LOCUS       c00078_gnlPro..        14687 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FIBEKDEJ_89.
ACCESSION   c00078_gnlPro..
VERSION     c00078_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:58:35
            Original ID  :: gnl|Prokka|FIBEKDEJ_89
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14687
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..114)
                     /locus_tag="ctg78_1"
                     /transl_table=11
                     /translation="MNKIEVIQFFRHYKIFCVNAKYGIQYGFRIFYLIALQN"
     protocluster    1..14687
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1216:4687]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1217..4687
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14687
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14687
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             131..1078
                     /locus_tag="ctg78_2"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACRGKKQCAQCP
                     KAVDNAIIYASHLRGFHLPARKCEENIIIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(1217..1972)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-11, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 3.6e-25, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.3e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(2006..3952)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 201; E-value:
                     1.2e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-61, bitscore:
                     201.0, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-36, bitscore:
                     118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGYGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQDKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             complement(3989..4687)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_5"
                     /sec_met_domain="SucD_FumR (E-value: 8.9e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(4850..5752)
                     /locus_tag="ctg78_6"
                     /transl_table=11
                     /translation="MRLETCCNRQIDCMVCPQKSEGVLVYRHYPKGQHFSAEKCTQNCM
                     IFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEYIVYWFTELPLICEER
                     YKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCY
                     YPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVP
                     VYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRSA
                     NGEKISIICKEQGKDQEDE"
     CDS             5858..6460
                     /locus_tag="ctg78_7"
                     /transl_table=11
                     /translation="MKKAIFFVYFICLVVSGLSAQNWDINTLHRVNSWDGKFVRNYNKI
                     ISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYVGTSVAGAFVVTYGMKYLVDRERPY
                     DKYPDRVHAYSHEGSPSFPSGHTATAFALATSLSVKYPKWYVIAPSALWACSVGVSRMN
                     EGVHYPSDVLAGAAIGAGCAVVNIYVNKWLNKWLFGE"
