LOCUS       c00080_gnlPro..        17039 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIFPGAIF_108.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:20:06
            Original ID  :: gnl|Prokka|DIFPGAIF_108
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17039
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17039
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3564:7039]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3565..7039
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17039
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17039
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(565..825)
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="MAAHQEGLVAVLLFHPSDGFLGDEVGGEAEHPFAELVVAGPRVGA
                     LYESRVTVFALIVEDGVVVESLRLRLDMPFADESGVVSVGL"
     CDS             1252..1779
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="MFYEESARMPFVIRYPKKVPAGKRLDDLILNVDFAPTLAEFAGVK
                     MENVQGDSFVSNLEGNTPTDWRKEIYYRYWTNHAIRPAHFAIRSDRYKLIFYYARNLDM
                     TDTENFDFTPSWDFYDLQNDPHENHNAYNDPKYAPVIKQMKKDLLRLRKETGDTDEKYP
                     EMQKLLEKYYNK"
     CDS             2587..3405
                     /locus_tag="ctg80_3"
                     /transl_table=11
                     /translation="MESTLIHRNLLRGQHIPKDKCTQNCMLFMIEGELLINSDEHPGTT
                     LHEKQFILQAIGSKYEILALTDVSYILFWFNELPLLCENRYREIIDQAEGPLTYTPMVM
                     NPRLFYLINDVAAYLDESTPACGKYIDLKCQEMVYMITNYYPLPQLRAFFYPISTYTES
                     FQYFVMQNYSKAKNVEEFAHLGGYNTTTFRRLFRNLYGVPVYEWMLEKKREGILEDLQH
                     SNMRITEICNRYGFDSLSHLAHFCKDSFGDTPRALRKKAANGEKIGKITD"
     CDS             3565..4230
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.8e-131, bitscore:
                     425.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVTGIALVLFLTFHMAMNLVAIISADGYNMICEFLGANWYALVA
                     TAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQNMLVLGIIVIVGLG
                     LHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPVYVVLYLIWLFALW
                     FHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVVFFVKSLLCGGAC"
     CDS             4268..6247
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.2e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.1e-37,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             6284..7039
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.2e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 8.9e-26, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.5e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             7200..8429
                     /locus_tag="ctg80_7"
                     /transl_table=11
                     /translation="MNKLLLIWIVVLLTSCITNQENARDTLFVNLTDATDSQSLKLSDF
                     GNTVRYVPLETNEVCLIGNNPHIALLEDKIVIATKDQCFLFHKQTGKYICSIGHIGDDP
                     SGYSSTNYWIDDAGLFYFFRAPDQLLKYNQKGEMTGKIQIPHIPAAPDFFAFSDSTIIA
                     HCNSSIGLESSNSLLFLNSFGEKLDSIPNLLKSPSIPSPDNISSLSIIKRGAGFFGNLG
                     RRGVMIIKDKEQGELLLPLYNPSLWSSENEVRFRETFTDTIYTIKNRKLYPYMVFHTDT
                     DHSSANPLWYSNPQSIYVAYVLENTHSVFFQYVKNKQVYNGLYNKETQQTKFAKCQQFI
                     VDDLTSEQELKVDLSALCSYKGEYGFILEAASIPDASQKQSDNKNENIPHWMSQLDEDA
                     NPVIAIVSDK"
     CDS             complement(8501..9742)
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="MTGQNATRHGVTNWINAESNNRNPFGPPQWNWKGLRKDMPTMPRV
                     LQQAGYKTIHVGKAHFGCMGSEGENPLNIGFDVNIAGSGIGHPGSYYGEWGYGHIKGQK
                     IRAVPDLEKYHGTDTFLSEALTIEANREITKAVEEKRPFYLNMAHYAVHSPFQADKRFL
