## Fri May 2 02:40:37 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_019175405.1/GCA_019175405.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_019175405.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_019175405.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs AFLMLIMI_00001 543734.LCABL_15280 2.4e-22 93.2 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat AFLMLIMI_00002 543734.LCABL_15280 3.65e-101 301.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat AFLMLIMI_00003 543734.LCABL_15280 5.72e-45 153.0 COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,4HBUD@91061|Bacilli,3F5GQ@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain ytlR - - - - - - - - - - - DAGK_acc,DAGK_cat AFLMLIMI_00004 1423732.BALS01000152_gene507 2.23e-209 582.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_00005 543734.LCABL_21290 1.08e-48 162.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_00006 543734.LCABL_15270 1.65e-311 846.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes,4HD22@91061|Bacilli,3F5HJ@33958|Lactobacillaceae 91061|Bacilli S Sterol carrier protein domain - - - - - - - - - - - - Acetyltransf_9,SCP2_2 AFLMLIMI_00007 543734.LCABL_15260 0.0 1585.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F44X@33958|Lactobacillaceae 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 AFLMLIMI_00008 543734.LCABL_15250 1.62e-151 426.0 COG0457@1|root,COG0457@2|Bacteria,1VFGR@1239|Firmicutes,4IBSH@91061|Bacilli,3F4MD@33958|Lactobacillaceae 91061|Bacilli S repeat protein - - - - - - - - - - - - TPR_12,TPR_16,TPR_19,TPR_2,TPR_8 AFLMLIMI_00009 543734.LCABL_15240 4.69e-159 445.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F3U3@33958|Lactobacillaceae 91061|Bacilli G phosphoglycerate mutase pgm6 - - - - - - - - - - - His_Phos_1 AFLMLIMI_00011 543734.LCABL_15230 6.48e-311 847.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,3F4N5@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans AFLMLIMI_00012 543734.LCABL_15220 0.0 1513.0 COG0178@1|root,COG0178@2|Bacteria,1TR1H@1239|Firmicutes,4H9RE@91061|Bacilli,3F50Y@33958|Lactobacillaceae 91061|Bacilli L ABC transporter uvrA2 - - - - - - - - - - - ABC_tran AFLMLIMI_00013 543734.LCABL_15210 2.45e-75 225.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli,3F7E3@33958|Lactobacillaceae 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 AFLMLIMI_00014 543734.LCABL_15200 8.05e-278 759.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,3F3RF@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 AFLMLIMI_00015 543734.LCABL_15190 1.87e-157 442.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli,3F4HE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 AFLMLIMI_00016 1423732.BALS01000015_gene1677 1.42e-39 132.0 2A67P@1|root,30AP5@2|Bacteria,1U6XT@1239|Firmicutes,4IGS2@91061|Bacilli,3F8PG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00017 543734.LCABL_15170 1.24e-122 350.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,3F53J@33958|Lactobacillaceae 91061|Bacilli L ADP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX AFLMLIMI_00018 543734.LCABL_15160 2.8e-151 426.0 COG4915@1|root,COG4915@2|Bacteria,1VB0U@1239|Firmicutes,4HMAQ@91061|Bacilli,3F7AZ@33958|Lactobacillaceae 91061|Bacilli S 5-bromo-4-chloroindolyl phosphate hydrolysis protein - - - - - - - - - - - - Halogen_Hydrol AFLMLIMI_00019 543734.LCABL_15150 7.29e-270 741.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,4H9Z6@91061|Bacilli,3F5KJ@33958|Lactobacillaceae 91061|Bacilli P Toxic anion resistance protein (TelA) yaaN - - - - - - - - - - - TelA AFLMLIMI_00020 543734.LCABL_15140 0.0 913.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator ydiC1 - - - - - - - - - - - MFS_1 AFLMLIMI_00021 543734.LCABL_15130 5.93e-207 573.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 AFLMLIMI_00022 543734.LCABL_15120 4.62e-48 153.0 COG1278@1|root,COG1278@2|Bacteria,1W688@1239|Firmicutes,4I1Y3@91061|Bacilli,3F81I@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD AFLMLIMI_00023 543734.LCABL_15110 0.0 1899.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli,3F3X4@33958|Lactobacillaceae 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS AFLMLIMI_00024 543734.LCABL_15090 8.49e-120 349.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HJYN@91061|Bacilli,3FC2J@33958|Lactobacillaceae 91061|Bacilli D DivIVA protein divIVA - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA AFLMLIMI_00025 543734.LCABL_15080 9.78e-185 513.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,3F48W@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein ylmH - - - - - - - - - - - S4 AFLMLIMI_00026 543734.LCABL_15070 6.52e-59 182.0 COG0762@1|root,COG0762@2|Bacteria,1VEKA@1239|Firmicutes,4HNJR@91061|Bacilli 91061|Bacilli S integral membrane protein ylmG - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT AFLMLIMI_00027 543734.LCABL_15060 7.24e-102 295.0 COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,4HKIC@91061|Bacilli,3F7MQ@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0051301,GO:0071840,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF AFLMLIMI_00028 543734.LCABL_15050 3.25e-291 796.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,3F4V1@33958|Lactobacillaceae 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin AFLMLIMI_00029 543734.LCABL_15040 1.44e-311 850.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli,3F413@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA AFLMLIMI_00030 543734.LCABL_15030 3.57e-201 557.0 COG1589@1|root,COG1589@2|Bacteria,1V6V5@1239|Firmicutes,4HDFD@91061|Bacilli,3F406@33958|Lactobacillaceae 91061|Bacilli D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 AFLMLIMI_00031 543734.LCABL_15020 4e-259 710.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,3F4FW@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 AFLMLIMI_00032 543734.LCABL_15010 0.0 916.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli,3F49W@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M AFLMLIMI_00033 543734.LCABL_15000 1.33e-230 635.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli,3F3YP@33958|Lactobacillaceae 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 AFLMLIMI_00034 543734.LCABL_14990 0.0 1324.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli,3F47N@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase AFLMLIMI_00035 568703.LGG_01279 1.6e-68 208.0 COG4839@1|root,COG4839@2|Bacteria 2|Bacteria D cell division protein FtsL ftsL - - - - - - - - - - - DivIC AFLMLIMI_00036 543734.LCABL_14970 6.77e-219 604.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,3F3MF@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 AFLMLIMI_00037 543734.LCABL_14960 1.61e-101 293.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,3F6K3@33958|Lactobacillaceae 91061|Bacilli K Belongs to the MraZ family mraZ GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - ko:K03925 - - - - ko00000 - - - MraZ AFLMLIMI_00038 1423732.BALS01000025_gene2376 7.11e-60 186.0 29Q7N@1|root,30B6Q@2|Bacteria,1U7MX@1239|Firmicutes,4IHJ5@91061|Bacilli,3F9XF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00039 543734.LCABL_14930 0.0 932.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F542@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N AFLMLIMI_00040 543734.LCABL_14920 2.32e-193 536.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,4HF14@91061|Bacilli,3F3WC@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 AFLMLIMI_00041 543734.LCABL_14910 3.29e-146 412.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HE6M@91061|Bacilli,3F4GP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AFLMLIMI_00042 543734.LCABL_14900 4.79e-142 402.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli,3F3VF@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AFLMLIMI_00043 543734.LCABL_14890 8.63e-182 506.0 COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,4HB2F@91061|Bacilli,3F3U8@33958|Lactobacillaceae 91061|Bacilli D Belongs to the ParA family minD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03609 - - - - ko00000,ko03036,ko04812 - - - AAA_31,CbiA AFLMLIMI_00044 543734.LCABL_14880 1.56e-147 416.0 COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,4HBTI@91061|Bacilli,3F61V@33958|Lactobacillaceae 91061|Bacilli D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC GO:0000910,GO:0003674,GO:0004857,GO:0007049,GO:0007105,GO:0008150,GO:0009987,GO:0022402,GO:0030234,GO:0031333,GO:0032271,GO:0032272,GO:0032506,GO:0043086,GO:0043254,GO:0044087,GO:0044092,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0065009,GO:0098772 - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C AFLMLIMI_00045 543734.LCABL_14870 2.48e-112 323.0 COG2891@1|root,COG2891@2|Bacteria,1VEV7@1239|Firmicutes,4HPAC@91061|Bacilli,3F6PG@33958|Lactobacillaceae 91061|Bacilli M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD AFLMLIMI_00046 543734.LCABL_14860 1.88e-191 533.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3F3MC@33958|Lactobacillaceae 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC AFLMLIMI_00047 543734.LCABL_14850 4.82e-229 632.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F3ZV@33958|Lactobacillaceae 91061|Bacilli D cell shape determining protein MreB mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl AFLMLIMI_00048 543734.LCABL_14840 1.97e-152 429.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,3F5IM@33958|Lactobacillaceae 91061|Bacilli L DNA repair protein radC - - ko:K03630 - - - - ko00000 - - - RadC AFLMLIMI_00049 543734.LCABL_14830 1.98e-148 418.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 AFLMLIMI_00050 543734.LCABL_14820 7.32e-307 836.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli,3F498@33958|Lactobacillaceae 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M AFLMLIMI_00051 543734.LCABL_14810 0.0 1793.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,3F3RB@33958|Lactobacillaceae 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 AFLMLIMI_00052 543734.LCABL_14800 1.24e-148 419.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F676@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N AFLMLIMI_00053 543734.LCABL_14790 1.17e-286 783.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli,3F3N0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI AFLMLIMI_00054 543734.LCABL_14780 6.1e-272 746.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class V iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 AFLMLIMI_00055 543734.LCABL_14770 0.0 1036.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli,3F47K@33958|Lactobacillaceae 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA AFLMLIMI_00056 543734.LCABL_14760 7.1e-111 318.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,3F6NT@33958|Lactobacillaceae 91061|Bacilli T GAF domain-containing protein yebR - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 AFLMLIMI_00057 543734.LCABL_14750 5.31e-143 403.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli,3F3P0@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 AFLMLIMI_00058 556268.OFAG_00391 1.86e-100 347.0 COG1204@1|root,COG1204@2|Bacteria,1PG9I@1224|Proteobacteria,2WCVD@28216|Betaproteobacteria,4789R@75682|Oxalobacteraceae 28216|Betaproteobacteria L helicase superfamily c-terminal domain - - - - - - - - - - - - DEAD,Helicase_C AFLMLIMI_00059 1212548.B381_01799 7.19e-29 118.0 2C2MI@1|root,2ZBMN@2|Bacteria,1RAX0@1224|Proteobacteria,1S35B@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Domain of unknown function (DUF1837) - - - - - - - - - - - - DUF1837 AFLMLIMI_00060 568703.LGG_01253 3.12e-90 268.0 COG1476@1|root,COG1476@2|Bacteria,1V8IM@1239|Firmicutes,4HQD4@91061|Bacilli 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 AFLMLIMI_00061 543734.LCABL_14570 0.0 1377.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,3F415@33958|Lactobacillaceae 91061|Bacilli K Tex-like protein N-terminal domain protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF AFLMLIMI_00063 1133569.AHYZ01000076_gene68 2.51e-62 191.0 COG3041@1|root,COG3041@2|Bacteria,1TUTW@1239|Firmicutes,4IGG3@91061|Bacilli,3F88F@33958|Lactobacillaceae 91061|Bacilli S ParE toxin of type II toxin-antitoxin system, parDE - - - - - - - - - - - - YafQ_toxin AFLMLIMI_00064 543734.LCABL_14520 3.52e-57 177.0 COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,4HR7A@91061|Bacilli,3F7DM@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - ko:K07473 - - - - ko00000,ko02048 - - - RelB AFLMLIMI_00065 543734.LCABL_14510 4.74e-135 383.0 COG0454@1|root,COG0456@2|Bacteria,1U91G@1239|Firmicutes,4IJ1J@91061|Bacilli,3F938@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 AFLMLIMI_00066 543734.LCABL_14500 1.09e-133 382.0 2C09S@1|root,30187@2|Bacteria,1U5GF@1239|Firmicutes,4IF7A@91061|Bacilli,3F5VJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function C-terminus (DUF2399) - - - - - - - - - - - - DUF2399 AFLMLIMI_00067 543734.LCABL_14490 1.1e-62 192.0 2EJFD@1|root,33D6D@2|Bacteria,1U38N@1239|Firmicutes,4HRYN@91061|Bacilli,3F8AW@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2568) - - - - - - - - - - - - DUF2568 AFLMLIMI_00068 543734.LCABL_14480 1.41e-84 250.0 COG0789@1|root,COG0789@2|Bacteria,1VKCY@1239|Firmicutes,4HSCZ@91061|Bacilli,3F88Z@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 AFLMLIMI_00069 543734.LCABL_14470 2.98e-272 749.0 2DKMH@1|root,309XQ@2|Bacteria,1U5WE@1239|Firmicutes,4IFK1@91061|Bacilli,3F6MD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00070 543734.LCABL_14460 1.63e-201 559.0 COG1131@1|root,COG1131@2|Bacteria,1TRM5@1239|Firmicutes,4HFBN@91061|Bacilli,3FC3M@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yvfR - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00071 543734.LCABL_14450 1.17e-169 475.0 COG0842@1|root,COG0842@2|Bacteria,1V7QG@1239|Firmicutes,4HFU4@91061|Bacilli,3F5Q7@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter XK27_09830 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 AFLMLIMI_00072 543734.LCABL_14440 9.9e-264 723.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli,3F3VR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 AFLMLIMI_00073 543734.LCABL_14430 2.07e-135 384.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli,3F4VH@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg AFLMLIMI_00074 543734.LCABL_14420 3.99e-197 547.0 COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,4HD8F@91061|Bacilli,3F572@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 degV - - - - - - - - - - - DegV AFLMLIMI_00075 543734.LCABL_14390 1.02e-113 325.0 COG0454@1|root,COG0456@2|Bacteria,1UI2W@1239|Firmicutes,4ISXQ@91061|Bacilli,3F8D7@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 AFLMLIMI_00076 543734.LCABL_14380 7.91e-202 559.0 COG0454@1|root,COG0456@2|Bacteria,1V7Z2@1239|Firmicutes,4HPF8@91061|Bacilli,3F7HG@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 AFLMLIMI_00077 543734.LCABL_14340 1.51e-146 413.0 COG0702@1|root,COG0702@2|Bacteria,1V7A7@1239|Firmicutes,4HIII@91061|Bacilli,3F63T@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding - - - - - - - - - - - - NAD_binding_10 AFLMLIMI_00078 543734.LCABL_14330 1.07e-72 218.0 COG0599@1|root,COG0599@2|Bacteria,1VWSB@1239|Firmicutes,4HJ1V@91061|Bacilli,3F736@33958|Lactobacillaceae 91061|Bacilli S decarboxylase yphJ - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD AFLMLIMI_00079 543734.LCABL_14320 1.84e-100 290.0 COG1917@1|root,COG1917@2|Bacteria,1V3TP@1239|Firmicutes,4HWR6@91061|Bacilli,3FBIH@33958|Lactobacillaceae 91061|Bacilli S Cupin domain yphH - - - - - - - - - - - Cupin_2 AFLMLIMI_00080 543734.LCABL_14310 1.71e-206 571.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_00081 543734.LCABL_14300 1.8e-142 406.0 2EGU7@1|root,33AKD@2|Bacteria,1VMES@1239|Firmicutes,4HXVU@91061|Bacilli,3F7PT@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 AFLMLIMI_00082 543734.LCABL_14290 4.76e-217 599.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli,3FC3R@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system bcrA - - ko:K01990,ko:K19309 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC_tran AFLMLIMI_00083 543734.LCABL_14280 2.69e-156 439.0 COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,4IQ4T@91061|Bacilli,3F6RJ@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C AFLMLIMI_00084 543734.LCABL_14270 2.39e-200 556.0 COG0642@1|root,COG2205@2|Bacteria,1UZKD@1239|Firmicutes,4ITNE@91061|Bacilli,3FBXA@33958|Lactobacillaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c,HisKA AFLMLIMI_00085 543734.LCABL_14260 0.0 1075.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AFLMLIMI_00086 543734.LCABL_14250 8.16e-203 560.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HHQX@91061|Bacilli,3F6HU@33958|Lactobacillaceae 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisK - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - AFLMLIMI_00087 543734.LCABL_14240 2.05e-173 483.0 COG1428@1|root,COG1428@2|Bacteria,1TPJ1@1239|Firmicutes,4HA9N@91061|Bacilli,3F488@33958|Lactobacillaceae 91061|Bacilli F deoxynucleoside kinase - - - - - - - - - - - - dNK AFLMLIMI_00088 543734.LCABL_14230 2.93e-178 496.0 COG3201@1|root,COG3201@2|Bacteria,1VE5T@1239|Firmicutes,4HMNW@91061|Bacilli,3F3MB@33958|Lactobacillaceae 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter AFLMLIMI_00089 543734.LCABL_14220 3.35e-218 602.0 COG1028@1|root,COG1028@2|Bacteria,1VSDG@1239|Firmicutes,4HUM6@91061|Bacilli,3FB7Z@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short AFLMLIMI_00090 543734.LCABL_14210 6.93e-198 548.0 COG0225@1|root,COG0225@2|Bacteria,1TS05@1239|Firmicutes,4HAPI@91061|Bacilli,3FC52@33958|Lactobacillaceae 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine mrsA1 - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - EntA_Immun,PMSR AFLMLIMI_00091 543734.LCABL_14200 1.89e-157 442.0 COG0406@1|root,COG0406@2|Bacteria 2|Bacteria G alpha-ribazole phosphatase activity - - - - - - - - - - - - His_Phos_1 AFLMLIMI_00092 543734.LCABL_14190 4.62e-193 537.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli,3F3X8@33958|Lactobacillaceae 91061|Bacilli E L-serine dehydratase, iron-sulfur-dependent, alpha subunit sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha AFLMLIMI_00093 543734.LCABL_14180 1.02e-158 444.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli,3F4UB@33958|Lactobacillaceae 91061|Bacilli E Serine dehydratase beta chain sdaAB - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta AFLMLIMI_00094 543734.LCABL_14170 7e-142 400.0 COG4493@1|root,COG4493@2|Bacteria,1UY83@1239|Firmicutes,4HEDB@91061|Bacilli,3F62K@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0637 family yktB - - - - - - - - - - - DUF1054 AFLMLIMI_00095 543734.LCABL_14160 2.76e-99 288.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli,3F64D@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 AFLMLIMI_00096 543734.LCABL_14150 0.0 1253.0 COG1181@1|root,COG2918@1|root,COG1181@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli,3F506@33958|Lactobacillaceae 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshAB - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - Glu_cys_ligase AFLMLIMI_00097 543734.LCABL_14140 1.31e-303 828.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3WF@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N AFLMLIMI_00099 543734.LCABL_14130 1.93e-51 163.0 2BNXR@1|root,32HMR@2|Bacteria,1U7ZC@1239|Firmicutes,4IHWQ@91061|Bacilli,3FACP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00100 543734.LCABL_14120 2.86e-108 312.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,3F68T@33958|Lactobacillaceae 91061|Bacilli T universal stress protein uspA - - - - - - - - - - - Usp AFLMLIMI_00101 543734.LCABL_14110 2.7e-200 556.0 COG1476@1|root,COG1476@2|Bacteria,1VMYH@1239|Firmicutes,4ISF0@91061|Bacilli,3F5QH@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,TPR_8 AFLMLIMI_00102 543734.LCABL_14100 1.06e-149 421.0 COG0637@1|root,COG0637@2|Bacteria,1VA1U@1239|Firmicutes,4HMKX@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 3 yhfA - - - - - - - - - - - HAD_2 AFLMLIMI_00103 543734.LCABL_14090 3.03e-231 636.0 29SNM@1|root,30DU7@2|Bacteria,1V3Z9@1239|Firmicutes,4HHKX@91061|Bacilli,3F3VM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 AFLMLIMI_00104 543734.LCABL_14080 6.68e-75 224.0 COG5506@1|root,COG5506@2|Bacteria,1V8ID@1239|Firmicutes,4HJTQ@91061|Bacilli,3F7A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1694) - - - - - - - - - - - - DUF1694 AFLMLIMI_00105 1423732.BALS01000006_gene651 4.73e-31 109.0 29QHS@1|root,30BH8@2|Bacteria,1U84C@1239|Firmicutes,4II1T@91061|Bacilli,3FAIG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00106 543734.LCABL_14060 0.0 961.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli,3F44I@33958|Lactobacillaceae 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 AFLMLIMI_00107 543734.LCABL_14050 4.94e-103 298.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,3F6WP@33958|Lactobacillaceae 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N AFLMLIMI_00108 543734.LCABL_14040 1.3e-284 778.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli,3F3UP@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 AFLMLIMI_00109 543734.LCABL_14030 3.88e-243 668.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli,3F4BR@33958|Lactobacillaceae 91061|Bacilli O FeS assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 AFLMLIMI_00110 543734.LCABL_14020 4.15e-184 511.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,3F3XT@33958|Lactobacillaceae 91061|Bacilli O FeS assembly ATPase SufC sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran AFLMLIMI_00111 543734.LCABL_14010 1.31e-149 422.0 COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,4HBEV@91061|Bacilli,3F48A@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 AFLMLIMI_00112 543734.LCABL_14000 2.09e-243 669.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli,3F3U5@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL AFLMLIMI_00113 543734.LCABL_13990 8.04e-192 533.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 AFLMLIMI_00114 543734.LCABL_13980 1.88e-186 519.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 AFLMLIMI_00115 543734.LCABL_13970 3.19e-284 776.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AFLMLIMI_00116 543734.LCABL_13960 4.19e-65 198.0 COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,4HIMA@91061|Bacilli,3F7WB@33958|Lactobacillaceae 91061|Bacilli E glycine cleavage gcsH2 - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H AFLMLIMI_00117 543734.LCABL_13950 1.41e-285 780.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli,3F4J4@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE AFLMLIMI_00118 1423816.BACQ01000017_gene611 8.37e-42 137.0 2BQ47@1|root,30ACR@2|Bacteria,1U6GX@1239|Firmicutes,4IG94@91061|Bacilli,3F7W8@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 AFLMLIMI_00119 543734.LCABL_13930 1.14e-72 217.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli,3F7H1@33958|Lactobacillaceae 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic AFLMLIMI_00120 568703.LGG_01189 1.37e-26 97.8 2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4I4NP@91061|Bacilli,3F8Q0@33958|Lactobacillaceae 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA AFLMLIMI_00121 543734.LCABL_13910 4.12e-228 629.0 COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,4HA4S@91061|Bacilli,3F463@33958|Lactobacillaceae 91061|Bacilli D Cell shape determining protein MreB Mrl mbl - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl AFLMLIMI_00122 543734.LCABL_13900 8.38e-42 137.0 COG4836@1|root,COG4836@2|Bacteria,1U2FQ@1239|Firmicutes,4HNZX@91061|Bacilli,3F831@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1146) - - - - - - - - - - - - DUF1146 AFLMLIMI_00123 543734.LCABL_13890 1.88e-91 268.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli,3F6I6@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N AFLMLIMI_00124 543734.LCABL_13880 0.0 896.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli,3F3TF@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N AFLMLIMI_00125 543734.LCABL_13870 1.92e-211 585.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3F40E@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt AFLMLIMI_00126 543734.LCABL_13860 0.0 982.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli,3F3R4@33958|Lactobacillaceae 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N AFLMLIMI_00127 543734.LCABL_13850 2.77e-116 334.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,3F5TZ@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP AFLMLIMI_00128 543734.LCABL_13840 3.22e-83 249.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli,3F5M8@33958|Lactobacillaceae 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B AFLMLIMI_00129 543734.LCABL_13830 2.57e-37 125.0 COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,4HNKQ@91061|Bacilli,3F82A@33958|Lactobacillaceae 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C AFLMLIMI_00130 543734.LCABL_13820 1.23e-162 456.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli,3F3RE@33958|Lactobacillaceae 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A AFLMLIMI_00131 543734.LCABL_13810 3.05e-145 409.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli,3F4M0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase AFLMLIMI_00132 543734.LCABL_13800 1.83e-297 811.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,3F4C1@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT AFLMLIMI_00133 543734.LCABL_13790 4.89e-238 654.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,3F3T1@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC AFLMLIMI_00134 543734.LCABL_13780 1.34e-195 542.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS AFLMLIMI_00135 543734.LCABL_13770 4.99e-251 689.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli,3F3Q0@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 AFLMLIMI_00136 543734.LCABL_13760 7.61e-144 405.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,3F4UE@33958|Lactobacillaceae 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK AFLMLIMI_00137 543734.LCABL_13750 0.0 903.0 COG0770@1|root,COG0770@2|Bacteria,1TRG9@1239|Firmicutes,4HAMY@91061|Bacilli,3FBS5@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF1727) murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M AFLMLIMI_00138 543734.LCABL_13740 1.51e-250 687.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3FBDZ@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase ampC - - - - - - - - - - - Beta-lactamase AFLMLIMI_00139 543734.LCABL_13730 1.31e-208 576.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,3F62I@33958|Lactobacillaceae 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase AFLMLIMI_00140 543734.LCABL_13720 3.54e-179 499.0 COG0431@1|root,COG0431@2|Bacteria,1VBJA@1239|Firmicutes,4HSVK@91061|Bacilli,3F41J@33958|Lactobacillaceae 91061|Bacilli S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red AFLMLIMI_00141 543734.LCABL_13710 0.0 1206.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yfiC - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_00142 543734.LCABL_13700 0.0 1091.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ycfI - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_00143 543734.LCABL_13690 6.41e-155 434.0 COG1309@1|root,COG1309@2|Bacteria,1V6CF@1239|Firmicutes,4HJIC@91061|Bacilli,3FCEJ@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AFLMLIMI_00144 543734.LCABL_13680 6.07e-165 462.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HD4C@91061|Bacilli,3F50R@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family pgm7 - - - - - - - - - - - His_Phos_1 AFLMLIMI_00146 1400520.LFAB_00155 2.59e-151 439.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family sip - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase AFLMLIMI_00147 1449126.JQKL01000003_gene1715 6.11e-08 58.5 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24QK6@186801|Clostridia,26BN9@186813|unclassified Clostridiales 186801|Clostridia K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AFLMLIMI_00149 1291743.LOSG293_110590 9.39e-16 75.9 COG3646@1|root,COG3646@2|Bacteria,1UPF6@1239|Firmicutes 1239|Firmicutes S Phage regulatory protein - - - - - - - - - - - - ORF6C,ORF6N AFLMLIMI_00150 226185.EF_2037 1.17e-11 63.9 COG3646@1|root,COG3646@2|Bacteria,1TT7W@1239|Firmicutes,4HDGY@91061|Bacilli,4B1BD@81852|Enterococcaceae 91061|Bacilli S ORF6C domain - - - - - - - - - - - - ORF6C,Phage_pRha AFLMLIMI_00157 314315.LCA_0594 3.13e-93 283.0 COG5519@1|root,COG5519@2|Bacteria,1UJCM@1239|Firmicutes,4IT5B@91061|Bacilli,3FBUQ@33958|Lactobacillaceae 91061|Bacilli L Bifunctional DNA primase/polymerase, N-terminal - - - - - - - - - - - - PriCT_1,Prim-Pol AFLMLIMI_00158 999411.HMPREF1092_03334 1.93e-72 243.0 COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,36EHX@31979|Clostridiaceae 186801|Clostridia S virulence-associated E family protein - - - - - - - - - - - - VirE AFLMLIMI_00165 543734.LCABL_13640 0.0 986.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD2 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AFLMLIMI_00166 543734.LCABL_13630 4.36e-136 385.0 COG3548@1|root,COG3548@2|Bacteria,1U544@1239|Firmicutes,4IEVF@91061|Bacilli,3F4HQ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 AFLMLIMI_00167 543734.LCABL_13620 4.42e-271 743.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 AFLMLIMI_00168 1423732.BALS01000006_gene697 1.53e-19 79.7 29PYH@1|root,30AWY@2|Bacteria,1U77Q@1239|Firmicutes,4IH2I@91061|Bacilli,3F930@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00169 543734.LCABL_13600 2.11e-103 300.0 COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,4HK1B@91061|Bacilli,3F6ED@33958|Lactobacillaceae 91061|Bacilli T TspO/MBR family tspO - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR AFLMLIMI_00172 543734.LCABL_13570 5.68e-110 316.0 COG0590@1|root,COG0590@2|Bacteria,1V7G0@1239|Firmicutes,4HMR9@91061|Bacilli,3F6S6@33958|Lactobacillaceae 91061|Bacilli FJ MafB19-like deaminase guaD - - - - - - - - - - - MafB19-deam,dCMP_cyt_deam_1 AFLMLIMI_00173 543734.LCABL_13560 2.56e-219 605.0 COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,3F4BX@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold ysjB - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA AFLMLIMI_00174 543734.LCABL_13550 2.76e-294 801.0 COG0438@1|root,COG0438@2|Bacteria,1VIZB@1239|Firmicutes,4HU4N@91061|Bacilli,3F9Q1@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4 AFLMLIMI_00175 543734.LCABL_13530 4.8e-104 308.0 COG2433@1|root,COG2433@2|Bacteria,1VH0K@1239|Firmicutes,4ITND@91061|Bacilli,3FBX9@33958|Lactobacillaceae 91061|Bacilli S Pfam Transposase IS66 - - - - - - - - - - - - - AFLMLIMI_00176 543734.LCABL_13520 1.62e-195 543.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HHHQ@91061|Bacilli,3F4MB@33958|Lactobacillaceae 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 AFLMLIMI_00178 543734.LCABL_13500 2.12e-63 193.0 COG1359@1|root,COG1359@2|Bacteria,1VG4T@1239|Firmicutes,4HPNQ@91061|Bacilli,3F7H6@33958|Lactobacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase ycnE GO:0003674,GO:0003824 - - - - - - - - - - ABM AFLMLIMI_00179 543734.LCABL_13490 4.53e-64 201.0 28KYP@1|root,2ZAE6@2|Bacteria,1V775@1239|Firmicutes,4HMWB@91061|Bacilli,3F6AR@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function DUF1829 - - - - - - - - - - - - DUF1828,DUF1829 AFLMLIMI_00180 543734.LCABL_13490 3.1e-80 243.0 28KYP@1|root,2ZAE6@2|Bacteria,1V775@1239|Firmicutes,4HMWB@91061|Bacilli,3F6AR@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function DUF1829 - - - - - - - - - - - - DUF1828,DUF1829 AFLMLIMI_00182 1291743.LOSG293_110040 9.73e-30 117.0 COG3654@1|root,COG3654@2|Bacteria 2|Bacteria - - doc - - ko:K07341 - - - - ko00000,ko02048 - - - Fic,Virulence_RhuM AFLMLIMI_00183 543734.LCABL_13470 2.34e-266 731.