LOCUS       c00018_gnlPro..        24536 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENMPDONF_36.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:15:15
            Original ID  :: gnl|Prokka|ENMPDONF_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 44437
            Orig. end    :: 68973
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24536
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[54437:58973]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14536
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24536
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24536
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             581..1102
                     /locus_tag="ctg18_44"
                     /transl_table=11
                     /translation="MSFLELARKRCSIRKYAPKNVEQEKIDYILEAARLAPSAVNYQPW
                     YFVWVQSAEGKAKLQECYPREWFKQAPYYLIVCGDHQQSWKRGDHKDHMDIDTAIATEH
                     ICLAAAEQGLGTCWVCNFDTELCRKHFKIPETIEPVVLIPFGYPSDPALFDETPKKRKP
                     IEEIIKRESF"
     CDS             1104..1670
                     /locus_tag="ctg18_45"
                     /transl_table=11
                     /translation="MLYIEVLLLAIGLSMDSLAVSVTGGAVLKNNCTAGNIIKIASVLG
                     IFQAGMTVIGYTMGLGFEKYICAFDHWIAFTLLLYLGGKMIYDSTKEEEEDGKFDPLCN
                     RTLCGLGIATSIDALAVGISLAILKSPLLLQASTIGVVTFAISAFGVYFGNRFGKRIDL
                     KLDLIGGLILIGIGTKILIEHVFFS"
     CDS             1715..3439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ILVD_EDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_46"
                     /sec_met_domain="ILVD_EDD (E-value: 1e-183, bitscore:
                     604.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSQQLRKLAPELDSLRLGSGWKIDELSKPQIIVESSYGHSHPGS
                     AHLDKLVDEAGIGIKEKGGRAANYFVTDICDGEAQGHDGMNYSLVSRDIMAAMIEIHVK
                     ATPFDAGVFIASCDKSVPAHLMAIARLDMPAIFMPGGIMKAGPNLLTLEQIGTYSAQYE
                     RKEITEEQFMVYKRDACPDCGACSFMGTASTMQVMAEALGIALPGSALIPAHLPELKET
                     ARKAGEHALGLAKEELKPSDIMTIQAFENAIMVHAAIAGSSNSLLHLPAIAHELGIQLS
                     PDLFDKIHRKIPYLLNIRPSGFWPGEYFWYAGGVPAIMEEIKEFLHLDVMTVTGKTLEE
                     NLKDLQLNGFYKNCHKYLPALGVKVGDIIKPLHTPIKAQGAIAILKGNLAPEGAVVKHS
                     AISPRLMQVTLKARVFDCEENAIEAVLQKKIHPGEAVFIRYEGPKGSGMPEMFYTTEAI
                     ASDPELVETIALITDGRFSGATRGPAIGHVSPEASEGGPIALVENDDLIRIDIPARTLD
                     IIGTDSIERSVEEIEKILSERRAHWIKPESQYKKGILDIYTHNSVSPMKGAYMEFFM"
     CDS             3465..4493
                     /locus_tag="ctg18_47"
                     /transl_table=11
                     /translation="MRKNISILVSLLILSLTACSDKGQYFEESGSVFHTSYHIKYKAKQ
                     ILTDKIDSELQRFNLSLNPFNPNSTIAKVNNNEDVEVDEWFTEVFNKAEEISKKSGGAF
                     DITCAPLINLWGFGFSKMDSVTPQMIDSIKAFVGYQKVRLEGKKIIKEDPRILLNCSSI
                     AKGYACDVIARLLEKEGVKNYMVEIGGEVTMKGVNQQGDCWRVGINKPEIGTSGVTNDV
                     EEIVQLCQKGGVATSGDYRNFYIKDGKKYAHTINPATGYPAGQNILSATIVAEDCMTAD
                     AYATTFMVLGVEKAKLLAQSIPQIEYFIIYADNNGQQKVTYSKGMLEYLPNRKTLAILE
                     NP"
     CDS             4502..4879
                     /locus_tag="ctg18_48"
                     /transl_table=11
                     /translation="MKRYLNQLECKILRAGDSLFNTTTTDNLLIFVFSGKLIIYSQEGT
                     HIAEVAKDHFMLLAQNTNHKVIASAPTRLILIHAGSLSDMIINDPEWNVEKPVVLPIPP
                     ALAHTLNQIEYYMKDKYFTLN"
     CDS             complement(4882..5463)
                     /locus_tag="ctg18_49"
                     /transl_table=11
                     /translation="MLENLKKYKIVLASNSPRRRNLLSGLDIDFEVRVISDIDESYPDS
                     IDSMEIPLYIARSKAEAYKPTMADDELLITADTIVWTFDGVMGKPANREEAYAMLHALS
                     DHVHQVITGVCIMTKDKNVGFSVESAVCFAKLGDEEINYYLDKYKPYDKAGGYGIQEWI
                     GYIGVEAINGSFYNVMGLPVQKLYQELKHF"
     CDS             complement(5501..6022)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_50"
                     /sec_met_domain="HAD_2 (E-value: 3.3e-08, bitscore: 26.4,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSINYDLRKIKAFVFDVDGVLSCDVIPLHPNGDPMRTVNIKDGY
                     ALQLAVKKGYEVAIITGGYTEAVQIRFSRLGIQHIYMRSAVKVHDFKDFMEKTGLSPEQ
                     IMYAGDDIPDYEVMTRVGLPVAPADAAPEIKEVAKYISSRRGGEGVARDVIEQTMRAQG
                     HWFGEEAFGW"
     CDS             complement(6015..6782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_51"
                     /sec_met_domain="F420_oxidored (E-value: 8e-09, bitscore:
                     28.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVFVGAGNLATRLSLEMRKSGMSIGQVYSHTSEHAKILADELG
                     CGWTVIPEEIVEDADLYVFSLKDAVLQDVIARVKPNNGLWVHTAGSMPISVFEGLTARY
                     GVVYPLQTFSKSREVDFKKIPFFLEANSSEDEKVLGEVARALSSDVRFLSSEKRKNLHL
                     AAVFACNFTNHMYALAEKILEEQQIPGEVLLPLIDETAAKVHVMSPAQAQTGPAIRYDE
                     NVINKHMAMLKDPDMRNLYELISRSIHKEARHE"
     CDS             complement(6779..7339)
                     /locus_tag="ctg18_52"
                     /transl_table=11
                     /translation="MESFATLIQNRRSTRKFTEQLLSPEQVELILKAALMAPASKRSNP
                     WQFVVVEDKEMLKKLAGCKKNGSAFLEGCALAVVVLANVMESDVWIEDASVASIYMQLQ
                     AEDLGLGSCWCQIRNRVTEDEVDSNNYVRSLLDIPYQLDVLSIIGIGYKDQVRKPFDES
                     HLQWEKIHIGKFSLPEENKETGE"
     CDS             7461..9872
