LOCUS       c00022_gnlPro..        14742 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDLGEMBP_40.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:04:30
            Original ID  :: gnl|Prokka|IDLGEMBP_40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14742
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14742
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[350:4742]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      351..4742
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14742
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14742
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             2..145
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="NSIPFEDSGIFPGKRKMLLKARNSKGREKAHLRRSSTDFQSEVNT
                     LF"
     CDS             complement(351..3197)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="Beta_elim_lyase (E-value: 6.5e-11,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 3.2e-179, bitscore: 586.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIKNKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3293..3673)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="GCV_H (E-value: 3.7e-48, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3744..4742)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="GCV_T (E-value: 5.9e-79, bitscore: 255.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 2.5e-23, bitscore: 72.4,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVQYTGILDEHKAVRETCGIFDISHMGQFTVAGDSAAAWLNSML
                     TNDINKLNVGQGQYSVMLNDRAGVIDDLILYRMEPETFFVVVNASKIDEDFAWLSAHQP
                     AGVTLENHSDEYVGLAVQGPECGEVFSRVIPGVELPPRNGISRISAEGTDLIVCRTGYT
                     GEDGFEFFCPAKEGVKWFEAFLGAGAKPCGLGARDSLRLEMCYPLNGSDLSPDKTPLEA
                     GLGFFCALDTDFIGSDILREQKANGLSQRLAAIEYTGKGAPPRAHYAVHVPGGEAIGEL
                     TSGVLSPSLMKGIALAYLPAAHAKVGTELEIDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4905..6026)
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVNPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVRDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(6085..7008)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_6"
                     /sec_met_domain="Peptidase_S11 (E-value: 2.4e-56, bitscore:
                     181.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGKVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGYAV"
     CDS             complement(7569..8696)
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSTVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWTGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLPPSRTTFPMRNRIVS
                     GWSCATLVVEASGRSGALITARTAAEQGRDVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCPPSGASPPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKAAHTITPLLAKMQIAGQITPDAGGYFSINSREL"
     CDS             complement(8693..9778)
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPRLEKEGSRHI
                     LMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPPEDRPGLVTS
                     VHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAISPDQYHPAY
                     SPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGIPAHAVIVGE
                     AKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKSPEAFGKSTL
                     EALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGNTAAMADLLARWHAQPPPLPRQIPSP
                     YNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9802..10932)
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MRAFFRTGHPAAGKTKLPGHGAQGIFNNRGIRSQHAGIMNKSVPP
                     TKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHLNQSLGLAQALISKAGGTVETV
                     NLQGLSLLGKIRKVVSGSDIPRPDLFISAGHATHIPLICARHHFKTRAILCMKPTLPCS
                     FFDLCLIPRHDLDSGRDYTDTNIFPTQGALHPMRPDTSVPKDTTLILIGGPSKDFDWDD
                     ESMLNQLASISIHTPGDLVLTTSRRTPDGFAEKIRTAVPELTVVPVEETRPGWVARHLA
                     HASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRKSRILSGLETLEKEGMVTGYSD
                     WKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10978..11889
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 61.1; E-value:
                     4.9e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_10"
                     /sec_met_domain="Fer4_16 (E-value: 1.7e-19, bitscore: 61.1,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEWMARSPERRTDPAEVLLGCRSVICLSYDYDSPGRRPEGEGSIC
                     LYAHGKDYHGILEEKLADLQELLSIYGGKQKGYVDSGPVMERDHAEACGLGWRGKSGLI
                     VRRKGGSRFFIATLLTTLELEPDAPVSNGCGSCCRCAALCPTGAIMGNGQVDAGRCLSY
                     WTIEHRGAIPEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGL
                     LSLDAGGFAALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHA
                     SWAVERILRRYGRHASSSGARD"
     CDS             complement(11918..12286)
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="VALTTIAVNGGQTLENGLLFTTKVTFNQNAVSGDYLNNLRELFVG
                     KLSRADVGIDACLFQDSLRSRATNSVNIRKGSLDALLVGYFCTEKACHNGLDLLAVIFL
                     CLAQSYCLGQDGYHKLRF"
     CDS             12418..12969
                     /locus_tag="ctg22_12"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAATPAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             13003..13614
                     /locus_tag="ctg22_13"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRSLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13841..14512
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_14"
                     /sec_met_domain="HAD (E-value: 2.4e-28, bitscore: 90.4,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRRHPWRRLLIFLFLACIPLYILRIWDENRMKRAYLMYLWGLPAE
                     TVREYGRKFAEMAQEWIYPELKERLAEYRKKGYLCLMVSASPSFYVKPLGELLGFDEIL
                     GTDVLLEERMPAMPKLPNGNNKGAVKVERLRERNVLPEHGVLENAVAYSDSAADLPMLL
                     SCRRRVLVNPSPALKEDRLLDGAECLYPARPWKGRFGKIWRIGFFVMGLVDVNNVKSMT
                     C"
ORIGIN
        1 gaattccata ccctttgagg atagcggaat cttccctgga aaaagaaaga tgctgttgaa
       61 ggccaggaac agtaagggca gagaaaaagc tcatctgaga cgtagctcaa cggatttcca
