LOCUS       c00008_gnlPro..        24613 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DHCJGBOE_25.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:12:52
            Original ID  :: gnl|Prokka|DHCJGBOE_25
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 25233
            Orig. end    :: 49846
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24613
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[35233:39846]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14613
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24613
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24613
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             417..1505
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GCV_T_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_18"
                     /sec_met_domain="GCV_T (E-value: 2e-96, bitscore: 314.6,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 1.1e-24, bitscore: 78.7,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTPFTEKHISLGAKMHEFAGYNMPIEYSGIIDEHLTVCQGVGV
                     FDVSHMGEFWVKGPHALDFLQKVTSNNVAALTPGKVQYTCFPNENGGIVDDLLVYHYEP
                     EKYLLVVNASNIEKDWNWCVSHNTEGAELENASEHMAQLAVQGPKAIQALQKLTSINLS
                     DLPYYTFTHGEFAGEKDVIISNTGYTGAGGFELYFYPEAAMKIWDAVFEAGAEFGIKPV
                     GLGARDTLRLEMGFCLYGNDLDDTTSPIEAGLGWITKFVEGKNFTNRPMLEKQKAEGTT
                     RKLVGFEMIDRGIPRHGYELYSTDGTAIGVVTSGTMSPTRKIGIGMGYIRPEYSKVGTE
                     ICIDMRGRKLKAVVVKPPFRKQ"
     CDS             complement(1597..3123)
                     /locus_tag="ctg8_19"
                     /transl_table=11
                     /translation="MKRLATLFILTILVATAGFAKPKKYKDLSGNIAVKGELTKEYRQS
                     PAGTPVIIRRVVKMKNPGESSNNICYAVEMNGIQETIPLNEMGHIAISAPQTDREFWQQ
                     IYLKNHLYEYFSDRGYKHKLRQEIDEECLEYLDKLNEIAYQEDYIVSYVQGVFSKLNAT
                     TIDSNRGESLNIRIIQSPEPDAFMLPNGSMVISTGLLCTLDSEDELAAVIACELGHFVL
                     DHQVNNIYRAERRAKRAAFWADVFATTASAALDVAYWDDNEDAYAVSLVADIGAIASLL
                     SIPATDRLGMKYKTSQEISSDRLARQLLAFKGYNPDGIASALGKIIGYYNLHQRNKDIP
                     RYGSIGNLQKRIEKAGESHSLSARPYLRTTSDVVSFNASMNYANKRYKETARLIRKNID
                     NRLATDNDYIILVKAEMALSNTEEVNNRCLAMLDKAQEMAGTSPNLDIYKQKILLLMRM
                     NKQAQAADILKEYITLLSAYEGQGIEGTEKEWTNKEIGWANQMLDRISRI"
     CDS             complement(3305..3556)
                     /locus_tag="ctg8_20"
                     /transl_table=11
                     /translation="MKKGIHPENYRPVVFKDMSNGDVFLSRSTCNTKETIEFEGETYPL
                     VKLEISSTSHPFYTGKSKLVDTAGRVDKFMSRYGNRKK"
     CDS             3745..4752
                     /locus_tag="ctg8_21"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTIHDAG
                     KNDYEFLPDGSYQWTAKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTLHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMKVLGARKYPKQVKKGEFYNPWWETLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
     CDS             5035..6045
                     /locus_tag="ctg8_22"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(6516..8366)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_23"
                     /sec_met_domain="Alpha-amylase (E-value: 2.3e-63, bitscore:
                     207.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIASMAEYKVDRNDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPY
                     TSQYDADQMNDGWFVPSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGDNLPMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNE
                     CYDFYKTILNWRKGNDVIAKGSMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPL
                     KFYKEILKNSKQGKDILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(8476..9828)
                     /locus_tag="ctg8_24"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLIDQET
                     PTVPLLYQKGKALKGLGNNLEALSVFQEVVAQDSLNPRAYIEAAECCKSLAKYSEALDY
                     YQNALHINPDNKYARIQYISLLMNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVY
                     DNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAISITEKYRSIDSTNVLV
                     NRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERAL
                     KDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAF
                     QYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDASKAERYLTAYLKTRPKNSKDK
                     VQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_25"
                     /sec_met_domain="OAD_beta (E-value: 3.1e-152, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11597)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_26"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.5e-21, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             complement(11621..12553)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_27"
                     /sec_met_domain="OAD_gamma (E-value: 6.7e-17, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             complement(12585..14138)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_28"