                     /locus_tag="ctg18_53"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISVIYSCLGYNKAERIIPSAQADMRLNVQMNNTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYDP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPDDDASA
                     AMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRGFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             10001..10411
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_54"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.1e-26, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             10448..12001
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_55"
                     /sec_met_domain="CT_Btheta (E-value: 8.1e-292, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12023..12916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_56"
                     /sec_met_domain="OAD_gamma (E-value: 3.1e-11, bitscore:
                     36.4, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLLMVLFSMGAKAQLTTSVKLNEVLVVNEDNFVDDY
                     GKRHPWIELYNNSAGTVDLRGCFLTNDKSNPKKYMIPKGDVLTKIPPYQHALFWADNEP
                     TKGTFHVNFTLDPNKDNYLALYDSDGTTLIDEVTIPAGQKADISYGLDLDGKGKWATLG
                     KVTPSTNNLTLDSNAKLENFQRNDPWGIGMTITAMAVVFLGLMILFLVFKQIGNAAIKA
                     SKRNAQKAAGTGAAVSANIGQESGEIFAAIATALYEMSDDNHDIENTVLTIHKVQRSYS
                     PWSSKLYSLRQTPNKK"
     CDS             12940..13371
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.7; E-value:
                     3.5e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_57"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.5e-20, bitscore:
                     63.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNTYKVHINSVVDDVAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTNASGEPVITRQAAPSVAGAVKSPLPGVILSVDCKVGDTVKRGQKILV
                     LEAMKMENNINADRDGKIVEIKVNKGDSVLEGADLVVIG"
     CDS             13376..14536
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_58"
                     /sec_met_domain="OAD_beta (E-value: 5.1e-153, bitscore:
                     501.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLQFLGENIQIFLSYTGFANATPGHIVMLLVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQLGIYEEGSVLNILYQGVKQGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYIIALQMGFDPSQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERVIRMKPPRAVSQTEKIVFP
                     IVGLLLTAFLVPSGLPLLGMLFFGNLIKESGVTRRLAETARGPLIDVITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKEGNKINPLIGNSGVSAVP
                     DAARISQNVGLEYDPSNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(14603..14749)
                     /locus_tag="ctg18_59"
                     /transl_table=11
                     /translation="MRKKSVNTLLVFGVVVAIILLMIWLFLGTTLVEDTSTEITPVPIE
                     QTN"
     CDS             complement(14818..15534)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_60"
                     /sec_met_domain="Peptidase_M22 (E-value: 2.7e-27, bitscore:
                     88.7, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYME
                     EALEAAKSKGIKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILASAA
                     IRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGKVCF
                     FGDGAAKCETVITSPNACFIDGIYPLAVNMASLSQKAYDDGRFENVAYFEPFYLKEFQA
                     TIAKNKVLNEALGKNK"
     CDS             complement(15626..16246)
                     /locus_tag="ctg18_61"
                     /transl_table=11
                     /translation="VKQRIDLFPDRAYERLFTLVSEYVPVSDRFRELIYERSYMVSFAK
                     EELLQEEGKLCNSLFFIAGGFCASYYSTVTKECILGFFEEGQFCTSWYSFQSKRKSFMA
                     IKAVVDTAAVVISYEHYDFILRECPEFAYVICRVLSNIIQVGEERSYVLRSRSARGRVQ
                     YYKDNHDIYYLMKHVPQYSIASFLNMTPETFSKIISERDKDRK"
     CDS             16733..17029
                     /locus_tag="ctg18_62"
                     /transl_table=11
                     /translation="LVSEKKEGQSVPLAQCKLIFTETSNGGNAYKLTEVYTSKKNQSNY
                     SLMSNTIVMRLKITGDNMENQYTVVELNNKKMILTFVYFLEETSSGELIFEKE"
     CDS             17273..18172
                     /locus_tag="ctg18_63"
                     /transl_table=11
                     /translation="MNRIALLLLLLIGAFSMRAQTTETTGKEIVFVNEFKGSGNLEGST
                     IAAIRNNIIEGLIDAKRLIVKDLKSDAQFQAEMTKRAADASVSEEEYGFTVLRNMNARW
                     VIAGTVTRVEAVRKKNSDGKYFYDAAIDVSANIIDVATGTITETKTITTDGGGLLSGFT
                     EGTTIGDTDNEAIASACLVLKSRAKAFVEEFFTLKGAILEVASEKKGKAEEVYISLGET
                     SGVKKGDIFEVFEQRVIVGRKSRKKIGELKVKTVEGDDISLCNVTKEGKVIFEKIQALE
                     ENQSLSIESRPKTQNVLF"
     CDS             18242..19528
                     /locus_tag="ctg18_64"
                     /transl_table=11
                     /translation="MRNKFILYLYSYIIGIGLIIPNTILGQSSENFTNDATLVSDQGRT
                     AIILSSGIHEKKKEAVAMAILSAFDTYFFSGIAGLNEDMPLIGELETQEQKDYVKRIFK
                     ENRYTQFIGLVTEVNGSPEKMPTRQFKATIQFELKTDALYKDMLRSKVIKKDLERMNTT
                     EIRQEIPQFTLTVVPFKPEGTTYSNILKNDYEIRNAITRIEAMLKTKKYEVKDFLAVVA
                     SVERDLQFEMDKTVMSNDKQLINQTQADVYITVDLANNRRPDGGMGVVNLKAYEVSTGN
                     LLSSAEGKSKRYRDYIIANLYDRALENCLDGFIQQLTSNWASKITDGNQYAINFSIAPE
                     SAIDMSTEVGSMGFPLADVLTLWIKMHAFNGKYHLAGSVDEYIKFDQVQIQQGQEQEFI
                     LSLYTYLRDELGISCNRRQSGKTYYITIQ"
     CDS             19533..21407
                     /locus_tag="ctg18_65"
                     /transl_table=11
                     /translation="MRYIIALISWLLISSLSITIHAEKKPDWLAERPNGTFFYIGIGSA