                     SRYTDPDKNEQARAFATLIEGMDKSLGDIMDQLEKLGIAENTLILFLGDNGGDAPLGDE
                     RGYGSSAPLRGKKGTEFEGGMRVPFIAAWAKPEKKSKVQKNLPIEVGSMQTQLGTIMDI
                     YPTVLSVAGCEVPQNYVIDGFDLKKQLSGKVDKKRPESFLMHFPHAHRGSYFTTYRMGD
                     WKLIYYYLPETPKQPKALLYNLKDDPEERNELSAAHPDQCREMIREMSARLEKEGALYP
                     VDKQGNELKPFVYF"
     CDS             9854..10096
                     /locus_tag="ctg80_9"
                     /transl_table=11
                     /translation="MTHRLTTLICDKRNRRIHKSHVIYKEDNNIRAFLSHPANGRCQTT
                     QYTKFLKSSFCSHYIVFMIYILVIVRVAIDLNLLK"
     CDS             complement(10262..11104)
                     /locus_tag="ctg80_10"
                     /transl_table=11
                     /translation="MSSICQGTWDCQNCPKAVDNAIAHVIHPRGYHQPVRKCEENFILF
                     LIRGEVLVNSQEYAGTMLRAGEFILQAIGSKFEMLAMTECECIYYRFIQPELFCDFRFN
                     HIMKEVSSPLIYSPLKIIPELKYFLDGSKSYLSESKVCRDLLSLKRKELAFVLGYYYSD
                     YDLASLVHPLSKYTSTFQYFILQNYKKVKTVEELAQLGGYTVSTLRRIFNNVFHEPVYE
                     WMQARRKEGILDELLNTNNSISEICYKYGFESLPHFSNFCKKFFGASPRMLRTNKKTI"
     CDS             complement(11303..12082)
                     /locus_tag="ctg80_11"
                     /transl_table=11
                     /translation="MSTTAVLPSSAWIANKATYASTWSVAGGPYYWPLDENLQFFAYSP
                     SDGVTYTGPDGTIAGYPKFTYKVGDTAADQKDLVISSVLNQTKETDKTAPVVSLNFKHA
                     LTQINVQVIKGSTDYTYEFAADNAVTISGIKGEGTFAYTGADTGDWTPEGTEATYTYTL
                     GDFTDGTSAIVPGNALMLIPQDITDAKITIRYNTKKGDSYIFKGSKEIPLKSTTAWAFG
                     TKILYKLTLPVGGEEVKIEATAAKWDTEKPETTEPSV"
     CDS             complement(12328..13290)
                     /locus_tag="ctg80_12"
                     /transl_table=11
                     /translation="MQDTRYILLVLLSSLLMLTGCSRRELLDDYPVSGVDIKLDWNGVT
                     DKLPEGVRVIFYPKSAEGRKIDTYLSVRGGKVKVPPGRYSVVAYNYDTETVQIRGEEAY
                     ETIEAFTGYCNGLGIAGTEKMVWGPDPLYVVQIDDLHIANSEEELLLDWKPKLVVKTYF
                     FKIKVEGLEYVSSIVGSVEGMAGCYCLGRCCGMMCDAPIYFEAQGRSGEVTGSFTAFGM
                     PEAAISRAGDKIKLTLAFIKVDKTVQKAEIDITEVVTNSESGGSGGGNVDEPPTEIELP
                     LDEKVKVEKPTTNPDGGGGGIGGDVGDWGDEDEVVLPVE"
     CDS             complement(13298..14575)
                     /locus_tag="ctg80_13"
                     /transl_table=11
                     /translation="MKHGIYTCVILMAFLALSESVYAVVPVFTIASDTIRRVVIYFDQE
                     ETDVDSCYKTNNQEINVLDSLLEERINSRYITALNVVTFVSPDGDSVYNAALSVRRNNS
                     MREFLRQRYPYVDVEKIKLTSEGEDWSELRKLVASDSDLPDREEVLMLIDYHRDNIVKR
                     KELLQKLNQGMAYRYIVRNVLPKLRRAEITVVRKVPEMEKNIFEPVSSVSGLFVSKQEE
                     ALPSDQPDKPEGESKESMAYEVVVSEAEGPVESKTVLAVKNNLLYDLALAPNLEVEIPV
                     GKRWSLNAEYKCPWWLNSKHDFCYQLLSGGVEGRCWLGNRQKRNRLTGHFVGLYAEGGI
                     YDFQWKGDGYRGDYYGAAGVTYGYARQLARHLSLEFSFGIGYLTTEYKKYTPYEGDIVW
                     TTSGRYNFIGPTKAKVSLVWLIKRGR"
     CDS             complement(14847..15344)
                     /locus_tag="ctg80_14"
                     /transl_table=11
                     /translation="MALEYVVTKRVFGFDKDKNEKYVAKSVRSGRVSFSKMCGKVSRLC
                     GVHRKVVDLVVSGLVDMMAEDIDDGKSVQMGEFGIFSPTIRAKSADDEKEVSSKSIVQR
                     KILFYPGKIFKTTLDDMSITRRAELDTDYTDGSSNNGSGSVKPNPGGDGGKGDEEAPDP
                     TV"
ORIGIN
        1 ctgaggtctt tttcaaaaat atttcgtaat gttgcactcg ctggttgact ctgcctaccg
       61 gaatcaatta cattaaatcg caaaagtttt ccggattata atacaaagtg aataacaatc