                     /sec_met_domain="CT_Btheta (E-value: 8.3e-291, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(14197..14613)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_29"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.3e-25, bitscore:
                     82.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMHHLAFAVEDGVAGALAEVEEKGIRL
                     IDKAPRKGAEGLNIAFLHPKSTLGVLTELCEKPE"
     CDS             14902..16389
                     /locus_tag="ctg8_30"
                     /transl_table=11
                     /translation="MKKNILLAVCFLMPLATMAQNDTLGHERNITLSEAIVLARTQSVD
                     AAVALNELKTAYWEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGL
                     SGQLSVDQNIWFTGGKLSLTSSLDYLKQLGSGGAKQFMSVPVSLELTQPVFGVNTLKWN
                     RRIEPVRYAEAKAEFISATEEVTMKTITYFFELLLAKESLATAMQNKTNADRLYEVAIA
                     KRKMGQISENDLLQLKLNSLQGKADVTEAESNLNAKMFQLRSFLGVSEQESLNPVLPAT
                     VPDIKMEYDRVLNKALERNSFAQNIRRRQLEADYEVATARGNLRSIDLFASVGYTGQNH
                     EFSSAYRDLLDNQIVQVGVKIPILDWGKRRGKVRVAKSNREVVLSRIRQEQMDFNQDIF
                     LLVANFNNQAQQLDIAEEADVIAEKRYKTSVETFMIGKISTLDLNDAQNSKDEARQKHI
                     SELYYYWYYFYQLRSLTLWDFERDTELEADFEEVVRG"
     CDS             16533..17894
                     /locus_tag="ctg8_31"
                     /transl_table=11
                     /translation="MILIIDDDSAVRSSLSFMLKRAGYEVKTAPSPREAMDIVRAEAPA
                     LILMDMNFTLSTTGEEGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITK
                     PWNNAALLQRIETALELTAAPKEVPEEQTTALNRSHIIGKSKGLMEVLNTVARIARTNA
                     SVLITGESGTGKELIAEAIHINSQRVKQPFVKVNLGGISQSLFESEMFGHKKGAFTDAS
                     ADRIGRFEMANKGTIFLDEIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKVDVRVVSAT
                     NADLRKMVSERTFREDLFYRINLITVKLPSLRERREDIPLLARHFADRQAEVNGLPRTD
                     FSADALNFLSRLPYPGNIRELKNLVERTILVSGKPVLDAADFDAQYLRHDEPAKAAEGT
                     SFAGMTLDEIERQTILQALEQHKGNLSQVAVSLGISRAALYRRLEKYNIQVPCA"
     CDS             17885..19198
                     /locus_tag="ctg8_32"
                     /transl_table=11
                     /translation="VRIKFFFFILVLFLLGLGGMLVYLLSGKPLLYLYVLEGLIGFILI
                     YLIVFYNKIVKPMNTIGSGMELLREQDFSSRLSRVGQYEADRIVNIFNRMMEQLKNERL
                     RMREQNHFLDLLIQASPMGVVILTMDDEVSQLNPMAVKMLGVRMEEAMAKRLDQMDSPL
                     AAELSSIPKDETAVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTEEVMRAEKRAYEK
                     VIRMIAHEVNNTTAGITSTLDTVEQALSTEDDMEDICDVMRVCTERCFSMSRFITRFAD
                     VVKIPEPTLVPVQLNELVSMCKRFMEGMCNDRNIGLRLECDPEVGMVRMDASLFEQVLV
                     NIIKNAAESIEGDAGENGQQGEIIVRTTAPASVEVVDNGPGISKETEAKLFSPFFSTKP
                     NGQGIGLVFIREVLSRHGCTFSLRTYNDGLTRFRILFN"
     CDS             complement(19225..20859)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_33"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-21, bitscore:
                     69.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.0013, bitscore:
                     10.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKLLEKKMESISPFELKNRLIDMADESLKKTARTMLNAGRGNP
                     NWIATAPREAFFLLGSFGLEECRRIMDLPEGIAGIPEKKGIASRFEAFLKKNNNVPGAK
                     LLEQTYNYLLMQHAADPDSLVHEWAESIVGDQYPVPDRILHFTEILVQDYLSQEMCDNR
                     PPRGAYDLFATEGGTAAMCYIFDSLQENFLLNKGDGIVLMVPAFTPYIEIPQLSRYQFR
                     VTKIHANRMNSEGMHLWQYSDEDIDRLKSPKIKALFVTNPSNPPSYTLSPDTMARIVSI
                     VRNDNPNLMIITDDVYGTFSPHFRSFMAEIPYNTLCVYSFSKYFGATGWRNAVIALHEF
                     NLFDKLIAKLPKEKREILHHRYSTLTLEPEKLKFIDRMVADSRQVALNHTAGLSLPQQM
                     QMGLFAAFALLDKENKYKQKMQEIIRRRLHALWENTGFTLTEDPLRVGYYTEIDMLVWA
                     KKFYGDDFVEYLKRTYSPLNVVFRLAKETSLVLLNGGGFDGPEWSVRASLANLDEKDYA
                     TIGQGIKKILEEYAKEFFKNGKAKDKN"
     CDS             complement(21136..22830)
                     /locus_tag="ctg8_34"
                     /transl_table=11
                     /translation="MEWIFNQLRERPELAIFLTIFLGFWLGKLRIGKFTLGTVTSVLLV
                     GVLVGQLNIAVPGPIKSVFFLLFLFAVGYKVGPQFFRGLKKDGLPQVGFAVLMCISVLL
                     VTWLLALMMGYNAGEAAGLLAGSQTISAVIGVAEDTMANMGLDEAQRQSYVNIIPVSYA
                     VTYIFGTAGSAWVLSSIGPKMLGGLEKVKAACKELEAKMGSSLADEPGFMPAARPVTFR
                     AYRVENEWFKNGKRVIDLEVYFRQHDKRLFVERLRKSGVVVEVSMNIQIEPGDEVVLSG
                     RREYIIGEESWIGPEVQDAQLLDFPAEKLPVTITRKTVAGKTVAVIRREKFMHGVSIRS
                     IKRAGISIPVLAQTVVDAGDVIEVVGTRQEVEAAAKRLGYIDRPTNQTDMIFVGLGILV
                     GGLFGALSVHIGGIPISLSTSGGALIAGLFFGWLRSKHPTFGRIPEPSQWVLNNVGLNM
                     FIAVVGISAGPSFVQGFHDVGISLFLVGAAATTLPLIIGLLLARYVFKFHPALALGVCA
                     GARTTTAALGAVQDAVESETPALGYTVTYAVGNTLLIIWGVVIVLLI"
ORIGIN
        1 cacgaccgca cccgcttcga agagcgcaag aaggagatgg aacgtcttgt ggcaaaaatc
       61 aatgaagaat acggtccggg taccgctact ctggaacttc gcgaccaata ctataatatg
      121 cgcgagcaga ttgaaccggt gatgcatatc atcgacaccg cttttgccgc catgaaggcg
      181 gtaggtgtag agcctcgtgt aaaagccatt cgcggaggta cggacggtgc ccagctctct
      241 ttcaagggcc tgccttgtcc caatatcttt gccggtggct tgaacttcca cggccgctat
