LOCUS       c00049_gnlPro..        16801 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENMPDONF_67.
ACCESSION   c00049_gnlPro..
VERSION     c00049_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:15:15
            Original ID  :: gnl|Prokka|ENMPDONF_67
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16801
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16801
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3825:6801]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3826..6801
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16801
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16801
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(78..3503)
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="LSNNAIICMHQDPDGYLWIGTYDGLNLYNGKDTYVYRFKLNNKNS
                     LCSNIIHKISDAEPGFLWISTSLGINKFSLKERKVTESFPGYMECDLLASDSSGITLAI
                     CKENRISCYTPSSDGFRDLPREGVGPQTVRTLFAGTDGHFYLLLASGILKKLTPDFSDT
                     TFNLLSEERQFHNKPILSAFYENNHIFIVDTDNKLYRQHVDGKGKEFLFDLPEMTKQYG
                     NIIKICTFQSNVYIVFRNGNILDLSQPENTINMGIGIFCLMNDKRQEILWLGTDGQGIR
                     MFYDKPDLFGSILLKDLPINIQNPIRSLYTDDDQSLWLGTKGDGIVRIQAYDTYHNKKM
                     IPQSAITHFTTADGLSSNRVYCFQKSEYHPCIWIGTEGPGLTYYSYKEKRIKTIPQRED
                     TTPLRYVHSICEVDDSTLWLATTGNGLQKVTLHIDKAVPTIGKVQTFPLKNGKNICKEI
                     QSMVYDNDSTLFLGSRGGYGVIRFNIFNQGYEFLQTNNLRNPAIGDVLSVCQTEDSTFY
                     AGASSGLTRIKFRGGKMRLRQFDKSDGIVNDMIHGIHEGNDSCIWLSTNKGLTKYNPRN
                     NFFHNYHQPYFSVTEFSDDAYWKCPYSERLFFGGINGLVWVNKQTEPEHTYQPELSFFE
                     LQMDKQILPLYKDISRNGVTVPADVQSLTIAFVAPDYINGENYEYSYQLVNYNSSWEKL
                     QKTNKVTFMNLPYGEYLLKVRYRNDVIDSSAKEYTLPIKVLPPIYLSSLAIFTYLFIGT
                     VLLIIATYRIHHQILKKQKQIADKIKEEQKEKLYESKLNFFTHITHELCTPLTLINGVE
                     NYIQAYAATSKDKTLEKYTSVLRENVEELNGLIQEILDFRKAEDAGFSHTHIRRVSVSS
                     LLRTQFEWFYPLSEQHQIQFKIDAPKELYWNTDSVYFKKILANLISNAFKYTEDGGTVR
                     ISLHEEENFLVLKVYNTGKGIEEADMQNIFDRYRILGTMDNDDNRQNTTRNGLGLFICH
                     SLVQSLGGKIDIESEVGQYAEFTVTLPFGTVEETSDNTIDEEIPVSLPSPNTDIQEPQI
                     SHTEQKETEDKPMILVIDDHKDIVWLITETLSSEYQVQEAYNAEKALEFLKQYTPSLII
                     TDIMMPNMDGLELISLIKETLIPQHFDLTLFISS"
     CDS             3826..6066
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_2"
                     /sec_met_domain="Gly_radical (E-value: 9.3e-46, bitscore:
                     145.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1e-281, bitscore:
                     926.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENECWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRKVWNKLTEMFKVEREKGVYDAETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFEKMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIHEGKLTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRG
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFM
                     EYLRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGA
                     IAALASVAKLPFQHAHDGISYTFAVSPATLGKEREVQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             6067..6801
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 67.6;
                     E-value: 4.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_3"
                     /sec_met_domain="Radical_SAM (E-value: 3.1e-33, bitscore:
                     106.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNPK
                     GKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             6928..7578
                     /locus_tag="ctg49_4"
