LOCUS       c00071_gnlPro..        16405 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IILMLJAJ_158.
ACCESSION   c00071_gnlPro..
VERSION     c00071_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 07:59:35
            Original ID  :: gnl|Prokka|IILMLJAJ_158
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16405
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16405
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2979:6537](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2980..6537
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16405
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16405
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(407..1561)
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1741..2946
                     /locus_tag="ctg71_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             2980..6537
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6662..6850
                     /locus_tag="ctg71_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6861..7721)
                     /locus_tag="ctg71_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7749..8579)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg71_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8576..9802)
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10275..11561
                     /locus_tag="ctg71_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11524..11856)
                     /locus_tag="ctg71_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(11884..14637)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPHFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAIRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(14970..16196)
                     /locus_tag="ctg71_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 cttttattca ttttagttga tacttatagt agtcaaccaa atccagggta agacataacc
       61 gcatgttcca atcacattga acgcatcagc tacttcaata gtactgctct ctctgaaaac
      121 attaaatcat atatcagtca ataatacata aattatcagt ccttaatact tgatttctca
      181 attattaata tctgagaaat caaacgttaa cagttgagat atcagatatt aacatcctgt
      241 aaatcaaaga ataacacagt aaaaacggta tttatcagga cgatgcagag tgagagcaag
      301 tccttgctct cactctgcta ccactggatc tctaacagct aaaacatcga tgaataaagg
      361 gatacagacg aactgttaga gcatgagagc aaaagcacta tctttttcac tgggggagag
      421 taagcaaaag aaacgcacga taccggcttt gaggcgtcac cggtactaac ggcaaatatc
      481 cggcacacac ccgattattc tctacggaca aagggaacga agccgacatc tgccgatgtt
      541 cctccaaagc ctgaccggct aaaggataat aatcaatccg aaaaactcct tccgcatccg
      601 cagccaaata acgatccgtc aagagccatg ccaccacccc catattcatt cgcagattaa
      661 tttcgacaca aggatgaatc cggtaaacag gcgcttcatc cggaaaatga caaatcatca
      721 tatccactcc caagtatcca tgataaaagc caccgaacaa agctgacaat tcttcttcca