      301 gagttcgtgc ctatccagaa catggagaaa gccatgaacg tcatcgtcaa gattgccgag
      361 ctcgtagcca gcaaatagat aattcataac tcataactca taactctaat agttccatga
      421 aaaccactcc gtttaccgaa aaacacatct cgctgggtgc caagatgcac gagtttgcgg
      481 gatataatat gcctatcgag tattccggca tcattgacga acatcttaca gtatgtcagg
      541 gtgtcggtgt attcgacgtc tcacacatgg gagaattctg ggtgaaaggt ccccatgctt
      601 tggactttct gcagaaagtg acttccaata acgtagctgc cctcacaccg gggaaagtac
      661 agtatacctg cttcccaaat gaaaatggag gtattgtgga cgaccttctg gtctatcatt
      721 atgagccgga gaaatacctg cttgtcgtga atgcgtcgaa cattgagaaa gactggaact
      781 ggtgtgtgtc tcataacacg gaaggcgcag aattggaaaa tgcttccgag cacatggcac
      841 agcttgctgt gcaaggaccg aaggctattc aggctttgca gaagctgact tccattaatc
      901 tttccgacct tccttactat acttttaccc acggtgagtt tgccggagaa aaggatgtca
      961 ttatctccaa taccggatat accggtgcgg gtggttttga actttacttc tatccggagg
     1021 ctgccatgaa gatttgggat gccgtgtttg aggcaggcgc ggagttcggc attaagccag
     1081 ttggtctggg tgcgcgcgat acgcttcgtc tggaaatggg attctgtttg tatggcaatg
     1141 atttggatga caccacttcg cccattgaag cgggtttagg atggattacc aagtttgtgg
     1201 agggaaagaa cttcaccaat cgcccgatgc tggaaaaaca gaaagcggaa ggcactaccc
     1261 gtaagttggt gggatttgaa atgatagacc gcggtatccc ccgtcatggt tacgagctgt
     1321 atagtacaga cggtactgcc atcggtgtgg ttacctccgg aactatgtcg cctacccgca
     1381 agattggtat cggaatgggg tatatcagac ccgagtacag caaagtcggt acggaaatct
     1441 gcattgacat gcggggacgt aagctgaaag ctgtggttgt gaagccgccg ttccgcaaac
     1501 agtaatttga atgaataact aaaataagaa gaatgaagaa tttgtcatgc ggcatcatcg
     1561 cgcagtcaaa ttcttcattc ttagttattc ctttctctat attctgctta tcctgtccag
     1621 catttggttt gcccaaccta tctctttatt ggtccattcc ttttcggttc cttctatgcc
     1681 ctggccttcg taggccgaaa gcaaggtgat atattctttc agtatatcgg cggcttgggc
     1741 ttgtttgttc atgcgcatca ataatagtat tttttgttta tatatgtcca gattggggct
     1801 tgttcctgcc atctcctggg ctttatcaag catggcgagg cagcggttgt tcacttcttc
     1861 cgtattagac agtgccattt ccgcttttac caggatgatg tagtcattgt ctgtggctag
     1921 tctgttgtca atgttcttgc gtatcagccg ggcagtttcc ttatagcgct tgttggcgta
     1981 gttcatactt gcgttgaaag aaacgacatc gctggtggtc cgtaggtagg ggcgggcact
     2041 caggctatgg gattcaccgg ccttttctat acgcttttgc aggttgccga tgctgccgta
     2101 gcgaggaatg tccttgttgc gttggtgcag gttgtaatac cctataattt taccgagggc
     2161 cgatgcgatt ccgtcgggat tatatccctt gaatgccaga agttggcgcg caaggcggtc
     2221 tgaagagatt tcctgggaag ttttgtattt catccccaac cggtccgttg ccggaatgct
     2281 caaaagggaa gcgatggctc cgatatctgc caccagactg acggcataag catcttcatt
     2341 atcgtcccag taggccacat cgagggctgc actggcggta gtggcaaaga catctgccca
     2401 aaaagctgca cgcttggcac gccgctcggc acggtaaatg ttgtttacct gatggtcgag
     2461 gacgaaatgt cccagctcac atgcgatgac ggcggccagt tcgtcttcgg aatcaagagt
     2521 gcagaggagg cccgtactga taaccatgga gccgttggga agcatgaagg catctggttc
     2581 gggcgactgg atgatacgta tgttcagact ctccccgcga ttgctgtcaa tggtggtggc
     2641 gttcaacttg gagaacactc cctgcacgta cgaaacgatg taatcttcct gataggctat
     2701 ctcattcagt ttgtcgagat actccaggca ctcttcgtcg atttcctggc gcagtttgtg
     2761 cttgtagccg cggtcgctga aatattcgta aagatggttt ttcaagtata tctgctgcca
     2821 gaattcccgg tcggtttgcg gagcggatat ggcaatgtgc cccatctcat tcaaaggaat
     2881 ggtctcttgt atgccgttca tttcgacagc atagcaaatg ttgttgctgc tttcaccggg
     2941 attcttcatt ttgacaaccc ggcggataat gaccggtgta ccggcgggag attgccggta
     3001 ctcttttgtc aattctcctt tgacagcgat gtttccgctt aaatctttgt actttttggg
     3061 cttggcaaat cctgccgttg cgacaaggat tgtcaggatg aatagggtgg cgagtcgttt
     3121 catgattagt atatgttttc ggttttgatg atacaaaaat agggaagtgt ttttctcctt
     3181 tctcgttttt ttccctattc tgtgatagga gattccctat ttatcggtcc tgcagtggga
     3241 ggcggaaaca aaaaagggaa cctttcagtg aaagactccc ttttttcagt ttgcttgaaa
     3301 ctgattattt cttacggtta ccgtaacggc tcatgaactt atcaacacga ccggcagtgt
     3361 caaccagctt agacttacct gtgtagaacg ggtgagaagt gctggagatt tccagcttta
     3421 ccagcggata agtttcacct tcgaattcga tagtctcttt cgtgttgcaa gtggaacgag
     3481 acaagaatac atcaccattt gacatatctt taaatactac cggacggtaa ttttcaggat
     3541 gaataccttt tttcattttg atattttctt ttaaaaattt atattctgtt actattttgg
     3601 taataaatag tgtaatggtc ttcttttcag agcgcaaaga tagtgcaagt tggagactct
     3661 acaaaataaa ttcagattta tttttattta gtaggtttat cgcattttat ttctgatttt
     3721 tgcaggactt aatcttgtga atttatgagg aaactacttg tcttatgctc tttctggctg
     3781 tgcgtggcaa cgttgggggc acaaaatgcg gaacggaaac tgtatagtgt tgcgttctac
     3841 aatcttgaga acttgtttga tacgattcat gatgcaggta agaatgacta tgagttcctg
     3901 cccgacggca gttaccaatg gacggcaaag aagtatgagt ccaagctgca gaacctttcc
     3961 aaagtgttgg gttccctttc gcgtgattta gtgccggaag gtccggcatt catcggtgtg
     4021 gcagaggcgg agaacagccg ggtgctggaa gacctcgtga agcagccggc catttccaat
     4081 tatgagttcg tgcattatga aggaccggac agacggggta tagactgtgc cttgctgtac
     4141 gacccgaagc agtttagcgt tacccactca aagttggtgc tttctactcc ttttgagggg
     4201 gatacgctgc acttgacgcg cggcttcctg attgtggacg ggcaactggc gggagagcgt
     4261 gtctgcgtga tagtgaacca ctggccctcc cgtggggcaa agtcaccggt gcgtgtgcat