     CDS             6457..6564
                     /locus_tag="ctg78_8"
                     /transl_table=11
                     /translation="MILGANYAEYAELDKLNPHNPRLSLFQVGYWIIVL"
     CDS             complement(6543..8159)
                     /locus_tag="ctg78_9"
                     /transl_table=11
                     /translation="MMKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVDKV
                     DEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVIQP
                     VSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVDDQ
                     LYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLILD
                     LQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVDEY
                     SASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRCIQ
                     KPYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRTVY
                     GGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFNEK
                     FEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMNST
                     NQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(8188..8646)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_10"
                     /sec_met_domain="CTP_transf_like (E-value: 5.5e-18,
                     bitscore: 58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             complement(8643..10577)
                     /locus_tag="ctg78_11"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRIAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             complement(10695..11831)
                     /locus_tag="ctg78_12"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             complement(11982..13016)
                     /locus_tag="ctg78_13"
                     /transl_table=11
                     /translation="MKVLYPVCIIFVLKIDIPMDILFLVGGLLLILLGANGLTDGAASV
                     AKRFHIPSIVIGLTIVAFGTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCT
                     ALFAPIAITRNTLKREIPLCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIF
                     LSYTFAIAKRDGSMKEPEKEHLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGAS
                     GIARGLGVSESIIGLTLVAGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLG
                     CSASITPLRLTGITNFDLWVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVL
                     IYNL"
ORIGIN
        1 attttgcaaa gctattaaat aaaaaatacg gaacccatac tgaatcccgt attttgcatt
       61 tacacaaaat attttatagt gcctaaaaaa ctgaattact tctattttat tcattccccg
      121 aaacttcttt atgaaagttt tcggggaatg tttcttttat gagtattatt tatctatttt
      181 tgtcactgca acaaacaaac aaatctactt gccgatgccc aactcttctg cttgcagagg
      241 taaaaaacaa tgcgctcaat gtcccaaggc tgtggacaat gcaataatat atgcttccca
      301 cctcagagga ttccatctgc cggcgcgaaa gtgtgaggaa aatattataa ttttcctgct
      361 gaaaggagaa gtgcttgtca acagtaagga gtatgcggga actgtgttgc atgcaggtga
      421 gttcatcctt caagctattg gttccaagta cgaaatactt gccatgacgg atgtggaatg
