LOCUS       gnlProkkaDIFPGAIF_61   10600 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIFPGAIF_61.
ACCESSION   gnlProkkaDIFPGAIF_61
VERSION     gnlProkkaDIFPGAIF_61
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 04:04:30
            Original ID  :: gnl|Prokka|DIFPGAIF_61
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 61068
            Orig. end    :: 71668
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10600
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[5000:9308]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9308
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10600
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10600
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(163..1203)
                     /locus_tag="ctg44_58"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
     CDS             complement(1203..1952)
                     /locus_tag="ctg44_59"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             complement(1961..3220)
                     /locus_tag="ctg44_60"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             complement(3174..4658)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_61"
                     /sec_met_domain="Polysacc_synt (E-value: 7.2e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             complement(4861..5004)
                     /locus_tag="ctg44_62"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             complement(5001..6122)
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg44_63_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_63"
                     /sec_met_domain="Aminotran_5 (E-value: 8.1e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        complement(5025..6032)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg44_63_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg44_63_Aminotran_5.1"
                     /locus_tag="ctg44_63"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             complement(6132..7256)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_64"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.7e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             complement(7273..8568)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.2;
                     E-value: 2.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_65"
                     /sec_met_domain="CTP_transf_like (E-value: 1e-12, bitscore:
                     40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 4.6e-118, bitscore:
                     385.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.7e-61, bitscore:
                     199.2, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKS
                     GEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAMMN
                     VAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(8589..9308)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_66"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.5e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(9372..10520)
                     /locus_tag="ctg44_67"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLEFLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(10531..10599)
                     /locus_tag="ctg44_68"
                     /transl_table=11
                     /translation="MYATSFSSLGMMIASIANLIKK"