     4321 gcagccaggc aggtaaaggc cttgaaggac tctctgatgc gtagcgacaa gaagctgaaa
     4381 ctcatcgtga tgggggatat gaatgacgac ccgatggatg aaagcatgaa ggtgctgggt
     4441 gcacgcaaat atccgaagca ggtgaagaaa ggcgaattct acaatccctg gtgggagaca
     4501 ctggaagaca agggagtggg gacattgctc tatcggggca agtggaactt gtttgaccag
     4561 attgtcattt cgaaaccgtt gctgaaggct aagaaagggt tgcgctatga tcacaatgaa
     4621 gttttcatcc gcgattatct gattcagcag gatggcaaat acaaaggttc ccccttgcgt
     4681 acgcatggag gcaggacttg gctgaacggt tacagtgacc atttgccgac catcatctat
     4741 ctgaaaaatt agtattacat aataatgtgt aaacagatgc cggagagcaa acatgttctc
     4801 cggctttttt gttgatagaa gtatagatgg caaaagtatg gctggcagag ataaatgcaa
     4861 agagtttgta atatagagat tacaataatc tgttaaatga agccaatagc tttaaaatag
     4921 aatggatttg gtaggatgag ccggatattt tattcctctc aagttcttta ctttaaagga
     4981 taatgattac ttttgcgtag aattttaatt cactaacaat aaaatttaaa caaaatggtt
     5041 aattacaaag atttaggact ggtaaacaca agagagatgt ttgctaaggc tatcaaaggt
     5101 ggatatgcta ttccggcatt caacttcaac aatatggaac agatgcaggc tatcatcaag
     5161 gctgcagttg aaacaaagtc tccggttatt cttcaggtat ctaagggtgc ccgtcagtat
     5221 gccaacgcta cgctgttgcg ttacatggct cagggtgctg ttgagtacgc taaggaattg
     5281 ggttgcaaac atcctgaaat tgttcttcac cttgaccacg gagatacatt cgaaacttgc
     5341 aagagctgta tcgactccgg tttctcttca gtaatgattg acggttcaca ccttccgtac
     5401 gaagaaaacg ttgcactgac taagaaggta gttgactatg cccatcagtt cgacgtaact
     5461 gtagaaggcg aactcggtgt attggccggt gtagaagatg aagtttctgc agaacaccat
     5521 acatatacta atcctgaaga agttattgac ttcgctaccc gtacaggttg cgattcactg
     5581 gctatctcaa tcggtacttc tcatggtgca tacaagttca aacccgaaca atgccacgtt
     5641 gaccctgcta ccggtcgtct ggttcctcct cctttggaat ttgccgttct ggatgctgta
     5701 atggagaaac ttccgggatt ccccatcgtt cttcacggtt cttcttcagt tcctcaggaa
     5761 gaagttgata ctatcaacaa gtatggtggt aagctggaag ctgctatcgg tatccccgaa
     5821 gagcagttgc gtaaggctgc caagtctgct gtttgcaaaa tcaacatcga ctctgactca
     5881 cgtctggcta tgacagctgc tatccgcaag acatttgctg aaaaaccggc agaattcgac
     5941 ccgcgtaagt atctgggtcc ggctcgtgac aatatggaaa aactgtacaa gcataaaatc
     6001 atcaacgtgc ttggttcaga gaacaaattg gctcaactgg actaatcgaa agataatccg
     6061 aatatagcgt cagcccttgc aatattgatg ttgcaagggc tgacttgttg tatataggcc
     6121 ggtgttgtgg gatggttaag ttcgccgctt atttcagaag cggatgtttc aacgtgtaca
     6181 acagtctgtt tcctttaaca aaacagtctg tttcccttaa ctgaacagtt tgtttcaata
     6241 aagagaacac tttgttccaa tatgcaaaaa cacttcgttc caatacgtaa gaacactttg
     6301 tttctacata tctgaacact ttgtttctct atactggaac aaagtgttca ccgttatgaa
     6361 ctaacagatt agctatattt gagaccggtg aaaagcatat ccccgtgaca cctattccat
     6421 actaaaaatc ccttgcagat ggctggcagg agaagtgtct gccagctatc tgcaagggag
     6481 atttgcaaga atgagctctc tgtgtggagt acgcgttata attctatcac taatgattct
     6541 ctggggccca tcttcagctc ttcaccgaag gtgatggcct tgccgctaag aatatctttt
     6601 ccctgcttgc tgtttttcag gatttccttg tagaatttca aaggaacggt ggtctctgca
     6661 tctgtaccgt tcagcatcac gaatatcgtc ttgccttcgt actggcgtgc gtaggcataa
     6721 acaccattct gtaccatgaa ctgcaccatg ctgcctttgg caatcacatc gtttcctttg
     6781 cgccagttca ggatggtctt gtagaagtcg tagcactcgt tctgtatttt ggtacgtccg
     6841 gctggggtca gtgcgtttgt tgcgtcaccg gtccatccac cggggaagtc cttgcggaca
     6901 tagccgtcgc tcttgctctt cacgccattc atcataactt ccgttccgta gtagagttgc
     6961 ggaatgcggc gggtggtaag cagcagggta gaggcttgct tcagcatcgg aaggttgtcg
     7021 ccttcgccca ggaagcggtc ggtgtcgtgg ttttcgatga atgccagtac ggaagcgggg
     7081 ttggggtaga ggaagtcgta tacgaagtta ttgtatatgc ggtctagtcc cttgaaccaa
     7141 gtttcggtct gttcattctt ggcggtattt atcttgtcga agaagctgaa gtccataacg
     7201 gtcttgaggt tactgttctt gggggctgat agcttggaat ccttctgcca ccaggcggtg
     7261 taggcgggtt cggtaaccca ggtctcgccc acggtgttgt agttgggata ttcttcgttg
     7321 agctctttca tccagttgct catggcatca tagtcggcat acgggtaagt gtccatgcgg
     7381 atgccgtcga tgttggcgaa ttcaatccac cagaaactgt tctgtaccag gtagcggtaa
     7441 acgtgaggat tcttctggtt gaggtcgggc atggaaggta caaaccagcc gtcgttcatc
     7501 tggtcggcat cgtactggga agtataaggg tctacgtgcg gggtcagttt gaaggaggtc
     7561 tgcacgaagt tgttttcgtg gtcggggttg ttgaaccaat ctttggaggg catgtcctta
     7621 atccatacat gctctacgcc gcagtggttg aaaatcatgt ccattacgat tttgatgccg
     7681 cgtgcatggg ctttttcaat cagttgcttg tattcttcgt tggtaccgaa gcgcgggtcc
     7741 accttgtagt agtctgtggt ggcatagccg tgataggaac cgccggtcat gttgttttcc
     7801 agtaccggag taaaccagag ggctgtgacg ccgaggtcgg agaagtagtc caggtgttgt
     7861 tctatgccgg caaggtcacc gccgtggcgt gcattggggt cattgcggtc taccttgtac
     7921 tcggccatgc tcgcaatctg gtcattgtct gggttgccat tggcaaagcg gtcgggcatc
     7981 agcaggtaca gtgcgtcgga ggcgtcgaaa cctttatgtt cgcaaccttt cttgttgcgt
     8041 gccttcagtt catattcctt tacgagtttc ttttttcctt cagtgaaggt gaggttgaat
     8101 ttgccgggtt ttacatcctt gtccagtttc agatagacca ggaggtagtt gttgctttcc
     8161 agcttgacgg tgctgctcaa tgagacgcca ggataattga cggatactgc cgcgttgccg
     8221 atgccttcgc catagaccat cagctggagt tccgggttct gcatgccggt gtaccaaaac
     8281 ggagggtcga ttttgttcac attcatagct gcatacgtac tgagggagag taagagtgtt
     8341 cccaagatta agaatacttt tttcatgata gtaactttac ggttaatttt tgcgctaatt