      781 aacgagtccg cagcctgata aattcttctt gtggcacata agccgatagt ttctgcagaa
      841 tcttctcgtc agacagcaag tcattccctg catacatccc actcccaccc gtgtggaaga
      901 ccgaatatcc ggcaaaaaca acccttcctc tcccgtcagc ataaaactcc atagcgaaat
      961 cttccacctt attatatata ggttcgccta ccaccccacc ctgagaagca gcgacacggg
     1021 cacaccaacc ggaaataaaa gtagtaaata tgcctttaca ccaattcaat cctttcccgc
     1081 ttccggaaag cggagctttt aacaagcacg cttcccgccc ttcgacgaac gcactgcact
     1141 ccgccaaagt actcaaataa aaagattctc cacagaagta ttcattcaac cgcaacccag
     1201 gcaacaactt taccgcctgc agacgatgcg aatgctctct cagaatattc atataatccg
     1261 cagaaggcag ctccgtctga tctgccccca atgtcatcaa acgcttccgc aaagcagggt
     1321 cccaccccca cggagagaac ttccggtctt taccgtcagc cacttccggt tccgtcaaca
     1381 aggccacatc catgcccaaa agttcactct ttgttttcag gaagtccgca ttataagcag
     1441 acggtgcaag caccgcactt cccgcttcgg cataccacat aggaagcaac gccaggtcac
     1501 tcgccatctg tcgggcggaa gccggcgcca tatagttcgt ctcaccgctt gccaacgcca
     1561 tatcatgctc cggattgaat atataaacag gtcttttcgt catgtcaaag atggattcaa
     1621 cacattattc tgcaaatata tacaggaaat aatcaggaac ttacacaata aagagaaact
     1681 tataaattaa agcacatttt tgctatctct actttgcaaa tcctaaaaaa agcactatat
     1741 ttgccagccg aaaaacaaag aaacgaaatg gaatcattct atcgcacaca cgcctacctc
     1801 gttgagcaca ccaatgcccc cgttcgccgc gatcttatgg acgagatcga ctggagtgac
     1861 cgtctgattg gtatcaaagg gacacgtggc gtaggaaaaa ccactttcct cctgcagtac
     1921 gccaaagaga aattcggcac cgaccgttcc tgtctgttca tcaatatgaa caacttttat
     1981 ttctccggtc acagccttgt tgacttcgcc aacgagtttc agaaacgtgg cggaaaagta
     2041 ctgctgatcg accaggtgtt caaacatccc gaatggagca aagagctacg aatgtgctat
     2101 gaccgtttcc ccagcctgaa gattgtcttc accggttctt ccgtcatgcg actcaaagag
     2161 gaaaacctcg aattgcgtga cattgcgaaa agttataacc tgcgcggatt ctctttccgt
     2221 gaatttctga acctgcagac aggaatgaaa ttccgggcat acagcctcga agaaatcctc
     2281 agtacacatg aacagatagc caaaggagta ctttccaaag tacgaccgct ggattatttt
     2341 caggattacc tgcatcatgg tttctaccct ttcttccttg aaaaacgtaa tttctcggag
     2401 aatctgctga aaacaatgaa catgatggta gaagtggata tcttgctgat caaacaaatt
     2461 gagctgaaat atctttcaaa gataaaaaaa ttactatatt tgttggctgt ggacggaccg
     2521 aaagctccga acgtgagcca actggcaagt gacgtacaga catcccgcgc tacggtaatg
     2581 aactatatca agtatctggc agacgcgcgt ctgattaatc tggtttaccc gaaaggagaa
     2641 gaattcccaa agaaaccgtc aaagattatg atgcacaact ctaacctgat gtactccatt
     2701 tatccggtga aagtggaaga acaggatgta ctcgacacgt tcttcgttaa cactttatgg
     2761 aaagaccata aggtacataa aggagataaa aacgtctctt tcatggtaga cgaagtgatg
     2821 ccgttcaaaa tttgtgcgga aggtacaaaa ataaagaata acccggacgt gacgtatgcg
     2881 ttgcaaaagg ctgagatagg ccgcggcaac caaatacctc tttggatgtt cggattctta
     2941 tactaaaaag atttatttac ttaaatattt aatttagtta tgactaaaca gaagaaattc
