LOCUS       c00018_gnlPro..        14300 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDLGEMBP_36.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:04:30
            Original ID  :: gnl|Prokka|IDLGEMBP_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14300
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14300
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[810:4300]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      811..4300
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14300
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14300
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2..256)
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MNPPHRSSSVHRSAVPGYRKWYFGAGGSPGRRGMEAAPEPDPLPF
                     EAIRIHEERTVGPPSTPADGYSAQGTFTIPEGADGKKLYG"
     CDS             complement(811..1578)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="Fer2_3 (E-value: 9.3e-24, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.1e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.8e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIASGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1619..3577)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.7e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.9e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3599..4300)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.1e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4501..4773
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAATRAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4776..5591
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5625..5903)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="VGKWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRN
                     ICLLAAAGAYILTPDEFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(6290..7024)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="LHHFIKILTMNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFA
                     SQTADFGTLKDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTA
                     LFNAKNSSVSWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIY
                     FGDSTTCYSNSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIP
                     EPATASLGLLGLAALMMRRRRA"
     CDS             complement(7501..7734)
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MECSFSLGRSTCATGFSVHHPRFTAVPKIPLSTNRALCLCLRVSN
                     DFSRQARHSRGVIKRTGLRAISGQNLNKRRLI"
     CDS             7739..8299
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="VLSLEEMRRLLAAAEEYDGGACLAAVGLMLYAGIRPEEVRRLDWA
                     QINLREGMVSLRARHSKTGGARIVTIQPVLGNLLERAVAMGSVSGSVCPRNWPAKWREL
                     RRLAGWDGKEKKWPADMLRHTFASYFARHFKNLHVLQMEMGHASSDLLRTRYLNMEGIT
                     EMTAAVFWGNCHAGRHAIKNGRP"
     CDS             complement(8342..9673)
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MKTYTLPVIGLMTLGASAFAAAAPSTGNSLPARDNFSACKWLGDR
                     FKWFNSERDHKNPYIQEFNVSLRMQYGLDWIDPNGEGRVMGEKEGNGHRFNDEWRRFRA