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V16P@1239|Firmicutes,4HF99@91061|Bacilli,3FC13@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 AFLMLIMI_00184 543734.LCABL_13460 7.65e-82 243.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli,3F9QK@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin hol - - - - - - - - - - - Phage_holin_1 AFLMLIMI_00185 543734.LCABL_13450 4.52e-69 209.0 2EN82@1|root,33FVV@2|Bacteria,1VKRH@1239|Firmicutes,4HR3G@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00187 568703.LGG_01139 2.51e-191 575.0 COG4926@1|root,COG4926@2|Bacteria,1TTBV@1239|Firmicutes,4HBWT@91061|Bacilli 91061|Bacilli S cellulase activity - - - - - - - - - - - - Prophage_tail AFLMLIMI_00188 568703.LGG_01138 4.63e-185 546.0 COG4722@1|root,COG4722@2|Bacteria,1VB1N@1239|Firmicutes,4HPVS@91061|Bacilli 91061|Bacilli S Phage tail protein - - - - - - - - - - - - Sipho_tail AFLMLIMI_00189 568703.LGG_01137 0.0 1083.0 COG5412@1|root,COG5412@2|Bacteria,1W2PZ@1239|Firmicutes,4I175@91061|Bacilli,3F5MC@33958|Lactobacillaceae 91061|Bacilli S phage tail tape measure protein - - - - - - - - - - - - - AFLMLIMI_00190 568703.LGG_01136 1.57e-73 221.0 2EHS8@1|root,33BHZ@2|Bacteria,1VKIN@1239|Firmicutes,4HR6E@91061|Bacilli,3F7N3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00191 568703.LGG_01135 1.89e-64 197.0 2EBTF@1|root,333J2@2|Bacteria,1VHHD@1239|Firmicutes,4HQFJ@91061|Bacilli,3FBPF@33958|Lactobacillaceae 91061|Bacilli S Phage tail assembly chaperone protein, TAC - - - - - - - - - - - - Phage_TAC_12 AFLMLIMI_00192 543734.LCABL_13370 1.3e-132 377.0 2F0XZ@1|root,33TZM@2|Bacteria,1VUVY@1239|Firmicutes,4HVU9@91061|Bacilli,3F76N@33958|Lactobacillaceae 91061|Bacilli S Phage tail tube protein - - - - - - - - - - - - Phage_tail_2 AFLMLIMI_00193 543734.LCABL_13360 1.59e-90 265.0 2EIM8@1|root,33CCI@2|Bacteria,1VMSE@1239|Firmicutes,4HRDA@91061|Bacilli,3F7YS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 AFLMLIMI_00194 543734.LCABL_13350 8.92e-75 224.0 2CIV5@1|root,32ZS6@2|Bacteria,1VFPA@1239|Firmicutes,4HQWN@91061|Bacilli,3F8P3@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage HK97-gp10, putative tail-component - - - - - - - - - - - - HK97-gp10_like AFLMLIMI_00195 568703.LGG_01131 2.71e-66 201.0 2E86K@1|root,332JW@2|Bacteria,1VIHK@1239|Firmicutes,4HZJB@91061|Bacilli,3F8A2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00196 543734.LCABL_13330 2.53e-80 238.0 2EKJJ@1|root,33E9D@2|Bacteria,1VN9C@1239|Firmicutes,4HR20@91061|Bacilli,3F7K9@33958|Lactobacillaceae 91061|Bacilli S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 AFLMLIMI_00197 543734.LCABL_13300 4.93e-229 632.0 2DB75@1|root,2Z7JY@2|Bacteria,1TSI8@1239|Firmicutes,4IRVK@91061|Bacilli,3F5Z9@33958|Lactobacillaceae 91061|Bacilli S Phage major capsid protein E - - - - - - - - - - - - Phage_cap_E AFLMLIMI_00198 543734.LCABL_13280 4.97e-64 196.0 2EHA7@1|root,33B23@2|Bacteria,1VK8N@1239|Firmicutes,4HXXJ@91061|Bacilli,3F87M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00199 568703.LGG_01128 1.83e-108 317.0 2DNT1@1|root,32YZX@2|Bacteria,1VEET@1239|Firmicutes,4HQ00@91061|Bacilli,3F7QQ@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4355) - - - - - - - - - - - - DUF4355 AFLMLIMI_00202 445972.ANACOL_03351 2.85e-07 50.4 2CHCE@1|root,32Z7E@2|Bacteria,1VIXB@1239|Firmicutes,24TNE@186801|Clostridia,3WR43@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - - AFLMLIMI_00203 543734.LCABL_13260 5.25e-232 639.0 COG2369@1|root,COG2369@2|Bacteria,1U6KJ@1239|Firmicutes,4HGZW@91061|Bacilli,3F3Z8@33958|Lactobacillaceae 91061|Bacilli S head morphogenesis protein, SPP1 gp7 family - - - - - - - - - - - - Phage_Mu_F AFLMLIMI_00204 543734.LCABL_13250 0.0 892.0 2DB9U@1|root,2Z7Z6@2|Bacteria,1TR67@1239|Firmicutes,4HCTZ@91061|Bacilli,3FB8U@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_prot_Gp6 AFLMLIMI_00205 543734.LCABL_13240 1.68e-313 852.0 COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,4H9S2@91061|Bacilli,3F3NN@33958|Lactobacillaceae 91061|Bacilli S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C AFLMLIMI_00206 1423775.BAMN01000025_gene2809 1.36e-54 180.0 COG2963@1|root,COG2963@2|Bacteria,1V6XW@1239|Firmicutes,4HIUS@91061|Bacilli,3F7DT@33958|Lactobacillaceae 91061|Bacilli L transposase activity - - - - - - - - - - - - HTH_23 AFLMLIMI_00208 543734.LCABL_13210 4.86e-281 767.0 2C1BV@1|root,32ZTD@2|Bacteria,1VGE5@1239|Firmicutes,4HPF9@91061|Bacilli,3F9J1@33958|Lactobacillaceae 91061|Bacilli S GcrA cell cycle regulator - - - - - - - - - - - - GcrA AFLMLIMI_00212 543734.LCABL_05720 7.79e-69 211.0 2DCNS@1|root,2ZESF@2|Bacteria,1W51N@1239|Firmicutes,4I1NU@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00218 1423816.BACQ01000027_gene954 8.42e-42 141.0 29Q9M@1|root,30B8Q@2|Bacteria,1U7QY@1239|Firmicutes,4IHN8@91061|Bacilli,3FA1A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00221 1423732.BALS01000058_gene2831 3.06e-55 178.0 29Q9Z@1|root,30B93@2|Bacteria,1U7RI@1239|Firmicutes,4IHNV@91061|Bacilli,3FA2I@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 AFLMLIMI_00224 543734.LCABL_22720 2.41e-116 344.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HDHJ@91061|Bacilli,3FC9T@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase AFLMLIMI_00225 146269.A8YQM7_9CAUD 3.8e-159 447.0 4QC87@10239|Viruses,4QUN8@35237|dsDNA viruses no RNA stage,4QRGW@28883|Caudovirales,4QMER@10699|Siphoviridae 10699|Siphoviridae S DNA methylation - - - - - - - - - - - - - AFLMLIMI_00226 279281.Q6J1V2_9CAUD 5.89e-76 228.0 4QZQH@35237|dsDNA viruses no RNA stage,4QQW9@28883|Caudovirales,4QN19@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1064) - - - - - - - - - - - - - AFLMLIMI_00227 1423732.BALS01000098_gene1435 1.44e-59 188.0 29Q0P@1|root,30AZ5@2|Bacteria,1U7AM@1239|Firmicutes,4IH5K@91061|Bacilli,3F97Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00229 1423816.BACQ01000027_gene964 9.47e-158 444.0 COG1484@1|root,COG1484@2|Bacteria,1V36Z@1239|Firmicutes,4HXKM@91061|Bacilli,3F6VF@33958|Lactobacillaceae 91061|Bacilli L IstB-like ATP binding protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 AFLMLIMI_00230 543734.LCABL_13070 1.59e-158 451.0 COG3935@1|root,COG3935@2|Bacteria,1VHH7@1239|Firmicutes,4HK51@91061|Bacilli,3F8M1@33958|Lactobacillaceae 91061|Bacilli L Replication initiation and membrane attachment - - - - - - - - - - - - DnaB_2,HTH_36 AFLMLIMI_00231 543734.LCABL_13060 2.08e-187 521.0 COG1074@1|root,COG1074@2|Bacteria,1V1UQ@1239|Firmicutes,4HGSG@91061|Bacilli,3F51S@33958|Lactobacillaceae 91061|Bacilli L PDDEXK-like domain of unknown function (DUF3799) pi112 - - - - - - - - - - - DUF3799 AFLMLIMI_00232 543734.LCABL_13050 5.91e-200 554.0 COG3723@1|root,COG3723@2|Bacteria,1UNDF@1239|Firmicutes,4HB2T@91061|Bacilli,3F6D8@33958|Lactobacillaceae 91061|Bacilli L RecT family recT - - ko:K07455 - - - - ko00000,ko03400 - - - RecT AFLMLIMI_00235 543734.LCABL_13030 7.24e-23 87.4 29QME@1|root,30BM2@2|Bacteria,1U8B1@1239|Firmicutes,4II91@91061|Bacilli,3FASG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00237 543734.LCABL_13020 7.71e-128 363.0 2ERS9@1|root,32C80@2|Bacteria,1U7E6@1239|Firmicutes,4IHA2@91061|Bacilli,3F9GF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00241 279010.BL05118 1.01e-14 70.1 COG1813@1|root,COG1813@2|Bacteria,1UAQB@1239|Firmicutes,4IM30@91061|Bacilli,1ZIYU@1386|Bacillus 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 AFLMLIMI_00242 1591072.A0A0B5CYL9_9CAUD 7.07e-32 117.0 4QAQV@10239|Viruses,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010944,GO:0016032,GO:0019012,GO:0019042,GO:0019044,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043900,GO:0043902,GO:0043903,GO:0044212,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0046782,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0050434,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - AFLMLIMI_00244 1423807.BACO01000025_gene815 1.12e-72 225.0 2DPC1@1|root,331GC@2|Bacteria,1VE35@1239|Firmicutes,4HMP3@91061|Bacilli,3F66X@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4352) - - - - - - - - - - - - DUF4352 AFLMLIMI_00245 543734.LCABL_12920 1.1e-89 263.0 COG3871@1|root,COG3871@2|Bacteria,1V1KZ@1239|Firmicutes,4I1P9@91061|Bacilli,3F7W7@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx AFLMLIMI_00246 568703.LGG_01089 5.3e-40 132.0 2AI1X@1|root,318FN@2|Bacteria,1U7VR@1239|Firmicutes,4IHT4@91061|Bacilli,3FA8F@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00247 568703.LGG_01088 3.96e-228 629.0 2E3RY@1|root,32YPJ@2|Bacteria,1VIPM@1239|Firmicutes,4HPWV@91061|Bacilli,3F8AU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00249 543734.LCABL_12880 7.89e-268 735.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HEI7@91061|Bacilli,3F5DJ@33958|Lactobacillaceae 91061|Bacilli L Pfam:Integrase_AP2 - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase AFLMLIMI_00250 543734.LCABL_12870 0.0 889.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli,3F3XK@33958|Lactobacillaceae 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI AFLMLIMI_00251 543734.LCABL_12860 6.61e-196 544.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli,3F4K2@33958|Lactobacillaceae 91061|Bacilli U sugar transport glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport AFLMLIMI_00252 543734.LCABL_12840 1.59e-143 404.0 COG4767@1|root,COG4767@2|Bacteria,1VK3A@1239|Firmicutes,4HPCD@91061|Bacilli,3F5EN@33958|Lactobacillaceae 91061|Bacilli V VanZ like family vanZ - - - - - - - - - - - VanZ AFLMLIMI_00253 543734.LCABL_12830 0.0 1463.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase AFLMLIMI_00254 1423732.BALS01000024_gene2404 4.26e-137 392.0 29Z4F@1|root,30M23@2|Bacteria,1U7B2@1239|Firmicutes,4IH62@91061|Bacilli,3F98Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00255 543734.LCABL_12810 7.65e-136 384.0 29PYD@1|root,30AWT@2|Bacteria,1U77H@1239|Firmicutes,4IH2B@91061|Bacilli,3F92N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00256 543734.LCABL_12800 2.81e-314 855.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli,3F48P@33958|Lactobacillaceae 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 AFLMLIMI_00257 543734.LCABL_12790 6.67e-261 715.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK2 - 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp AFLMLIMI_00258 543734.LCABL_12780 6.23e-303 828.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli,3F3Y7@33958|Lactobacillaceae 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease AFLMLIMI_00259 543734.LCABL_12770 5.35e-133 377.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli,3F49S@33958|Lactobacillaceae 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran AFLMLIMI_00260 543734.LCABL_12760 1.45e-149 421.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli,3F584@33958|Lactobacillaceae 91061|Bacilli NU mannosyl-glycoprotein acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG AFLMLIMI_00261 543734.LCABL_12750 3.95e-108 311.0 COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,4HH45@91061|Bacilli,3F7GI@33958|Lactobacillaceae 91061|Bacilli K GNAT family yvbK - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 AFLMLIMI_00262 1423732.BALS01000024_gene2412 6.22e-43 139.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae 91061|Bacilli K Cold shock protein cspC - - ko:K03704 - - - - ko00000,ko03000 - - - CSD AFLMLIMI_00264 543734.LCABL_12730 8.49e-217 600.0 COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,4HAWV@91061|Bacilli,3F54Y@33958|Lactobacillaceae 91061|Bacilli S Putative aromatic acid exporter C-terminal domain yqjA - - - - - - - - - - - ArAE_1,ArAE_1_C AFLMLIMI_00265 543734.LCABL_12720 4.24e-133 379.0 28T4I@1|root,2ZFDJ@2|Bacteria,1W6RG@1239|Firmicutes,4HZG4@91061|Bacilli,3F88M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - YkyA AFLMLIMI_00266 543734.LCABL_12710 1.42e-218 603.0 COG1216@1|root,COG1216@2|Bacteria,1UHWE@1239|Firmicutes,4ISA4@91061|Bacilli,3F3JX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 2 family protein yfdH - - ko:K12999 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 AFLMLIMI_00267 543734.LCABL_12700 0.0 1109.0 COG5617@1|root,COG5617@2|Bacteria,1VS0Z@1239|Firmicutes,4HJQE@91061|Bacilli,3FBX8@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - PTPS_related AFLMLIMI_00268 543734.LCABL_12690 0.0 1697.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli,3FC7P@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO AFLMLIMI_00269 543734.LCABL_12680 1.23e-191 532.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HEI6@91061|Bacilli,3F6PD@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain licT2 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD AFLMLIMI_00270 543734.LCABL_12670 0.0 1104.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system bglH - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AFLMLIMI_00271 543734.LCABL_12660 0.0 976.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AFLMLIMI_00272 543734.LCABL_12650 0.0 1005.0 COG5492@1|root,COG5492@2|Bacteria,1U5Y9@1239|Firmicutes,4IFME@91061|Bacilli,3F6PJ@33958|Lactobacillaceae 91061|Bacilli N domain, Protein - - - - - - - - - - - - - AFLMLIMI_00274 543734.LCABL_12630 4.02e-169 479.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 AFLMLIMI_00276 568703.LGG_00482 1.41e-69 221.0 29Q5Q@1|root,30B4M@2|Bacteria,1U7IV@1239|Firmicutes,4IHFN@91061|Bacilli,3F9S6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00277 1423816.BACQ01000020_gene672 2.99e-52 213.0 COG5295@1|root,COG5295@2|Bacteria,1VIS5@1239|Firmicutes,4HIVX@91061|Bacilli,3F567@33958|Lactobacillaceae 91061|Bacilli UW Tetratricopeptide repeat - - - - - - - - - - - - Gram_pos_anchor AFLMLIMI_00278 1423816.BACQ01000020_gene672 8.18e-51 200.0 COG5295@1|root,COG5295@2|Bacteria,1VIS5@1239|Firmicutes,4HIVX@91061|Bacilli,3F567@33958|Lactobacillaceae 91061|Bacilli UW Tetratricopeptide repeat - - - - - - - - - - - - Gram_pos_anchor AFLMLIMI_00280 1221537.B807_584 3.26e-88 271.0 2F0KB@1|root,33TNZ@2|Bacteria,1VRXR@1239|Firmicutes,4HT3X@91061|Bacilli,3F6NR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00281 1423807.BACO01000060_gene1740 1.28e-222 628.0 COG0438@1|root,COG0438@2|Bacteria,1V31K@1239|Firmicutes,4IPIN@91061|Bacilli,3FBF2@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 AFLMLIMI_00282 1408438.JADD01000009_gene1841 1.9e-08 60.1 2AFSZ@1|root,315V3@2|Bacteria,1V6D1@1239|Firmicutes,4HS4W@91061|Bacilli 91061|Bacilli S Accessory Sec system protein Asp3 asp3 - - ko:K12270 - - - - ko00000,ko02044 3.A.5.10 - - Sec-ASP3 AFLMLIMI_00283 1221537.B807_587 6.77e-140 421.0 COG1073@1|root,COG1073@2|Bacteria,1TSWW@1239|Firmicutes,4HB1I@91061|Bacilli,3F5ZE@33958|Lactobacillaceae 91061|Bacilli S Accessory Sec system GspB-transporter asp2 - - ko:K12269 - - - - ko00000,ko02044 3.A.5.10 - - Asp2 AFLMLIMI_00284 1423816.BACQ01000020_gene678 2.38e-42 166.0 2CI7G@1|root,2ZBRM@2|Bacteria,1V1BC@1239|Firmicutes,4HKRQ@91061|Bacilli,3F6N6@33958|Lactobacillaceae 91061|Bacilli S Accessory Sec system protein Asp1 asp1 - - ko:K12268 - - - - ko00000,ko02044 3.A.5.10 - - Asp1 AFLMLIMI_00285 1423807.BACO01000060_gene1736 2.9e-85 273.0 COG0201@1|root,COG0201@2|Bacteria,1V59T@1239|Firmicutes,4HH1U@91061|Bacilli,3F6CD@33958|Lactobacillaceae 91061|Bacilli U SecY translocase secY2 - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY AFLMLIMI_00286 1221537.B807_590 1.64e-310 875.0 COG0653@1|root,COG0653@2|Bacteria,1TRJA@1239|Firmicutes,4HCH0@91061|Bacilli,3F50U@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA2 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SecA_DEAD,SecA_PP_bind,SecA_SW AFLMLIMI_00287 1423755.BAML01000011_gene916 6.46e-43 158.0 COG0438@1|root,COG0438@2|Bacteria,1V8J0@1239|Firmicutes,4HVPH@91061|Bacilli,3FBD0@33958|Lactobacillaceae 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - AFLMLIMI_00288 1423775.BAMN01000037_gene1636 4.33e-09 63.9 COG1442@1|root,COG1442@2|Bacteria,1UY8Y@1239|Firmicutes,4HBAE@91061|Bacilli,3F4YJ@33958|Lactobacillaceae 91061|Bacilli M family 8 gspA - - - - - - - - - - - Glyco_transf_8 AFLMLIMI_00290 543734.LCABL_12560 6.51e-217 598.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,3F45A@33958|Lactobacillaceae 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase AFLMLIMI_00291 543734.LCABL_12550 1.09e-253 696.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HC93@91061|Bacilli,3F3RZ@33958|Lactobacillaceae 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N AFLMLIMI_00292 1423732.BALS01000059_gene2808 1.22e-141 407.0 COG1442@1|root,COG1442@2|Bacteria 2|Bacteria M lipopolysaccharide 3-alpha-galactosyltransferase activity - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0016740,GO:0016757,GO:0043170,GO:0044238,GO:0071704,GO:1901576 - - - - - - - - - - GT-D,Glyco_transf_8 AFLMLIMI_00293 568703.LGG_01060 1.02e-20 84.0 2BQ1G@1|root,32IVS@2|Bacteria,1U82T@1239|Firmicutes,4II07@91061|Bacilli,3FAGJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00295 543734.LCABL_12520 1.24e-257 706.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 AFLMLIMI_00296 543734.LCABL_12510 1.16e-204 565.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,3F3MK@33958|Lactobacillaceae 91061|Bacilli E Methionine Aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 AFLMLIMI_00297 543734.LCABL_12500 1.24e-103 300.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli,3F6HY@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin fld - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 AFLMLIMI_00298 543734.LCABL_12490 9.73e-230 634.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,3F4TC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB AFLMLIMI_00299 543734.LCABL_12480 0.0 898.0 COG4320@1|root,COG4320@2|Bacteria,1UCBA@1239|Firmicutes,4HBCI@91061|Bacilli,3F3JA@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2252) - - - ko:K13730 ko05100,map05100 - - - ko00000,ko00001 - - - DUF2252 AFLMLIMI_00300 543734.LCABL_12470 2.96e-144 406.0 COG1309@1|root,COG1309@2|Bacteria,1V8EE@1239|Firmicutes,4HJF2@91061|Bacilli,3FBGB@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N,WHG AFLMLIMI_00301 543734.LCABL_12460 1.47e-166 472.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,3F53R@33958|Lactobacillaceae 91061|Bacilli E Thermophilic metalloprotease (M29) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 AFLMLIMI_00302 543734.LCABL_12460 6.3e-114 336.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,3F53R@33958|Lactobacillaceae 91061|Bacilli E Thermophilic metalloprotease (M29) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 AFLMLIMI_00303 543734.LCABL_12450 0.0 1164.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind AFLMLIMI_00304 1291743.LOSG293_160010 7.67e-07 57.0 arCOG05209@1|root,31PIN@2|Bacteria,1V5G2@1239|Firmicutes,4HIRV@91061|Bacilli,3F6X9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00306 543734.LCABL_12420 4.49e-93 272.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F875@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 AFLMLIMI_00307 543734.LCABL_12410 7.9e-74 222.0 COG1447@1|root,COG1447@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system chbA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0016043,GO:0016740,GO:0016772,GO:0016773,GO:0022607,GO:0022804,GO:0022857,GO:0034219,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0071702,GO:0071840,GO:0090563,GO:0090566,GO:1901264,GO:1902815 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - iECABU_c1320.ECABU_c17610,iECOK1_1307.ECOK1_1683,iECUMN_1333.ECUMN_2025,iNRG857_1313.NRG857_07575,iUMN146_1321.UM146_09345 PTS_IIA AFLMLIMI_00308 543734.LCABL_12400 4.41e-289 791.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli,3F4K8@33958|Lactobacillaceae 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C AFLMLIMI_00309 543734.LCABL_12390 2.21e-226 624.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,3F4EV@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase mocA - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C AFLMLIMI_00310 543734.LCABL_12380 1.9e-79 236.0 2EGZM@1|root,33ARR@2|Bacteria,1VNS7@1239|Firmicutes,4HSZW@91061|Bacilli,3F83W@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4828) - - - - - - - - - - - - DUF4828 AFLMLIMI_00311 543734.LCABL_12370 9.39e-80 236.0 COG5294@1|root,COG5294@2|Bacteria,1VF0I@1239|Firmicutes,4HPC2@91061|Bacilli,3F83V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 AFLMLIMI_00312 543734.LCABL_12360 1.02e-179 499.0 COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,4HJNJ@91061|Bacilli,3FC1I@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - ko:K07273 - - - - ko00000 - - - Glyco_hydro_25,PG_binding_1 AFLMLIMI_00313 543734.LCABL_12350 1.24e-39 131.0 29PRV@1|root,30AQ2@2|Bacteria,1U6Z0@1239|Firmicutes,4IGT9@91061|Bacilli,3F8R4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00314 543734.LCABL_12340 5.58e-165 468.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli,3F4HV@33958|Lactobacillaceae 91061|Bacilli O prohibitin homologues hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 AFLMLIMI_00315 543734.LCABL_12330 2.87e-213 588.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,3F4II@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein, DegV family COG1307 yitS - - - - - - - - - - - DegV AFLMLIMI_00316 543734.LCABL_12320 5.98e-105 303.0 COG0454@1|root,COG0456@2|Bacteria,1VBAA@1239|Firmicutes,4HN0D@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 AFLMLIMI_00317 543734.LCABL_12310 2.07e-273 751.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_3,Sugar_tr AFLMLIMI_00318 543734.LCABL_12310 7.06e-29 114.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_3,Sugar_tr AFLMLIMI_00319 543734.LCABL_12300 0.0 1271.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F9J0@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N AFLMLIMI_00320 543734.LCABL_12290 8.52e-211 582.0 COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,4HDT2@91061|Bacilli,3F59Q@33958|Lactobacillaceae 91061|Bacilli S Polyphosphate nucleotide phosphotransferase, PPK2 family - - - - - - - - - - - - PPK2 AFLMLIMI_00321 543734.LCABL_12280 8.81e-191 530.0 COG0561@1|root,COG0561@2|Bacteria,1VAFW@1239|Firmicutes,4HWQV@91061|Bacilli,3FC8C@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 AFLMLIMI_00322 543734.LCABL_12270 3.76e-280 767.0 COG0477@1|root,COG2814@2|Bacteria,1TPJ6@1239|Firmicutes,4HAGJ@91061|Bacilli,3F4F9@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator yttB - - - - - - - - - - - MFS_1 AFLMLIMI_00323 543734.LCABL_12260 0.0 888.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F41R@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_2 - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr AFLMLIMI_00324 543734.LCABL_12250 4.97e-248 681.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,3F447@33958|Lactobacillaceae 91061|Bacilli G Lipid kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat AFLMLIMI_00325 543734.LCABL_12240 0.0 958.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli,3F44H@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey AFLMLIMI_00326 543734.LCABL_12220 3.61e-61 188.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,3F7XB@33958|Lactobacillaceae 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln AFLMLIMI_00327 543734.LCABL_12210 1.22e-270 741.0 COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,4HBI8@91061|Bacilli,3F3KI@33958|Lactobacillaceae 91061|Bacilli S sex pheromone camS - - - - - - - - - - - CamS AFLMLIMI_00328 543734.LCABL_12200 0.0 1316.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,3F43C@33958|Lactobacillaceae 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 AFLMLIMI_00329 543734.LCABL_12190 0.0 1466.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C AFLMLIMI_00331 543734.LCABL_12180 5.65e-46 150.0 COG4269@1|root,COG4269@2|Bacteria,1VA3P@1239|Firmicutes,4HK0T@91061|Bacilli,3F733@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF898) - - - - - - - - - - - - DUF898 AFLMLIMI_00332 543734.LCABL_12170 1.74e-180 503.0 COG2755@1|root,COG2755@2|Bacteria,1VIWQ@1239|Firmicutes,4HPR5@91061|Bacilli,3F8I7@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL,Lipase_GDSL_2 AFLMLIMI_00333 543734.LCABL_12160 1.78e-266 732.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 AFLMLIMI_00335 543734.LCABL_12140 0.0 873.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli,3F3WN@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA polymerase type-Y family polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH AFLMLIMI_00336 543734.LCABL_12130 8.56e-74 221.0 28WF1@1|root,2ZIF8@2|Bacteria,1W2PF@1239|Firmicutes,4HZUK@91061|Bacilli,3F8BE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00337 1423816.BACQ01000022_gene734 1.53e-88 263.0 29Q3G@1|root,30B24@2|Bacteria,1U7EM@1239|Firmicutes,4IHAG@91061|Bacilli,3F9HE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00338 543734.LCABL_12100 7.36e-94 274.0 COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,4HFRC@91061|Bacilli,3F6TJ@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0735 family pheB - 5.4.99.5 ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024,M00025 R01715 RC03116 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27910 ACT,ACT_4 AFLMLIMI_00339 568703.LGG_01006 5.2e-20 82.0 29QKN@1|root,30BKA@2|Bacteria,1U89K@1239|Firmicutes,4II7H@91061|Bacilli,3FAQS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00340 1423816.BACQ01000022_gene737 1.63e-97 286.0 COG3153@1|root,COG3153@2|Bacteria,1W0Z5@1239|Firmicutes,4HZAD@91061|Bacilli,3FBB4@33958|Lactobacillaceae 91061|Bacilli S acetyltransferase - - - - - - - - - - - - Acetyltransf_1 AFLMLIMI_00341 543734.LCABL_12060 0.0 940.0 COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4H9UD@91061|Bacilli,3F3Z4@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase yclK - - - - - - - - - - - HAMP,HATPase_c,HisKA AFLMLIMI_00342 543734.LCABL_12050 1.02e-173 484.0 COG0745@1|root,COG0745@2|Bacteria,1TQUQ@1239|Firmicutes,4HAXP@91061|Bacilli,3F3QZ@33958|Lactobacillaceae 91061|Bacilli K response regulator yclJ - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C AFLMLIMI_00343 543734.LCABL_12040 6.55e-93 271.0 COG5658@1|root,2ZY3R@2|Bacteria,1VKM4@1239|Firmicutes,4I0CM@91061|Bacilli,3F6IB@33958|Lactobacillaceae 91061|Bacilli S SdpI/YhfL protein family - - - - - - - - - - - - SdpI AFLMLIMI_00346 543734.LCABL_12010 0.0 1552.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase rafA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase AFLMLIMI_00347 543734.LCABL_12000 2.18e-212 586.0 COG0204@1|root,COG0204@2|Bacteria,1V2F4@1239|Firmicutes,4IF2T@91061|Bacilli,3F5FU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbZ - - - - - - - - - - - Acyltransferase AFLMLIMI_00348 543734.LCABL_11990 4.48e-231 635.0 COG1442@1|root,COG1442@2|Bacteria,1UY8Y@1239|Firmicutes,4HBAE@91061|Bacilli,3F4YJ@33958|Lactobacillaceae 91061|Bacilli M family 8 arbY - - - - - - - - - - - Glyco_transf_8 AFLMLIMI_00349 543734.LCABL_11980 2.02e-212 585.0 COG1442@1|root,COG1442@2|Bacteria,1UY4M@1239|Firmicutes,4IEY6@91061|Bacilli,3F4YZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 8 arbx - - - - - - - - - - - Glyco_transf_8 AFLMLIMI_00350 543734.LCABL_11970 7.51e-191 528.0 COG0204@1|root,COG0204@2|Bacteria,1V6NX@1239|Firmicutes,4IQ5I@91061|Bacilli,3FBFU@33958|Lactobacillaceae 91061|Bacilli I Phosphate acyltransferases arbV - - - - - - - - - - - Acyltransferase AFLMLIMI_00351 543734.LCABL_11960 0.0 888.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease AFLMLIMI_00352 543734.LCABL_11950 2.1e-81 243.0 2BH80@1|root,32B99@2|Bacteria,1U70M@1239|Firmicutes,4IGUY@91061|Bacilli,3F8TH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00353 543734.LCABL_11940 1.25e-237 654.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli,3F4CI@33958|Lactobacillaceae 91061|Bacilli L N-6 DNA Methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase AFLMLIMI_00355 568703.LGG_00992 1.42e-24 99.8 29Q7R@1|root,30B6S@2|Bacteria,1U7MZ@1239|Firmicutes,4IHJ8@91061|Bacilli,3F9XI@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - - AFLMLIMI_00356 568703.LGG_00991 8.98e-30 109.0 2AHWS@1|root,3189N@2|Bacteria,1U7TM@1239|Firmicutes,4IHR3@91061|Bacilli,3FA5S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00358 1423732.BALS01000047_gene2628 1e-35 124.0 2BKDX@1|root,32EUM@2|Bacteria,1U7Q0@1239|Firmicutes,4IHMB@91061|Bacilli,3FA01@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - - AFLMLIMI_00359 543734.LCABL_11880 7.91e-219 604.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli,3F3S9@33958|Lactobacillaceae 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF AFLMLIMI_00360 543734.LCABL_11870 1.16e-194 541.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3F4HY@33958|Lactobacillaceae 91061|Bacilli NU Type II IV secretion system protein comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE AFLMLIMI_00361 543734.LCABL_11860 5.85e-169 472.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli,3F4WF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg AFLMLIMI_00362 543734.LCABL_11850 1.94e-105 305.0 COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,4HMDE@91061|Bacilli,3F57S@33958|Lactobacillaceae 91061|Bacilli S VanZ like family - - - - - - - - - - - - VanZ AFLMLIMI_00363 543734.LCABL_11840 0.0 1202.0 COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,3F4ZV@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF2 - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N AFLMLIMI_00365 543734.LCABL_11830 0.0 1160.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli,3F467@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS AFLMLIMI_00366 543734.LCABL_11820 0.0 885.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,3F3W5@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV AFLMLIMI_00367 543734.LCABL_11810 5.49e-215 598.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,3F41C@33958|Lactobacillaceae 91061|Bacilli S YbbR-like protein ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR AFLMLIMI_00368 543734.LCABL_11800 3.82e-195 542.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli,3F4N3@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N AFLMLIMI_00369 543734.LCABL_11790 4.45e-169 473.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli,3F3VV@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00370 543734.LCABL_11780 2.3e-241 667.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,3F40D@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 AFLMLIMI_00371 543734.LCABL_11770 1.5e-143 405.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,3F6RQ@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N AFLMLIMI_00372 543734.LCABL_11760 0.0 1785.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli,3FC0Z@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 AFLMLIMI_00374 543734.LCABL_11740 8.49e-267 729.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli,3F3W1@33958|Lactobacillaceae 91061|Bacilli P ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 AFLMLIMI_00375 543734.LCABL_11730 2.88e-187 521.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli,3F3ZN@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 AFLMLIMI_00376 543734.LCABL_11720 1.44e-189 527.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli,3F4CM@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 AFLMLIMI_00377 543734.LCABL_11710 9.1e-263 719.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,3F40H@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 AFLMLIMI_00378 543734.LCABL_11700 1.97e-124 354.0 COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,4HHAY@91061|Bacilli,3FCDZ@33958|Lactobacillaceae 91061|Bacilli K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3 AFLMLIMI_00379 543734.LCABL_11690 0.0 1312.