LOCUS       c00089_gnlPro..        16572 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OILFAHPD_133.
ACCESSION   c00089_gnlPro..
VERSION     c00089_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:10:20
            Original ID  :: gnl|Prokka|OILFAHPD_133
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16572
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16572
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3132:6690](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3133..6690
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16572
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16572
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(560..1714)
                     /locus_tag="ctg89_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1894..3099
                     /locus_tag="ctg89_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3133..6690
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6815..7003
                     /locus_tag="ctg89_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7014..7874)
                     /locus_tag="ctg89_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7902..8732)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg89_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8729..9955)
                     /locus_tag="ctg89_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10428..11714
                     /locus_tag="ctg89_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RNFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHLRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11677..12009)
                     /locus_tag="ctg89_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12037..14790)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg89_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15123..16349)
                     /locus_tag="ctg89_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 agatattaaa gtatattgag taaactaatt cagttataac aaacgaagtt gtcaactaaa
       61 accagtacac atcattccat tgcttgaaac cagagtttca tcggtgtgaa actgtagttt
      121 catcggtgag aaactagagt ttcatacgct tgaaacttta gttccaaacg ctcgaaacta
      181 tctgaaacta ctgttgattt gattgactta accgcatgtt ccaatcacat tgaacgcatc
      241 agctacttca atagtactgc tctctctgaa aacattaaat catatatcag tcaataatac
      301 ataaattatc agtccttaat acttgatttc tcaattatta atatctgaga aatcaaacgt
      361 taacagttga gatatcagat attaacatcc tgtaaatcaa agaataacac agtaaaaaca
      421 gtatttatca ggacgatgca gagtgagagc aagtccttgc tctcactctg ctaccactgg
      481 atctctaaca gctaaaacat cgatgaataa agggatacag acgaactgtt agagcatgag
      541 agcaaaagca ctatcttttt cactggggga gagtaagcaa aagaaacgca cgataccggc
      601 tttgaggcgt caccggtact aacggcaaat atccggcaca cacccgatta ttctctacgg
      661 acaaagggaa cgaagccgac atctgccgat gttcctccaa agcctgaccg gctaaaggat
