteria,2GM4G@201174|Actinobacteria,4CZKZ@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 BHPHKHDA_01710 326426.Bbr_1176 1.89e-158 444.0 2AP35@1|root,31E4N@2|Bacteria,2IBUY@201174|Actinobacteria,4D0R7@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01711 326426.Bbr_1175 2.4e-169 473.0 COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4CZBB@85004|Bifidobacteriales 201174|Actinobacteria I Phosphate acyltransferases plsC2 - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase BHPHKHDA_01712 326426.Bbr_1174 0.0 1342.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CYTR@85004|Bifidobacteriales 201174|Actinobacteria KLT PASTA pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase BHPHKHDA_01713 326426.Bbr_1173 1.95e-250 688.0 COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CZQV@85004|Bifidobacteriales 201174|Actinobacteria H Belongs to the FPP GGPP synthase family idsA - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt BHPHKHDA_01714 326426.Bbr_1172 2.58e-141 400.0 2B5AP@1|root,31Y4U@2|Bacteria,2IF9M@201174|Actinobacteria,4D15J@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - DUF4192 BHPHKHDA_01715 326426.Bbr_1171 2.4e-248 692.0 COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CZQC@85004|Bifidobacteriales 201174|Actinobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 BHPHKHDA_01716 326426.Bbr_1170 0.0 1530.0 COG0187@1|root,COG0187@2|Bacteria,2GM1E@201174|Actinobacteria,4CYXR@85004|Bifidobacteriales 201174|Actinobacteria L DNA topoisomerase (ATP-hydrolyzing) gyrB2 - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim BHPHKHDA_01717 326426.Bbr_1169 1.25e-284 778.0 COG0738@1|root,COG0738@2|Bacteria,2HWKN@201174|Actinobacteria,4CYRZ@85004|Bifidobacteriales 201174|Actinobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_01718 326426.Bbr_1168 1.17e-218 604.0 COG0524@1|root,COG0524@2|Bacteria,2I04R@201174|Actinobacteria,4CZIB@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB BHPHKHDA_01719 326426.Bbr_1167 0.0 3133.0 COG1201@1|root,COG1201@2|Bacteria,2GJG3@201174|Actinobacteria,4D01F@85004|Bifidobacteriales 201174|Actinobacteria L DEAD DEAH box helicase lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,HTH_42,Helicase_C BHPHKHDA_01722 1123075.AUDP01000027_gene676 3.14e-27 114.0 COG4977@1|root,COG4977@2|Bacteria,1UINP@1239|Firmicutes,24PQ6@186801|Clostridia,3WSSR@541000|Ruminococcaceae 186801|Clostridia K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC BHPHKHDA_01723 1713.JOFV01000003_gene1654 7.07e-127 381.0 COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria,4F27I@85016|Cellulomonadaceae 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 BHPHKHDA_01724 326426.Bbr_1162 0.0 1744.0 COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CYVH@85004|Bifidobacteriales 201174|Actinobacteria L DNA topoisomerase (ATP-hydrolyzing) gyrA2 - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV BHPHKHDA_01725 326426.Bbr_1161 7.3e-299 815.0 COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,4CZCK@85004|Bifidobacteriales 201174|Actinobacteria S Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest BHPHKHDA_01726 326426.Bbr_1160 2.05e-210 587.0 29W72@1|root,30HS9@2|Bacteria,2HZB4@201174|Actinobacteria,4CZFJ@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3071) - - - - - - - - - - - - DUF3071 BHPHKHDA_01727 326426.Bbr_1159 4.95e-63 192.0 2ATJW@1|root,3361K@2|Bacteria,2I80Y@201174|Actinobacteria,4D10Y@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4193) - - - - - - - - - - - - DUF4193 BHPHKHDA_01728 326426.Bbr_1158 2.39e-108 312.0 COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CZUJ@85004|Bifidobacteriales 201174|Actinobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase BHPHKHDA_01729 326426.Bbr_1157 0.0 1518.0 COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CZCW@85004|Bifidobacteriales 201174|Actinobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS BHPHKHDA_01730 326426.Bbr_1156 8.07e-133 375.0 COG0652@1|root,COG0652@2|Bacteria,2IFUE@201174|Actinobacteria,4CZSU@85004|Bifidobacteriales 201174|Actinobacteria G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase BHPHKHDA_01731 216816.GS08_05970 1.31e-98 285.0 2ATF2@1|root,31IYI@2|Bacteria,2IIKG@201174|Actinobacteria,4D0ZG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01733 326426.Bbr_1154 7.8e-299 817.0 COG3550@1|root,COG3550@2|Bacteria,2IEM1@201174|Actinobacteria,4CZPH@85004|Bifidobacteriales 201174|Actinobacteria S HipA-like C-terminal domain - - - - - - - - - - - - HipA_C BHPHKHDA_01734 547043.BIFPSEUDO_03929 6.44e-64 201.0 COG2189@1|root,COG2189@2|Bacteria 2|Bacteria L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase BHPHKHDA_01736 547043.BIFPSEUDO_03926 1.53e-35 120.0 2B0NT@1|root,31T0I@2|Bacteria,2GRGK@201174|Actinobacteria,4D1EC@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01737 547043.BIFPSEUDO_03925 3.41e-183 509.0 COG2184@1|root,COG2184@2|Bacteria,2IN0D@201174|Actinobacteria,4D03T@85004|Bifidobacteriales 201174|Actinobacteria D Fic/DOC family fic - - ko:K04095 - - - - ko00000,ko03036 - - - Fic BHPHKHDA_01739 1437600.JDUI01000024_gene1209 4.26e-62 194.0 COG2801@1|root,COG2801@2|Bacteria,2I8Z0@201174|Actinobacteria,4D0BU@85004|Bifidobacteriales 201174|Actinobacteria L Integrase core domain - - - - - - - - - - - - rve BHPHKHDA_01740 216816.GS08_04250 1.93e-61 203.0 COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4D2W9@85004|Bifidobacteriales 201174|Actinobacteria EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_3 BHPHKHDA_01741 326426.Bbr_1655 9.5e-311 843.0 COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4CYPX@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 1 - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 BHPHKHDA_01742 326426.Bbr_1656 7.21e-205 567.0 COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4CZQ9@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02026,ko:K10190 ko02010,map02010 M00199,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.4 - - BPD_transp_1 BHPHKHDA_01743 326426.Bbr_1657 1.99e-207 575.0 COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4CZDV@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_01744 326426.Bbr_1658 2.11e-309 843.0 COG1653@1|root,COG1653@2|Bacteria,2GM4E@201174|Actinobacteria,4CZ8S@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027,ko:K10227 ko02010,map02010 M00200,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.5 - - SBP_bac_1,SBP_bac_8 BHPHKHDA_01745 326426.Bbr_1659 6.09e-276 754.0 COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4D04H@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 BHPHKHDA_01746 326426.Bbr_1660 4.86e-29 105.0 2B4WM@1|root,31XPC@2|Bacteria,2GZCV@201174|Actinobacteria,4D1TG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01748 216816.GS08_09170 2.11e-77 239.0 COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4D03A@85004|Bifidobacteriales 201174|Actinobacteria S EamA-like transporter family - - - ko:K11939 - - - - ko00000,ko02000 2.A.7.3.6 - - EamA BHPHKHDA_01749 216816.GS08_09170 6.07e-27 106.0 COG5006@1|root,COG5006@2|Bacteria,2GJKB@201174|Actinobacteria,4D03A@85004|Bifidobacteriales 201174|Actinobacteria S EamA-like transporter family - - - ko:K11939 - - - - ko00000,ko02000 2.A.7.3.6 - - EamA BHPHKHDA_01750 326426.Bbr_1662 3.9e-299 817.0 COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CZHT@85004|Bifidobacteriales 201174|Actinobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - HHH_5,IMS,IMS_C,IMS_HHH BHPHKHDA_01751 326426.Bbr_1663 2.83e-282 771.0 COG0436@1|root,COG0436@2|Bacteria,2GJMI@201174|Actinobacteria,4CZ91@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class I and II dapC - - - - - - - - - - - Aminotran_1_2 BHPHKHDA_01752 326426.Bbr_1664 4.51e-79 234.0 COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4D11B@85004|Bifidobacteriales 201174|Actinobacteria C 4Fe-4S binding domain fdxA GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - ko:K05524 - - - - ko00000 - - - Fer4 BHPHKHDA_01753 326426.Bbr_1665 0.0 952.0 COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4CYZA@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 BHPHKHDA_01754 326426.Bbr_1666 4e-279 764.0 COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,4CZSJ@85004|Bifidobacteriales 201174|Actinobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C BHPHKHDA_01755 1437609.BCAL_1264 1.03e-34 118.0 COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4D1EA@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal protein L33 rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 BHPHKHDA_01759 326426.Bbr_1668 1.73e-63 194.