      481 cgtttgttac cggttcagta agcctgaatt cttctgtgag gaccggtata accatattat
      541 gaaagaggtt acccctccat tgatattcta tcctttgacc attactcccg agttgcagct
      601 ctttctggag agttccaagg cctatttgtc cgaggagaag atttgccggg aaatgctttg
      661 tttcaaacgg aaagaacttg ctttcattct tggaaattac tactccgact atgagctttc
      721 catgctgata catcctcttg cccagtatac taattccttc cactactttg tcttgcagaa
      781 tcatgccaaa gtcaagacgg tagaggaact tgcccagttg ggaggatata cagtagctac
      841 tttccggcgt atattcaatt ctgtttttca tcaaccggtg tacgagtgga tgatggaacg
      901 gaggaaggaa agcgtggttt atgaacttcg ttatacggat gcttctatat cagagatttg
      961 ctataaatat ggctttgaat cgctgcctca tttttccaat ttctgcaaaa agaatttcgg
     1021 ggcttctccc cgtagcttgc gtgccggcaa tttatctgaa gtaaacggca tgtcataaaa
     1081 aaactcctcc ggcggtttcc cggcagagga gtctcttgtg atattaatca aatatagtga
     1141 aagctgagtg ataaatctga gcttgctcaa aaggtttatc cgaagcgcat cctatattat
     1201 ttgcagaaag accggattag tctttcagtt tcgcaatgat aaagtcgcgg ttcaggcgag
     1261 caatgttgct gatggaaaca ttcttcgggc attcagcttc gcacgcacga gtgtttgtac
     1321 agttaccgaa accgagttcg tccatcttgc tcaacatagc cttggcacgg cgcaatgctt
     1381 ccggtttgcc ttggggcaac aggttcagct ggctcacctt ggcagaaacg aacagcatag
     1441 cagaaccgtt cttacaagca gccacacaag caccacaacc gatacagctg gcagcatcca
     1501 tagcctcgtc agcgatgggc ttcggaatca ggatagcgtt ggcatcctgg ggagcaccgg
     1561 tacgtacgct gacgtagccg cctgcctgca taatcttgtc gtaggccgta cggtcgacca
     1621 tcaagtcctt gataaccggg aaaccggcag agcgccacgg ttcaacagtg atggtatcgc
     1681 cgtcgttgaa acgacgcata taaatttggc aagtagtagc gccggttgca ggaccgtggg
     1741 ggtgtccgtt gatgtagagc gaacacatac cgcagatacc ttcgcggcag tcgtggtcga
     1801 atacaaccgg ttctttacct tcagaaatca gctgttcgtt caggatatcc agcatttcga
     1861 ggaatgaagt atcgcccggg atatctttca tttggtatgt ttcaaaagcg ccttttgctt
     1921 tcggaccctt ctggcgccat accttgagcg taaatgatat atttttatcc attttcttta
     1981 attctttaaa tgttcaactt cccgattagc tcttgtagtt acgagtctgt accttgattg
     2041 cttcgtaaac cagcggctct ttcagcaata ccggttcctt ttcgtcagaa ccctgatatt
     2101 cccagcaagc cacgtagaag tagttttcat cgtcacgctt ggcttcgcct tcttcagtct
     2161 gatattcttc acggaagtga ccaccgcagc tttcgttacg gttcagtgca tcgtaagcaa
     2221 ccagctcgcc catagtgatg aagtcgtaca gacggatagc cttgtcgagt tctacattca
     2281 taccttcctt gtcgcccggg atgaacagtt ctttctcgaa ctccttgcgg acttctttca
     2341 gcttcttcag accttccttc aagccttcag ccgtacgtcc catgcctaca tattcccaca
     2401 tgatgtggcc cagttccttg tggatagagt ctacagactt cttaccctta atattcatca
     2461 tccagtcaat cttgtcctga acagcctttt ctgcagctgc aaattcgggc aggtcggtag
     2521 agaaacgggg aactgtaatc tggtcggcca ggtaattctg gatagtgtaa ggcaatacga
     2581 agtaaccgtc ggccagacct tgcatcagcg cagaagcacc gaggcggttt gcaccgtggt
     2641 cggagaagtt acattcacca atagcgaaca gacccttgat ggaggtcatc agttcatagt
     2701 caacccagat accgcccatg gtatagtgga tagccggata aatcatcatc gggttttcgt
     2761 atgggctgac atcagtgatt tcttcataca tatcgaagag gttgccgtaa cgttgtgcaa