      121 actatcttta ggcataaaat cagttcatat gatcatttat ctacatgaaa gcaaccgtct
      181 aacttagact gacttttgaa gaaatgcaac atctatacgt atatgaataa actcgtactt
      241 accggtctgc tggcagccgg aaccatgacg cacctgcaag gcgctcaacc tgccggacaa
      301 cgccccaaca tcctttttat cctgagtgac gaccacacct cccaagcctg gggcatctat
      361 ggcggagtac tggcagaata tgcccacaac gccaacatcc gccggctggc aaaagaaggg
      421 gtagtgctcg acaactgttt ctgcaccaac tctatctcag cacccagccg tgccagtatc
      481 ctcaccggtc tatacagtca ccggaacaga ctgtacaccc ttgcggactc actggacacc
      541 tccatcccca cccttgccac cctgctacaa gccaacggat accacaccgg actcgtcggc
      601 aaatggcata tccagtcgca accgcaagga ttcgactact actccatctt ctacgatcaa
      661 ggcgaatacc gtgacccgac tttcatagag agcaccgacc cgtggcccgg caaccaccag
      721 ttcggcgaac gggtgctcgg cttctccacc gacctcgtca ccgagaaagc catccgatgg
      781 atgaaagagc aggacggcaa ccaacccttc ctgatgtgct gccatttcaa agcaacgcac
      841 gaaccctacg actacccgat acgcatggag catctctacg acggcgtcac cttccccgaa
      901 cccgaaaacc tgctggactg gggaccggaa accaacggcc gttctttcaa aggacagaca
      961 ctggaagagc tggaacgccg ctggcgcatc gcatcacagg accccgacaa gtggtggtgt
     1021 cgctaccccg gactgccgtt cagcaccgaa gggatgcaac ggacggccgc cagacgtgct
     1081 tcctaccaaa agtttatccg tgactacctc cgttgcggcg ctaccgtcga cgacaacatc
     1141 ggcaaactcc taaacgctct ggacgaaatg aatatcgccg acaataccat cgtcatctac
     1201 gtctccgacc aaggctattt cctaggcgaa cacggcttct tcgacaaacg gatgttttat
     1261 gaagaatcgg ctcgtatgcc tttcgttatc cgttatccga agaaggtacc cgcaggaaaa
     1321 cgtctggacg atctgatact gaatgtcgat ttcgcaccga cgctggcaga atttgccgga
     1381 gtaaagatgg agaatgtgca aggagacagc ttcgtcagca acctggaagg caacacgccg
     1441 accgactggc gaaaagaaat ctactatcgc tactggacca atcatgctat tcgtcccgcg
     1501 cacttcgcca tccggtcaga ccgttacaag ctgatcttct attatgcccg aaatctagac
     1561 atgactgata cggagaactt tgactttact ccgtcatggg acttctatga cttacagaat
     1621 gatccgcacg agaatcataa tgcatacaac gatccgaaat atgcacctgt catcaaacag
     1681 atgaagaaag acttattgag acttcgcaaa gaaaccggag atacggacga gaaatatccg
     1741 gaaatgcaga aactgcttga aaaatactat aataagtaag tgactggtac ggaaactgaa
     1801 ctgtcgcatt tataacttga acttaggcag ctgctacaag tgaaaaagat agcagttttg
     1861 ccctaacgct ctcattattc gcgtgtatcc ctttattcat cggcatttca agcattacag
     1921 caagtatggt ggcagagtga gagcaaaggt ttgctctcac tctgccacca cggcatatag
     1981 gtcgtttatc ctacattata ctttgattta ctgggtatta acatctgacg cgtcagctat
     2041 taacgattgt catgtcagct attaataatt gagaaatcag gtattaacag ctgagaagtc
     2101 atccattatt gactgaaaaa tgaaataata cctttcgaac ggacaggtca atcagagcaa
     2161 cttatgcggt caagtgagtt gaatcgagct gtcatatgaa cgaaatcgac agttgttcca
     2221 agaagtttca ttacttgaaa cagtttgttt catgccttga aacacttggt ttcaacaggt
     2281 ggaactaatg atgaaactac ttgttctgaa tatatcatgt aaagggatga agaaaatgct
     2341 gcagatggca gataaaaatg tattaaagaa cgccattcag gagtccgtga aacttcaaag
     2401 ttgtgcaaac aaaaccaata aagacaatca tatccccgtt tctgctaaaa cataatggaa
     2461 gaaagaattt tattttcaca aaaaacgact atctttgtcc ctgtagacaa cgattcacgg
     2521 ataaaaccca tgtcaaaaga ctcactttgt gctcaacata cagattgctc aggatgcccc
     2581 aaagcgatgg aaagtactct tattcacaga aatctgctca gagggcagca tattccgaag
     2641 gataagtgca cgcaaaactg catgctcttt atgatcgagg gcgaattgct gatcaacagt
     2701 gacgaacatc ccggaacgac actacacgag aaacagttta tcctgcaagc catcggctca
     2761 aaatacgaga tactggcact gacggacgta tcatacatcc ttttctggtt caacgaactg
     2821 ccgttgctat gcgaaaaccg ctaccgtgaa atcatcgacc aggcagaagg cccgctgacc
     2881 tacaccccaa tggtgatgaa cccgcgcctg ttctatctca tcaacgacgt agccgcatac