     3001 atcacatgtg atggtaacca agctgcagca catatctcgt atatgttctc tgaagtagca
     3061 gctatctacc ccatcactcc ttcttcgact atggctgagt acgtagacga atgggctgcc
     3121 gcaggacgta agaacatctt cggcgaaaca gtattggtac aggaaatgca atctgaaggt
     3181 ggtgctgccg gtgcagttca cggttctctt caggctggtg cattgactac tacttacact
     3241 gcttctcagg gtcttctttt gatgatccct aacatgtaca agattgccgg tgaattcttg
     3301 ccttgtgtat tccacgtttc tgctcgtaca ctggcttctc acgcattgtg tatcttcggt
     3361 gaccatcagg acgtaatgtc agctcgtcaa accggcttcg ctatgttggc agaaggttct
     3421 gtacaggaag ttatggattt ggcaggtgtt gctcatctgg ctactatcaa atcacgcgtt
     3481 ccgttcatga acttcttcga tggtttccgt acttctcacg aaatccagaa gatcgaaatg
     3541 ttggaaaacg acgacctcgc tccgctgatc gaccaggaag ctttggctga attccgtgcc
     3601 cgtgcactga atccgatgaa gccggttgcc cgtggtatgg ctgaaaaccc cgaccacttc
     3661 ttccaacatc gtgaatcatg caataactac tatgaagcag ttcctgctat cgtagaagaa
     3721 tacatgaacg aaatttccaa gatcacaggc cgcaaatacg gtttgttcga ttactacggt
     3781 gcagaagatg cagaacgcgt aattatcgca atgggttctg taactgaagc tgcccgcgaa
     3841 gctatcgacc acttggtagc aaacggcgaa aaagtaggta tggttgccgt acacttgtat
     3901 cgtccgttct ctgctaaaca cttcctggct gctgtaccca agactgcaaa gagcatcgca
     3961 gtgcttgacc gtacaaaaga accgggtgct aacggcgaac ctctttacct tgacgttaaa
     4021 gactgcttct atggcgcaga aaatgctcct gttatcgttg gcggtcgcta cggtctgggt
     4081 tcaaaagata caactccggc acagatcatc tctgtattcg aaaacttggc tatgccaatg
     4141 ccgaagaacc acttcactat cggtatcgta gacgacgtta cgttcacttc tcttcctcag
     4201 aaagaagaaa tcgctctggg cggtgaaggt atgttcgaag ctaaattcta cggtctgggt
     4261 gctgacggta ctgtaggtgc caacaagaac tctgttaaga ttatcggtga caacaccgac
     4321 aaacactgtc aggcttactt ctcttacgac tccaagaagt cgggtggttt cacttgttct
     4381 cacttgcgtt tcggtgatac tccgatccgt tctacttact tggtaaatac tccgaacttc
     4441 gttgcttgtc acgttcaggc ttacctgcac atgtacgacg taacacgtgg tttgcgtaag
     4501 aacggttctt tcttgctgaa taccatctgg gaaggcgaag aactggctaa gaacctgcct
     4561 aacaaggtga agaaatactt tgcacagaac aacatctctg tatactatat caacgcaact
     4621 cagattgcaa tggaaattgg tttgggcaac cgtaccaata caatccttca gtctgcattc
     4681 ttccgtatca caggcgtaat ccctgtagat caagctgttg aacagatgaa gaaattcatc
     4741 gttaagtctt acggcaagaa gggtgaagac gttgttaaca agaactacgc tgctgtagac
     4801 cgcggtggtg aatacaagac tctgactgtc gatcctgctt gggctaacct gccggatgat
     4861 gcaaaagcag aaaacaatga tcctgctttc atcaacgaag tagttcgtcc gatcaatgca
     4921 caggacggtg acttgctgcc ggtatctgca ttcaagggta tcgaagacgg tacttggtat
     4981 caaggtactt ccaaatacga aaaacgtggt gtagctgcat tcgttcccga atggaatgct
     5041 gaaaactgta ttcagtgtaa caagtgtgct tacgtttgtc ctcacgcttc tatccgtccg
     5101 ttcgtactcg atgctgaaga gcagaagggt gctaagttcg agcaactgaa agctgtaggt
     5161 aaagcattcg atggtatgac attccgtatt caggtagacg ttctcgattg tctgggttgc
     5221 ggtaactgtg ccgacatctg tccgggtaat ccgaagaagg gtggcaaggc attgaccatg