                     GFNMKFLNNFKLNNVWNIGGMDGLESYNAKTNTWDTSDLTYSLYELNLEYKGGPVTYAI
                     GKIKPRITGEYRTSSSAILTIERSMLVNQLRSETNYGFQVNNSDKKDKLGWAAGVWLNG
                     NGGTGTGTFNNRIEPAFNSRDNCFITGTLSYDTSNDVFLKKSRLWLDYAHNFTKWGDDA
                     QNKAYEKLTGYGFKSKYQGTGARDVVALTWEGSEGDFSLMTEVMAGFNVIGMKAGAENV
                     FGVTVMPSYKFTPHWEGVVRYQMAAGSNAVKWEKRYTQNSTYSGTSDCMQALYLGVNYY
                     IFECSPNMAKIMAGIEYAHSNGTDASRQKGFTGWSYNIAFRTNF"
     CDS             complement(9817..10626)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MSKLWSGRDDAGKQIPSPPGSSLRLELHFRNGGPSISGMNHTALE
                     DKLGYRFNNPDLLVQALTHPSTDSKPETRRAYERLEFLGDAILQLAVTQYLYHHMPQSP
                     EGELTQLRARTVSRANLGKYGFILGLDKHIALGKGEERAGGRSKNSIIANTFESVFGAM
                     SLDSNYETAKAVALRVLHEALDSAASHPKEINPKGELQAILQDILPETPSYETEEKGPR
                     DAENRFESRVFWHGHAIGAGSGASKRKAEVAAAADALDARAWLRMTL"
     CDS             complement(10702..11256)
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MEPLPPSEKARTETTNRRPPAAFPGRYSFTHTFRISTIYILWKSP
                     AAYHSGTIDLSRKASGLRGSAYSLRHSNTRRASVKLTLPFSVTYGVRPEAATLSVSRPL
                     VVPHTVRALWYSWLKKESVSSSPASIKRKVWRWGRITTNATGFFHMNPKPPQLAVIMLK
                     CSGEPAVTSIQSPPINCTALS"
     CDS             complement(11234..12289)
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="MISRLKLMDFRCYGSFSWQIPQQGAIILGNNARGKTSLLEAVCFL
                     LRLQSPRTARTGPLVSHGKQSFGIRGELPGQIRRILWAPDAPDLRVNGEPRKDQRSYLA
                     DSYPVVWMGNDDLSLVQAGADARRKYMDFLGSQWHPGYRLALFSYRRALKTRNYLLKHR
                     HRDKLQLDAYTRQLALHGTELRNLRAHLLALLAPHIALAYRNIGGRQEQVSIAYRASEE
                     GDLYERLCASMDRDIRYGQTQNGPHRDDLDITLNGRNAAQFASEGQQRTTAISMKLAQS
                     SLLTEETGHTPIHLIDDVFGELDPTRRIAFLQSLPADAQSLITTTHLDWLHDAPCPLPA
                     FRLEDGTLAPL"
     CDS             complement(12308..12919)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_15"
                     /sec_met_domain="Acyltransferase (E-value: 1.2e-24,
                     bitscore: 77.3, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSFYWVFYTLFKSISKAFFSWKVVNREKLIEDGPVLIVSNHQSF
                     LDPPMLGISYEDGIYFFARKTLFQGIFKWALPLCQAIPIDQENPDAASLKHVIRLLKSG
                     KRVLVFPEGSRTPDGKIHDGMGGIGLILSKTKVPVQPLRISGAYEAFPIGARFPRLRPV
                     TVTVGDPIPFTPAELNAKGKDAYQHLTDKIMDAIRSLPAE"
     CDS             complement(12916..13557)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_16"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.6e-69,
                     bitscore: 224.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPAIAIDGPAASGKSTVAKLIADRLGYTFINTGAMYRAVTWYML
                     EQGINPADTAAVLESLPAVPLSFGKDGSQSVVLCGQHVLGEELTSQQVNDHVSTIAAIP
                     EVRALLVERQREYNRREPVVMEGRDIGTVVFPDTPFKYFVTASEEVRAARRAAEGLTDS
                     IAERDRKDSSRATAPLAQAPDALLVDTSDMTIDQVVRFITDNIQQKLSSR"
ORIGIN
        1 tgccgtaaag ttttttgccg tccgctcctt ccgggatggt gaatgtgcct tgcgcgctgt