                     /transl_table=11
                     /translation="LLYATNIYFCKEIKNDIDQKMMNSMKTPQEIAEMISKRFYPLPDA
                     DLDSLASIIESSKAAKGKLLLDNGQISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNI
                     VICIASTFQREPTRLLIEALEPTVYHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQ
                     EKADSWRFESARKRYLRFQQEYPEAAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             7776..8966
                     /locus_tag="ctg49_5"
                     /transl_table=11
                     /translation="MGRASVPSGASTGENEALELRDGDKKRYGGKGVLKAVENINTIIA
                     PALKGMSALDQIGIDHAMLALDGTKTKSKLGANAILGVSLAVAKAAANYLDIPLYRYIG
                     GTNTYVMPVPMMNIINGGSHSDAPIAFQEFMIRPVGAASFKEGLRMGAEVFHALKKVLH
                     DRGLSTAVGDEGGFAPNLEGTEDALNSIIVAIKAAGYEPGKDVMIGMDCASSEFYKDGI
                     YDYTKFEGEKGVKRTSDEQVDYLEKLINEYPIDSIEDGMSENDWAGWKKLTDRIGNHCQ
                     LVGDDLFVTNVEFLSRGIKEGCGNSILIKVNQIGSLTETLNAIEMAHRHGYTTVTSHRS
                     GETEDATIADIAVATNSGQIKTGSLSRSDRMAKYNQLLRIEEELGDRAVYGYKRIN"
     CDS             9187..9753
                     /locus_tag="ctg49_6"
                     /transl_table=11
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFT
                     FVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHD
                     GEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             9773..11326
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_7"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.7e-48, bitscore:
                     154.5, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLESTLKEQLKGIFAGLNANYTFDISISPAHESRQELLDLLGDVA
                     SCSDKMSMRVSDGDGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNFPD
                     ESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQAEVD
                     ALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVGGGPA
                     GASAAIYSARKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHMRQYPI
                     DLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIIATGASWRKLNVPGEAEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDGLKADQVLQEKAKSL
                     PNVEIFVSSQTTEVVGNGDKVTGIRTKDRKTGEERVIHLDGIFVQIGLAANSGVFREIV
                     ETNRPGEIVIDAHCRTNVPGIYAAGDVSTVPFKQIIISMGEGAKAALSAFEDRVRGVLG
                     "
     CDS             11809..14118
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MNKFFIFILCLCCALTVAQATGEDRLNDSDANVFGHVLDKKTGEH
                     LPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTLEYKALGYKTISKEVTLKKGKTLEI
                     NVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVR
                     VETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGG
                     GSALFGSSAIAGTINIITKEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAG
                     LYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKTSTYSKLTFEYHHMNEYRRGG
                     NLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDP
                     NAYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHI
                     ESAFLQNEWKNKRWSFLIGGRLDKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRA
                     PQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHRFKNGIQLNFLVEGFYT
                     SLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRY
                     KEAEKWSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYI
                     PLDKAVETPDFFDMNIKLAYEFPLYKELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIY
                     GPASPRSYFAGVKMSF"