                     SKSSPNYQQVAKQNAIAELVSEIEIKVEANSLMTTLEKEDESVSSYFSEIIQTSVKQHI
                     KNFEQVDNWQDEQNYWVYYRLDKETYAEQVQKRRELAIRQGFDFWYNGENTLRQGDLLT
                     AIDLFMQGLTAIEPCVNEDLSCSYEGQTILVGNALYTSLQSVFDGIQLKPSNSEIQASA
                     FQASRTPIILTIHKNNIPLRNLPIKGEFNSGGGSLSEIIPTDDNGETTVYLQNITSKNT
                     NQEILFTLDIHPFTQIKNPLFNTLKQQLSANTPRCQVLVSSDSEKNIRAYIQSKQQGNE
                     GLVRGIHNLLTNNYFDITDSQNKADVLILIQSDFSQGNIVEGDIYNMKEYFTTISIQIK
                     NNRSGAILLNYLLEKKRTLSPANTSIANARNSAIREAMKIINRELGKQLKDVKIDTNGE
                     IPQVNDTPKAPKRPSHVSTPPNQPVIVIHPKPTSQTPVEKPQSTVSPTLAKKKAEAELE
                     PGIFISYNGKKEMNDRTFLKFSIENKNQEDYKLGLYNRELLIVNGNGEEMKCITVKIGS
                     KSDSYDIQATIVPNTPTLLEVEIMKTGKIALFQLTNTNRRTIKLRNLE"
     CDS             21471..22028
                     /locus_tag="ctg18_66"
                     /transl_table=11
                     /translation="MKRLNYVMGMAMGIVFLLTACGGPKSVAQQDVAVIVPCSGPEYMT
                     NSQYIRASAMGLSTDMTIAKKKAQSSARTEIATAIEAKVKAMVEDYTSSYQNGENDESK
                     RRFQDIARTTVLQKLNGLRTICEQTMKTPDNKYKVYIALELAGNELLEGISNSIKNDDK
                     LRIDFEYEKFKKVFEEEMSKEN"
     CDS             22129..23064
                     /locus_tag="ctg18_67"
                     /transl_table=11
                     /translation="MSKRLIHLVLFLSGFSALFAQDNENYTQSYHWASGYLENIPHDFP
                     LALRDEETMGTSDPGLCPEIAREQAIQRALFLYSLKRGSRMSMLTDYFIINQVATNMND
                     YKHEKMMVMATLHSEPQTYSFSVIREHTSIYGEQFVWLTVNSQGKEQRTLSSFYEFMLS
                     TSKESHERQEQRLSLSIRCYNDSILKNHSFTLKGNKEKLIISTQINDLLLPLPTDLYLY
                     KDKGTQLAQEKKEYPLSSGYWSTLLESLSDALTNFDFPGVTIQEVFESYQDTNQQLYRE
                     KTCCSLSARPVILSILNNHIFLDWSIQTIQ"
ORIGIN
        1 aaagatatga cccgttgtct aagacgatcc ccacgaaatt attcaacgca acagctcgta
       61 aattctcggg aataaagaac ttacacgatt tcaattgcgg attgaaagcg tataagaatg
      121 ttgtcattaa aaatatagag gtgtataacg atatgcaccg ttacatacct tatttagcta
      181 agattgccgg atttcacaag attggcgaga aagtagtgaa acatcaagcc cgcaagtacg
      241 gaactactaa attcgggttg gatcgcttcg tgaacggtta tcttgatttg atcacgcttt
      301 ggtttacttc caaattcgga aagaaaccga tgcacttctt cggtttatgg ggaagcgcta
      361 tgttcttcat tggttttatc gctctagtaa tcgtactcag catgaaattg atctcgatgt
      421 actctggaga tctaagacct ttggttacaa gttcccctta tttctatatt tcattgacag
      481 cgatgattct gggaacccag atgttcctag cgggctttat cggggagttg atttcccgca
      541 attctccgaa tcgcaataac tataaaatag aggatgagat atgagtttcc tagaattagc
      601 gagaaaacgt tgctctatcc gaaagtatgc ccccaaaaat gtagagcaag aaaagattga
      661 ttatatccta gaagcagctc gtttggcccc ttcggcggta aattatcaac cttggtattt
      721 tgtatgggtt caaagcgcgg aaggaaaagc taaattacaa gaatgctatc cccgggaatg
      781 gttcaagcaa gcgccttatt acttgatcgt ttgcggagat catcagcaat cttggaaacg
      841 gggcgatcat aaggatcata tggatatcga tacggctatc gccacggaac acatttgttt
      901 agccgctgcc gaacaaggat tgggaacttg ttgggtttgc aatttcgaca cggagctttg
      961 ccgtaaacat tttaaaattc cggaaacgat cgagcctgtt gtactgatac cattcggcta
     1021 tccttccgac ccggcattat tcgatgagac tccaaagaaa cgtaagccca tagaagaaat
     1081 tattaaacgg gaatcattct agtatgttat acattgaagt tctgctacta gcgatcggct
     1141 tatccatgga tagcctagca gtatcagtta ccggcggcgc agttcttaag aacaactgca
     1201 ccgccggtaa tattattaag atagcgagcg tgctcggtat attccaagcc ggaatgaccg
     1261 tgatcggtta tacgatggga ttaggattcg aaaaatacat ttgcgccttc gaccattgga
     1321 tcgcatttac cctcttgctt tacttaggtg gaaaaatgat atacgatagc acgaaggaag
     1381 aggaggaaga cgggaaattc gatcctctat gtaaccggac attatgcgga ttgggaatag
     1441 cgacaagtat cgatgccctc gccgtaggaa tctctctagc gatcttaaaa tcaccgctct
     1501 tgctgcaagc ctcgactatc ggtgttgtca ccttcgctat ctctgccttc ggtgtctatt
     1561 tcggtaaccg attcggcaag agaatcgact tgaagctgga cctcatcgga ggtttaatct
     1621 taatcggtat cggtacaaag attttgatag agcatgtatt ctttagctag ggatacctta
     1681 ttgaataaat aaccttatac attaattaat agacatgaaa agccagcaat tacgaaaact
     1741 agcgccggag ctggattcac tccggctagg cagcggttgg aaaatcgacg aattgagtaa
     1801 accgcaaatc attgtagaaa gcagttacgg acatagccat ccgggaagcg cccatctgga
     1861 taaattggtg gacgaggccg gaatcggtat aaaggaaaag gggggacgtg ccgcaaacta
     1921 cttcgtcact gatatttgtg atggagaggc gcagggacac gatggtatga actactcatt
     1981 agtctcccgt gatatcatgg ccgccatgat agagattcat gtaaaagcga ctcctttcga
     2041 cgctggtgtc tttatagcca gttgcgacaa atccgtccct gcgcatttga tggcgatagc
     2101 ccggctagat atgcctgcta tattcatgcc cggtggtata atgaaagccg gtcccaacct
     2161 actcacgtta gaacaaatcg gtacctatag cgcccaatac gagcgaaaag aaataacgga
     2221 agaacaattc atggtttata agcgtgacgc atgtccggat tgtggagctt gctctttcat
     2281 gggtaccgcc tctacgatgc aagtaatggc agaagcgctt ggcatcgctt taccgggctc
     2341 cgccttgatc cccgcccatt tacccgagtt aaaagaaacc gcccgtaaag ccggagaaca
     2401 tgcactcgga ctggcgaaag aagagttaaa accctccgat atcatgacga tacaagcgtt
     2461 tgaaaatgcg atcatggtac atgccgccat agcgggttcc agcaacagcc tgcttcatct
     2521 tccagctatc gcccatgaac tgggaatcca gttatcaccg gatttgttcg acaagataca
     2581 tcgtaagatc ccctaccttt taaatatacg tcccagcggt ttttggcccg gcgaatattt
     2641 ctggtatgcg ggaggcgtac cggcgatcat ggaagaaatt aaagaattcc tccatctcga
     2701 cgtcatgact gttaccggca aaacattgga agaaaactta aaagatttac aactcaacgg
     2761 cttctataag aattgccata aatatcttcc tgccctagga gtaaaggttg gcgatattat
     2821 caaacctctt catacaccga tcaaggcaca aggagccatc gctatattga aaggaaattt