     5281 aaacaccttg aaagccagtt ggccgaagct gataactgga cttactgcgc tgaaaacgtg
     5341 aagagcaaac aacacctggt agacatcaag gctaacgtga agaactctca gttcgcaact
     5401 ccgttgtttg agttctcagg cgcttgctcc ggttgtggtg aaactccgta cgtgaaactg
     5461 atttctcagt tgttcggtga ccgtgaaatg gttgctaacg ctacaggatg ttcttctatc
     5521 tactccggtt cagttccttc tactccgtac actatgaacg aaaagggtca cggtcctgca
     5581 tgggctaact ccttgttcga agacttctgt gaatttggtc tgggtatgga actggctaac
     5641 gaaaagatgc gtgcccgtct ggtgaaagta atgaacgaag ctatcgcttc tgattgctgc
     5701 ccggctgaat acaaagaagt atttgctgaa tggatcaaca atatgctgga tgcagaaaag
     5761 actaaggaac tggccgaaaa gatcattccg atggtagaag ctgctaaaga taaatgcaac
     5821 cactgcaagc aaatcgctga tctgcaacaa tatcttgtta aacgcagcca atggatcatc
     5881 ggtggtgacg gtgcttctta tgatatcggt tacggtggtc ttgaccatgt aatcgcttcc
     5941 ggtaaggacg ttaacatcct tgtattggat actgaggttt actctaacac aggtggtcag
     6001 tcttctaaag ctactccggt aggcgctatc gctaagtttg ctgctgcagg taagcgtgta
     6061 cgtaagaaag acctcggtct gatggctact acttacggtt atgtatatgt tgctcagatt
     6121 gcaatgggtg ctgaccaggc tcagactctg aaagctatcc gtgaagctga agcatatccg
     6181 ggaccatcac tgatcatcgc ttacgctcca tgtatcaacc acggtctgaa agccggtatg
     6241 ggtaagagcc aggaagaaga agaaaaggct gttaagtgcg gttactggca cttgtggcgt
     6301 tacaaccctg ctttggaaga agaaggcaag aatccgttcc aactggatag caaagaacct
     6361 aactgggaag acttccaagg tttcttgaag ggtgaagttc gttacgcttc tgtaatgaaa
     6421 caatatcctg ctgaagctga agaactgttt aaagctgctg aagaaaacgc taaatggcgt
     6481 tacaacagct acaaacgtct tgccagagaa aactggggag ctgatacagc tgaataataa
     6541 gtagaaatac tttgtacata ataaaaggca ggaatcctgg aaacagattc ctgccttttt
     6601 tgtttatatc ttagaagtaa cgattacttc tcacgaagat attcattaaa actctaaaga
     6661 tatgatcgga tttgttattt ggattatcgg tttgatactg actttcagag ctgccataga
     6721 gatttggaat ataaatgcgg ctgtagagaa aagacttata gcgattgtat taatcgttct
     6781 taccagctgg ctgggactac ttttctacta cttctatggt aaagaaagaa tggcgggatg
     6841 gttgaagtag tgtttgcata tcaatctttc tcaggaatcc aactgttcac cagttcctga
     6901 tgttcttcca tccattgacg ggcagcctgt ctttccgttg tctgcgcctc ttccagagca
     6961 gtcattaagg agctgatttc cgcatctgtc agacgaatgt tgcccaaaag ttcggcagca
     7021 aaagggtctt tctcgctaaa acctttccat gctatggtat gaatggattc cgtatttcca
     7081 tatatcagct tcgggtcctg aagaactttc agcttgaaac ggtcgaacat ccagtgaggc
     7141 gtccatcccg tcacgacaat ccagtctttc ttatcaatcg ctttctttag ggaagcagtc
     7201 atggcaggtc cgctcgaagt catcagttta taatccaatc catagtcttt gatggcctga
     7261 tcggtagctt tcataatacc ggctccggca tcaataccga caatctgacc ggagaaacgt
     7321 tccttttccg cgttcagttc ttcgattgag ttgatcgtaa cgtaatccgg aaccaccagc
     7381 ccgatacggg caccatcata aatatccccg ataacttcga gtttatcccc gtattgtttc
     7441 atataatctt ccatagtgac aggcatccag acatccataa atacgtctgc tttcttacgg