      121 atccgaagtc aacactctat tttgagaaca aatgggtcat caaaatgaaa ggggaggaaa
      181 agcggggtgg gagaaatgtt ccttttttct ttttcaaccc atattgcttt tgggcttaat
      241 tgttttctgg atatgtttgc tctttcggat tggaaatccg attcttgaac ataagaaaaa
      301 ggctgctcca aatgaatgga acagcctttt tgaaaggaag gatgagattt ttataactct
      361 acggccttgg agaattcctc caccgtgtcg caggtgcaga ccagattgcg gtctccgtac
      421 acattatcca cccggcctac atacggccag aatttgtgaa taaggagacc ggagaccgga
      481 taagccgctt cactgcggga gtaggggtgc cgccattcgt cggcggagac catttctgcg
      541 gtatggggcg agtttttcag gacgttgtct tccttgtctg ccgtaccgtt gataatggcc
      601 gtgatttccg catgaatgcg ttccatggct tcaatgaagc ggtccagttc ttttttgggt
      661 tccgattccg tcggctccac catcagggtg cccggaacgg ggaaggacat ggtggggccg
      721 tggaagccgt agtccatgag ccttttggca atgtcatcca ccgtgaggcc ggcgtcatga
      781 gtgagctggc gcggatccag aatgcattca tgcgccacca gccccttgtt gccggagtag
      841 agaaccggga agagatgtcc gagtttcttg gcaatgtagt tggcgttaag gatggccatt
      901 tccgtggctt ccctgaggcc gtccggcccc atcatggaga ggtacatcca gcagatggcg
      961 gcgatggagg cgcttcccca cgccgcagac gctacggccc cttcttcatg gcccagcgtg
     1021 aggtgcccgg gcaggaaggg tacgaggtgt tccgctacgc cgatgggccc gatgccggga
     1081 ccgccgccgc cgtgcggcat ggcaaaggtt ttatgcaggt tcaggtggca gacgtccgcg
     1141 ccaatgcagc cggggcaagt cagacctacc tgggcattca tgttggcgcc gtccatgtac
     1201 acctggccgc cattggcatg gacgatgtcg cagagttcct tgattgtctg ttcatatacc
     1261 ccgtgcgtgg aggggtacgt gaccatgatg caggagagat tgtccttatg ggcttccgcc
     1321 tgggatttca ggtctgccat gtcgatgttg cctctttcgt cgcatttgac gggcaccacc
     1381 ttgaggccgg ccatggcgga ggatgcggga tttgttccgt gggcggaggt gggaatgagg
     1441 cagacattgc ggtggccttc tccggcgtgc ttctggtagc ggcggatggc cagtagcccg
     1501 gcatattccc ctgcggcgcc ggcgttgggc tggagggata cggcggcaaa gccggtgatt
     1561 ttcgccagac ggtcggacag gacggagagc atttcccgga tgccttccga ctggtccgcc
     1621 ggaacaaagg gatgcaggga gttggcttcc ggccacgtga tgggaatcat ttcagaggcg
     1681 gcgttcagct tcatcgtgca ggagcccaga gggatcatgg cttcatttag agccaggtcc
     1741 cgggattcca ggcggcggat gtagcgcatc atttccgttt cggaatggta ggagttgaaa
     1801 gccttttccg tgcagaaagg cgtctggcgc gtgtggacgg gatcccaggc aggagcgtcg
     1861 caatcgcagg cagcggatgt ttccgcacct gcaagggcgg aggccagtgc cgctatatcc
     1921 gcacaggttg cggtttcatc cagagagatg gctgcgtggt cggcatccac cctgcggatg
     1981 ttgtacccgg cttccagggc tttttgcacc atggcgtccg cttgtccggg aacggacagc
     2041 agcagggtgt caaagaagtt tttgttttta atggcgatgc cggcttccgt gagcgccttg
     2101 tacaggcttt tggttttcaa gtggatttcc gtgccgatgc gtttgaggcc ttcctgtccg
     2161 tggtatacgg cgtaaaaggc ggcaagcacg gccaggagca cctgggcggt gcagatgttg
     2221 gaggtcgcct tgtcgcggcg aatatgctgt tccctcgttt gcagggccag gcggtaggcc
     2281 gggcggccca gggtatctat ggacatgccg ataaggcggc cgggcatgcg gcgtttgaga
     2341 gcgtccgtgc aggacatgta ggcggcatgg gggccgccga agcccattgg gatgccgaag
     2401 cgctgcgtgt tgccgatgca gatatcggct ccgaaggcgc cgggttcccg gatgacggta
     2461 agggccatga gatccgccgc cacgacgcag agcgcgcccg tggcatgcac gcgggaaaag
     2521 aagtccgtgt agtcgcagat gcggccgagc gtgtccggat attggacaag cactccggcc