     CDS             complement(14292..15137)
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="LQTYSLGQELLQDMPNGLNRLAKAGYTDLEIFGYREDTGKFGDYN
                     PKNTTFIASKDYKKMVDDAGLRISSSHLTPSLREYTKENMPKFDEFWKKATDIHAELGV
                     SCMVQPSLPRIENEDDAKVVSEIFNRAGEITKKAGILWGYHNHSNEFKRVLKAGEKPEQ
                     NPNPWAPPKGTYIEELFLKNTDPDKVMFELDVYWAVMGQQDPVEWMENYPNRFKLLHIK
                     DRWIIGDSGMMNFPNIFKKAYEIGILGYYVELEGDKKGRTQFEGVEKSAAYLQAAPFVK
                     "
ORIGIN
        1 ttacgcttgt tttgatttgc aacactaaga taagtgaaaa atctgacatg gcaaaatcct
       61 gagcaacttt ttgttgctca ggaacttata aataaagtta aatcaaagtg ttgcggaatt
      121 aaggtttctt tgataagcga gatcaattcc aatccgtcca tattaggcat catgatatcg
      181 gtgatgataa gggacggagt gtattgtttg aggaattcca gagccttttc cgcattataa
      241 gcttcttgaa cctgatattc ggaagagagg gtttccgtga ttaaccagac gatgtcttta
      301 tgatcgtcga taacgagtat catcggttta tcttccgtct ctttttgttc cgtatgtgag
      361 atttgcggct cttgtatatc cgtgtttggg gaaggaagcg atacgggaat ctcttcgtct
      421 atcgtgttgt ctgaggtctc ctctacggtg ccaaaaggta aggtaactgt aaattcagca
      481 tattggccga cctcgctctc tatgtcgatt ttaccgccta acgattgtac gagactgtgg
      541 cagataaata agccgaggcc gttccgtgtc gtattttgcc tgttatcatc gttatccatc
      601 gtaccaagga tacgatatcg gtcgaaaata ttttgcatgt ctgcctcctc gattcctttg
      661 ccggtgttgt aaactttaag gacgaggaag ttctcctcct catgtaagga gatacgaacc
      721 gtgcccccgt cttccgtata cttaaatgcg ttagaaatca gatttgctag gatcttcttg
      781 aaatagacgg aatccgtatt ccaataaagc tctttgggag catcgatctt gaattggatt
      841 tggtgttgct cggatagtgg gtaaaaccat tcgaattgag ttcgcaaaag agaggatacg
      901 gatactctcc ggatgtgcgt atgactgaat cctgcgtctt ctgctttccg gaaatcaagg
      961 atttcttgga taagtccgtt cagttcctct acattttccc ggaggactga agtgtatttt
     1021 tctaatgtct tgtcttttga ggtggcggca taggcttgga tataattctc cacgccattg
     1081 atcaaggtaa gcggggtgca tagctcatgc gtaatgtggg taaagaaatt cagcttggac
     1141 tcgtatagct tctctttttg ctcctccttg atcttgtctg cgatctgctt ctgtttcttt
     1201 agtatttggt gatggatacg ataggtggcg atgatgagca aaaccgtacc gataaaaaga
     1261 tacgtgaaaa tggctaacga gcttagataa ataggaggta ataccttgat aggtagagtg
     1321 tattcttttg ctgacgaatc aatgacatca ttgcgataac ggactttcag caaatattcc
     1381 ccgtacggta ggttcatgaa agttaccttg tttgtctttt gcaatttttc ccaagaggaa
     1441 ttatagttga ccaactgata cgaatactcg taattctccc cgttgatgta atccggagcg
     1501 acgaacgcaa tcgttaacga ttgcacatca gccggaaccg ttacaccgtt ccggctgatg
     1561 tccttatata atggaaggat ttgtttatcc atttgcaatt cgaagaaact taattcgggt
     1621 tgataggtat gctccggctc cgtttgttta tttacccaga ctaatccgtt gatgcctcca
     1681 aagaataaac gctcggagta tgggcatttc caataagcgt catcagaaaa ttccgtgacg
     1741 ctaaagtaag gctgatgata attatggaaa aagttgttcc ggggattata tttggtgaga
     1801 cctttattgg tactaagcca gatacagcta tcgttcccct catggatacc atggatcatg
     1861 tcgtttacga tcccgtcgct tttatcgaat tggcgtaaac gcatctttcc ccctctgaat
     1921 ttaatccggg tgagaccgga gctggcgcct gcataaaacg tggaatcttc ggtctggcat
     1981 acggaaagca cgtctccaat ggccgggttt cttaaattgt tggtttgcag gaattcatat
     2041 ccttgattga aaatattgaa acgaatgact ccgtaaccgc cacggctccc gaggaacagg
     2101 gtcgagtcgt tgtcatatac catcgattgg atttctttac agatgttctt tccgtttttt
     2161 aacgggaagg tttgtacctt cccgattgta ggtacggctt tatctatatg taaggtaacc
     2221 ttttgcaatc cgttacccgt tgtcgctagc cataatgtgg aatcatctac ctcgcaaata
     2281 gagtggacat agcgtagagg ggtggtgtct tctcgttgcg gtatcgtttt tattcgtttc
     2341 tctttatacg aataataggt cagtcccggg ccttccgtgc caatccagat acatggatgg
     2401 tactcgcttt tttggaagca atacacacgg ttgctggata ggccgtcggc ggtggtaaaa