     2821 cgacatcttt acccagacgg ttgatagctt cggagaagtc aaggaatacg gcaaggccgg
     2881 tgttgttcac gccataaccc ttgtcgcagc gttctttggc tgcgcggctg gcaacgtcac
     2941 gcggaacgag gttaccgaat gccggataac ggcgttccag gtagtagtcg cggtcttcct
     3001 cgggaatatc ttttccttgc agtgtacctt cctgcagttt cttggcatct tccagcttct
     3061 tcggaaccca gatacgacca tcgttacgca gagattcgga catcaaagtc agcttagact
     3121 gcttgtcacc gtgaaccggg atacaagtgg ggtgaatctg tacgtaagca gggttggcaa
     3181 accaggcacc tttacggtag caagccattg ctgcagagca gttacatgcc attgcattgg
     3241 tagaaaggaa gtaggcattg ccgtaaccac cggtagcgat taccacagcg tgggcggcaa
     3301 aacgttccaa tttaccggta acgaggttct ttgcaatgat accgcgggca cgtccgtcaa
     3361 tgaggacaac gtcttccatt tcgtagcggg tatacagttt cacagtgcct acgttcacct
     3421 ggcggctcaa tgcagagtat gcacccagca acagctgttg tccggtctga cccttggcat
     3481 agaaagtacg ggatacctga gcaccaccga aagaacggtt gtccagtgta ccgccgtatt
     3541 cgcgggcgaa aggaacacct tgtgcaacgc attggtcgat aatattgttg gatacttcag
     3601 ccagacggta aacgttagct tcgcgggcac ggtagtcgcc accctttact gtatcgtaga
     3661 acagacggta tacagagtca ccgtcgtttt ggtaattctt agcagcattg ataccacctt
     3721 gtgcagcgat ggagtgtgca cggcgcggag agtcctggat gcagaagttg aatactctga
     3781 aacccatttc gcccagagag gcggcagcac tggcaccggc aagtccggtt cctactacga
     3841 tgatgtccag acgacgtttg ttggcagggt ttactaattt ttggtgagcc ttataattgg
     3901 tccatttctc agccaccggt ccttccggta ttttagaatc tatcttagtc ataatgcaat
     3961 ttacaattta gtcatttaca atttgaattt agcaagcgcc gcacaatgat tttgcaaaga
     4021 atacgacaac taccagagcg aagcagagga caacgatagt agaatagatg ttggagatac
     4081 atttccaacg gttaatccat actttgttgt tccagcccaa agactgcatg gagctccaga
     4141 aaccgtgagt gaggtggaac cacaatgcgc ccagccaaac gaggtaaagc actacgaata
     4201 ccggattgct gaaggtgttt tgaatgtgat agacaccgtt ggctgcatat gccagcgtga
     4261 gggtgtcggc atgcatgccc atgttgtgca tcaactcggg aagctgcatt ttagcccaga
     4321 agtttaccag gtgcaggccc aaacccacga ttacgatgat acccagtacg agcatgttct
     4381 gagaagccca ttccacagtc ttgggctttt ccgtaacggc atagcgttcg ctaccacgtg
     4441 ccttacggtt ctgcatagtc agccagaaag cgtagatgat gtggatgatg aataaggcag
     4501 ccagacctac cgtagccacc aatgcgtacc agtttgctcc caggaactca caaaccatgt
     4561 tgtagccatt agccgagact aatgcaacca ggttcatcgc catgtgaaat gtcagaaaca
     4621 ggacaagggc gataccggta acgctcatca ccactttcct tcctacagat gaattactta
     4681 accacataaa tgattgaatt taagttattt aatagtttga aaatttgttc tatcaggata
     4741 cttctgtaaa tgtttcgcaa aaataggaga aatccagcga taaagcaagc gattaaagaa
     4801 ataattccgt aatccggcag aatgcgaagt ttacggacaa gtaaaaggtt tactcgtcct
     4861 cctggtcttt gccttgctct ttgcagataa tggaaatctt ttctccgttt gccgaacgtt
     4921 ttctcagggc gcggggcgtg tctccgaaag agtctttgca gaagtgggca aagtgggata
     4981 gggaatcaaa gccatagcgg gcgctgatga ctgaaatgcg ttgtttggtg tattgcaggt
     5041 cgttcagaat tccttcacgt ttcttgtcca gaatccattc atagaccggg accccataca
     5101 tatttttaaa cagacggcgg aatgtggtgg tggtatatcc accgaggtgg gcaaactctt
     5161 ccacattctt caccttgtcg tagttctgca tgacgaaata ttggaagctt tccgtataag