     2581 agatccgcac cgatggatgc ggggtcaaag gatgagcaat ctcccacgat gatgttaacg
     2641 ccctggaagg cggcgcgggt acggatgacg ctgatggtct ggggatggca ggtgtccgcc
     2701 acaaagaagg tgtttgcttt ggggcgcgcg ttccggcaca tggtgacggc ttctgctgct
     2761 gcggtgcctt catccagcag ggaggcgttc gctaccggca gccctgtcag ggaagagacc
     2821 atggtctgga aattcatgag catttccagc cgtccctggg cgatttccgg ttgataaggg
     2881 gtgtaggccg tgtaccagcc ggggttctcc agtacattgc ggaggatgac ggagggagtg
     2941 atggtgccgt aatagccctg gccaatgaag gttttcagga gcttgttttt ccgcagaatg
     3001 gaacggagtt cctccagggc ttccgtttcc gatttggctg cgggcaggtc cagcggggcc
     3061 ttcatgcgga tatctgcggg gacgatgtcc gcaatgagtt cgtcaagcgt ccggtagccg
     3121 aggctgtcaa gcatttcccg gcgttcttcc ccctgggggc cgatgtgccg gctggcaaaa
     3181 tctgagtggg tattcatgtg gtatctctgg ctggtaatag cgtccggccg cgggacgggc
     3241 caaacaaaat gccccgggat ggaatcaccg gggcggggga ggaaagaatg gttcaggagc
     3301 agtattcctc gtaatccgtg gcgttcatca tatcttccgt ttccgtggga acgtccaggc
     3361 ggattttgta cagccagcct gcgccgtagg ggtcggagtt aatgagggag gggtcattgg
     3421 aaagctcttc attcacttcc aggatttctc ctgaaacggg ggtgtacacg tcgctggcgg
     3481 ctttgacaga ttccacgacg gcgacggggt cgccggccgc gacggtggcg cctacttcgg
     3541 gaaggtctac aaagacgaca tcggagagtt cggcctgggc atggtctgaa atgccgatgg
     3601 tgccgatgtc cccgtcaatt tcaatccatt cgtgatcctt ggaatacagc agattttctg
     3661 gtacgtcgtg cataagatgt aattgtttga agtgagagtg tagtaaaatg aggtgtttgt
     3721 cagtttattt ttgcgccgtc gtgtcagcct tttttataaa agggtttttt tacgaccacg
     3781 gccggaaatt tccttcccct tacgtcaatt tccagctccg tgccgacctt ggcatgggcg
     3841 gcaggcaggt aggccagggc aatacccttc atcagcgaag gagagagcac gccgctggta
     3901 agttctccga tggcttctcc gccggggacg tgaacggcat aatgggcgcg gggaggggct
     3961 cccttgccgg tgtattcaat agccgccagc cgctggctga gaccgttggc tttttgttcc
     4021 cggaggatat cggaaccgat gaaatccgta tccagcgcgc agaagaagcc gagcccggct
     4081 tccagaggcg tcttgtccgg agagaggtcg gagccgttca gaggatagca catttccaga
     4141 cgcagactgt cgcgggcgcc caggccgcag ggtttggctc ctgctccaag aaaggcttca
     4201 aaccatttga cgccttcctt agccgggcag aagaattcaa aaccatcttc cccggtatag
     4261 ccggtgcggc agacaatgag atccgtccct tccgccgaga tgcgggaaat tccattgcgg
     4321 gggggaagtt ccacaccggg gatgacgcgg gagaatactt ctccgcattc gggaccttga
     4381 acagccagcc ccacgtattc gtcggagtgg ttttccaggg ttacgcctgc aggttgatgg
     4441 gcggaaagcc atgcgaagtc ttcatcaatc ttggaggcgt tcaccactac gaagaaggtt
     4501 tccggttcca tccggtacag gataaggtcg tcaatgactc cggctctgtc attgagcatg
     4561 acggagtatt gcccctgccc tacattcaat ttgttgatgt cattggtcag catggagttc
     4621 agccaggccg cggcagaatc gccggctacc gtgaactgcc ccatgtggga gatgtcaaag
     4681 atgccgcagg tttcgcgcac tgctttgtgt tcgtccagaa tgccggtgta ctgcaccggc
     4741 atattccagc cggcaaaagg aaccattctg gctcccagtt caacgtgttt agctgccagg
     4801 ggggtggatt tgacgtctgt atcagtcatg aggcgatgtg aaggttgtga gcaatctgct
     4861 ccttatatca gtaaaagtca atggaattcc ggtaacgctt ccgtctagac attgaagcgg
     4921 aattcgataa cgtccccgtc tttgacgaca tattcttttc cttcgatgcg cagcttgccg