     2461 tgcgtgatag cgctttgtgg gatcatcttt ttgttatggt aagtgtcata cgcttgtatc
     2521 cggacaatac cgtctccttt tgtcccgagc caaagggatt gatcatcgtc tgtatataaa
     2581 gaacgtatgg ggttctgtat attaatcggt aaatccttga gtaagataga gccgaaaaga
     2641 tcgggtttgt cataaaacat ccgtatacct tgcccgtctg ttcccaacca gagaatctcc
     2701 tgccttttat cgttcattag gcaaaagata ccgatgccca tatttatcgt gttttccggt
     2761 tggcttaggt ctagaatatt gccgttacgg aaaacgatat acacattgga ttggaaggtg
     2821 catatcttga tgatgttacc atattgtttt gtcatttcag gcagatcgaa caggaattct
     2881 ttcccctttc cgtctacatg ctgtcgatat aatttattgt cggtatctac aatgaaaata
     2941 tgattattct cgtaaaatgc ggataagatc ggtttattat ggaattggcg ttcttccgat
     3001 agcaaattaa aagtagtatc ggagaaatcc ggagtcaact ttttcagtat gcccgaggct
     3061 aataataaat aaaaatgtcc gtccgtcccg gcgaataagg tacgtacggt ttgagggcct
     3121 actccttctc tcggcaggtc ccggaaccca tcgctagatg gggtgtagca agagatcctg
     3181 ttttccttac aaatagcgag cgtgatgccg gatgaatcgg aggctaatag atcgcattcc
     3241 atgtatccgg ggaaagactc ggtgactttc cgttctttta gtgagaattt attgatacct
     3301 aaagaggttg atatccataa aaagccgggt tctgcgtcgg atattttgtg aatgatatta
     3361 ctacaaagag agtttttgtt atttaatttg aaacgatata catacgtatc ttttccgttg
     3421 tataagttaa gtccgtcgta agtcccgatc cacaaatagc catccggatc ttgatgcatg
     3481 caaataatgg cattgttcga caaattaatc atatttgcct tatgcaaaga tttagacgcg
     3541 agtgagatag gagatgcgat taaagatagt attcctataa ataaaacggt aaacaggata
     3601 tttctcatgt gtttgatcca gattaacttt tacgttctgt aggcaaagat agtgaataaa
     3661 atggagactt cgtgcaaagc atcgcattac tatcccgttt cttcttgtat atttttaata
     3721 cctatttata gggattttag aggggtgtcg caaatgttac aggaacatga ggataaaagt
     3781 tttacctttg cggcggtaaa aatgtggtat tagataagat tgtttatgaa atttgagaat
     3841 gagtgctggg atcactttaa gggtgagacc tggaaaagag agatcaatgt aagagatttt
     3901 atccagagta actatacgcc ttatgaaggg gatgattcct ttttagtcgc ttcttccgag
     3961 aagacccgta aggtctggaa caagctgacc gagatgttta aggtcgagag ggaaaaggga
     4021 gtttatgacg ccgagacaaa attacctcaa gggatcgatg tatatggccc gggctatatt
     4081 gataaggaga atgaggttat cgttgggtta caaaccgatg ctccgctgaa acgtggtatc
     4141 ttcccgaagg gcggtatccg tatggtcgag aatagcttgg aagcttatgg ttatcatttg
     4201 gacccgatga cgaaagagat cttcacgaag taccgtaaaa ctcataacga gggcgttttc
     4261 tccgcatata cggaagagat gattgccgca cgtcgttcgg ctattatcac cggtctgccc
     4321 gacgcgtatg gtagaggacg tattattggt gactatcgtc gtgtcgcttt atatggtacg
     4381 gcaatcttga tcgaggagaa aaagcgtttc ttgaatcgtt tggatatcca agagatcacg
     4441 gaagagatca tccagagccg tgaggagatt tccgaacaga tcaaggcttt gaaagcgttc
     4501 gagaaaatgt gcgctagcta tggctttgat gtgacccgcc cggcacaaaa cgctcgtgag
     4561 gcggttcagt ttgtgtactt ggcttatctg gcggcggtaa aagaccaaga tggcgcggcg
     4621 atgtctatcg gacgtacttc tacgtttttg gatatttata tcgagaaaga catccatgag
     4681 ggtaagttga ccgaagagga ggcgcaagaa ttggtagacc agctgatcat caagttgcgt
     4741 atcgttcgtt tcttacgtac gccggaatac aatgatttgt tctccggtga tccggtttgg
     4801 gtaacagagt ccttgggcgg ccaaggagtg gatggccgtt ctttggtaac aagaacttcc
     4861 tatcgttatc tccatacatt atataatcta ggtccggcac cggaacccaa tttgacggtt
     4921 ctgtggttta agaacgctcc cgagaactgg aaacgtttct gtgccaaggt ctctatcgat
     4981 acgtcggcta tccaatatga gaacgacgat ttgatgcgtc cggattatgg agatgattat
     5041 ggtatcgctt gttgcgtttc tcctatgaag atcggtaagc agatgcagtt cttcggagcc
     5101 cgtgcgaatt tggcgaaatg tttattatat gcgatcaacg gaggacggga tgagcgcagc
     5161 ggcgtacagg tagccccgat gttcgagccg gttcgcggcg agtatctgga atacgatgag
     5221 gtgatggcta agtatgagca aatgatgcgc tggttggcga aagtgtatgt gaacgccttg
     5281 aagataatcc attatatgca tgataaatac gcgtatgagg cattcgagat gtcgcttcac