       61 agccgtccgc cggcgtgctc ggcggcccca cggttctttc ctcatggatc cggatcgctt
      121 caaacggtag cggatcgggc tccggagctg cctccatgcc ccgcctgccg gggctgccgc
      181 cggctccaaa gtaccatttc cggtagccgg gaacggcaga acgatggacg gaggaggaac
      241 gatgaggcgg attcatcagg tattcaagag tcgggggtaa tgaaggaagc gaggggggcc
      301 gccctttcct gatcgtttta tcaatagtat gatctgaagt cggtgtcgat agaattttat
      361 ttgtatgttt ttgatttttt ataaaagatg gtcattattt tacacgaaaa gataatatta
      421 taattcttac gttcagtgca ttcccttaat agacatcaat gttgtctgtt tgttagaaaa
      481 tgttttcctc tcatgctgag cccttgacag gaggccatcc cttccgggca tcagtccaat
      541 tcctgtaatc aatgtttttc tttctcgaag aaagatgggg ccgtcgctgt cggacggggc
      601 ctgcttaggt ttcgtccggc atttccaagt acggtctcct ggattactgg gaaccttccg
      661 gtgtaacatt tattttttac gctgcgcgac gatgaggaag caactgtctg atattttatt
      721 cctggttcaa ggaaacctga taatgaaaaa aactcccgac agccgatgcc gccgggagtt
      781 tttacagagc gtcttaagaa ggaatcttct ttagaaacag agaccttcct tggcgttggc
      841 tcgcatgaag tcgcggttga ggcgggcgat gttgtccacg ctgatgcctt tcgggcaggc
      901 agcttcacat tcatactggt tcgtgcagtt gccgaagcct tccgcttcca tttgcttcat
      961 catggccagg acgcgcttgg aacgttccgg ctggccctgc ggcagcagat tgagatgggc
     1021 gatcttggcg gaggtgaaca gcatggcgga ggcgttttta caggaggcca cgcaggcgcc
     1081 gcagccgatg caggcggccg cgtcaaaggc ggcgtccgcc ttcacttttt ccacggcgat
     1141 gttgttggcg ttcggcgcgg aaccggtacg cacgtcaata tagcctccgg aggcgatgat
     1201 gcggtccagg gcggagcggt ccaccatcag gtcccgcagg attgggaaag ccttcgcgcg
     1261 gaagggttca atccagacgg tatcgccgtc cttgaacttg cgcatgtgaa gctggcaagt
     1321 ggtcacctgg cgttccggcc cgtggggaat gccgttgatg gtcagggagc acatgccgca
     1381 gatgccttcc cggcagtcgt ggtcaaaatg gatgggttcc ttgccttcct tgaccaggcc
     1441 ttcattgacg atgtccagca tttccaggaa ggaggcgtcc accggaatgt ccttggcggc
     1501 ataggtctca atgcggccct tagcttcccg gttttcctgg cgccagacct tgagagtgag
     1561 attgagtgtt ttagccatgt tataatcttt cttttgagtg ttaatgtatt ggctatcttt
     1621 acttgtagct gcggatggca aggtgcacgt tctcgaaggt cagcggttcc ttgtggagaa
     1681 caggcaggct gtccacgcca gtgtattccc aggcggctac ataggcgtat tcatcgtcgt
     1741 tgcgcttggc ttcgccgtcc ggcagctggt attccacgcg gaagtgggcg ccgcaggatt
     1801 cctggcggtt cagggcgtca tagcagagca gctgggcgaa ttccaggaag tcggccacgc
     1861 ggcaggcttt ttccagttcc gcgttgatgc cgtccgccgt gccggttacg cgcacgtttt
     1921 cccagaattc cttgcggagc tggggaatgc gttcaatggc gtgggtcagg ctttcttccg
     1981 tgcgggccat gccgcagtct tcccacatga tgaggcccag ttcccggtgg aaggagtcca
     2041 ccgtcttggt gcccttcaca ttcaggagct tgttgatgcg ttccttcact tcgtcttccg
     2101 cagccttgaa ttccggggcg gcggtggtga cggcaccggg cttggtggtc gtcaggtaag
     2161 cgggcagcgt ggcgggaatg acgaagtagc cgtcagacag gccctgcatc agggcggagg
     2221 ctcccaggcg gttggcgccg tgatcggaga agttggcttc accgaggacg tgcaacccct
     2281 tcacgttgga catgaggttg tagtccaccc acaggccgcc catggtgtag tgggaggcgg
     2341 ggtagatcat catgggcgtt tcatgggggt cgtcgtccgt gatttcttcg tacatgtcaa