     5221 tgctgatggg gtagaagaat gtactgattt ggtgtagcgg atagtagcat gtcaatatgt
     5281 ataccaattc ctggcatttc atttcaatgt atttgctgca cgcatagggt tgctcgttga
     5341 ggtagcaggc aaggcttttc aggagccctt cgagcatgga aatcgcggta agcggggtat
     5401 aagtcaaggg ggcttccgag cgtttcagta tctccttgta gcgctcttcg caaatcagag
     5461 gaagctcggt gaaccaatag acaatatatt ccacttcggt caaagccagg agttctactt
     5521 tggagccgat ggcttgcaag atgagctggc ggctttggag agtggtgccc ggatattcgt
     5581 cactgtttac aagtaattca cctttcagca taaatatcat gcagttctgt gtgcactttt
     5641 cagcagagaa atgttgtccc ttggggtagt ggcggtaaac caatactcct tctgattttt
     5701 ggggacatac catacaatca atctgtcggt tgcagcaagt ttccagtctc atgaaatgat
     5761 tagcgaatta ttataaatgt ggcaacaaag atagaatttt tttatgaaaa ctctatctat
     5821 ttgtcctatc tttgcgtcaa actaatataa aggacttatg aaaaaggcta ttttttttgt
     5881 atattttatc tgccttgttg tatccggtct ttcggcacag aattgggata ttaacacttt
     5941 gcatcgggtt aacagttggg atggcaagtt tgtccgtaac tataataaga taatttcacg
     6001 ttcggagccc tatgttgctg tcggtgttcc ggtggcgatg gcggttgccg cttggataaa
     6061 acatgataag ggtttgctga aagatgcggt ctacgtaggt acaagtgtag cgggggcttt
     6121 tgttgtgact tatggaatga aatatctggt ggaccgtgag cgtccttatg ataaatatcc
     6181 cgacagagtg catgcatata gccatgaagg cagcccgtct tttccttccg gacatacggc
     6241 gacggctttt gcccttgcca cctcgctcag tgtaaagtat cctaaatggt atgtgatagc
     6301 tccgtctgcc ctgtgggctt gttccgtggg agtttcccgt atgaacgagg gagtgcatta
     6361 tccgtcagat gtgttggcgg gggctgcaat cggtgctgga tgtgctgtgg tcaacatcta
     6421 cgtcaacaag tggctgaata agtggctgtt cggagaatga ttttaggcgc gaattacgcg
     6481 gaatacgcgg agttagataa actaaatccg cataatccgc gcctaagttt gtttcaagtc
     6541 ggctattgga taatagtgct gtagatgcct tcgttcagca cttttagagc ttgctgcacg
     6601 ctctggttcg tgctgttcat cacctggaag tattcgttca tgtcccatag gtcacgggct
     6661 atcaaggctt taagttgtgt cttgatgagc ggtagggatt ggttgtactg tttctcgtca
     6721 aacttgattt tctctttgtc ggcaagcgta cgtatttcgg caaggaagtt atcgtctatc
     6781 tcgaacttct cgttgaaggc ttcgaatttc ttgtatttgt tctgcaactc cttccggtgc
     6841 ttctcgatgt agccggtagt ggctttgata accacgcctt tggctacgag gttgcggtga
     6901 tagtctgtgt actgggtagt gtcgatgggg acgaagaagt cgggcatgat acctccacct
     6961 ccgtaaacgg tacgtcccat acgcttggtc tgtgctttca gggagtcggc aaaatggata
     7021 ctgtccgcat gaatcatttc tccatgattg aagcggtcta tcagttcctg gttatactta
     7081 tcctgactgt tctcgccggt taggcggccg tcgaggttgg cggtgctgtc gtaaggcttc
     7141 tggatacaac ggcccgaagg agtatagtag cgggcgatag tgaggcgaat catggaaccg
     7201 tccggcaggt cgataggacg ctgtactaat cccttgccga aggtgcggcg tcctactacc
     7261 acgcctctgt cccagtcctg gatggctccg gtcacgattt cactggcaga agcggagtac
     7321 tcgtccacca atatgatgag acggccgttc ttgaagttgc ccgtaccttt ggcaaagaaa
     7381 tcactgcggc gtgcggccct tccttcggtg tagacgatga gttctttttg cttcagaaat
     7441 tcgttggcaa ggtcgatggc ggcattcaga taccctcctc catttccttg caggtcgagg
     7501 atgaggtctt tcattccttt cttttgcagg cttttcaggg cttctgcaaa ctcttcggcg