      721 aataatcaat ccgaaaaact ccttccgcat ccgcagccaa ataacgatcc gtcaagagcc
      781 atgccaccac ccccatattc attcgcagat taatttcgac acaaggatga atccggtaaa
      841 caggcgcttc atccggaaaa tgacaaatca tcatatccac tcccaagtat ccatgataaa
      901 agccaccgaa caaagctgac aattcttctt ccaaacgagt ccgcagcctg ataaattctt
      961 cttgtggcac ataagccgat agtttctgca gaatcttctc gtcagacagc aagtcattcc
     1021 ctgcatacat cccactccca cccgtgtgga agaccgaata tccggcaaaa acaacccttc
     1081 ctctcccgtc agcataaaac tccatagcga aatcttccac cttattatat ataggttcgc
     1141 ctaccacccc accctgagaa gcagcgacac gggcacacca accggaaata aaagtagtaa
     1201 atatgccttt acaccaattc aatcctttcc cgcttccgga aagcggagct tttaacaagc
     1261 acgcttcccg cccttcgacg aacgcactgc actccgccaa agtactcaaa taaaaagatt
     1321 ctccacagaa gtattcattc aaccgcaacc caggcaacaa ctttaccgcc tgcagacgat
     1381 gcgaatgctc tctcagaata ttcatataat ccgcagaagg cagctccgtc tgacctgccc
     1441 ccaatgtcat caaacgcttc cgcaaagcag ggtcccaacc ccacggagag aacttccagt
     1501 ctttaccgtc agccacttcc ggttccgtca acaaggccac atccatgccc aaaagttcac
     1561 tctttgtttt caggaagtcc gcattataag cagacggtgc aagcaccgca cttcccgctt
     1621 cggcatacca cataggaagc aacgccaggt cactcgccat ctgtcgggcg gaagccggcg
     1681 ccatatagtt cgtctcaccg cttgccaacg ccatatcatg ctccggattg aatatataaa
     1741 caggtctttt cgtcatgtca aagatggatt caacacatta ttctgcaaat atatacagga
     1801 aataatcagg aacttacaca ataaagagaa acttataaat taaagcacat ttttgctatc
     1861 tctactttgc aaatcctaaa aaaagcacta tatttgccag ccgaaaaaca aagaaacgaa
     1921 atggaatcat tctatcgcac acacgcctac ctcgttgagc acaccaatgc ccccgttcgc
     1981 cgcgatctta tggacgagat cgactggagt gaccgtctga ttggtatcaa agggacacgt
     2041 ggcgtaggaa aaaccacttt cctcctgcag tacgccaaag agaaattcgg caccgaccgt
     2101 tcctgtctgt tcatcaatat gaacaacttt tatttctccg gtcacagcct tgttgacttc
     2161 gccaacgagt ttcagaaacg tggcggaaaa gtactgctga tcgaccaggt gttcaaacat
     2221 cccgaatgga gcaaagagct acgaatgtgc tatgaccgtt tccccagcct gaagattgtc
     2281 ttcaccggtt cttccgtcat gcgactcaaa gaggaaaacc tcgaattgcg tgacattgcg
     2341 aaaagttata acctgcgcgg attctctttc cgtgaatttc tgaacctgca gacaggaatg
     2401 aaattccggg catacagcct cgaagaaatc ctcagtacac atgaacagat agccaaagga
     2461 gtactttcca aagtacgacc gctggattat tttcaggatt acctgcatca tggtttctac
     2521 cctttcttcc ttgaaaaacg taatttctcg gagaatctgc tgaaaacaat gaacatgatg
     2581 gtagaagtgg atatcttgct gatcaaacaa attgagctga aatatctttc aaagataaaa
     2641 aaattactat atttgttggc tgtggacgga ccgaaagctc cgaacgtgag ccaactggca
     2701 agtgacgtac agacatcccg cgctacggta atgaactata tcaagtatct ggcagacgcg
     2761 cgtctgatta atctggttta cccgaaagga gaagaattcc caaagaaacc gtcaaagatt
     2821 atgatgcaca actctaacct gatgtactcc atttatccgg tgaaagtgga agaacaggat
     2881 gtactcgaca cgttcttcgt taacacttta tggaaagacc ataaggtaca taaaggagat
     2941 aaaaacgtct ctttcatggt agacgaagtg atgccgttca aaatttgtgc ggaaggtaca