     2401 acagattgcc gtattggccg tcaatccatt cgcggcccat gcgcttgatt tcatccgcaa
     2461 aatccaggaa gacgcccttg ccggtgacgg ccacgccgcg gccgtcgtcg caggcttcct
     2521 tggcggcgcg ggaggaaatg tcgcgcggag ccaggttgcc gaaggaggga tacttgcgtt
     2581 ccaggtagta gtcccgttct tcttcgggaa catcggaagg cttgatttcc ttcttacgga
     2641 ttttttctgc ggtttcacgg gacttgggca cccagatgcg gccgctgttg cggagggatt
     2701 ccgacatcag cgtcagtttg gactggtagt cgcctttgac cggaatgcag gtggggtgga
     2761 tttgcgtgaa gcaggggttg gcgaagaagg caccacgctt gtaggctttg taggcggcag
     2821 tgacgttgca acccatcgcg ttggtggaca ggaagaacac gttgccgtag ccgcccgtgc
     2881 agagcaggac ggtatcccct gcgtaggatt tgatttcgcc ggtaaccaga ttgcgggtga
     2941 cgatgccctt ggcttcgccg tccaccaaca ccaggtccat catttcatgg cgggagaaca
     3001 tttcaatgtg tcccttggcc acttcctttt ccagggcctg gtaggcaccc agcaggagct
     3061 gctggcccgt ctgtccgcgt gcgtagaagg ttcgcttgag ctgggcgccg ccgaaggagc
     3121 ggttgtccag caggccgccg tattcacggc cgaagggaac gccctgggcc acacactggt
     3181 caatgatgtt ggaggagact tccgccagac ggtagacatt ggcttcacgg gcgcggaagt
     3241 cgccgccttt aacggtgtcg taaaacaggc ggtaaacgga gtcgccgtcg ttctggtagt
     3301 tcttggccgc gttaatgccg ccctgggccg caatggagtg ggcgcggcgg gggctgtcct
     3361 ggtagcagaa gcatttgacg ttgtagccaa gttcggcaag cgtggcggca gcggaggcgc
     3421 cagccaggcc ggaacctacc acaagtaccg tgtacttgcg cttgttgttc ggattgatca
     3481 gtttggactc aagtttgtac ttggaccatt tgtcctgaat agggccggag ggaattttgg
     3541 catccggcat ccagtcgctt acgggaaaat taatcatgac tttgagagga gttgatggtt
     3601 atttgatgat acccagaaga accgagaccg gcacggagat gaagcccagg cagataatcg
     3661 cgccgtaggc gatggcgata aagttgtaga agggccggat tttgcgggaa tcgacgccca
     3721 cagtctggaa gatggactgt accccgtggc gcagatggct gaacagcatc agaacggcca
     3781 ggatgtagaa ggcggagcac catacgttgg agaatccggt cacgatcatc ttgtacacgt
     3841 caaaggtttc caccgtaccg tcggaaataa aggtggtgaa ctgggcgggg tcgtatccca
     3901 cgcgcagggt gtactggtac aggtggtaga tcaggaacac caggacggtc aaaccggtgt
     3961 aaatcatgta gcgggaggag agcgttgcct taatggtgtt cttgaacacg tagggttcgc
     4021 gggccgcatg gttttccagc ttcagctgga tggtcagcca gacgtggatg atgaagatca
     4081 ccgcaagccc cgcgcggatt ccccagaggg ctgcttccgg catggagtgc aggccgtggg
     4141 cgtaggtgtt gatccattca gggcctccga agatgagaag gttgcctgcc aggtgtcccg
     4201 caaggaacaa gaccaaacat aaccccgtca gagccacaat gattttgcgg ccgatggagg
     4261 atgtcacgaa tgtacatatg gtttttacta gtgcattcat aggcgctcta atgaaataaa
     4321 tgcgtcttca caggatgccc ggttcaagcc cggatggcaa gcctcttctt gaatttccgg
     4381 cgcttttcgg atttttgaaa aaccggggaa agaggttgct gtttatcagt ttggaatggt
     4441 tatcattttg ttgcctgttc cggcttgacg aggctttccg cacaggcgta tcgtctgtgc
     4501 atgaaaagaa gtaaaaagga ggtgctggac gcggatttcg cagcgacgcg cgccggcgtt
     4561 ctggatgtgg ccgcatttct ggaccgggtg gaccgcgggg aaggggaggc ggatttccgc
     4621 taccatgccc tgatggatgt tcttcccctc ttgtccgcat ccggccccgg acgcgtccgg
     4681 gccattctgg aagccctttc ctacagggat gacaccgtgc cggaaaccgc cgcagccaaa
     4741 gcggcctgcg gagccccgaa cctcagcaaa taagaatgat ggctttcata gaacctcata