     2881 agcgcccgaa ggggcagtcg taaaacattc ggcgatttca ccccgcttga tgcaagtcac
     2941 cctgaaagcg agggtattcg attgtgagga gaacgctatt gaggcggtat tacaaaagaa
     3001 aatccatccg ggagaagcgg tatttatccg ttatgaagga ccgaaaggaa gtggaatgcc
     3061 agaaatgttt tatacgacag aagcgatcgc ctccgatcct gagttggtag agaccatcgc
     3121 attgatcacc gacggtcgtt tctccggagc gacccgaggc ccggcgatcg gacatgtatc
     3181 cccggaggct tccgaggggg gaccaatcgc cttggtcgag aacgatgact tgatccgtat
     3241 cgatattcca gcgagaacat tggatataat cggtaccgac agtattgaga gaagcgtgga
     3301 agagatagaa aagatcctat ccgaaaggcg tgcacattgg ataaaaccag agtcacaata
     3361 taaaaaagga atccttgata tttatacaca caatagcgtc tcccccatga aaggggcata
     3421 tatggaattt tttatgtaag ttcgcgacat aaaatttcat aatgatgcgc aagaatattt
     3481 ccatattagt cagcctgttg atcttatcgc ttacggcttg ctcggacaag ggccaatatt
     3541 tcgaagagag tggttctgtt tttcatacaa gttaccacat caaatacaag gccaagcaaa
     3601 tcctaaccga taagatcgac agcgagctgc aacgttttaa cctctcctta aatcctttca
     3661 accccaactc cacgatcgct aaagtcaata ataacgagga tgtggaggta gacgaatggt
     3721 ttaccgaagt attcaataag gcggaagaaa tctccaaaaa atcaggagga gcttttgata
     3781 ttacttgcgc tccattaatt aatctatggg gattcggatt cagtaagatg gacagcgtaa
     3841 ccccgcagat gatcgatagc atcaaggctt tcgtcggtta tcaaaaagtg agattggaag
     3901 gaaagaaaat catcaaagaa gatccccgga ttctattgaa ttgttcgtcc atcgcaaaag
     3961 gttatgcttg cgatgttatc gcccgcctgc tggaaaagga aggcgtaaag aactacatgg
     4021 tagaaatagg tggtgaggtt accatgaaag gcgtaaatca acaaggtgac tgttggcgag
     4081 tcggcatcaa caagccggaa atagggacaa gtggcgtaac aaatgatgtt gaagagatcg
     4141 tacaattatg ccaaaaaggg ggtgtggcta cttctggtga ctaccgaaac ttctacatca
     4201 aggatggtaa gaaatatgcc catacgatca atccggcgac cggttatccc gctggacaaa
     4261 atattcttag cgcgaccatc gtggcggaag attgtatgac agcagacgct tacgctacga
     4321 ctttcatggt tttaggagtc gagaaagcga agctactggc acaatccatc ccccaaatag
     4381 agtatttcat tatttatgcg gacaacaacg gacaacagaa agtcacctac tcaaaaggta
     4441 tgttggaata ccttcctaac agaaaaacat tggctatcct cgaaaatcct taagttccta
     4501 catgaagcgt tatctaaatc aacttgaatg caaaatactg agagccggag attccctgtt
     4561 taataccaca accacggata acctattaat cttcgtattt tcgggaaaac ttattattta
     4621 cagccaagaa gggacacata tagcggaagt ggcaaaagat catttcatgc tacttgcgca
     4681 aaacaccaat cataaggtta tagcctcagc ccctacccgc cttatcttaa tacatgcggg
     4741 cagtctatcc gacatgatca taaatgaccc ggaatggaat gtggaaaaac cggtcgtctt
     4801 accgattccc ccagccttag cgcacacatt aaatcagata gaatattata tgaaggataa
     4861 atactttacc ttgaattgag attaaaaatg tttcaattcc tgataaagct tttgcacagg
     4921 taatcccatc acgttataaa agctaccatt gatagcctct accccaatat aaccgatcca
     4981 ctcctgaatg ccataccctc ccgctttatc ataaggttta tatttatcca aataataatt
     5041 aatctcttca tcacccaatt tagcgaaaca aaccgcagat tcgacggaaa agcctacatt
     5101 tttgtccttc gtcatgatac aaacaccggt tattacctga tgtacatgat ccgacaaagc
     5161 atgaagcata gcataagctt cctctcgatt cgcaggcttt cccataaccc cgtcaaacgt
     5221 ccaaacgatc gtatctgccg tgattagcaa ttcatcatcc gccatagtcg gtttataggc
     5281 ctccgctttc gaacgggcaa tatataaagg gatctccatg gagtcaatag aatccgggta
     5341 agactcgtca atatccgaaa ttaccctcac ctcgaagtcg atatccagac cagataacaa
     5401 attccgtcgt ctcggagaat tagaggctaa gacgatcttg tactttttta aattctctaa
     5461 cataacctat tcgattaagc gttacacatt caccaaaatt ttaccaccca aaagcctcct
     5521 cgccgaacca gtgtccttgc gcccgcatcg tttgctcgat cacgtcccta gctacgcctt
     5581 cgccacctcg ccgggaggat atatatttcg ctacctcctt gatctccgga gccgcatccg
     5641 caggtgccac cggcaatccg actcgcgtca ttacctcata atcaggaata tcatcacccg
     5701 catacatgat ttgctcagga gacaagcccg ttttttccat gaaatcctta aagtcatgca
     5761 cctttacagc gctacgcata taaatatgct gtatacccaa acgagaaaag cgaatctgta
     5821 cggcttccgt atatccgccc gtaattatag cgacctcata acctttcttc acggccaatt
     5881 gcaaggcata gccatccttg atattgaccg tacgcatcgg atctccattc gggtgaagcg
     5941 gaatcacatc gcaggatagc accccgtcta catcaaagac aaaagccttt atttttctca
     6001 aatcatagtt tatactactc atgtcgagcc tccttatgta tacttcggct aatcagctca
     6061 tatagatttc gcatatccgg atctttaagc atagccatat gtttgtttat cacattctcg
     6121 tcatatcgta tagctggtcc cgtttgggct tgcgccggcg acattacatg taccttagcg
     6181 gctgtctcgt ctatcaaagg tagcaagacc tctcccggta tttgctgttc ttccaagatc
     6241 ttttcagcta gcgcatacat atgattcgta aaattacaag cgaaaaccgc cgctaaatgt
     6301 aagttctttc gcttctcgga ggagaggaaa cggacatcac tggagagcgc cctagccacc
     6361 tctcccagca ccttctcatc ttcagacgag ttcgcctcta aaaagaacgg tattttcttg
     6421 aaatccacct ccctactctt actaaacgtt tgtaacggat aaaccacccc atatctagcc
     6481 gtaagacctt caaatacaga gattggcata ctccctgccg tatgcaccca caaaccgtta
     6541 ttcggtttta cacgggcgat aacatcttgg agcacggcat ctttcaaaga gaaaacatac
     6601 aagtcggcat cttccacaat ctcttccggg atcacggtcc acccacatcc caattcatca
     6661 gctaaaatct tagcatgctc acttgtgtga ctatatactt gcccgatact cattccggac
     6721 ttacgcattt ccaacgaaag ccgggtagct aagtttccgg caccaacaaa tacgactctc
     6781 attctcccgt ctctttattt tcttccggaa gagagaactt tcctatatgt atcttctccc
     6841 attgtaaatg ggattcatca aaaggcttac gaacctgatc cttataaccg ataccaatga
     6901 tagacaagac atccaattga taagggatat ccagcaacga acgaacataa ttattcgaat
     6961 ccacctcgtc ctctgttacc cggttccgga tctgacacca gcaactgccc aatcccaaat
     7021 cctccgcttg caattgcata taaatagaag cgaccgaagc gtcctcgatc caaacatcgc
     7081 tttccatcac attcgccaag acaaccacgg ccaaggcaca accctccaga aaagcggaac
     7141 catttttctt acacccggca agtttcttca acatttcctt atcttccacg accacgaact