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter yvgP GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger AFLMLIMI_00380 543734.LCABL_11680 4.74e-213 588.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,3F40T@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation murB GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C AFLMLIMI_00381 543734.LCABL_11670 8.14e-194 536.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli,3F4GK@33958|Lactobacillaceae 91061|Bacilli L exodeoxyribonuclease III exoA GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos AFLMLIMI_00382 543734.LCABL_11660 8.04e-129 365.0 COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,4HI1V@91061|Bacilli,3F42Z@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T AFLMLIMI_00383 543734.LCABL_11650 2.34e-271 746.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein ysdA - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 AFLMLIMI_00384 543734.LCABL_11640 1.6e-214 592.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli,3F4J8@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ysdB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 AFLMLIMI_00386 543734.LCABL_11630 3.18e-106 306.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae 91061|Bacilli O Hydrolase, P-loop family ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE AFLMLIMI_00387 543734.LCABL_11620 1.01e-226 625.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli,3F3MW@33958|Lactobacillaceae 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB AFLMLIMI_00388 543734.LCABL_11610 1.45e-166 465.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,3F3W0@33958|Lactobacillaceae 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG AFLMLIMI_00389 543734.LCABL_11600 1.63e-202 561.0 COG0561@1|root,COG0561@2|Bacteria,1V5FB@1239|Firmicutes,4HGY8@91061|Bacilli,3F58Y@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase ycsE - - - - - - - - - - - Hydrolase_3 AFLMLIMI_00390 543734.LCABL_11590 7.57e-119 339.0 COG4894@1|root,COG4894@2|Bacteria,1V8EY@1239|Firmicutes,4HMMS@91061|Bacilli,3F698@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - LOR AFLMLIMI_00391 543734.LCABL_11580 3.63e-136 385.0 COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HJ11@91061|Bacilli,3FB97@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K06977 - - - - ko00000 - - - Acetyltransf_1 AFLMLIMI_00392 543734.LCABL_11570 3.08e-248 682.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HBKK@91061|Bacilli,3FC3J@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities malK - - ko:K10112,ko:K17240 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00599,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.38 - - ABC_tran,TOBE_2 AFLMLIMI_00393 543734.LCABL_11560 7.01e-213 588.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 AFLMLIMI_00394 543734.LCABL_11550 1.1e-188 525.0 COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,3FC8I@33958|Lactobacillaceae 91061|Bacilli G Binding-protein-dependent transport system inner membrane component malF - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 AFLMLIMI_00395 543734.LCABL_11540 8.67e-312 850.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HEKH@91061|Bacilli,3F4P5@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 AFLMLIMI_00396 543734.LCABL_11530 8.83e-307 835.0 COG0595@1|root,COG0595@2|Bacteria,1V0AV@1239|Firmicutes,4HEB0@91061|Bacilli,3FB9R@33958|Lactobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily YSH1 - - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,Lactamase_B_2 AFLMLIMI_00397 543734.LCABL_11520 1.13e-32 113.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3F85E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 AFLMLIMI_00399 543734.LCABL_11500 6.34e-194 539.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli,3F4NP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 AFLMLIMI_00400 543734.LCABL_11490 1.89e-309 845.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli,3F4J1@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component malF - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 AFLMLIMI_00401 543734.LCABL_11480 6.27e-289 790.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4HBHE@91061|Bacilli,3FC77@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein mdxE - - ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 M00207,M00491,M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.38 - iYO844.BSU34610 SBP_bac_8 AFLMLIMI_00402 543734.LCABL_11470 0.0 1112.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein dexB - 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C AFLMLIMI_00403 543734.LCABL_11460 3.2e-268 734.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,3FC3D@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 AFLMLIMI_00404 543734.LCABL_11450 3.78e-134 382.0 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HHB1@91061|Bacilli,3FCA1@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 AFLMLIMI_00405 543734.LCABL_11450 1.09e-09 57.4 COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HHB1@91061|Bacilli,3FCA1@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - 5.4.2.6 ko:K01838 ko00500,map00500 - R02728,R11310 RC00408 ko00000,ko00001,ko01000 - - - HAD_2 AFLMLIMI_00406 543734.LCABL_11440 0.0 1516.0 COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,3F3PG@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 65, central catalytic mapA - 2.4.1.8 ko:K00691 ko00500,ko01100,map00500,map01100 - R01555 RC00049 ko00000,ko00001,ko01000 - GH65 - Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m AFLMLIMI_00407 543734.LCABL_11430 0.0 1211.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family nplT - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Alpha-amylase_N,Malt_amylase_C AFLMLIMI_00408 543734.LCABL_11420 0.0 1117.0 COG0366@1|root,COG0366@2|Bacteria,1UY2T@1239|Firmicutes,4HBRE@91061|Bacilli,3FC10@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain malA1 - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C AFLMLIMI_00409 543734.LCABL_11410 1.09e-226 624.0 COG1609@1|root,COG1609@2|Bacteria,1U6Z4@1239|Firmicutes,4HC2A@91061|Bacilli,3F3ZC@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor yvdE - - - - - - - - - - - LacI,Peripla_BP_3 AFLMLIMI_00410 543734.LCABL_11400 4.47e-108 311.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,3F65B@33958|Lactobacillaceae 91061|Bacilli J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB AFLMLIMI_00411 543734.LCABL_11390 0.0 1573.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 AFLMLIMI_00412 543734.LCABL_11380 4.01e-181 503.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4HBE6@91061|Bacilli,3F5XW@33958|Lactobacillaceae 91061|Bacilli S Serine aminopeptidase, S33 est GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 AFLMLIMI_00413 543734.LCABL_11370 5.04e-43 140.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli,3F7IQ@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG AFLMLIMI_00414 543734.LCABL_11360 0.0 1007.0 COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli,3F3MU@33958|Lactobacillaceae 91061|Bacilli P chloride eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC AFLMLIMI_00415 543734.LCABL_11350 1.33e-63 195.0 29QBC@1|root,30BAJ@2|Bacteria,1U7TN@1239|Firmicutes,4IHR4@91061|Bacilli,3FA5U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00416 543734.LCABL_11340 5.21e-293 801.0 COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HBXV@91061|Bacilli,3F5A0@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector mdt(A) - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1,MFS_2,MFS_3 AFLMLIMI_00417 543734.LCABL_11330 3.4e-312 850.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,3F3JP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N AFLMLIMI_00418 543734.LCABL_11320 2.81e-180 501.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli,3F494@33958|Lactobacillaceae 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM AFLMLIMI_00419 543734.LCABL_11310 2.16e-282 772.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,3F3SC@33958|Lactobacillaceae 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK AFLMLIMI_00420 543734.LCABL_11300 2.1e-247 679.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,3F3JS@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N AFLMLIMI_00421 543734.LCABL_11290 5.52e-241 663.0 COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,4HAE6@91061|Bacilli,3F53Y@33958|Lactobacillaceae 91061|Bacilli K Putative sugar-binding domain cggR - - ko:K05311 - - - - ko00000,ko03000 - - - Sugar-bind AFLMLIMI_00424 543734.LCABL_10770 5.97e-132 375.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,3F3M0@33958|Lactobacillaceae 91061|Bacilli O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease AFLMLIMI_00425 543734.LCABL_10760 7.84e-106 305.0 COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,4HKQR@91061|Bacilli,3F74F@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein ohrR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K18906 - M00700,M00702,M00704,M00717 - - ko00000,ko00002,ko01504,ko03000 - - - MarR AFLMLIMI_00426 543734.LCABL_10750 2.27e-218 603.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli,3F4AB@33958|Lactobacillaceae 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N AFLMLIMI_00427 543734.LCABL_10740 2.99e-248 681.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,3F4D5@33958|Lactobacillaceae 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 AFLMLIMI_00428 543734.LCABL_10730 8.53e-213 587.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli,3F4NY@33958|Lactobacillaceae 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 AFLMLIMI_00429 543734.LCABL_10720 2.56e-111 321.0 COG3247@1|root,COG3247@2|Bacteria,1VJ0U@1239|Firmicutes,4HQJ0@91061|Bacilli,3FB5N@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 AFLMLIMI_00430 543734.LCABL_10710 0.0 1900.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,3F4TZ@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran AFLMLIMI_00431 543734.LCABL_10700 0.0 1303.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB AFLMLIMI_00432 543734.LCABL_10690 1.15e-152 429.0 COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,4HA8H@91061|Bacilli,3F4RZ@33958|Lactobacillaceae 91061|Bacilli S HD containing hydrolase-like enzyme yfbR - - ko:K07023 - - - - ko00000 - - - HD_2 AFLMLIMI_00433 543734.LCABL_10680 0.0 1447.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TRAS@1239|Firmicutes,4HC7R@91061|Bacilli,3F5WX@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD AFLMLIMI_00434 1231336.L248_2708 5.14e-119 344.0 COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4HGIE@91061|Bacilli,3F6NW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00435 543734.LCABL_10650 9.54e-215 595.0 COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,4HAPG@91061|Bacilli,3F619@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA AFLMLIMI_00436 543734.LCABL_10640 1.51e-148 418.0 COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,4HDD2@91061|Bacilli,3F6EC@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C AFLMLIMI_00437 543734.LCABL_10630 0.0 1129.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli,3F457@33958|Lactobacillaceae 91061|Bacilli G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV AFLMLIMI_00438 543734.LCABL_10620 1.43e-226 624.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,3F411@33958|Lactobacillaceae 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 AFLMLIMI_00439 543734.LCABL_10610 6.29e-250 686.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli,3F4C8@33958|Lactobacillaceae 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N AFLMLIMI_00440 543734.LCABL_10600 7.94e-202 558.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli,3F42N@33958|Lactobacillaceae 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT AFLMLIMI_00441 543734.LCABL_10590 2.37e-222 613.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,3F3Z3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N AFLMLIMI_00442 543734.LCABL_10580 3.07e-50 161.0 COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,4HNXP@91061|Bacilli,3F7IN@33958|Lactobacillaceae 91061|Bacilli S Mycobacterial 4 TMS phage holin, superfamily IV yvlD - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 AFLMLIMI_00443 543734.LCABL_10570 5.23e-50 159.0 2A2TA@1|root,30R6T@2|Bacteria,1U7RM@1239|Firmicutes,4IHNY@91061|Bacilli,3FA2M@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00444 543734.LCABL_10560 0.0 940.0 COG2433@1|root,COG3595@1|root,COG2433@2|Bacteria,COG3595@2|Bacteria,1TS90@1239|Firmicutes,4HDI6@91061|Bacilli,3F5QQ@33958|Lactobacillaceae 91061|Bacilli S Putative adhesin yvlB - - - - - - - - - - - DUF4097 AFLMLIMI_00445 543734.LCABL_10550 3.82e-156 438.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli,3F46W@33958|Lactobacillaceae 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU AFLMLIMI_00446 543734.LCABL_10540 3.54e-180 501.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran AFLMLIMI_00447 543734.LCABL_10530 9.06e-192 532.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,3F3SY@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran AFLMLIMI_00448 543734.LCABL_10520 1.06e-201 559.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,3F412@33958|Lactobacillaceae 91061|Bacilli P Phosphate transport system permease protein PstA pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 AFLMLIMI_00449 543734.LCABL_10510 4.48e-205 569.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,3F3NI@33958|Lactobacillaceae 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 AFLMLIMI_00450 543734.LCABL_10500 1.76e-196 545.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli,3F4ER@33958|Lactobacillaceae 91061|Bacilli P Phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 AFLMLIMI_00451 543734.LCABL_10490 0.0 1062.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,3F3W2@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like AFLMLIMI_00452 543734.LCABL_10480 1.83e-168 470.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H9KP@91061|Bacilli,3FC91@33958|Lactobacillaceae 91061|Bacilli K response regulator phoP - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C AFLMLIMI_00453 543734.LCABL_10470 1.1e-258 709.0 COG0265@1|root,COG0265@2|Bacteria,1TSBA@1239|Firmicutes,4HA05@91061|Bacilli,3F4TP@33958|Lactobacillaceae 91061|Bacilli O Domain present in PSD-95, Dlg, and ZO-1/2. minJ - - - - - - - - - - - PDZ_2 AFLMLIMI_00455 543734.LCABL_10450 1.28e-160 450.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,3F4JC@33958|Lactobacillaceae 91061|Bacilli D ABC transporter ftsE GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran AFLMLIMI_00456 1423732.BALS01000004_gene1228 8.69e-239 658.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli,3F3SN@33958|Lactobacillaceae 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 AFLMLIMI_00457 543734.LCABL_10420 0.0 1535.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,3F4DH@33958|Lactobacillaceae 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA - - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - Helicase_C,SecA_DEAD,SecA_PP_bind,SecA_SW AFLMLIMI_00458 543734.LCABL_10410 3.24e-126 359.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli,3F40M@33958|Lactobacillaceae 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE AFLMLIMI_00459 568703.LGG_00895 4.32e-104 306.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli,3F714@33958|Lactobacillaceae 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran AFLMLIMI_00460 543734.LCABL_10390 1.57e-299 817.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli,3F3TQ@33958|Lactobacillaceae 91061|Bacilli L Helicase C-terminal domain protein comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII AFLMLIMI_00461 543734.LCABL_10380 3.99e-149 420.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli,3F3SQ@33958|Lactobacillaceae 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 AFLMLIMI_00462 543734.LCABL_10370 7.95e-317 870.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,3F3WX@33958|Lactobacillaceae 91061|Bacilli S Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 AFLMLIMI_00463 543734.LCABL_10360 1.67e-172 486.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA AFLMLIMI_00464 543734.LCABL_10350 8.64e-293 800.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,3F4I4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth AFLMLIMI_00466 543734.LCABL_10340 3.46e-136 385.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli,3F4BI@33958|Lactobacillaceae 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf AFLMLIMI_00467 543734.LCABL_10330 1.15e-169 479.0 COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,4HKW3@91061|Bacilli,3F3SM@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 AFLMLIMI_00468 543734.LCABL_10320 3.01e-166 465.0 COG1028@1|root,COG1028@2|Bacteria,1V0YW@1239|Firmicutes,4ISGK@91061|Bacilli,3FBEA@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 AFLMLIMI_00469 543734.LCABL_10310 1.95e-309 843.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,3F4MU@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C AFLMLIMI_00470 543734.LCABL_10300 2.7e-295 806.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli,3F3SA@33958|Lactobacillaceae 91061|Bacilli S Peptidase M16 inactive domain protein ymfF - - - - - - - - - - - Peptidase_M16_C AFLMLIMI_00471 543734.LCABL_10290 0.0 1420.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,3F3JZ@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma AFLMLIMI_00472 543734.LCABL_10280 4.04e-94 274.0 COG4835@1|root,COG4835@2|Bacteria,1VJ7H@1239|Firmicutes,4HP0P@91061|Bacilli,3F6JB@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1149) - - - - - - - - - - - - DUF1149 AFLMLIMI_00473 543734.LCABL_10270 3.21e-125 355.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli,3F42Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase AFLMLIMI_00474 543734.LCABL_10260 3.44e-200 554.0 COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,4HGQ9@91061|Bacilli,3F4U3@33958|Lactobacillaceae 91061|Bacilli H Methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 AFLMLIMI_00475 543734.LCABL_10250 7.91e-219 604.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F4B8@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA AFLMLIMI_00476 543734.LCABL_10240 1.42e-244 671.0 COG0516@1|root,COG0516@2|Bacteria,1TNYF@1239|Firmicutes,4HA55@91061|Bacilli,3F45K@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaC - 1.7.1.7 ko:K00364 ko00230,map00230 - R01134 RC00457 ko00000,ko00001,ko01000 - - iSB619.SA_RS06660 IMPDH AFLMLIMI_00477 1423732.BALS01000004_gene1205 4.12e-56 174.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 AFLMLIMI_00478 543734.LCABL_10220 2e-82 244.0 COG3731@1|root,COG3731@2|Bacteria,1VGKB@1239|Firmicutes,4HNJN@91061|Bacilli,3F8EZ@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA AFLMLIMI_00479 543734.LCABL_10210 9.35e-254 695.0 COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,3F3RC@33958|Lactobacillaceae 91061|Bacilli G Lactonase, 7-bladed beta-propeller pgl GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 3.1.1.31 ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R02035 RC00537 ko00000,ko00001,ko00002,ko01000 - - - Lactonase AFLMLIMI_00480 543734.LCABL_10200 1.09e-183 512.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli,3F510@33958|Lactobacillaceae 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA AFLMLIMI_00481 543734.LCABL_10190 2.24e-148 417.0 COG3142@1|root,COG3142@2|Bacteria,1TQYI@1239|Firmicutes,4HE1E@91061|Bacilli,3F4NZ@33958|Lactobacillaceae 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC AFLMLIMI_00482 543734.LCABL_10180 1.14e-257 706.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,3FB4B@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE AFLMLIMI_00483 543734.LCABL_10170 4.77e-217 598.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F4AU@33958|Lactobacillaceae 91061|Bacilli G Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 AFLMLIMI_00484 543734.LCABL_10160 1.05e-193 537.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli,3F45D@33958|Lactobacillaceae 91061|Bacilli F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase AFLMLIMI_00485 543734.LCABL_10150 1.19e-158 444.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli,3F452@33958|Lactobacillaceae 91061|Bacilli S RelA SpoT domain protein yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT AFLMLIMI_00486 543734.LCABL_10140 1.79e-138 391.0 COG4116@1|root,COG4116@2|Bacteria,1TTVM@1239|Firmicutes,4I4A3@91061|Bacilli,3F4YS@33958|Lactobacillaceae 91061|Bacilli S CYTH - - - - - - - - - - - - CYTH AFLMLIMI_00487 543734.LCABL_10130 3.71e-147 414.0 COG2761@1|root,COG2761@2|Bacteria,1TQ8K@1239|Firmicutes,4HAI8@91061|Bacilli,3F6QR@33958|Lactobacillaceae 91061|Bacilli Q Thioredoxin yjbH - - - - - - - - - - - Thioredoxin_5 AFLMLIMI_00488 543734.LCABL_10120 2.34e-270 738.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA AFLMLIMI_00489 543734.LCABL_10110 1.31e-310 848.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli,3F4H2@33958|Lactobacillaceae 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 AFLMLIMI_00490 543734.LCABL_10100 5.05e-52 164.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli,3F811@33958|Lactobacillaceae 91061|Bacilli T Belongs to the UPF0237 family XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 AFLMLIMI_00491 543734.LCABL_10090 0.0 895.0 COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,4HG8Z@91061|Bacilli,3F483@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase cpdA - - - - - - - - - - - Metallophos AFLMLIMI_00492 543734.LCABL_10070 9.02e-298 811.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_00493 543734.LCABL_10060 9.78e-112 320.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli,3F6A9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx AFLMLIMI_00494 543734.LCABL_10050 0.0 1050.0 COG0438@1|root,COG0438@2|Bacteria,1UZU7@1239|Firmicutes,4H9N9@91061|Bacilli,3FC17@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE3 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 AFLMLIMI_00495 543734.LCABL_10040 0.0 989.0 COG0438@1|root,COG0438@2|Bacteria,1V1TS@1239|Firmicutes,4HG8T@91061|Bacilli,3FC16@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 tagE2 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Asp1,Glycos_transf_1 AFLMLIMI_00497 543734.LCABL_09530 2.55e-121 345.0 COG1051@1|root,COG1051@2|Bacteria,1VDM3@1239|Firmicutes,4HMI0@91061|Bacilli,3F6RN@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX AFLMLIMI_00498 543734.LCABL_09520 4.78e-183 510.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli,3F480@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N AFLMLIMI_00499 568703.LGG_00853 9.15e-45 144.0 COG3478@1|root,COG3478@2|Bacteria,1VEIV@1239|Firmicutes,4HPKA@91061|Bacilli,3FAC9@33958|Lactobacillaceae 91061|Bacilli S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) yhcC - - ko:K07069 - - - - ko00000 - - - zinc_ribbon_13 AFLMLIMI_00500 543734.LCABL_09510 2.69e-166 465.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,3F41G@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 AFLMLIMI_00501 543734.LCABL_09500 0.0 1012.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli,3F404@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C AFLMLIMI_00502 543734.LCABL_09490 0.0 1676.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,3F46M@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 AFLMLIMI_00504 543734.LCABL_09480 1.82e-155 437.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli,3F5CM@33958|Lactobacillaceae 91061|Bacilli I Acid phosphatase homologues yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 AFLMLIMI_00505 543734.LCABL_09470 3.07e-154 435.0 2C9UQ@1|root,32RPZ@2|Bacteria,1VDDQ@1239|Firmicutes,4HNJB@91061|Bacilli,3F5X9@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 AFLMLIMI_00506 543734.LCABL_09460 0.0 913.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 AFLMLIMI_00507 543734.LCABL_09450 8.05e-106 305.0 COG0789@1|root,COG0789@2|Bacteria,1UD22@1239|Firmicutes,4IFKE@91061|Bacilli,3F8M4@33958|Lactobacillaceae 91061|Bacilli K MerR HTH family regulatory protein - - - - - - - - - - - - MerR_1 AFLMLIMI_00508 543734.LCABL_09440 0.0 934.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator mdr - - - - - - - - - - - MFS_1 AFLMLIMI_00509 543734.LCABL_09430 7.89e-268 735.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli,3F3T0@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N AFLMLIMI_00510 1423816.BACQ01000026_gene919 2.8e-91 273.0 29Q2N@1|root,30B1A@2|Bacteria,1U7D8@1239|Firmicutes,4IH94@91061|Bacilli,3F9EU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00516 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - AFLMLIMI_00517 568703.LGG_00302 1.45e-46 149.0 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,3F8E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00518 543734.LCABL_09340 8.92e-105 302.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli,3F67J@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR AFLMLIMI_00519 543734.LCABL_09330 0.0 1366.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli,3F3R7@33958|Lactobacillaceae 91061|Bacilli M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase AFLMLIMI_00520 543734.LCABL_09320 1.52e-57 178.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli,3F82V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1797) ykuJ - - - - - - - - - - - DUF1797 AFLMLIMI_00521 543734.LCABL_09310 4.48e-277 758.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase araT - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_00523 543734.LCABL_09290 1.58e-220 610.0 COG0392@1|root,COG0392@2|Bacteria,1UY7Z@1239|Firmicutes,4HCG6@91061|Bacilli,3F3UR@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM AFLMLIMI_00524 543734.LCABL_09280 1.32e-251 689.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HB9F@91061|Bacilli,3F47X@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein cpoA GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 2.4.1.208 ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 - R05164,R10865 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 AFLMLIMI_00525 543734.LCABL_09270 1.09e-294 803.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli,3F4H5@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 AFLMLIMI_00527 543734.LCABL_09260 0.0 1011.0 COG0531@1|root,COG0531@2|Bacteria,1TPJH@1239|Firmicutes,4HC13@91061|Bacilli,3F4AR@33958|Lactobacillaceae 91061|Bacilli E amino acid ybeC GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 AFLMLIMI_00528 543734.LCABL_09250 8.3e-123 350.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 AFLMLIMI_00556 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - AFLMLIMI_00557 568703.LGG_00302 1.45e-46 149.0 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,3F8E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00558 543734.LCABL_08920 1.17e-82 244.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli,3F6AN@33958|Lactobacillaceae 91061|Bacilli J general stress protein yugI - - ko:K07570 - - - - ko00000 - - - S1 AFLMLIMI_00559 543734.LCABL_08910 2.99e-140 395.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,3F3TI@33958|Lactobacillaceae 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase AFLMLIMI_00560 543734.LCABL_08900 1.92e-237 652.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,3F3NQ@33958|Lactobacillaceae 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 AFLMLIMI_00561 543734.LCABL_08890 2.26e-115 330.0 COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,4HH4Y@91061|Bacilli,3F6QT@33958|Lactobacillaceae 91061|Bacilli I Phosphatidylglycerophosphatase A pgpA - 3.1.3.27 ko:K01095 ko00564,ko01100,map00564,map01100 - R02029 RC00017 ko00000,ko00001,ko01000 - - - PgpA AFLMLIMI_00562 543734.LCABL_08880 8.69e-149 419.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein dedA - - ko:K03975 - - - - ko00000 - - - SNARE_assoc AFLMLIMI_00563 543734.LCABL_08870 2.62e-145 409.0 COG4478@1|root,COG4478@2|Bacteria,1V7UW@1239|Firmicutes,4HHH4@91061|Bacilli,3F4YP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1461) - - - - - - - - - - - - DUF1461 AFLMLIMI_00564 543734.LCABL_08860 1.34e-186 518.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli,3F49D@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like AFLMLIMI_00565 543734.LCABL_08850 1.02e-150 424.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli,3F66P@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1027) yutD - - - - - - - - - - - DUF1027 AFLMLIMI_00566 543734.LCABL_08840 0.0 918.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,3F4ZD@33958|Lactobacillaceae 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos AFLMLIMI_00567 543734.LCABL_08830 5.01e-146 411.0 COG4186@1|root,COG4186@2|Bacteria,1V40Y@1239|Firmicutes,4HH4J@91061|Bacilli,3F4EX@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos,Metallophos_2 AFLMLIMI_00568 543734.LCABL_08820 3.27e-151 427.0 COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,4HBKX@91061|Bacilli,3F3S6@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibF - - - - - - - - - - - YibE_F AFLMLIMI_00569 543734.LCABL_08810 4.19e-241 664.0 COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,4HCP3@91061|Bacilli,3F3M9@33958|Lactobacillaceae 91061|Bacilli S overlaps another CDS with the same product name yibE - - - - - - - - - - - YibE_F AFLMLIMI_00570 543734.LCABL_08790 9.98e-73 218.0 2C26E@1|root,3424N@2|Bacteria,1VX4A@1239|Firmicutes,4HXT9@91061|Bacilli,3F70Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00571 543734.LCABL_08780 0.0 891.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli,3FC1S@33958|Lactobacillaceae 91061|Bacilli C Glycerophosphoryl diester phosphodiesterase family glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD AFLMLIMI_00572 543734.LCABL_08770 0.0 935.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli,3F3UV@33958|Lactobacillaceae 91061|Bacilli E dipeptidase PepV pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 AFLMLIMI_00573 543734.LCABL_08760 2.79e-175 489.0 COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,3F5HY@33958|Lactobacillaceae 91061|Bacilli H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 AFLMLIMI_00574 543734.LCABL_08750 6.14e-163 456.0 COG1011@1|root,COG1011@2|Bacteria,1TRQ6@1239|Firmicutes,4HKAS@91061|Bacilli,3FBG9@33958|Lactobacillaceae 91061|Bacilli S HAD-hyrolase-like yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 AFLMLIMI_00575 1423732.BALS01000001_gene1381 0.0 1480.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F4ZE@33958|Lactobacillaceae 91061|Bacilli M Penicillin binding protein transpeptidase domain pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase AFLMLIMI_00576 543734.LCABL_08700 3.03e-232 640.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli,3F4AA@33958|Lactobacillaceae 91061|Bacilli K catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AFLMLIMI_00577 543734.LCABL_08690 2.2e-274 749.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli,3F3X5@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 AFLMLIMI_00578 543734.LCABL_08680 7.49e-117 335.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli,3F7V1@33958|Lactobacillaceae 91061|Bacilli S 3H domain yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 AFLMLIMI_00579 543734.LCABL_08670 4.84e-114 328.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,3F8GC@33958|Lactobacillaceae 91061|Bacilli S YtxH-like protein ytxH - - - - - - - - - - - YtxH AFLMLIMI_00580 543734.LCABL_08660 1.49e-46 154.