     4801 tacatatggt gtgccgcacc acggacgaat accgggccat ggcgcaggcc ggctgcctgg
     4861 cggtagggga accggcgttc tgggccggtt acgaccgttc gtccgcggac ggtttccggg
     4921 attatttcgt acagcttacg gaatgcgaac ccgccagggc ggccaagttc ggcatggacc
     4981 attacacatg gctgtgcatc aatcccaagg aggcgcagga cgtggctttc gcgcgggatg
     5041 tgatgaaact gattccggag ttcattgacc ggcccaatgt cctcggcatc ggggaaatag
     5101 ggctgaaccg gaatacttcc catgaaatga ctatttttga agagcatctg gatctggcgg
     5161 tgcgcctcaa ccagcttgtg ctgattcaca ctccccatct ggaagacaag cttaagggga
     5221 ccgtaatgat tctttccgcc ctgaaaaacc gtccggatct ggacccttgc cgcgtgctgg
     5281 tggatcactg tgaggaacat accttcccgc tggtgaagga ggccggttac tgggccgggc
     5341 tgacccttta tcccaccagt aagctgaatc ccaagcgggc ggcggatatt ctggaattgt
     5401 acggaatgga ccgtgtctgg gccaattccg cggcggactg gggggattcc gatcccctgg
     5461 cgctgacggc cctggcctgc gagctacgca ggcgcggttt ttcccggcag gaaacggaac
     5521 gtcttctcct ggaaaatccg gagacattca tgggacagtc cccgaagttc cggaaagtgt
     5581 cgtcccgcta attccgcccg aggcgcggcg gagggtacgg ccctctagtc cccgtccggg
     5641 aaaaagacgg tgaggacggc gcccaggatg accgccgcgt catccagaag gcccagcctg
     5701 ccgattccgt caaacaggaa ttcgtcggga gtcaggatgt aggcgccggc ggcggccaga
     5761 aggcatatat tccgtttgtt gaaaaaacgc ggttctcctt ttctgctttt gaaataccgg
     5821 aacaggcgca gtagcagctg ctgtttttga aggttcatgg acgggaacgg gggataaagg
     5881 ttcaagctca gccattttcc cactcctttt ccctgtttcg gggaaggagt ctgttgccga
     5941 cggacggaaa ccgcagcgat ccggaccgtg cggggaaatg gattgctgaa aggatgggct
     6001 gttccggatg ctgagggaag ccgggctttg catgctccgg ttccggctgt cccggcatgg
     6061 gaaaaagggg cgtgtacgga agtggggcgg ggccggaagc tcttgaaatg accctcccgg
     6121 gggagcctga atgccatttc cccgtcaagt gctggccgtg agggtaccgc agcaaatgga
     6181 agcttcttcc cccctgtttt ttccggcaga tgtttgaacg gataaggaaa aggccggctc
     6241 acgattttgt gagccggcct ttgaatatag ggaggcggac ggtacaggct tatgccctgc
     6301 ggcggcgcat catcagcgcg gccagtccca gcaggcccag ggaagccgtg gcgggttccg
     6361 ggatgctggc gatttcactc atcagttgac caacttgttc ctgggaaagg agggagtcgt
     6421 gaatgtagag ctgttcgatg gattcagcca gtcctgcgtc catgagaatc tgatcaattt
     6481 gctggttgcc gaatttcagg ccgctgttgg aatagcacgt agtgctgtct ccaaaataga
     6541 tgcgggtgcc aagatctccg gtgactacgg aaatggtcag ggaaccttcc gtgcccagcg
     6601 gggtgtcaac gacaggcccg ctgtaggagg tgttgttcca taatccctgg agtttccggt
     6661 ccgtgttcag gcccacgccc cagcttacac tgctgttttt ggcgttaaac agagcggtat
     6721 aggcgtccgg agtgttgatt ttggacaggt caagaaccat cgtcacagac ataacgtcgc
     6781 ggttgttggc accgtatccg ttgaaggtta tcccggataa cgtcagattg ctgtcgtcag
     6841 acgtgatgga aacggaatct ttcagggtgc cgaaatccgc cgtttgggag gcaaagtccg
     6901 aatatcccac gatggagcta tccagcagag aggtagccgc ggtagcgctt aggctcatgc
     6961 cgaccgaaag aatcagggtg gataataatt tattcatggt cagtatctta ataaaatgat
     7021 gcaagattca atgtatgtac ttgtgcttga ataacgaatt tggaatccgt ataggaattc
     7081 ctgtgtcctc tttgtcatca aactgtctgg aagagaattg ctgatatgac ggtgcggtga