     8401 taaaacaaat aacggagaaa gttaatcttt ctccgttact gtaccttatt atattatgca
     8461 aacgttttca ttgggctatt tgatgggggt tacgctggcg gtatcgacct ttcccttgaa
     8521 gaagtcctct ttcttgcgct tttctctgat gtccttcagc cagttttcgg cggcattgta
     8581 tcggttgtct tctccgatga tgggaactcc gtccgcatct acttcctgca ctttgtcctt
     8641 gctgtttttc ggacgggttt tcaggtaggc cgttaggtat ctctctgctt tggacgcatc
     8701 tttcagatag taataataga taaaggctgc gtcgtagagc agtttgtgtt tctgccggtc
     8761 gtatttttcg tattgcgtca gaagggtatt cgcctggtcg gtgtattgaa atgccatctt
     8821 gtagcagtcc gcaagcccca catataggcg ggacatgaca ctgtcgctgg gcatggcgag
     8881 gcttacggca gtttctagat aagtcactcc atcctctttc catgatgtct tggagcaggc
     8941 gcgtcccaga taatagagaa cgttgatgtt ggtattgtca tctttaagag ccctttccag
     9001 caggtcgtgt gctgggtaga agtcttcgag ggcataataa ctgattccgg cgtagaagca
     9061 ggtttggaaa gaactgtctt tttcctgtaa cagttgttca tatctttcta ttgctttggg
     9121 gtaatctttg ttcaggcaat aggcttgggc attgatgcgg ttcacaagga cgttggtgga
     9181 gtctatggaa cggtatttct ccgttatgct tatggcgtct tcatactggt ggcctgctac
     9241 atagatgttg ccgagtttgg cagcagacag gtaatcattg ggatatcttt tctgtatgtc
     9301 cagataggca tctatcacat gcatgatttc tgtgttgtca tagacttgcc ccatactttc
     9361 ggctctaagg tgtagtacat aggcggaact gtccctttct gccagcaggt tactttcctt
     9421 tagagactca cggtatctct tcatgttcat cagcagactg atatactgga tgcgtgcgta
     9481 tttattgtcc ggatttatgt ggagcgcatt ctggtagtaa tccagtgcct cgctatattt
     9541 ggctagtgat ttgcagcatt cggcagcttc aatgtatgcc cggggattga gagaatcctg
     9601 agctacgact tcttgaaata cgctcagagc ttcaaggtta ttgcccagtc ctttcagcgc
     9661 tttccctttt tggtagagca gggggacggt cggggtttct tgatcgatca acatcaaggc
     9721 tgtttcataa tcgtagttgg ccatcgcctc ttgaatgggg tttgtggtct gtgccgccag
     9781 aagtgaacag catgcactga aacataagga gataaaaagc tttcgcatac agtatatcat
     9841 ttatatgagg ttaaactgac tgcaagttac taaaaagaat gtatttacga aataatcgta
     9901 atctgtttta gatagattaa cgaaaaagcc cctccaaaaa tgatggaggg gctttaaaat
     9961 agttcggaat tcaatccgga taacggaatg aataaatgta ttacattaag aatcccagca
    10021 ggatacctgc tgctacagcg gaaccgatta caccggcaac gttcgggccc atggcatgca
    10081 tcagcagata gttggtagga tcgtattcca gacctactac ttgggagata cgtgcagagt
    10141 cgggtacggc agatacaccg gcattaccga tcaacggatt aatcttgttg cccttcttca
    10201 ggaagaggtt gaaaatcttc acgaagatga cgccggatgc tgtggcaatg acaaatgata
    10261 aggcgcccag accgaatatc ttgattgaat caagggttaa gaactcggat gcttgcgtag
    10321 aagcacctac tgtcaaacca agcagaatag taatggtatc aatcagtgga ccactggctg
    10381 tgtttgccag acgacgtgta actccacttt ctttcagtaa attaccgaag aacagcatac
    10441 ccagcaaagg cagaccggat ggtacaagga atgtggttag taacaaaccg ataatcggga
    10501 acattacttt ttccgtatgt gaaaccacac ggggaggttt catacggata agacgttcat
    10561 ttttactggt cagccaacgc ataataggcg gctgtatcac cggtactaat gccatatatg
    10621 aataggctga taccgcaatg gcacccatta agttaggagc cagtttggaa gagaggaaga
    10681 tggcagtcgg accatcggca ccaccaatga taccgattgc accagcctgc atcgggtcaa
    10741 atcctatggc aagggcaatc atataagcac cgaatatacc gaattgggct gctgcaccaa
    10801 ccaacattaa tttggggttc gatatcaaag cagagaaatc cgtcatggca ccgataccca
    10861 ggaatatgag tggcgggtac caaccggagg ttactccctg gtacagaata ttaagtacgg
    10921 aaccttcttc atagataccg acttttaatc cggcttccat attgaaaggt atattaccaa
    10981 tcagcatacc gaaaccgata ggaattaata gcatcggctc aaattccttg gctacagcca
    11041 agtatatgaa aaacaaacct accagaagca ttaccacatg tcctaccgtt gcattggcaa
    11101 aacctgtata agtccagaag tcggcaaggt tgtttcctaa aaatgtgata aattctccca
    11161 tattattcaa taattacgag gtcagtacct tcgagaacag agtccccttt gtttacattg
    11221 atggctgtaa tcttaccgtc tttatcagca ttgatattgt tttccatctt catggcttcc
    11281 agaatgatga taacttgtcc cttctttact gtatcgccga catttacttt gatatcgagg
    11341 attacaccgg gaagcggaga ttttacacct gacttgccgg tagaagcagc ggccggtttt
    11401 actaccggag tagcaggagc agcaggagcg gatgtggctg ccggacgtgc taccggttta
    11461 acgactacct tcggtgcttt ttccatttca actttgtagg gagtaccgtt cacttctaca
    11521 tgagcgatgt tgtcttcaat atctccaatg gcaactttat atacgttacc gttaatttta
    11581 tatttatatt ctttcatcgt tttattttat tatgggtgac ttactttttg tgaggagtct
    11641 cacgcaacgt ataaatcttt gaactccacg gtgagtaact gcgttttaca cgggtaatgg
    11701 taagtatcgt gtcttccaca tcgtgtacat cgctttggaa ttcgtgcatg gccattgaaa
    11761 tggcagcaaa aacttctccc ggagcctgcc ccagttgttt ctcttttgct tcttgtttat
    11821 cagtaatacc tttagctttc atggcattgc gtttgctgag gttaactgat attttaccta
    11881 taatcttgaa ggagatgtag agtaatatca gcccgcagaa tacaacgctc atggcagaaa
    11941 tagccatacc gatacctacg ctgtcatgct cttcgaattt ttccattttg gcattgctgt
    12001 cgatagtctt gttgttggta ctcggagtga catatttatc ttcgcttcca ccctttactt
    12061 cccattggtc ggctgcatca ctgacacggg cataggattg gttggctttt aaagtaccgg
    12121 caggcactat gacttgatca agcaatttct tgccggaatc atacaaccca atccagttgg
    12181 catttgtggc atccagtttg aagttcgtat gaaatgtacc gcgtcttggt tctccatcag
    12241 cccagaaaag tgcatgctga cgtggtttta tgagtgtcag aacgtcacct ttgggaatga
    12301 aataactggc agtatcaccc ggctggctgc tgaatttcag atagcaacct gcaaggtcgg
    12361 cgctgccgta tgatctgttg aatatttcaa tccatgcgct gtgcacaccg tagtcatcct
    12421 gatagttgct ctcgttgttg accagcactt cattcagcag cagtttgttg ttcgatttct