     7201 gccaaggatt actacgtttt gaggccggag ccatcaacgc cgccttcaag atcagttcta
     7261 cctgctcggg tgaaagtagt tgttcggtaa acttacgtgt acttcttcta ttttgtataa
     7321 gtgttgcaaa actctccatt tttttcgttc tttgtactct tttaatatta agattcgcaa
     7381 atataaatat aattttttgc acccatatat acgtatcgtt cttttttctc gttagtattt
     7441 ttataattga acaatagatt atgaagattc gtgcgatagc cgcgctgcta tttatactta
     7501 tttccgtgag tgcctttggc gagggccgca taaaaatcac tggttatgtc cgtgacgccg
     7561 acggtaaccc cctggaatta gtgaatgtcc gggttaagaa cacgttgatc ggctccatga
     7621 ccaacgagaa gggatattat tccttttcca tatcgccggg ggattctatc tccgttattt
     7681 actcttgtct gggatataat aaggcagagc gtatcattcc ctcggcacaa gcggatatgc
     7741 gcctgaacgt acagatgaac aatacctcat ttgatttagg ggaagtatcc gttactgcca
     7801 tccgcaagca gaccacgacc atggagtccc taaacgcgga caaaatcaag ttattgcccg
     7861 atccctccgg aggtagtata gagagcttgg tcgttacgtt tgccggcgta tcgtccaata
     7921 acgagctaag ttcccagtat tccgtacgtg gaggtagtta tgatgaaaat atcgtttatg
     7981 tgaatggtat cgaggtattc cgtccgcttc tgattcgctc gggacaacaa gagggcctta
     8041 gctttatcaa tccggaccta acggaggcgg tcaatttcgc cgccggtggc ttcgaggctc
     8101 gttacggaga caagatgagt tccgtgctgg atattaccta taaaaagcct aagatattcg
     8161 aaggctcggc ttccgcgagc ttgttgggcg caaatgctta tgtaggcagt tctatcggta
     8221 aatttaccca agtaacgggt ttccgcttta aaagcggtcg gtctattttg ggtaccatgg
     8281 atacagacgc tgaatacgac cctaaattta tcgatctgca aacttacatc acgtaccaat
     8341 tggcccctaa atgggaaatc aatttcttgg gaaacctcgc taacaataat tataaattca
     8401 ccccttatag tcgggaaacc tctttcggta cagccgagca tcccaagaac ttcaaagtct
     8461 atttcgacgg aagggaaaga gaccgtttcc aaaccttatt cggtgcgctt acattgaaac
     8521 acaaccccaa tgagaacaca gagttgggac ttcaagcctc cgctttcaaa agcaaggaag
     8581 aagagggata cgatatcgcc ggagaatatt ggctgagcga gaacggagcg gaaaatccgg
     8641 atgacgacgc gtcagccgcc atgtccgtag gccgttatca cgagcacgca cgaaaccgtt
     8701 tgaactccac cgtcatgaat gtcgggcact atgggatggc ccgcctttta aacaatacgt
     8761 tgaaatgggg agccacggta caaatggaga aaatcaatga taagatcagt gaatgggaaa
     8821 aaagggattc ctcaggttat tctttgcccc aaaccggtaa taacgtaagt gtatattcga
     8881 acctcttttc tgataatcag atagaaagca cacgcttttc cgcttatgcg caagacgcat
     8941 tcaaattcag gaccaagcaa ggtctgttca cgttagtcgc aggggttaga ggtagttatt
     9001 ggacttataa taaggagttc cttttcagtc cccgtgcctc attgggcttt atcccgaact
     9061 tcgaccaaga cttgacgctc cgtttcgcca ccggactgta ttatcaatcg cccttctaca
     9121 aggaattacg tagagtagac aaagataaga acggcaataa tatcacggta ttgaacaaag
     9181 atctaaagtc acaacgctcc atccatttca tattgggagg agattatacg ttccgtgccg
     9241 tagaccggaa tttcaaggtg accgccgaga tgtactataa aaagctggac aatctgaatc
     9301 cctacaccgt agataacgtc aagatccgct attacggtga gaactgcgcc aaaggttacg
     9361 ccatgggact cgatgtcaaa ttcttcggag aattcgtacc gggtaccgac tcatggatca
     9421 gcttctcctt gatgaaagcc cagcaaacca tccgggaaac aacgaccgtt cctatggcca
     9481 atagccaagg ctacaacatc tcactcttct tccaagatta tttcccgggc tataaacgag
     9541 tcaagctaaa tctgaaagga gttctatccg gaggacttcc ccagacaatc ccgggcaaag
     9601 gatacgaagc cggctatttc cgtacgcccg cctacaaacg tgtagatatc ggcctctcct
     9661 atcaattggc aggaggcacg gacgctatca tggacagggg cttcttccgc catttgaaaa
     9721 acatttggct aggtctggat gtatttaaca tattagacat caaaaacgtt agttcctact
     9781 attggataac agatgtatat aatgtccaat acgcagttcc aaactatctg accggacgtc
     9841 aattgaacgt tcgtctgatt gtcgattttt aataaaatgt atctttaaac acatttactg
     9901 ggagataaaa acaaaaaatt atttcctcat tcataaaaag tagtgtacat ttgcacacaa
     9961 tagaaacaaa catttactaa atctttaaat tattattgac atggaactta cacatatcga
    10021 acatttaggt atcgcagtga agagtatcga ggcttgttta ccctattatg aaggcgttct
    10081 tggattaaaa tgctacaata tcgaagtagt agcagaccaa aaagtaaaaa ccgcattttt
    10141 caaggtagga cagactaaga ttgaattact agagccgacc agcgaagata gcacgatcgc
    10201 aaaatttatc gagaaaaaag gtgaaggtat ccaccatatc gcattcgcgg tacctgatgt
    10261 acaggcagct ttgaacgagg ctgaggaaaa aggcgttaaa ttaatcgata aagctccccg
    10321 tggtggcgcg gaaggcttga acatcgcttt ccttcacccg aaatcaactt gcagcgtatt
    10381 gacagagctt tgcatgccgg gcaacaaata attaatccgt tcatttctaa caacaaatca
    10441 aaatacaatg agtaaccagc ttgaaaaagt aaaagagctc atcgcacttc gtgagcaagc
    10501 tcgcttgggt ggaggagaga aaagaatcga atcacagcac aaaaaaggca aatataccgc
    10561 tcgtgagcgt atcgccatgt tgcttgacga aggtagtttc gaggaattcg acatgtttgt
    10621 tcaacaccgt tgtacaaact tcggtatcga gaaaactaaa tatttaggcg atggtatcgt
    10681 aacaggttat ggtacgatcg acggacgttt ggtatatatc ttcgctcaag atttcaccgt
    10741 attcggtgga gccttgtctg aggctttggc tatgaagatc tgtaaagtaa tggatcaagc
    10801 catgaagatg ggcgctcccg ttatcggttt gaacgactcc ggtggagctc gtatccaaga
    10861 aggtgtaaac gccttggcag gatacgcaga gattttccaa cgtaacatct tggcttccgg
    10921 tgttgttccc cagatttccg gtatcttcgg cccttgcgcc ggtggagccg tttattctcc
    10981 ggctttgaca gacttcaaca tcatgacacg tggtaccagc tatatgttct tgactggtcc
    11041 gaaagtcgta aaaaccgtaa caggtgagga tgtaacccaa gagcagttgg gtggagccag
    11101 cgtacacact accaaatcgg gtgtagccca tttcgctgtc gatacagaag aagatggttt
    11161 gcaattgatc cgtaaattgc tcagtttctt acctcagaac aacttagagg aaacgccgtt
    11221 agttgagtgc aaagacccga tcgatcgttt ggatgatgta ttgaatgata tcattcccga
    11281 taacgctaac caatcttacg atatgtacga ggttatcggt acgatcgtcg ataacaacga
    11341 gttcctagag gtccatgcgg actacgctaa gaatatcatc gtaggtttcg ctcgtttcaa
    11401 cggacaatct gtcggtatcg tagccaacca gccgaaggtt atggcaggat gcttggatag
    11461 caacgcatct cgtaaagcag gtcgcttcgt tcgtttctgc gacgctttca atattccttt
    11521 ggtaacattg gttgacgttc cgggattcct tccgggtaca ggtcaggaat acaacggtgt