     5341 gatggggatg tagagcgtat ccgtgcgaca ggtatcgccg gtctttctat cgttgccgat
     5401 tcgttggctg ctatccgtga tacgaaagta cgtgtgatcc gtgacgagcg tggcttggcg
     5461 gttgatttcg aacgtgaggg cgaatatgtt cctttcggta ataacgatga tcgtacggat
     5521 agtatcgctg tagagatcac cgagaagttc atggaatatt tgcgtcagca cgagacctat
     5581 cgccatgcga aacctacgca gtccatcctt acgatcacct ctaatgtggt atatggtaag
     5641 aagactggta cgacaccgga tggccgtatc ggtggaactc ctttcgctcc gggcgcgaac
     5701 cctatgaacg gtcgtgatac gaaaggtgct atcgctgcgc tagcttcggt agcgaagctt
     5761 ccattccagc atgcgcacga cggtatctct tatactttcg ctgtttctcc ggctacgttg
     5821 ggaaaggagc gtgaagtgca gatcaataat ctggttagct tattggatgg ctattttact
     5881 ccggatggag gtcagcatct gaatgttaac gtatttgata aggatttgtt gatcgacgct
     5941 atggagcatc ccgagaaata tccgcaactt acgatccgtg tatccggata tgcggtaaac
     6001 ttcgtgaaac tgactcgtga acaacagttg gatgttattt caagaaccat taaccattca
     6061 ctgtaagtga taaaaggtaa gatacattca ttagagagtt tcgggaccgt agatggtccc
     6121 ggaattcgct ttgtcgtttt tatgcagggc tgcccgttgc gttgtctgta ttgccataac
     6181 ccggatactt ggaacccgaa agggaaggtg aaatatcaga tgactcccgg cgagctattg
     6241 acggaagtct tacggtataa gagttttatc gcccgtgggg gggtgactgt taccggtggg
     6301 gaacctttat tgcaacctga gtttctgaaa gagtttttcc gtttgtgcca agagcaaggt
     6361 cttcacacag ctttggacac atctggtttc gtatgtacct caaaagcttg ggaagtcttg
     6421 gattatgcgg acttagtgtt attggacatc aaaaccttaa acccggattt acatccgtta
     6481 ctggcgggtg tcaagcagga taatacgctt ctgttcttgg atgaattgga gagacgtggc
     6541 atagatactt ggattcgcca tgttattgtc cccggatata cggataatga cgagtggctg
     6601 gaggcgttag ctcggtatgt cagttcatat aaagtggttc gcaaagtgga attattgcct
     6661 tatcatacga tgggaaccta taaatatgag caattaggcc tcgattatcc gttaaagggg
     6721 gtggaaccct tatcaaaaga acgtttagat aatgcgaaag cgatattctc tcgctacaaa
     6781 ccagaaaata acaaggcctg atctctcgat caagccttgc gattatgcaa cagctaatca
     6841 gggaaaacaa tctaatccga ttagctttta aacgatagta ataatttttt gcctagacta
     6901 accttgacta tttaatatgt gtttgttttg ttatatgcaa caaatatcta tttttgtaag
     6961 gagataaaaa atgatataga tcagaaaatg atgaatagta tgaagacacc acaagaaata
     7021 gccgaaatga tatccaaacg tttttatcca ttacccgatg cggatttgga ttctctggcc
     7081 tcgatcatag aatcaagtaa ggctgcgaaa ggaaaattat tgttggataa cggacaaata
     7141 tctaaatatt tatattatgt ggaatcggga ttattacgcc agttttacta taagaataaa
     7201 cgtgatatta ccgagcattt ctcctgtgag ggaaatatcg ttatttgtat agccagcaca
     7261 ttccaaagag aaccgacgcg tttattaatc gaggcattgg aaccgacggt ttatcaccgg
     7321 atctcttttt cggaatttag cgatttattg aaaacatctt tagctattaa tagattgtac
     7381 cagaaaatac tggagtgggc tttgatgctt tcgcaagaga aagcggactc ttggcgtttt
     7441 gagtcggcaa gaaaacgtta tctgcgtttt caacaggaat atccggaagc agcgaaacgt
     7501 gcttctgtca atcatatcgc ctcgtattta ttgatgacac ccgaatcttt gagccgggtg
     7561 cgggcgggag tgttgtagcc tctacctaca ttcaggtatt attgaggcga aaatagcaat
     7621 ttgtggtgat ttcacggttc tagtaatcca tctatatttg cgtcagttta aaaaacgtag
     7681 aagcaatgaa aatagaaaag attacaggac gtgagatcct agattcaaga ggtaacccga
     7741 cagtagaggt tgatatttta ctagagtccg gcgttatggg ccgtgcgtct gtgccttccg
     7801 gtgcgtccac cggcgagaac gaggctttgg agttgcgtga tggcgacaag aagcgttatg
     7861 gtggtaaagg cgtattgaaa gcggttgaga atatcaatac gattatcgct ccggcattga
     7921 aggggatgtc tgccttggat cagataggta tcgatcatgc gatgttggct ttggacggta
     7981 cgaaaactaa atcgaaacta ggtgcgaacg ctatccttgg cgtttcttta gctgtagcga
     8041 aagctgccgc aaattatttg gatattcctt tatatagata tattggtgga acgaatacct
     8101 acgtgatgcc tgttccgatg atgaatataa tcaatggcgg ttcgcatagc gacgctccga
     8161 tcgctttcca agagtttatg attcgtccgg taggtgccgc ttctttcaag gaaggcttac