     3001 aaaataaaga ataacccgga cgtgacgtat gcgttgcaaa aggccgagat aggccgcggc
     3061 aaccaaatac ctctttggat gttcggattc ttatactaaa aagatttatt tacttaaata
     3121 tttaatttag ttatgactaa acagaagaaa ttcatcacat gtgatggtaa ccaagctgca
     3181 gcacatatct cgtatatgtt ctctgaagta gcagctatct accccatcac tccttcttcg
     3241 actatggctg agtacgtaga cgaatgggct gccgcaggac gtaagaacat cttcggcgaa
     3301 acagtattgg tacaggaaat gcaatctgaa ggtggtgctg ccggtgcagt tcacggttct
     3361 cttcaggctg gtgcattgac tactacttac actgcttctc agggtcttct tttgatgatc
     3421 cctaacatgt acaagattgc cggtgaattc ttgccttgtg tattccacgt ttctgctcgt
     3481 acactggctt ctcacgcatt gtgtatcttc ggtgaccatc aggacgtaat gtcagctcgt
     3541 caaaccggct tcgctatgtt ggcagaaggt tctgtacagg aagttatgga tttggcaggt
     3601 gttgctcatc tggctactat caaatcacgc gttccgttca tgaacttctt cgatggtttc
     3661 cgtacttctc acgaaatcca gaagatcgaa atgttggaaa acgacgacct cgctccgctg
     3721 atcgaccagg aagctttggc tgaattccgt gcccgtgcac tgaatccgat gaagccggtt
     3781 gcccgtggta tggctgaaaa ccccgaccac ttcttccaac atcgtgaatc atgcaataac
     3841 tactatgaag cagttcctgc tatcgtagaa gaatacatga acgaaatttc caagatcaca
     3901 ggccgcaaat acggtttgtt cgattactac ggtgcagaag atgcagaacg cgtaattatc
     3961 gcaatgggtt ctgtaactga agctgcccgc gaagctatcg accacttggt agcaaacggc
     4021 gaaaaagtag gtatggttgc cgtacacttg tatcgtccgt tctctgctaa acacttcctg
     4081 gctgctgtac ccaagactgc aaagagcatc gcagtgcttg accgtacaaa agaaccgggt
     4141 gctaacggcg aacctcttta ccttgacgtt aaagactgct tctatggcgc agaaaatgct
     4201 cctgttatcg ttggcggtcg ctacggtctg ggttcaaaag ataccactcc ggcacagatc
     4261 atctctgtat tcgaaaactt ggctatgcca atgccgaaga accacttcac tatcggtatc
     4321 gtagacgacg ttacgttcac ttctcttcct cagaaagaag aaatcgctct gggcggtgaa
     4381 ggtatgttcg aagctaaatt ctacggtctg ggtgctgacg gcacagtagg tgccaacaag
     4441 aactctgtta agattatcgg tgacaacacc gacaaacact gtcaggctta cttctcttac
     4501 gactccaaga agtcgggtgg tttcacttgt tctcacttgc gtttcggtga tactccgatc
     4561 cgttctactt acttggtaaa tactccgaac ttcgttgctt gtcacgttca ggcttacctg
     4621 cacatgtacg acgtaacacg tggtttgcgt aagaacggtt ctttcttgct gaataccatc
     4681 tgggaaggcg aagaactggc taagaacctg cctaacaagg tgaagaaata ctttgcacag
     4741 aacaacatct ctgtatacta tatcaacgca actcagattg caatggaaat tggtttgggc
     4801 aaccgtacca atacaatcct tcagtctgca ttcttccgta tcacaggcgt aatccctgta
     4861 gatcaagctg ttgaacagat gaagaaattc atcgttaagt cttacggcaa gaagggtgaa
     4921 gacgttgtta acaagaacta cgctgctgta gaccgcggtg gtgaatacaa gactctgact
     4981 gtcgatcctg cttgggctaa cctgccggat gatgcaaaag cagaaaacaa tgatcctgct
     5041 ttcatcaacg aagtagttcg tccgatcaat gcacaggacg gtgacttgct gccggtatct
     5101 gcattcaagg gtatcgaaga cggtacttgg tatcaaggta cttccaaata cgaaaaacgt
     5161 ggtgtagctg cattcgttcc cgaatggaat gctgaaaact gtattcagtg taacaagtgt
     5221 gcttacgttt gtcctcacgc ttctatccgt ccgttcgtac tcgatgctga agagcagaag