     7141 aacggcatga atgaagttgg cgaacctttt gattaataaa cgactatttt tacttgacta
     7201 cggattccaa aaccgttgca aaatatatga aatgagagag aaaatttcag caacggatca
     7261 tgcggcgctg gccattttaa aaaagacagg gctggatgtg gtggaagccg cccagctggc
     7321 gcatgaattg ctgcaggcca gcaaagggcg cggcagccga tggaagaggg caagggaatg
     7381 catccggctg ggagaggaag ccctggttgc cagaggaaaa acggtagtgt tcaggaaagc
     7441 cgtggatgag gctatggagg ctcggcaaga tcgcaggaaa agaactaggg atgattttcg
     7501 ttatatcagc cggcgtttgt tgaggttttg tccggaaata gcccgaaggc ccgtacgctt
     7561 tatcacgccc cgggaatgcc gcgcctgtct ggaaaaatca tttgataccc ttaggcagag
     7621 gcataaggcc cggttggtgc tcagcggtat tttcggaacg gccgtgaaac gcggatggtg
     7681 cacggaaaac cctgtggcgc atgtggacct gccgaggctg aaggagcatt ccattcccgt
     7741 gctgtccctg gaagaaatgc gccggttgct ggctgctgcg gaagagtatg acggaggggc
     7801 gtgcctggcc gcggttgggc tgatgctgta tgccggcatc cgcccggaag aagtgagaag
     7861 gctggattgg gcacagatta atttaaggga gggaatggtt tccctgaggg cgcgccacag
     7921 caagacggga ggagcccgca ttgtgacgat ccagccggtt ttgggaaatc tgctggaaag
     7981 agcggttgct atgggatctg tgtcgggaag cgtatgcccg cgcaactggc cggcgaagtg
     8041 gagggagctg agacggttgg ccgggtggga cgggaaggaa aagaagtggc ctgcggatat
     8101 gttaaggcat acgtttgcca gttattttgc caggcatttc aagaatttgc atgtattgca
     8161 gatggaaatg gggcatgctt cttccgattt gctaagaacc aggtatttga atatggaagg
     8221 cattacggaa atgacggctg ccgttttttg ggggaactgc catgcagggc gccacgccat
     8281 taaaaatggc cgcccctgaa cagaagcggc cagctgttga cgggatgata ccgtccggca
     8341 attagaagtt ggtgcggaaa gcgatattgt agctccatcc ggtaaagcct ttctgccggc
     8401 tggcgtccgt gccgttggaa tgggcgtatt cgatgcccgc catgatcttg gccatgtttg
     8461 ggctgcattc gaaaatgtag tagttgacgc ccaggtacag ggcctgcatg cagtcggaag
     8521 ttccggaata agtggagttc tgcgtatagc gcttttccca ttttacggcg ttgctgcccg
     8581 ccgccatctg gtagcggacc actccttccc agtggggggt gaacttgtag gacggcatga
     8641 cggtcacgcc gaagacgttt tcagcccccg ctttcatgcc gatgacgttg aagccggcca
     8701 tgacttcggt catcagggag aagtccccct cggaaccttc ccaggtcagg gctaccacgt
     8761 ccctggctcc ggtaccctgg tatttggatt taaagccgta accggtcagt ttttcatacg
     8821 ccttgttttg ggcgtcgtct ccccacttgg tgaaattgtg ggcgtaatcc agccacagac
     8881 ggcttttctt caggaaaacg tcgttagacg tgtcatagct cagcgtgccg gtgatgaagc
     8941 agttgtcccg ggaattgaaa gcgggttcaa tgcggttgtt gaacgtgccg gttccggtgc
     9001 ccccgttgcc gttcagccag acgcctgctg cccagccgag cttatccttt ttgtcggaat
     9061 tgttcacctg gaatccgtaa ttggtttccg agcggagctg gttgaccagc atggagcgtt
     9121 cgatagtcag aatggcggag gaggatgttc ggtattcccc ggtgatgcgc ggctttattt
     9181 tgccgatggc ataggtgacg gggcctccct tgtattccag attcagttcg taaagggagt
     9241 aggtcaggtc ggaggtgtcc catgtgttgg tttttgcatt gtagctttcc aggccgtcca
     9301 tgccgccgat gttccagacg ttgttgagct tgaagttgtt cagaaacttc atgttgaacc
     9361 cggcgcggaa gcggcgccat tcatcgttga agcggtggcc gttgccttcc ttttctccca
     9421 tgacgcggcc ttcgccgttc gggtcaatcc agtccagtcc gtactgcatg cggagggaaa
     9481 cgttgaattc ctggatgtag ggattcttgt ggtcccgttc cgagttgaac cacttgaaac