     7501 gagatagagg taaatatagg tgcaaggtcg gcattcagca actttacatc gtacccctga
     7561 tcttcaaaaa tcgctttggc aaggtttgtc attgcaatac cttccgacca gttggcataa
     7621 gcgatactta tcttcttact ctttccgttg tctccgcagg aaacgaaggt taagagtatg
     7681 ccggcaataa acattgccgc aatcattttt atcttattca ttgattattc ctttctttgg
     7741 tgtgattctt atttcttttt actttttctg ttatctgcca taccctgagt gatgcggtcc
     7801 agcacgatcg ccaatatcac gactgcgata ccgccttcaa atccgagtcc gattttcatt
     7861 tgggtgatac ctttcagcac gatttctccc aatcctccgg cagaaatcat ggcagcaatc
     7921 actaccatcg aaagtgacat catgatcgtc tggttgattc ccgtcagaat agtaggcaac
     7981 gccaaaggca attgcacctt ataaagaagc tgccagggag tagctccaaa agagcgggag
     8041 gcttctacta cgtttttagg aacctgacga atgcccagac cggtcagacg aaccacagga
     8101 ggcattgcaa agatgatggt ggcaaaagct cccggcacag ttcccaatcc gaagaataga
     8161 acggcaggaa tcagatagac aaaggcaggc attgtctgca taaagtcgag gacagggcgc
     8221 attatcttgt tacaacgatc actgttggca gtccagattc ccaacggaac gcctaaaagc
     8281 aatgccagac aagtggaaga aagtaccaat gccaatgtct gcatcgtttc ttcccaaaag
     8341 cccatgccgt aaataagcaa taaacccaag agggtaaata cggctgtccc cttacccgac
     8401 ttaaaccagg cgagcgcagc cagcactgca attgtgatat aaaaaggtat tccaaacagt
     8461 acgtgctgaa aaccgtctat gaatcctccg atccccatgc tgagagcatc aaaaaaggaa
     8521 gcaaaatgtt ctgtgagcca attaatggca gtctctatat attgtccgat atttatcata
     8581 attctattgc gttttgaatg atttcattaa tttcttcttt atcttttccc gttacttcga
     8641 tgatcaatga ggaaagtggc actacgcctt caaactcccg attctcattt acgacccaga
     8701 ttggcgagtt cgtttttgtc atcaacggaa gaatatcttc cagcaccgta tcacccagca
     8761 ctgaatgaac ttcatgcctt actacggact cgatggagcg gatttgctct tttcgtagtt
     8821 tcagcaagtc attcaaccgc acctctccta ctaacagatt attggaatcg actaccggaa
     8881 gaacggtcag attccgttcg cgcatcttac ggatcagcac ctccgggcct tctttcttca
     8941 aacgtgccac tatgggttta tctaccataa cagaggaagc tgttataatc ttgcttcgat
     9001 ctacattctc cacaaatcgt tctacataag cgttggcagg ttcggtcagg atttcttccg
     9061 atgtaccgat ttgtacaatt tctccatcct tcatgatagc aatccggtca cccaatttaa
     9121 tcgcttcact caggtcgtga gtaataaaga caatcgtttt tttcatcttc gactgcaaag
     9181 tcagcagttc atcctgcatc tgcacacgga tcaaaggatc gagtgccgag aaggcctcat
     9241 ccatcaacag gacttcggga ttattggcca aagcccgcgc cagcccgaca cgctgctgca
     9301 tcccacccga cagttcactt accatctgat tctcgtagcc tttcagcccc accagttgca
     9361 tactttccat cgctttctgc tcccgttctc ccttttttac tccctgtagt tcgagcccga
     9421 aagctatatt atgcaagaca gaacggtgag gaagcagacc gaagttctga aagaccatag
     9481 ccagttcttt ccggcgaatc tgcaacagtt ccttatccga cactttggct atgtctgttc
     9541 cattgataat cacttctccg gaagtagggc gtatcaaacg gttgatgcag cggagtaaag
     9601 tggactttcc actaccggac agccccataa tgacgaatat ttcgccttca ttaatggaaa
     9661 gattcgcatc tttcaccgca actgtacatc cggtcgcttt caatatttca ctttttgttt