     4981 tgttccctcg ctccggcctt gccgccacag gaaaccaggt cgtcgtagtg cactacctct
     5041 gcggcgataa aaccgcgttc aaagtccgtg tggataacgc cggccgcctg aggtgctttt
     5101 gccccggacg gaatggtcca ggcccgcgtt tccttgattc ccgtggtgag gtaggtgcgc
     5161 aggcccagaa ggtggtacac ggcccggatg aggtcggaaa cgccggaatc ccgcacgccc
     5221 agggattcca gaaattcgcg ggattcttcc tccgagacgt cgatgagttc ctcttcaatc
     5281 cgggcagaga tgacaatggc ttccgcgttg tggtgttccg ctacgtattt tttcacctgg
     5341 gagacgtagg gatgggcgtc cgggttggag atggcgtccg ccagttcgtc ttcattgaca
     5401 ttgcaggcga aaatgctttt tttatccgaa agcagctgga aggaatggag cagcttgcgt
     5461 tcatcgtcgt ccagctgcgg ttcaagggtg agggcgggat tgccttcgtt caggtggggc
     5521 aggagtttgg tgatgagggc cacttcggcc ttggcttcct tgtcgccgct gcgtgccttg
     5581 cgttcgcggg aagagagtct cttttccatg gtggcgatat ccgccagaat gagttccgag
     5641 ttgatgatgt caatgtcgcg cagaggattc acggaaccga gttcatgaat gatatcatca
     5701 ttgtcaaagc agcggactac ctgcacgatg gcgtccactt cacgaatgtt cgccagaaac
     5761 tggttgccca ggccggcgcc ttccgaggcg cccttgacca ggccggcaat atccacgaat
     5821 tcaataagcg tggggatgat tttttcagaa ccggacatgt cggaaagaac ctgcaggcgg
     5881 ggatccggga ctgttaccat acccacgttc gggtcaatgg tgcagaaggg atagttggcc
     5941 gcctgggcct tgcgcgtccg ggtgaccgca ttgaatagag tggatttgcc gacgttgggg
     6001 agacctacaa tacctgcctg taacataggc aggactgata gcgggtcacg ccgtgaaagt
     6061 caaataccaa ttgccgacgg gcatttatac ggcgtatccc agagcccatc tgatcaggtt
     6121 ttccgattcc gtccagatac gggacggatg gcagccgagg acgacgacga tgacatggcg
     6181 cccgttgacg ccggctgagg aaaccaggca gcgtccggcg gcgttcgtgt atccagtttt
     6241 catcccggta acccaggggt tctgggtgag cagcttgttg gtgtttctca acagaagcgt
     6301 tctgccgttg gcgcgggtaa aggcatattg gcgtttgcag ataatattgc gcagttccgg
     6361 gttgcggtac acgtaatagg cgcagcgggc catgtcaatg gcagtggaat attgatctgc
     6421 cgggaggccg ttgggattgg cgaagcgtga gttgtacatg cccatctgcc gggctttggc
     6481 attcatcaac tgggcgaaac ggggaacgga acccgccgta tcgcgggcca gcgccagggc
     6541 tacgtcgttg aaactgcgga tcatcatggc attgagcagt tcgcggcgtg aatagacttc
     6601 ccccgcccgg aatcccagtt tggtggggtc cgccttggta tcggaaggct ggatgaccac
     6661 ttttttgtcc aggctgccgt gttccatcac gaccatggct gtcacgagtt tctgcgtgct
     6721 ggctacctgg cggtgctgga ggccgttgtg ggaaaagagc actttgccgg taagggcgtc
     6781 catgacgcag gcactggcgc agcggggcgt gcgcggggcg cttgagggga tggctacagg
     6841 gcgtgtgggg aaattggccg gtcgggggag ggcatgggaa accggctggg agagttgtgg
     6901 gggaacgggc gttgcgaggg ggatgtagtc acttgaatcc ccgtacgatt ggcagcttgt
     6961 ggagctcagg caaagggaga atcctgcaag aagggcgaat aaacgcatgt cttgttgcta
     7021 cagtaagaag tttcgttcat caagcccaaa ctccgcattt gaaagagagc cggacgaaaa
     7081 aggccgcgga tcggataatc cgcggccttt tttctctatt aactacctat ggaaccaaaa
     7141 accaccctga acggattttg aattgctttt tccatccgtc ggacagatct tgtgaaggat
     7201 gagactccag acaggagaga tgcgttcaaa atatgttcgt caacagttct ttttaagagg
     7261 tgttgccgta tgcgcccgag cctgtgtccc gtaaatatag cagagatttt ttccgaacat
     7321 attttgtttt tcgcgggcat gtaaattttg ccgcagacat ttaaaatgcc ggggatgtcc
     7381 tgacgatata tttaattttt ggaataaaat tattgaagga gaggatttgg tgactgtttt