     5281 ggtgctaagt tcgagcaact gaaagctgta ggtaaagcat tcgatggtat gacattccgt
     5341 attcaggtag acgttctcga ctgtctgggt tgcggtaact gtgccgacat ctgtccgggt
     5401 aatccgaaga agggtggcaa ggcattgacc atgaaacacc ttgaaagcca gttggccgaa
     5461 gctgataact ggacttactg cgctgaaaac gtgaagagca aacaacacct ggtagacatc
     5521 aaggctaacg tgaagaactc tcagttcgca actccgttgt ttgagttctc aggcgcttgc
     5581 tccggttgtg gtgaaactcc gtacgtgaaa ctgatttctc agttgttcgg tgaccgtgaa
     5641 atggttgcta acgctacagg atgttcttct atctactccg gttcagttcc ttctactccg
     5701 tacactatga acgaaaaggg tcacggtcct gcatgggcta actccttgtt cgaagacttc
     5761 tgtgaatttg gtctgggtat ggaactggct aacgaaaaga tgcgtgcccg tctggtgaaa
     5821 gtaatgaacg aagctatcgc ttctgattgc tgcccggctg aatacaaaga agtatttgct
     5881 gaatggatca acaatatgct ggatgcagaa aagactaagg aactggccga aaagatcatt
     5941 ccgatggtag aagctgctaa agataaatgc aaccactgca agcaaatcgc tgatctgcaa
     6001 caatatcttg ttaaacgcag ccaatggatc atcggtggtg acggtgcttc ttatgatatc
     6061 ggttacggtg gtcttgacca tgtaatcgct tccggtaagg acgttaacat ccttgtattg
     6121 gatactgagg tttactctaa cacaggtggt cagtcttcta aagctactcc ggtaggcgct
     6181 atcgctaagt ttgctgctgc aggtaagcgt gtacgtaaga aagacctcgg tctgatggct
     6241 actacttacg gttatgtata tgttgctcag attgctatgg gtgctgacca ggctcagact
     6301 ctgaaagcta tccgtgaagc tgaagcatat ccgggaccat cactgatcat cgcttacgct
     6361 ccatgtatca accacggtct gaaagccggt atgggtaaga gccaggaaga agaagaaaag
     6421 gctgttaagt gcggttactg gcacttgtgg cgttacaacc ctgctttgga agaagaaggc
     6481 aagaatccgt tccaactgga tagcaaagaa cctaactggg aagacttcca aggtttcttg
     6541 aagggtgaag ttcgttacgc ttctgtaatg aaacaatatc ctgctgaagc tgaagaactg
     6601 tttaaagctg ctgaagaaaa cgctaaatgg cgttacaaca gctacaaacg tcttgccaga
     6661 gaaaactggg gagctgatac agctgaataa taagtagaaa tactttatac ataataaaag
     6721 gcaggaatcc tggaaacaga ttcctgcctt ttttgtttat atcttagaag taacgattac
     6781 ttctcacgaa gatattcatt aaaactctaa agatatgatc ggatttgtta tttggattat
     6841 cggtttgata ctgactttca gagctgccat agagatttgg aatataaatg cggctgtaga
     6901 gaaaagactt atagcgattg tattaatcgt tcttaccagc tggctgggac tacttttcta
     6961 ctacttctat ggtaaagaaa gaatggcagg atggttgaag tagtgtttgc atatcaatct
     7021 ttctcaggaa tccaactgtt taccagttcc tgatgttctt ccatccattg acgggcagcc
     7081 tgtctttccg ttgtctgcgc ctcttccaga gcagtcatta aagagctgat ttccgcatct
     7141 gtcagacgaa tgttgcccaa aagttcggca gcaaaagggt ctttctcgct aaaacctttc
     7201 catgctatgg tatgaatgga ttccgtattt ccatatatca gcttcgggtc ctgaagaact
     7261 ttcagcttga aacggtcgaa catccagtga ggcgtccatc ccgtcacgac aatccagtct
     7321 ttcttatcaa tcgctttctt tagggaagca gtcatggcag gtccgctcga agtcatcagt
     7381 ttataatcca atccatagtc tttgatggcc tgatcggtag ctttcataat accggctccg
     7441 gcatcaatac cgacaatctg accggagaaa cgttcctttt ccgcgttcag ttcttcgatt