     2941 cttgacgaat cgacacccgc ctgcggcaaa tatatcgacc tgaaatgtca ggagatggtg
     3001 tatatgatca ccaattacta tcccctgccc cagttgaggg ctttcttcta cccgatcagc
     3061 acctatacgg aaagtttcca atactttgtc atgcagaatt acagcaaagc gaagaacgtc
     3121 gaagaattcg cacatctggg aggctataac accaccacct tccgccgtct cttccgaaac
     3181 ttatacggcg tgcccgtcta cgaatggatg ctggagaaaa aacgggaagg catcctcgaa
     3241 gacctacagc actctaatat gcggattaca gagatttgca accggtatgg tttcgactcg
     3301 ctgtcccacc ttgcacactt ctgcaaagac tccttcggag acaccccgcg cgccttgcgc
     3361 aagaaagcgg ccaatggcga aaaaatcgga aagatcaccg attaaggaat tatttcttta
     3421 attctttggt caatcaatct atttccccta tttttgcagt ctgtaagagg tgtaaaacgt
     3481 cgaaatttta gttctaacaa ttaaataatt taaattcaat catttatgtg gttaagtaat
     3541 tcatctgtag gaaggaaagt ggtgatgagc gttaccggta tcgcccttgt cctgtttcta
     3601 acatttcaca tggcgatgaa cttagttgca atcatctcgg ctgatggtta caacatgatt
     3661 tgtgagtttt tgggagcaaa ctggtatgcg ctggtagcta ccgcagcact ggctgctctt
     3721 ttcattattc acatcatcta cgcgttctgg ctgacaatgc agaatcgcac agcgcgcggt
     3781 agcgaacgct atgcagtagt cgacaaaccg aaaactgtag agtgggcttc tcaaaacatg
     3841 ttggtgttag gcattatcgt tatcgtaggc ctcggtttgc acctcttcaa cttctgggca
     3901 aaaatgcagt tgccggaact gatgcacaac ctggacatgc acgctgatac actgacgctg
     3961 gcttatgcgg caaacggtgc atatcacatc cagcagacat tctcttgtcc ggtttatgta
     4021 gtgctctacc tcatttggct gtttgctctg tggttccacc tgactcacgg tttctggagc
     4081 tccatgcaat cactgggatg gaacaacaag gtatggatca atcgttggaa atgtatttct
     4141 aacatctatt ctacgattgt agtactcggt ttcgcactcg tagtagtggt attcttcgtg
     4201 aaatcactcc tttgtggcgg tgcttgctaa atagtaaatt gtaaatgatt aaattgtaaa
     4261 taatattatg atcaagatag attcaaaaat tccagaaggc ccggtggctg agaaatggac
     4321 caactataaa gctcaccaga aattggtgaa ccccgctaat aaacgccgtt tggatatcat
     4381 cgttgtgggt acgggtctgg caggtgcttc tgctgctgca tccctcggtg aaatgggttt
     4441 cagagtattc aacttctgta ttcaggactc tccgcgccgt gcacactcta tcgctgcaca
     4501 gggtggtatc aatgctgcaa agaattatca gaatgatggt gactccgttt accgtctgtt
     4561 ttacgataca gtaaaaggtg gtgactatcg tgcacgtgaa gccaacgttt accgtctggc
     4621 cgaagtatcc aacgctatca tcgaccaatg cgtagcccag ggtgttcctt ttgcacgcga
     4681 atacggcggt acactggaca accgttcttt cggtggtgca caggtatcac gtacgttcta
     4741 cgctaaaggc cagaccggtc agcagctgtt gctgggtgct tactccgcac taagccgtca
     4801 ggtaaacgta ggtacggtga agttgttcac ccgttatgaa atgcaggacg ttgtaatcat
     4861 cgacggacgt gctcgcggta tcattgccaa gaacttaatc accggcgaac tggaacgttt
     4921 cgctgctcac gccgtagtaa tcgctaccgg tggttacggt aacgcttact tcctgtctac
     4981 caacgctatg ggttgtaact gtacagctgc tatctcttgc taccgcaagg gtgctgtatt
     5041 cgctaacccc gcatacgttc agattcaccc gacttgtatc ccggtacacg gtgacaagca
     5101 gtccaaactg actctgatgt ccgaatctct gcgtaacgac ggtcgtatct gggttccgaa
     5161 gaagaaagaa gacgctatca aattgcagaa aggcgaaatc aagggaagcg atattcctga
     5221 agaagaccgc gactactacc tggaacgccg ttatccggca ttcggtaacc tggttccgcg
     5281 tgacgttgcc agccgtgcag ctaaagaacg ttgcgacgca ggtttcggtg tgaacaacac
     5341 aggtctggcc gtattcctcg atttctctga agctatcaac cgcctgggca tcgatgtagt
     5401 gcttcagcgt tatggtaacc tcttcgacat gtatgaagaa atcactgacg ttaatccggg
     5461 cgaactggca aaagaaatca gtggtgtgaa atattataat ccgatgatga tttatccggc
     5521 tatccactac acaatgggtg gtatctgggt agactacgaa ctgcagacta ccatcaaggg
     5581 tctgttcgct atcggtgaat gtaacttctc cgaccacggt gcaaaccgcc tcggtgcttc
     5641 cgcattgatg caaggtctgg ccgacggtta cttcgtattg ccttacacta tccagaacta
     5701 tctggcagat cagattactg ttcctcgttt ctctaccgac cttccggaat ttgccgaagc