ORIGIN
        1 gatcataaaa cattccgcca tcagtccaaa cgccatcaat atctgtaagt ataagcttta
       61 tctctttcat ttttttagta ttttaccctt atttattaat cactacttag cttatagcag
      121 gcagtactct ataccgtaat acaagttgca gtaggaatat atctattcaa taaaatcagg
      181 atatattatt tcattcgctg atatatcttg tttagcaaaa tgaccaatta catttttttt
      241 atctatccat ttataaccat caccaggact cagtaaatga atgtccgact cttgaataat
      301 actacctgct ggaatatatt ttcgagtggc aatagaacgt tcaagtttta tcttagactt
      361 ctccacccct ttttctatat aaagatcttc agtaccaagc caacactctg ctatgcgaat
      421 atctcgaatc atacgattaa ccccatctgg acctaaagag ccaagctggt ctgttccttt
      481 catatgccga tcaattgtta catgcttttc tataatttcc gctcccatcg ctacagcagc
      541 tgtagcagca gaaataccta ttgtatgatc agaaaaacct atctcaaact tattgtaatg
      601 cttcttcaaa tatgttattg tacgtagatt caaattattt ggatgagttg gatactgaga
      661 tacacaatgt agaatagcta tattactatg atatctcgtt atcacatcta atgcattgtc
      721 aagttctctt tgaccagcca ttcctgtcga taatataata ggaatatgag tttctgctaa
      781 tgcttcaagc aatggtaagt tagtcaaatc acgactagca acttttagcc tatccggtgt
      841 gaacagttta agcaaagaca gacatccttt ggcacataac gtctcgataa aatctaatcc
      901 taatgactta gcatatttat aaatctcaaa atgcgcttga tcatcaagct caagaaaagc
      961 acgatgttca ccataagtac gcccaaaaga attaggattg tcatatattt gattcatttg
     1021 agaaacagcc aattcttctg ataaatctct tttagtcatt ttaacagcat tcattggcat
     1081 gaaatccata ccaaaaacat cctcatgtac aggtcgtgag attaattcaa taatcaactt
     1141 agccaagtca acagaaccat tatgattctg ccctatttca ccaataatat aagtattctt
     1201 cattatttag aatttttttt tatttgttgt ttcatcagtt gaatgtattc tgcatgtctt
     1261 cgaacatagt ctacaatcac ttctatcgat atttccactc ttttttcttg taaatcccta
     1321 tatattctct gtgctacaga aaaatcttct aacgtatcaa tcgtgagtcg aatattatga
     1381 tgttttgaca cgactggaga tcctgaaatc cattgaatat taaaaagttc aggatgacta
     1441 tatatataat tagtaacatg ttcacgatac aataaatcat cagtaaatcc tataactcgc
     1501 ttcagcgcat caagcgttac aaattctccc caaaaaccga aatgagtttt aattgatgga
     1561 gtaccatcaa tatcaaaact tatataatcg ttacaagatt tcattgctat ttcgaccaat
     1621 tgccttgccg catgtacatc taaaaatgga ttatcagaac atattcggaa tataccctgt
     1681 atatcaaaat attcagcaac atcaatgaat cgttttaaaa catcattctc ctcacctctg
     1741 aagcacttta cccctaatgc aagtgccttc ttttcaatag gttcattgat aacagaattt
     1801 gttgtagcaa taattactgg aatattcgat atagcagaaa gcttatgaac cattaagtca
     1861 agaatcgatt gattaccata gaaaggtttc aatatttttc caggcaaacg tgtagaacct
     1921 aaacgtgcct gcaccacaaa tgcataattc attttattta ttatatttca tttaaaaata
     1981 tgtcacatat tctctttgtt gaattatcat cttgaaattg attcatcaat aaagaaatat
     2041 gacgtcgatg ttcagcatga atatctttcc cagccagaag tcccatcaca gcatctatca
     2101 attcattata attgtaaaca atatcacctg cacaaaaaaa ttctattggc tcaaatgaga
     2161 aacctcttac tctacgatat tcttcaatat cgtagaaatt aaatatgact ggcttattta
     2221 ccaataaaaa atcaaaatag gtagaagtat aatcagtaat cattccatct gaaaatgaca
     2281 aaagatcata caatccatat ttatatgttt gttcaaaaac aagtatacct ttgggtaaat
     2341 ctttttttaa gactgtttta ttctgcaaag gatgtaattt aagaattaaa gccgcattaa
     2401 acttcaatag tattttcgat aacttcaaca aatcacaatc aacatatccg agtattgaac
     2461 gcaaattacc ttcagtaaca gtctcataat cacgaaaagt tggagtataa actatatatt
     2521 tagttacatc atatcccgca aatttcgaaa tttctctttt aataacattg caattatttt
     2581 tcgatatcaa caaatcattt ctgggaaatc ctaagacttt gaatttatca tatgagattc