    11581 aatccttcat ggcgctaaat tgctttacgc ttatggtgag gctaccgttc ctaagattac
    11641 cgttacattg cgtaagtctt acggtggagc ttattgcgtg atgagttcta aacatttacg
    11701 tggtgatatg aattacgcat ggccgacagc cgagatcgcc gttatgggcc cgagcggtgc
    11761 cgtagaggtt atcttcgcca aggaagtagc agccgctgaa gatccgaaag catgcgcagc
    11821 agagaaagaa gctgaatata agaaagcatt cgctaatcct tataacgcag ctcaatacgg
    11881 ttatatcgac gatgttatcg aaccgcgtaa cactcgtttc cgtattattc gtgctttgca
    11941 gcaattgcag actaagaagt taagcaatcc tgctaagaaa catgataacc tgcctctata
    12001 atccgtaaaa caggagatga atatgataaa taagaaaata ggggtattgc tactgttaat
    12061 ggttctcttc agtatggggg ccaaggcaca gttgactacc tccgttaagt taaacgaagt
    12121 attggttgtc aacgaggata acttcgttga tgactacggt aaacgccatc catggattga
    12181 gttgtataat aactcggccg gtacggtgga cttacgcggt tgttttttga cgaacgataa
    12241 aagtaatcct aagaagtata tgataccgaa gggagacgta ttgacaaaga tacctcctta
    12301 tcagcatgca cttttttggg cggacaacga gcctacaaaa ggaacatttc acgtaaactt
    12361 tacgcttgat ccgaacaagg ataattatct agccttatac gattcagatg gtacaacgtt
    12421 gattgacgag gtaacgattc ctgccggaca aaaggcggat atcagctacg gtttggactt
    12481 agatggtaaa ggcaaatggg caactctagg caaagtgacc cctagtacca acaatctaac
    12541 gctagattcg aatgcgaaac ttgagaattt ccagcggaac gacccatggg gtatcggtat
    12601 gaccattaca gccatggctg ttgtattcct tggcttgatg atcttgttcc ttgtattcaa
    12661 acagatcggt aacgcagcga tcaaagctag caagcgtaac gcccaaaaag ccgcaggaac
    12721 aggtgctgcc gtatcagcca atatcggtca agaatcaggt gaaatttttg ccgctatcgc
    12781 taccgctctt tatgagatga gcgatgacaa ccacgatatc gagaacacgg tattaactat
    12841 ccacaaggtt caacgcagct attcaccatg gagttctaag ctttattctc tgcgtcagac
    12901 tccaaataaa aagtaatcat cctaaaatcc aattgacgaa tgaaaagttt taaatatacc
    12961 attaacggta acacatataa agtacatatc aactcagttg tagatgatgt ggcagaggta
    13021 gaggtaaacg gaacccctta taacgtaaaa atggagaaac ctgcgaaaaa acaaatggtt
    13081 acattgaaac gtccggctca agctccgacc aatgccagcg gtgaacctgt tatcacccgt
    13141 caagcagctc caagtgtagc cggcgctgtt aaatctccgc tgccaggtgt aattttaagt
    13201 gtagactgta aagtcggcga tacagttaag agaggtcaaa agatcttggt attggaagcc
    13261 atgaagatgg aaaacaacat caatgccgat cgtgacggta aaattgtaga aattaaagta
    13321 aacaaaggcg actctgtatt ggaaggtgca gatctcgttg taatcggtta atgatatgca
    13381 agaaagtttc ttacaattcc taggagaaaa tatccaaata tttctctcct atacaggatt
    13441 tgcgaacgcg actccagggc atatcgtgat gctattggta ggtttgctgt tcatattcct
    13501 agcgattaaa tatgaattcg agccgatgct tctgatccct attggtttcg gtatcttgat
    13561 cggaaatatc cctttcaagg atgccggatt acaattaggt atatacgaag agggttctgt
    13621 attgaacatt ttgtaccaag gagtgaaaca aggttggtat ccccccttga tattcctcgg
    13681 tatcggtgcc atgacagact tctccgcttt gatatccaac cctaagttaa tgctagtcgg
    13741 agctgccgcc caatttggta ttttcggtgc ttatatcatt gcattgcaaa tgggatttga
    13801 cccaagccaa gccggtgcta tcggtattat cggaggagct gatggtccaa ctgcaatctt
    13861 cttgtcatcc aagttagctc ctaacttgat gggtgctatc gctgtatccg catactcata
    13921 tatggcattg gttcctatta tccagccacc gtttatgaga ttgcttacaa cgaagaaaga
    13981 acgtgtgatc cgtatgaaac ctccaagagc cgtttcacag acggagaaaa tcgttttccc
    14041 gatcgttggc ttgttattga cagccttctt ggtaccgtct ggtttgccat tgttaggaat
    14101 gttgttcttt ggtaacttga tcaaggaaag tggtgttact cgccgtttgg cagagacagc
    14161 ccgcggcccg ctgatcgatg ttatcacgat cttattaggc atcacggtag gtgcttctac
    14221 acaagctacc cagttcttaa cattgaactc tatcaagatt ttcggtttgg gtgcgttgtc
    14281 attcgttatc gctacttgtg ccggtgtatt gttcgttaag ttctttaacc tgttcttgaa
    14341 agaaggcaac aagatcaatc cgttgatcgg taactccggt gtatccgccg tacctgacgc
    14401 tgcccgtatt tcccagaacg taggtttgga atacgatcca agtaactact tattgatgca
    14461 cgctatgggt ccgaacgtag caggtgtaat cggttccgct gtagctgccg gtatcttgct
    14521 aggattcctt ggttaataaa acaactatct atattaaaaa aggcgaggtc cgaaaggatc
    14581 ccgccttttt atgttattgt tctcagttag tttgctctat aggaaccgga gtaatctccg
    14641 tactcgtatc ctccaccaac gttgtcccga ggaacaacca gatcatcaaa aggattatag
    14701 cgacaaccac accaaatacc aatagcgtat tcacactttt ctttctcatg tctttaactg
    14761 atttattcat tttagaataa acagccggaa catgaatttg gttgtgtacc cttactctta
    14821 tttgtttttc cctaacgcct cgttcagcac tttgttctta gcgatcgttg cttggaattc
    14881 tttcaaatag aaaggctcaa aataagccac attctcaaaa cggccatcat catatgcttt
    14941 ctgcgacaag gatgccatat ttacagctaa tggatagata ccatctataa aacaggcgtt
    15001 cggagaagtg attaccgtct cacatttagc ggcaccgtct ccaaagaaac aaaccttacc
    15061 gttctctaaa aaagaagcat acgaatcagc atctacgata tcagcagtcg tggcacgtat
    15121 cgtgttgaga tgggaatcat aaatcgaaga gtagacttcc atacgacggg catccaacat
    15181 agcgcaatac aagcaatcgg cctcctcctt atttttccgg atagcggcag acgctaaaat
    15241 atccagcgta tgaataccga tcaaaggaat accataccca aagcataatc ctttagccac
    15301 agacaccccg atgcgtaacc ccgtataaga tccgggtccg ctacttaccg ccacggcatc
    15361 cagttttatc cctttcgact tcgcggcttc taatgcctct tccatataaa cgcccaataa
    15421 cgccgcatga gacggcccct cgaaggaagc cttctcaaag accacctcct ccccttccga
    15481 cagggctact gaacatacgg aagtggatgt ctcgatattt aagatcaatg acataataat
    15541 agactattaa cagttgatag ttagcatctc ttctatagga ataccaacat tataattaga
    15601 ttatgtcgca aaggtataca aaaaatcact ttctatcttt atcacgttcg gagattatct
    15661 tcgaaaaggt ttccggtgtc atatttaaga aagaagcgat gctatactgt ggaacatgct
    15721 tcattaaata atagatatca tgattatctt tataatattg cacccgtcct cgggcggatc
    15781 ggctacgcag tacatagctc ctctcttcac ctacttggat tatatttgac aagaccctac
    15841 aaatgacata agcgaattcc ggacattccc ttaatataaa gtcataatgc tcatatgaga