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales 201174|Actinobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 BHPHKHDA_01760 326426.Bbr_1669 1.32e-183 519.0 2E03N@1|root,32VSG@2|Bacteria,2GQE4@201174|Actinobacteria,4CYUX@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01761 326426.Bbr_1670 2.1e-112 323.0 COG1670@1|root,COG1670@2|Bacteria,2HAFI@201174|Actinobacteria,4CZRR@85004|Bifidobacteriales 201174|Actinobacteria J Acetyltransferase (GNAT) domain rimJ - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 BHPHKHDA_01762 216816.GS08_09245 2.06e-78 241.0 COG0212@1|root,COG0212@2|Bacteria,2IKWR@201174|Actinobacteria,4D12B@85004|Bifidobacteriales 201174|Actinobacteria H 5-formyltetrahydrofolate cyclo-ligase family ygfA - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig BHPHKHDA_01763 326426.Bbr_1670a 6.24e-43 139.0 COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4D1ES@85004|Bifidobacteriales 201174|Actinobacteria S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 BHPHKHDA_01764 326426.Bbr_1672 5.63e-137 389.0 COG1261@1|root,COG1261@2|Bacteria,2IIYF@201174|Actinobacteria,4D0YD@85004|Bifidobacteriales 201174|Actinobacteria NO SAF - - - - - - - - - - - - ChapFlgA,SAF BHPHKHDA_01765 1437610.BREU_0572 8.07e-34 128.0 COG1112@1|root,COG1112@2|Bacteria,2GKJW@201174|Actinobacteria,4CYY9@85004|Bifidobacteriales 201174|Actinobacteria L Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 BHPHKHDA_01766 326426.Bbr_1673 0.0 2323.0 COG1112@1|root,COG1112@2|Bacteria,2GKJW@201174|Actinobacteria,4CYY9@85004|Bifidobacteriales 201174|Actinobacteria L Superfamily I DNA and RNA helicases and helicase subunits - - - - - - - - - - - - AAA_11,AAA_12,DUF4011 BHPHKHDA_01767 326426.Bbr_1674 2.22e-273 754.0 COG1716@1|root,COG1716@2|Bacteria,2GIT6@201174|Actinobacteria,4CYX9@85004|Bifidobacteriales 201174|Actinobacteria T Forkhead associated domain - - - - - - - - - - - - FHA BHPHKHDA_01768 326426.Bbr_1675 1.06e-73 222.0 COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4D0W2@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N BHPHKHDA_01769 326426.Bbr_1676 2.41e-113 326.0 COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4CZFP@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 BHPHKHDA_01770 326426.Bbr_1677 5.66e-186 517.0 COG1073@1|root,COG1073@2|Bacteria,2HZF3@201174|Actinobacteria,4D06X@85004|Bifidobacteriales 201174|Actinobacteria S alpha beta - - - - - - - - - - - - - BHPHKHDA_01771 326426.Bbr_1678 0.0 874.0 COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4CZHD@85004|Bifidobacteriales 201174|Actinobacteria S Permease family - - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease BHPHKHDA_01772 326426.Bbr_1679 1.57e-190 528.0 COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4CYVE@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran BHPHKHDA_01773 326426.Bbr_1680 1.86e-221 612.0 COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria,4D2UW@85004|Bifidobacteriales 201174|Actinobacteria P Phosphate transport system permease pstA - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 BHPHKHDA_01774 326426.Bbr_1681 6.67e-212 587.0 COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria,4CYV0@85004|Bifidobacteriales 201174|Actinobacteria P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 BHPHKHDA_01775 326426.Bbr_1682 2.32e-260 714.0 COG0226@1|root,COG0226@2|Bacteria,2GJXD@201174|Actinobacteria,4CYTZ@85004|Bifidobacteriales 201174|Actinobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import pstS - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 BHPHKHDA_01776 326426.Bbr_1683 1.5e-182 508.0 COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CZTX@85004|Bifidobacteriales 201174|Actinobacteria KT Transcriptional regulatory protein, C terminal regX3 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - ko:K07776 ko02020,map02020 M00443 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C BHPHKHDA_01777 326426.Bbr_1684 1.14e-276 761.0 COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CZ42@85004|Bifidobacteriales 201174|Actinobacteria T His Kinase A (phosphoacceptor) domain phoR - 2.7.13.3 ko:K07636,ko:K07768 ko02020,map02020 M00434,M00443 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4 BHPHKHDA_01778 326426.Bbr_1685 7.6e-305 832.0 COG0477@1|root,COG0477@2|Bacteria,2GIYR@201174|Actinobacteria,4CZFF@85004|Bifidobacteriales 201174|Actinobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr BHPHKHDA_01779 326426.Bbr_1686 2.11e-159 447.0 COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4CYTM@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 BHPHKHDA_01780 326426.Bbr_1687 9.45e-300 817.0 COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZ7I@85004|Bifidobacteriales 201174|Actinobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 BHPHKHDA_01781 326426.Bbr_1688 2.3e-277 758.0 COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CZMR@85004|Bifidobacteriales 201174|Actinobacteria E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 BHPHKHDA_01782 326426.Bbr_1689 1.97e-111 320.0 COG2731@1|root,COG2731@2|Bacteria,2GQ7V@201174|Actinobacteria,4D2GP@85004|Bifidobacteriales 201174|Actinobacteria G YhcH YjgK YiaL family protein - - - ko:K12112 ko00052,ko00511,ko01100,map00052,map00511,map01100 - R01678 RC00049 ko00000,ko00001 - - - - BHPHKHDA_01783 326426.Bbr_1690 0.0 2210.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 201174|Actinobacteria G Psort location Cytoplasmic, score 8.87 - - 3.2.1.23 ko:K12111 ko00052,ko00511,ko01100,map00052,map00511,map01100 - R01678,R06114 RC00049 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N BHPHKHDA_01784 326426.Bbr_1691 6.14e-147 414.0 COG0637@1|root,COG0637@2|Bacteria 2|Bacteria S phosphonoacetaldehyde hydrolase activity pgmB - 5.4.2.6 ko:K01838,ko:K04844 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2 BHPHKHDA_01785 326426.Bbr_1692 6.58e-200 555.0 COG0697@1|root,COG0697@2|Bacteria,2HNPV@201174|Actinobacteria,4D04C@85004|Bifidobacteriales 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA BHPHKHDA_01786 326426.Bbr_1693 0.0 1585.0 COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4D0DE@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolase family 65 central catalytic domain kojP - 2.4.1.230,2.4.1.64 ko:K05342,ko:K10231 ko00500,ko01100,map00500,map01100 - R02727 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2 BHPHKHDA_01787 326426.Bbr_1694 1.51e-195 542.0 COG0395@1|root,COG0395@2|Bacteria,2GJNJ@201174|Actinobacteria,4D0WS@85004|Bifidobacteriales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_01788 326426.Bbr_1695 5.76e-216 597.0 COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4CZDV@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 BHPHKHDA_01789 326426.Bbr_1696 2.04e-303 827.0 COG1653@1|root,COG1653@2|Bacteria,2HEH9@201174|Actinobacteria,4D1JK@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1 BHPHKHDA_01790 326426.Bbr_1697 1.59e-241 664.0 COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4CZUG@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_01791 326426.Bbr_1698 1.41e-127 364.0 COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria,4D0ZV@85004|Bifidobacteriales 201174|Actinobacteria U MarC family integral membrane protein - - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC BHPHKHDA_01792 326426.Bbr_1699 0.0 904.0 COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria,4CZDZ@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase C1-like family pepC2 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 BHPHKHDA_01793 326426.Bbr_1700 0.0 920.0 COG3579@1|root,COG3579@2|Bacteria,2GNYU@201174|Actinobacteria,4CZDZ@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase C1-like family pepC2 - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 BHPHKHDA_01794 326426.Bbr_1701 6.94e-120 366.0 COG1196@1|root,COG1196@2|Bacteria,2HZ99@201174|Actinobacteria,4CZ0S@85004|Bifidobacteriales 201174|Actinobacteria D nuclear chromosome segregation - - - - - - - - - - - - DivIVA BHPHKHDA_01795 326426.Bbr_1702 6.14e-162 453.0 COG2039@1|root,COG2039@2|Bacteria,2GN39@201174|Actinobacteria,4CZ57@85004|Bifidobacteriales 201174|Actinobacteria O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp - 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 BHPHKHDA_01796 326426.Bbr_1703 1.56e-192 535.0 COG1211@1|root,COG1211@2|Bacteria,2GNHP@201174|Actinobacteria,4CYVZ@85004|Bifidobacteriales 201174|Actinobacteria I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD - 1.1.1.405,2.7.7.40,2.7.7.60 ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 M00096 R01525,R02921,R05633 RC00002,RC00089 ko00000,ko00001,ko00002,ko01000 - - - IspD,adh_short BHPHKHDA_01797 326426.Bbr_1704 5.84e-252 691.0 COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4CZBI@85004|Bifidobacteriales 201174|Actinobacteria Q Multi-copper polyphenol oxidoreductase laccase yfiH GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 BHPHKHDA_01798 326426.Bbr_1705 0.0 1032.0 COG0826@1|root,COG0826@2|Bacteria,2GKTB@201174|Actinobacteria,4CZA1@85004|Bifidobacteriales 201174|Actinobacteria O Peptidase family U32 C-terminal domain - - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C BHPHKHDA_01799 326426.Bbr_1706 2.38e-225 621.0 COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4CZ7A@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - Acetyltransf_1,tRNA_m1G_MT BHPHKHDA_01800 326426.Bbr_1707 1.17e-132 376.0 COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4D0GU@85004|Bifidobacteriales 201174|Actinobacteria L Conserved hypothetical protein 95 rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 BHPHKHDA_01801 326426.Bbr_1708 0.0 1465.0 COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CYTV@85004|Bifidobacteriales 201174|Actinobacteria L helicase superfamily c-terminal domain recG GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge,tRNA_anti-codon BHPHKHDA_01802 326426.Bbr_1709 1.05e-40 134.0 COG0227@1|root,COG0227@2|Bacteria,2GQNU@201174|Actinobacteria,4D17Q@85004|Bifidobacteriales 201174|Actinobacteria J Ribosomal L28 family rpmB GO:0003674,GO:0003735,GO:0005198 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 BHPHKHDA_01803 326426.Bbr_1710 2.02e-246 676.0 COG0524@1|root,COG0524@2|Bacteria,2IA3T@201174|Actinobacteria,4CYSM@85004|Bifidobacteriales 201174|Actinobacteria G pfkB family carbohydrate kinase - - - - - - - - - - - - ADP_ribosyl_GH,PfkB BHPHKHDA_01804 326426.Bbr_1711 7.26e-302 824.0 COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,4CZU3@85004|Bifidobacteriales 201174|Actinobacteria S Vacuole effluxer Atg22 like - - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 BHPHKHDA_01805 216816.GS08_01650 2.28e-168 471.0 COG0789@1|root,COG0789@2|Bacteria,2HZI3@201174|Actinobacteria,4D0I1@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 BHPHKHDA_01806 216816.GS08_01645 3.59e-82 243.0 COG2337@1|root,COG2337@2|Bacteria,2IFQF@201174|Actinobacteria,4D0PF@85004|Bifidobacteriales 201174|Actinobacteria T Toxic component of a toxin-antitoxin (TA) module - - - - - - - - - - - - - BHPHKHDA_01807 398513.BBNG_00218 2.07e-71 214.0 COG3077@1|root,COG3077@2|Bacteria,2IJU2@201174|Actinobacteria,4D0WU@85004|Bifidobacteriales 201174|Actinobacteria L RelB antitoxin - - - - - - - - - - - - RelB BHPHKHDA_01808 216816.GS08_01635 1.49e-30 108.0 COG2270@1|root,COG2270@2|Bacteria 2|Bacteria G Major facilitator Superfamily yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 BHPHKHDA_01809 326426.Bbr_1716 1.41e-244 673.0 COG1476@1|root,COG1476@2|Bacteria,2IBHI@201174|Actinobacteria,4CZ2T@85004|Bifidobacteriales 201174|Actinobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 BHPHKHDA_01810 216816.GS08_01625 1.28e-12 65.1 2BSWU@1|root,32N0G@2|Bacteria,2HA44@201174|Actinobacteria,4D2Q5@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01814 1437610.BREU_0523 1.01e-58 186.0 COG0431@1|root,COG0431@2|Bacteria,2GMA7@201174|Actinobacteria,4D163@85004|Bifidobacteriales 201174|Actinobacteria S NADPH-dependent FMN reductase - - - ko:K19784 - - - - ko00000 - - - FMN_red BHPHKHDA_01815 326426.Bbr_1719 0.0 6002.0 COG0304@1|root,COG0331@1|root,COG2030@1|root,COG4981@1|root,COG0304@2|Bacteria,COG0331@2|Bacteria,COG2030@2|Bacteria,COG4981@2|Bacteria,2GIY4@201174|Actinobacteria,4CYXJ@85004|Bifidobacteriales 201174|Actinobacteria I Beta-ketoacyl synthase, C-terminal domain fas - - ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 M00082,M00083 R01624,R01626,R04355,R04428,R04429,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04724,R04726,R04952,R04953,R04954,R04955,R04957,R04958,R04960,R04961,R04963,R04964,R04965,R04966,R04968,R04969,R07762,R07763,R07764,R07765,R10700 RC00004,RC00029,RC00039,RC00052,RC00076,RC00117,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1,DUF1729,Ketoacyl-synt_C,MaoC_dehydratas,SAT,ketoacyl-synt BHPHKHDA_01816 326426.Bbr_1720 0.0 1033.0 COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CYSI@85004|Bifidobacteriales 201174|Actinobacteria I Carboxyl transferase domain pccB - - - - - - - - - - - Carboxyl_trans BHPHKHDA_01817 326426.Bbr_1721 0.0 1215.0 COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4CYU4@85004|Bifidobacteriales 201174|Actinobacteria I Carbamoyl-phosphate synthase L chain, ATP binding domain protein accC - 6.3.4.14,6.4.1.2,6.4.1.3 ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00741 R00742,R01859,R04385 RC00040,RC00097,RC00253,RC00367,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 BHPHKHDA_01819 326426.Bbr_1722 1.6e-117 338.0 COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4D0BB@85004|Bifidobacteriales 201174|Actinobacteria S BioY family bioY - - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY BHPHKHDA_01820 326426.Bbr_1723 3.7e-209 579.0 COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4D0R8@85004|Bifidobacteriales 201174|Actinobacteria H Biotin/lipoate A/B protein ligase family birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB BHPHKHDA_01821 326426.Bbr_1724 0.0 1364.0 2DX0J@1|root,342TV@2|Bacteria,2H683@201174|Actinobacteria,4CZAG@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01822 326426.Bbr_1725 7.54e-211 583.0 COG2508@1|root,COG2508@2|Bacteria,2GN0S@201174|Actinobacteria,4CYXU@85004|Bifidobacteriales 201174|Actinobacteria QT PucR C-terminal helix-turn-helix domain - - - - - - - - - - - - HTH_30 BHPHKHDA_01823 326426.Bbr_1726 1.75e-159 447.0 COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CZFR@85004|Bifidobacteriales 201174|Actinobacteria J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 BHPHKHDA_01824 216816.GS08_09450 2.9e-95 278.0 COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4D0PA@85004|Bifidobacteriales 201174|Actinobacteria J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N BHPHKHDA_01825 762211.BSTEL_2229 6.32e-55 171.0 2B78R@1|root,320BB@2|Bacteria,2IQGT@201174|Actinobacteria,4D178@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01826 326426.Bbr_1852 0.0 1113.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ2A@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 BHPHKHDA_01827 326426.Bbr_1851 0.0 1351.0 COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4CZ9R@85004|Bifidobacteriales 201174|Actinobacteria S YhgE Pip domain protein - - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 BHPHKHDA_01828 326426.Bbr_1850 1.05e-177 495.0 COG0778@1|root,COG0778@2|Bacteria,2I65Z@201174|Actinobacteria,4CZ5R@85004|Bifidobacteriales 201174|Actinobacteria C Nitroreductase family nfrA - - - - - - - - - - - Nitroreductase BHPHKHDA_01829 326426.Bbr_1849 6.43e-79 235.0 2B5DJ@1|root,31Y80@2|Bacteria,2IRRR@201174|Actinobacteria,4D1E6@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF4235) - - - - - - - - - - - - DUF4235 BHPHKHDA_01830 326426.Bbr_1848 1.29e-132 377.0 COG0406@1|root,COG0406@2|Bacteria,2GNRS@201174|Actinobacteria,4CZD2@85004|Bifidobacteriales 201174|Actinobacteria G Phosphoglycerate mutase family gpm2 GO:0003674,GO:0003824,GO:0003993,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0042802,GO:0042803,GO:0044237,GO:0046983 3.1.3.73 ko:K02226 ko00860,ko01100,map00860,map01100 M00122 R04594,R11173 RC00017 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 BHPHKHDA_01831 326426.Bbr_1847 0.0 884.0 COG1653@1|root,COG1653@2|Bacteria,2GWCY@201174|Actinobacteria,4CYWG@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein amyE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 BHPHKHDA_01832 326426.Bbr_1846 1.4e-235 649.0 COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria,4CZ1Y@85004|Bifidobacteriales 201174|Actinobacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_01833 326426.Bbr_1845 3.3e-200 