     2641 cacaatctat tgaaattatt ctagcactta aacaagaagt agcaatagag taatcaaatg
     2701 agttacatgt tgtattacga aatttatcat aagaatgatc tcccatatga taatcatctt
     2761 tgaatggagt ataatacccc aaacaaataa tctgttgaga gcgtttttta aatgaaaaat
     2821 cataataaaa agtagctgta aaacatttac ttgctctaca aaaacaaaaa aaggcataca
     2881 acatatcctt aaaagatact ttattaaaga aaaaacgtcc aacacatgca cataaaaaag
     2941 tacacctaat attaggattt atgccataaa tatattcttg atattctgaa atacgagaag
     3001 aatcataaat ttcaacatat attttataat attcagcact atcttttttt agcaaataat
     3061 ttaacagaac gagaacatta tctgacgaat aatttataat atcatattta tctgttctac
     3121 aattaggatg aggaataaaa tacaatgatc tactatcaac tggcacacaa tggttaatta
     3181 tctttactat tacttgaaaa atctttttta atattttcat ctatgttttt agttttaatg
     3241 atcaatgtta aaatacaaaa aaaagaatct agcttaaaaa gaaaagaaag taaaatatag
     3301 aaggacatcc cagtaataca tccaatcaca atttttacta tatcagtttc aaagaaagaa
     3361 atacatataa aaacgatccc ccccattatg aaagagagta ttaaacttgg aaatacatct
     3421 ttaacttgca actttaaggt caaatcaata agagaattag tataatatgt attcaaatat
     3481 gtcgctatca gagagtaaat aactctaccc caacacatca cctcaagccc aaatggaatt
     3541 gacacaaaaa gaatgaatat agcaatcgtc ttttttatta tttcaagacg taacgacaga
     3601 tcagatcttc ctttaaccca taataaattc aaattaattt ggctcaaatg atcaaacatc
     3661 caatccaaac ataatatctg taaaagaata acaaccccag accatttatc tgttaacaat
     3721 agactaataa taggattagc caaaacaagt aaacctacca ttaaaggaaa aattatatat
     3781 gaggataatc tgatataatt tcgatatgcg tttgttaaac atttatcatc atcttgaatg
     3841 gaacttaaaa taggatacgc tactctagaa actaaagcat ttaaattatt ggaaggaaaa
     3901 atagcaaatt gttctgctct tgtatagtaa ccaagctcta caacagaaaa cttttttcct
     3961 attacaatgg tatacagatt acgatatact gtattgataa gacttgagat caataattta
     4021 gatccgaaat tgaataatct ttcaaaagaa cttttggaga aagtatgtaa aggtttccaa
     4081 tgaactaaac agtaaaacaa aattgtcaaa attatactat ttaagagagt ttgccaaact
     4141 aaagcccaaa ccccgcaacc gacataagcc atccatattc caatcacgcc tgatataaaa
     4201 gctgcaccta atgaaatttt agattgagtt ttaaagttta cagaaataat taatttcgtt
     4261 ctgtgaatag ccgataaagc atttattatc aacgacaatg ctataaaacg aattacaaga
     4321 actaaagtcg gcatattata aaagtctgca atcaaagaag ccgaaaaaaa caatatacca
     4381 tagaataata ctgcgacaag aatattaaaa taaaagacag tggcaaaatc ctcttcagtt
     4441 ctatcttttt tctggattaa agcatttgta aaaccgctat ctataaatac ttgagcgact
     4501 tgaagaaaaa tagctaacat cccgatcata ccataatccg atggtagtaa caaacgagct
     4561 aatattattt gaattataaa ctgtactcct tgtaaagaga aacgttctat agcgctccac
     4621 attattcctg atacagtttt ctgctttaga ttttccatta cttaaataca gtataaaaac
     4681 aactacattt accgatatca attatatttt tccaatattc tcactaattg gttattatct
     4741 tcttcgcccc ttaccgcaat tctaatatgg tctctcccac taaaagcaaa ttaccctaca
     4801 caaacattat ctcctataac taccgatgcc tttttataag aataaagaac tcctaatgca
     4861 tcacctcaaa ttaatattgc catatttgcc tactaagcga aagctacgaa taggcactcc
     4921 agaaataaca ctttccggat ggaagtgtat accacgaagg gaaaaataaa aatgacgaat
     4981 cttcaataat atttctgcaa tcatgacatc ggtaatgtga cgttataatg atttaatgca
     5041 gcttttagta ctttaaagaa gttctcaata tcatctactt ctatctctcc taaagcacag
     5101 attctaaaag tatcctcagt tgatatctta cctggataaa tcgtaaatcc acgctcataa
     5161 caataatcat gtattttctc aaaatcccag ttgggatctt ctgggtattg aactgagaca
     5221 accagtcctg actgccattc acgctttatt acacttttaa gaccaatttc atttatacct