     7561 gtggttgccc cgaagcggtt gatacggata tagccggttt tgggttgtat catgtaagat
     7621 gcgtccaggc tgaggatggg aattttgtca cgcttcacgg tgaagtacag ctggtcgtcc
     7681 acgccacggc gcacgatggt gagtttcact tccgagtctt tcggtccgcg caggcggctc
     7741 ataatatctt ccgtgctcat ttttactccg gcaatggcgc tgtcattgac ggctacgata
     7801 cggtcgccgg caaggatgcc caccttctcg gaaggtccgt tgctcacggg ttgtatcaca
     7861 agcagggtat cttctatcat ctgaaactgt acgccgatgc cctcgaaatt gccttgcaac
     7921 ggctcgttca tcttcttcac ttcttcggcg ttgttgtagg tggagtgcgg gtcgagttgt
     7981 gccagcatct tgatgatggc ttcttccacc agcttgtctt catccacctt gtccacataa
     8041 aggttggtga tggcaaactc tgccatttgc agtttgcgca gggcttcatt gttcggcttt
     8101 tgcgcttgtg ccgtcaccgc gcatatacat attataatag taaatagttt tttcatcatt
     8161 tccattttaa tccctaatcc tttatcctta atccctaatc tccattccct ccggtatgaa
     8221 catgcttatg tccttgccgt attgcagcag ttcgcgcacg gtggtggaac tgacgcaggt
     8281 aagttccggc tcggtgaaga gcaggatggt ttctatgccg gtcagtttgc ggttgatgtc
     8341 ggcaatggtt tcctcgtatt cgaaatcctt cacggtgcgt atgccgcgta ttatcagact
     8401 ggcatctacc tgccgggcaa agtcgatagt caggcagtca taggactgca caatgatgcg
     8461 cggctcgttc cggtagtagt ctcgtatcat ttgttcgcgc ttttccaagg ggaaatacgt
     8521 attcttattt tcattgatgc cgatgcctat gacgatttcg tctataaaag tcagtgcacg
     8581 gctcactacc gaagagtgtc cgatagtaaa cgggtcgaat gttcccggaa agatagctct
     8641 tctcatgatg ccaaatcttc ttctataacc aagttgttga taataaagtt ttgtcgttcc
     8701 atggtattct tacccatgta gaattccagc agctctttta cgaggtctgt cttgcgcagg
     8761 gacacttgtt ccagacgcat atccttgccg ataaaatgct tgaactcgtc gggcgagatt
     8821 tctcccagac ctttgaatcg ggtgatttcg gggttgggac ccagttcttc aatggctttc
     8881 acacgttcct cctctgtata gcaataactt gtcttctttt tgttgcgcac gcggaagaga
     8941 ggggtttgca ggatatatac atgccctttc tttatcaggt cggggaagaa ctgcaggaag
     9001 aaggtgatga tgagcaggcg gatgtgcatg ccgtccacat cggcatcggt agctacgatg
     9061 actttgttgt agcgcagtgt ctctatgccg tcttctatat tcaaggctgc ttgaagcaag
     9121 ttgaattctt cgttttcata aactactttc ttggtgagtc cgtaggaatt tagcggttta
     9181 ccacgcaggc tgaatactgc ttgggtattc acgtcgcggc tcttggtgat ggaaccgctg
     9241 gcggagtctc cctcggtaat gaagatgcag gattcggttt cctggtcttt gcctttaccg
     9301 tcactcaagt ggtagcggca gtcgcgcagc ttgcggttgt gcaggttggc tttcttggcg
     9361 cgttcgcgtg ccagcttggt gacgccggca atggctttgc gctctttctc ggagtcttgt
     9421 atcttttgca gcatcacttc ggccacaagc gggttcttgt ggaggtagtt gtccacttcc
     9481 gtcttgatga agtctcctac gtatttgttc accgtggggc cggcgggctt gtgttcctgc
     9541 ggcgcggcag gccacatgtt gttgctgccc agtttcgttt tggtctggct ctcgaacatg
     9601 ggttcctcca cgtcgatggc aatggcggct accagtccgt tgcggatgtc ggcatattcc
     9661 tggttcttgt tgtagaactc cttgatggta cgggcaatgt gttccttcaa ggcagtctgg
     9721 tgtgtgccgc cttgggtggt gtgttgcccg ttgacaaagg agtagtactc ttcgccgtat
     9781 tggttggtgt gtgtgaaggc aatctcgatg tcctctcctt tcaggtggat gatgtcgtaa
     9841 aggccttcgc tggtcatgtt gtctttcagc aagtcctcca gcccgtggcg ggaaacgatg
     9901 cgctggccgt tgtaaatgaa ggtgaggccc gtattcaggt aggtgtagtt gcgcagcagg