555.0 COG1175@1|root,COG1175@2|Bacteria,2I330@201174|Actinobacteria,4CZJC@85004|Bifidobacteriales 201174|Actinobacteria G Binding-protein-dependent transport system inner membrane component msmF - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_01834 326426.Bbr_1844 4.49e-196 544.0 COG0395@1|root,COG0395@2|Bacteria,2GJNN@201174|Actinobacteria,4CYZ9@85004|Bifidobacteriales 201174|Actinobacteria G ABC transporter permease - - - ko:K02026,ko:K10119 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_01835 326426.Bbr_1843 9.49e-136 385.0 COG5578@1|root,COG5578@2|Bacteria,2IBKF@201174|Actinobacteria,4D0E0@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function, DUF624 - - - - - - - - - - - - DUF624 BHPHKHDA_01836 326426.Bbr_1842 0.0 933.0 COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZ4X@85004|Bifidobacteriales 201174|Actinobacteria E aromatic amino acid transport protein AroP K03293 aroP - - ko:K03293,ko:K11732 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.1 - - AA_permease BHPHKHDA_01837 326426.Bbr_1841 1.76e-165 462.0 COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4CYT2@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01838 326426.Bbr_1840 0.0 1870.0 COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,2I2FK@201174|Actinobacteria,4CZJR@85004|Bifidobacteriales 201174|Actinobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX BHPHKHDA_01839 326426.Bbr_1839 0.0 957.0 COG1113@1|root,COG1113@2|Bacteria,2GJ0X@201174|Actinobacteria,4CZAY@85004|Bifidobacteriales 201174|Actinobacteria E Amino acid permease - - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease BHPHKHDA_01840 326426.Bbr_1828 8.11e-121 345.0 COG1846@1|root,COG1846@2|Bacteria,2IMKE@201174|Actinobacteria,4CYZZ@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - HTH_34,MarR BHPHKHDA_01841 326426.Bbr_1827 0.0 1136.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CYYV@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter, ATP-binding protein - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BHPHKHDA_01842 326426.Bbr_1826 0.0 1162.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZTU@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter transmembrane region - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BHPHKHDA_01843 326426.Bbr_1825 4.14e-229 630.0 COG1477@1|root,COG1477@2|Bacteria,2H8YU@201174|Actinobacteria,4CZW7@85004|Bifidobacteriales 201174|Actinobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE BHPHKHDA_01844 326426.Bbr_1824 0.0 895.0 COG2211@1|root,COG2211@2|Bacteria,2HZ98@201174|Actinobacteria,4CZ0N@85004|Bifidobacteriales 201174|Actinobacteria G MFS/sugar transport protein - - - - - - - - - - - - MFS_2 BHPHKHDA_01846 326426.Bbr_1823 8.72e-235 647.0 COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CZ03@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase BHPHKHDA_01847 326426.Bbr_1821 5.33e-156 437.0 2AU2N@1|root,31JNZ@2|Bacteria,2IJNI@201174|Actinobacteria,4D047@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01848 216816.GS08_10075 0.0 1189.0 COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CZ20@85004|Bifidobacteriales 201174|Actinobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g BHPHKHDA_01849 326426.Bbr_1819 2.02e-62 191.0 2AWD6@1|root,31N94@2|Bacteria,2IP9F@201174|Actinobacteria,4D137@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01850 216816.GS08_10060 0.0 991.0 COG3579@1|root,COG3579@2|Bacteria,2HCVR@201174|Actinobacteria,4CZD8@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase C1-like family - - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 BHPHKHDA_01851 216816.GS08_10055 3.53e-228 629.0 COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CYS5@85004|Bifidobacteriales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component oppB1 - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 BHPHKHDA_01852 326426.Bbr_1816 8.61e-227 626.0 COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4CYQF@85004|Bifidobacteriales 201174|Actinobacteria EP N-terminal TM domain of oligopeptide transport permease C oppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N BHPHKHDA_01853 216816.GS08_10045 0.0 1380.0 COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4CYU0@85004|Bifidobacteriales 201174|Actinobacteria P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY BHPHKHDA_01854 326426.Bbr_1814 0.0 1104.0 COG0747@1|root,COG0747@2|Bacteria,2GJ9N@201174|Actinobacteria,4CZ3S@85004|Bifidobacteriales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle oppA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 BHPHKHDA_01855 1437610.BREU_2284 2.41e-44 148.0 COG0477@1|root,COG0477@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 BHPHKHDA_01856 1437610.BREU_2284 1.48e-71 219.0 COG0477@1|root,COG0477@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 BHPHKHDA_01857 216816.GS08_10030 0.0 918.0 COG1373@1|root,COG1373@2|Bacteria,2HCYQ@201174|Actinobacteria,4D2TP@85004|Bifidobacteriales 201174|Actinobacteria S AAA domain - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_01858 216816.GS08_10025 0.0 1423.0 COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4CZ6K@85004|Bifidobacteriales 201174|Actinobacteria G Beta-galactosidase trimerisation domain - - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M BHPHKHDA_01859 216816.GS08_10020 5.81e-249 683.0 COG1609@1|root,COG1609@2|Bacteria,2GJ5Q@201174|Actinobacteria,4D041@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn _helix lactose operon repressor - - - - - - - - - - - - LacI,Peripla_BP_3 BHPHKHDA_01860 216816.GS08_10015 9.99e-309 840.0 COG1653@1|root,COG1653@2|Bacteria,2HZAD@201174|Actinobacteria,4CZ9S@85004|Bifidobacteriales 201174|Actinobacteria G Bacterial extracellular solute-binding protein - - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_8 BHPHKHDA_01861 1437610.BREU_2296 3.14e-227 626.0 COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4CZCI@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10118 ko02010,map02010 M00196,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_01862 1437610.BREU_2297 3.67e-196 545.0 COG0395@1|root,COG0395@2|Bacteria,2GM2W@201174|Actinobacteria,4D05E@85004|Bifidobacteriales 201174|Actinobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 BHPHKHDA_01863 216816.GS08_10000 7.96e-243 665.0 COG3507@1|root,COG3507@2|Bacteria,2I2H2@201174|Actinobacteria,4CZDP@85004|Bifidobacteriales 201174|Actinobacteria G Glycosyl hydrolases family 43 - - - - - - - - - - - - Glyco_hydro_43 BHPHKHDA_01864 326426.Bbr_1812 0.0 879.0 COG1373@1|root,COG1373@2|Bacteria,2GM3Y@201174|Actinobacteria,4CZTJ@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4143) - - - ko:K07133 - - - - ko00000 - - - AAA_14,DUF4143 BHPHKHDA_01865 216816.GS08_09990 0.0 926.0 COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria,4CZTD@85004|Bifidobacteriales 201174|Actinobacteria S ATPase domain predominantly from Archaea - - - ko:K06921 - - - - ko00000 - - - ATPase_2,DUF234 BHPHKHDA_01866 326426.Bbr_1811 0.0 1232.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4D028@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BHPHKHDA_01867 326426.Bbr_1810 0.0 1156.0 COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CZ32@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran BHPHKHDA_01868 326426.Bbr_1809 1.92e-237 652.0 COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CYZI@85004|Bifidobacteriales 201174|Actinobacteria L TatD related DNase tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase BHPHKHDA_01869 326426.Bbr_1808 0.0 1543.0 COG3158@1|root,COG3158@2|Bacteria,2GMPQ@201174|Actinobacteria,4CZM3@85004|Bifidobacteriales 201174|Actinobacteria P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans BHPHKHDA_01870 326426.Bbr_1807 4.08e-204 565.0 COG0121@1|root,COG0121@2|Bacteria,2IBFV@201174|Actinobacteria,4CYX2@85004|Bifidobacteriales 201174|Actinobacteria S Glutamine amidotransferase domain - - - - - - - - - - - - GATase_6 BHPHKHDA_01871 326426.Bbr_1806 1.01e-179 500.0 COG2206@1|root,COG2206@2|Bacteria,2GNQR@201174|Actinobacteria,4CYT9@85004|Bifidobacteriales 201174|Actinobacteria T HD domain - - - ko:K06950 - - - - ko00000 - - - HD BHPHKHDA_01872 326426.Bbr_1805 1.88e-243 673.0 COG1136@1|root,COG1136@2|Bacteria,2GNFW@201174|Actinobacteria,4CZAW@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01873 326426.Bbr_1804 0.0 899.0 