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli,3F6KB@33958|Lactobacillaceae 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 AFLMLIMI_00581 543734.LCABL_08650 1.38e-197 549.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli,3F49U@33958|Lactobacillaceae 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel AFLMLIMI_00582 543734.LCABL_08640 2.79e-200 556.0 COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,4HBE3@91061|Bacilli,3F4QH@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF368) - - - ko:K08974 - - - - ko00000 - - - DUF368 AFLMLIMI_00583 543734.LCABL_08630 9.32e-112 321.0 COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli,3FBMW@33958|Lactobacillaceae 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS AFLMLIMI_00584 543734.LCABL_08620 1.9e-175 489.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HE39@91061|Bacilli,3FCCB@33958|Lactobacillaceae 91061|Bacilli U Major intrinsic protein gla - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP AFLMLIMI_00585 543734.LCABL_08610 1.64e-125 357.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli,3F73R@33958|Lactobacillaceae 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 AFLMLIMI_00586 543734.LCABL_08600 0.0 956.0 COG0127@1|root,COG0796@1|root,COG0127@2|Bacteria,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli,3F446@33958|Lactobacillaceae 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race AFLMLIMI_00587 543734.LCABL_08590 1.66e-111 320.0 COG1719@1|root,COG1719@2|Bacteria,1VD7N@1239|Firmicutes,4HKV3@91061|Bacilli,3F7ZI@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2507) yslB - - - - - - - - - - - DUF2507 AFLMLIMI_00588 543734.LCABL_08580 2.38e-311 847.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli,3F3WE@33958|Lactobacillaceae 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD AFLMLIMI_00589 543734.LCABL_08570 6.97e-49 155.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli,3F7Q1@33958|Lactobacillaceae 91061|Bacilli J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding AFLMLIMI_00590 543734.LCABL_08560 9.86e-304 827.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,3F4KK@33958|Lactobacillaceae 91061|Bacilli M MBOAT, membrane-bound O-acyltransferase family dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT AFLMLIMI_00591 543734.LCABL_08550 0.0 1011.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli,3F49R@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C AFLMLIMI_00592 543734.LCABL_08540 1.04e-27 100.0 2DKST@1|root,30APB@2|Bacteria,1U6XZ@1239|Firmicutes,4IGS5@91061|Bacilli,3F8PK@33958|Lactobacillaceae 91061|Bacilli S D-Ala-teichoic acid biosynthesis protein dltX - - - - - - - - - - - DUF3687 AFLMLIMI_00593 543734.LCABL_08530 3.64e-70 211.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F6Y3@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin AFLMLIMI_00594 543734.LCABL_08520 0.0 1488.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,3F4DX@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr AFLMLIMI_00595 543734.LCABL_08510 3.4e-120 343.0 COG1286@1|root,COG1286@2|Bacteria,1V7U0@1239|Firmicutes,4HIUU@91061|Bacilli,3F6FV@33958|Lactobacillaceae 91061|Bacilli S Colicin V production protein cvpA - - - - - - - - - - - Colicin_V AFLMLIMI_00596 543734.LCABL_08500 2.84e-48 154.0 COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli,3F7ZA@33958|Lactobacillaceae 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA AFLMLIMI_00597 543734.LCABL_08490 1.3e-69 210.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli,3F6X3@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 AFLMLIMI_00598 543734.LCABL_08480 2.67e-96 280.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,3F6NI@33958|Lactobacillaceae 91061|Bacilli J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX AFLMLIMI_00599 1423732.BALS01000001_gene1354 4.89e-58 179.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,3F7EG@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 AFLMLIMI_00601 543734.LCABL_08460 0.0 1748.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,3F3QS@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD AFLMLIMI_00602 543734.LCABL_08450 1.55e-223 616.0 295Z0@1|root,2ZT9T@2|Bacteria,1UJCK@1239|Firmicutes,4IT5A@91061|Bacilli,3F63F@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00603 543734.LCABL_08440 0.0 868.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli,3F4FQ@33958|Lactobacillaceae 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C AFLMLIMI_00604 543734.LCABL_08430 3.03e-229 631.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 AFLMLIMI_00605 543734.LCABL_08420 1.13e-307 839.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli,3F41P@33958|Lactobacillaceae 91061|Bacilli K DRTGG domain ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 AFLMLIMI_00606 543734.LCABL_08410 1.25e-264 724.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,3F44N@33958|Lactobacillaceae 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH AFLMLIMI_00607 543734.LCABL_08400 0.0 995.0 COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3F48G@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N AFLMLIMI_00608 543734.LCABL_08390 2.06e-150 423.0 COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HI7T@91061|Bacilli,3FBMJ@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix diphteria tox regulatory element mntR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA AFLMLIMI_00609 543734.LCABL_08380 0.0 1708.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli,3F3RN@33958|Lactobacillaceae 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adhE - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh,Fe-ADH AFLMLIMI_00610 543734.LCABL_08370 5.25e-87 256.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,4HNK0@91061|Bacilli,3F7EY@33958|Lactobacillaceae 91061|Bacilli U Preprotein translocase yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC AFLMLIMI_00611 543734.LCABL_08360 1.41e-288 786.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli,3F43F@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT AFLMLIMI_00612 543734.LCABL_08350 7.52e-263 719.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli,3F3VG@33958|Lactobacillaceae 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth AFLMLIMI_00613 543734.LCABL_08340 4.54e-241 662.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,3F47S@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N AFLMLIMI_00614 543734.LCABL_08330 2.95e-133 378.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli,3F42W@33958|Lactobacillaceae 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N AFLMLIMI_00615 543734.LCABL_08320 1.3e-136 387.0 COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,4HJDU@91061|Bacilli,3FCEX@33958|Lactobacillaceae 91061|Bacilli S SNARE associated Golgi protein yjbF - - - - - - - - - - - SNARE_assoc AFLMLIMI_00616 543734.LCABL_08310 1.69e-112 322.0 COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,4HFPR@91061|Bacilli,3F4W2@33958|Lactobacillaceae 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS AFLMLIMI_00617 543734.LCABL_08300 4.17e-284 775.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli,3F49P@33958|Lactobacillaceae 91061|Bacilli E methionine synthase, vitamin-B12 independent metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 AFLMLIMI_00618 543734.LCABL_08290 4.49e-97 283.0 2C9NT@1|root,32ZGB@2|Bacteria,1VG8C@1239|Firmicutes,4HN0V@91061|Bacilli,3F749@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 AFLMLIMI_00619 543734.LCABL_08280 7.76e-152 427.0 COG2323@1|root,COG2323@2|Bacteria,1TPNF@1239|Firmicutes,4HF15@91061|Bacilli,3F4F3@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF421) yviA - - - - - - - - - - - DUF421 AFLMLIMI_00620 543734.LCABL_08270 1.02e-197 548.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 AFLMLIMI_00621 543734.LCABL_08260 1.59e-199 555.0 29Q1I@1|root,30B03@2|Bacteria,1U7BX@1239|Firmicutes,4IH77@91061|Bacilli,3F9BB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00622 543734.LCABL_08250 2.52e-199 551.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HACK@91061|Bacilli,3F4XF@33958|Lactobacillaceae 91061|Bacilli S reductase dkgB - - - - - - - - - - - Aldo_ket_red AFLMLIMI_00623 543734.LCABL_08240 1.56e-108 312.0 COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli,3F6JF@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI AFLMLIMI_00624 543734.LCABL_08230 2.4e-231 635.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta ybcH - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 AFLMLIMI_00625 543734.LCABL_08220 2.24e-101 294.0 COG1846@1|root,COG1846@2|Bacteria,1V6TR@1239|Firmicutes,4HXA8@91061|Bacilli,3F66M@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR,MarR_2 AFLMLIMI_00626 543734.LCABL_08210 7.46e-157 440.0 COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,4HQUJ@91061|Bacilli,3FCA0@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase XK27_05175 - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 AFLMLIMI_00627 543734.LCABL_08200 1.14e-255 703.0 COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HAGC@91061|Bacilli,3F3QK@33958|Lactobacillaceae 91061|Bacilli P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family napA - - - - - - - - - - - Na_H_Exchanger AFLMLIMI_00628 543734.LCABL_08190 1.4e-121 347.0 COG1670@1|root,COG1670@2|Bacteria,1UM04@1239|Firmicutes,4ITN9@91061|Bacilli,3FBX6@33958|Lactobacillaceae 91061|Bacilli J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - - AFLMLIMI_00629 568703.LGG_00737 1.69e-58 182.0 29Q8P@1|root,30B7R@2|Bacteria,1U7PN@1239|Firmicutes,4IHKZ@91061|Bacilli,3F9ZK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00630 543734.LCABL_08170 4.48e-230 632.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 AFLMLIMI_00631 543734.LCABL_08160 0.0 1436.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli,3F4Y1@33958|Lactobacillaceae 91061|Bacilli P E1-E2 ATPase yfgQ - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase AFLMLIMI_00632 543734.LCABL_08150 4.06e-107 308.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,3F68C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the NDK family ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK AFLMLIMI_00633 543734.LCABL_08140 1.74e-166 466.0 COG1028@1|root,COG1028@2|Bacteria,1V7U7@1239|Firmicutes,4HIUT@91061|Bacilli,3F491@33958|Lactobacillaceae 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short AFLMLIMI_00634 543734.LCABL_08130 3.86e-78 232.0 29Q7J@1|root,30B6K@2|Bacteria,1U7MR@1239|Firmicutes,4IHIY@91061|Bacilli,3F9X3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00635 543734.LCABL_08120 0.0 1206.0 COG1164@1|root,COG1164@2|Bacteria,1TR7D@1239|Firmicutes,4HA0P@91061|Bacilli,3F3R3@33958|Lactobacillaceae 91061|Bacilli E Oligopeptidase F pepF - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N AFLMLIMI_00636 543734.LCABL_08090 2.66e-112 322.0 COG0716@1|root,COG0716@2|Bacteria 2|Bacteria C FMN binding - - - - - - - - - - - - Flavodoxin_5 AFLMLIMI_00637 543734.LCABL_08080 8.23e-117 334.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,3F5VY@33958|Lactobacillaceae 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin AFLMLIMI_00638 543734.LCABL_08070 3.58e-217 601.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HDX5@91061|Bacilli,3F3S0@33958|Lactobacillaceae 91061|Bacilli S Sodium Bile acid symporter family mleP - - ko:K07088 - - - - ko00000 - - - Mem_trans AFLMLIMI_00639 543734.LCABL_08060 0.0 1095.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,3F3RH@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme mleS - 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 - R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 - - - Malic_M,malic AFLMLIMI_00640 543734.LCABL_08050 5.92e-202 560.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli,3F5D2@33958|Lactobacillaceae 91061|Bacilli K LysR family mleR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_00641 543734.LCABL_08040 2.2e-223 615.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F5FV@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA AFLMLIMI_00642 543734.LCABL_08030 1.7e-81 241.0 COG3189@1|root,COG3189@2|Bacteria,1VABH@1239|Firmicutes,4HKI2@91061|Bacilli,3F715@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function, DUF488 yeaO - - - - - - - - - - - DUF488 AFLMLIMI_00643 543734.LCABL_08020 7.66e-130 369.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,3F4KQ@33958|Lactobacillaceae 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig AFLMLIMI_00644 1423732.BALS01000001_gene1300 1.37e-90 279.0 29Q3E@1|root,30B22@2|Bacteria,1U7EG@1239|Firmicutes,4IHAC@91061|Bacilli,3F9H2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00645 1423816.BACQ01000078_gene2696 5.24e-117 338.0 COG1853@1|root,COG1853@2|Bacteria,1V999@1239|Firmicutes,4HK1X@91061|Bacilli,3FBBG@33958|Lactobacillaceae 91061|Bacilli S Flavin reductase like domain - - - - - - - - - - - - Flavin_Reduct AFLMLIMI_00646 543734.LCABL_07970 5.96e-214 592.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli,3FCFH@33958|Lactobacillaceae 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans AFLMLIMI_00647 568703.LGG_00718 1.7e-64 201.0 29Q6R@1|root,30B5R@2|Bacteria,1U7KG@1239|Firmicutes,4IHHI@91061|Bacilli,3F9VA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00648 543734.LCABL_07950 9.86e-146 410.0 COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3F3JG@33958|Lactobacillaceae 91061|Bacilli K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 AFLMLIMI_00649 568703.LGG_00716 1.58e-33 115.0 29QE7@1|root,30BDI@2|Bacteria,1U7YK@1239|Firmicutes,4IHVZ@91061|Bacilli,3FABT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00650 543734.LCABL_07930 5.77e-267 732.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter XK27_05220 - - - - - - - - - - - AI-2E_transport AFLMLIMI_00651 543734.LCABL_07920 1.79e-104 303.0 2CCJZ@1|root,303JM@2|Bacteria,1U58T@1239|Firmicutes,4IF00@91061|Bacilli,3F565@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00652 543734.LCABL_07910 1.32e-71 216.0 2BQ7I@1|root,32J28@2|Bacteria,1U7KB@1239|Firmicutes,4IHHD@91061|Bacilli,3F9V1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00654 543734.LCABL_07900 3.9e-243 668.0 COG0604@1|root,COG0604@2|Bacteria,1TRNC@1239|Firmicutes,4HATC@91061|Bacilli,3F48F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 AFLMLIMI_00655 568703.LGG_00711 5.74e-54 170.0 2AVVX@1|root,31MPR@2|Bacteria,1U7Q2@1239|Firmicutes,4IHMD@91061|Bacilli,3FA04@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00656 543734.LCABL_07880 2.7e-62 191.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HMY5@91061|Bacilli,3F7IR@33958|Lactobacillaceae 91061|Bacilli S Sugar efflux transporter for intercellular exchange ygbF - - - - - - - - - - - MtN3_slv AFLMLIMI_00657 543734.LCABL_07870 1.17e-77 231.0 COG1695@1|root,COG1695@2|Bacteria,1VA94@1239|Firmicutes,4HKJS@91061|Bacilli,3F6I1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR AFLMLIMI_00658 543734.LCABL_07860 1.86e-244 672.0 COG1476@1|root,COG1476@2|Bacteria,1V36C@1239|Firmicutes,4IT3D@91061|Bacilli,3F65G@33958|Lactobacillaceae 91061|Bacilli K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_3 AFLMLIMI_00661 1138822.PL11_00285 8.37e-24 94.4 28WF1@1|root,2ZIF8@2|Bacteria,1W2PF@1239|Firmicutes,4HZUK@91061|Bacilli,3F8BE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00662 388919.SSA_0615 1.29e-07 62.0 COG1396@1|root,COG1396@2|Bacteria,1UA46@1239|Firmicutes,4IKDX@91061|Bacilli,1WREM@1305|Streptococcus sanguinis 91061|Bacilli K Transcriptional regulator RggD rggD - - - - - - - - - - - - AFLMLIMI_00663 1423806.JCM15457_1781 1.68e-23 93.6 COG1396@1|root,COG1396@2|Bacteria,1V3D7@1239|Firmicutes,4IGD5@91061|Bacilli,3F83A@33958|Lactobacillaceae 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 AFLMLIMI_00664 1423806.JCM15457_1782 1.89e-70 265.0 COG1196@1|root,COG1196@2|Bacteria,1UKKS@1239|Firmicutes,4ITJ9@91061|Bacilli 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - - AFLMLIMI_00667 543734.LCABL_07830 1.84e-262 719.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F9FE@33958|Lactobacillaceae 91061|Bacilli C IMP dehydrogenase / GMP reductase domain lldD - 1.13.12.4 ko:K00467 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh AFLMLIMI_00668 543734.LCABL_07820 2.41e-156 438.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli,3F4H1@33958|Lactobacillaceae 91061|Bacilli C Nitroreductase family ydgI - - - - - - - - - - - Nitroreductase AFLMLIMI_00669 543734.LCABL_07810 1.41e-204 565.0 COG4689@1|root,COG4689@2|Bacteria,1VW7Z@1239|Firmicutes,4I17W@91061|Bacilli,3F5RQ@33958|Lactobacillaceae 91061|Bacilli Q Acetoacetate decarboxylase (ADC) adc - 4.1.1.4 ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 M00088 R01366 RC00040 ko00000,ko00001,ko00002,ko01000 - - - ADC AFLMLIMI_00670 543734.LCABL_07800 1.31e-207 573.0 COG4221@1|root,COG4221@2|Bacteria,1UI5T@1239|Firmicutes,4HI5J@91061|Bacilli,3FBSB@33958|Lactobacillaceae 91061|Bacilli S KR domain - - - - - - - - - - - - adh_short AFLMLIMI_00671 543734.LCABL_07790 0.0 943.0 COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,4HQKK@91061|Bacilli,3F5KD@33958|Lactobacillaceae 91061|Bacilli QT PucR C-terminal helix-turn-helix domain - - - - - - - - - - - - HTH_30 AFLMLIMI_00672 543734.LCABL_07780 2.42e-88 259.0 COG4918@1|root,COG4918@2|Bacteria,1VK6M@1239|Firmicutes,4HRFS@91061|Bacilli,3F7JD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family - - - - - - - - - - - - Fe-S_biosyn AFLMLIMI_00673 543734.LCABL_07770 5.8e-307 837.0 COG5002@1|root,COG5002@2|Bacteria,1TS5K@1239|Firmicutes,4H9Y1@91061|Bacilli,3F49T@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain ciaH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA AFLMLIMI_00674 543734.LCABL_07760 3.91e-159 446.0 COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli,3F3TH@33958|Lactobacillaceae 91061|Bacilli K cheY-homologous receiver domain ciaR - - ko:K14983 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C AFLMLIMI_00675 543734.LCABL_07750 3.08e-93 272.0 2DTIF@1|root,33KHD@2|Bacteria,1UIGW@1239|Firmicutes,4ISGW@91061|Bacilli,3F7X1@33958|Lactobacillaceae 91061|Bacilli S GtrA-like protein - - - - - - - - - - - - GtrA AFLMLIMI_00676 543734.LCABL_07740 0.0 1340.0 COG1807@1|root,COG1807@2|Bacteria,1TPGI@1239|Firmicutes,4HCEY@91061|Bacilli,3F5B1@33958|Lactobacillaceae 91061|Bacilli M Dolichyl-phosphate-mannose-protein mannosyltransferase ykcB - - - - - - - - - - - PMT_2 AFLMLIMI_00677 543734.LCABL_07730 8.07e-233 640.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykcC - - ko:K20534 - - - - ko00000,ko01000,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 AFLMLIMI_00678 543734.LCABL_07720 0.0 1587.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F588@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus pacL3 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 AFLMLIMI_00679 543734.LCABL_07710 5.82e-223 615.0 COG0604@1|root,COG0604@2|Bacteria,1TPGR@1239|Firmicutes,4HACF@91061|Bacilli,3F5R8@33958|Lactobacillaceae 91061|Bacilli C Zinc-binding dehydrogenase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N AFLMLIMI_00680 543734.LCABL_07700 1.13e-178 499.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein - - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran AFLMLIMI_00681 543734.LCABL_07690 2.78e-207 576.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family WQ51_06230 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 AFLMLIMI_00682 543734.LCABL_07680 2.94e-213 591.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter XK27_00670 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind AFLMLIMI_00683 543734.LCABL_07660 1.77e-212 588.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F4MI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter substrate binding protein XK27_00670 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind AFLMLIMI_00684 543734.LCABL_07640 0.0 1537.0 COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,3F43A@33958|Lactobacillaceae 91061|Bacilli G hydrolase, family 3 bglB - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C AFLMLIMI_00685 543734.LCABL_07630 2.31e-148 418.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HVUN@91061|Bacilli,3F5K7@33958|Lactobacillaceae 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 AFLMLIMI_00687 543734.LCABL_07610 1.12e-250 688.0 29Q0Q@1|root,30AZ6@2|Bacteria,1U7AN@1239|Firmicutes,4IH5M@91061|Bacilli,3F980@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00688 543734.LCABL_07600 2.24e-197 546.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin AFLMLIMI_00689 543734.LCABL_07590 7.83e-153 429.0 COG4832@1|root,COG4832@2|Bacteria,1U5NN@1239|Firmicutes,4IFD7@91061|Bacilli,3F684@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - AFLMLIMI_00690 543734.LCABL_07580 1.06e-112 324.0 COG3247@1|root,COG3247@2|Bacteria,1VK2X@1239|Firmicutes,4HQFY@91061|Bacilli,3F7G9@33958|Lactobacillaceae 91061|Bacilli S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 AFLMLIMI_00692 543734.LCABL_07560 3.55e-155 436.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HIR3@91061|Bacilli,3F6XY@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold yrkL - - - - - - - - - - - Flavodoxin_2 AFLMLIMI_00693 543734.LCABL_07550 2.23e-191 530.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 AFLMLIMI_00694 543734.LCABL_07540 2.18e-270 739.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,3FCD0@33958|Lactobacillaceae 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 AFLMLIMI_00696 543734.LCABL_07530 7.42e-112 321.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7DR@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp1 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 AFLMLIMI_00697 543734.LCABL_07510 6.8e-21 82.8 29PWB@1|root,30AUN@2|Bacteria,1U74I@1239|Firmicutes,4IGZ5@91061|Bacilli,3F8YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00698 543734.LCABL_07500 0.0 1635.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli,3F3TE@33958|Lactobacillaceae 91061|Bacilli L Putative exonuclease SbcCD, C subunit sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C AFLMLIMI_00699 543734.LCABL_07490 3.77e-269 736.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli,3F4A9@33958|Lactobacillaceae 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C AFLMLIMI_00700 543734.LCABL_07480 5.5e-117 337.0 COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,4HJ9I@91061|Bacilli,3F658@33958|Lactobacillaceae 91061|Bacilli S HAD hydrolase, family IA, variant - - - - - - - - - - - - HAD_2 AFLMLIMI_00701 543734.LCABL_07470 4.13e-181 504.0 COG1349@1|root,COG1349@2|Bacteria,1V097@1239|Firmicutes,4HGA7@91061|Bacilli,3F5GM@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K02530 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AFLMLIMI_00702 543734.LCABL_07460 1.25e-96 281.0 COG0698@1|root,COG0698@2|Bacteria,1V5VZ@1239|Firmicutes,4HJK6@91061|Bacilli,3F6CQ@33958|Lactobacillaceae 91061|Bacilli G Ribose/Galactose Isomerase lacA - 5.3.1.26 ko:K01819 ko00052,ko01100,map00052,map01100 - R03240 RC00376 ko00000,ko00001,ko01000 - - - LacAB_rpiB AFLMLIMI_00703 543734.LCABL_07450 4.53e-122 348.0 COG0698@1|root,COG0698@2|Bacteria,1U9Y4@1239|Firmicutes,4HE4C@91061|Bacilli,3F41M@33958|Lactobacillaceae 91061|Bacilli G Ribose/Galactose Isomerase lacB - 5.3.1.26 ko:K01819 ko00052,ko01100,map00052,map01100 - R03240 RC00376 ko00000,ko00001,ko01000 - - - LacAB_rpiB AFLMLIMI_00704 543734.LCABL_07440 2.95e-239 657.0 COG3684@1|root,COG3684@2|Bacteria,1TQRR@1239|Firmicutes,4HBS9@91061|Bacilli,3F3UA@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aldolase LacD family lacD - 4.1.2.40 ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC AFLMLIMI_00705 543734.LCABL_07430 3.52e-225 620.0 COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,4HAGR@91061|Bacilli,3F56E@33958|Lactobacillaceae 91061|Bacilli H pfkB family carbohydrate kinase lacC - 2.7.1.144 ko:K00917 ko00052,ko01100,map00052,map01100 - R03236 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB AFLMLIMI_00706 543734.LCABL_07420 7.44e-159 445.0 28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,4HMHN@91061|Bacilli,3F6AW@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4867) - - - - - - - - - - - - DUF4867 AFLMLIMI_00707 543734.LCABL_07410 2.82e-36 122.0 29QNH@1|root,30BN4@2|Bacteria,1U8CP@1239|Firmicutes,4IIAN@91061|Bacilli,3FAUA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00708 543734.LCABL_07400 0.0 924.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HBJG@91061|Bacilli,3FCCG@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component gatC - - ko:K20114 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5 - - EIIC-GAT AFLMLIMI_00709 543734.LCABL_07390 2.68e-67 204.0 COG3414@1|root,COG3414@2|Bacteria,1VACD@1239|Firmicutes,4HKHR@91061|Bacilli,3F732@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.204 ko:K20113 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5 - - PTS_IIB AFLMLIMI_00710 543734.LCABL_07380 2.36e-111 320.0 COG1762@1|root,COG1762@2|Bacteria,1VBW9@1239|Firmicutes,4IR84@91061|Bacilli,3FBMU@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.204 ko:K20112 ko02060,map02060 M00807 R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5 - - PTS_EIIA_2 AFLMLIMI_00713 543734.LCABL_07340 7.09e-253 692.0 COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,3F48R@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim AFLMLIMI_00714 543734.LCABL_07330 3.41e-218 604.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator msmR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AFLMLIMI_00715 543734.LCABL_07320 0.0 979.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli,3F4D8@33958|Lactobacillaceae 91061|Bacilli G UDP-glucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf AFLMLIMI_00716 543734.LCABL_07310 4.24e-247 677.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,3F3YF@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd AFLMLIMI_00717 543734.LCABL_07300 5.71e-283 773.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli,3F3Q9@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg AFLMLIMI_00718 1423732.BALS01000046_gene2619 2.75e-177 493.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,4HGSR@91061|Bacilli,3FBSG@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 AFLMLIMI_00719 543734.LCABL_07240 0.0 1013.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N AFLMLIMI_00720 1423816.BACQ01000077_gene2626 0.0 1041.0 COG0578@1|root,COG0578@2|Bacteria,1TQJN@1239|Firmicutes,4HAG8@91061|Bacilli,3F5BS@33958|Lactobacillaceae 91061|Bacilli C C-terminal domain of alpha-glycerophosphate oxidase glpD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.1.3.21,1.1.5.3 ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 - R00846,R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C AFLMLIMI_00721 543734.LCABL_07210 3.84e-170 474.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HAWP@91061|Bacilli,3F4J6@33958|Lactobacillaceae 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family glpF - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP AFLMLIMI_00722 543734.LCABL_07200 1.8e-145 409.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli,3F4WH@33958|Lactobacillaceae 91061|Bacilli L Uracil-DNA glycosylase ung2 - - - - - - - - - - - UDG AFLMLIMI_00723 543734.LCABL_07190 0.0 1076.0 COG0249@1|root,COG0249@2|Bacteria,1TPJP@1239|Firmicutes,4HD9G@91061|Bacilli,3F5Q9@33958|Lactobacillaceae 91061|Bacilli L ATPase domain of DNA mismatch repair MUTS family - - - - - - - - - - - - MutS_V AFLMLIMI_00724 543734.LCABL_07180 0.0 1075.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli,3F3ZJ@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn AFLMLIMI_00728 1423816.BACQ01000063_gene2437 5.74e-106 310.0 COG1131@1|root,COG1131@2|Bacteria,1VA12@1239|Firmicutes,4HMB1@91061|Bacilli,3F6Q1@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00731 543734.LCABL_07160 5.1e-150 427.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli,3F3Y8@33958|Lactobacillaceae 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2,Endonuclease_NS AFLMLIMI_00732 543734.LCABL_07150 2.22e-154 434.0 COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,4HHDI@91061|Bacilli,3FB83@33958|Lactobacillaceae 91061|Bacilli S MgtC family yqgG - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC AFLMLIMI_00733 543734.LCABL_07140 3.26e-226 623.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli,3F45Z@33958|Lactobacillaceae 91061|Bacilli P Peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal AFLMLIMI_00734 543734.LCABL_07130 3.8e-316 861.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli,3F3X1@33958|Lactobacillaceae 91061|Bacilli P ammonium transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp AFLMLIMI_00735 543734.LCABL_07120 2.79e-201 559.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F3WU@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 AFLMLIMI_00736 543734.LCABL_07110 1.06e-69 210.0 COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKGZ@91061|Bacilli,3F6YC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0145 family ybjQ - - - - - - - - - - - YbjQ_1 AFLMLIMI_00737 543734.LCABL_07100 5.47e-159 445.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli,3F7DZ@33958|Lactobacillaceae 91061|Bacilli P Eukaryotic-type carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase AFLMLIMI_00738 543734.LCABL_07090 6.15e-188 521.0 COG4814@1|root,COG4814@2|Bacteria,1VXHZ@1239|Firmicutes,4HX59@91061|Bacilli,3F75V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 AFLMLIMI_00739 543734.LCABL_07080 2.25e-209 579.0 COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,4HB5U@91061|Bacilli,3F58G@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990,ko:K11050 ko02010,map02010 M00254,M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.130 - - ABC_tran AFLMLIMI_00740 543734.LCABL_07070 8.93e-191 531.0 COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HJK7@91061|Bacilli,3FCET@33958|Lactobacillaceae 91061|Bacilli V ABC-2 type transporter - - - ko:K11051 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC2_membrane,ABC2_membrane_3 AFLMLIMI_00741 543734.LCABL_07060 1.2e-95 279.0 COG3279@1|root,COG3279@2|Bacteria,1W04J@1239|Firmicutes,4HRMI@91061|Bacilli,3F6TA@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR AFLMLIMI_00742 543734.LCABL_07050 2.72e-78 234.0 2C5CN@1|root,2ZGHZ@2|Bacteria,1W5A8@1239|Firmicutes,4I240@91061|Bacilli,3F89I@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 AFLMLIMI_00743 543734.LCABL_07040 0.0 1237.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli,3F42V@33958|Lactobacillaceae 91061|Bacilli P Sodium proton antiporter nhaK - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger AFLMLIMI_00744 543734.LCABL_07030 0.0 1090.0 29PJG@1|root,30AHM@2|Bacteria,1U6PG@1239|Firmicutes,4IGGF@91061|Bacilli,3F896@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3800) - - - - - - - - - - - - DUF3800 AFLMLIMI_00745 543734.LCABL_07020 4.52e-316 862.