     7501 gagttgatcg taacgtaatc cggaatcacc agcccgatac gggcaccatc ataaatatcc
     7561 ccgataactt cgagtttatc cccgtattgt ttcatataat cttccatagt gacaggcatc
     7621 cagacatcca taaatacgtc tgctttctta cgggagatag aggtaaatat aggtgcaagg
     7681 tcggcattca gcaactttac atcgtacccc tgatcttcaa aaatcgcttt ggcaaggttt
     7741 gtcattgcaa taccttccga ccagttggca taagcgatac ttatcttctt actctttccg
     7801 ttgtctccgc aggaaacgaa ggttaagagt atgccggcaa taaacattgc cgcaatcatt
     7861 tttatcttat tcattgatta ttcctttctt tggtgtgatt cttatttctt tttacttttt
     7921 ctgttatctg ccataccctg agtgatgcgg tccagcacga tcgccaatat cacgactgcg
     7981 ataccgcctt caaatccgag tccgattttc atttgggtga tacctttcag cacgatttct
     8041 cccaaccctc ccgcagaaat catggcggca atcactacca tcgaaagtga catcatgatc
     8101 gtctgattga ttcccgtcag aatagtaggc aatgccaaag gcaattgcac cttataaaga
     8161 agctgccagg gagtagctcc aaaagaacgg gaggcttcta ctacattttt aggaacctga
     8221 cgaatgccca gaccagtcag acgaaccaca ggaggcattg caaagatgat ggtggcaaaa
     8281 gctcccggca cagttcccaa tccgaagaat agaacggcag gaatcagata gacaaaggca
     8341 ggcattgtct gcataaagtc gaggacaggg cgcattatct tgttacaacg atcactgttg
     8401 gcagtccaga ttcccaacgg aacgcctaaa agcaatgcca gacaagtgga agaaagtacc
     8461 aatgccaatg tctgcatcgt ttcttcccaa aagcccatgc cgtaaataag caataaaccc
     8521 aagagggtaa atacggctgt ccccttaccc gacttaaacc aggcgagcgc agccagcact
     8581 gcaattgtga tataaaaagg tattccaaac agtacgtgct gaaaaccgtc tatgaatcct
     8641 ccgatcccca tgctgagagc atcaaaaaag gaagcaaaat gttctgtgag ccaattaatg
     8701 gcagtctcta tatattgtcc gatatttatc ataattctat tgcgttttga atgatttcat
     8761 taatttcttc tttatctttt cccgttactt cgatgatcaa tgaggaaagt ggcactacgc
     8821 cttcaaactc ccgattctca tttacgaccc agattggcga gttcgttttt gtcatcaacg
     8881 gaagaatatc ttccagcacc gtatcaccca gcactgaatg aacttcatgc cttactacgg
     8941 actcgatgga gcggatttgc tcttttcgta gtttcagcaa gtcattcaac cgcacctctc
     9001 ctactaacag attattggaa tcgactaccg gaagaacggt cagattccgt tcgcgcatct
     9061 tacggatcag cacctccggg ccttctttct tcaaacgtgc cactatgggt ttatctacca
     9121 taacagagga agctgttata atcttgcttc gatctacatt ctccacaaat cgttctacat
     9181 aagcgttggc aggttcggtc aggatttctt ccgatgtacc gatttgtaca atttctccat
     9241 ccttcatgat agcaatccgg tcacccaatt taatcgcttc actcaggtcg tgagtaataa
     9301 agacaatcgt ttttttcatc ttcgactgca aagtcagcag ttcatcctgc atctgcacac
     9361 ggatcaaagg atcgagtgcc gagaaggcct catccatcaa caggacttcg ggattattgg
     9421 ccaaagcccg cgccagcccg acacgctgct gcatcccacc cgacagttca cttaccatct
     9481 gattctcgta gcctttcagc cccaccagtt gcatactttc catcgctttc tgctcccgtt
     9541 ctcccttttt tactccctgt agttcgagcc cgaaagctat attatgcaag acagaacggt
     9601 gaggaagcag accgaagttc tgaaagacca tagccagttc tttccggcga atctgcaaca
     9661 gttccttatc cgacactttg gctatgtctg ttccattgat aatcacttct ccggaagtag
     9721 ggcgtatcaa acggttgatg cagcggagta aagtggactt tccactaccg gacagcccca