     9541 ggtcgccgag ccatttgcag gcggaaaagt tgtcacgggc cggcagggag tttccggtag
     9601 agggtgcggc agcggcaaag gcggaggctc cgagagtcat gaggccgatg acggggagag
     9661 tataggtctt catttgtttt ctatggttgg tttgtctgtg agaaggtctt ccggggaagg
     9721 ttcttcctcc cggagacggc ttctgtctat caaaccagcc acaggagtgt ccaaggctta
     9781 agggtgacaa aatagccacc cgtccccctt tggcggttac aaggtcatgc ggagccatgc
     9841 cctggcgtcc agggcgtctg cggcggcggc cacttccgcc tttctcttgc tggccccgga
     9901 accggctcca atggcgtgac catgccagaa aacgcgggat tcaaaacggt tttcggcgtc
     9961 tctcggccct ttttcttccg tttcatagga aggagtttcg ggcaggatgt cctgaaggat
    10021 agcctggagt tcccccttgg ggttgatttc cttgggatgg ctggccgcgg aatccagagc
    10081 ttcatggagg acgcgcaggg ccacagcctt ggccgtttca tagttggaat ccagagacat
    10141 ggctccgaag acggattcaa atgtgttggc gatgatggaa tttttgctcc gtccgccggc
    10201 ccgttcctcc ccctttccca gggcaatgtg tttatccagc cccaggataa agccgtattt
    10261 gcccagattg gcgcggctga cggttcgggc gcgcagctgg gtcagttccc cttccgggga
    10321 ttggggcatg tggtggtaaa ggtactgtgt gacggccagc tgaagaatgg cgtctcccag
    10381 gaattccagc cgttcatacg cccggcgcgt ttccggcttg ctgtccgtgc tggggtgggt
    10441 aagggcctga acgagcagat ccggattgtt gaaacggtaa cccagcttgt cttccagcgc
    10501 ggtgtgattc atcccggaaa tgctagggcc gccgttccgg aaatgcaact ccaaacggag
    10561 agagcttccc ggcggggacg gaatttgttt tcccgcgtca tcccggccgc tccacagctt
    10621 tgacatatgg gaggaggggt atagaatagt ttgcgaacga acgttggaga cgatgatgaa
    10681 gaagattgaa ccaaaagaga ttcaggataa tgccgtacaa ttgatcgggg gcgactggat
    10741 gctggtgacg gcgggttctc cggagcattt caacatgatg acggccagtt ggggcggttt
    10801 ggggttcatg tggaagaagc ccgtggcgtt tgtcgttatc cgcccccagc gccatacctt
    10861 ccgttttatt gaggccgggg acgagctgac gctttccttt ttcagccatg agtaccataa
    10921 ggctctgacc gtgtgcggaa caacgagcgg acgggatacg gacaaggtgg ccgcctccgg
    10981 cctgacgcca tacgtgacgg agaacggcaa tgtaagtttt acggaagcgc gcctggtgtt
    11041 ggagtgccgc aagctgtacg cggagcctct taacccggaa gcctttctgg ataaatctat
    11101 tgtgccggag tggtatgccg ccggggattt ccataaaatg tatattgtgg aaatcctgaa
    11161 cgtatgggtg aaggaatagc gtcccggaaa tgccgcaggc ggacgcctgt tcgttgtttc
    11221 tgtccgcgct ttttcagagg ggggcaaggg ttccatcctc cagccggaag gctggcaggg
    11281 ggcacggagc atcgtgcagc cagtccagat gggtggtggt gatgaggctc tgcgcgtccg
    11341 ctggaagcga ctgcagaaag gctatccggc gcgtgggatc cagctccccg aagacatcgt
    11401 caatcaggtg gatgggtgta tgtcccgttt cttccgtcag gagggaggac tgcgccagct
    11461 tcatggagat ggcggtggtg cgctgctgcc cttcggaagc gaattgagcg gcgtttctgc
    11521 cgttcagcgt gatgtccagg tcatcccggt gggggccgtt ctgggtttgt ccgtaccgga
    11581 tatcccggtc catggaggcg cacagccgtt catacaggtc tccttcctcc gaggcgcggt
    11641 aagcgatgga gacctgttcc tgccttccgc cgatattgcg gtaggccagg gcgatatggg
    11701 gcgccaggag cgccagcaga tgggcgcgca ggtttctcag ttccgtgccg tgcagggcca
    11761 gctggcgcgt gtaggcgtcc agctggagtt tgtcccggtg cctgtgcttg agcaggtaat
    11821 tgcgcgtttt cagcgcccgg cggtagctga acagggccag tctgtagcct ggatgccact
    11881 ggctgcccag aaagtccatg tatttccggc gggcgtccgc gccggcctgc accagggaaa