     9721 taccttcttt caacatcttc aaagccttct gcttctcatt gccaaaaacc agatagagat
     9781 ctttaatttc tattttactc atacaataaa atggtttagg ttattaaaat aatatacaca
     9841 gcaagacaag aacaaacgat aacaggaatc tttctttata tcgtataaag ttctgattta
     9901 aataagggac aaataacaat gaatcccgaa ataattaata aaatgattat tgacagactg
     9961 agtaattaaa aaaggaatag aatttgataa gataatcctt tcaacgaata gcaaaaaata
    10021 gcatttttat gtataaaaac agcctgttcc agtatcttgc tggcacaaag atacaaaaaa
    10081 cggattaaac atacaaatta tattcaaaat ccggggcata cagagggctt tatttgtaat
    10141 gatatggaaa gtttccgggt aatattcccc tatcactcag caaaatagaa caaaccggca
    10201 gataaatata aaataagttt gaatatttca cttaaacacc gtatatttgg cgtcaataac
    10261 taaactagat ttatatgttc aacagggcta ttacaatttt cctggggaag gataattgtc
    10321 attacacaac aaaagaaaaa caaacaggta ctgccacact agacgacaaa agccaagtac
    10381 agttccttag taaaaagaac cccaaaatgc cgtttttcta tagccggcgg aatctctaca
    10441 tgataggttt cctgctcgct tttatagtga ctctgctcga atttatacga ggacggcatc
    10501 aaaactttat ggtcttctcg gacgctactc aattcttctg gcaaggcatc agcccataca
    10561 caactgaatt tgtagaagct cacggacgct acttccttta ttctccagtt ttcacggtat
    10621 tgttcgctcc gtttgcgtat ctgcctgcat ggctgggacc tttcgcgtgg aatctattca
    10681 attattcgct gttctttatg gcgatcttca cgctgcccca acaattcacc cagcagcaga
    10741 aatgccgtat gttccttttt ctgttactga ttttaggaca aagtttactt tcatttcagt
    10801 ataacataac ggtagcctat ttattcttat tcgcctatac gttattggaa aaagaccgtg
    10861 gatttctggc tgttctgtta atcatgattt cgggatgtac caaagtatat ggaattttcg
    10921 aactggcatt gttgctgtgc tatcctcacg tatggcgtaa ctttggctat gccgttacaa
    10981 tgggcattgt attgcttgca ttaccgttaa taaaaatagc tcctgcagat ttgctcccct
    11041 attatgaaga atggtgccat agtcttgctg ttcatcagtc cgccggagct tatgattcat
    11101 ttttctatgc ccgccccatt gcagcatgga cattgccaca cttccgtgca cttcagatag
    11161 gaatgctcgg cttgctgact ctgctctttt tggggaattt ccgcaaatgg tcgtcttttg
    11221 ccttccgtgc ccaggctttg ggcattctca tgggctgggt agtattactg agtgactccg
    11281 ccgagaagca tacctatatt atcgcattgg caggtttcat gctctggtat tggagcagac
    11341 caacacgtac cgcaacagac aagattctat tttggtgctg ttttgtgctg ttatgtatcg
    11401 ttcctatcga catattcgtc cctgtaccca tcagagattt cattaccagg accttatggc
    11461 ttcatgtatg ggttttcttt attgtatgga tacggatgat atggcttacc ttccttgcat
    11521 ccttcattca tccacgtgcc acaaatgttc tttcagatta acgcatccgt tagctttgaa
    11581 agaaacttct tctgccagca agagttgttt ttgttccacc caaccgggca ccagccttcc
    11641 ggtggaattt acaactctat ggcagggaat ggataattca tccggcactt ctttcaatgc
    11701 acgtcccacc atccgcgagc attggggtgc ccccaacagc aaagcaatac ctccataagt
    11761 agatactttt cccacaggta tctgggatac gacttcgtac acttccttcc gaaaggattc
    11821 ggaaaagctc tctttatcta ctttataatc tttcatatat ccctctttac gatatcaatg
    11881 aaatcatcct ttccttttca ggaaatctgt cgggctctct ccaaactgct ctttatagca