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli,3F3YD@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yifK - - ko:K03293 - - - - ko00000 2.A.3.1 - - AA_permease AFLMLIMI_00746 543734.LCABL_07010 5.5e-202 559.0 COG0656@1|root,COG0656@2|Bacteria,1VSK5@1239|Firmicutes,4HT3F@91061|Bacilli,3FBX5@33958|Lactobacillaceae 91061|Bacilli S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red AFLMLIMI_00748 543734.LCABL_07000 2.73e-147 414.0 COG0702@1|root,COG0702@2|Bacteria,1TQFS@1239|Firmicutes,4HDA2@91061|Bacilli,3F521@33958|Lactobacillaceae 91061|Bacilli GM NAD(P)H-binding ylbE - - - - - - - - - - - NAD_binding_10 AFLMLIMI_00749 543734.LCABL_06990 0.0 963.0 COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,3F53D@33958|Lactobacillaceae 91061|Bacilli S ABC transporter yjcA - - ko:K19350 ko02010,map02010 - - - ko00000,ko00001,ko01504,ko02000 3.A.1.121 - - ABC_tran,ABC_tran_Xtn AFLMLIMI_00750 543734.LCABL_06980 1.37e-99 289.0 COG1764@1|root,COG1764@2|Bacteria,1VBJ0@1239|Firmicutes,4HNBY@91061|Bacilli,3F664@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC AFLMLIMI_00751 543734.LCABL_06970 2.35e-86 255.0 29PCC@1|root,30AAK@2|Bacteria,1U6ED@1239|Firmicutes,4IG65@91061|Bacilli,3F7QE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00752 641146.HMPREF9020_01154 4.51e-300 818.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_00753 1423732.BALS01000009_gene740 3.08e-43 140.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7RG@33958|Lactobacillaceae 91061|Bacilli K 'Cold-shock' DNA-binding domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD AFLMLIMI_00754 543734.LCABL_06940 0.0 868.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli,3F4DS@33958|Lactobacillaceae 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N AFLMLIMI_00755 543734.LCABL_06930 1.13e-221 611.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F4MZ@33958|Lactobacillaceae 91061|Bacilli C lactate/malate dehydrogenase, alpha/beta C-terminal domain ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N AFLMLIMI_00756 543734.LCABL_06920 0.0 930.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AFLMLIMI_00757 543734.LCABL_06910 1.51e-283 778.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli,3FB7N@33958|Lactobacillaceae 91061|Bacilli U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF AFLMLIMI_00758 543734.LCABL_06900 0.0 1219.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system treB - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AFLMLIMI_00759 543734.LCABL_06890 0.0 1137.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C AFLMLIMI_00760 543734.LCABL_06880 5.43e-167 467.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli,3F62J@33958|Lactobacillaceae 91061|Bacilli K UTRA treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_00761 543734.LCABL_06870 7.86e-285 780.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,3F4XT@33958|Lactobacillaceae 91061|Bacilli P Major Facilitator Superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 AFLMLIMI_00762 543734.LCABL_06860 0.0 1136.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147,ko:K18892 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_00763 543734.LCABL_06850 0.0 1083.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F3SP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_09600 - - ko:K06147,ko:K18891 ko02010,map02010 M00708 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.109,3.A.1.135,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_00764 543734.LCABL_06830 0.0 1528.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,3F3VW@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 AFLMLIMI_00765 543734.LCABL_06820 1.86e-209 578.0 COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,4HGHI@91061|Bacilli,3FB7R@33958|Lactobacillaceae 91061|Bacilli C Methylenetetrahydrofolate reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR AFLMLIMI_00766 543734.LCABL_06810 1.75e-190 529.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli,3F3V7@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin AFLMLIMI_00767 543734.LCABL_06800 4.75e-113 326.0 COG4720@1|root,COG4720@2|Bacteria,1V52B@1239|Firmicutes,4HJY9@91061|Bacilli,3FBCH@33958|Lactobacillaceae 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS AFLMLIMI_00768 543734.LCABL_06790 3.03e-186 518.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCT1@91061|Bacilli,3F5PG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter CcmA5 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00769 543734.LCABL_06780 0.0 1085.0 28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,4HBRI@91061|Bacilli,3F6T9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00770 543734.LCABL_06770 6.94e-225 621.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family yicL - - - - - - - - - - - EamA AFLMLIMI_00771 543734.LCABL_06760 0.0 1324.0 COG4886@1|root,COG4886@2|Bacteria,1UVV3@1239|Firmicutes,4I2C6@91061|Bacilli,3F8E0@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - WxL AFLMLIMI_00772 543734.LCABL_06750 3.2e-134 384.0 COG5492@1|root,COG5492@2|Bacteria,1W54S@1239|Firmicutes,4IF30@91061|Bacilli,3F5H0@33958|Lactobacillaceae 91061|Bacilli N WxL domain surface cell wall-binding - - - - - - - - - - - - WxL AFLMLIMI_00773 543734.LCABL_06740 4.46e-74 222.0 29QPU@1|root,30BPI@2|Bacteria,1U8F4@1239|Firmicutes,4IID0@91061|Bacilli,3FAWZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00774 543734.LCABL_06730 1.66e-154 435.0 2DDU7@1|root,2ZJAU@2|Bacteria 2|Bacteria S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL AFLMLIMI_00775 543734.LCABL_06710 3.8e-249 710.0 COG4886@1|root,COG4886@2|Bacteria,1UVV2@1239|Firmicutes,4I2C5@91061|Bacilli,3F806@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - WxL AFLMLIMI_00776 543734.LCABL_06700 1.46e-57 181.0 2AIBJ@1|root,318SM@2|Bacteria,1U7ZW@1239|Firmicutes,4IHXA@91061|Bacilli,3FAD9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - Gram_pos_anchor AFLMLIMI_00777 543734.LCABL_06690 4.95e-225 622.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein - - - - - - - - - - - - DUF3324,DUF916 AFLMLIMI_00778 543734.LCABL_06680 3.26e-151 426.0 2DDU7@1|root,2ZJAU@2|Bacteria,1UM02@1239|Firmicutes 1239|Firmicutes S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL AFLMLIMI_00779 543734.LCABL_06660 0.0 878.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans AFLMLIMI_00780 1423816.BACQ01000040_gene1607 7.5e-44 159.0 29Q72@1|root,30B62@2|Bacteria,1U7KY@1239|Firmicutes,4IHI1@91061|Bacilli,3F9VZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00781 543734.LCABL_06640 1.42e-157 443.0 COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,4H9N1@91061|Bacilli,3F4QR@33958|Lactobacillaceae 91061|Bacilli E ABC transporter tcyB - - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 AFLMLIMI_00782 543734.LCABL_06630 6.84e-186 517.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,3F4MH@33958|Lactobacillaceae 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family tcyA - - ko:K02424 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 AFLMLIMI_00783 543734.LCABL_06620 1.13e-273 748.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli,3F3Y2@33958|Lactobacillaceae 91061|Bacilli E cystathionine mccB GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008284,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0042127,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048518,GO:0048522,GO:0050667,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.4.1.1,4.4.1.2,4.4.1.8 ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00782,R01001,R01283,R01286,R02408,R04941 RC00056,RC00069,RC00348,RC00382,RC00487,RC00488,RC00710,RC01245,RC02303,RC02814 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27250 Cys_Met_Meta_PP AFLMLIMI_00785 1423724.BAMM01000001_gene101 2.14e-24 100.0 28WK8@1|root,32UJK@2|Bacteria,1VDM0@1239|Firmicutes,4HN9X@91061|Bacilli,3FBAY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00786 543734.LCABL_05450 2.2e-222 613.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli,3F4VD@33958|Lactobacillaceae 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP AFLMLIMI_00787 543734.LCABL_05440 6.47e-205 565.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,3F5CA@33958|Lactobacillaceae 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to metA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS AFLMLIMI_00788 543734.LCABL_05430 1.72e-214 592.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3F4WM@33958|Lactobacillaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N AFLMLIMI_00789 543734.LCABL_05420 6.33e-275 754.0 COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,4HNF2@91061|Bacilli,3FBTT@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 AFLMLIMI_00790 543734.LCABL_05410 2.17e-211 584.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,3F5MZ@33958|Lactobacillaceae 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N AFLMLIMI_00791 1423816.BACQ01000064_gene2507 1.26e-180 504.0 COG1028@1|root,COG1028@2|Bacteria,1TRFT@1239|Firmicutes,4HCX7@91061|Bacilli,3F4HT@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 AFLMLIMI_00792 1423732.BALS01000043_gene2705 3.28e-206 570.0 COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,4HCNS@91061|Bacilli,3F5RA@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 AFLMLIMI_00793 543734.LCABL_05370 1.93e-210 582.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HFSV@91061|Bacilli,3F48I@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_00794 543734.LCABL_05360 1.66e-117 336.0 COG3477@1|root,COG3477@2|Bacteria,1VX0K@1239|Firmicutes,4HX2R@91061|Bacilli,3F6A5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1440) - - - ko:K08996 - - - - ko00000 - - - DUF1440 AFLMLIMI_00795 543734.LCABL_05350 0.0 948.0 COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,4HBIP@91061|Bacilli,3FCAH@33958|Lactobacillaceae 91061|Bacilli E amino acid ycaM - - - - - - - - - - - AA_permease_2 AFLMLIMI_00796 543734.LCABL_05340 0.0 1671.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli,3F3UH@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 AFLMLIMI_00797 543734.LCABL_05330 0.0 3016.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtP - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - PA,Peptidase_S8,SLAP,fn3_5 AFLMLIMI_00798 543734.LCABL_05320 0.0 3521.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtP - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - PA,Peptidase_S8,SLAP,fn3_5 AFLMLIMI_00799 543734.LCABL_05310 8.02e-118 339.0 2CZFI@1|root,30A49@2|Bacteria,1U667@1239|Firmicutes,4IFWD@91061|Bacilli,3F761@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00800 543734.LCABL_05300 8.88e-268 734.0 28IVE@1|root,2Z8TU@2|Bacteria,1UYXD@1239|Firmicutes,4HMX1@91061|Bacilli,3F500@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 AFLMLIMI_00801 543734.LCABL_05290 2.78e-180 504.0 COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,4HD67@91061|Bacilli,3F5Y2@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - - - - - - - - - - ABC_tran AFLMLIMI_00802 543734.LCABL_05270 9.46e-249 684.0 COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,4HBC0@91061|Bacilli,3F4NF@33958|Lactobacillaceae 91061|Bacilli T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K20487 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA AFLMLIMI_00803 543734.LCABL_05260 9.4e-165 461.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HHWT@91061|Bacilli,3F536@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal - - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C AFLMLIMI_00804 543734.LCABL_05250 0.0 1029.0 28IHZ@1|root,2Z8J5@2|Bacteria,1TQV6@1239|Firmicutes,4HPC9@91061|Bacilli,3F5NC@33958|Lactobacillaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - AFLMLIMI_00805 543734.LCABL_05240 6.5e-162 454.0 COG1131@1|root,COG1131@2|Bacteria,1TRTC@1239|Firmicutes,4HG0J@91061|Bacilli,3F59T@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities XK27_12140 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00806 543734.LCABL_05230 1.5e-256 703.0 COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HHRS@91061|Bacilli,3FCAC@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase AFLMLIMI_00807 543734.LCABL_05220 1.25e-236 651.0 COG4932@1|root,COG4932@2|Bacteria,1W6HP@1239|Firmicutes,4HZUT@91061|Bacilli,3F9E7@33958|Lactobacillaceae 91061|Bacilli M LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor AFLMLIMI_00808 543734.LCABL_05210 4.1e-162 454.0 COG4932@1|root,COG4932@2|Bacteria,1U7CB@1239|Firmicutes,4IH7P@91061|Bacilli,3F9CF@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - AFLMLIMI_00809 543734.LCABL_05200 0.0 1767.0 COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,1V87P@1239|Firmicutes,4HA8Y@91061|Bacilli,3F3PM@33958|Lactobacillaceae 91061|Bacilli M Cna protein B-type domain yvcC - - - - - - - - - - - Cna_B,VWA,VWA_2 AFLMLIMI_00810 543734.LCABL_05190 7.58e-134 379.0 COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,4HDX2@91061|Bacilli,3F51V@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain tnpR1 - - - - - - - - - - - HTH_24,HTH_7,Resolvase AFLMLIMI_00811 543734.LCABL_05180 0.0 1223.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HDAQ@91061|Bacilli,3F75H@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 AFLMLIMI_00812 543734.LCABL_05170 4.8e-66 201.0 COG1440@1|root,COG1440@2|Bacteria,1VFYT@1239|Firmicutes,4HPS6@91061|Bacilli,3F8GJ@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit licB2 - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB AFLMLIMI_00813 543734.LCABL_05160 2.19e-290 793.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HBC9@91061|Bacilli,3F5XI@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_00814 543734.LCABL_05150 1.54e-75 226.0 COG1447@1|root,COG1447@2|Bacteria,1VCD8@1239|Firmicutes,4HPQW@91061|Bacilli,3F8H7@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA AFLMLIMI_00815 543734.LCABL_05140 0.0 997.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family - - 3.2.1.21,3.2.1.85,3.2.1.86 ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AFLMLIMI_00816 543734.LCABL_05130 7.98e-123 352.0 COG2364@1|root,COG2364@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - YitT_membrane AFLMLIMI_00817 543734.LCABL_05120 1.85e-75 225.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,3F7S1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family ydeP - - - - - - - - - - - HxlR AFLMLIMI_00818 543734.LCABL_05110 7.12e-255 697.0 COG0604@1|root,COG0604@2|Bacteria,1TRNC@1239|Firmicutes,4HATC@91061|Bacilli,3F48F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily qor - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 AFLMLIMI_00819 543734.LCABL_05100 1.4e-203 563.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,3FB4S@33958|Lactobacillaceae 91061|Bacilli S reductase - - - - - - - - - - - - Aldo_ket_red AFLMLIMI_00820 543734.LCABL_05090 1.68e-98 286.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4HH53@91061|Bacilli,3F7ID@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 AFLMLIMI_00821 543734.LCABL_05080 0.0 866.0 COG0531@1|root,COG0531@2|Bacteria,1V01X@1239|Firmicutes,4HVQJ@91061|Bacilli,3F7SQ@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease,AA_permease_2 AFLMLIMI_00822 543734.LCABL_05070 2.06e-283 773.0 COG2159@1|root,COG2159@2|Bacteria,1V9T6@1239|Firmicutes,4HKS1@91061|Bacilli 91061|Bacilli S Amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 AFLMLIMI_00823 543734.LCABL_05060 0.0 882.0 COG0174@1|root,COG0174@2|Bacteria,1U0IB@1239|Firmicutes,4HTS7@91061|Bacilli 91061|Bacilli E Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N_2 AFLMLIMI_00824 543734.LCABL_05050 3.85e-182 506.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3F4PK@33958|Lactobacillaceae 91061|Bacilli S peptidase C26 puuD - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 AFLMLIMI_00825 543734.LCABL_05040 3.17e-185 514.0 COG2227@1|root,COG2227@2|Bacteria,1UIIR@1239|Firmicutes,4ISJH@91061|Bacilli,3F5MJ@33958|Lactobacillaceae 91061|Bacilli H Protein of unknown function (DUF1698) - - - - - - - - - - - - Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 AFLMLIMI_00826 543734.LCABL_05030 5.8e-248 680.0 COG1680@1|root,COG1680@2|Bacteria,1UZUZ@1239|Firmicutes,4IPQ5@91061|Bacilli,3F969@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Beta-lactamase,DUF3471 AFLMLIMI_00827 543734.LCABL_05020 0.0 1147.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family cidC - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - iSB619.SA_RS13340 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AFLMLIMI_00828 1423816.BACQ01000064_gene2484 5.36e-215 593.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F4EF@33958|Lactobacillaceae 91061|Bacilli G Fructose-1,6-bisphosphate aldolase, class II fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase AFLMLIMI_00829 543734.LCABL_05000 2.28e-138 390.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco AFLMLIMI_00830 543734.LCABL_04990 4.89e-139 393.0 COG0640@1|root,COG0640@2|Bacteria,1V007@1239|Firmicutes,4HDXJ@91061|Bacilli,3F7E5@33958|Lactobacillaceae 91061|Bacilli K Transcriptional ydfF GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010035,GO:0010038,GO:0010288,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032791,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097063,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_20 AFLMLIMI_00831 543734.LCABL_04980 6.37e-259 712.0 COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,3F4X1@33958|Lactobacillaceae 91061|Bacilli EGP transporter yceJ - - ko:K08221 - - - - ko00000,ko02000 2.A.1.32 - - MFS_1,Sugar_tr AFLMLIMI_00832 543734.LCABL_04970 4.23e-64 195.0 COG0640@1|root,COG0640@2|Bacteria,1VAK2@1239|Firmicutes,4HMC7@91061|Bacilli,3F704@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain yczG - - - - - - - - - - - HTH_20,HTH_5 AFLMLIMI_00833 543734.LCABL_04960 0.0 931.0 29Q2U@1|root,30B1F@2|Bacteria,1U7DD@1239|Firmicutes,4IH99@91061|Bacilli,3F9F1@33958|Lactobacillaceae 91061|Bacilli L Exonuclease - - - - - - - - - - - - RNase_T AFLMLIMI_00834 543734.LCABL_04950 1.01e-99 289.0 COG1764@1|root,COG1764@2|Bacteria,1VY9T@1239|Firmicutes,4HXI7@91061|Bacilli,3F7CX@33958|Lactobacillaceae 91061|Bacilli O OsmC-like protein - - - - - - - - - - - - OsmC AFLMLIMI_00835 543734.LCABL_04940 1.03e-242 667.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli,3F4F2@33958|Lactobacillaceae 91061|Bacilli G Dak1 domain dhaK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 AFLMLIMI_00836 543734.LCABL_04930 2.01e-133 378.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli,3F5VS@33958|Lactobacillaceae 91061|Bacilli S Dak2 dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 AFLMLIMI_00837 543734.LCABL_04920 2.1e-78 233.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,4HKCN@91061|Bacilli,3F6YE@33958|Lactobacillaceae 91061|Bacilli S PTS system fructose IIA component dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 - - - EIIA-man AFLMLIMI_00838 543734.LCABL_04910 3.51e-131 372.0 COG1309@1|root,COG1309@2|Bacteria,1VCF7@1239|Firmicutes,4IQ66@91061|Bacilli,3FBG6@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_8,TetR_N AFLMLIMI_00839 543734.LCABL_04900 7.24e-23 87.4 29QJ1@1|root,30BIK@2|Bacteria,1U86E@1239|Firmicutes,4II3Y@91061|Bacilli,3FAKU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00840 543734.LCABL_04890 0.0 1139.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,4HAYH@91061|Bacilli,3F3QX@33958|Lactobacillaceae 91061|Bacilli S Myosin-crossreactive antigen l1n - 4.2.1.53 ko:K10254 - - - - ko00000,ko01000 - - - MCRA AFLMLIMI_00841 1423816.BACQ01000064_gene2468 4.99e-105 317.0 29Q1F@1|root,30B00@2|Bacteria,1U7BS@1239|Firmicutes,4IH72@91061|Bacilli,3F9AV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00842 543734.LCABL_04870 3.38e-252 691.0 COG3049@1|root,COG3049@2|Bacteria,1UZCV@1239|Firmicutes,4HFHU@91061|Bacilli,3FB8Y@33958|Lactobacillaceae 91061|Bacilli M Linear amide C-N hydrolases, choloylglycine hydrolase family - - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH AFLMLIMI_00843 543734.LCABL_04860 1.06e-198 551.0 COG1464@1|root,COG1464@2|Bacteria,1V0Z6@1239|Firmicutes,4HBBW@91061|Bacilli,3FC6K@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family metQ1 - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 AFLMLIMI_00844 568703.LGG_00476 0.0 875.0 COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,4HE6F@91061|Bacilli,3F5DP@33958|Lactobacillaceae 91061|Bacilli S Peptidase dimerisation domain - - - ko:K12941 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 AFLMLIMI_00845 568703.LGG_00475 2.26e-242 671.0 COG2271@1|root,COG2271@2|Bacteria,1UXYK@1239|Firmicutes,4HBU0@91061|Bacilli,3FCBT@33958|Lactobacillaceae 91061|Bacilli G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr AFLMLIMI_00846 568703.LGG_00474 0.0 981.0 COG2207@1|root,COG3664@1|root,COG2207@2|Bacteria,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,4HVRP@91061|Bacilli 91061|Bacilli GK helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - HTH_18 AFLMLIMI_00847 543734.LCABL_04840 0.0 1411.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein pip - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 AFLMLIMI_00849 543734.LCABL_04810 0.0 1044.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,3F63B@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_00850 1423816.BACQ01000064_gene2451 0.0 1073.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_00851 543734.LCABL_04780 0.0 1178.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.10 ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R01718,R01791,R06199 RC00028,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C AFLMLIMI_00852 543734.LCABL_04770 5.07e-89 261.0 COG2893@1|root,COG2893@2|Bacteria,1V7TP@1239|Firmicutes,4IQPD@91061|Bacilli,3F76S@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man AFLMLIMI_00853 543734.LCABL_04760 0.0 1534.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,3F4CE@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 31 family - - - - - - - - - - - - Glyco_hydro_31 AFLMLIMI_00854 543734.LCABL_04750 7.9e-196 544.0 COG3716@1|root,COG3716@2|Bacteria,1TSXA@1239|Firmicutes,4IQM2@91061|Bacilli,3FBHP@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA AFLMLIMI_00855 543734.LCABL_04740 2.18e-177 496.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_00856 543734.LCABL_04730 1.48e-109 315.0 COG3444@1|root,COG3444@2|Bacteria,1V8BP@1239|Firmicutes,4HWNX@91061|Bacilli,3F6R3@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb AFLMLIMI_00857 543734.LCABL_04720 1.15e-237 654.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 AFLMLIMI_00858 543734.LCABL_04710 4.27e-58 179.0 COG3041@1|root,COG3041@2|Bacteria,1U69Z@1239|Firmicutes,4IG17@91061|Bacilli,3F7EP@33958|Lactobacillaceae 91061|Bacilli S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - ko:K19157 - - - - ko00000,ko01000,ko02048 - - - YafQ_toxin AFLMLIMI_00859 543734.LCABL_04700 7.51e-194 538.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli,3F55S@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 AFLMLIMI_00860 543734.LCABL_04690 0.0 909.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase npr - 1.11.1.1 ko:K05910 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim AFLMLIMI_00861 543734.LCABL_04680 8.22e-85 249.0 COG4679@1|root,COG4679@2|Bacteria,1VHME@1239|Firmicutes,4IRT3@91061|Bacilli,3F7IG@33958|Lactobacillaceae 91061|Bacilli S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 AFLMLIMI_00862 543734.LCABL_04670 3.74e-53 167.0 COG1396@1|root,COG1396@2|Bacteria,1VMY1@1239|Firmicutes,4HRA4@91061|Bacilli,3F814@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AFLMLIMI_00863 543734.LCABL_04660 8.27e-153 430.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli,3F4RP@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00864 543734.LCABL_04650 4.67e-237 654.0 COG0577@1|root,COG0577@2|Bacteria,1TWFZ@1239|Firmicutes,4H9RQ@91061|Bacilli,3F3K5@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease yxeA - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD AFLMLIMI_00865 543734.LCABL_04640 5.12e-112 322.0 COG1309@1|root,COG1309@2|Bacteria,1V4D3@1239|Firmicutes,4HJ8Z@91061|Bacilli,3F6ZM@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AFLMLIMI_00866 543734.LCABL_12160 1.96e-36 140.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 AFLMLIMI_00867 543734.LCABL_04610 6.36e-173 483.0 COG3757@1|root,COG3757@2|Bacteria,1V3SH@1239|Firmicutes,4HNR1@91061|Bacilli,3F6ZF@33958|Lactobacillaceae 91061|Bacilli M hydrolase, family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 AFLMLIMI_00868 568703.LGG_00485 7.72e-17 72.8 29QPW@1|root,30BPK@2|Bacteria,1U8F6@1239|Firmicutes,4IID2@91061|Bacilli,3FAX1@33958|Lactobacillaceae 91061|Bacilli S YvrJ protein family - - - - - - - - - - - - YvrJ AFLMLIMI_00870 543734.LCABL_04580 9.19e-304 828.0 COG0477@1|root,COG0477@2|Bacteria,1TQIJ@1239|Firmicutes,4HAM0@91061|Bacilli,3F3N4@33958|Lactobacillaceae 91061|Bacilli EGP Sugar (and other) transporter proP - - ko:K03761,ko:K03762 - - - - ko00000,ko02000 2.A.1.6.2,2.A.1.6.4 - - MFS_1,Sugar_tr AFLMLIMI_00871 1423815.BACR01000037_gene1783 1.91e-70 220.0 COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,4HN5N@91061|Bacilli,3F6YM@33958|Lactobacillaceae 91061|Bacilli C nitroreductase - - - - - - - - - - - - Nitroreductase AFLMLIMI_00872 387344.LVIS_0746 1.86e-17 79.0 COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HH0A@91061|Bacilli,3F7S1@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family ydeP - - - - - - - - - - - HxlR AFLMLIMI_00873 1158607.UAU_01360 7.66e-191 540.0 COG0246@1|root,COG0246@2|Bacteria,1TS6C@1239|Firmicutes,4HTKF@91061|Bacilli,4B1E9@81852|Enterococcaceae 91061|Bacilli G Mannitol dehydrogenase C-terminal domain - - 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh_C AFLMLIMI_00874 1158607.UAU_01359 1.05e-299 836.0 COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,4HUCH@91061|Bacilli,4B1JC@81852|Enterococcaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.197 ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB AFLMLIMI_00875 1545702.LACWKB8_0173 1.58e-146 417.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F9T3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short AFLMLIMI_00876 1545702.LACWKB8_0174 1.33e-77 242.0 COG1349@1|root,COG1349@2|Bacteria,1UYMW@1239|Firmicutes,4HBQ1@91061|Bacilli,3FC5W@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR AFLMLIMI_00877 543734.LCABL_04500 6.72e-125 356.0 COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,4HE2U@91061|Bacilli,3FB4E@33958|Lactobacillaceae 91061|Bacilli M SIS domain - - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS AFLMLIMI_00878 543734.LCABL_04490 5.04e-147 414.0 COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,3F54B@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family - - 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AFLMLIMI_00879 543734.LCABL_04480 1.95e-172 482.0 COG1349@1|root,COG1349@2|Bacteria,1UXJ3@1239|Firmicutes,4I2XW@91061|Bacilli,3F89K@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AFLMLIMI_00880 543734.LCABL_04470 3.04e-155 436.0 COG0637@1|root,COG0637@2|Bacteria,1V1N8@1239|Firmicutes,4HG58@91061|Bacilli,3F56K@33958|Lactobacillaceae 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 AFLMLIMI_00882 1423806.JCM15457_625 0.0 932.0 COG1621@1|root,COG3386@1|root,COG1621@2|Bacteria,COG3386@2|Bacteria,1UX3T@1239|Firmicutes,4I2IG@91061|Bacilli,3F8QB@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 32 - - 3.2.1.65 ko:K01212 ko00500,map00500 - R05624,R11311 RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N AFLMLIMI_00883 913848.AELK01000047_gene2613 9.35e-74 221.0 2EC9R@1|root,33683@2|Bacteria,1VIEC@1239|Firmicutes,4HSN3@91061|Bacilli,3F7A0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00884 543734.LCABL_04440 2.15e-199 552.0 COG3716@1|root,COG3716@2|Bacteria,1UNST@1239|Firmicutes,4HEX7@91061|Bacilli,3F5DT@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component levD - - ko:K02771 ko00051,ko02060,map00051,map02060 M00304 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.2 - - EIID-AGA AFLMLIMI_00885 543734.LCABL_04430 5.53e-196 547.0 COG3715@1|root,COG3715@2|Bacteria,1U8TN@1239|Firmicutes,4HE9V@91061|Bacilli,3F4QF@33958|Lactobacillaceae 91061|Bacilli M PTS system sorbose-specific iic component levC - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_00886 543734.LCABL_04420 2.66e-117 335.0 COG3444@1|root,COG3444@2|Bacteria,1UZRR@1239|Firmicutes,4HV38@91061|Bacilli,3FCCV@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb AFLMLIMI_00887 543734.LCABL_04410 2.77e-94 275.0 COG2893@1|root,COG2893@2|Bacteria,1VBC1@1239|Firmicutes,4IQPC@91061|Bacilli,3F6SH@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - - ko:K02744 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4,4.A.6.1.5 - - EIIA-man AFLMLIMI_00888 543734.LCABL_04400 0.0 1632.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,3F3N6@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 interaction domain - - - - - - - - - - - - EIIA-man,PRD,Sigma54_activ_2,Sigma54_activat AFLMLIMI_00889 1423816.BACQ01000063_gene2426 1.85e-27 107.0 COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,4ISD2@91061|Bacilli,3F53H@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC AFLMLIMI_00890 543734.LCABL_04370 3.27e-191 531.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli,3F3Y9@33958|Lactobacillaceae 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ AFLMLIMI_00891 543734.LCABL_04360 0.0 1097.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3F4XP@33958|Lactobacillaceae 91061|Bacilli P ABC transporter, ATP-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 AFLMLIMI_00892 543734.LCABL_04350 1.05e-127 363.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli,3F5A7@33958|Lactobacillaceae 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS AFLMLIMI_00893 543734.LCABL_04330 4.54e-205 566.0 COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli,3F3JD@33958|Lactobacillaceae 91061|Bacilli K S-adenosyl-l-methionine hydroxide adenosyltransferase XK27_10120 - - - - - - - - - - - SAM_adeno_trans AFLMLIMI_00894 543734.LCABL_04320 8.42e-204 565.0 COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,4HFSV@91061|Bacilli,3F48I@33958|Lactobacillaceae 1239|Firmicutes K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_00895 543734.LCABL_04310 3.72e-300 819.0 COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,4HBWH@91061|Bacilli 91061|Bacilli C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored AFLMLIMI_00896 543734.LCABL_04300 5.86e-110 329.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli 91061|Bacilli P transporter sdcS GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp AFLMLIMI_00897 543734.LCABL_04300 2.04e-203 572.0 COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli 91061|Bacilli P transporter sdcS GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656 - ko:K14445 - - - - ko00000,ko02000 2.A.47.1 - - Na_sulph_symp AFLMLIMI_00898 543734.LCABL_04290 3.33e-211 583.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HGMN@91061|Bacilli,3FCBA@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II kbaY - 4.1.2.13,4.1.2.40 ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01069,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase AFLMLIMI_00899 543734.LCABL_04280 8.69e-195 541.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manZ - - ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00278 R02630,R04076 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3 - - EIID-AGA AFLMLIMI_00900 543734.LCABL_04270 3.93e-184 513.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F5QK@33958|Lactobacillaceae 91061|Bacilli U PTS system sorbose-specific iic component - - - ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00278 R02630,R04076,R08366 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3,4.A.6.1.4 - - EII-Sor AFLMLIMI_00901 543734.LCABL_04260 4.08e-112 322.0 COG3444@1|root,COG3444@2|Bacteria,1V3X7@1239|Firmicutes,4HH17@91061|Bacilli,3F6T0@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.206 ko:K02813 ko00051,ko02060,map00051,map02060 M00278 R04076 RC01069,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.3 - - PTSIIB_sorb AFLMLIMI_00902 543734.LCABL_04250 1.24e-89 263.0 COG2893@1|root,COG2893@2|Bacteria,1VGQT@1239|Firmicutes,4HNXM@91061|Bacilli,3F7YA@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.206 ko:K02812 ko00051,ko02060,map00051,map02060 M00278 R04076 RC01069,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.3 - - EIIA-man AFLMLIMI_00903 543734.LCABL_04240 5.02e-186 517.