     5761 agaaaaggca gttcaggcta agatcgacaa gttcatgagc atccagggta aagaatcagt
     5821 tgattctatc cacaagaaac tgggtcacat catgtgggaa tacgtaggta tgggacgtac
     5881 ggcagaaggc ctgaagaaag gtatcgccga actgaaagca gtccgcaagg aattcgaaac
     5941 caatctgttt atccccggtt ctaaggaagg tatgaacgtt gagctcgaca aggctatccg
     6001 tctgtatgac ttcatcacta tgggcgagct cgttgcttac gacgcattga accgtaacga
     6061 aagttgtggt ggtcacttcc gtgaagaata ccagactgaa gaaggagaag caaaacgtga
     6121 tgacgaaaac ttcttctacg tagcttgctg ggaatatcag ggtgacgatg aaaaggctcc
     6181 tgtattgatc aaagaaccgc tggtatacga agctatcaag gttcagaccc gtaactacaa
     6241 gagctaatcg gtgaagttaa acatttaaaa gaattagacg aaaatggata aaaatatatc
     6301 atttacactg aaggtatggc gtcaagcagg cccgaaggct aaaggcgctt ttgaaaccta
     6361 ccaaatgaaa gatatccccg gtgatacttc cttcctcgaa atgctggata ttctgaacga
     6421 acagctgatc agcgaaagaa aagaaccggt tgtattcgac cacgactgcc gcgaaggtat
     6481 ctgcggtatg tgttctcttt acatcaacgg acatccgcac ggtcctgcaa caggtgctac
     6541 tacttgccag atttacatgc gtcgtttcaa cgatggtgac accatcactg ttgagccttg
     6601 gcgttcggcc ggtttccctg tcatcaagga cttgatggta gaccgtactg cttatgacaa
     6661 gatcatgcag gccggtggtt acgtaagcgt tcgtacaggt gctccgcagg atgccaacgc
     6721 tatcctgatc ccgaagccca tcgctgacga agctatggat gccgcttctt gtatcggttg
     6781 cggtgcttgt gtagctgctt gtaagaatgg ttctgccatg ttgttcgttt cggcaaaggt
     6841 cagccagttg aacttgcttc cgcaaggtaa accggaagct ctacgccgtg cgaaagctat
     6901 gttgtccaag atggacgaac tcggattcgg taactgtacc aacacccgcg cttgcgaggc
     6961 tgaatgtccg aagaacatct ctatcagcaa catcgcccgc ctgaaccgcg acttcatcat
     7021 cgctaaactg aaagactaag cgtgagcttg atttgattaa tagcataaat cccccgtcgg
     7081 cgttagctgg cgggggattt ctttttactg accaattatt tatagatagc ttgttcatta
     7141 tccgtttttt attcttttct ttgtgacata aggccagaca atcaaataaa ttaaatacga
     7201 tgaataaatt attgctgata tggatagtag tcttactaac ctcatgcatc acaaatcagg
     7261 agaatgccag ggatacatta tttgtaaatc ttacggatgc aactgattcc caaagcctaa
     7321 agttatctga cttcggaaat actgtacgtt atgtaccttt ggaaaccaac gaagtatgcc
     7381 tgataggaaa caatccccat atagcgctgc tggaagacaa gattgtgatt gctactaaag
     7441 accaatgttt cttattccac aaacagaccg ggaagtatat atgcagtata ggccatatcg
     7501 gtgatgatcc aagtggatat agctcgacaa attactggat agatgatgca ggtctttttt
     7561 acttctttcg cgcaccggac cagttgctaa aatataatca gaaaggagaa atgaccggga
     7621 aaattcaaat tccacatata cctgccgcac ccgacttttt cgcgttttcc gactctacca
     7681 ttattgccca ttgtaatagt agtataggat tggaatccag caactctttg cttttcctca
     7741 actcctttgg agaaaagctg gattcaattc ccaatttatt aaaatcgccc tctatccctt
     7801 ctccggataa tatatccagc ctttctatca taaaaagagg agcaggtttc tttggaaatc
     7861 tgggaagaag aggggtaatg attatcaaag ataaggagca aggagaatta ctgctgcctc
     7921 tctataatcc cagcctatgg tcgtccgaga atgaagtacg tttcagagaa accttcacag
     7981 acacgatata cacaattaaa aacaggaaac tatatccata tatggttttt catacagata
     8041 cagatcattc atccgccaat cctttatggt atagtaatcc gcaaagtatc tacgtagctt
     8101 atgtattgga aaacacacat tctgtatttt ttcaatacgt aaaaaacaaa caagtctata
     8161 atggtttgta taataaagaa acacagcaaa ctaagtttgc aaagtgccag caattcattg
     8221 ttgacgatct cacttcagag caggaactga aagttgacct gtcggcattg tgcagttata
     8281 aaggagaata tggatttatt ctggaagctg ccagtattcc tgatgcttct caaaaacaat
     8341 ctgacaataa aaatgagaat attccccatt ggatgagcca attggatgag gatgccaatc
     8401 cggtcatagc aattgtatct gacaaatgat atataattct gtctgttttg cctaatagat
     8461 atgctttggc aaaacagaca gttgaaatag tagcacctat ttaaaagtaa acaaaaggct
     8521 tcaactcatt tccttgttta tccaccggat aaagagctcc ttccttttct agccgggcgg