     8221 gtatgggcgc tgaggtattc catgcgttga aaaaggtatt gcacgatcgt gggttaagta
     8281 ccgctgttgg tgatgagggt ggtttcgccc cgaatttgga aggtacggaa gatgccttga
     8341 actcaattat cgtcgctatc aaggcggctg gttatgaacc gggcaaggat gtgatgatcg
     8401 gtatggattg cgcttcttct gagttttata aggatggaat ctacgattac acgaagtttg
     8461 aaggagaaaa aggagtgaaa cgtacttccg acgaacaagt ggattatctg gaaaagctga
     8521 tcaacgaata cccgatcgat tccattgagg atggtatgag tgagaatgat tgggctggtt
     8581 ggaagaaact gacagatcgt atcggtaacc attgccaatt agtcggagat gatttgttcg
     8641 tgacaaatgt agagttcctt tcaaggggta ttaaagaagg ttgcggtaac tcaatcttga
     8701 tcaaggtaaa tcagatcggt tccttgacgg agacactgaa cgctatcgag atggctcacc
     8761 gccatggata cacgaccgtt acttcacacc gttccggtga gacggaagac gctacgatcg
     8821 ccgatatcgc tgtcgctacc aatagcggac agatcaagac gggatcatta agtcgttcgg
     8881 accgtatggc taaatataac cagctgcttc gtatcgagga ggaattggga gaccgtgccg
     8941 tatacggata caaaagaatc aattaagtat ataaagtaaa ttataatcgc taattatgta
     9001 gtaatccaaa acccaagata ttgaagggct tatccgtgag gataggccct ttttattgat
     9061 tgataaagta ttatctataa cctcataaaa tatatcgatt agaaaaattg ttttaatgaa
     9121 taaatatgtt atatttttgt atcggaaata aaaacaaata gtattcattt aaaaatagga
     9181 acaagtatgg aaccgattat taattctcaa cttccggagt ttaaagtaca agcttttcaa
     9241 aatggtaatt tcaagactgt aaccaacgag gacgtcttgg gtaagtgggc tatctttttc
     9301 ttctacccgg ccgattttac atttgtttgt ccaacagagt tggtcgatat ggctgagaag
     9361 tatgagcagt ttaaatcaat gggagtagaa atttactctg taagtacaga ctctcatttt
     9421 gtacataaag cttggcatga cgcttccgag actatccgta agatccaata tccgatgttg
     9481 gcggatccca ctggagcact gagtcgtgcg tttggtgtga tgattgagga agagggtatg
     9541 gcataccgtg gcactttctt ggtaaatccg gaaggaaaga tcaaagtggc cgagattcat
     9601 gataacaata tcggtcgtga cgcttccgag ttacttcgta aagttgaagc cgctcagttt
     9661 gtcgcttcac atgatggtga ggtttgtcct gctaaatgga agaaagggga ggctaccttg
     9721 aaacctagca ttgacttggt agggaaaatc taaataatta agagtataga tcgtgttaga
     9781 atcaacatta aaagaacaat taaaaggtat attcgcaggg ttaaatgcga attatacctt
     9841 tgatatatcg atctctcctg cgcatgaaag tagacaagaa ttgttggatt tattaggtga
     9901 tgttgcctct tgttcggata aaatgtctat gcgagtatct gatggggatg gattggaatt
     9961 cattttatta aaggatggag cgaaaacggg gattaagttt cgtggagtac ctaatggaca
    10021 cgagtttact tccttactgt tggcgatctt gaattcagat gggaaaggca agaattttcc
    10081 ggacgagagc atttgtaatc gtgttaaagc cttgaatggc ccgatacatc tgacgaccta
    10141 tgtctctttg acttgtacga attgcccgga tgtggtacag gcattaaacg ctatgacgac
    10201 tttaaatcct cagatccatc atgagatggt agatggggct atcaatcagg cggaagttga
    10261 tgccttgaag atacaaggcg tcccctctgt ctttgcggat ggaaaactga tccatgtagg
    10321 acgtggggaa ttcggtgaat tgttatcgaa gctggaagct cagtatggaa tcaatgagag
    10381 cctaacggag aagacggtaa aacgatatga cgtggttgtg gtcggtgggg gtccggctgg
    10441 tgcttctgcc gctatttatt ccgcacgaaa ggggctgagt gtcgctgtcg tggcggagcg
    10501 tatcggcggg caggtgaagg agacggtagg aattgagaat ctgatttcag ttccggagac
    10561 aacaggtacc cagttggctg acaatctgcg cttgcatatg cggcaatatc cgattgacct
    10621 gctggagcat cgtcgtatag agaaggtaac gatagaagga aacgagaagg ttttgtctac
    10681 ggctggaggt gagatattca aggctccggc ggttattatc gctacgggcg ctagctggcg
    10741 taaattgaat gtaccgggtg aggcagagta tatagggcgt ggagtggctt tttgtcctca
    10801 ttgcgacggt ccgttttata agggaaaaca tgtcgccgtg gttggcggtg gaaattccgg
    10861 tatcgaggcg gctattgatt tggcggggat ctgttcgaaa gtaaccgttt tggagtttat
    10921 ggatgggtta aaagcggatc aagtcttgca agagaaagcg aagagtttgc cgaatgtcga
    10981 gatctttgtt agttcacaaa caaccgaggt ggttggaaat ggcgacaagg taaccggtat
    11041 ccgtacaaag gatcgtaaga caggggaaga gcgtgttatt catttagacg gtatttttgt