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD2 - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short AFLMLIMI_00904 543734.LCABL_04230 3.25e-224 618.0 COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,4HCAR@91061|Bacilli,3F4PP@33958|Lactobacillaceae 91061|Bacilli K sugar-binding domain protein - - - - - - - - - - - - Sugar-bind AFLMLIMI_00905 543734.LCABL_04220 4.08e-311 846.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,4HBV4@91061|Bacilli,3F602@33958|Lactobacillaceae 91061|Bacilli E Alcohol dehydrogenase GroES-like domain - - - ko:K19956 ko00051,map00051 - R03234 RC00089 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N AFLMLIMI_00906 543734.LCABL_04210 5.41e-171 478.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4I39G@91061|Bacilli,3FA85@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_00907 543734.LCABL_04200 1.07e-84 252.0 COG0794@1|root,COG0794@2|Bacteria,1V3UJ@1239|Firmicutes,4HH5G@91061|Bacilli,3F7I2@33958|Lactobacillaceae 91061|Bacilli M sugar phosphate isomerase involved in capsule formation hxlB - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS AFLMLIMI_00908 543734.LCABL_04190 5.39e-152 427.0 COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,3F54B@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family hxlA GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AFLMLIMI_00909 543734.LCABL_04180 7.21e-237 652.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4HU2R@91061|Bacilli,3F9K8@33958|Lactobacillaceae 91061|Bacilli G Dak1 domain - - 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 AFLMLIMI_00910 543734.LCABL_04170 2.12e-146 413.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli,3FA2V@33958|Lactobacillaceae 91061|Bacilli S Dak2 dhaL - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Dak2 AFLMLIMI_00911 543734.LCABL_04160 1.5e-278 762.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,3F448@33958|Lactobacillaceae 91061|Bacilli C mannitol-1-phosphate 5-dehydrogenase activity mtlD - 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C AFLMLIMI_00912 543734.LCABL_04150 5.44e-198 550.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component - - - ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 M00276,M00610 R02630,R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17 - - EIID-AGA AFLMLIMI_00913 543734.LCABL_04140 5.6e-170 475.0 COG3715@1|root,COG3715@2|Bacteria,1V07Y@1239|Firmicutes,4IQM7@91061|Bacilli 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K17466 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1.17 - - EII-Sor AFLMLIMI_00914 543734.LCABL_04130 5.98e-111 319.0 COG3444@1|root,COG3444@2|Bacteria,1V92Y@1239|Firmicutes,4HXTT@91061|Bacilli 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.203 ko:K17465 ko00030,ko01120,ko02060,map00030,map01120,map02060 M00610 R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.17 - - PTSIIB_sorb AFLMLIMI_00915 543734.LCABL_04120 1.33e-44 147.0 COG2893@1|root,COG2893@2|Bacteria,1VCQI@1239|Firmicutes,4I36M@91061|Bacilli,3F6W9@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191,2.7.1.203 ko:K02793,ko:K17464 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 M00276,M00610 R02630,R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1,4.A.6.1.17 - - EIIA-man AFLMLIMI_00916 543734.LCABL_04110 1.5e-187 521.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F9T3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short AFLMLIMI_00917 543734.LCABL_04070 0.0 1236.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F9FH@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system - - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB AFLMLIMI_00918 543734.LCABL_04060 8.51e-204 564.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HD42@91061|Bacilli,3F58Z@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase AFLMLIMI_00919 543734.LCABL_04050 0.0 1206.0 COG3711@1|root,COG3711@2|Bacteria,1TQTV@1239|Firmicutes,4HFDM@91061|Bacilli 91061|Bacilli K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - HTH_11,PRD,PTS_EIIA_2 AFLMLIMI_00920 543734.LCABL_04040 0.0 1102.0 2DX0A@1|root,342SP@2|Bacteria,1UIXQ@1239|Firmicutes,4ISW1@91061|Bacilli,3F9EI@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - - - - - - - - - - HTH_11,PTS_EIIA_2 AFLMLIMI_00921 543734.LCABL_04030 6.35e-290 791.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F5DH@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase class I and II malY - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_00922 543734.LCABL_04020 0.0 982.0 COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1TPKU@1239|Firmicutes,4HD9N@91061|Bacilli,3FCBF@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit pts31BC - - ko:K11202,ko:K11203 - M00306 - - ko00000,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIC,PTS_IIB AFLMLIMI_00923 543734.LCABL_04010 3.87e-24 94.0 COG1762@1|root,COG1762@2|Bacteria,1VDC4@1239|Firmicutes,4HNDE@91061|Bacilli,3FCBG@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K11201 - M00306 - - ko00000,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 AFLMLIMI_00924 543734.LCABL_04010 2.15e-45 150.0 COG1762@1|root,COG1762@2|Bacteria,1VDC4@1239|Firmicutes,4HNDE@91061|Bacilli,3FCBG@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K11201 - M00306 - - ko00000,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 AFLMLIMI_00925 543734.LCABL_03990 0.0 972.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family xylB - 2.7.1.17,2.7.1.53 ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 M00014 R01639,R01901,R07127 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N AFLMLIMI_00926 543734.LCABL_03980 1.4e-173 483.0 COG3822@1|root,COG3822@2|Bacteria,1UXBF@1239|Firmicutes,4HVN6@91061|Bacilli,3F9JP@33958|Lactobacillaceae 91061|Bacilli S Pfam:DUF1498 - - 5.3.1.15 ko:K09988 ko00040,map00040 - R01898 RC00516 ko00000,ko00001,ko01000 - - - Lyx_isomer AFLMLIMI_00927 543734.LCABL_03970 1.44e-230 635.0 COG2017@1|root,COG2017@2|Bacteria,1V5SP@1239|Firmicutes,4IRIW@91061|Bacilli,3F96V@33958|Lactobacillaceae 91061|Bacilli G Domain of unknown function (DUF4432) - - - - - - - - - - - - DUF4432 AFLMLIMI_00928 543734.LCABL_03960 2.35e-218 607.0 COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,4H9XS@91061|Bacilli,3F52Q@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase System - - - ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.2.1 - - PTS_EIIC AFLMLIMI_00929 543734.LCABL_03950 1.08e-63 195.0 COG1445@1|root,COG1445@2|Bacteria,1VASC@1239|Firmicutes,4HKYF@91061|Bacilli,3F7K8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.202 ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_IIB AFLMLIMI_00930 543734.LCABL_03940 8.68e-106 305.0 COG1762@1|root,COG1762@2|Bacteria,1V5TG@1239|Firmicutes,4HND7@91061|Bacilli,3F7H8@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 AFLMLIMI_00931 543734.LCABL_03930 7.37e-223 614.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HD42@91061|Bacilli,3F58Z@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase AFLMLIMI_00932 543734.LCABL_03920 3.15e-103 299.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system ptsN GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 - - PTS_EIIA_2 AFLMLIMI_00933 543734.LCABL_03910 0.0 932.0 COG3711@1|root,COG3711@2|Bacteria,1TSGM@1239|Firmicutes,4HB3W@91061|Bacilli,3F482@33958|Lactobacillaceae 91061|Bacilli K PRD domain - - - ko:K02538 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB AFLMLIMI_00934 543734.LCABL_03900 2.23e-302 826.0 COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,4HA8T@91061|Bacilli,3F4R8@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 factor, core binding domain rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD AFLMLIMI_00935 543734.LCABL_03890 0.0 1763.0 COG1221@1|root,COG3933@1|root,COG1221@2|Bacteria,COG3933@2|Bacteria,1VSHE@1239|Firmicutes,4HB6T@91061|Bacilli,3F3N6@33958|Lactobacillaceae 91061|Bacilli K Sigma-54 interaction domain - - - ko:K19505 - - - - ko00000,ko03000 - - - EIIA-man,PRD,Sigma54_activat AFLMLIMI_00936 543734.LCABL_03880 8.5e-91 266.0 COG2893@1|root,COG2893@2|Bacteria,1VCJ2@1239|Firmicutes,4HPXK@91061|Bacilli,3F7TA@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man AFLMLIMI_00937 543734.LCABL_03870 1.12e-116 334.0 COG3444@1|root,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,3F4PU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb AFLMLIMI_00938 543734.LCABL_03860 3.94e-173 484.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3FBHQ@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_00939 543734.LCABL_03850 1.23e-193 538.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component - - - ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 M00276,M00610 R02630,R10407 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.17 - - EIID-AGA AFLMLIMI_00940 543734.LCABL_03840 1.78e-195 541.0 COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli,3FCD2@33958|Lactobacillaceae 91061|Bacilli S Putative esterase estA - - ko:K03930 - - - - ko00000,ko01000 - CE1 - Esterase AFLMLIMI_00941 543734.LCABL_03790 2.25e-236 652.0 COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4HEMS@91061|Bacilli,3F89R@33958|Lactobacillaceae 91061|Bacilli C Iron-sulfur cluster-binding domain ydeM3 - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM AFLMLIMI_00942 543734.LCABL_03780 4.92e-169 474.0 COG0730@1|root,COG0730@2|Bacteria,1UY5F@1239|Firmicutes,4HEQF@91061|Bacilli,3F7B6@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE AFLMLIMI_00943 543734.LCABL_03770 1.89e-205 567.0 COG1262@1|root,COG1262@2|Bacteria,1TT4R@1239|Firmicutes,4HA8D@91061|Bacilli 91061|Bacilli S Sulfatase-modifying factor enzyme 1 pkn1 - - - - - - - - - - - DinB_2,FGE-sulfatase AFLMLIMI_00944 1154860.SAG0136_07715 2.7e-283 782.0 COG3119@1|root,COG3119@2|Bacteria,1TSHE@1239|Firmicutes,4IQVE@91061|Bacilli 91061|Bacilli P Type I phosphodiesterase / nucleotide pyrophosphatase - - - - - - - - - - - - DUF4976,Sulfatase AFLMLIMI_00945 543734.LCABL_03710 4.97e-166 466.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HCQB@91061|Bacilli,3FBHN@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA AFLMLIMI_00946 543734.LCABL_03700 1.22e-181 507.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4HFQS@91061|Bacilli,3FC9E@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_00947 543734.LCABL_03690 7.42e-230 633.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator msmR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AFLMLIMI_00948 543734.LCABL_03670 3.67e-109 317.0 2EM6V@1|root,33EW2@2|Bacteria,1VNUQ@1239|Firmicutes,4HRSG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00949 543734.LCABL_03660 1.61e-192 536.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HFV8@91061|Bacilli 91061|Bacilli V Beta-lactamase bla1 - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2,zinc_ribbon_2 AFLMLIMI_00950 1291743.LOSG293_590030 5.11e-93 270.0 2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli,3F6WW@33958|Lactobacillaceae 91061|Bacilli S Pyrimidine dimer DNA glycosylase yqeB - - - - - - - - - - - Pyr_excise AFLMLIMI_00951 543734.LCABL_03610 9.65e-91 265.0 COG3576@1|root,COG3576@2|Bacteria,1VW4G@1239|Firmicutes,4HW37@91061|Bacilli,3F6IW@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx AFLMLIMI_00952 543734.LCABL_03600 9.02e-291 831.0 COG3209@1|root,COG3209@2|Bacteria,1TT3P@1239|Firmicutes,4I28K@91061|Bacilli,3F4YY@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF5011) - - - - - - - - - - - - Big_3,DUF285,Gram_pos_anchor AFLMLIMI_00954 543734.LCABL_03550 2.72e-191 530.0 COG0596@1|root,COG0596@2|Bacteria,1UKJS@1239|Firmicutes,4ITJ3@91061|Bacilli 91061|Bacilli S Alpha/beta hydrolase family - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 AFLMLIMI_00955 543734.LCABL_03540 1.68e-228 630.0 COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,4HBWI@91061|Bacilli,3F5HH@33958|Lactobacillaceae 91061|Bacilli E Ornithine cyclodeaminase/mu-crystallin family - - 4.3.1.12 ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 - R00671 RC00354 ko00000,ko00001,ko01000 - - - OCD_Mu_crystall AFLMLIMI_00956 543734.LCABL_03530 9.64e-191 531.0 COG0730@1|root,COG0730@2|Bacteria,1TQ8H@1239|Firmicutes,4IIWZ@91061|Bacilli,3F7J9@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE AFLMLIMI_00957 543734.LCABL_03520 3.2e-203 561.0 COG1378@1|root,COG1378@2|Bacteria,1TTRR@1239|Firmicutes,4IHFC@91061|Bacilli,3F9RY@33958|Lactobacillaceae 91061|Bacilli K Sugar-specific transcriptional regulator TrmB - - - - - - - - - - - - TrmB AFLMLIMI_00958 543734.LCABL_03510 7.78e-150 421.0 COG0645@1|root,COG0645@2|Bacteria,1V4KB@1239|Firmicutes,4HI0A@91061|Bacilli,3F7CA@33958|Lactobacillaceae 91061|Bacilli S Zeta toxin - - - - - - - - - - - - AAA_33,Zeta_toxin AFLMLIMI_00959 543734.LCABL_03500 6.47e-208 574.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4HA99@91061|Bacilli,3F611@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II - - 4.1.2.13 ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase AFLMLIMI_00960 543734.LCABL_03490 5.04e-90 264.0 2DQQD@1|root,32UPI@2|Bacteria,1VIC6@1239|Firmicutes,4HSMN@91061|Bacilli,3F8E7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - TPR_1 AFLMLIMI_00961 543734.LCABL_03480 5.62e-292 799.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT AFLMLIMI_00962 543734.LCABL_03470 3.38e-66 201.0 COG3414@1|root,COG3414@2|Bacteria,1VBHM@1239|Firmicutes,4HM7H@91061|Bacilli,3F96C@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB AFLMLIMI_00963 543734.LCABL_03450 4.69e-250 702.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,3F64K@33958|Lactobacillaceae 91061|Bacilli GKT transcriptional antiterminator - - - - - - - - - - - - HTH_11,Mga,PRD,PTS_EIIA_2 AFLMLIMI_00964 543734.LCABL_03440 0.0 951.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4ISAE@91061|Bacilli,3FBRV@33958|Lactobacillaceae 91061|Bacilli C HI0933-like protein frdC - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C AFLMLIMI_00965 543734.LCABL_03420 3.9e-172 482.0 2AIFZ@1|root,33KBF@2|Bacteria,1UPZ6@1239|Firmicutes,4IVDJ@91061|Bacilli,3F6BW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00966 543734.LCABL_03410 8.53e-139 394.0 29QRY@1|root,30BRT@2|Bacteria,1U8J4@1239|Firmicutes,4IIH3@91061|Bacilli,3FB1I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00967 543734.LCABL_03400 9.65e-163 456.0 29P41@1|root,30A28@2|Bacteria,1U63C@1239|Firmicutes,4IFSS@91061|Bacilli,3F6Y1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00968 1423732.BALS01000032_gene234 1.25e-113 330.0 COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,4I2PJ@91061|Bacilli,3F4H6@33958|Lactobacillaceae 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_00969 543734.LCABL_03360 1.29e-122 349.0 29P6Z@1|root,30A52@2|Bacteria,1U67I@1239|Firmicutes,4IFY3@91061|Bacilli,3F796@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00970 543734.LCABL_03350 7.42e-89 260.0 28ZBI@1|root,2ZM3D@2|Bacteria,1W5K5@1239|Firmicutes,4I1Q6@91061|Bacilli,3F825@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 AFLMLIMI_00971 543734.LCABL_03340 5.44e-83 251.0 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00972 543734.LCABL_03330 1.84e-81 246.0 29QQ0@1|root,30BPR@2|Bacteria,1U8FC@1239|Firmicutes,4IID8@91061|Bacilli,3FAX8@33958|Lactobacillaceae 543734.LCABL_03330|- - - - - - - - - - - - - - - - AFLMLIMI_00973 543734.LCABL_03320 4.22e-41 135.0 2ATAB@1|root,31ITC@2|Bacteria,1U735@1239|Firmicutes,4IGXP@91061|Bacilli,3F8WX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00974 543734.LCABL_03310 2.06e-129 367.0 2DEN3@1|root,32U3P@2|Bacteria,1VXXQ@1239|Firmicutes,4HXNG@91061|Bacilli,3F73U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00975 543734.LCABL_03300 2.2e-95 278.0 COG1846@1|root,COG1846@2|Bacteria,1V939@1239|Firmicutes,4HJRC@91061|Bacilli,3F7MR@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR AFLMLIMI_00976 543734.LCABL_03290 1.31e-304 833.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F4D4@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1,MFS_3 AFLMLIMI_00977 543734.LCABL_03280 0.0 1289.0 COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,4IQSR@91061|Bacilli,3F5K3@33958|Lactobacillaceae 91061|Bacilli M NTF2-like N-terminal transpeptidase domain pbpC - - ko:K21467 - - - - ko00000,ko01011 - - - MecA_N,PBP_dimer,Transpeptidase AFLMLIMI_00978 543734.LCABL_03270 7.53e-54 168.0 COG2161@1|root,COG2161@2|Bacteria,1VAJF@1239|Firmicutes,4HPRS@91061|Bacilli,3F7SP@33958|Lactobacillaceae 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module - - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox AFLMLIMI_00979 543734.LCABL_03260 7.76e-207 573.0 COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,4HE6Z@91061|Bacilli,3FB6B@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB AFLMLIMI_00980 543734.LCABL_03250 1.41e-214 594.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,3FCEY@33958|Lactobacillaceae 91061|Bacilli G Periplasmic binding protein domain rbsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 AFLMLIMI_00981 543734.LCABL_03240 4.84e-198 553.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,3F5NF@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 AFLMLIMI_00982 543734.LCABL_03230 0.0 972.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,3FBUB@33958|Lactobacillaceae 91061|Bacilli G ABC transporter rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran AFLMLIMI_00983 543734.LCABL_03220 2.2e-86 254.0 COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,3F6GA@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD - 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU AFLMLIMI_00984 543734.LCABL_03210 2.08e-240 660.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4HE07@91061|Bacilli,3F44Q@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family rbsR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AFLMLIMI_00985 543734.LCABL_03200 1.16e-45 147.0 2AIT2@1|root,3199Z@2|Bacteria,1U879@1239|Firmicutes,4II4Z@91061|Bacilli,3FAMW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_00986 543734.LCABL_03180 0.0 937.0 COG0531@1|root,COG0531@2|Bacteria,1UYSD@1239|Firmicutes,4IPMN@91061|Bacilli,3F48U@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease - - - - - - - - - - - - AA_permease_2 AFLMLIMI_00987 543734.LCABL_03170 6.07e-187 520.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,3F3NA@33958|Lactobacillaceae 91061|Bacilli H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin AFLMLIMI_00988 543734.LCABL_03160 6.07e-138 391.0 COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,3FB7Y@33958|Lactobacillaceae 91061|Bacilli H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI AFLMLIMI_00989 543734.LCABL_03150 1.18e-191 533.0 COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,4HFTJ@91061|Bacilli,3F43J@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK AFLMLIMI_00990 543734.LCABL_03140 5.11e-107 309.0 COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,4HHG6@91061|Bacilli,3F6M6@33958|Lactobacillaceae 91061|Bacilli S Thiamine-precursor transporter protein (ThiW) thiW - - - - - - - - - - - ThiW AFLMLIMI_00991 543734.LCABL_03130 1.39e-165 462.0 COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,4HCPF@91061|Bacilli,3FB7U@33958|Lactobacillaceae 91061|Bacilli K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway tenA - 3.5.99.2 ko:K03707 ko00730,ko01100,map00730,map01100 - R02133,R09993 RC00224,RC00652,RC02832 ko00000,ko00001,ko01000,ko03000 - - - TENA_THI-4 AFLMLIMI_00992 543734.LCABL_03120 1.55e-141 400.0 COG0619@1|root,COG0619@2|Bacteria,1TUDZ@1239|Firmicutes,4HCPC@91061|Bacilli,3F4FG@33958|Lactobacillaceae 91061|Bacilli P cobalt transport ykoC - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ AFLMLIMI_00993 543734.LCABL_03110 4.66e-312 851.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli,3FBS0@33958|Lactobacillaceae 91061|Bacilli P ABC transporter - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran AFLMLIMI_00994 543734.LCABL_03100 8.84e-121 346.0 COG4721@1|root,COG4721@2|Bacteria,1V2G5@1239|Firmicutes,4IRFG@91061|Bacilli,3FBNZ@33958|Lactobacillaceae 91061|Bacilli S ABC-type cobalt transport system, permease component - - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt AFLMLIMI_00997 543734.LCABL_03080 3.58e-155 435.0 COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,4HGZK@91061|Bacilli,3F7G3@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) family - - - ko:K03824 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_9 AFLMLIMI_00998 543734.LCABL_03070 0.0 1052.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AFLMLIMI_00999 543734.LCABL_03060 2.45e-309 842.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,3F45V@33958|Lactobacillaceae 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 AFLMLIMI_01000 543734.LCABL_03050 0.0 1160.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TS2U@1239|Firmicutes,4HTK5@91061|Bacilli,3F6RZ@33958|Lactobacillaceae 91061|Bacilli GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,PRD,PTS_EIIA_2 AFLMLIMI_01001 543734.LCABL_03040 2.86e-240 661.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli,3F55I@33958|Lactobacillaceae 91061|Bacilli E M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 AFLMLIMI_01002 543734.LCABL_03030 3.39e-67 204.0 COG1447@1|root,COG1447@2|Bacteria,1VCDD@1239|Firmicutes,4HZCJ@91061|Bacilli,3F7P9@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA AFLMLIMI_01003 543734.LCABL_03020 2.96e-78 232.0 COG1440@1|root,COG1440@2|Bacteria,1V6UA@1239|Firmicutes,4HK0J@91061|Bacilli,3F8G8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB AFLMLIMI_01004 543734.LCABL_03010 0.0 870.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HEGS@91061|Bacilli,3F744@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_01005 543734.LCABL_03000 9.63e-246 676.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HV4S@91061|Bacilli,3F9GC@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 AFLMLIMI_01006 1423816.BACQ01000062_gene2361 5.29e-243 673.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,3F4JX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase, class I patB - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_01007 543734.LCABL_02960 2.65e-287 786.0 2E865@1|root,332JJ@2|Bacteria,1VJ1K@1239|Firmicutes,4IFBU@91061|Bacilli,3F662@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2325) - - - - - - - - - - - - DUF2325 AFLMLIMI_01008 543734.LCABL_02950 2.72e-85 251.0 COG2893@1|root,COG2893@2|Bacteria,1VB8U@1239|Firmicutes,4HKV5@91061|Bacilli,3F7YU@33958|Lactobacillaceae 91061|Bacilli G PTS system fructose IIA component - - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man AFLMLIMI_01009 543734.LCABL_02940 3.66e-187 521.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HC75@91061|Bacilli,3F434@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA AFLMLIMI_01010 543734.LCABL_02930 4.68e-206 571.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_01011 543734.LCABL_02920 5.61e-108 311.0 COG3444@1|root,COG3444@2|Bacteria,1V46G@1239|Firmicutes,4HHPN@91061|Bacilli,3FC7S@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb AFLMLIMI_01012 543734.LCABL_02910 0.0 1246.0 COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,4HBAR@91061|Bacilli,3F5XU@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 35 bgaC - 3.2.1.23 ko:K12308 ko00052,map00052 - R01105 RC00452 ko00000,ko00001,ko01000 - - - BetaGal_dom4_5,Glyco_hydro_35 AFLMLIMI_01013 543734.LCABL_02900 1.25e-285 779.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 AFLMLIMI_01014 543734.LCABL_02890 2.82e-281 769.0 COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,4HDKQ@91061|Bacilli,3F3YS@33958|Lactobacillaceae 91061|Bacilli G SIS domain agaS - - ko:K02082 - - - - ko00000,ko01000 - - - SIS AFLMLIMI_01015 543734.LCABL_02880 5.43e-167 467.0 COG2188@1|root,COG2188@2|Bacteria,1UYYY@1239|Firmicutes,4HGI6@91061|Bacilli,3F5F4@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_01016 543734.LCABL_02870 9.12e-249 681.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli,3F40I@33958|Lactobacillaceae 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI AFLMLIMI_01017 543734.LCABL_02860 0.0 1093.0 COG3525@1|root,COG3525@2|Bacteria,1TT9S@1239|Firmicutes,4HEM6@91061|Bacilli 91061|Bacilli G Gram-positive signal peptide protein, YSIRK family strH - 3.2.1.52 ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 M00079 R00022,R06004,R11316 RC00049 ko00000,ko00001,ko00002,ko01000,ko03110 - GH20 - G5,Glyco_hydro_20,Gram_pos_anchor,YSIRK_signal AFLMLIMI_01018 543734.LCABL_02850 9.04e-110 321.0 29V33@1|root,30GGE@2|Bacteria,1UFZH@1239|Firmicutes,4IF1H@91061|Bacilli,3F5BQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01019 543734.LCABL_02840 3.49e-307 837.0 COG1653@1|root,COG1653@2|Bacteria,1TSBD@1239|Firmicutes,4IQ65@91061|Bacilli,3F5HX@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 AFLMLIMI_01020 543734.LCABL_02830 0.0 1572.0 COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,3F473@33958|Lactobacillaceae 91061|Bacilli KL DEAD_2 uvrB3 - 3.1.12.1 ko:K07464 - - - - ko00000,ko01000,ko02048 - - - DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1 AFLMLIMI_01021 543734.LCABL_02820 1.18e-155 437.0 2EEPZ@1|root,338HP@2|Bacteria,1VJZJ@1239|Firmicutes,4HR6K@91061|Bacilli,3F55G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01022 543734.LCABL_02810 4.89e-201 556.0 28MN3@1|root,2ZAXQ@2|Bacteria,1US2T@1239|Firmicutes,4HW4H@91061|Bacilli,3F55K@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01023 543734.LCABL_02800 0.0 892.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim AFLMLIMI_01026 543734.LCABL_02770 8.47e-204 581.0 COG0791@1|root,COG0791@2|Bacteria,1VG0Z@1239|Firmicutes,4HBE9@91061|Bacilli,3F50V@33958|Lactobacillaceae 91061|Bacilli M NlpC P60 family protein p75 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,SLAP AFLMLIMI_01027 543734.LCABL_02760 3.82e-167 467.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli,3F4K1@33958|Lactobacillaceae 91061|Bacilli F Purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 AFLMLIMI_01028 543734.LCABL_02750 3.24e-293 799.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli,3F3Y4@33958|Lactobacillaceae 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008973,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0034641,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme AFLMLIMI_01029 543734.LCABL_02740 8.32e-149 419.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC,NUDIX AFLMLIMI_01030 543734.LCABL_02720 4.1e-152 428.0 COG3010@1|root,COG3010@2|Bacteria,1VTI6@1239|Firmicutes,4HV5Q@91061|Bacilli,3F3YB@33958|Lactobacillaceae 91061|Bacilli G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) - - - - - - - - - - - - - AFLMLIMI_01031 543734.LCABL_02710 1.59e-303 829.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HE28@91061|Bacilli,3FC6Y@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane pts14C - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_01032 543734.LCABL_02700 7.59e-214 590.0 COG4814@1|root,COG4814@2|Bacteria,1V8NG@1239|Firmicutes,4HJ22@91061|Bacilli,3F41V@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 AFLMLIMI_01033 543734.LCABL_02690 1.16e-159 448.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,3F3RP@33958|Lactobacillaceae 91061|Bacilli E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran AFLMLIMI_01034 543734.LCABL_02680 1.74e-179 500.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli,3F4IH@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid ATP-binding cassette transporter livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C AFLMLIMI_01035 543734.LCABL_02670 1.1e-182 513.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,3F44M@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid transport system / permease component livM - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 AFLMLIMI_01036 543734.LCABL_02660 1.04e-191 534.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,3F56V@33958|Lactobacillaceae 91061|Bacilli U Branched-chain amino acid transport system / permease component livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 AFLMLIMI_01037 543734.LCABL_02650 1.61e-273 749.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,3F591@33958|Lactobacillaceae 91061|Bacilli E Receptor family ligand binding region livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 AFLMLIMI_01038 543734.LCABL_02640 2.51e-98 286.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F63I@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 AFLMLIMI_01039 543734.LCABL_02630 8.95e-176 491.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE AFLMLIMI_01040 543734.LCABL_02620 3.02e-71 214.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,3F7I4@33958|Lactobacillaceae 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin AFLMLIMI_01042 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - AFLMLIMI_01043 568703.LGG_00302 1.45e-46 149.0 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,3F8E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01044 543734.LCABL_02570 5.64e-173 483.0 COG0500@1|root,COG0500@2|Bacteria,1VDQJ@1239|Firmicutes,4IT3M@91061|Bacilli,3F8EP@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase domain ypaC - - - - - - - - - - - Methyltransf_25 AFLMLIMI_01045 543734.LCABL_02560 0.0 1010.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,3FC7X@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - - - - - - - - - - ABC_tran,ABC_tran_Xtn AFLMLIMI_01046 543734.LCABL_02550 4.8e-223 615.0 COG1397@1|root,COG1397@2|Bacteria,1TQXG@1239|Firmicutes,4HE5F@91061|Bacilli,3F509@33958|Lactobacillaceae 91061|Bacilli O ADP-ribosylglycohydrolase draG - - - - - - - - - - - ADP_ribosyl_GH AFLMLIMI_01047 543734.LCABL_02540 1.26e-139 394.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,3F4SM@33958|Lactobacillaceae 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 AFLMLIMI_01048 1423732.BALS01000075_gene2102 4.42e-54 171.0 29PTZ@1|root,30AS5@2|Bacteria,1U71D@1239|Firmicutes,4IGVU@91061|Bacilli,3F8UT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01049 543734.LCABL_02510 1.8e-173 484.0 COG5523@1|root,COG5523@2|Bacteria,1U7F2@1239|Firmicutes,4IHB0@91061|Bacilli,3F9IA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 AFLMLIMI_01050 543734.LCABL_02500 1.9e-187 520.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4HVF8@91061|Bacilli,3FBRX@33958|Lactobacillaceae 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 AFLMLIMI_01051 543734.LCABL_02490 7.68e-174 485.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HHQ0@91061|Bacilli,3FC5T@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain glcR - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AFLMLIMI_01052 543734.LCABL_02480 1.4e-102 303.0 COG3103@1|root,COG3103@2|Bacteria,1VB6H@1239|Firmicutes,4I1GZ@91061|Bacilli,3F7SK@33958|Lactobacillaceae 91061|Bacilli T Sh3 type 3 domain protein - - - - - - - - - - - - LysM,SLAP AFLMLIMI_01053 543734.LCABL_02470 9.06e-317 864.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli,3F3KC@33958|Lactobacillaceae 91061|Bacilli U Component of the transport system for branched-chain amino acids brnQ - - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans AFLMLIMI_01054 543734.LCABL_02460 1.39e-239 661.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr AFLMLIMI_01055 543734.LCABL_02440 0.0 1196.