COG0577@1|root,COG0577@2|Bacteria,2GMGJ@201174|Actinobacteria,4CZBN@85004|Bifidobacteriales 201174|Actinobacteria V ABC transporter permease - - - - - - - - - - - - FtsX,MacB_PCD BHPHKHDA_01874 326426.Bbr_1803 1.61e-309 847.0 COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4CZ5B@85004|Bifidobacteriales 201174|Actinobacteria K Cell envelope-related transcriptional attenuator domain yvhJ - - - - - - - - - - - LytR_C,LytR_cpsA_psr BHPHKHDA_01875 326426.Bbr_1802 3.42e-270 759.0 COG0584@1|root,COG3757@1|root,COG0584@2|Bacteria,COG3757@2|Bacteria,2I2GQ@201174|Actinobacteria,4D08Z@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,RicinB_lectin_2,SLH BHPHKHDA_01876 326426.Bbr_1801 6.77e-219 604.0 COG0463@1|root,COG0463@2|Bacteria,2I2GR@201174|Actinobacteria,4CZTN@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 BHPHKHDA_01877 326426.Bbr_1800 0.0 1357.0 28HDP@1|root,2Z7Q8@2|Bacteria,2GNZ3@201174|Actinobacteria,4D0I4@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01878 326426.Bbr_1799 1.39e-261 714.0 COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,4CZZY@85004|Bifidobacteriales 201174|Actinobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3464 GDP_Man_Dehyd BHPHKHDA_01879 326426.Bbr_1798 0.0 988.0 COG1091@1|root,COG1898@1|root,COG1091@2|Bacteria,COG1898@2|Bacteria,2GNY8@201174|Actinobacteria,4CZ18@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133,5.1.3.13 ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777,R06514 RC00182,RC01531 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind,dTDP_sugar_isom BHPHKHDA_01880 326426.Bbr_1797 4.97e-218 601.0 COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4CZ5F@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv0334 NTP_transferase BHPHKHDA_01881 326426.Bbr_1796 7.29e-231 640.0 COG1215@1|root,COG1215@2|Bacteria,2I2H4@201174|Actinobacteria,4D2Y4@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 BHPHKHDA_01882 326426.Bbr_1795 0.0 1362.0 COG3754@1|root,COG3754@2|Bacteria,2HQS4@201174|Actinobacteria,4CYYB@85004|Bifidobacteriales 201174|Actinobacteria M Rhamnan synthesis protein F - - - ko:K07272 - - - - ko00000,ko01000,ko01003,ko01005 - - - Glyco_tran_WbsX,RgpF BHPHKHDA_01883 326426.Bbr_1794 1.44e-192 535.0 COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4CZ73@85004|Bifidobacteriales 201174|Actinobacteria U Transport permease protein tagG - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane BHPHKHDA_01884 326426.Bbr_1793 1.26e-299 817.0 COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4CZ1B@85004|Bifidobacteriales 201174|Actinobacteria GM ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,Wzt_C BHPHKHDA_01885 326426.Bbr_1792 0.0 988.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups lsgC - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 BHPHKHDA_01886 326426.Bbr_1791 0.0 1433.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase BHPHKHDA_01887 326426.Bbr_1790 0.0 1483.0 COG1368@1|root,COG1368@2|Bacteria,2HVID@201174|Actinobacteria,4CZ6J@85004|Bifidobacteriales 201174|Actinobacteria M Psort location CytoplasmicMembrane, score 9.26 - - - - - - - - - - - - Sulfatase BHPHKHDA_01888 326426.Bbr_0151 4.78e-58 185.0 COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4CZRM@85004|Bifidobacteriales 201174|Actinobacteria L IstB-like ATP binding protein istB - - - - - - - - - - - IstB_IS21 BHPHKHDA_01891 326426.Bbr_1506 0.0 904.0 COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4D016@85004|Bifidobacteriales 201174|Actinobacteria M Mycolic acid cyclopropane synthetase cfa GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS BHPHKHDA_01892 326426.Bbr_1505 7.05e-270 739.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CZ71@85004|Bifidobacteriales 201174|Actinobacteria C Iron-containing alcohol dehydrogenase fucO - 1.1.1.77,1.1.99.37,1.2.98.1 ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 - R00614,R01781,R02257 RC00034,RC00087,RC00099,RC00188 ko00000,ko00001,ko01000 - - - Fe-ADH BHPHKHDA_01893 326426.Bbr_1504 1.09e-226 624.0 COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,4CZ7E@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 BHPHKHDA_01894 326426.Bbr_1503 0.0 978.0 COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CZD1@85004|Bifidobacteriales 201174|Actinobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport BHPHKHDA_01895 326426.Bbr_1502 5.88e-297 810.0 COG1215@1|root,COG1215@2|Bacteria,2HZ9V@201174|Actinobacteria,4CZ5J@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3 BHPHKHDA_01896 326426.Bbr_1501 4.06e-246 677.0 COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4CZ0Q@85004|Bifidobacteriales 201174|Actinobacteria V ATPases associated with a variety of cellular activities natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran BHPHKHDA_01897 326426.Bbr_1500 0.0 1032.0 2BWH2@1|root,2Z89R@2|Bacteria,2GMNW@201174|Actinobacteria,4CZP3@85004|Bifidobacteriales 201174|Actinobacteria - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - BHPHKHDA_01898 326426.Bbr_1499 0.0 886.0 COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,4CYXQ@85004|Bifidobacteriales 201174|Actinobacteria M D-Ala-D-Ala carboxypeptidase 3 (S13) family dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 BHPHKHDA_01899 326426.Bbr_1498 1.78e-263 723.0 COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CYSY@85004|Bifidobacteriales 201174|Actinobacteria J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS GO:0008150,GO:0040007 2.4.2.8,6.3.4.19 ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS BHPHKHDA_01900 326426.Bbr_1497 2.66e-126 360.0 COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CZNJ@85004|Bifidobacteriales 201174|Actinobacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran BHPHKHDA_01901 326426.Bbr_1496 0.0 1302.0 COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CZ6U@85004|Bifidobacteriales 201174|Actinobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 BHPHKHDA_01903 216816.GS08_08460 7.27e-139 392.0 COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4CZ5S@85004|Bifidobacteriales 201174|Actinobacteria H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3609c GTP_cyclohydroI BHPHKHDA_01904 216816.GS08_08455 3.57e-203 563.0 COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CZWW@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind BHPHKHDA_01905 216816.GS08_08450 0.0 908.0 COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,2H3G6@201174|Actinobacteria,4D0EJ@85004|Bifidobacteriales 201174|Actinobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folK - 2.7.6.3,4.1.2.25 ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503,R03504 RC00002,RC00017,RC00721,RC00943 ko00000,ko00001,ko00002,ko01000 - - - FolB,HPPK BHPHKHDA_01906 326426.Bbr_1492 2.23e-119 341.0 2DRQG@1|root,33CMQ@2|Bacteria,2HZP6@201174|Actinobacteria,4D14M@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function (DUF3180) - - - - - - - - - - - - DUF3180 BHPHKHDA_01907 216816.GS08_08440 1.48e-216 597.0 COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4CZRC@85004|Bifidobacteriales 201174|Actinobacteria I Thioesterase-like superfamily tesB - - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 BHPHKHDA_01908 216816.GS08_08435 0.0 1115.0 COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,4CYWH@85004|Bifidobacteriales 201174|Actinobacteria S ATP-binding cassette protein, ChvD family yjjK GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - - - - - - - - - - ABC_tran,ABC_tran_Xtn BHPHKHDA_01909 326426.Bbr_1489 0.0 1055.0 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D0BX@85004|Bifidobacteriales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_01911 326426.Bbr_1488 2.48e-227 626.0 COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CZF6@85004|Bifidobacteriales 201174|Actinobacteria G ROK family glkA GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK BHPHKHDA_01912 326426.Bbr_1487 8.08e-117 335.0 COG1846@1|root,COG1846@2|Bacteria,2IHK6@201174|Actinobacteria,4D0T3@85004|Bifidobacteriales 201174|Actinobacteria K Winged helix DNA-binding domain - - - - - - - - - - - - HTH_27,MarR_2 BHPHKHDA_01913 158787.BSCA_2219 9.34e-23 96.7 COG0477@1|root,COG0477@2|Bacteria,2I2QX@201174|Actinobacteria,4CZRY@85004|Bifidobacteriales 201174|Actinobacteria U Major Facilitator Superfamily - - - ko:K08168,ko:K18926 - M00704,M00715 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3.16,2.A.1.3.22,2.A.1.3.30,2.A.1.3.6 - - MFS_1 