     5281 gaatgaatag cctcaaaaac tcttttgtga cgggcaaact tagcttcttc acccacttca
     5341 aaatattcat ttaatgcctg acgagtggcg taaatagttt gtaccggtgg agtaaaatgc
     5401 atttcacctg ttctctcaaa attctcatac tgcaaataaa gattacaata gtaagaacgc
     5461 ttgggatatt tttttgaaaa cttaatctgt tcctcattgc ctataataaa agaaagacct
     5521 gtcatcgctt gaagtccttt ttgagcagat gccatacaaa aatccacatt atctttctct
     5581 atatcaaaag gaatcatgcc caaagaagaa gtagtatcga cgacaaattt agcctgatat
     5641 ttatgagcta tagcgcccat ctcgcgaata gggttcagaa ttcctgtacc cgtctcgtga
     5701 tgagtagtat aaaccatagc tatatcagga ttttcttgca acacattttc caccaccgat
     5761 aaatcaggac gttcgtaaac ggaaaattcc aaattaatat gaggcaaacc ataatattga
     5821 cacacttcta cagcacgggt actatatgcc ccattattca ctataagcac ccttttgtct
     5881 tcaggaagaa gagaatttag acatatatca atattgatgg ttcctgagcc acaaaataat
     5941 acagcggtat gtttttccaa attcccatga gcaactctga ccaaatcgtc ccgaagttgt
     6001 ttcatcatac ctgcgaattc tttctcgcga ggacaaatat ccggaacaac ttgtgccatt
     6061 tttacactgt cagtagtagt ggcaggccca ggatttaata atatttttct ttctattttc
     6121 atcgaatata tttattttaa aaaatccata aaatgctcct tattctctat aggagtagtc
     6181 gtgggacgtc ccaaattctc ccgagaatct attttaacct ttatttccaa caaaacagga
     6241 ccacataact ttggaagctg cttcattgct tcttcaattt caacttttgt acaaacagta
     6301 taagtatgct tatatccgct cccccggaca atagccggaa tatctaaact aaatcctaaa
     6361 gtaggctgtc ctcctacaga ctcgtgagca ccattgttaa acaaaatatg ataatagttt
     6421 ttaggagata aatcgccaat gttactaatt gcccctaaat gcataataaa tgctccatca
     6481 ccatccaagc aataaacagg tctatcttgc tttgctatag caatacccaa agagattgat
     6541 gaactatgtc ccatagagcc taccgtgaga aaatcatgtt catgaccttg ctctttcatt
     6601 tctcgatatt caaataactc acgagaaagc ttgccagtag tagaaacgac cactgaattt
     6661 tcaggcagat aatccacaac tatttgcaaa gcatcctcac gagataaagg ataattacat
     6721 ccgaactctt tttgaagttt atatttgcca aaaacatctt tccgaataat tattgcatga
     6781 ggaatattct tagtttttgc tgattgtatg atatcatgga gctgaataaa tgcatcattc
     6841 tcatttgaat caagaattat ataaggaatc cgcattgctt tcaacaaatc taaagttacc
     6901 tcaccctgtt ttttatgctg aggttcatct tttgttcccg gttcaccacg ccagccaatc
     6961 atcaaaagca ttggaaaact gtatacttgt tcatctgcaa gagacagcag aggattaaca
     7021 gtattaccca agccggaatt ttgcatataa accacaggaa ccttacctga tgccatataa
     7081 taacctgaag caattcctac agccgcacct tcattagcag ctatgatatg tttctcacgt
     7141 gaagtatggt ctgtgatata ggcacaaata ttttttagta atgagtctgg aactcctgta
     7201 aaaaaatcaa cgtcatgact cagaaacgtt tcataaactt tttctacgct taacataatg
     7261 atattcctct ttttatttag tacctggaat cagttccaat atttctttta tgggcataca
     7321 cagttcgcgc acctctaaag cacgttcatt ctctaatatt atctttgcga cattcatcat
     7381 agcaggataa gcggcacgaa gcatatgatt agcataaata attatattca caccccaatc
     7441 acacaattca gactcataaa tatgatcata tgtagtaggc acaaccacga taggtacatg
     7501 agcatactgt tttcgaaacg ccaaacaaaa ttcttttata tcttcacccg acttgctatg
     7561 tatcataata ccgtccgctc ccgcttggac atatgcaaaa gctctctcta aagcatcact
     7621 taccggcttt cccgctataa ggctctcaat acgagcgata atcataaaat catcagtaat
     7681 ctgagatgcc tttcctgctt tgatcttatt acagaaacct tcgattgtat cttgagtttg
     7741 aataacatct gtaccaaaca atgaattctt ttttaatcca actttatctt caattattat
     7801 agctgaaatt ccatgacgtt ctaaagtgcg tactgtaaat acgaaatgtt caattttacc
     7861 acctgtatct ccatcaaaaa taataggttt agtagtacac tccagaatat tattcaaatc