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,3F4E5@33958|Lactobacillaceae 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N AFLMLIMI_01056 543734.LCABL_02430 3.73e-206 570.0 COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,3F3XC@33958|Lactobacillaceae 91061|Bacilli I Dehydrogenase glxR - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 AFLMLIMI_01057 543734.LCABL_02420 1.72e-210 580.0 COG0639@1|root,COG0639@2|Bacteria,1UZK9@1239|Firmicutes,4HG1F@91061|Bacilli,3F5JR@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain prpA3 - 3.1.3.16 ko:K01090 - - - - ko00000,ko01000 - - - Metallophos_2 AFLMLIMI_01058 543734.LCABL_02410 6.97e-172 481.0 COG1108@1|root,COG1108@2|Bacteria,1V0SX@1239|Firmicutes,4HE09@91061|Bacilli,3F4BC@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family znuB - - ko:K02075,ko:K09816 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC-3 AFLMLIMI_01059 543734.LCABL_02400 1.38e-165 463.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3F49M@33958|Lactobacillaceae 91061|Bacilli P ABC transporter adcC - - ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 M00242,M00244,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran AFLMLIMI_01060 543734.LCABL_02390 3.74e-75 224.0 2CICD@1|root,3462T@2|Bacteria,1VZWZ@1239|Firmicutes,4HY4B@91061|Bacilli,3F6T8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01061 543734.LCABL_02290 6.55e-270 745.0 COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,4HB0Y@91061|Bacilli,3F3V0@33958|Lactobacillaceae 91061|Bacilli EG Gluconate gntP - - ko:K03299 - - - - ko00000,ko02000 2.A.8 - - GntP_permease AFLMLIMI_01062 543734.LCABL_02280 0.0 1047.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,3F4R2@33958|Lactobacillaceae 91061|Bacilli G Belongs to the FGGY kinase family gntK - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N AFLMLIMI_01063 543734.LCABL_02270 2.98e-216 597.0 COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,3F4X7@33958|Lactobacillaceae 91061|Bacilli G Dehydrogenase gntZ - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 AFLMLIMI_01064 543734.LCABL_02260 2.1e-185 517.0 COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,4HB9E@91061|Bacilli,3F42G@33958|Lactobacillaceae 91061|Bacilli K rpiR family gntR - - - - - - - - - - - HTH_6,SIS AFLMLIMI_01065 543734.LCABL_02250 8.67e-88 258.0 COG1942@1|root,COG1942@2|Bacteria,1V3SS@1239|Firmicutes,4HI9G@91061|Bacilli,3F6UD@33958|Lactobacillaceae 91061|Bacilli S Tautomerase enzyme yodA - - - - - - - - - - - Tautomerase_2 AFLMLIMI_01066 543734.LCABL_02240 1.4e-204 566.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli,3F9NW@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II iolJ - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU39670 F_bP_aldolase AFLMLIMI_01067 543734.LCABL_02230 4.25e-222 611.0 COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,4HCIM@91061|Bacilli,3F5FP@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) iolE - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 AFLMLIMI_01068 543734.LCABL_02220 3.93e-248 681.0 COG0673@1|root,COG0673@2|Bacteria,1TQJX@1239|Firmicutes,4HAJ8@91061|Bacilli,3F5FQ@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, C-terminal alpha/beta domain iolG2 - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C AFLMLIMI_01069 543734.LCABL_02210 3.92e-246 676.0 COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,4HBTG@91061|Bacilli,3F94F@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA AFLMLIMI_01070 543734.LCABL_02200 0.0 1263.0 COG3962@1|root,COG3962@2|Bacteria,1UI18@1239|Firmicutes,4HCPP@91061|Bacilli,3F9EH@33958|Lactobacillaceae 91061|Bacilli E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) iolD GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - iYO844.BSU39730 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AFLMLIMI_01071 543734.LCABL_02190 6.58e-228 628.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HB78@91061|Bacilli,3FC23@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) iolC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575 2.7.1.92 ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU39740 PfkB AFLMLIMI_01072 543734.LCABL_02180 2.84e-199 551.0 COG3718@1|root,COG3718@2|Bacteria,1TR6M@1239|Firmicutes,4HCDY@91061|Bacilli,3F4TI@33958|Lactobacillaceae 91061|Bacilli G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) iolB - 5.3.1.30 ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08503 RC00541 ko00000,ko00001,ko01000 - - - KduI AFLMLIMI_01073 543734.LCABL_02170 0.0 974.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family iolA GO:0003674,GO:0003824,GO:0004491,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh AFLMLIMI_01074 543734.LCABL_02160 0.0 920.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06609 - - - - ko00000,ko02000 2.A.1.1.26 - - Sugar_tr AFLMLIMI_01075 543734.LCABL_02150 7.14e-187 520.0 COG1349@1|root,COG1349@2|Bacteria,1TTGR@1239|Firmicutes,4HEVD@91061|Bacilli 91061|Bacilli K COG1349 Transcriptional regulators of sugar metabolism iolR - - ko:K06608,ko:K11534 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AFLMLIMI_01076 543734.LCABL_02140 1.36e-209 578.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli,3F3PW@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase yvgN - - - - - - - - - - - Aldo_ket_red AFLMLIMI_01077 543734.LCABL_02130 2.71e-182 506.0 COG1794@1|root,COG1794@2|Bacteria,1V34N@1239|Firmicutes,4HG8W@91061|Bacilli,3F3XZ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aspartate glutamate racemases family racD - 5.1.1.13 ko:K01779 ko00250,ko01054,map00250,map01054 - R00491 RC00302 ko00000,ko00001,ko01000 - - - Asp_Glu_race AFLMLIMI_01078 543734.LCABL_02120 0.0 1008.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,3F3UE@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M AFLMLIMI_01079 543734.LCABL_02110 4.15e-103 298.0 COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,4HW8H@91061|Bacilli,3F6ZK@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N AFLMLIMI_01080 543734.LCABL_02100 2.75e-303 828.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli,3F43S@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 AFLMLIMI_01081 543734.LCABL_02090 2.81e-278 761.0 COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,4HARU@91061|Bacilli,3F479@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase hpk31 - - - - - - - - - - - HATPase_c,HisKA AFLMLIMI_01082 543734.LCABL_02080 1.68e-156 439.0 COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,3F3Y0@33958|Lactobacillaceae 91061|Bacilli K response regulator vanR - - - - - - - - - - - Response_reg,Trans_reg_C AFLMLIMI_01083 543734.LCABL_02070 2.79e-154 434.0 2F4SR@1|root,33XFD@2|Bacteria,1VW0F@1239|Firmicutes,4HWCG@91061|Bacilli,3F6TR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01084 543734.LCABL_02060 0.0 952.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli,3F3XN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH AFLMLIMI_01085 543734.LCABL_02050 1.83e-171 481.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HH7B@91061|Bacilli,3F4JS@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1129) - - - - - - - - - - - - DUF1129 AFLMLIMI_01086 543734.LCABL_02040 9.76e-237 653.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,3F3TK@33958|Lactobacillaceae 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C AFLMLIMI_01087 543734.LCABL_02030 3.26e-40 132.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli,3F823@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF951) yyzM - - - - - - - - - - - DUF951 AFLMLIMI_01088 543734.LCABL_02020 1.11e-201 559.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,3F47R@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc AFLMLIMI_01089 543734.LCABL_02010 1.49e-177 495.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,3F4AE@33958|Lactobacillaceae 91061|Bacilli D Sporulation initiation inhibitor soj GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 AFLMLIMI_01090 543734.LCABL_02000 7.98e-188 523.0 COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,4HAC6@91061|Bacilli,3F4RU@33958|Lactobacillaceae 91061|Bacilli K Belongs to the ParB family noc - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc AFLMLIMI_01091 543734.LCABL_01990 2.27e-167 468.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli,3F3ZX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB AFLMLIMI_01092 543734.LCABL_01980 4.01e-87 256.0 29PCH@1|root,30AAR@2|Bacteria,1U6EK@1239|Firmicutes,4IG6D@91061|Bacilli,3F7R0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01093 543734.LCABL_01970 5.48e-164 458.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli,3F4CH@33958|Lactobacillaceae 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 AFLMLIMI_01094 543734.LCABL_01960 6.15e-139 393.0 COG2085@1|root,COG2085@2|Bacteria,1VW6H@1239|Firmicutes,4HWI6@91061|Bacilli,3F6QU@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored AFLMLIMI_01095 543734.LCABL_01950 6.93e-154 432.0 COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,3F46I@33958|Lactobacillaceae 91061|Bacilli O Removes 5-oxoproline from various penultimate amino acid residues except L-proline pcp GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 AFLMLIMI_01096 543734.LCABL_01940 1.42e-195 545.0 COG3817@1|root,COG3817@2|Bacteria,1TQ17@1239|Firmicutes,4HAJT@91061|Bacilli,3F5QJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF979) - - - - - - - - - - - - DUF979 AFLMLIMI_01097 543734.LCABL_01930 2.66e-147 416.0 COG3819@1|root,COG3819@2|Bacteria,1TT00@1239|Firmicutes,4HE38@91061|Bacilli,3F538@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF969) - - - - - - - - - - - - DUF969 AFLMLIMI_01098 543734.LCABL_01920 1.97e-92 270.0 COG1302@1|root,COG1302@2|Bacteria,1VJRA@1239|Firmicutes,4HXJN@91061|Bacilli,3F692@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp2 - - - - - - - - - - - Asp23 AFLMLIMI_01099 543734.LCABL_01910 8.12e-90 263.0 COG1302@1|root,COG1302@2|Bacteria,1VCNX@1239|Firmicutes,4HKR6@91061|Bacilli,3FB58@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function asp23 - - - - - - - - - - - Asp23 AFLMLIMI_01100 568703.LGG_00229 4.15e-34 117.0 29QCQ@1|root,30BBZ@2|Bacteria,1U7VV@1239|Firmicutes,4IHT8@91061|Bacilli,3FA8J@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01101 543734.LCABL_01890 6.73e-112 323.0 COG1302@1|root,COG1302@2|Bacteria,1VN34@1239|Firmicutes,4HRAM@91061|Bacilli,3F8AH@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - - AFLMLIMI_01102 543734.LCABL_01880 4.95e-53 166.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli,3F7EK@33958|Lactobacillaceae 91061|Bacilli S Transglycosylase associated protein - - - - - - - - - - - - Transgly_assoc AFLMLIMI_01103 543734.LCABL_01870 9.25e-94 273.0 COG3576@1|root,COG3576@2|Bacteria,1V4U5@1239|Firmicutes,4HX4S@91061|Bacilli,3FBB6@33958|Lactobacillaceae 91061|Bacilli S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx AFLMLIMI_01104 543734.LCABL_01860 2.86e-219 606.0 COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,3F4Z6@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C AFLMLIMI_01105 543734.LCABL_01850 2.82e-36 122.0 29QNT@1|root,30BNF@2|Bacteria,1U8D5@1239|Firmicutes,4IIB4@91061|Bacilli,3FAUS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01106 1423816.BACQ01000030_gene1046 5.54e-50 158.0 2930D@1|root,3270J@2|Bacteria,1USWD@1239|Firmicutes,4IG6X@91061|Bacilli,3F7S4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01107 543734.LCABL_01830 1.63e-109 315.0 COG0716@1|root,COG0716@2|Bacteria,1U7EW@1239|Firmicutes,4IHAT@91061|Bacilli,3F9HX@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_1 AFLMLIMI_01108 568703.LGG_00220 4.85e-65 198.0 29Q8B@1|root,30B7C@2|Bacteria,1U7P0@1239|Firmicutes,4IHK9@91061|Bacilli,3F9YT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01109 543734.LCABL_01810 5.12e-117 335.0 29QKG@1|root,30BK4@2|Bacteria,1U898@1239|Firmicutes,4II73@91061|Bacilli,3FAQ9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01110 1423790.BN53_05765 1.47e-07 50.4 29PI4@1|root,30AG9@2|Bacteria,1U6MC@1239|Firmicutes,4IGE7@91061|Bacilli,3F858@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01111 543734.LCABL_01790 6.45e-74 222.0 COG4272@1|root,COG4272@2|Bacteria,1VAPQ@1239|Firmicutes,4IRG9@91061|Bacilli,3FBP6@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1634) ywjH - - - - - - - - - - - DUF1634 AFLMLIMI_01112 543734.LCABL_01780 8.76e-178 498.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,3FCAW@33958|Lactobacillaceae 91061|Bacilli S Sulfite exporter TauE/SafE yunE - - ko:K07090 - - - - ko00000 - - - TauE AFLMLIMI_01113 543734.LCABL_01770 5.99e-287 787.0 COG1512@1|root,COG1512@2|Bacteria,1VHE2@1239|Firmicutes,4HJHN@91061|Bacilli,3F75Q@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase AFLMLIMI_01114 543734.LCABL_01760 6.18e-150 421.0 29DQI@1|root,300NC@2|Bacteria,1U55V@1239|Firmicutes,4IEX6@91061|Bacilli,3F4UQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01115 543734.LCABL_01750 0.0 898.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli,3F449@33958|Lactobacillaceae 91061|Bacilli C NADH oxidase nox - 1.6.3.4 ko:K17869 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim AFLMLIMI_01116 543734.LCABL_01740 0.0 1229.0 COG4529@1|root,COG4529@2|Bacteria,1UZ38@1239|Firmicutes,4HDXC@91061|Bacilli,3F4ZH@33958|Lactobacillaceae 91061|Bacilli S FAD-NAD(P)-binding fnq20 - - - - - - - - - - - NAD_binding_9 AFLMLIMI_01117 1423732.BALS01000042_gene2692 7.22e-141 405.0 COG1396@1|root,COG1396@2|Bacteria,1VD8E@1239|Firmicutes,4HMD2@91061|Bacilli,3F8P8@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins ywdE - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 AFLMLIMI_01118 1423816.BACQ01000030_gene1058 2.26e-283 785.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F6VM@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AFLMLIMI_01119 543734.LCABL_01730 2.12e-275 753.0 COG1537@1|root,COG1537@2|Bacteria,1UPQ9@1239|Firmicutes,4IV8X@91061|Bacilli,3FC0K@33958|Lactobacillaceae 91061|Bacilli S nuclear-transcribed mRNA catabolic process, no-go decay - - - - - - - - - - - - - AFLMLIMI_01120 543734.LCABL_01720 4.85e-102 296.0 2BFZ1@1|root,329UX@2|Bacteria,1W1ZW@1239|Firmicutes,4I0E0@91061|Bacilli 91061|Bacilli S NUDIX domain - - - - - - - - - - - - NUDIX AFLMLIMI_01122 1423816.BACQ01000030_gene1065 1.15e-25 102.0 2BFQS@1|root,329JG@2|Bacteria,1TZIV@1239|Firmicutes,4IGKR@91061|Bacilli,3F8FT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01123 543734.LCABL_01690 0.0 1047.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AFLMLIMI_01124 543734.LCABL_01680 0.0 1645.0 COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,4HC2J@91061|Bacilli,3F3TZ@33958|Lactobacillaceae 91061|Bacilli G Phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N AFLMLIMI_01126 543734.LCABL_01660 0.0 905.0 COG0477@1|root,COG2814@2|Bacteria,1VSW8@1239|Firmicutes,4HUQC@91061|Bacilli,3F4AW@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator bmr3 - - - - - - - - - - - MFS_1 AFLMLIMI_01127 543734.LCABL_01650 1.94e-129 368.0 COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,4HG0Y@91061|Bacilli,3F5CS@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family yobS GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - - - - - - - - - - TetR_N,WHG AFLMLIMI_01128 543734.LCABL_01640 0.0 916.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli,3F3Y3@33958|Lactobacillaceae 91061|Bacilli V domain protein yhgE - - ko:K01421 - - - - ko00000 - - - ABC2_membrane_3,DUF3533 AFLMLIMI_01129 543734.LCABL_01630 4.22e-60 185.0 COG0011@1|root,COG0011@2|Bacteria,1VC4R@1239|Firmicutes,4HSQA@91061|Bacilli,3F7GK@33958|Lactobacillaceae 91061|Bacilli S Thiamine-binding protein - - - - - - - - - - - - Thiamine_BP AFLMLIMI_01130 543734.LCABL_01620 5.47e-178 495.0 COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli,3F62T@33958|Lactobacillaceae 91061|Bacilli L Base excision DNA repair protein, HhH-GPD family - - - ko:K07457 - - - - ko00000 - - - HhH-GPD AFLMLIMI_01131 543734.LCABL_01610 1.65e-204 565.0 COG0639@1|root,COG0639@2|Bacteria,1V1HN@1239|Firmicutes,4HHQ3@91061|Bacilli,3FCCD@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain pphA - 3.1.3.16 ko:K07313 - - - - ko00000,ko01000 - - - Metallophos AFLMLIMI_01132 543734.LCABL_01600 1.07e-282 773.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase AFLMLIMI_01133 543734.LCABL_01590 0.0 876.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,3F3NB@33958|Lactobacillaceae 91061|Bacilli L recombination factor protein RarA rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N AFLMLIMI_01134 543734.LCABL_01580 9.02e-76 226.0 2C1B3@1|root,302T3@2|Bacteria,1U6JW@1239|Firmicutes,4IGCF@91061|Bacilli,3F821@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01135 543734.LCABL_01570 1.17e-209 582.0 COG3152@1|root,COG3152@2|Bacteria,1VP5A@1239|Firmicutes,4IFSK@91061|Bacilli,3F6XM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 AFLMLIMI_01136 543734.LCABL_01560 0.0 954.0 COG3711@1|root,COG3711@2|Bacteria,1VBUE@1239|Firmicutes,4HN8V@91061|Bacilli,3FBAD@33958|Lactobacillaceae 91061|Bacilli L Mga helix-turn-helix domain - - - - - - - - - - - - Mga AFLMLIMI_01138 543734.LCABL_01540 2.43e-242 667.0 COG4072@1|root,COG4072@2|Bacteria,1VCXS@1239|Firmicutes,4HKJG@91061|Bacilli,3F5HA@33958|Lactobacillaceae 91061|Bacilli S Cell surface protein ynjC - - - - - - - - - - - DUF3324,DUF916 AFLMLIMI_01139 543734.LCABL_01530 8.3e-171 477.0 COG4886@1|root,COG4886@2|Bacteria,1V9D9@1239|Firmicutes,4HJPY@91061|Bacilli,3F7MH@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL AFLMLIMI_01140 543734.LCABL_01520 2e-167 469.0 29WH0@1|root,30I33@2|Bacteria,1U57C@1239|Firmicutes,4IEYT@91061|Bacilli,3F511@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL AFLMLIMI_01142 543734.LCABL_01490 0.0 1195.0 2F70X@1|root,33ZGK@2|Bacteria,1VXAH@1239|Firmicutes,4HXTD@91061|Bacilli,3F9HI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01143 543734.LCABL_01470 1.04e-134 381.0 COG1670@1|root,COG1670@2|Bacteria,1VCN3@1239|Firmicutes,4HKNF@91061|Bacilli,3F7GP@33958|Lactobacillaceae 91061|Bacilli J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins yoaA - - - - - - - - - - - Acetyltransf_3 AFLMLIMI_01144 568703.LGG_00179 6.64e-39 132.0 29Q9W@1|root,30B8Z@2|Bacteria,1U7RE@1239|Firmicutes,4IHNS@91061|Bacilli,3FA2D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01145 568703.LGG_00178 1.68e-227 627.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,3F4PB@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqA - - ko:K15975 - - - - ko00000 - - - Glyoxalase AFLMLIMI_01146 568703.LGG_00169 4.89e-61 188.0 COG1416@1|root,COG1416@2|Bacteria,1VEYT@1239|Firmicutes,4HQQN@91061|Bacilli,3FBBQ@33958|Lactobacillaceae 91061|Bacilli S DsrE/DsrF-like family - - - ko:K09004 - - - - ko00000 - - - DrsE AFLMLIMI_01147 543734.LCABL_01430 0.0 885.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,3F44D@33958|Lactobacillaceae 91061|Bacilli S permease XK27_07275 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease AFLMLIMI_01148 543734.LCABL_01420 2.42e-72 218.0 2EGA1@1|root,33A1U@2|Bacteria,1VPXU@1239|Firmicutes,4HS3Y@91061|Bacilli,3F7WK@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1516) - - - - - - - - - - - - DUF1516 AFLMLIMI_01149 543734.LCABL_01410 6.55e-72 217.0 COG3759@1|root,COG3759@2|Bacteria,1VAVU@1239|Firmicutes,4HQHN@91061|Bacilli,3F7NA@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1304) - - - ko:K08987 - - - - ko00000 - - - DUF1304 AFLMLIMI_01150 543734.LCABL_01400 1.42e-207 577.0 COG0604@1|root,COG0604@2|Bacteria,1V2UJ@1239|Firmicutes,4HG2A@91061|Bacilli,3F52N@33958|Lactobacillaceae 91061|Bacilli C alcohol dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_zinc_N AFLMLIMI_01151 543734.LCABL_01390 1.11e-111 321.0 COG1846@1|root,COG1846@2|Bacteria,1W4X8@1239|Firmicutes,4I172@91061|Bacilli,3F8CB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - MarR AFLMLIMI_01152 543734.LCABL_01380 9.97e-59 182.0 298HG@1|root,2ZKVW@2|Bacteria,1W538@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - AFLMLIMI_01153 543734.LCABL_01370 3.91e-244 670.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD3 - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C AFLMLIMI_01154 543734.LCABL_01360 2.47e-117 335.0 COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F6RF@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase adaB GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 ko:K00567,ko:K10778,ko:K13531 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,Methyltransf_1N AFLMLIMI_01155 543734.LCABL_01350 2.61e-261 715.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli,3F41Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N AFLMLIMI_01156 543734.LCABL_01340 2.67e-56 174.0 29QF0@1|root,30BEB@2|Bacteria,1U7ZU@1239|Firmicutes,4IHX8@91061|Bacilli,3FAD7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01157 543734.LCABL_01330 4.18e-263 720.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HDUZ@91061|Bacilli,3F3NK@33958|Lactobacillaceae 91061|Bacilli V LD-carboxypeptidase mccF - - - - - - - - - - - Peptidase_S66 AFLMLIMI_01158 543734.LCABL_01320 1.57e-235 647.0 COG0671@1|root,COG0671@2|Bacteria,1V7AD@1239|Firmicutes,4HJB7@91061|Bacilli,3F4Q4@33958|Lactobacillaceae 91061|Bacilli I PAP2 superfamily yveB - - - - - - - - - - - PAP2 AFLMLIMI_01159 543734.LCABL_01310 2.66e-57 178.0 COG3877@1|root,COG3877@2|Bacteria,1VGSH@1239|Firmicutes,4HQ68@91061|Bacilli,3F84H@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 AFLMLIMI_01160 543734.LCABL_01300 1.29e-50 161.0 2ENBH@1|root,33FZ4@2|Bacteria,1VM60@1239|Firmicutes,4HREG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01161 543734.LCABL_01270 0.0 894.0 COG0277@1|root,COG0277@2|Bacteria,1U53V@1239|Firmicutes,4HDF7@91061|Bacilli 91061|Bacilli C COG0277 FAD FMN-containing dehydrogenases yvdP - - - - - - - - - - - BBE,FAD_binding_4 AFLMLIMI_01162 543734.LCABL_01260 5.46e-184 511.0 COG0639@1|root,COG0639@2|Bacteria,1V45T@1239|Firmicutes,4HHSG@91061|Bacilli,3F6PM@33958|Lactobacillaceae 91061|Bacilli T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 AFLMLIMI_01163 543734.LCABL_01250 0.0 899.0 2DBW0@1|root,2ZBE0@2|Bacteria,1V57P@1239|Firmicutes,4HH8K@91061|Bacilli,3F5BJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - PA AFLMLIMI_01164 543734.LCABL_01240 2.22e-130 371.0 COG1476@1|root,COG1476@2|Bacteria,1V6QF@1239|Firmicutes,4HIIT@91061|Bacilli,3F7M5@33958|Lactobacillaceae 91061|Bacilli K Bacteriophage CI repressor helix-turn-helix domain - - - - - - - - - - - - DUF3955,HTH_3 AFLMLIMI_01165 543734.LCABL_01230 1.41e-162 457.0 2E7NX@1|root,33B9D@2|Bacteria,1VPN2@1239|Firmicutes,4HS0V@91061|Bacilli,3F7ZV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01166 543734.LCABL_01220 0.0 1483.0 COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli,3F435@33958|Lactobacillaceae 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD AFLMLIMI_01167 543734.LCABL_01210 2.18e-169 474.0 COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,4HIS1@91061|Bacilli,3F5JZ@33958|Lactobacillaceae 91061|Bacilli S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 AFLMLIMI_01168 543734.LCABL_01200 2.26e-215 595.0 COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,4HBHF@91061|Bacilli,3F612@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yxlF - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 AFLMLIMI_01169 543734.LCABL_01190 1.91e-46 149.0 2E3AZ@1|root,32YAF@2|Bacteria,1VF37@1239|Firmicutes,4HP14@91061|Bacilli,3F8CH@33958|Lactobacillaceae 91061|Bacilli S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N AFLMLIMI_01170 543734.LCABL_01180 3.04e-259 711.0 COG1476@1|root,COG1476@2|Bacteria,1TNYC@1239|Firmicutes,4HF5V@91061|Bacilli,3F58D@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AFLMLIMI_01171 543734.LCABL_01170 3.31e-204 565.0 COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,4HBNZ@91061|Bacilli,3F4XG@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain lysR5 - - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_01172 543734.LCABL_01160 0.0 1473.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HVA4@91061|Bacilli,3F55J@33958|Lactobacillaceae 91061|Bacilli P Cation transporter/ATPase, N-terminus - - 3.6.3.6 ko:K01535 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.3 - - Cation_ATPase_N,E1-E2_ATPase,Hydrolase AFLMLIMI_01173 543734.LCABL_01150 4.34e-75 224.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HFYU@91061|Bacilli,3FB53@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor cadC5 - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 AFLMLIMI_01174 543734.LCABL_01140 0.0 1139.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase AFLMLIMI_01175 543734.LCABL_01130 9.64e-317 862.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,3F3RQ@33958|Lactobacillaceae 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt AFLMLIMI_01176 568703.LGG_00128 1.42e-153 437.0 COG1737@1|root,COG1737@2|Bacteria,1TPIX@1239|Firmicutes,4HBJA@91061|Bacilli,3F5WQ@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family yleF - - - - - - - - - - - HTH_6,SIS AFLMLIMI_01177 568703.LGG_00126 1.08e-165 469.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 AFLMLIMI_01178 568703.LGG_00125 0.0 979.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts32BC - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AFLMLIMI_01179 543734.LCABL_01120 2.21e-275 753.0 2CC2J@1|root,309K5@2|Bacteria,1U598@1239|Firmicutes,4IF0I@91061|Bacilli,3F58S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01180 543734.LCABL_01110 0.0 868.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,3F4MW@33958|Lactobacillaceae 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaB GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C AFLMLIMI_01181 543734.LCABL_01100 1.35e-97 284.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli,3F68P@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N AFLMLIMI_01182 543734.LCABL_01090 0.0 1283.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli,3F3TY@33958|Lactobacillaceae 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 AFLMLIMI_01184 543734.LCABL_01070 4.57e-123 351.0 29XQD@1|root,30JG1@2|Bacteria,1TVFA@1239|Firmicutes,4I1PS@91061|Bacilli,3FAZJ@33958|Lactobacillaceae 91061|Bacilli S Phospholipase A2 - - - - - - - - - - - - Phospholip_A2_1 AFLMLIMI_01185 543734.LCABL_01060 2.98e-189 527.0 COG0697@1|root,COG0697@2|Bacteria,1V86F@1239|Firmicutes,4HJWZ@91061|Bacilli,3F4CV@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA AFLMLIMI_01186 543734.LCABL_01050 1.35e-97 283.0 COG0494@1|root,COG0494@2|Bacteria,1VK3S@1239|Firmicutes,4IHJ0@91061|Bacilli,3F9X5@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain - - - - - - - - - - - - NUDIX AFLMLIMI_01187 543734.LCABL_01040 8.13e-82 242.0 29PM4@1|root,30AVT@2|Bacteria,1U75Z@1239|Firmicutes,4IH0M@91061|Bacilli,3F90S@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01188 543734.LCABL_01030 3.23e-248 682.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli,3F4S9@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC AFLMLIMI_01189 543734.LCABL_01020 5.72e-238 654.0 COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli,3F4F7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase AFLMLIMI_01190 543734.LCABL_01010 0.0 894.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 AFLMLIMI_01191 543734.LCABL_01000 0.0 882.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli,3F3VJ@33958|Lactobacillaceae 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC AFLMLIMI_01192 543734.LCABL_00990 4.4e-116 338.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,3F3U0@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep AFLMLIMI_01193 543734.LCABL_00980 6.4e-282 769.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli,3F419@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 AFLMLIMI_01194 543734.LCABL_00970 6.02e-216 596.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli,3F4UH@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS AFLMLIMI_01195 543734.LCABL_00960 2.21e-179 499.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli,3F3MA@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N AFLMLIMI_01197 543734.LCABL_00860 3.66e-166 465.0 2BJ44@1|root,32DD4@2|Bacteria,1U7J0@1239|Firmicutes,4IHFT@91061|Bacilli,3F9SG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01199 543734.LCABL_00850 6.04e-139 392.0 COG1309@1|root,COG1309@2|Bacteria,1V9ST@1239|Firmicutes,4HP6S@91061|Bacilli,3F5J7@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AFLMLIMI_01200 543734.LCABL_00840 0.0 1073.0 COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1TPV3@1239|Firmicutes,4HCJN@91061|Bacilli,3F5DE@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 AFLMLIMI_01201 543734.LCABL_00830 6.19e-264 724.0 2C353@1|root,309Q7@2|Bacteria,1U5H7@1239|Firmicutes,4IF82@91061|Bacilli,3F5XZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01202 543734.LCABL_00820 7.2e-176 489.0 28K10@1|root,2Z9QW@2|Bacteria,1VU2U@1239|Firmicutes,4HVDF@91061|Bacilli,3F4AC@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4918) - - - - - - - - - - - - DUF4918 AFLMLIMI_01203 543734.LCABL_00800 1.03e-101 295.0 COG1762@1|root,COG1762@2|Bacteria,1VBAN@1239|Firmicutes,4IPY0@91061|Bacilli 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 AFLMLIMI_01204 543734.LCABL_00790 1.47e-60 186.0 COG3414@1|root,COG3414@2|Bacteria,1VB8X@1239|Firmicutes,4IR82@91061|Bacilli 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB AFLMLIMI_01205 543734.LCABL_00780 4.86e-297 811.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HBAD@91061|Bacilli,3F4Y4@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT AFLMLIMI_01206 543734.LCABL_00760 5.89e-234 645.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,3F50X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 AFLMLIMI_01207 543734.LCABL_00750 2.46e-174 487.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,3F5AK@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS AFLMLIMI_01208 543734.LCABL_00740 6.7e-135 382.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HN68@91061|Bacilli,3F4B6@33958|Lactobacillaceae 91061|Bacilli E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI AFLMLIMI_01209 543734.LCABL_00730 7.1e-293 799.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli,3F4DT@33958|Lactobacillaceae 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP AFLMLIMI_01210 543734.LCABL_00720 3.25e-181 505.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli,3F50S@33958|Lactobacillaceae 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA AFLMLIMI_01211 543734.LCABL_00710 1.23e-149 421.0 COG0664@1|root,COG0664@2|Bacteria,1UZT0@1239|Firmicutes,4HFR2@91061|Bacilli,3FBKF@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, cAMP Regulatory protein flp - - ko:K21562 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding AFLMLIMI_01212 543734.LCABL_00700 5.98e-131 372.0 COG0783@1|root,COG0783@2|Bacteria,1VB1X@1239|Firmicutes,4HMJG@91061|Bacilli,3F4SN@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Dps family dpsB - - - - - - - - - - - Ferritin AFLMLIMI_01213 543734.LCABL_00680 3.61e-46 148.0 COG2608@1|root,COG2608@2|Bacteria,1VFJ8@1239|Firmicutes,4HNY2@91061|Bacilli,3F830@33958|Lactobacillaceae 91061|Bacilli P Heavy-metal-associated domain copZ - - - - - - - - - - - HMA AFLMLIMI_01214 543734.LCABL_00670 0.0 1122.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4T3@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,Hydrolase AFLMLIMI_01217 543734.LCABL_00660 1.72e-285 781.0 COG1125@1|root,COG2905@1|root,COG1125@2|Bacteria,COG2905@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein opuCA - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12845,iYO844.BSU33730 ABC_tran,CBS AFLMLIMI_01218 543734.LCABL_00650 2.28e-136 387.0 COG1174@1|root,COG1174@2|Bacteria,1TSX8@1239|Firmicutes,4HC1D@91061|Bacilli,3F4EM@33958|Lactobacillaceae 91061|Bacilli E ABC transporter permease opuCB - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 AFLMLIMI_01219 543734.LCABL_00640 3.55e-222 612.