    15901 ttaccacggc agccgtatcc actaccgctt ttatcgccat aaaagatttt cttttacttt
    15961 ggaaactata ccaagaggtg cagaattgcc cctcttcgaa aaagcctaat atacactcct
    16021 tcgttaccgt actataataa gaagcacaaa aacctccagc aataaaaaaa agtgaattac
    16081 agagctttcc ctcctcttgt aataattcct ctttggcaaa tgagaccata tagctcctct
    16141 cataaatcaa ttcacggaaa cgatccgaga ctggtacata ttcactgacc aaagtaaaca
    16201 atctctcata agcccggtct ggaaaaagat ctattctttg tttcacaata gtttacgttt
    16261 agtatcattt aacaataaat ttagtcctat cggaactatt tcaaatagcg gaattacaat
    16321 atgctcaaat tgaaaaagat ataagaaaag ctcacttgcg gaaatatagt aggactataa
    16381 aatcgtattt ttattaaaat ttcaacaaaa agtaataggc tctacattat atatattgta
    16441 tttttgcgaa aatattattg tattagttcc gataggacta aagtatcagt atctacaaat
    16501 cccctcttaa cccgttatac cctagggcaa atcttaatat cggataagat ttatcttgta
    16561 tctaatcttt atatttggcc aacaaaacaa cttatgatta tggaaaacac aacaatcaaa
    16621 cgaaacaaga tattaattat catactccgt gacataccca agtccggaag aaatgatccg
    16681 ggcagaatca agcaataaac taacctagga caatctcaaa ggaacttggc gattggtttc
    16741 cgagaaaaaa gagggtcaat ccgttccatt agcccaatgt aaactcatct ttaccgaaac
    16801 atccaatgga ggaaacgcat ataaattgac cgaggtatac acatctaaaa aaaatcaatc
    16861 taattattcc ctaatgagta acacgattgt catgcgacta aaaataacag gcgataatat
    16921 ggagaaccaa tatacagttg ttgaactaaa caataagaag atgattctta ccttcgtcta
    16981 ttttctggaa gaaacctcat ccggagaatt gatattcgaa aaagaataac tcagtatttc
    17041 gacagaaacg gtttttaatc aaggattcac acaaaatagt gtctttatat tcggctagac
    17101 ctattactat gtgacattaa ttatcataca accgaaaagt taatctagga caagattttt
    17161 atccttttta ccttataatt ttgtaaaaaa attatatagc cgactcttga gtcatggggt
    17221 attacgaaga taacaaacat tattggcaaa taacattaaa caaaaaatga ttatgaatcg
    17281 aatcgcactt ctacttctct tattgatcgg agcgttcagt atgagagcac aaacaacaga
    17341 aacaaccggc aaagaaatcg tttttgtaaa tgagtttaaa ggcagcggca atttagaggg
    17401 ctctaccatc gccgccatcc gcaacaacat aatagaagga ttgatagacg ctaaaaggct
    17461 catcgtaaaa gatttaaagt cggatgccca attccaagct gaaatgacta aaagagcagc
    17521 cgatgcctcc gtgtccgaag aggaatatgg cttcacggtc ttaaggaata tgaacgctcg
    17581 ttgggtaatt gcaggaacgg ttactcgtgt agaggctgtt agaaagaaaa atagtgatgg
    17641 caaatatttc tatgatgccg ctatcgatgt atctgcaaat atcattgacg tagcaaccgg
    17701 aacaatcacg gaaaccaaga caatcacgac tgatggcggt ggactgttaa gtggattcac
    17761 agaagggaca acaattggag ataccgataa cgaagctata gccagtgctt gtctagttct
    17821 taaatctagg gctaaagctt tcgttgaaga atttttcact ttaaaaggag caatcctaga
    17881 agtagcctcc gagaaaaaag gaaaagcgga ggaggtatac atcagtttag gagaaacgag
    17941 tggtgtgaag aaaggagata ttttcgaagt tttcgagcaa agagtgatcg taggaagaaa
    18001 aagcaggaag aaaataggag aactgaaagt taaaacagtt gaaggtgatg atatctcatt
    18061 atgtaatgtc accaaagaag ggaaagtcat ttttgagaaa atacaagctc ttgaagaaaa
    18121 tcaatcacta tccatcgaat cccgtccaaa aactcaaaac gtactcttct aacatatagt
    18181 tctaattatg ggtcgccatt gtgtgaccca taacttctat agattaaaaa cagtctgaga
    18241 tatgcgaaac aaattcatcc tttatctata tagctatatt ataggaatcg gcctaattat
    18301 tcctaatacg atattggggc aatccagtga aaatttcacg aacgacgcaa ccttggtatc
    18361 tgaccaaggg agaaccgcta tcatcctttc gtccggtatc cacgagaaga aaaaagaggc
    18421 tgtagccatg gctatactat cagccttcga cacttatttc ttttccggca ttgcaggact
    18481 aaatgaggat atgcccctca ttggagagtt agagacccaa gaacagaaag attatgtaaa
    18541 acgcatattt aaggaaaacc gatacactca atttatcggt ctagtaaccg aagtcaacgg
    18601 ctcccctgaa aaaatgccca caagacaatt taaggcaacc atacaattcg aattaaaaac
    18661 agatgcctta tataaagaca tgcttcgttc caaagtcata aaaaaggatt tggaaagaat
    18721 gaacacgacc gagatccgcc aagagatacc tcaattcacg ttaaccgtgg ttcctttcaa
    18781 accggaagga accacctata gcaacatatt aaaaaatgat tatgaaatac gaaatgcgat
    18841 cacacgtatc gaggcgatgc taaaaaccaa gaaatatgag gttaaagatt tcctagcggt
    18901 agtggcttcc gtagaaagag acctgcaatt cgagatggac aagacagtca tgtcaaacga
    18961 taaacagctt atcaatcaaa cccaagctga cgtatatatc acggtcgacc tagcgaataa
    19021 caggagaccg gatggcggta tgggagtcgt aaacctaaaa gcttatgagg tatcaaccgg
    19081 caacttgctc agctctgccg aagggaaatc aaaacgttac agagattaca taatcgcaaa
    19141 tctttacgac agagccctag agaattgctt agatggtttc atccagcagc ttaccagcaa
    19201 ttgggcaagc aagatcacgg atgggaacca atatgccatc aatttctcca tcgccccgga
    19261 atcggccatc gatatgagca ccgaagtagg cagcatgggt tttccactag ccgacgtatt
    19321 aaccctatgg ataaaaatgc atgcctttaa cgggaaatac catctggctg gtagtgtaga
    19381 tgaatatatc aagtttgacc aagttcagat acagcaaggg caagagcaag aattcatctt
    19441 aagtttgtat acctatttgc gtgatgagtt aggcattagt tgcaatcgta ggcaaagcgg
    19501 taaaacctat tatataacga tacaataaac atatgagata cattatagca ctgatcagtt
    19561 ggctacttat aagcagcctg tcaatcacta tacatgcgga gaaaaagccg gactggttgg
    19621 cagaacgccc caacgggacc ttcttttata tcggtatagg aagcgcctcg aagtcttctc
    19681 ccaattacca acaagtagcg aaacaaaacg cgatagccga gcttgtctcc gagatcgaga
    19741 tcaaagtaga ggctaactcc ttaatgacga ccttggaaaa ggaggacgaa tctgtatcct
    19801 cctacttctc ggagatcatc cagacatccg tgaaacaaca tatcaagaat ttcgagcaag
    19861 tggacaactg gcaagacgaa caaaattatt gggtctatta ccgcctcgac aaagagacat
    19921 acgccgagca agtacagaag cgcagggaac tagcgatccg gcaaggattc gatttttggt
    19981 ataacgggga gaacaccttg cggcaaggtg atctattgac cgctatagac ttgttcatgc
    20041 agggcttgac cgctatcgaa ccctgcgtta acgaggatct aagctgctct tatgaaggac
    20101 agaccatttt agtaggcaac gccctataca cctcactgca aagcgtgttc gatggtatcc
    20161 agctaaaacc gtccaactcg gaaatccaag cgagcgcatt tcaagcctcc cgtaccccga