    11941 cttggcgaaa taagaaggtg aactgaaacc gacttcataa ccaatctccg ctacggtcat
    12001 gtccgaagaa gcaagcaaag aagctgcctt cttcaaacgg gcgatacgga gcaattcatt
    12061 cggagagtag ttagtcaatg atttaatctt gcgataaagc tgcacacggc ttagtcccat
    12121 gtctttgccc aagtcctcca cattcaaacc ggagtctccc attttctctt caatcaatga
    12181 cttgaatctt tctacaaaat ccttgtccat atcgcagaca tcttcttttg ccaatgtctg
    12241 cccgtcacca aagaactgtt tcagacgacg gtgagaatcg atcagattgc ggacacgtgc
    12301 cagcaacagc tgtgaactga acggctttga aatataagaa tccgcaccac cgtcatatcc
    12361 ctgaatacgc tgttcgtcca gtgaacacgc tgtcagcaga ataaccggaa tatgacaggt
    12421 ctgtaactca cttttcagcc ggcggcaaca ttcaatgcca tcaatgcccg gcatcatcac
    12481 atcagaaatg atcaggtccg gaacatactt catagcctta cggattcctt cggagccgtc
    12541 tgccgcttca atcaccgtat agtctgtatg caacagcgta tggacatacg aacggatatc
    12601 ctcattatca tcaataatca gtacggacgg tttggaagag tcatatcctt tttccagttc
    12661 ttcctcttct gccaatagaa catctgttgt acgggaatcc gcagaaacaa gggtggtatc
    12721 cggttcggca gcaacagcct cacaagactg tacaggcagt tcaacggtaa agaccgtgcc
    12781 ctgtttctca tcgctctcta cggagatcat accaccgtgc atttctacga aggcttttac
    12841 caatgccagt ccgattcccg aaccggtatg gtgcatatca atcttataga aacggtcgaa
    12901 tacattgcgg atatgttcgg cagaaatcat ggaaccggta tttgccaccg tgaaacgtat
    12961 ccatcgcttg tcctctttac taagggaaga cagacggatg gctattttcc cgttttccgg
    13021 tgtaaactta aaggcattgg acaggagatt gaaataaata cgttccagct tctccatgtc
    13081 tgccagtgta tgataatccg tatccggcat actatcaaaa gaaaaatgga tatgcttctt
    13141 acgggctgcc gcctgaaaag actcattcca tccttcgaaa gaagaaagga catccaccgt
    13201 aaccggagta tattccatct tgccgttttc atatttacgg aaatccaaaa tctgattgac
    13261 caggcgcaaa aggatattca catttcgctg aatcagcatg agcatccggt gctgatctcc
    13321 actcaatgtc ttgtccgcca ataaatgttc taccgggtcg gcaaccaatg tcaacggagt
    13381 acggaagtcg tgagaaatat tggtgaaaaa gaccagcttg gcatgggtag cttcttccag
    13441 ttgatgagag agctgtatca attggtcacg ctgttcttcc agtttgtcac gctgctcttc
    13501 caattgctgc ttctgcttaa aaagctcttt attcaagcga ttcttagagc ggagtgattt
    13561 ataaacgacc aataataagc cggctaccaa taaaaggata atcagactgc cgtataaaac
    13621 gacctgttgt gtagctacct gagagaggta tccaccgata cgtccgttga gcgtttcaat
    13681 ctttttatcg agttcggaga tgtgtgtagt ctgcaactgc atgacgtgtg cgttggtacg
    13741 gtccacaaca gcggtattca tcaccgtttc tttgggatag ggtttcttct ccagaatgtc
    13801 catagccagt tgcagtacct tatcgccatt ggtcggatag ataaaggtgg catccagcac
    13861 actgtccaaa accagttcca gtccgtttcc cttacccggc aaggcatcta tgccgacaaa
    13921 aatcatttcc ttctcccgcc ctgccatctt tgctgcctga taggcacccg gagcgatacg
    13981 gtcattatgg gcatacacag catcaatctt aggatgcctc cgaagcatac tatccatttc
    14041 tatctctgcc ggaccacgtt cccacgcagc atccgcttta tcaatcagct ttatatccgg
    14101 gaatttactg atggcagcca taaatccctg atgccgttcc attgcaggag tcgaaccgct