     9781 taatgacgaa tatttcgcct tcattaatgg aaagattcgc atctttcacc gcaactgtac
     9841 atccggtcgc tttcaatatt tcactttttg ttttaccttc tttcaacatc ttcaaagcct
     9901 tctgcttctc attgccaaaa accagataga gatctttaat ttctatttta ctcatacaat
     9961 aaaatggttt aggttattaa aataatatac acagcaagac aagaacaaac gataacagga
    10021 atctttcttt atatcgtata aagttctgat ttaaataagg gacaaataac aatgaatccc
    10081 gaaataatta ataaaatgat tattgacaga ctgagtaatt aaaaaaggaa tagaatttga
    10141 taagataatc ctttcaacga atagcaaaaa atagcatttt tatgtataaa aacagcctgt
    10201 tccagtatct tgctggcaca aagatacaaa aaacggatta aacatacaaa ttatattcaa
    10261 aatccggggc atacagaggg ctttatttgt aatgatatgg aaagtttccg ggtaatattc
    10321 ccctatcact cagcaaaata gaacaaaccg gcagataaat ataaaataag tttgaatatt
    10381 tcacttaaac accgtatatt tggcgtcaat aactaaacta gatttatatg ttcaacaggg
    10441 ctattacaat tttcctgggg aaggataatt gtcattacac aacaaaagaa aaacaaacag
    10501 gtactgccac actagacgac aaaagccaag tacagttcct tagtaaaaag aaccccaaaa
    10561 tgccgttttt ctatagccgg cggaatctct acatgatagg tttcctgctc gcttttatag
    10621 tgactctgct cgaatttata cgaggacggc atcaaaactt tatggtcttc tcggacgcta
    10681 ctcaattctt ctggcaaggc atcagcccat acacaactga atttgtagaa gctcacggac
    10741 gcaacttcct ttattctcca gttttcacgg tattgttcgc tccgtttgcg tatctgcctg
    10801 catggctggg acctttcgcg tggaatctat tcaattattc gctgttcttt atggcgatct
    10861 tcacgctgcc ccaacaattc acccagcagc agaaatgccg tatgttcctt tttctgttac
    10921 tgattttagg acaaagttta ctttcatttc agtataacat aacggtagcc tatttattct
    10981 tattcgccta tacgttattg gaaaaagacc gtggatttct ggctgttctg ttaatcatga
    11041 tttcgggatg taccaaagta tatggaattt tcgaactggc attgttgctg tgctatcctc
    11101 acgtatggcg taactttggc tatgccgtta caatgggcat tgtattgctt gcattaccgt
    11161 taatcaaaat agctcctgca gatttgctcc cctattatga agaatggtgc catagtcttg
    11221 ctgttcatca gtccgccgga gcttatgatt catttttcta tgcccgcccc attgcagcat
    11281 ggacattgcc acacctccgt gcacttcaga taggaatgct cggcttgctg actctgctct
    11341 ttttggggaa tttccgcaaa tggtcgtctt ttgccttccg tgcccaggct ttgggcattc
    11401 tcatgggctg ggtagtatta ctgagtgact ccgccgagaa gcatacctat attatcgcat
    11461 tggcaggttt catgctctgg tattggagca gaccaacacg taccgcaaca gacaagattc
    11521 tattttggtg ctgttttgtg ctgttatgta tcgttcctat cgacatattc gtccctatac
    11581 ccatcagaga tttcattacc aggaccttat ggcttcatgt atgggttttc tttattgtat
    11641 ggatacggat gatatggctt accttccttg catccttcat tcatccacgt gccacaaatg
    11701 ttctttcaga ttaacgcatc cgttagcttt gaaagaaact tcttctgcca gcaagagttg
    11761 tttttgttcc acccaaccgg gcaccagcct tccggtggaa tttacaactc tatggcaggg
    11821 aatggataat tcatccggca cttctttcaa tgcacgtccc accatccgcg agcattgggg
    11881 tgcccccaac agcaaagcaa tacctccata agtagatact tttcccacag gtatctggga
    11941 tacgacttcg tacacttcct tccgaaagga ttcggaaaag ctctctttat ctactttata
    12001 atctttcata tatccctctt tacgatatca atgaaatcat cctttccttt tcaggaaatc