     7441 aagacgtttt tttgcatccg gatggaaagg tttttatacg ggagatggac ggcgctccct
     7501 tccggttcca tggtcaggga gaggaggccc ggacctggcg ttttccccgg cggaaaagcg
     7561 gaatcttcct aaagttccct gctgttaatg gagaaatacc ctccagcgtc cggagtaatt
     7621 tgccctgcaa tttgcatttt ggccaaaagc ggggtgatag tatgcgccgc ttttcccaga
     7681 gaggtgcaga gggtgtcaat agtattgaaa cccagtctga tggcgtggag aatctccttt
     7741 tcttccaaag tgggaagcgg tgggggtgag gctccggaag ggggacatgg cgagaagaga
     7801 ggcagtccct gttccggaac ggcccagttc atgtcctgca gaatatcgga ggctccggta
     7861 gccaggatgg ctccgtcccg gatgagggca tggcatccgt cggaagaatg ccggtcaacc
     7921 ggtccgggaa tgcaaaaaac gtctcggccc tgttcggccg ccgttcgggc cgtgatcaag
     7981 gctccgctgc gtccggacgc ctccaccacc agcgtagcgc agctccagcc gctcacgatg
     8041 cggttgcgca tgggaaaagt ggtgcgggaa gggggcaagt ccatcgggaa ctcggagact
     8101 accgctccat gcccgtccgc aatgcgctgc gccaaatttc tgttttcccg aggatacagt
     8161 ttgttgagtc ctgctccgat aacggcgatg gtgcgcccct ccgcgtccat ggccccggta
     8221 tgggcttccg tgtccacgcc gcgcgccagt ccggaaatga cggtgactcc ggcttccgcc
     8281 aggtcatggg agatgtttct ggcgcaaagc ctgccgtaat gggtggccat ccgtgagccg
     8341 acgacggcaa tggagcgttc ggcatccgtt ccggtccagt ttccccagga gtagaggaca
     8401 atgggcgggt ctgggagagc acgcagggag gatgggtagg agtcgtcaaa aaccgtggtt
     8461 accgcggccc ccgcgttatc cgccagttcc agttccctgt acgggttgac ggtactccgc
     8521 caagaggaaa tgcggcaagc cagctgcgcc cccacgccgg gaatttccat caacagggag
     8581 gaaggggatt ccagaatcag ttccggagag gcgaatacct gcaggagacg catgattctg
     8641 acagggccca ggcccggtat caggttcagg gctatggctg cttcccgggg tgtcatgaat
     8701 aaggggtcag ttcctggtaa acgtccagat gggcttgaat catatcctgc atattgtaag
     8761 gggaaggaat ttgccggggc aggggggggg gctgggcatg ccagcgggcc agcaggtccg
     8821 ccatggcggc ggtatttcct acggcgacgt tcccttcagg aaggaaggcg tccagctgtt
     8881 ccttgactcc gccgtgagcg tatccggcca cgggcttgcc cagggcgagc gcctccaggg
     8941 ttgatttgcc gaaggcttcc gggcttttgg tcagggagag ggtgacggaa catgtggaaa
     9001 ggatttccct tagatcctgg cgatggcctg tccaggtgaa ggactgggag acgccggaac
     9061 gttctattgc ccgcaggacc tcgtttttat attcttcttt tcccttcttt gcttctccta
     9121 caatgacggc gtgggccgga attccctgtt ccagaagctg cctgacgacc ggaatcagat
     9181 ccagatgccc tttcaggcgc gtgatgcggc ccggcaggca cagggtgaat ttccccttca
     9241 gttcaggata ggacatgaac cagcccgtga gccattcccg ggagggggag taggccgggt
     9301 gatattggtc cggggaaata gcattgggta tgattctgat atggtccgga ggggtggacg
     9361 gataatggtc aaggatgtag tccctgatgc agttggagac ggcgatcacc ctctctcccc
     9421 ggctcatgat ggcggagtac cgattgacgg agtagaagcc gtgaacgctg gtgacgaggc
     9481 cgggacggtc ttccggcggg agctttttcc atgccaagta gcctgcccac gcaggaacgc
     9541 gggaatggag atgcaggata tccggtctga cggcctgaag cagggcgcgg agggccccga
     9601 tgcggaagag agtggagatg ctttttttgc ctatcggcat caggatgtgg cgggagcctt
     9661 ccttttccag acggggcacc aggcgtccgc ctccggaaac gacgatattt tccacgcccc
     9721 gggaagaaag gccgctgccc agttccataa cgacttgttc cacgcctccg gattccatgg
     9781 aggggacgag atgtactatt ttcataaggc gcggagctga gggaaaaatc tggagaggat
     9841 gtagtctgct gcacggtccg cttccagaag cggggaaccg ggagccgtca ggcggaagtt