     8581 acatttcccg aatcatctct ctgcattgat ccggatgtgc ggcagacagc tcattccttt
     8641 cttccggatc gtctttcaga ttgtaaagca aggctttggg ttgtttcgga gtctcgggaa
     8701 gataataata aatcagtttc cagtcgccca tgcgataggt ggtgaagtag ctgccgcggt
     8761 gtgcgtgagg gaagtgcatc aggaaagact cgggacgctt cttgtccacc ttaccgctca
     8821 gttgcttttt cagatcgaat ccgtctatca cgtagttttg gggaacttcg catcctgcca
     8881 cagacagaac agtcggatag atatccatga ttgtgcccaa ctgtgtctgc atacttccta
     8941 cttcaatagg caagttcttc tgtactttgc tcttcttctc aggcttggcc caagctgcga
     9001 tgaaaggaac acgcatacca ccttcaaact ccgtcccctt tttacctctc agcggagcgg
     9061 aagaaccata gccacgttca tctcccaatg gagcatcacc accgttatct cctaaaaaga
     9121 gaatcagcgt attttcggca attcccagct tttcgagttg gtccatgatg tcgcctaatg
     9181 atttatccat gccttctatc aatgtagcaa aagctcttgc ctgctcgttc ttatccgggt
     9241 cggtgtagcg tgacaagaaa cgtttgtctg cctggaaagg tgaatgaact gcgtaatggg
     9301 ccatattcag atagaaaggt cgtttttctt ctacggcttt ggtgatctcc cgattcgctt
     9361 ctatagtcag cgcttcactc aggaaggtat ctgtaccgtg atatttctcc aggtcaggaa
     9421 ctgctctaat cttctgtccc ttgatatgcc cgtatcccca ttcgccataa tagctgccgg
     9481 gatgtccaat gccggaacct gcgatattta catcaaagcc gatattcagc ggattctctc
     9541 cttcgcttcc catacagccg aaatgtgctt ttcctacatg aatggtttta tatccggctt
     9601 gttgcaggac tctcggcatg gtaggcatat cttttctgag acctttccag ttccattggg
     9661 gcggtccgaa aggattccgg ttgttgctct cagcattaat ccagttagtg actccatgcc
     9721 tggtcgcatt ctgtccggtc atgatggaag ctctggaagg ggaactcacg ctctgtgcgt
     9781 aaaaagtaga gaaacaaata ccctgtttag ccagtctctc catattcgga gtatgatacc
     9841 agtcattcag cggatgacgc accggctgac cactctcatc tgcgataaaa ggaaccgacg
     9901 tatccataag tcccatgtca tctacaagga agacaataat attcgggcgt tcctgagcca
     9961 ccccgcaaac ggaagatgcc aaaccaccca atacacaaaa ttccttaaaa gctcgttttg
    10021 ttctcattac atagtattta tgatttatat cctagttatt gtacgtgtcg caatagattt
    10081 aaatttactg aaataaaaag tttaatttcc gtatccgcct tgtcatggct ttatttgaag
    10141 tgatccgact ctataataaa gatgtattag actgatttta agggaaacag cagcaatata
    10201 caacaaatgc actatgctca caaagaaaaa aagattattt gacgttctct ctgaaaaatt
    10261 atcagatggt ctttttgttt gttcttagca tgcgtggaga agcaccgaag aatttcttac
    10321 agaaattgga gaagtgtggc agagattcaa agccatattt atagcatatt tcagagatac
    10381 tgttgtttgt attaagcaac tcgtccaaaa taccttcctt acgtcgcgcc tgcatccatt
    10441 cgtataccgg ttcgtggaat acattattga agatacgccg cagggtactg acagtatagc
    10501 cgccaagttg ggcaagttct tccactgttt ttactttctt atagttttga aggatgaagt
    10561 actggaaagt ggaagtgtat ttagagagtg gatgtaccaa gcttgccaaa tcatagtctg
    10621 aataatagta ccccaataca aatgccagtt ccttgcgctt taacgacagc aagtcccgac
    10681 aaactttact ttcactcaaa taggatttag agccatccaa aaaatatttc aattcaggga
    10741 ttatctttaa tggtgaatag attaatggtg aagacacctc cttcataata tgattgaaac
    10801 ggaagtcaca gaatagttcc ggctgaatga aacgataata aatacattcg cactcagtca
    10861 tggcaagcat ctcaaatttt gaaccgatag cctgaagaat aaattcacct gctctcagca
    10921 tcgtacctgc atattcttga ctattaacca atacctcacc tcttatcaaa aaaaggatga
    10981 agttttcctc acatttccgg actggttggt gatagcctct tggatgaata acgtgagcaa
    11041 tagcattgtc tacggctttc gggcagttct gacaatccca agtaccttga cagatagatg
    11101 acatatattt gtgttggtgt ttgatttgtt cctgttggcc aacaaatgta tatgaaatct
    11161 tttatatgac aatgagaaag ggaagaaatt tataaaatca ctctcgttgc aatatgtcgt
    11221 aacgagaatg atcttataaa ttcaaaacta cataaactgg tataaaagac tataacctga
    11281 gaaatattat tctattaata cattaaacgc taggttcggt agtttcaggc ttttcagtat
    11341 cccatttagc agctgtcgct tcgatcttta cttcttcacc accaaccggt aaagtcagct