    11101 tcaaatcggc ttagccgcta atagtggtgt ctttagggag attgtcgaaa caaatcgtcc
    11161 cggtgagatc gtgattgacg cacattgccg gacgaatgtc ccgggtattt atgcagcggg
    11221 cgacgtttcc accgtaccct ttaagcaaat cattatttct atgggagaag gcgccaaagc
    11281 ggccctttcg gcctttgaag atcgggtacg tggtgtactt ggttgaggaa agtacctaca
    11341 aataggtaat ttttgaacag cgtatctctt ttatcggtta tattactata tttgcggtcg
    11401 agagaaaaga gatggataga ttaagaaaat atctgaggat attactccct gcgctgttca
    11461 tagcctattt gggatgtatt attgcgttta cccacgttca tattgtcaac ggggtaacaa
    11521 tcgtccattc tcacccgtat cataaaacgg acgatggtcg tccggaccat gaacatggct
    11581 acgccgagtt tcagttgctt catcagttat ctgtcttgca gataacaggt gcggctttcg
    11641 tcgctattct gctggcggct ttttattcct ttatccgtaa cttatctttc gctccggtct
    11701 atccggacta tatcgttccc ttccggggaa gacgtacgct tcgtgctcct cccatattct
    11761 gatattgtga gattaataac attgtattac ttatcagaat aaattaaaat gaataaattt
    11821 ttcatcttta tactatgcct gtgctgtgcc ctaacggtag ctcaggccac gggagaggac
    11881 cgtctaaacg actcagacgc aaatgttttc ggacatgtat tggataagaa aacaggggaa
    11941 catcttccct ttatcaacgt gttgttaaaa ggtaccacga tcggtacgac caccgataac
    12001 tcgggacatt atttcctgaa gaatctgccg gaaggtaaat ttacgctaga atataaagcg
    12061 ctcgggtata agactatctc taaagaagtg accctaaaga aaggaaaaac cttagagatt
    12121 aatgtagaac tggaagaaga ccagatcgcc ttggatggcg tggtggtatc tgcgaatcgt
    12181 gcggaaactt cccgccggtt ggctcccaca ttagtgaatg tattggatgc gaaggttttt
    12241 actacgacca atgcggtgaa tttggcacag ggactaaatt tccaaccggg tgtacgggta
    12301 gagacgaatt gccagaattg cggtttccag caagtccgga tcaatggatt agacggacct
    12361 tatacccaaa tactgattga ttcacgtccc atattcagcg ctttatccgg cgtatatggg
    12421 cttgagcaaa taccggcgaa tatgatcgag cgggtagagg tgatgcgagg agggggatcg
    12481 gcactgttcg gctcgtccgc tatcgccggg acaattaata tcatcacgaa ggagcccttg
    12541 agaaattccg gggaattgtc gcatacgtta acctcgatcg gtgggacatc cgctttcgat
    12601 aataatacga ccctaaatgc ctctttggta tcggaaaatg ggaaagcggg cttatatctt
    12661 tttggccaga accgtcatcg ttccggtttt gatcaggatg gagatggttt tacggagttg
    12721 cctaaattga agaatcaaac ggttggtttc cgttcgtacc tgaaaacgag tacttatagt
    12781 aaattgacat tcgagtatca tcatatgaat gaataccgca ggggaggaaa tctgttggat
    12841 cgtccgcctc atgaagcgga tatcgccgaa cagttggagc attcgattga tggaggaggt
    12901 ctgaaattcg atcttttctc caaggattac aaacataaat ggagtgtttt cacttctgcc
    12961 cagaatacag accgggatag ttattacggg acgaaccaag atccgaacgc ttacggcaag
    13021 actacggacc tgacggttat ggccggtacg caatatgctt atagttttga taaattcttg
    13081 tttatgccat cggatttgac tgccggtttg gagtatagtt tcgatcattt gaaagacgag
    13141 atgatcgggt ataatcgctt tacgaatcag aaggtgcata tcgagagcgc atttttgcag
    13201 aatgagtgga aaaataagcg atggagcttc ttgattggcg gtcgtttgga taaacataat
    13261 atgatggatc atgtaatatt cagccctcgt gcgaatatcc gttttaaccc gacggaagat
    13321 atcaatatcc gggctagtta ttccagtggt ttccgtgccc cgcaagcgtt cgatgaggat
    13381 atgcatatct cggcggtcgg cggagaggtc gctatgatcc agcgtgcgaa agatttatcc
    13441 gaggagaaat cgcagagctt gagtgcttcg gtcgattttt accatcgttt taagaatggt
    13501 atccagttga acttcttggt ggaaggtttt tacaccagct taagtgatgt gtttgtcttg
    13561 gaagatattg ggaaagatga gcaaggcaat ctgattaagg aacgtcgtaa cggttccggg
    13621 gcgaaagtga tgggattaac cttggaagga aagtcggtgt taacttcatg gctatctttg
    13681 caagcgggcg ctactttcca gcgaagccgt tataaagagg ccgagaaatg gagcgatgac
    13741 gagaatgtgc cagccgagac aaagatgttc cgtacgccgg atatctatgg ttattttacg
    13801 gctactctca cgcctttcaa acgtttcacg gcttccctgt cgggaaccta tacgggaagt
    13861 atgttggtgc agcatttggc gggatatata cctttggata aggcggtgga gactccggat