     9961 gtttctacga actggttctg gaaggaatag ttcaagaaga gtgtggcgtc cggttcgaag
    10021 aagatatagg ttccgctttc ttctgtcgag tcttcggtca catcactcaa cagcgttcct
    10081 ttttcaaaga tggcgatacg taccttgccg tcgcggtagc tgcgtacttc gaagcggctg
    10141 ctcagcgcat tgactgcctt gatacctacg ccgttcagtc cgacactttt cttgaaagcc
    10201 ttcgagtcat atttaccccc ggtattcagt ttgctgaccg cctctaccag tttgccttgc
    10261 ggaatgcctc gtccatagtc gcgtacgctg acacgcagac tgtcttctat agtcacttct
    10321 atacgctttc cggcacccat cttgaactcg tcgatgctgt tgtccatcac ttctttcagc
    10381 aacacataga tgccgtcatc gttctgtgag ccgtcgccca gacggcctat gtacataccg
    10441 gaacggacac ggatatgctc catgtcgtcc aggtggcgga tgttgtcgtc ggtatattcc
    10501 acgctggaaa cggggctctc tgtgatattg ttgtctgctt cttccagcgg cagggtcata
    10561 ttgttgttat cttccataag tacgttattc cttcatattg cgcattgcga caaaggtaat
    10621 gagaaattcg ggggttcgca aaaaaataat gtcttttatg gacttctgac aagcttatat
    10681 tctggattta gaacttattt tattcctttc acaaagcatc ttctccgttt atgctgttcc
    10741 gtcttgaagt actcccactg cgcttgcacc ttgccgttca gctccagctc cggattactc
    10801 tcggcatact cgaaaccaag ttgctgatag acggggataa ggtcggagaa caacaatgca
    10861 tttaccccct tgttctgata ctccggtttc acggcaacca gcagcaaatc gagcatcttg
    10921 ggatatttct tcaagaagat ggtcttggcc aggtgatacc aacccatagg aagcaggcgc
    10981 ccgtgggctt tttgcaacgc ttcggcgagt gacggcatgg aaatgcctac ggcaagcagc
    11041 tggtcatcgg catcggtaat caatgtcacc atgcgtaggt cgaggatggg caggtacatc
    11101 ttgacgtatt ggtcaatctg ccgttggctc agtgcagaat agccatagag tggctgatag
    11161 gcttcgttca tcagttcgaa gatggcctga ccgtagtctt gggcaatctt cttggcagat
    11221 gtgtatttct ttaccttgag gttatacttg cgctggatga ggtcggagat gcgcttgtgc
    11281 ttgtcgggta tggcgtcggg aatgtagatt ttgtactcca cccaatcggc atccttctca
    11341 aagcccatgc gttccagatg ttgcggatag tagggatagt tataaatggt ggccatggtg
    11401 ctgagctggt cgaatccttc gatgagcata ccttcggcat cgaaatctgt gaatcccagc
    11461 gggccttgta tatgtgtcat tccccgttct tttccccatt cttccacggt gcgaatcagg
    11521 gcatcggaga cttccgcatc atcgatgaag tctatccagc cgaagcggac ttcctttttg
    11581 ttccaggttt ggtttgcctt gtggttgatg atggcagcta cacgtcctac gattttacct
    11641 tcccgataag ccaggaaata gtcggcttca caaaattcga atgcagcgtt tttcttcttg
    11701 ttgaaggtgt tgagcatgtc atcgaaaagg tcggggacgg aataagggtt gtttttgtat
    11761 agcaggtagt tgaaacggat aaagcgctcc agttcccgtc ttgtggttac tttcttgatt
    11821 gtaattgcca tagttgttca atattgagac cacaaaggta atgcaaactg agagcagaac
    11881 aaaataagct tgcttatttt ttatgccgag gtacagcttg ccttatttaa aaatacgtga
    11941 taatctttaa aataccgcgt agggtgtttg taaatttgct gttagaggtt gtatatcagt
    12001 accgctgtgt aggcaatgta gcagagaatc agaatgcttc cttccacccg ggtgatgatg
    12061 cgtttcccga aaaagatacc gaacagccaa agcaggatgc tggaccctac gagtacccac
    12121 aaatcgaaat tggtgatgcc cgtcagacgc agtggagtga tggaggccga acaacccagt
    12181 acgaagaata tattgaagag attacttccg atgacgtttc cgatggctat ttcggggttt
    12241 ttcttcaagg cggctacgat ggaggtggcg agttcgggta atgaagtgcc gcctgctacg