    11401 tatacaaaat tttagttcca aaagcccatg ctgtggtaga cttcaaagga atctcttttg
    11461 atcctttaaa tatatagcta tcgcccttct ttgtgttata cctaatcgtt attttagcat
    11521 cagtaatatc ttgtggtatc aacatcagtg cattaccagg aacaatggca cttgtcccgt
    11581 cagtaaaatc acctaaagta tatgtatacg tcgcttcagt gccttctggc gtccaatcgc
    11641 cagtgtcagc tcctgtataa gcaaaggttc cttcgccttt aatgccactt attgtaacag
    11701 cattatcagc tgcaaattcg taggtataat ctgtacttcc tttaatcacc tgaacattaa
    11761 tttgagtcaa tgcatgttta aaatttaacg aaacaactgg tgctgtttta tccgtttcct
    11821 tagtctgatt caacacggac gaaataacta agtctttttg atcggcagcc gtatccccta
    11881 ctttataagt aaatttagga tatcccgcaa tagtaccatc aggaccagta tatgtaactc
    11941 catctgacgg agaataagca aaaaactgta aattttcatc taatggccag taatacggac
    12001 ctcctgctac tgaccaagta ctagcataag ttgccttatt agctatccat gctgaagacg
    12061 gaagaaccgc agtagtagac atttctgtcg ttcctgtatt atatgcataa acctggaaac
    12121 cagcattttg taaaccttct gtatcaagtg cagttgctct agttactgct gtactaaaat
    12181 taatttccgc cttttgtccc ggattctcaa actcttcact ctgtgaacaa cctgtaattg
    12241 ttgcaactgc tgcaatagcc aataaaatct ttttcataat tgtatttttt aattcgttaa
    12301 tattgttata tttgtttatg tttaatctca ctcaacaggc agaaccactt catcctcatc
    12361 gccccaatca ccaacatctc caccaatacc accacctccg ccatccggat tagtagtcgg
    12421 cttctcaacc ttaacctttt catcaagtgg caactctatt tccgtgggag gttcatcaac
    12481 atttcctcct ccactacctc cactctcaga attagtaacc acctccgtta tatcaatctc
    12541 cgctttctgc acggttttat ctactttaat aaaagccagt gtcagcttta tcttgtcacc
    12601 tgcccggctt atcgcggcct ccggcattcc aaaagcagta aaactacccg ttacttcacc
    12661 cgaacgccct tgcgcctcaa agtaaatagg agcatcgcac atcatcccgc aacatctgcc
    12721 caaacagtaa caacccgcca taccttccac actgcctaca attgaagaaa catattccag
    12781 tccttccacc ttgatcttga aaaaataggt ctttaccact aatttcggtt tccaatccag
    12841 tagaagctct tcttcactgt tcgctatatg taaatcatcg atctgcacta cgtataaggg
    12901 atcaggtccc cataccattt tctccgttcc cgctattccc agaccattgc aatagcctgt
    12961 aaatgcttca atcgtctcat aggcttcctc tcctctgatc tgcaccgttt cagtgtcgta
    13021 gttgtaagcc actaccgagt aacgccccgg cggcaccttt acttttccac ctcttactga
    13081 aaggtatgta tcaatctttc tgccttccgc actcttcgga taaaaaatca cccgaacccc
    13141 ttccggcaac ttatcggtaa caccgttcca atctaacttt atatctaccc cgcttacggg
    13201 ataatcatcc aatagttcgc gacggctaca tccggtcagc atcagcagcg aggacagaag
    13261 cacaagaagt atgtatcttg tatcttgcat aacgtcctta tctccctctt tttatcagcc
    13321 ataccagaga gactttcgcc ttggtaggac ctataaagtt ataacgtcca ctagttgtcc
    13381 acacgatatc cccctcgtaa ggagtatatt tcttatattc tgttgtcaga tacccgatgc
    13441 cgaagctaaa ttcgagcgac agatggcgag ccagttgccg cgcatacccg taggtcactc
    13501 ccgcagctcc gtaataatcg ccccggtaac cgtcgccctt ccactggaaa tcgtaaattc
    13561 caccttcagc ataaagccca acaaaatgcc ctgtcaaccg gttgcgcttc tgacgattgc
    13621 ccaaccagca acgtccttcc actcctcccg aaagaagctg ataacagaaa tcatgtttac
    13681 tgttcagcca ccacggacat ttgtattcag catttaaaga ccaccttttg cctaccggaa
    13741 tctctacttc cagatttggc gccaacgcca aatcgtacaa cagattattc ttcactgcaa
    13801 gcaccgtttt actttcaacc ggcccttctg cctccgacac taccacctca taagccatac
    13861 tctctttact ttctccctcc ggcttatcag gttgatcgct cggaagcgcc tcttcctgct
    13921 ttgaaacaaa caatccggag acagaagata ccggttcaaa aatattcttt tccatttccg
    13981 gaactttgcg gacaaccgta atctcagcgc gtctcaactt aggtaacacg ttgcggacaa
    14041 tatatcggta agccattccc tgattcaact tctgcaacag ttcttttcgc ttcacgatgt
    14101 tatcccgatg ataatctatc aacatcaaga cttcttcccg gtccggcaag tctgaatccg
    14161 acgccaccaa cttacgaagt tcagaccagt cttctccttc agaagtaagt ttaatctttt