     9901 ctgttttttc cagtcactgt atccagtaac catgccttcc ttttccagtg tctccaggcc
     9961 ggacaggatg cgggatttgc ggctgccatg tcggcgcggt acggaaagga tgcctacagg
    10021 agcgccggag ccaagagcct catataccat ggagacgctg tcctggctga cccaggcggc
    10081 ggaggcgtgc gccagatgcc gggctaccca ccccggccgg gtttcctcca cgggaacaac
    10141 ggttagttcc ggaacggccg tccggatttt ttccgcaaag ccgtccggcg tccggcgcga
    10201 ggtggtcaga acgaggtctc cgggggtgtg gatgctgatg gacgcgagct ggttgagcat
    10261 gctttcgtca tcccagtcaa aatctttgct gggtcctcct atgagaatca gtgtggtatc
    10321 ctttggtacg gaagtatccg gtctcatggg gtggagagct ccctgggtag ggaagatatt
    10381 cgtatccgtg taatcgcggc cggaatccag gtcatggcgg ggaataaggc agaggtcgaa
    10441 aaaggagcag ggaagcgtgg gcttcatgca gaggatggcc cgggttttga aatggtgccg
    10501 cgcgcagatg agcgggatat gcgttgcatg tccggcggaa atgaacagat ccggccgtgg
    10561 aatgtcgctg cctgagacga ccttccggat tttccccaaa agggaaagcc cctgcaggtt
    10621 caccgtttcc acagttcccc ccgctttgga gatcagagct tgcgccagcc ccagggactg
    10681 gttgaggtgg ccctgtttcc catcgctcag aatccggatg ttcatatatg cggcattatg
    10741 aagcggcggc ggggtgcagg caatccaatt tccaccggac agaagaaaat tcttggtggg
    10801 aggcacgctc ttgttcatga ttccggcgtg ctgactccgg attcctctgt tattaaagat
    10861 tccttgtgcg ccgtgtcccg gcagcttggt ttttccggct gccgggtggc ccgtgcggaa
    10921 aaaagcccgc atgcggaaaa attgtttcaa tggctggagc gcggatggca cgccgggatg
    10981 gagtggatgg cgcgttcccc ggagcggcgc acggatcctg cggaagtgct tctcggatgc
    11041 cgttccgtca tctgcctgtc ctatgattat gacagccccg gtaggcgtcc ggagggggag
    11101 ggaagcattt gcctttacgc ccatggaaag gattaccacg gaattctgga ggaaaaactg
    11161 gcggatttgc aggagctgct ttccatttac ggcgggaagc agaaggggta tgtggactcc
    11221 ggccccgtta tggaacggga ccatgcggag gcctgcggcc tgggctggcg cgggaaaagc
    11281 ggtctgatcg tgcgcaggaa agggggctcc cgctttttta tcgctaccct gctgactacg
    11341 ctggaactgg aaccggatgc tccggtttca aacggatgcg gcagttgctg ccgttgtgcg
    11401 gccctgtgtc cgacgggcgc aattatggga aacggtcagg ttgatgccgg acgctgcctt
    11461 tcctactgga cgattgaaca ccggggggct attccggaag aaatccgtcc cctgataggc
    11521 acgcgcctgt acgggtgcga tacctgcgtg acggtctgtc cctggaacgg taagcctttg
    11581 ccggatgttg acgaacggtt ccgcatgtcc cgtctgctgg cttccattcc cctgcgcggt
    11641 cttctttccc tggatgccgg cggttttgcg gccctgttcc ggaattcccc gttgaaaagg
    11701 ctcaagaggg aagggctgct gcgtaacggc tgcgttgtgc tggggaatgc ggggactccg
    11761 gatgacattg attttctgaa ggcgctttac ggggagtctc ctctggtgga ggaacacgct
    11821 tcctgggctg tggagcgcat cctccgccgc tacgggcggc atgcatcttc aagcggtgca
    11881 agagattaaa aatagaaaaa atgatgtttt ggtcttgtca aaacctcaat ttatggtatc
    11941 catcttgccc caagcaatag ctctgcgcga ggcagagaaa aataacagct agcaaatcca
    12001 atccattatg gcacgccttt tcggtacaga aatacccaac gagaagcgca tcgaggcttc
    12061 ccttccgtat atttacggaa ttggtcgctc gacttctaag agaatcctgg aacaagcagg
    12121 catcaatccc gacatccgca cgggacagct taccgacgaa cagctcacga agattgttca
    12181 agtaatcacc actgacggca ttttgattga aggtgacctt cgtcgtgaaa agcaatccat
    12241 tctcaagcgt ctgacctcca ttaactgcta tcgtggtcag cgccaccgcc gcggccttcc