    12481 gttctttgca agaagagcaa aagcccaaca ccagcatcaa tgaaaggaat attccgattt
    12541 ttgttttatt cataatcgtt cttgttttag tgtgaaaagc ttgattacaa gggaatatta
    12601 ccatgcttct tagccgggtt agtcaatttc ttggtttgca actgttgcag ggcacgaatg
    12661 atgcggaaac gtgtgttacg cggttcgata acatcatcaa tgtagccata tttagctgca
    12721 ttataaggat tggcaaacaa cttggtgtat tcagcctctt tttcagccag gaattgagcc
    12781 ggattttcct gctctttggc ttcgcgggca tataatactt ctacagcacc tgcaccaccc
    12841 attacagcga tttcagcagt aggccaagca taattcatgt cgccacgcag ctgcttacag
    12901 ctcatcacga tgtgcgaacc accgtaggac ttacgcagtg taatggtaac cttgggtaca
    12961 gtagcttcac cgtatgcata cagcagtttg gcaccgtgca ggatgacgcc gttgtactcc
    13021 tggccggttc ccggaaggaa tcccggtacg tctaccaatg atacgatagg aatattgaag
    13081 gcgtcgcaga aacggacgaa gcgtgcgccc ttgcgggatg cgttgctgtc gagcacacct
    13141 gccagatact tcggctggtt ggcaacgata cctacggact gtccgttgaa acgtgcgaaa
    13201 ccgataatga tattctttga ataatctttt tggatttcga ggaactcacc attatctatg
    13261 atagcgccaa ttacctcgta catatcgtac ggtttgttcg ggttatcagg aatgatgtcg
    13321 ttcagggaat cttccagacg gtcgataggg tctgtgcagt ctacataagg agcttcttcc
    13381 aggttgttct ggggaatgta gctcaacagt ttgcggataa gggccaaacc ttcttcttct
    13441 gtctgtgcag taaaatgagt aacaccagat ttggtggagt gaacgctcgc gccacccagg
    13501 ttttcctggc ttacgtcttc tccggttaca gtctttacta ccttcggacc ggtaaggaac
    13561 atgtaggatg taccttccat catcaaagta aagtctgtca atgcaggaga gtaaacggca
    13621 ccaccggcac aaggaccgaa aataccggaa atctgcggga tgacaccgga agcaaggatg
    13681 ttacgttgga agatttcagc gtagccagcc aaggcattga taccttcctg aatacgtgca
    13741 ccgcccgagt cgttgatacc gatacacgga gcacccattt tcatggcttg gtccataatc
    13801 ttacagattt tcagagacat ggtttcggac agtgaaccgg cagaaactgt gaagtcctgt
    13861 gcgaagatat aaaccagacg gccttcgatt gtaccgcaac cggttactac accgtcaccg
    13921 gggtagtgtt tcttttccat gccgaagttg gtgcatctat gttctacgaa catgtccatt
    13981 tcttcgaaac tgccttcgtc aagaagcatg gctatacgct cacgagctgt atatttaccc
    14041 ttctcgtgtt gctttgcaat cgctttttca ccaccaccga gacgtgctgc agcgcggcgg
    14101 tctataagct ctttaatctt ttcaagttga ttactcatga atttatattc tttaagtgtt
    14161 tatacaattt atgatttgat gattttacag tcttgcttat tccggtttct cgcaaagctc
    14221 ggtcaggaca ccgagagttg acttcggatg caggaatgca atgttcagac cttctgcacc
    14281 tttgcgggga gctttgtcta taaggcggat acctttttct tcgacttcgg caagcgcacc
    14341 ggccactccg tcttcaacgg cgaatgcgag atgatgcatg ccaccgttac cgttgttctt
    14401 ttcgatgaac ttggcaattg tgctttcggg agaagtaggt tccaacaatt cgatctttac
    14461 atcgcccact ttcaggaaag cggttctaac tttctgatct tccacggttt cgatgttgta
    14521 gcatttcaaa cctaaaacgt tttcgtagta cggaagggct tcttcaatgc tcttaacggc
    14581 aatgcccaga tgctcaatgt gtgaaatctt cataactata taaattaatg ttagtattgt
    14641 atccttttaa taaaggtata aagcagcaca aagaaagaga attcttcctt aataaagaaa
    14701 tttttcatca attaattaat ggttaattga actttagaag gattttttca gactttagat
    14761 agagaccggt tgttttcttg atatcgtccg ctaacggaca tccccactgt ccgaaaatga
    14821 acacttaccc ctctatgaaa cctttccggc cacttggcac actctttgct tttctgtttg
    14881 cgacaatttt aaagattgaa catgaaaaag aatattttac ttgcagtttg ttttttgatg
    14941 ccgttggcaa ccatggcgca gaatgatact ttgggacatg aacgcaatat tacgctgtcg
    15001 gaggccattg tactggcccg tacgcagtct gtggatgctg ctgtggcatt gaatgaattg
    15061 aaaaccgcgt attgggaata ccgtacattc cgtgcggact tgttgccgga agtgaatttc
    15121 accggtacac tacccaacta taacaagtcc tacagtacct accagaattc cgacggctcc
    15181 tatagctttg ttcgcaacaa tacactgggg ctgtccggac agctttcggt agaccagaac
    15241 atttggttta cggggggtaa gctgtcactg acttcttcgc tggattatct caaacaactg
    15301 ggttccggag gagcgaagca gttcatgtca gtccccgtga gtctggagtt gacgcaaccg
    15361 gtcttcggag tgaatacctt gaagtggaac cgccgtatag agcccgtacg ctatgccgag
    15421 gcaaaggccg agttcatttc agctacggaa gaggtgacga tgaaaaccat cacttatttc
    15481 tttgagttgc tgctggccaa agaatcgctc gctaccgcca tgcagaacaa gacgaatgcc
    15541 gaccgccttt atgaagtggc catagccaaa cgtaaaatgg gacagatatc cgagaatgat
    15601 ttgttgcagc ttaaactgaa ttcattgcag ggcaaggccg acgtgactga ggcagagagc
    15661 aacctgaatg caaaaatgtt ccagctccgt tctttcctcg gggtgtccga gcaggaaagc
    15721 ctgaatccgg tgttgcccgc cactgttccc gatataaaga tggagtatga ccgtgtgctg
    15781 aacaaggcac tagaacgcaa ctcctttgca cagaacattc gccgccgcca gctcgaagct
    15841 gattatgaag tggcaacggc acgcggaaac ttgcgcagca tcgacctctt tgccagtgtg
    15901 ggctatacgg ggcagaacca tgaattctct tcagcctacc gggacttgct tgataatcag
    15961 attgtgcagg taggcgtcaa gattcctatc cttgactggg gcaagcgccg cggcaaggta
    16021 agggtggcaa agagcaaccg tgaagtggtc ttgtccagaa tccgtcagga acagatggac
    16081 tttaatcagg acatcttttt gctggtggct aacttcaaca accaggcgca acagctggac
    16141 atagccgaag aggcggatgt cattgctgag aagcgttaca agaccagtgt agagaccttt
    16201 atgataggta aaatcagcac cctggacctg aacgatgcac agaactctaa agacgaagcc
    16261 cgtcaaaagc atatttcaga gctgtactac tattggtatt acttctatca gctccgcagc
    16321 ttgacccttt gggattttga acgcgatacg gaattggaag ctgattttga agaggtggta
    16381 agaggataag tcgacgggtt gcaagtgata agttatgagt tatttgccgg taaaagtacc
    16441 gtatatgcga tattataggt aaataactta taacttatca ttcataactc tgctttttta