    12061 tgtcgggctc tctccaaact gctctttata gcacttggcg aaataagaag gtgaactgaa
    12121 accgacttca taaccaatct ccgctacggt catgtccgaa gaagcaagca aagaagctgc
    12181 cttcttcaaa cgggcgatac ggagcaattc attcggagag tagttagtca atgatttaat
    12241 cttgcgataa agctgcacac ggcttagtcc catgtctttg cccaagtcct ccacattcaa
    12301 accggagtct cccattttct cttcaatcaa tgacttgaat ctttctacaa aatccttgtc
    12361 catatcgcag acatcttctt ttgccaatgt ctgcccgtca ccaaagaact gtttcagacg
    12421 acggtgagaa tcgatcagat tgcggacacg tgccagcaac agctgtgaac tgaacggctt
    12481 tgaaatataa gaatccgcac caccgtcata tccctgaata cgctgttcgt ccagtgaaca
    12541 cgctgtcagc agaataaccg gaatatgaca ggtctgtaac tcacttttca gccggcggca
    12601 acattcaatg ccatcaatgc ccggcatcat cacatcagaa atgatcaggt ccggaacata
    12661 cttcatagcc ttacggattc cttcggagcc gtctgccgct tcaatcaccg tatagtctgt
    12721 atgcaacaac gtatggacat acgaacggat atcctcatta tcatcaataa tcagtacgga
    12781 cggtttggaa gagtcatatc ctttttccag ttcttcctct tccgccaata gaacatctgt
    12841 tgtacgggaa tccgcagaaa caagggtggt atccggttcg gcagcaacag cctcacaaga
    12901 ctgtacaggc agttcaacgg taaagaccgt gccctgtttc tcatcgctct ctacggagat
    12961 cataccaccg tgcatttcta cgaaggcttt taccaatgcc agtccgattc ccgaaccggt
    13021 atggtgcata tcgatcttat agaaacggtc gaatacattg cgaatatgtt cggcagaaat
    13081 catagaaccg gtatttgcca ccgtgaaacg tatccatcgc ttgtcctctt tactaaggga
    13141 agacagacgg acggctattt tcccgttttc cggtgtaaac ttaaaggcat tggacagaag
    13201 attgaaataa atacgttcca gcttctccat gtctgccagt gtatgataat ccgtatccgg
    13261 catactatca aaagaaaaat ggatatgctt cttacgggct gccgcctgaa aagactcatt
    13321 ccatccttcg aaagaagaaa ggacatccac cgtaaccgga gtatattcca tcttgccgtt
    13381 ttcatattta cggaaatcca gaatctgatt gaccagacgc agaagaatgt tcacattccg
    13441 ctgaatcagc atgagcatcc ggtgctgatc tccgctcagt gtcttgtccg ccaacaaatg
    13501 ttctaccggg tcggcaacca atgtcaacgg agtacggaag tcgtgagaaa tattggtgaa
    13561 aaagaccagc ttggcatggg tagcttcttc cagttgatga gagagctgta tcaattggtc
    13621 acgctgttct tccagtttgt cacgctgctc ttccaattgc tgcttctgct taaaaagctc
    13681 tttattcaag cgattcttag agcggagtga tttataaacg accaataata agccggctac
    13741 caataaaagg ataatcagac tgccgtataa aacgacctgt tgtgtagcta cctgagagag
    13801 atagccaccg atacgtccgt tgagcgtttc aatctttttg tcgagttcgg aaatgtgtgt
    13861 ggtctgcaac tgcatgacgt gtgcgttggt acggtccaca acagcggtat tcatcaccgt
    13921 ttctttggga tagggtttct tctccagaat gtccatagcc agttgcagta ccttatcgcc
    13981 attggtcgga tagataaagg tggcatccag cacactgtcc agtaccagtt ccagtccgtt
    14041 tcccttaccc ggcaaggcat ctatgccgac aaaaatcatt tccttctccc gccctgccat
    14101 ctttgctgcc tgataggcac ccggagcgat acggtcatta tgggcataca cagcatcaat
    14161 cttaggatgc ctccgaagca tactatccat ttctatctct gccggaccac gttcccacgc
    14221 agcatccgct ttatcaatca gctttatatc cgggaattta ctgatggcag ccataaatcc
    14281 ctgatgccgt tccattgcag gagtcgaacc gctcaatcct gtcagttcta ctatatttcc