     7921 ttgcaatcgg gtagttaaat caaccgcctc aatatcaggt ttacctttac tggttgaatc
     7981 cgtaaggcta ctagaccaca ttccgtcaaa tacttccctc ttatcccctt ttaatatttc
     8041 ctgattttca attatcaagc cacatagtcc atcatgagct tccaaaatac gaactacggg
     8101 tttggcattt atcaaacgac gaagtgattt taaacgtaca tcaggggttg tacctatagc
     8161 cttaatatct ttatccaaag aagatgaatt aattcccaaa gtatatggaa tttcgataac
     8221 ctttcctccc tgttcattca tcacttcaaa tacgcgcaca cgttcttcac gtaaaggccc
     8281 ggttttccag tcgtcaccat gaattatata gtcaggttta atgcgtttga gattctcaac
     8341 atagctccat tcttcttgag gaacaacttt acatacgcct ttaatattct gaactacctc
     8401 ttttcgttgt tcataggtca gataaggaag gcgtttatgc tccgcaatag ctttatctgt
     8461 aagaagacca attataacat caccgtattt agtagcctca ttaataatgc ggataagtcc
     8521 tggatgcata atatccgcag tcatcccaat ataaactgtc ttactcataa tttgatatat
     8581 tattttaatt aacaatacgg aacaatatat ttctctgcat attccaaatc tgatatgtca
     8641 tcgatttcat accatttcag cccttctact ttatgcacat aaacaggaga ttgagaacaa
     8701 gatattcgta gtaattcata ctcatatccc aaattgggtt gttcatcaac aatactcgca
     8761 taatcagcac acattatttt gtaaaaggaa ccggatagtt tatggatgcc gaccaattcg
     8821 cctttagcgt ttagtttatt cttattgaca gaacatgaag aaaggcgaaa attatcatca
     8881 tgttccacat aatactgatc ttgaaacttt gtcactggag ttattagcat tgcatctgcc
     8941 gcaggacact ccaataagct cattattgct tgtttctcaa aaatcaaatc tgactctaac
     9001 aataaaaaat catcattgcc cagaatctcc cgcgtattat ataaagtata catactattt
     9061 gtttcagcat aacgaggact aaaacaggtt tcaagcatag gatagtctgt cttcaattct
     9121 tcataaactt cttgtttata tcctgtaccg attacaattc gctcaatgtc acatgataac
     9181 aaagtatcaa tagaacgaac tatcattgga atacctccca ctttgacgaa ccctttaggt
     9241 atcaattctg tatattggcc aaaacgggtt cccatgcccg cagccattat catagctgta
     9301 cgtatcattc gtttaataat atagtaagtg aatttaattg atgtaagaat gttgtaaacg
     9361 acgttttagc atcatttatc ctgttctatc tccttatttt tcagttcttt tctcaagcta
     9421 gccagcagac ttttgccaaa aaacacccac acgagagtac cagatacgga caggaacaca
     9481 aataataaaa tataaatttt gagtcccata cctgaaggtt tcaaaggtac aacggcaggc
     9541 tcaactactg caaagactgg cttttcctcc tgtactttgg ctctggatac ctgcaactga
     9601 ttagcaacct gactatatat ctgataagcc aaactcatgt cgttctgtaa acgctcctgc
     9661 tcagcacgta cactttgaag aaccacatta tcatgggcgt ctacataatc cgcatatttt
     9721 ctttgagcag cataatattc ctgctgacgt tctttaaaca accgttccaa atacgcacag
     9781 tcttctttta cttttgaagt tcgataccca ataatatatt cctgtaattt atgaacgaca
     9841 gaatctgcta taaccgcagt gatctgcgga ttttgtaagg tgaccgtaat gctcgttatg
     9901 gcggttttct tatcaatgga tgcactaatc ttctttttaa gaaaattaat cttctcattt
     9961 acttctttcg tcaattcgat agttccttgc cgccctccac tggcaggaac cgtatcttct
    10021 ccgaataatg atttaactcc tcctattact atgcccggaa aacctataag ataatcccac
    10081 caaggagatg actcttcatc gagataagac cccaaagtca ttttatcatc ctttttagaa
    10141 acggagactt ccatttctaa aaattccaat aaaaaaggag ttgaagaaac aatatctgct
    10201 gaaagagaag cgttcaaggc atctgtgctt tcccctatta gagccccatc tcccaaaaac
    10261 gaggcagcaa gtccggctaa accattactt cccttcgcat tacccatttc aggagaaagg
    10321 gtaaccttta ctgtatattg cttgggaatg ctcaatgcca ccactatagc aattattact
    10381 cccactccag cagctttgca tagtactcca cgaacagtaa taatcttata aaaaatagcc
    10441 atcaagtcta tttccatttc atcatctttc cttttatcca cttcagaaaa cggttcttga
    10501 taagattgct tttcaatcat aataggtcat ttatttcttt atcaaattag caatagaagc
    10561 aatcatcatt cccaaagaac tgaaggaagt agcataacct
//