    12301 agcgtgagac cgatgatgga ttcgctgaca cccaatccgc gggctatgcc gctggcaccg
    12361 tctacaaaga aattacctcc gatgatgagg ccggcaagtc cgccgagaat gtatagggcg
    12421 gatttccacg cgggtaacag cctgatttcg tcttcttcct gtaagtgctc cttttccggt
    12481 tccttcatac ttccatccct ttttgcaatg gcaaaagtat aactcagaaa aatggtaaag
    12541 aagcatagca gcaataggcc gtcggtgatg ctgagtatgt tctccccact gctgtccagt
    12601 aagacgtcgt tggcacaaat cagcagggcg aaggatgaaa ggatgcaaag gggtatttcg
    12661 cgtttcagtg tgttacgggt aatggctatc ggggcaaaaa gggccgtaca acccacaatc
    12721 atcagggtat tgaacgtatt gcttcccacc acattgccga tggcaatgtc tgcactgcct
    12781 tttagggcag aggatatgct gacggtgagt tccggtgcgg aagtaccgaa ggcgacaatg
    12841 gtaagcccga tgacgatgga cggtatatgg aaacgtttgg caacggatgc ggcaccgtct
    12901 gtcaagccat tggcacccag aagaatgagg agcagtcctc cgacaagaaa caatatatcc
    12961 ataggtatgt caattttgag tacaaagata atgcaaaccg gatacagaac tttcatgttt
    13021 gcatgaaaaa gttatgttga ttaggatagg aagttaaaaa cattccgtat gtttgaagca
    13081 tttattgggt atatttgcat aattaaagaa tcaaatcaag aagtttatat atgaaggtta
    13141 tccgtgcttt ctgtctttgt tggctgttga tgctggcaga cggagtgtca gctcagttgg
    13201 tagataaagt gctcagtgtt ttaggtgagg atagtgtggg gagtgtcaca gtggcaagga
    13261 ctgactccga ttcgattcag ttgtcgcttg tccggcagga gttggaaaca gcccggctga
    13321 atgaggcgaa cctgcggatg gaaatggagc agatgaagtt ggcgggctat gcggccgatt
    13381 cggtgaagct ggcattgcag aaacaacgca ttgattcgtt gcggacggtg acaccgggta
    13441 ttccggtggt ggtggagaag gacactttgt tctatctgta tgccaagcgt ggagggcata
    13501 cgccccaaca gcgagccaaa gatgtaagca acgtcatcga agcattgggc acgcgtttca
    13561 atctgcgtcc ggactctgtt tatttagaga gtacggatat tgttacagac ttgatgtatg
    13621 gcgaaaaggt catcatttcc tttaccgatc aggatgcttt gtgggaaaac tgtacccgcg
    13681 accagctggc cgccagcaag aggcatgtcg tggtggacaa actgaaagcc atgcagaagg
    13741 agcatagctt gtggcagttg ggtaagcgta tcttgtactt tatcctggtg cttgtgggac
    13801 agttcttctt gttcaagttt accaactggc tgttcagaaa actcaaacta cgcattcaga
    13861 agctgaagga taccaagctg aaaccgatct ctattcagga ttatgaattg ctggatacgc
    13921 agaagcaggt caacctgctg gtgtttgttg ccaacctggt gcgttatgta gtcatgctgt
    13981 tgcagttgct gctgacggtt ccgttattat tctccatttt ccctcagacc aagagcttgg
    14041 cttatacatt attctcctac atctggaatc ctataaaggt catcttgaat ggaatagccg
    14101 actatatacc caatctgttc actatctttg tgatatgcta tgcggtgaag tatctggtca
    14161 gactggtgcg ttatcttgcc aatgaggtgc aggctgaacg gctgaagata aacggcttct
    14221 atccggattg ggccattcct acctatcata ttgtgcgctt cttgctttat gcgtttatga
    14281 ttgccatgat ttacccttat ctgccgggtt ccaagtcggg agtcttccag ggaatctccg
    14341 tgtttgtcgg cttgattgtt tcgctcggtt ccagtacggt tatcggcaat atcattgcag
    14401 gactggtcat aacctacatg cggcctttca agctgggtga ccgcatcaag ctgaacgata
    14461 ctacgggcaa catcattgag aaaacaccgc tcgtcacccg catccgtact ccgaagaatg
    14521 aggtggtgac cattccgaac tctttcatca tgtcttccca tacggtcaat tacagccagt
    14581 ctgcccgtga gtatggattg attatccatt cggaggtcag tattggctac gatgttccgt
    14641 ggcggaagac acatcagctg ttgatagagg ctgcattgaa tactcct
//