    16501 cttatttttg cgggaaacaa actacaattt ttatgatact gataatagac gacgatagtg
    16561 ctgtgcgctc ttccctcagc tttatgctga agcgtgccgg atatgaggtg aaaacggctc
    16621 caagtcctcg cgaagctatg gacatagtga gggccgaagc tcccgccttg attttgatgg
    16681 atatgaactt cactctttcc actaccggag aagagggact taccttattg aagcaggtaa
    16741 aggtgttccg tcccgatgtg cccgttattt tgatgacggc atggggaagt atccagcttg
    16801 ccgtgcaggg tatgcaggcc ggcgcattcg atttcataac caagccttgg aacaatgctg
    16861 ctcttttgca gcgcatcgag acggcccttg agcttacggc cgccccgaaa gaggtgccgg
    16921 aagaacagac taccgcattg aatcgcagcc atattatagg taagtccaaa gggttgatgg
    16981 aagtgttgaa cacagtggcc cgcatagccc gtaccaatgc ttcggtgctg attacgggcg
    17041 aaagcggaac gggcaaggag ctgattgccg aagccatcca tatcaacagc caacgtgtga
    17101 agcagccttt tgtcaaggtg aaccttggtg gcatctcgca gagcttgttc gagagcgaga
    17161 tgttcggcca taagaaaggg gcgtttaccg atgccagcgc cgaccgtata gggcgttttg
    17221 aaatggcaaa taaaggtact atcttcctcg acgagattgg tgacctcgac ccttcctgcc
    17281 aggtgaaact gctgcgcgtg cttcaagacc agacattcga agtgctgggc gatagccgtc
    17341 cccgcaaagt cgatgtacgc gttgtgtccg ccactaatgc agacctccgc aagatggtgt
    17401 ccgaacgtac tttccgtgaa gacctttttt accgtatcaa cctgattacc gtaaaactgc
    17461 cctccttgcg ggagcgccgt gaagatattc ctttgctggc acgtcacttt gccgaccgtc
    17521 aggcagaggt gaacggcttg ccgcgtacgg atttctcggc cgacgctctg aatttccttt
    17581 cccgcctgcc ttatccgggc aacattcgtg agttgaagaa tctggtggag cgtaccattc
    17641 tggtcagcgg caagccggtg ctggatgccg cggatttcga tgcccaatat ctgcgtcacg
    17701 acgaaccggc caaagctgcc gaaggtactt cttttgcagg tatgaccttg gatgaaatag
    17761 agcggcagac tatcttgcag gcgttggaac agcataaagg gaatctcagt caggtggcag
    17821 tgtcattagg catcagccgc gctgcgcttt acagacgttt agaaaaatat aatattcaag
    17881 tcccgtgcgc ataaaattct ttttcttcat acttgtcctt tttctgctcg gtctgggtgg
    17941 aatgctggta tatttgctga gtgggaagcc gcttttgtat ctgtacgtat tggaggggct
    18001 catcgggttt atccttatct atctgatagt attctataat aagatagtga agccgatgaa
    18061 caccataggc agcggtatgg agttgctgcg cgagcaggat ttcagtagtc gtctcagccg
    18121 ggtagggcag tacgaagcag accgcattgt gaatatcttt aaccgaatga tggagcagct
    18181 caagaatgaa cggttgcgca tgcgcgagca gaatcacttc ttggatttgt tgattcaggc
    18241 atctccaatg ggggttgtta tcctgacaat ggacgatgaa gtgtcgcaac tgaatccgat
    18301 ggcggtaaag atgctcggtg tccgtatgga ggaggcgatg gcaaagcggc tggaccagat
    18361 ggattctccg ttggctgccg aactttcgtc cattcccaaa gacgagacgg cagtggtccg
    18421 tctcaatgat gcgaatattt ataaatgcac ccattcttct tttattgaca gagggttcaa
    18481 acatcctttt ttcttgatag agcgtatgac agaagaagtg atgcgtgccg agaagcgtgc
    18541 ctatgaaaag gtaatccgca tgatagctca tgaagtgaac aataccactg cgggcatcac
    18601 ttccacactc gatacagtgg agcaggcact ttctacagaa gatgatatgg aggacatctg
    18661 cgacgtgatg cgcgtctgta cggagcgttg tttctcgatg agccgtttca ttacccgttt
    18721 tgcagatgtg gtaaagatac ctgaacctac cctggtgccc gtccaactga atgagttggt
    18781 gtccatgtgc aagcgtttca tggaaggaat gtgcaatgac cgcaatatag ggctacgtct
    18841 ggaatgcgac ccggaggtgg gaatggtgcg tatggatgct tctctttttg agcaggtgct
    18901 tgtgaatatc atcaagaatg ctgccgaaag tatagagggg gacgccggag aaaacggaca
    18961 gcaaggtgag ataatagtaa ggaccactgc ccccgcttct gtggaagtcg ttgacaatgg
    19021 tccggggata agtaaagaga ccgaagctaa actcttcagt cccttctttt ccaccaagcc
    19081 gaacgggcag ggaattggcc tggtgtttat ccgggaagtt ttgagccgtc atggttgcac
    19141 gttctcccta cgtacctaca acgatggatt gacccgcttc cgtatactat ttaattgaaa
    19201 tttgaaagtt ttacctttca cctttcaatt tttatctttc gcctttccat ttttaaagaa
    19261 ttcttttgca tactcctcca gtatcttttt aatgccttgg ccgatggttg catagtcttt
    19321 ctcgtccaga ttggcgagtg aggcgcgtac gctccattcg gggccgtcaa aaccaccgcc
    19381 gttcagcagc accagagagg tttctttggc aaggcggaag actacgttca gcgggctgta
    19441 ggtacgtttc agatattcta caaagtcgtc cccatagaac ttctttgccc aaaccagcat
    19501 gtcgatttct gtataataac ctacgcgcaa cgggtcttcc gtcagcgtga aaccggtatt
    19561 ttcccaaagg gcatgcaatc ggcggcggat aatctcctgc atcttttgct tgtatttgtt
    19621 ttccttgtcc agcagggcaa aggcggcgaa aaggcccatc tgcatctgtt gtggcaatga
    19681 cagtccggcg gtatggttca gtgccacctg acggctgtcg gcaaccatac ggtcgataaa
    19741 cttcagtttt tcaggttcca gagtgagggt ggagtagcgg tggtgcagaa tctcccgttt
    19801 ctctttcggc agtttggcta tcagcttgtc gaacaggttg aattcgtgca gggcaatgac
    19861 cgcattgcgc catccggtgg caccgaagta tttggagaat gaatagacgc aaagcgtatt
    19921 gtagggaatt tctgccatga acgaacggaa gtgcggactg aatgtaccgt atacgtcgtc
    19981 tgtaataatc atcagattag ggttgtcatt cctgacgatg ctcacgatgc gcgccattgt
    20041 atccggactg agtgtgtagc tgggcggatt actgggattg gtgacaaaga gggccttgat
    20101 tttagggctt ttcaagcggt ctatgtcttc gtcgctgtac tgccagaggt gcatcccttc
    20161 gctattcatg cggttggcat gtattttggt cactcgaaac tggtagcggc tgagttgtgg
    20221 gatttcaata tagggggtaa aggcaggaac catgaggacg ataccgtccc ctttgttcag
    20281 caggaagttt tcctgcaggg agtcgaagat gtagcacatg gcggctgttc caccttcggt
    20341 ggcaaacagg tcataggcac cccggggagg acggttgtcg cacatctctt gcgaaaggta
    20401 atcttgcaca aggatttccg taaaatgaag gatgcggtcg ggcacgggat actgatcgcc
    20461 tacaatgctt tcggcccatt cgtgtacaag gctgtcgggg tcggcggcat gctgcatcag
    20521 caggtagttg taggtttgtt ccagcaattt ggcgcccggt acgttattgt tctttttcag