    20221 tcatactaac catacacaaa aacaatattc cattaagaaa tttacccatc aaaggagaat
    20281 tcaactccgg cggaggctca ttatcggaga tcatcccaac ggatgacaat ggggaaacaa
    20341 ctgtttacct acagaatatc acttcaaaga acacgaacca agagattctt tttacgctgg
    20401 acatacaccc attcacgcag atcaagaacc ctctgttcaa caccctaaaa caacagttat
    20461 cagccaatac gcccagatgc caagtgttgg taagtagcga ttcggagaag aacatccgtg
    20521 cgtatatcca atccaagcaa caaggaaatg aaggtcttgt cagaggaata cataatctac
    20581 tgacgaataa ttactttgac atcaccgact cccagaacaa agcggatgtc cttatactca
    20641 tccaaagtga tttctcacaa gggaatatcg tggaaggaga tatatacaac atgaaagaat
    20701 atttcaccac gataagtata caaatcaaaa ataaccgcag tggcgctatc ttgttaaatt
    20761 acctattgga aaaaaagagg actttatctc ccgcaaatac atctattgcg aacgcacgta
    20821 attctgctat tcgagaagcc atgaaaataa ttaacagaga actaggcaag caattgaaag
    20881 acgtaaaaat agatacgaac ggggaaatcc ctcaagtaaa tgatacacca aaggccccta
    20941 agcgaccgag ccatgtaagc accccgccca accaacctgt catcgtgata catcctaaac
    21001 ccacgagcca gacaccggtg gagaaacctc aatctacggt ctcccctact cttgccaaga
    21061 aaaaagcaga agcggagttg gagccgggga tatttataag ttataatgga aaaaaagaga
    21121 tgaacgaccg tacgttcctc aagttcagca tagagaacaa gaatcaagaa gattacaagc
    21181 taggcctgta taaccgtgag ctgctcatcg tcaatggaaa tggggaggaa atgaaatgta
    21241 tcaccgtgaa aattggttcc aaatcagata gctatgacat acaagctacc attgtaccca
    21301 acacccctac tttattggaa gtagagataa tgaagacggg aaagatcgct cttttccagc
    21361 tcacgaatac gaatcgtcga acaatcaaac tcaggaactt agaatagcaa taagggtgga
    21421 ggccgaaaaa cccaatgata gagtaggctt ttaattaaaa aagaataaaa atgaaacgat
    21481 taaattatgt aatgggaatg gcgatgggga tcgtcttttt attaaccgca tgtggaggtc
    21541 ctaaaagcgt agcgcaacaa gatgtcgccg tgatcgtacc ttgctccggg cctgaataca
    21601 tgaccaatag ccaatatata cgggctagcg ccatggggtt atctacggat atgactatcg
    21661 ccaaaaagaa agcgcagtca tctgcccgta cggaaatagc taccgctatc gaggccaagg
    21721 taaaagccat ggtagaagac tatacatctt cttatcaaaa tggtgaaaat gatgagagta
    21781 aaagaaggtt tcaagacatc gcacgaacga ccgtactgca gaagctaaat gggttaagaa
    21841 cgatttgcga acaaaccatg aaaactccgg ataataaata taaggtgtat atcgcactag
    21901 agctagccgg caacgaactt ttggaaggaa tcagtaattc catcaagaat gatgacaaac
    21961 ttcgaattga cttcgagtac gagaaattca aaaaagtatt cgaggaagag atgagcaagg
    22021 aaaattaaag ttactatgtt taactaactg ttccacccgt cccctctcac ctcttcagcg
    22081 aagtaagggg gacggccaaa cagtttacca atcacctaaa gacgaagaat gagcaaacgg
    22141 cttatacatt tagtcctttt cctgtcaggg ttctcagccc tatttgccca agataatgag
    22201 aactatacgc aatcgtatca ttgggctagt gggtatttgg aaaatatccc acatgatttt
    22261 ccattggctt tacgagatga ggaaaccatg ggtacttcag atcccggact atgcccggaa
    22321 atcgcccggg aacaagccat acagcgggcc ttattcctgt attcgctaaa gcgaggctca
    22381 cgcatgagca tgctgacaga ctatttcatc ataaatcaag tcgccaccaa tatgaatgat
    22441 tacaaacacg agaaaatgat ggtcatggcg acactacatt ccgagcctca gacctattcc
    22501 ttttccgtca tccgagaaca cacctcaata tatggggaac agttcgtctg gctcaccgta
    22561 aatagccaag gcaaggagca acgtacgctc tcttcttttt atgaattcat gctcagtacc
    22621 agcaaggaat cccatgaacg acaagaacaa agactatctc tttcgatacg ctgctacaat
    22681 gactcgatcc tcaaaaatca ttcattcact ctcaaaggga acaaagaaaa gctaatcatc
    22741 tccacacaaa tcaatgacct cttgcttcct cttccgaccg atctatatct atacaaggat
    22801 aaaggaacgc agctggcaca agaaaaaaaa gaatatcctc tttcaagcgg atattggagt
    22861 accctgctgg aatcactaag cgatgccctc actaactttg actttccggg agtaaccatc
    22921 caagaagttt ttgagagtta tcaagatacg aaccaacagt tatacagaga aaagacctgt
    22981 tgttccttat ctgccagacc agtcatcttg agtatactga acaaccatat tttcttggat
    23041 tggtcgattc agacgatcca ataaactaaa tttcctatac catgagaaaa gctctattga
    23101 tactaatttg cattcatacc tttattccta tagggaaact gtatgcacaa gatccatatg
    23161 cggaatataa ggaattcata aagaaacaaa ggcaagaata taatgatttc cgcagaaagg
    23221 aaaatcagga attcgcctcc ttcctaaaaa actattggaa accctataca aaagaagaag
    23281 ctcttaaggc acctacccga cctgagcccg taaacccggt tgtctatacc gaccctttgc
    23341 gagaacccga gcaaagacct agtgtatcaa ctgttcctcc ccggaaaatc aatccggaag
    23401 ataagcctcg tcctatacgg ccaatttccg atgagaatcc acagcctcaa gaagatgata
    23461 agcttttcag actcgccttt tatggaagat ccttacactt atcgaagata ttggatacgc
    23521 cattccgctt gaccggcatc acggaaaacg agatatccca agcatggagc agactaagcg
    23581 aaacccctta caaaacgctg atagacgatt gcttgcgtat ccggaaagaa tcacatcttt
    23641 gtgattgggc ctatttccta ttaaccaaca agatcgccca acatttttgc ggagaaaacg
    23701 caaagaacga gatagcgttc atgcagatgt tcctactttg ccaatccggc tataaagtaa
    23761 aaaacggacg taccgaaaac caactactcc ttatgatctc cacggattgc attgtttacg
    23821 gctttcctta tcttacaata gataatgaga aatactttat tatcaatacc ccgaaactca
    23881 gccaacaaga gatttatacc tataagaaag atttctctgc ttccacgcag actattcaca
    23941 tgcatattca agataaacaa acatggagct caaccctctt cagccgtaca ttggaagcca
    24001 aaagatatcc ggtgaaagta accgttaacc taaatcaaga tcttattgac ttctataagg
    24061 aatatcctca atgcgaattc acggtctatg cctgcgctct cgtaagcgat gaggtagcca
    24121 gctcaatatt acccccatta caagatgcga tccaagggaa aaccgagaca gacgccgcta
    24181 atatcttact gaattttgtc caaacggcat tcctctatca aactgatcat gaacagttcg
    24241 gatacgaaaa gccattcttc gtagaagaaa cattttatta tccctattgc gattgtgaag
    24301 accgggctgt tctttatgcc tatttggtaa aagagctatt aggactagat atcgtactgc
    24361 tcaattaccc acagcacttg gccacagcgg tccttttcaa cgaaccgata aatggcgact
    24421 tcgtgaacgt ttccggaaaa agatatacgg tttgcgatcc cacctatatc aatgcgccaa
    24481 tcggaaaggc gatgccacaa tttaaagacg caaaagtaaa agtaatatcg aatata
//