    14341 cttccctttc agactggagg caatatagtt tcctaccgaa cgaccgattt cataattatc
    14401 ggctccgata taggcagtat atttatccga aagaatcttc cggtctacaa gaataacggg
    14461 gatgcctttc tgataagctt cttctacaat cggagtcata ggagcagctt cgttagcgga
    14521 aataatcagc agatcgactc cttcgtccat aaaataatgg acatcttccg cctgcttact
    14581 gttatcatcc cctgccgaac ggatttccac cgaaacacca ttataaaaca tcgcttcccg
    14641 aagaatctca tcattcatct tatgtcgcca tgaatcatcg ctgcattgag ccaccccaat
    14701 acgaaaacgg ggtgtatcct gccggcaagc cgtcatcccg attaaaccaa acagcaccag
    14761 catccacttc agatatctca tcgtcttcat ccatctcatc atttcatagt tctttctgta
    14821 atccaattaa gaacaaaaat aagaaataat actgtaaagt tctctaactt cagctattta
    14881 ttattctaaa aagaaggaaa gcagtcctct ttcagaccat cggaaagtat taacaaaagt
    14941 ataaagcgta aaacaaacac ttaatcaatg ttataaaaca tagcgtttta cttggataat
    15001 ttgcagattt cacagaagtc cgtatctttg cactgtgttt ttcatagtat tagatttaag
    15061 gttaacaaag gttggagcaa ggcgttgctc ctttttttat gctctgacct ttcatctacc
    15121 ggttagtttt catcccattc cttttccagt ttaccatcaa tagtgtagcg tttccatcgt
    15181 cctacacggt gaccattctt atattcccca cattcacgaa gctggtcatt ctttacataa
    15241 cgagcttcga acggtccgtt ctgccttccg ttcacatagg tagaagtttc ccaataatca
    15301 aagcggttgc tcactatcag ccgtcgttcc ttgccatgca atctgccggc ctgataggta
    15361 gcttcatatc tcaattcacc attttccaaa ttatattcac ggtataaacc gtctttacga
    15421 tcgttcttca tataatattc tttctgcctt accccacttc cgttggcaaa tgagacatgg
    15481 agtccatctt cttttccatc cagataggtt tcaatcatca gcgtatctcc gctttcagca
    15541 aaagtagtcc aacgaccatt cttctttcca ttcttataac tacccagtat acgtggcgag
    15601 ccaaacgtaa acacggacga atattcaccg tcctgaaaac cttcttcatt gaaataaacg
    15661 gtctcataca aatcatatgt acctttcaga aaagtatact gtttgcctac ctgcttcccg
    15721 tccttgtaat tatgctcttt ccgcaaagta ccgtcagatt cgtacgacag ttgcttcccg
    15781 tgctctttcc ccatccggaa gtttctttca ctttccactt ttccggtagt aaagtaactt
    15841 ttgctcgtac cgtccagctt accttcctta taggactttt cttctttcag cttaccgtca
    15901 aacttggagt taatcttgaa gaggccatcc ttccgccctt ctttataact tccttccgtt
    15961 attaatatat tgtccacata ttctttgtat ccgccatcat aaaaaccatc tttaaaagat
    16021 gccagcacat aggcggaatg ataaccatct atgatgcgat gttcgccatt caatgctttt
    16081 tccgttttca gttcctgaaa caacagtctg ccatcgccta cattaacaac agatacctga
    16141 tcgatcttat attccttttg cgcaaacaaa ggaagagcaa gatataaaaa caaaaatacg
    16201 ttccagcttt ttgatctgag gaagttcgaa atgtgtttca taaagtagtt ttctcttttt
    16261 gatttattat ttaaaaacct gccgcaaaga taggcaatcg gcttataaaa caaggcaaga
    16321 aagaggggga caattagaaa aaagaacatc tgttattatc attctaataa ttaacagatt
    16381 aagtagtaaa tcaaaacaca gggaaggggg acatttactg aaataagaaa cagaaaagaa
    16441 gatgtgtcaa aagcaactaa attcccctcc ttcaggaagg aggagagttt agttgctttt
    16501 gacacattta catttgcagt attaaatatc acaacaaaat ataagtgtat atttgaaaag
    16561 tagagttgca gt
//