BHPHKHDA_01914 326426.Bbr_1486 7.01e-210 579.0 COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4CYUN@85004|Bifidobacteriales 201174|Actinobacteria S Oxidoreductase, aldo keto reductase family protein dkg - - - - - - - - - - - Aldo_ket_red BHPHKHDA_01915 326426.Bbr_1485 1.76e-94 275.0 COG0242@1|root,COG0242@2|Bacteria,2IJQ5@201174|Actinobacteria,4D14S@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins fms - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase BHPHKHDA_01916 326426.Bbr_1484 2.4e-187 520.0 2A54I@1|root,30TT6@2|Bacteria,2IETW@201174|Actinobacteria,4CZX3@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01917 326426.Bbr_1483 1.2e-90 270.0 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales 201174|Actinobacteria U Drug resistance MFS transporter, drug H antiporter-2 family - - - - - - - - - - - - MFS_1 BHPHKHDA_01919 216816.GS08_08225 6.44e-49 155.0 COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4D17F@85004|Bifidobacteriales 201174|Actinobacteria J Binds the 23S rRNA rpmE GO:0008150,GO:0040007 - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 BHPHKHDA_01920 326426.Bbr_1481 5.78e-247 679.0 COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CYX4@85004|Bifidobacteriales 201174|Actinobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA GO:0008150,GO:0040007 - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 BHPHKHDA_01921 326426.Bbr_1480 2.39e-198 551.0 COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,4CZB3@85004|Bifidobacteriales 201174|Actinobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_25,Methyltransf_31 BHPHKHDA_01922 326426.Bbr_1479 5.37e-271 743.0 COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4CZYU@85004|Bifidobacteriales 201174|Actinobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 BHPHKHDA_01923 326426.Bbr_1478 1.08e-196 548.0 COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4CZQ6@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 BHPHKHDA_01924 326426.Bbr_1477 1.25e-240 663.0 COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CYTE@85004|Bifidobacteriales 201174|Actinobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 BHPHKHDA_01925 326426.Bbr_1476 2.73e-205 568.0 COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CZBX@85004|Bifidobacteriales 201174|Actinobacteria E Branched-chain amino acid ATP-binding cassette transporter livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C BHPHKHDA_01926 326426.Bbr_1475 4.8e-159 446.0 COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CZE0@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities livF - - ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C BHPHKHDA_01927 326426.Bbr_1474 2.92e-153 431.0 COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4CYVA@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the SUA5 family ywlC GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - Sua5_yciO_yrdC BHPHKHDA_01928 326426.Bbr_1473 9.69e-275 754.0 COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,4CZ4P@85004|Bifidobacteriales 201174|Actinobacteria M Glycosyl transferase family 4 rfe GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 BHPHKHDA_01929 326426.Bbr_1472 0.0 1009.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4CZ2S@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH BHPHKHDA_01930 326426.Bbr_1471 3.86e-156 437.0 COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CYZY@85004|Bifidobacteriales 201174|Actinobacteria L 3'-to-5' exoribonuclease specific for small oligoribonucleotides orn GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - ko:K13288 ko03008,map03008 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - RNase_T BHPHKHDA_01931 326426.Bbr_1470 0.0 921.0 COG0507@1|root,COG0507@2|Bacteria,2HFY1@201174|Actinobacteria,4CZ0C@85004|Bifidobacteriales 201174|Actinobacteria L PIF1-like helicase - - - - - - - - - - - - PIF1 BHPHKHDA_01932 216816.GS08_08180 0.0 888.0 COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2ISCW@201174|Actinobacteria,4D0HC@85004|Bifidobacteriales 201174|Actinobacteria S AMMECR1 - - - ko:K06990 - - - - ko00000,ko04812 - - - AMMECR1,Memo BHPHKHDA_01933 216816.GS08_08175 2.78e-254 701.0 COG1180@1|root,COG1180@2|Bacteria,2HZHC@201174|Actinobacteria,4D0G1@85004|Bifidobacteriales 201174|Actinobacteria O Radical SAM superfamily - - 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Radical_SAM BHPHKHDA_01934 326426.Bbr_1467 0.0 1201.0 COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4CZ6E@85004|Bifidobacteriales 201174|Actinobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit BHPHKHDA_01935 326426.Bbr_1466 2.29e-152 429.0 COG0629@1|root,COG0629@2|Bacteria,2GQIQ@201174|Actinobacteria,4D17E@85004|Bifidobacteriales 201174|Actinobacteria L Single-strand binding protein family ssb2 - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB BHPHKHDA_01936 326426.Bbr_1465 0.0 1460.0 COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,4CYVU@85004|Bifidobacteriales 201174|Actinobacteria O Peptidase family M13 pepO - 3.4.24.11,3.4.24.71 ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 - - - ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 - - - Peptidase_M13,Peptidase_M13_N BHPHKHDA_01937 326426.Bbr_1464 2.29e-196 546.0 COG3247@1|root,COG3247@2|Bacteria,2H3AT@201174|Actinobacteria,4D00R@85004|Bifidobacteriales 201174|Actinobacteria S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 BHPHKHDA_01938 326426.Bbr_1463 1.25e-192 533.0 COG0024@1|root,COG0024@2|Bacteria,2GKKB@201174|Actinobacteria,4CZAA@85004|Bifidobacteriales 201174|Actinobacteria E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 BHPHKHDA_01939 326426.Bbr_1462 6.38e-315 857.0 COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CZ2J@85004|Bifidobacteriales 201174|Actinobacteria C Citrate synthase, C-terminal domain gltA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt BHPHKHDA_01940 326426.Bbr_1461 7.18e-218 604.0 COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria,4CYVT@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA dapD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv1201c Hexapep_2,THDPS_M BHPHKHDA_01941 326426.Bbr_1460 0.0 2615.0 COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,2GISC@201174|Actinobacteria,4CZSD@85004|Bifidobacteriales 201174|Actinobacteria KL Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM BHPHKHDA_01942 326426.Bbr_1459 3.54e-128 364.0 COG0454@1|root,COG0456@2|Bacteria,2II91@201174|Actinobacteria,4D0SH@85004|Bifidobacteriales 201174|Actinobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 BHPHKHDA_01943 326426.Bbr_1458 1.24e-114 328.0 COG3727@1|root,COG3727@2|Bacteria,2IKPY@201174|Actinobacteria,4D0R6@85004|Bifidobacteriales 201174|Actinobacteria L May nick specific sequences that contain T G mispairs resulting from m5C-deamination vsr - - ko:K07458 - - - - ko00000,ko01000,ko03400 - - - Vsr BHPHKHDA_01944 326426.Bbr_1457 2.14e-257 705.0 COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4CYXG@85004|Bifidobacteriales 201174|Actinobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C BHPHKHDA_01945 326426.Bbr_1456 6.37e-299 814.0 COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CZQP@85004|Bifidobacteriales 201174|Actinobacteria E Aminotransferase class-V aspB - 2.6.1.1,2.6.1.2,2.6.1.66 ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 M00034 R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052,R07396 RC00006,RC00008,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 BHPHKHDA_01946 326426.Bbr_1455 2.39e-228 629.0 COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria,4CYW8@85004|Bifidobacteriales 201174|Actinobacteria FP Ppx/GppA phosphatase family ppx1 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA BHPHKHDA_01947 326426.Bbr_1454 1.21e-268 736.0 COG3568@1|root,COG3568@2|Bacteria,2I2GX@201174|Actinobacteria,4CYTX@85004|Bifidobacteriales 201174|Actinobacteria S Endonuclease/Exonuclease/phosphatase family - - - ko:K18353 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01504 - - - Exo_endo_phos BHPHKHDA_01949 326426.Bbr_1453 7.41e-102 294.0 COG3613@1|root,COG3613@2|Bacteria,2IHGG@201174|Actinobacteria,4D0T2@85004|Bifidobacteriales 201174|Actinobacteria F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr BHPHKHDA_01950 326426.Bbr_1452 1.35e-87 260.0 COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4D13A@85004|Bifidobacteriales 