    11941 ggtcgtcatt ccccatccat accacgggat agctgtccgc caggtagctg cgctggtctt
    12001 tgcggggctc tccgttgacg cggaggtccg gagcgtccgg cgcccacagg atgcgccgga
    12061 tttgccccgg aagttctccg cggatgccga aggattgttt tccgtgggag accagaggtc
    12121 cggtccgggc tgtgcgcggg gattgcaggc gcagcaggaa gcaaacggcc tccagcaggc
    12181 tggtttttcc ccgggcgttg tttcccagga tgatggcccc ctgctgcgga atctgccagg
    12241 agaagcttcc gtagcaacgg aagtccatta atttcagcct ggagatcatg gggccgggaa
    12301 aggggggtta ttccgcaggg agggagcgga tggcgtccat gattttgtcc gtcaggtgct
    12361 ggtatgcatc ttttcctttg gcgttgagtt ccgccggcgt gaaggggatg gggtctccca
    12421 ccgtgaccgt gacggggcgg agcctgggaa accgggcgcc gatgggaaag gcttcatacg
    12481 caccgctgat gcgcaggggc tgcacgggaa ctttcgtttt gctcaggatg aggccgatcc
    12541 cgcccatgcc gtcatggatt ttaccatccg gcgtgcggga gccttccgga aacacgagta
    12601 cgcgcttgcc ggatttcagc aggcgtatca cgtgcttgag gctggcggca tccgggtttt
    12661 cctggtcaat ggggatagcc tggcagaggg gcagggccca tttgaaaatg ccctggaaca
    12721 gcgtcttgcg tgcgaaaaaa tagatgccgt cctcataaga aatgcccagc atgggcggat
    12781 ccagaaagct ctggtgattg ctgacgatga gcacggggcc gtcttcgatg agtttttccc
    12841 ggttgacgac tttccaggag aagaaggctt tggaaatgct tttgaagagc gtgtagaaaa
    12901 cccagtagaa agagttcatc tggaggagag tttttgttgg atgttgtcgg tgatgaaacg
    12961 gacgacctgg tcaatcgtca tgtctgacgt atccaccaga agagcgtcag gcgcctgcgc
    13021 cagcggggcg gtggcgcggg aggaatcctt gcggtcccgc tccgcgatgg agtccgtcag
    13081 tccctccgca gcgcggcgcg cggccctcac ttcctcggag gcggtgacga agtacttgaa
    13141 cggcgtatcc ggaaaaacca cggtgcctat gtcccttcct tccatcacga cgggttcccg
    13201 gcggttatat tcccgttgcc gttccaccag cagggcgcgt acttccggga tggccgcaat
    13261 ggtggaaaca tggtcgttga cctgctggct cgtgagttct tcgcccagca catgctgtcc
    13321 gcacagaact acggattggc tgccgtcctt gccgaaggag aggggcacgg ccggcaggga
    13381 ttccagcacg gccgccgtgt ccgcagggtt gatgccctgt tccagcatgt accaggtaac
    13441 ggcccggtac atggccccgg tgttgatgaa cgtatagccg aggcggtccg cgatgagctt
    13501 ggcgacggtg gattttccgg aggcggcggg gccgtcaatg gcgatggctg gatgcatgag
    13561 tgtcttctga gttggaaatg ggggctaaag ccgtttgaat tgtagctttg agccctgtgg
    13621 aaatcaagac tgcgttccga agggcgttgc aaaaagagtt tcactttttc ccgtaaatcc
    13681 gttatacagc ggggcatggc ccagctcaaa cacccgaaga tggtggacat cagagacatt
    13741 ttggacgaga atacgcgtct gcctgctctg gtggccgcgt ccgccgaaaa gctgctgggc
    13801 ctggaacgcc tgaacaaggc gtacgacaag atcgtgcgcg acaaagaatc cggttctcag
    13861 gaaaatttct ttcagcttgc ctccaggcat ttgaacctga agcttcagct gcgcccgggg
    13921 gacctggaaa atattcctaa gaaagggcct gtcgttgtcg ttgccaatca tccgcacggc
    13981 ttgtcggacg gcatcatgtt cggggagctg cttacccgcg taagagagga tgtccgcatc
    14041 ctggtcaacg agcagctttc cctgtgcggg gagctggatc cctggctcat caaggtggac
    14101 gtgtatgagg atgagaacgc ccggcgcaaa aacctttccg gtatgcgcaa gatgatttcc
    14161 tggctgcggc agggcggggt tctgggcatt ttccccgccg gcacggtctc cagtttttcc
    14221 ctggcccaca aaagggtgac ggacgaccct tggaacgcga atatcgccgc cattatccgc
    14281 atgacgaaag cgacggtggt
//