    12301 ggtacgcggc cagcgtaccc gtacgaatgc ccgcacccgt aaaggcaaga agaagactgt
    12361 tggcgcgcag gccaagaaga agtaatccgc caatctgaat tttaatatag ctttactatg
    12421 gctagcgaag aaatcaccaa cgaaaccgcc gaacagcctg tggaagcggc aactcccgct
    12481 cccgtcgctg aaactccggc cgccgctgtt tccgctcctg aagaaatcaa gaagcccgaa
    12541 ccccgcaagg acatctttgc ggaacttggt ctgggcggcg atgacgacaa gcccaaaatc
    12601 ctgaaggcca agggcagcaa aaacgtttcc acgggcgtgg ttcacgtttc ctccacgttc
    12661 aacaacaccg tcgtgactgt gaccgaccag cgcggcaatg tcatcggctg gtcctccgcc
    12721 ggcaagatgg gctttaaggg ttcccgcaag agcacggctt atgccgggca ggtggtgtgc
    12781 caggacgcct gccgccaggc catgggccac ggcttgcgtg aagtggaagt gcgtgtgaag
    12841 ggccccggtt ccggtcgtga atccgctgta cgtgccgtgc agacgatcgg tattgaaatc
    12901 acctccatca aggacgtgac tcccattccc cacaacggct gccgtcctcc gaaggcccgc
    12961 cgtgtctaat tgagaatcct ttacctatag atctaatata tcatggctcg ttataccggt
    13021 ccccgcgata aagtgtcccg ccgttttggc gttgcccttt tcggttccac caaggctctt
    13081 gaaaagcgcc ccttccctcc cggccagcat ggcatgcgcg ccggccgcaa gaagaaatcc
    13141 gactatggcg tgatgcttgc tgaaaaacag aagctgcgtt tccagtacgg tgtgcttgaa
    13201 ggccagttcc gcaagtatta tgcagaagcc gcccgccgcc gcggcattac cggcgatatt
    13261 ctgcttcagc tccttgagct tcgtctggac aatgttgtgt accgcctcgg tttcagcaac
    13321 acccgcgccg gagcccgtca gctcgtttcc cacggccaca tcaccgtgaa cggcaaaaag
    13381 acgaacattg cgtcctactc ctgccgtccg ggcgatgtca ttgccgttgg cggcaaggct
    13441 tcctcccagc agctggttac ccgttccctt gacctgactc aggctactgt ggttccggat
    13501 tggctggaat gcgaccgtga caagctcacg ggcaagattg cccgcgtgcc ttccaaggaa
    13561 gagattgctc ccatcgtcaa cgagcagctc atcgtggaat tctactcccg ttaatcttta
    13621 tttccttctg gatttgcttc aaaaccccgg ttgcttttcg gcggccgggg ttttgggcat
    13681 tcagggggga gtaatggaag agttggctgt tgagagttaa gggaagcgga tataagatga
    13741 aagcatgacg gacgattgga aaaaaagagg cgcagcgctt ttcgatatgg acggaacgct
    13801 ccttccctgg gatacgcaat atgttttttc ctgttttgtg gtgaggcgcc atccttggag
    13861 acgcttgctg atttttcttt tcctggcctg tatcccgctc tatattttga gaatatggga
    13921 tgagaaccgg atgaagaggg cttatctcat gtatttgtgg gggcttcccg ctgaaacggt
    13981 gcgggaatat ggacggaagt ttgccgagat ggcgcaggaa tggatttatc cggagctgaa
    14041 ggagcggctg gcagagtatc ggaagaaggg gtatttgtgt ctcatggttt ccgcttctcc
    14101 atcattttac gtgaagcctc tgggtgaact gctgggattt gacgaaattc tgggaacgga
    14161 tgtgcttctg gaggaacgca tgccggcaat gccgaaactg ccgaacggta ataataaggg
    14221 ggcggtgaag gtggaacgtc tgcgggagcg gaatgtactg ccggaacatg gtgttctgga
    14281 aaacgccgtt gcctacagcg acagtgccgc ggatttgccc atgctgcttt cctgcaggcg
    14341 gagggttttg gtgaatcctt ctcctgccct gaaagaagac aggcttctgg atggtgcgga
    14401 gtgtctgtat ccagcaaggc cttggaaggg aaggtttggc aagatatgga gaattggatt
    14461 ttttgtcatg gggctggtgg atgtaaataa tgtgaaatca atgacttgct gatttatcaa
    14521 gagaaaattc tttacttttg tgacgaaaat gtttcacttt tcttaacaag ggggaaaaag
    14581 catttttctt tccatgttag caaatcaaca attaataccc taaccaagta atagtcatgc
    14641 aaaccaagaa catcatcagt gttgcggcag ttgtggcatc ctttgccgga gctgctcttg
    14701 cgggtactcc cgtcaagatt gttgctccga ctccggttcc cg
//