    13921 ttctttgata tgaatatcaa gcttgcgtat gagttcccgc tttacaaaga gctgaaacta
    13981 gaagtaaatg ggggcgtgca gaatctgttc aacgcttacc aatccgactt tgaccaaggt
    14041 aagaaccggg attcctccta tatctatggc ccggctagcc cgagaagtta ttttgccggt
    14101 gtaaagatga gcttttaatc atgtaatgcc ctttgaaaaa acatgtacgt gtttcgtgaa
    14161 aaacacgtac gtgtttccga aaaaagacgt acgtgttttt ttgaaggcaa aataaataaa
    14221 aagacagtgt tcccaagcgt atgatcgccc tacggaaaca ctgtcttttt tatgggataa
    14281 atcgggatgt tttatttaac gaacggagcg gcttgcaaat aggcggcgct cttctctacg
    14341 ccctcgaact gggtacggcc ttttttgtca ccttccagtt ccacgtagta gccgaggata
    14401 ccgatctcgt acgctttttt gaatatattc gggaaattca tcataccgga atcaccgatg
    14461 atccaacgat ccttgatgtg caataactta aaacgattcg gataattctc catccattcc
    14521 acgggatctt gctgccccat aacggcccaa tatacatcca actcgaacat aaccttatcc
    14581 ggatcggtat tttttaggaa taactcctcg atataagtac ctttaggagg tgcccacgga
    14641 ttcgggttct gttccggttt ctcgccggct ttcaataccc gtttgaactc attgctatga
    14701 ttatggtaac cccataggat tccggctttc ttcgtgatct ctccggcacg gttgaagatc
    14761 tccgatacta ctttggcgtc atcctcgttt tcgatacggg gtaaactcgg ttgtaccata
    14821 caactaacac ctagctcggc atggatatcg gttgcctttt tccagaactc gtcgaatttg
    14881 ggcatattct ctttcgtgta ctcacgaaga gaaggggtta ggtgtgagct actgattctc
    14941 aaaccggcat catccaccat tttcttataa tccttggagg cgatgaatgt cgtattttta
    15001 ggattataat caccgaattt accagtgtct tccctatatc cgaaaatctc cagatcggta
    15061 tatcccgctt ttgccaatcg gttcaatccg ttaggcatat cttgcagtaa ctcctgtccg
    15121 agcgaatagg tttgcaaccc catctttttc ccggcggttg ccgaggatac cgcatccgtg
    15181 gcgggtatgg atctggtggg atttgaagcc attacttttt ggctggctat gccccctaaa
    15241 gtaagtaatg aaatgtttct caaaaatgtt cttctgtctg tcatggtgat aaagaattaa
    15301 aattaaacat ctgtttctcg caaatatagt taaccttttt gaagtttatt aagaaaatgt
    15361 ctctcaaaaa cttgcgattg ggtttaaata gatttaaaat ttgacataac tcaattttac
    15421 gaacttactc catacatcca attacctgaa taaggggatt gtttggtata cctccgtgga
    15481 tttttaatgt gattttaccc attcttaggt attgtggggc ggtagtctct gatcgtaact
    15541 ttgcaacgtt tttaaataac ataattgatt aaatgatgat gaagaaaatc agagggcttt
    15601 tcctctcctt tttactgttg cttatttcca tctcggcttt ttctcaacat aaaacaatga
    15661 tatcgggtaa agtcctgtcc acggaaaaaa caaccgtgga tttcgctacc gtttatctaa
    15721 aaggtacgaa ttacggcggg actacgaatg aggaaggtat ctatcatctt caagctcccg
    15781 caggagaata tacattagta gtatcggcta tcggatataa gacggtagag aaacccgtga
    15841 aactgatgcg tggggaacgg acaaagatga atgtggtaat cagccctcaa gctacggagt
    15901 tggatgaggt ggttgtcgtt tctaatggcg tgacccggct caagcgttct gcgttcaatg
    15961 ccgtggccct cgatacgaaa gccttgcaaa attcaaccca gaacttgagt gaagccttgg
    16021 ctcaagcgcc cggaatgaag atccgggaat ccggcggtgt cggctcggat atgcaactga
    16081 tgatggatgg atttaccggc aagcatatca agatctttat cgatggggtt ccgcaagaag
    16141 gtgtcggcag ttctttcgga ctgaataaca ttccggtgaa ttatgccgag cgtatagagg
    16201 tctataaggg tgtggtaccg gtgggcttcg ggacggacgc tatcggaggt gttatcaata
    16261 tcatcaccaa gaagaaccgg aacaaatggt tcttggatgc ttcttattca tacgggtctt
    16321 tcaatacgca taaatcttat gtgaacttcg gacagacttt ccggagcgga ctcacgtatg
    16381 agatcaacgt tttccagaat tattcggata ataattacta tgtggatact ccggtgaagg
    16441 actttacgac cggagcgatc aataagaaaa agatcgagca tgtgaagcgt tttcatgata
    16501 cgtatcataa cgaggccgtt atcgggaaaa tcggtttcgt ggataagaaa tgggcggatc
    16561 gtttgatgtt cgggtttacc tattcacata tgtataaaga tatacagacg ggcgtacgcc
    16621 aagaagtggt gtttggcggc aaatatcgga agggatactc gatcatgccg tcgttggact
    16681 atcgcaagcg tgatttcttc gttaggggct tggatgtggt attgacggcg aattataata
    16741 agaacatgac gaacaatgta gatacctctt cctatgaata taattggcgt ggcgagatgc
    16801 g
//