    14221 cgacatcaac atacggataa cgttgcctta agaactctct catcgaattg tttcttcgga
    14281 cagataatgc ggcattgtaa accgaatctc cgtcaggcga tacaaaagtg accacattga
    14341 gcgcagtgat atatcttgaa tttattcttt cctcaagcaa agaatctaaa acattaattt
    14401 cttgattatt agttttataa caggaatcaa catctgtttc ttcctgatcg aaatatatca
    14461 ccacccgcct gatagtgtca ctcgcaatcg tgaaaaccgg aaccactgca tacacacttt
    14521 ctgataaagc aagaaatgcc atgagaataa cgcatgtata gattccgtgt ttcataattg
    14581 ttcgtttctg tgaacaaata tagaagttat aatataaact aaatcatact agcagaacaa
    14641 aaaacaggac atggaaggtt ctgtgaaacg attggaacga atttgcaagt ttagaagcaa
    14701 ataaggagga aacaatagat acaccaaggc attatataaa gaaaaaatgc acagaaaatc
    14761 gagtataacc gattatctgt gcatttgcaa cttttcaata agcctttccc acgctgtctg
    14821 ctacctaaaa agaaagtaca gaagatttat acagtcgggt ccggcgcttc ttcatcaccc
    14881 tttcctccgt ctccaccggg attaggtttt acgctaccgc tgccattgtt actacttccg
    14941 tccgtatagt ccgtatccaa ctccgcacga cgggtaatac tcatatcatc caacgtggtc
    15001 ttgaatattt ttccaggata gaaaaggatc tttctttgga cgattgactt agatgatact
    15061 tccttctcgt catccgcact cttagcgcga atggtagggc tgaagatgcc gaactcaccc
    15121 atctgaacac tctttccgtc gtcaatgtcc tccgccatca tatcgacaag accgctgacg
    15181 accagatcca caactttgcg gtgaactcca caaagacggc tcaccttgcc acacatcttg
    15241 gaaaaactta ctctgccgga acgaaccgac tttgctacat acttttcgtt tttgtccttg
    15301 tcaaaaccga acactctttt tgttactaca tactctaaag ccataattgt taaagtttaa
    15361 atggttaaaa aaataaaggt tatctgtttg ccattccgtt ttgtctgaat gactctgcaa
    15421 agatataaca gggcgcaaac cgtccagtcc cctttagtcc cccttgtgtc tcctttcaat
    15481 ggctttaaag cagtaaatat cctaaagtaa ttcgcttatt ttcaatcgac tatacagatg
    15541 aatatttttt ttccaaagtg cgttcattgc tgtttctcca aatagagtct gtcggtttcc
    15601 agtctccata taccgacata cccccgcccg caatcagtag agaaggagcg cttcgaaata
    15661 caattcttta cctgcttact cagagtctca ctatctccca atggtcaagt aaacatttcc
    15721 aatgtatctt tacctatgac gagatattcc cctctttgat ctgttgcctt aacctgtatg
    15781 cagatgccaa catacaaaaa gataataaat agaaaagtgt gctttctcat agctttataa
    15841 ttttagaaaa ccgaatatac atatatataa tagagcaata atactcattt cggtatttat
    15901 catatgcgaa taaacgaatt attctgtttg ctcaaataga attacgtaca aattagctgc
    15961 attatagtat aaccaacgaa aaagcaacat gatactttgt catacaaaac ggtctatgag
    16021 agaaaggtaa aaatagtcat gcaaatttac caatatacta atccaatgaa tacgatactg
    16081 ccttctcccg atttacccac aatgaaaaac atagacactg tatactaaaa ccgtatttga
    16141 gtttctaata aattctttca tcgtttatta gaaacggttc ccaagtttat taaaaacgcc
    16201 gatacgcctt tcaaatctct ttttcttgaa tttatgcaac aagaaaggct gcaaactccg
    16261 taaaagtttg cagccttttg ctcattgccg ggctacttat gccctaatcc tcataaggat
    16321 ctcctagatg ttttgttatg atcttatact gttttgatgt caaaaaccga tgattgtacg
    16381 gcaagtaacc tgtcggtata agttctttga ccaacgggtt acaaccttta atccatcggc
    16441 tgagacaatg caccgcattt ttactcgttg tacatccggg gaagtacatc gcagccagtg
    16501 cagcaaaaga taagattcct ctcattcgtt tctaagtttt gatttgaatt ttattgttgt
    16561 tattacgact acaaatatac aacataaaaa agcctttgtc aagtcctcaa gaccttcgag
    16621 cgttaataac aaattaaaga actggagtac tggcacataa gcaaggattg catcgtcaat
    16681 gactaacaag tttgttacta acaactttgt tagtaacaaa cttgttagtt aataaaaagg
    16741 ctgagattcc tcaattcaga cccattgtgt gcgataacag tgaaaatccg tgaaagaaat
    16801 caaaagagac gcaaatacaa gaatattatt tggaaggaat agcaagaaga cttacatttg
    16861 tcatgtgatt tttttcatag tattagattt aaggttaaca aaggttggag caaggcgttg
    16921 ctcctttttt tatgccccaa cctttcttta ttttacctca gagatttatt actgtcattc
    16981 cagtactgtc attgactatt ttttcggctt tccacagata taaaccttgc attggtaag
//