    14161 caatcctgtc agttctacta tatttccctt ccctttcaga ctggaggcaa tatagtttcc
    14221 taccgaacga ccgatttcat aattatcggc tccgatatag gcagtatatt tatccgaaag
    14281 aatcttccgg tctacaagaa taacggggat gcctttctga taagcttctt ctacaatcgg
    14341 agtcatagga gcagcttcgt tagcggaaat aatcagcaga tcgactcctt cgtccataaa
    14401 ataatggaca tcttccgcct gcttactgtt atcatctcct gccgaacgga tttccaccga
    14461 aacgccatta taaaacattg cttcccgaag aatctcatca ttcatcttat gtcgccatga
    14521 atcatcgctg cattgagcca ccccaatacg aaaatggggt gtatcctgcc ggcaagccgt
    14581 catcccgatt aaaccaaaca gcaccagcat ccacttcaga tatctcatcg tcttcatcca
    14641 tctcatcatt tcatagttct ttctgtaatc caattaagaa caaaaataag aaataatact
    14701 gtaaagttct ctaacttcag ctatttatta ttctaaaaag aaggaaagca gtcctctttc
    14761 agaccatcgg aaagtattaa caaaagtata aagcgtaaaa caaacactta atcaatgtta
    14821 taaaacatag cgttttactt ggataatttg cagatttcac agaagtccgt atctttgcac
    14881 tgtgtttttc atagtattag atttaaggtt aacaaaggtt ggagcaaggc gttgctcctt
    14941 tttttatgcc ctgacctttc atctaccggt tagttttcat cccattcctt ttccagttta
    15001 ccatcaatag tgtagcgttt ccatcgtcct acacggcgac cattcttata ttccccacat
    15061 tcacgaagct ggtcattctt tacataacga gcttcgaacg gtccgttctg ccttccgttc
    15121 acataggtag aagtttccca ataatcaaag cggttgctca ctatcagccg tcgttccttg
    15181 ccatgcaatc tgccggcctg ataggtagct tcatatctca attcaccatt ttccagatta
    15241 tattcacggt ataaaccgtc tttacgatcg ttcttcatat aatattcttt ctgccttacc
    15301 ccacttccgt tggcaaatga gacatggagt ccatcttctt ttccatccag ataggtttca
    15361 atcatcagcg tatctccgct ttcagcaaaa gtagtccacc gaccattctt ctttccattc
    15421 ttataactac ccagtatacg tggcgagcca aacgtaaaca cggacgaata ttcaccgtcc
    15481 tgcaaacctt cttcattgaa ataaacggtc tcatacaaat catatgtacc tttcagaaaa
    15541 gtatactgtt tgcctacctg cttcccgtcc ttgtaattat gctctttccg caaagtaccg
    15601 tcagattcgt acgacagttg cttcccgtgc tctttcccca tccggaagtt tctttcactt
    15661 tccacttttc cggtagtaaa gtaacttttg ctcgtaccgt ccagcttacc ttccttatag
    15721 gacttttctt ctttcagctt accgtcaaac ttggagttaa tcttgaagag gccatccttc
    15781 cgcccttctt tataacttcc ttccgttatt aatatattgt ccacatattc tttgtatccg
    15841 ccatcataaa aaccatcttt aaaagatgcc agcacatagg cggaatgata accatctatg
    15901 atgcgatgtt cgccattcaa tgctttttcc gttttcagtt cctgaaacaa cagtctgcca
    15961 tcgcctacat taacaacaga tacctgatcg atcttatatt ccttttgcgc aaacaaagga
    16021 agagcaagat ataaaaacaa aaatacgttc cagctttttg atctgaggaa gttcgaaatg
    16081 tgtttcataa agtagttttc tctttttgat ttattattta aaaacctgcc gcaaagatag
    16141 gcaatcggct tataaaacaa ggcaagaaag agggggacaa ttagaaaaaa gaacatctgt
    16201 tattatcatt ctaataatta acagattaag tagtaaatca aaacacaggg aagggggaca
    16261 tttactgaaa taagaaacag aaaagaagat gtgtcaaaag caactaaatt cccctccttc
    16321 aggaaggagg agagtttagt tgcttttgac acatttacat ttgcagtatt aaatatcaca
    16381 acaaaatata agtgtatatt tgaaa
//