    20581 gaaggcttcg aagcgagagg caatgccttt tttttcgggg atgcctgcaa ttccctcggg
    20641 caaatccatg atgcggcggc actcttccag gccgaagctt cccaacagga agaaggcttc
    20701 gcgtggagcg gttgcaatcc agttggggtt gccgcgccct gcgttcagca tggtacgggc
    20761 ggttttcttc agactctcgt ctgccatgtc tatcaggcgg ttcttcagtt cgaaaggact
    20821 gatagattcc attttctttt ctaaaagttt tgtatccata agctcaagtt taggttcgtt
    20881 atttattgtt ttcagtcatt cggtgaataa tctctgttca tgtggcggac tatttctttc
    20941 cttgcttgaa attaatcgtc cgatatatgt ttccttttcg tccgacagtt gttgaatcat
    21001 cgtccgacaa ctgttgaatt atcgtccgac agctgtcgga cgaatagcta ttagtgaatg
    21061 ggtatatagt cgcttgcatt tccggcaata attctttgaa tgctccggat tagtaagcat
    21121 tggtacagaa tcgtcttata ttagcaaaac gatgactaca ccccatatta ttaataaggt
    21181 attgcccacg gcataggtca cggtgtatcc cagagcaggt gtctcactct caacggcatc
    21241 ctgcactgcg cctaaagcgg ccgtagtggt acgtgcccct gcgcagacgc ccaaagccag
    21301 tgccggatgg aacttgaaaa cataccttgc cagcagcaag ccgataatca gcggcagggt
    21361 ggtggctgct gctcccacca gaaacaggct gatacctacg tcgtggaagc cctgcacgaa
    21421 actgggacct gccgaaatgc ccactaccgc gatgaacatg ttcagaccga cattgttcaa
    21481 cacccattgt gaaggttcgg gaatgcgccc gaaggtgggg tgcttactgc ggagccagcc
    21541 gaagaacaag cccgcaatca atgcgccgcc gcttgtgctc aagctgatgg ggataccgcc
    21601 gatatggacg gaaagtgctc cgaacaaacc tccgacaagg atacccaggc ctacgaatat
    21661 catatccgtc tggttggtag gacggtctat ataccccaga cgtttggctg ctgcttccac
    21721 ttcctgcctg gtacctacca cttcgatgac gtcgccggca tctactaccg tttgtgccag
    21781 cacgggaatg gatattccgg cgcgcttgat actccggata ctgacaccgt gcatgaactt
    21841 ttcccttcgg ataactgcaa ccgtcttgcc ggcaaccgtc ttgcgtgtga ttgtaaccgg
    21901 taacttttcg gcaggaaaat ccaggagctg ggcatcttgt acttccggcc ctatccagct
    21961 ttcttcgcct atgatgtatt cgcggcgtcc gcttagcact acttcgtctc ccggctctat
    22021 ctgtatgttc atgctgactt ccaccacaac tccggatttg cggaggcgtt ccacaaatag
    22081 acgtttgtcg tgctgccgga agtagacttc caggtcaatc acccgctttc cattcttgaa
    22141 ccactcgttt tcgacccggt aggcacggaa agtgacgggg cgtgccgccg gcatgaatcc
    22201 cggttcgtca gccagagagc tgcccatctt cgcctccagc tccttgcagg cggctttcac
    22261 cttttccagc ccgcccagca tcttgggacc gatggatgat aggacccatg ccgagcctgc
    22321 cgtaccgaaa atgtaggtga cggcgtagga tacgggaatg atgttgacgt aactttgtcg
    22381 ttgggcctcg tccagtccca tattggccat ggtgtcttct gccactccga tgacggcgga
    22441 gatggtttgc gaaccggcca gcagtccggc agcttcaccg gcattgtagc ccatcatcag
    22501 ggccagcagc caggtcacta acagtacgga tatacacatc agtacggcaa agcccacttg
    22561 gggcaatccg tcctttttca gtccgcggaa gaactgggga cccactttat agcccacggc
    22621 aaaaaggaaa agcagaaaaa ataccgactt tatcggaccc ggtacggcta tattcagttg
    22681 ccctaccagt acgcctacaa gcagtacact ggtcactgtg cccagcgtaa acttaccgat
    22741 acgcagtttc cccagccaga atcccaggaa tatagtgagg aaaatggcaa gttcggggcg
    22801 ttccctgagc tggttgaaaa tccattccat aatcaagttg tttaggttat atattggttg
    22861 ttccgatgct ttctggagcg tcgtttcgct atacaacggc ttttaacggg aagtgttttg
    22921 tacaaaagga gttttttaga acatttattc cgtaaaaccg aactttaaga aaaagttttc
    22981 ttccgtacct ttgccatcca aattaggtaa aacaaggtat gaagttgttt tttagggtat
    23041 ttctgcttat ccagctggtt actcttccat tgagagcaca atatatggtg caaggcgttg
    23101 tcaccgattc gttgacgaag gagccgttgc cttatacgtc agtttatctg aaaggaacta
    23161 cggagggagg gatgacggac aataacggcc gtttttcctt caagacctat cgcccggagg
    23221 ccacgctggt catttcggcc gtgggatata atgaatatgt ccggctgatt catcctgcaa
    23281 agtcttctaa gttcaatata gccctttcgc cagccactta tgcactggat gaggtggtgg
    23341 tgaagccgaa gcgtgaacgg tataagaaaa aggataatcc cgcagtggag tttgtacgca
    23401 agatgataga gcatcgggat gactactcgc ccgacgaacg cgacttctgg aaacgtgacc
    23461 gctatgaaaa gatgactttt gctatcaata acttcgacag cttgaagcaa cagaagtggc
    23521 tttaccgtaa gttcaagttc ctgacggatt atgtcgatac ctctgccgtt accggcaggc
    23581 cggtactggc catctccaac cgtgagttgc ttgccacaga ctattaccgc aagtctccgc
    23641 atagccggaa acagtgggtc accgcccgca ggcaggcagg agtggacgag atgctttccc
    23701 agcagggtat ggagcaggct atcagtgtca ccatgaccga tgtagacctt tatgagaaca
    23761 acatcacctt gttcaccaat aagtttgtca gtccgctatc ctcccttggg ccgtctttct
    23821 acaaatatta tctgatggat acgcttaccg ttgccggaaa gccttgtgtt gacttgacat
    23881 ttgtcccttt caactccgag tcgttcggtt ttacgggaca tttatacgtc atgctggaca
    23941 gtacctattt tgtaaagcgt gccgtcatga actttcctca gaaaataaat ctgaactttg
    24001 tggactacat gaagattgaa cagaattttg accgcgcgga ggacggtacg aggcagttgc
    24061 tcaatgagag tatcactacg gagttcaagt tggtggacaa tagtgacggt atttatgcca
    24121 agcgggatgt gtattacaga aattatcagt atgaaccgga tgacaaggct ctgcaggctt
    24181 tccgaaaacc ggaaaaggtg attgaagaga catcggcttc cggctattcg gaagcatatt
    24241 gggatgccaa ccgccaggtg gaggtcagca agaaagagac ttcggtggac aagatgatgg
    24301 cccagttgcg cagctatccc gtttatttct ggacggagaa agtgttgaag gtgctgttca
    24361 cggggtatat tcccgctccg aaggaaaaag aacctttgtt ctatatcggt atgatgaata
    24421 ccactatcag cggaaataca ctggaagggg tgcgcttgcg tgccggcggt atgacgacgg
    24481 catggctcaa tccgcatttg ttcggcaggg gctatatggc atacggtttt cgcgaccatc
    24541 gtgtaaaggg actcgccgaa ctggaatatt cttttcatag gaagaaggaa tatgccaatg
    24601 aatttcctat aca
//