201174|Actinobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL BHPHKHDA_01951 326426.Bbr_1451 0.0 1225.0 COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4CYYC@85004|Bifidobacteriales 201174|Actinobacteria I AMP-binding enzyme fadD3 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding BHPHKHDA_01952 326426.Bbr_1450 3.71e-122 348.0 COG2249@1|root,COG2249@2|Bacteria,2HZE1@201174|Actinobacteria,4D11H@85004|Bifidobacteriales 201174|Actinobacteria S Flavodoxin-like fold ywrO - - - - - - - - - - - Flavodoxin_2 BHPHKHDA_01953 326426.Bbr_1449 1.02e-56 176.0 COG1722@1|root,COG1722@2|Bacteria,2GR0U@201174|Actinobacteria,4D18C@85004|Bifidobacteriales 201174|Actinobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S BHPHKHDA_01954 326426.Bbr_1448 0.0 883.0 COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CZU4@85004|Bifidobacteriales 201174|Actinobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 BHPHKHDA_01955 326426.Bbr_1447 0.0 1653.0 COG1328@1|root,COG1328@2|Bacteria,2GMGA@201174|Actinobacteria,4CYV3@85004|Bifidobacteriales 201174|Actinobacteria F Anaerobic ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD BHPHKHDA_01956 326426.Bbr_1446 2.3e-174 486.0 COG0602@1|root,COG0602@2|Bacteria,2H0HA@201174|Actinobacteria,4CYSC@85004|Bifidobacteriales 201174|Actinobacteria O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM BHPHKHDA_01957 326426.Bbr_1445 0.0 3252.0 COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2I1VH@201174|Actinobacteria,4CZ6Y@85004|Bifidobacteriales 201174|Actinobacteria I CoA enzyme activase uncharacterised domain (DUF2229) hgdC - - - - - - - - - - - BcrAD_BadFG,DUF2229,HGD-D BHPHKHDA_01958 326426.Bbr_1444 0.0 875.0 COG3572@1|root,COG3572@2|Bacteria,2GJPI@201174|Actinobacteria,4CYZP@85004|Bifidobacteriales 201174|Actinobacteria H Glutamate-cysteine ligase family 2(GCS2) egtA GO:0003674,GO:0003824,GO:0004357,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0044464,GO:0071944 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - iNJ661.Rv3704c GCS2 BHPHKHDA_01959 326426.Bbr_1443 5.49e-183 508.0 COG1309@1|root,COG1309@2|Bacteria,2I8DN@201174|Actinobacteria,4D2T6@85004|Bifidobacteriales 201174|Actinobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_6,TetR_N BHPHKHDA_01960 326426.Bbr_1442 0.0 1559.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4CZT6@85004|Bifidobacteriales 201174|Actinobacteria G Fibronectin type III-like domain bgl2 - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C BHPHKHDA_01962 326426.Bbr_1440 5.86e-61 187.0 COG1669@1|root,COG1669@2|Bacteria,2IMP4@201174|Actinobacteria,4D145@85004|Bifidobacteriales 201174|Actinobacteria S Nucleotidyltransferase domain - - - - - - - - - - - - NTP_transf_2 BHPHKHDA_01963 326426.Bbr_1439 1.26e-91 268.0 COG1669@1|root,COG1669@2|Bacteria,2IJSQ@201174|Actinobacteria,4D0XU@85004|Bifidobacteriales 201174|Actinobacteria S Nucleotidyltransferase substrate binding protein like - - - - - - - - - - - - NTase_sub_bind BHPHKHDA_01964 326426.Bbr_1438 3.88e-308 837.0 COG2730@1|root,COG2730@2|Bacteria,2I8WH@201174|Actinobacteria,4CZV7@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.4,3.2.1.58 ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 - R00308,R03115,R06200,R11307,R11308 RC00467 ko00000,ko00001,ko01000 - GH5,GH9 - Cellulase BHPHKHDA_01965 1437610.BREU_1897 1.31e-37 137.0 COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,2GKW1@201174|Actinobacteria,4D05P@85004|Bifidobacteriales 201174|Actinobacteria L PFAM Integrase catalytic - - - - - - - - - - - - HTH_21,rve,rve_2 BHPHKHDA_01966 702459.BBPR_1823 3.92e-22 90.5 COG2826@1|root,COG2826@2|Bacteria,2H4CW@201174|Actinobacteria,4D25Y@85004|Bifidobacteriales 201174|Actinobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_38 BHPHKHDA_01967 326426.Bbr_0472 0.0 877.0 2C04M@1|root,32Y5W@2|Bacteria,2IBPG@201174|Actinobacteria,4D07E@85004|Bifidobacteriales 201174|Actinobacteria S Psort location CytoplasmicMembrane, score 9.99 - - - - - - - - - - - - - BHPHKHDA_01969 216816.GS08_02275 1e-91 269.0 28PY9@1|root,2ZCI0@2|Bacteria,2INBV@201174|Actinobacteria,4D13Q@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01970 326426.Bbr_0474 9.44e-314 858.0 COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4CZKW@85004|Bifidobacteriales 201174|Actinobacteria DM Psort location CytoplasmicMembrane, score wcoI - - - - - - - - - - - AAA_31,CbiA,GNVR,ParA,Wzz BHPHKHDA_01971 216816.GS08_02285 1.59e-241 674.0 2DDMI@1|root,2ZIJN@2|Bacteria,2ICIR@201174|Actinobacteria,4D00F@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - FIVAR BHPHKHDA_01972 326426.Bbr_0476 1.21e-219 607.0 COG3583@1|root,COG3583@2|Bacteria,2I2GH@201174|Actinobacteria,4CYVC@85004|Bifidobacteriales 201174|Actinobacteria S G5 - - - ko:K21688 - - - - ko00000 - - - DUF348,G5,SLT BHPHKHDA_01973 216816.GS08_02300 1.59e-78 234.0 COG0526@1|root,COG0526@2|Bacteria,2IKP1@201174|Actinobacteria,4D11J@85004|Bifidobacteriales 201174|Actinobacteria O Belongs to the thioredoxin family trxA - 1.8.1.9 ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000,ko03110 - - - Thioredoxin BHPHKHDA_01974 216816.GS08_02305 1.83e-156 439.0 COG1051@1|root,COG1051@2|Bacteria,2GJGZ@201174|Actinobacteria,4CYT1@85004|Bifidobacteriales 201174|Actinobacteria F Domain of unknown function (DUF4916) - - - - - - - - - - - - DUF4916 BHPHKHDA_01975 326426.Bbr_0479 2e-204 565.0 COG2267@1|root,COG2267@2|Bacteria,2I2GI@201174|Actinobacteria,4CYXW@85004|Bifidobacteriales 201174|Actinobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 BHPHKHDA_01976 326426.Bbr_0480 2.94e-282 773.0 COG2816@1|root,COG2816@2|Bacteria,2GJZY@201174|Actinobacteria,4CZE5@85004|Bifidobacteriales 201174|Actinobacteria L NADH pyrophosphatase zinc ribbon domain nudC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase BHPHKHDA_01977 326426.Bbr_0481 3.63e-91 266.0 COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4D0W7@85004|Bifidobacteriales 201174|Actinobacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H BHPHKHDA_01978 326426.Bbr_0482 1.65e-283 775.0 COG4850@1|root,COG4850@2|Bacteria,2GKPS@201174|Actinobacteria,4CZ13@85004|Bifidobacteriales 201174|Actinobacteria S Uncharacterized conserved protein (DUF2183) - - - - - - - - - - - - DUF2183 BHPHKHDA_01979 326426.Bbr_0483 0.0 1870.0 COG1770@1|root,COG1770@2|Bacteria,2GNA9@201174|Actinobacteria,4CZ2X@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase, S9A B C family, catalytic domain protein ptrB - 3.4.21.83 ko:K01354 ko05142,ko05143,map05142,map05143 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S9,Peptidase_S9_N BHPHKHDA_01980 326426.Bbr_0484 2.09e-244 671.0 COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CZ08@85004|Bifidobacteriales 201174|Actinobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh BHPHKHDA_01981 326426.Bbr_0485 7.37e-272 744.0 COG0095@1|root,COG0095@2|Bacteria,2GJV5@201174|Actinobacteria,4CZYA@85004|Bifidobacteriales 201174|Actinobacteria H Biotin/lipoate A/B protein ligase family lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB BHPHKHDA_01982 326426.Bbr_0486 2.9e-167 468.0 COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,4CYYW@85004|Bifidobacteriales 201174|Actinobacteria K helix_turn_helix, cAMP Regulatory protein crp - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding BHPHKHDA_01983 326426.Bbr_0487 0.0 1426.0 COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,4CZAZ@85004|Bifidobacteriales 201174|Actinobacteria M Transglycosylase pon1 - - - - - - - - - - - PASTA,Transgly,Transpeptidase BHPHKHDA_01984 326426.Bbr_0488 8.2e-304 829.0 COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CZ9Z@85004|Bifidobacteriales 201174|Actinobacteria C NADH:flavin oxidoreductase / NADH oxidase family namA - - - - - - - - - - - Oxidored_FMN BHPHKHDA_01985 326426.Bbr_0489 2.17e-289 788.0 COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CYWW@85004|Bifidobacteriales 201174|Actinobacteria F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh BHPHKHDA_01986 326426.Bbr_0490 5.12e-158 445.0 COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria,4CZMT@85004|Bifidobacteriales 201174|Actinobacteria K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR BHPHKHDA_01987 326426.Bbr_0491 0.0 868.0 COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CYXZ@85004|Bifidobacteriales 201174|Actinobacteria C Galactose-1-phosphate uridyl transferase, N-terminal domain galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf BHPHKHDA_01988 326426.Bbr_0492 4.15e-297 811.0 COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,4CZNV@85004|Bifidobacteriales 201174|Actinobacteria G Belongs to the GHMP kinase family. GalK subfamily galK - 2.7.1.6,2.7.7.12 ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955,R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg BHPHKHDA_01989 1437608.BBIA_1789 1.26e-19 88.6 COG0477@1|root,COG2814@2|Bacteria,2GIZX@201174|Actinobacteria,4CZWX@85004|Bifidobacteriales 201174|Actinobacteria U Drug resistance MFS transporter, drug H antiporter-2 family - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - CBS,MFS_1 BHPHKHDA_01990 326426.Bbr_0493 7.93e-59 181.0 COG3830@1|root,COG3830@2|Bacteria,2IKS1@201174|Actinobacteria,4D11D@85004|Bifidobacteriales 201174|Actinobacteria T Belongs to the UPF0237 family - - - ko:K07166 - - - - ko00000 - - - ACT_6 BHPHKHDA_01991 326426.Bbr_0494 0.0 879.0 COG2848@1|root,COG2848@2|Bacteria,2HHMF@201174|Actinobacteria,4CZGB@85004|Bifidobacteriales 201174|Actinobacteria S UPF0210 protein - - - ko:K09157 - - - - ko00000 - - - DUF711 BHPHKHDA_01992 158787.BSCA_0673 3.37e-148 418.0 COG0219@1|root,COG0219@2|Bacteria,2IHN9@201174|Actinobacteria,4CZ0E@85004|Bifidobacteriales 201174|Actinobacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily spoU - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase BHPHKHDA_01993 326426.Bbr_0496 1.2e-236 650.0 COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CYRB@85004|Bifidobacteriales 201174|Actinobacteria L FES mutY GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD BHPHKHDA_01994 326426.Bbr_0497 1.05e-163 460.0 2E5CN@1|root,3304R@2|Bacteria,2I2GJ@201174|Actinobacteria,4D0SD@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - BHPHKHDA_01995 326426.Bbr_0498 0.0 2361.0 COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CZ3W@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB - 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 BHPHKHDA_01996 326426.Bbr_0499 0.0 2573.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales 201174|Actinobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 BHPHKHDA_01997 326426.Bbr_0500 0.0 1523.0 COG1305@1|root,COG1305@2|Bacteria,2HQBB@201174|Actinobacteria,4CZ3X@85004|Bifidobacteriales 201174|Actinobacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core BHPHKHDA_01998 326426.Bbr_0501 5.35e-307 837.0 COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4CZWT@85004|Bifidobacteriales 201174|Actinobacteria S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 BHPHKHDA_01999 326426.Bbr_0502 0.0 4130.0 COG0714@1|root,COG4733@1|root,COG0714@2|Bacteria,COG4733@2|Bacteria,2GMKC@201174|Actinobacteria,4CZFT@85004|Bifidobacteriales 201174|Actinobacteria S Fibronectin type 3 domain - - - - - - - - - - - - fn3 BHPHKHDA_02000 326426.Bbr_0504 5.07e-283 772.0 COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,4CZ9N@85004|Bifidobacteriales 201174|Actinobacteria KLT Protein tyrosine kinase pknK - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase BHPHKHDA_02001 326426.Bbr_0505 0.0 2628.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4CYQU@85004|Bifidobacteriales 201174|Actinobacteria L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C BHPHKHDA_02002 326426.Bbr_0506 0.0 2552.0 COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GM2E@201174|Actinobacteria,4CZ49@85004|Bifidobacteriales 201174|Actinobacteria L Belongs to the helicase family. UvrD subfamily uvrD2 - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C BHPHKHDA_02003 326426.Bbr_0507 1.51e-297 814.0 COG2271@1|root,COG2271@2|Bacteria,2I2GK@201174|Actinobacteria,4CZ0T@85004|Bifidobacteriales 201174|Actinobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 BHPHKHDA_02004 326426.Bbr_0508 9.28e-170 475.0 COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,4CZJ5@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB - 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N BHPHKHDA_02005 326426.Bbr_0509 2.56e-212 587.0 COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CZ34@85004|Bifidobacteriales 201174|Actinobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS BHPHKHDA_02006 216816.GS08_02580 0.0 1174.0 COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CZEJ@85004|Bifidobacteriales 201174|Actinobacteria J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnj - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2,RMMBL BHPHKHDA_02007 326426.Bbr_0511 0.0 1739.0 COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CZH4@85004|Bifidobacteriales 201174|Actinobacteria E Peptidase family M1 domain pepN - 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 BHPHKHDA_02008 326426.Bbr_0512 0.0 894.0 COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CYZX@85004|Bifidobacteriales 201174|Actinobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM GO:0008150,GO:0040007 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV BHPHKHDA_02009 326426.Bbr_0513 3.57e-157 440.0 COG0242@1|root,COG0242@2|Bacteria,2GNZ9@201174|Actinobacteria,4CZ7M@85004|Bifidobacteriales 201174|Actinobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase BHPHKHDA_02010 326426.Bbr_0514 0.0 920.0 COG0847@1|root,COG0847@2|Bacteria,2IC59@201174|Actinobacteria,4CZY1@85004|Bifidobacteriales 201174|Actinobacteria L Psort location Cytoplasmic, score - - - - - - - - - - - - - BHPHKHDA_02011 326426.Bbr_0515 8.44e-262 718.0 COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,4CZJX@85004|Bifidobacteriales 201174|Actinobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 BHPHKHDA_02012 326426.Bbr_0516 3.08e-267 734.0 COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,4CYYQ@85004|Bifidobacteriales 201174|Actinobacteria D Cell division ATP-binding protein FtsE ftsE GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran BHPHKHDA_02013 326426.Bbr_0517 1.9e-206 572.0 COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CZSQ@85004|Bifidobacteriales 201174|Actinobacteria D Part of the ABC transporter FtsEX involved in cellular division ftsX GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX BHPHKHDA_02014 326426.Bbr_0518 9.07e-206 582.0 COG3942@1|root,COG3942@2|Bacteria,2GZG8@201174|Actinobacteria,4CYQJ@85004|Bifidobacteriales 201174|Actinobacteria D CHAP domain protein - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP BHPHKHDA_02015 326426.Bbr_0519 1.33e-105 305.0 COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CZG4@85004|Bifidobacteriales 201174|Actinobacteria J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03664 - - - - ko00000 - - - SmpB BHPHKHDA_02016 326426.Bbr_0520 1.15e-196 548.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales 201174|Actinobacteria ET ABC transporter, substrate-binding protein, family 3 glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BHPHKHDA_02017 326426.Bbr_0521 6.49e-217 599.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria,4CZ6H@85004|Bifidobacteriales 201174|Actinobacteria ET ABC transporter, substrate-binding protein, family 3 glnH - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 BHPHKHDA_02018 326426.Bbr_0522 1.79e-221 612.0 COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,4CYSN@85004|Bifidobacteriales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component yecS - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 BHPHKHDA_02019 326426.Bbr_0523 3.69e-193 536.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CZSB@85004|Bifidobacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities tcyC - 3.6.3.21 ko:K02028,ko:K02029 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran BHPHKHDA_02020 326426.Bbr_0524 0.0 1241.0 COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4CZ1G@85004|Bifidobacteriales 201174|Actinobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iNJ661.Rv3436c GATase_6,SIS BHPHKHDA_02021 326426.Bbr_0525 4.88e-178 496.0 COG0564@1|root,COG0564@2|Bacteria,2GJ2Z@201174|Actinobacteria,4CZB2@85004|Bifidobacteriales 201174|Actinobacteria J RNA pseudouridylate synthase - - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 BHPHKHDA_02022 326426.Bbr_0526 2.38e-233 642.0 COG1609@1|root,COG1609@2|Bacteria,2GK1X@201174|Actinobacteria,4CZWK@85004|Bifidobacteriales 201174|Actinobacteria K Periplasmic binding protein domain - - - - - - - - - - - - LacI,Peripla_BP_3 ## 1876 queries scanned ## Total time (seconds): 1.8231618404388428 ## Rate: 1028.98 q/s