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HARV@91061|Bacilli,3F420@33958|Lactobacillaceae 91061|Bacilli M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) opuCC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iSB619.SA_RS12835 OpuAC AFLMLIMI_01220 543734.LCABL_00630 7.92e-142 402.0 COG1174@1|root,COG1174@2|Bacteria,1TQ5C@1239|Firmicutes,4HAVM@91061|Bacilli,3F51B@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component opuCD GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337 - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - iYO844.BSU33800 BPD_transp_1 AFLMLIMI_01224 1121085.AUCI01000001_gene3609 6.66e-23 99.8 COG0179@1|root,COG0179@2|Bacteria,1UZ6U@1239|Firmicutes,4HCE0@91061|Bacilli,1ZARQ@1386|Bacillus 91061|Bacilli Q Domain of unknown function (DUF2437) - - - - - - - - - - - - DUF2437,FAA_hydrolase AFLMLIMI_01225 543734.LCABL_29070 1.64e-128 370.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,3F43P@33958|Lactobacillaceae 91061|Bacilli G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II AFLMLIMI_01226 1114972.AUAW01000006_gene2509 1.11e-134 390.0 COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,4HBBU@91061|Bacilli,3F5GZ@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel sga - 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 - - - AP_endonuc_2 AFLMLIMI_01227 658659.HMPREF0983_00682 1.62e-157 478.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UW53@1239|Firmicutes,3VSX2@526524|Erysipelotrichia 526524|Erysipelotrichia GKT Mga helix-turn-helix domain - - - - - - - - - - - - Mga,PRD,PTS_EIIA_2 AFLMLIMI_01228 908340.HMPREF9406_4172 8.69e-202 571.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,247MD@186801|Clostridia,36DWJ@31979|Clostridiaceae 186801|Clostridia S PTS system - - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT AFLMLIMI_01229 908340.HMPREF9406_4173 1.31e-36 125.0 COG3414@1|root,COG3414@2|Bacteria,1VFJK@1239|Firmicutes,24KGU@186801|Clostridia,36NHP@31979|Clostridiaceae 186801|Clostridia G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB AFLMLIMI_01230 1437600.JDUI01000016_gene1108 2.37e-50 167.0 COG0794@1|root,COG0794@2|Bacteria,2IBB3@201174|Actinobacteria,4CZHS@85004|Bifidobacteriales 201174|Actinobacteria G SIS domain hxlB - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS AFLMLIMI_01231 1461580.CCAS010000054_gene3704 7.57e-41 145.0 COG0269@1|root,COG0269@2|Bacteria,1V4B6@1239|Firmicutes,4HHY5@91061|Bacilli,1ZQF2@1386|Bacillus 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family - - 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AFLMLIMI_01232 908340.HMPREF9406_4174 5.09e-40 139.0 COG1762@1|root,COG1762@2|Bacteria,1V8PU@1239|Firmicutes,24P2G@186801|Clostridia,36KVN@31979|Clostridiaceae 186801|Clostridia H phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 AFLMLIMI_01233 352165.HMPREF7215_1702 9.17e-75 235.0 COG0684@1|root,COG0684@2|Bacteria 2|Bacteria H ribonuclease inhibitor activity - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - RraA-like AFLMLIMI_01234 543734.LCABL_00610 2.34e-140 396.0 COG1309@1|root,COG1309@2|Bacteria,1V95E@1239|Firmicutes,4HH9M@91061|Bacilli,3F6ZH@33958|Lactobacillaceae 91061|Bacilli K Tetracycline repressor, C-terminal all-alpha domain - - - ko:K22106 - - - - ko00000,ko03000 - - - TetR_C_10,TetR_N AFLMLIMI_01235 543734.LCABL_00600 0.0 1444.0 COG1511@1|root,COG2409@1|root,COG1511@2|Bacteria,COG2409@2|Bacteria,1TQ7C@1239|Firmicutes,4HBM6@91061|Bacilli,3FCCY@33958|Lactobacillaceae 91061|Bacilli S MMPL family ydgH - - ko:K06994 - - - - ko00000 - - - MMPL AFLMLIMI_01237 543734.LCABL_00580 2.19e-306 838.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 AFLMLIMI_01238 543734.LCABL_00570 0.0 975.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli,3F46B@33958|Lactobacillaceae 91061|Bacilli V ABC-type multidrug transport system, ATPase and permease components - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_01239 543734.LCABL_00560 1.58e-199 554.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4I40C@91061|Bacilli,3F837@33958|Lactobacillaceae 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family - - - - - - - - - - - - HTH_3 AFLMLIMI_01240 568703.LGG_00063 2.02e-71 216.0 COG3576@1|root,COG3576@2|Bacteria,1VGE7@1239|Firmicutes,4HNE7@91061|Bacilli,3F6YB@33958|Lactobacillaceae 91061|Bacilli S pyridoxamine 5-phosphate - - - - - - - - - - - - Putative_PNPOx AFLMLIMI_01241 353496.LBU_1303 1.66e-37 143.0 COG2207@1|root,COG2207@2|Bacteria,1UVA5@1239|Firmicutes,4IFGR@91061|Bacilli,3F6FF@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_18 AFLMLIMI_01242 208596.CAR_c21070 1.06e-99 303.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli 91061|Bacilli C Electron transfer flavoprotein etfA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 ko:K03522,ko:K22432 - - - - ko00000,ko01000,ko04147 - - - ETF,ETF_alpha AFLMLIMI_01243 1423807.BACO01000041_gene1250 5.24e-100 299.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,4H9QY@91061|Bacilli,3F3YN@33958|Lactobacillaceae 91061|Bacilli C Electron transfer flavoprotein domain fixA - - ko:K03521 - - - - ko00000 - - - ETF AFLMLIMI_01244 1302286.BAOT01000009_gene652 3.44e-166 476.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HA2A@91061|Bacilli,3F40U@33958|Lactobacillaceae 91061|Bacilli I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249,ko:K18244 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N AFLMLIMI_01246 1423816.BACQ01000036_gene1477 1.33e-41 139.0 2FI7A@1|root,349ZW@2|Bacteria,1W0B2@1239|Firmicutes,4HY9R@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - EntA_Immun AFLMLIMI_01247 543734.LCABL_00550 1.16e-72 218.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - ps105 - - - - - - - - - - - - AFLMLIMI_01249 543734.LCABL_00540 2.13e-160 449.0 COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,4HGG8@91061|Bacilli,3F69H@33958|Lactobacillaceae 91061|Bacilli K FCD domain kdgR - - - - - - - - - - - FCD,GntR AFLMLIMI_01250 543734.LCABL_00520 6.9e-150 422.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase AFLMLIMI_01251 543734.LCABL_00510 1.07e-183 512.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4HPR4@91061|Bacilli,3F5HF@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi AFLMLIMI_01252 543734.LCABL_00500 6.28e-34 117.0 29PUF@1|root,30ASK@2|Bacteria,1U71Y@1239|Firmicutes,4IGWE@91061|Bacilli,3F8VI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01254 543734.LCABL_00480 1.76e-64 197.0 COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HNDZ@91061|Bacilli,3F7IU@33958|Lactobacillaceae 91061|Bacilli S Branched-chain amino acid transport protein (AzlD) azlD - - - - - - - - - - - AzlD AFLMLIMI_01255 543734.LCABL_00470 1.95e-159 447.0 COG1296@1|root,COG1296@2|Bacteria,1U49T@1239|Firmicutes,4HDIJ@91061|Bacilli,3F45S@33958|Lactobacillaceae 91061|Bacilli E branched-chain amino acid azlC - - - - - - - - - - - AzlC AFLMLIMI_01256 945021.TEH_04260 4.32e-98 293.0 28KWY@1|root,2ZAD1@2|Bacteria,1VAA9@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - AFLMLIMI_01257 485916.Dtox_1835 7.7e-83 263.0 28J1N@1|root,2Z8YI@2|Bacteria,1TSQU@1239|Firmicutes,24F7K@186801|Clostridia 186801|Clostridia S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii AFLMLIMI_01258 543734.LCABL_00430 2.32e-124 355.0 29QSZ@1|root,30BSU@2|Bacteria,1U8KU@1239|Firmicutes,4IIIV@91061|Bacilli,3FB3B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01259 543734.LCABL_00400 6.62e-143 404.0 COG2364@1|root,COG2364@2|Bacteria,1VQW3@1239|Firmicutes,4HV4F@91061|Bacilli,3F64W@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - AFLMLIMI_01260 543734.LCABL_00390 0.0 992.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AFLMLIMI_01261 1140001.I571_00212 1.89e-53 183.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HZ6P@91061|Bacilli,4AZI4@81852|Enterococcaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AFLMLIMI_01263 543734.LCABL_00370 4.55e-67 204.0 29Q91@1|root,30B85@2|Bacteria,1U7Q9@1239|Firmicutes,4IHMK@91061|Bacilli,3FA0E@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01264 543734.LCABL_00360 2.37e-306 838.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp AFLMLIMI_01268 543734.LCABL_00340 3.84e-145 409.0 COG1309@1|root,COG1309@2|Bacteria,1V3R8@1239|Firmicutes,4HBEK@91061|Bacilli,3F75F@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AFLMLIMI_01269 543734.LCABL_00330 8.19e-212 585.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli,3F4B8@33958|Lactobacillaceae 91061|Bacilli P CorA-like Mg2+ transporter protein - - - - - - - - - - - - CorA AFLMLIMI_01270 543734.LCABL_00320 1.41e-132 377.0 COG3548@1|root,COG3548@2|Bacteria,1V803@1239|Firmicutes,4IRHS@91061|Bacilli,3F6KM@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 AFLMLIMI_01271 568703.LGG_00037 1.38e-158 447.0 COG0730@1|root,COG0730@2|Bacteria,1VR9G@1239|Firmicutes,4HV4W@91061|Bacilli,3F3TR@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE AFLMLIMI_01272 543734.LCABL_00300 0.0 1399.0 COG3409@1|root,COG3409@2|Bacteria,1TPV1@1239|Firmicutes,4HCRA@91061|Bacilli,3F5J4@33958|Lactobacillaceae 91061|Bacilli M peptidoglycan-binding domain-containing protein ybfG - - - - - - - - - - - DUF1906,PG_binding_1 AFLMLIMI_01275 543734.LCABL_00280 1.65e-63 194.0 29PRI@1|root,30APR@2|Bacteria,1U6YE@1239|Firmicutes,4IGSK@91061|Bacilli,3F8Q9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01276 543734.LCABL_00270 1.77e-196 544.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3ZW@33958|Lactobacillaceae 91061|Bacilli G Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 AFLMLIMI_01277 543734.LCABL_00260 1.68e-127 362.0 COG1309@1|root,COG1309@2|Bacteria,1VI1M@1239|Firmicutes,4HPZV@91061|Bacilli,3F530@33958|Lactobacillaceae 91061|Bacilli K transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N AFLMLIMI_01278 543734.LCABL_00250 1.76e-165 462.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli,3F3YU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_01279 543734.LCABL_00240 0.0 1574.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli,3F4HF@33958|Lactobacillaceae 91061|Bacilli V ABC transporter permease ylbB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD AFLMLIMI_01280 543734.LCABL_00230 1.87e-191 543.0 COG3942@1|root,COG4942@1|root,COG3942@2|Bacteria,COG4942@2|Bacteria,1VCXB@1239|Firmicutes,4HMCB@91061|Bacilli,3F4ZY@33958|Lactobacillaceae 91061|Bacilli D CHAP domain p40 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP AFLMLIMI_01283 543734.LCABL_00200 1.44e-180 504.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4HPR4@91061|Bacilli,3F5HF@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi AFLMLIMI_01286 543734.LCABL_00170 9.81e-138 390.0 COG3548@1|root,COG3548@2|Bacteria,1VFW9@1239|Firmicutes,4HR1J@91061|Bacilli,3F4JD@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) - - - - - - - - - - - - DUF1211 AFLMLIMI_01287 641146.HMPREF9020_01154 1.29e-299 817.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_01288 543734.LCABL_00160 8.07e-40 132.0 2B5YU@1|root,31YUW@2|Bacteria,1U6T8@1239|Firmicutes,4IGM0@91061|Bacilli,3F8G7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01289 543734.LCABL_00150 3.29e-228 630.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F3ZH@33958|Lactobacillaceae 91061|Bacilli C Cytochrome bd terminal oxidase subunit II - - - - - - - - - - - - Cyt_bd_oxida_II AFLMLIMI_01290 543734.LCABL_00140 0.0 983.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F5E6@33958|Lactobacillaceae 91061|Bacilli C Cytochrome bd terminal oxidase subunit I cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I AFLMLIMI_01291 1423732.BALS01000057_gene2844 3.26e-48 154.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli,3F7CY@33958|Lactobacillaceae 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 AFLMLIMI_01292 568703.LGG_00012 1.54e-114 331.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB AFLMLIMI_01293 543734.LCABL_00090 1.36e-65 199.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,3F6ZY@33958|Lactobacillaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 AFLMLIMI_01294 543734.LCABL_00080 5.2e-98 285.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB AFLMLIMI_01295 543734.LCABL_00070 5.22e-163 456.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,3F4M3@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC AFLMLIMI_01296 543734.LCABL_00060 0.0 1656.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,3F3YM@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV AFLMLIMI_01297 543734.LCABL_00050 0.0 1294.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3F48M@33958|Lactobacillaceae 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim AFLMLIMI_01298 543734.LCABL_00040 1.06e-258 710.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N AFLMLIMI_01299 543734.LCABL_00030 4.07e-43 140.0 COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,4HNMC@91061|Bacilli,3F803@33958|Lactobacillaceae 91061|Bacilli S S4 domain protein YaaA yaaA - - ko:K14761 - - - - ko00000,ko03009 - - - S4_2 AFLMLIMI_01300 543734.LCABL_00020 8.4e-260 713.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli,3F3ZQ@33958|Lactobacillaceae 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 AFLMLIMI_01301 543734.LCABL_00010 0.0 878.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,3F3YA@33958|Lactobacillaceae 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N AFLMLIMI_01302 543734.LCABL_31270 3.26e-23 88.6 COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,4HR2Z@91061|Bacilli,3F81W@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 AFLMLIMI_01303 543734.LCABL_31260 2.99e-77 233.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,3F6GS@33958|Lactobacillaceae 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P AFLMLIMI_01304 543734.LCABL_31250 4.53e-179 501.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli,3F3SD@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP AFLMLIMI_01305 543734.LCABL_31240 1.42e-170 477.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli,3F5WG@33958|Lactobacillaceae 91061|Bacilli S R3H domain protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H AFLMLIMI_01307 543734.LCABL_31230 0.0 879.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N AFLMLIMI_01308 543734.LCABL_31220 0.0 1249.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,3F454@33958|Lactobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc AFLMLIMI_01310 543734.LCABL_31200 3.8e-175 489.0 COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,4HBW1@91061|Bacilli,3F4XE@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter labL - - - - - - - - - - - ThrE AFLMLIMI_01311 543734.LCABL_31190 1.48e-104 303.0 COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,4HJ1Y@91061|Bacilli,3F706@33958|Lactobacillaceae 91061|Bacilli S Threonine/Serine exporter, ThrE - - - - - - - - - - - - ThrE_2 AFLMLIMI_01312 543734.LCABL_31180 5.35e-289 789.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli,3FC42@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 amd - - - - - - - - - - - M20_dimer,Peptidase_M20 AFLMLIMI_01313 543734.LCABL_31170 5.21e-254 697.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli,3F4E4@33958|Lactobacillaceae 91061|Bacilli C dehydrogenase ypjH - - ko:K08317 - - - - ko00000,ko01000 - - - Fe-ADH AFLMLIMI_01314 568703.LGG_02923 0.0 2058.0 COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1VE5U@1239|Firmicutes,4ITNN@91061|Bacilli,3FBXI@33958|Lactobacillaceae 91061|Bacilli M Leucine rich repeats (6 copies) - - - - - - - - - - - - Gram_pos_anchor,LRR_5 AFLMLIMI_01315 543734.LCABL_31140 2.07e-264 726.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HBY9@91061|Bacilli,3F5FN@33958|Lactobacillaceae 91061|Bacilli V MacB-like periplasmic core domain yknZ - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD AFLMLIMI_01316 543734.LCABL_31130 2.9e-160 449.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HFUH@91061|Bacilli,3F4CA@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_01317 543734.LCABL_31120 6.14e-238 656.0 COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,3F5MV@33958|Lactobacillaceae 91061|Bacilli M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family hlyD3 - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 AFLMLIMI_01318 568703.LGG_02916 6.72e-19 78.6 2BZTI@1|root,302JZ@2|Bacteria,1U8EV@1239|Firmicutes,4IICR@91061|Bacilli,3FAWN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01319 568703.LGG_02915 5.93e-59 181.0 29PY5@1|root,30AWK@2|Bacteria,1U774@1239|Firmicutes,4IH1Y@91061|Bacilli,3F926@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01320 543734.LCABL_31080 1.29e-190 528.0 COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,3F49K@33958|Lactobacillaceae 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 AFLMLIMI_01321 543734.LCABL_31070 2.05e-168 470.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli,3F3NR@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso AFLMLIMI_01322 543734.LCABL_31060 0.0 1160.0 COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,3F52S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit mtlA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIC,PTS_IIB AFLMLIMI_01323 543734.LCABL_31050 0.0 1293.0 COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HABH@91061|Bacilli,3F561@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain mtlR - - ko:K03483 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB AFLMLIMI_01324 543734.LCABL_31040 9.2e-101 292.0 COG4668@1|root,COG4668@2|Bacteria,1V77P@1239|Firmicutes,4HIM2@91061|Bacilli,3F6EP@33958|Lactobacillaceae 91061|Bacilli G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane mtlF GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.197 ko:K02798 ko00051,ko02060,map00051,map02060 M00274 R02704 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5 - - PTS_EIIA_2 AFLMLIMI_01325 543734.LCABL_31030 1.68e-275 753.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,3F448@33958|Lactobacillaceae 91061|Bacilli C mannitol-1-phosphate 5-dehydrogenase activity mtlD GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616 1.1.1.17 ko:K00009 ko00051,map00051 - R02703 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C AFLMLIMI_01326 543734.LCABL_31020 6.18e-238 653.0 COG0657@1|root,COG0657@2|Bacteria,1V2AW@1239|Firmicutes,4HU2V@91061|Bacilli,3F3N7@33958|Lactobacillaceae 91061|Bacilli I Carboxylesterase family lipA - - - - - - - - - - - Abhydrolase_3 AFLMLIMI_01327 543734.LCABL_31010 2.32e-233 640.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,3F43H@33958|Lactobacillaceae 91061|Bacilli D Alpha beta - - - ko:K06889 - - - - ko00000 - - - DLH,FSH1,Hydrolase_4 AFLMLIMI_01328 543734.LCABL_31000 1.87e-217 600.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3V8@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N AFLMLIMI_01330 1423816.BACQ01000031_gene1258 1.92e-149 426.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain - - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD AFLMLIMI_01331 1293597.BN147_01560 2.64e-51 168.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 AFLMLIMI_01332 1423816.BACQ01000031_gene1259 5.55e-285 785.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system - - - - - - - - - - - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AFLMLIMI_01333 543734.LCABL_30770 6.76e-217 599.0 COG0826@1|root,COG0826@2|Bacteria,1TPCZ@1239|Firmicutes,4HC7A@91061|Bacilli,3F4I6@33958|Lactobacillaceae 91061|Bacilli O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity - - - - - - - - - - - - - AFLMLIMI_01334 543734.LCABL_30760 1.11e-284 781.0 COG0531@1|root,COG0531@2|Bacteria,1VTJD@1239|Firmicutes,4HTEM@91061|Bacilli,3FCAK@33958|Lactobacillaceae 91061|Bacilli E Amino acid permease yagE - - - - - - - - - - - AA_permease_2 AFLMLIMI_01335 543734.LCABL_30750 1.46e-82 244.0 29NYR@1|root,309WU@2|Bacteria,1U5V4@1239|Firmicutes,4IFIS@91061|Bacilli,3F6J0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01338 543734.LCABL_30740 7.28e-122 347.0 COG4283@1|root,COG4283@2|Bacteria,1TSF1@1239|Firmicutes,4HHG3@91061|Bacilli,3F6U6@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1706) M1-431 - - - - - - - - - - - DUF1706 AFLMLIMI_01339 543734.LCABL_30730 1.56e-194 540.0 COG2084@1|root,COG2084@2|Bacteria,1U5HC@1239|Firmicutes,4IF86@91061|Bacilli,3F5Y9@33958|Lactobacillaceae 91061|Bacilli I NAD binding domain of 6-phosphogluconate dehydrogenase - - - - - - - - - - - - NAD_binding_2 AFLMLIMI_01340 543734.LCABL_30720 1.81e-156 439.0 COG4565@1|root,COG4565@2|Bacteria,1V3PK@1239|Firmicutes,4HGXB@91061|Bacilli,3F702@33958|Lactobacillaceae 91061|Bacilli KT cheY-homologous receiver domain malR - - ko:K02475,ko:K11615 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_11,Response_reg AFLMLIMI_01341 543734.LCABL_30710 0.0 993.0 COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,3F62P@33958|Lactobacillaceae 91061|Bacilli T Single cache domain 3 dpiB - 2.7.13.3 ko:K02476,ko:K11614 ko02020,map02020 M00490 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 AFLMLIMI_01342 543734.LCABL_30700 4.43e-291 798.0 COG3493@1|root,COG3493@2|Bacteria,1TR97@1239|Firmicutes,4HBS8@91061|Bacilli,3F61N@33958|Lactobacillaceae 91061|Bacilli C 2-hydroxycarboxylate transporter family malP - - ko:K11616 ko02020,map02020 - - - ko00000,ko00001 2.A.24.2 - - 2HCT AFLMLIMI_01343 543734.LCABL_30690 3.65e-272 746.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,3F4GN@33958|Lactobacillaceae 91061|Bacilli C Malic enzyme, NAD binding domain mae - 1.1.1.38 ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 - R00214 RC00105 ko00000,ko00001,ko01000 - - - Malic_M,malic AFLMLIMI_01344 568703.LGG_02874 8.99e-63 195.0 28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,4HMY0@91061|Bacilli,3F6EY@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2992) yjdF3 - - - - - - - - - - - DUF2992 AFLMLIMI_01345 543734.LCABL_30660 1e-147 414.0 COG4430@1|root,COG4430@2|Bacteria,1VCMU@1239|Firmicutes,4HN16@91061|Bacilli,3F68B@33958|Lactobacillaceae 91061|Bacilli S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA AFLMLIMI_01346 543734.LCABL_30650 0.0 887.0 COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,3FBTC@33958|Lactobacillaceae 91061|Bacilli E Fumarase C C-terminus aspA - 4.3.1.1 ko:K01744 ko00250,ko01100,map00250,map01100 - R00490 RC00316,RC02799 ko00000,ko00001,ko01000 - - - FumaraseC_C,Lyase_1 AFLMLIMI_01347 543734.LCABL_30640 3.03e-186 518.0 COG0561@1|root,COG0561@2|Bacteria,1UYU8@1239|Firmicutes,4HE0K@91061|Bacilli,3F3ZW@33958|Lactobacillaceae 91061|Bacilli G Sucrose-6F-phosphate phosphohydrolase - - 3.1.3.102,3.1.3.104,3.1.3.23 ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R00804,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 AFLMLIMI_01348 543734.LCABL_30630 1.34e-126 363.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HGH2@91061|Bacilli,3FBEM@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase thgA3 - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac AFLMLIMI_01349 543734.LCABL_30620 4.08e-271 741.0 COG0438@1|root,COG0438@2|Bacteria,1TPHK@1239|Firmicutes,4HAXV@91061|Bacilli,3F5EZ@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 AFLMLIMI_01350 543734.LCABL_30610 0.0 1106.0 COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,3F5PB@33958|Lactobacillaceae 91061|Bacilli E Transglutaminase/protease-like homologues yebA - - - - - - - - - - - DUF4129,Transglut_core AFLMLIMI_01351 543734.LCABL_30590 1.06e-235 648.0 COG1721@1|root,COG1721@2|Bacteria,1VNZZ@1239|Firmicutes,4IGYV@91061|Bacilli,3F8YE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 AFLMLIMI_01352 1423816.BACQ01000031_gene1278 1.49e-181 510.0 COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,4HA0T@91061|Bacilli,3F59F@33958|Lactobacillaceae 91061|Bacilli S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 AFLMLIMI_01353 543734.LCABL_30560 2.22e-137 389.0 COG1300@1|root,COG1300@2|Bacteria,1VFG7@1239|Firmicutes,4IRI6@91061|Bacilli,3F7WH@33958|Lactobacillaceae 91061|Bacilli S Stage II sporulation protein M - - - ko:K06384 - - - - ko00000 - - - SpoIIM AFLMLIMI_01354 543734.LCABL_30550 9.37e-129 365.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 AFLMLIMI_01355 543734.LCABL_30540 0.0 927.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 AFLMLIMI_01356 543734.LCABL_30530 0.0 915.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli,3F4HA@33958|Lactobacillaceae 91061|Bacilli P ABC transporter glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 AFLMLIMI_01357 543734.LCABL_30520 1.09e-170 477.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AFLMLIMI_01358 543734.LCABL_30510 3.22e-214 590.0 COG3001@1|root,COG3001@2|Bacteria,1U79A@1239|Firmicutes,4HAZS@91061|Bacilli,3F3RK@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase enzyme family - - - - - - - - - - - - Fructosamin_kin AFLMLIMI_01359 543734.LCABL_30500 7.76e-186 516.0 COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,4HBQT@91061|Bacilli,3F8H5@33958|Lactobacillaceae 91061|Bacilli S AAA ATPase domain - - - - - - - - - - - - AAA_15,AAA_21,AAA_23 AFLMLIMI_01360 543734.LCABL_30490 0.0 991.0 COG3428@1|root,COG3428@2|Bacteria,1TSRJ@1239|Firmicutes,4HB8P@91061|Bacilli,3F3VB@33958|Lactobacillaceae 91061|Bacilli S Bacterial PH domain ydbT - - ko:K08981 - - - - ko00000 - - - bPH_2 AFLMLIMI_01361 543734.LCABL_30480 8.68e-106 305.0 COG3402@1|root,COG3402@2|Bacteria,1VFTS@1239|Firmicutes,4HGMB@91061|Bacilli,3F6GM@33958|Lactobacillaceae 91061|Bacilli S Bacterial PH domain ydbS - - ko:K09167 - - - - ko00000 - - - bPH_2 AFLMLIMI_01362 543734.LCABL_30470 8.12e-69 208.0 298U1@1|root,2ZVY8@2|Bacteria,1W3JF@1239|Firmicutes,4I1SS@91061|Bacilli,3F7JE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01363 1423732.BALS01000133_gene400 5.96e-53 168.0 COG4918@1|root,COG4918@2|Bacteria,1U783@1239|Firmicutes,4IH2X@91061|Bacilli,3F93I@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn AFLMLIMI_01364 543734.LCABL_30440 1.33e-166 466.0 COG5523@1|root,COG5523@2|Bacteria,1VCPB@1239|Firmicutes,4HN1D@91061|Bacilli,3F69G@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF975) - - - - - - - - - - - - DUF975 AFLMLIMI_01365 543734.LCABL_30430 1.21e-304 830.0 COG1653@1|root,COG1653@2|Bacteria,1TR68@1239|Firmicutes,4HX7S@91061|Bacilli 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 AFLMLIMI_01366 568703.LGG_02850 3.99e-41 136.0 2AHQJ@1|root,3182T@2|Bacteria,1U7RB@1239|Firmicutes,4IHNN@91061|Bacilli,3FA24@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01367 543734.LCABL_30410 3.81e-172 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran AFLMLIMI_01368 543734.LCABL_30400 0.0 1005.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 AFLMLIMI_01370 543734.LCABL_30380 1.77e-203 563.0 COG1396@1|root,COG1396@2|Bacteria,1VD8E@1239|Firmicutes,4HMD2@91061|Bacilli,3F3QV@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins ywdE - - ko:K20375 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 AFLMLIMI_01371 543734.LCABL_30370 2.29e-190 530.0 COG1396@1|root,COG1396@2|Bacteria,1W2GY@1239|Firmicutes,4IGZ7@91061|Bacilli,3F8YW@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AFLMLIMI_01372 543734.LCABL_30360 9.91e-241 662.0 COG1396@1|root,COG1396@2|Bacteria,1V9XM@1239|Firmicutes,4HJUU@91061|Bacilli,3F79A@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 AFLMLIMI_01373 543734.LCABL_30350 1.09e-275 757.0 COG0477@1|root,COG2814@2|Bacteria,1UM0A@1239|Firmicutes,4ITNK@91061|Bacilli 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 AFLMLIMI_01374 543734.LCABL_30340 3.4e-229 631.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli,3F4PU@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb AFLMLIMI_01375 543734.LCABL_30330 6.11e-169 474.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli,3F3V5@33958|Lactobacillaceae 91061|Bacilli G PTS system manM - - ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277,M00278 R02630,R04076,R08366 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3,4.A.6.1.4 - - EII-Sor AFLMLIMI_01376 543734.LCABL_30320 5.31e-211 583.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli,3F3KR@33958|Lactobacillaceae 91061|Bacilli G system, mannose fructose sorbose family IID component manN - - ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276,M00278 R02630,R04076 RC00017,RC01069,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.3 - - EIID-AGA AFLMLIMI_01377 543734.LCABL_30310 1.08e-84 249.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,4HIMF@91061|Bacilli,3F719@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF956) manO - - - - - - - - - - - DUF956 AFLMLIMI_01378 543734.LCABL_30300 2.11e-220 608.0 COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,3F40K@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase iolS - - ko:K06607 - - - - ko00000,ko01000 - - - Aldo_ket_red AFLMLIMI_01379 543734.LCABL_30290 2.67e-272 746.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli,3F52B@33958|Lactobacillaceae 91061|Bacilli P Transporter, major facilitator family protein yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 AFLMLIMI_01380 543734.LCABL_30280 0.0 904.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4HBXJ@91061|Bacilli,3F5DA@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_3 AFLMLIMI_01381 543734.LCABL_30270 3.32e-148 417.0 COG1335@1|root,COG1335@2|Bacteria,1V7WN@1239|Firmicutes,4HIYX@91061|Bacilli,3F4WV@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family ycaC - - - - - - - - - - - Isochorismatase AFLMLIMI_01382 543734.LCABL_30260 2.61e-117 336.0 COG4639@1|root,COG4639@2|Bacteria,1V2CI@1239|Firmicutes,4HGAU@91061|Bacilli,3FBXH@33958|Lactobacillaceae 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_33 AFLMLIMI_01383 543734.LCABL_30250 1.84e-110 317.0 COG1051@1|root,COG1051@2|Bacteria,1V5NQ@1239|Firmicutes,4HH6Z@91061|Bacilli,3F674@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX AFLMLIMI_01384 543734.LCABL_30240 3.03e-139 392.0 COG1670@1|root,COG1670@2|Bacteria,1V3W1@1239|Firmicutes,4HH6A@91061|Bacilli,3F6G6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yokL3 - - - - - - - - - - - Acetyltransf_3 AFLMLIMI_01385 543734.LCABL_30230 8.36e-72 216.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3F6Z5@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA AFLMLIMI_01386 543734.LCABL_30220 5.86e-68 206.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F6GU@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit pts20B - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB AFLMLIMI_01387 543734.LCABL_30210 1.97e-168 470.0 COG2188@1|root,COG2188@2|Bacteria,1V54P@1239|Firmicutes,4IPPI@91061|Bacilli,3F5X0@33958|Lactobacillaceae 91061|Bacilli K UTRA gntR - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_01388 543734.LCABL_30200 0.0 879.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_01389 543734.LCABL_30190 9.09e-97 281.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F69F@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 AFLMLIMI_01390 543734.LCABL_30180 4.59e-271 741.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) ybhE - - ko:K09963 - - - - ko00000 - - - DUF871 AFLMLIMI_01391 543734.LCABL_30170 0.0 910.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,3F4PF@33958|Lactobacillaceae 91061|Bacilli E argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 AFLMLIMI_01392 543734.LCABL_30160 1.63e-298 813.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,3F46X@33958|Lactobacillaceae 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth AFLMLIMI_01393 543734.LCABL_30150 0.0 891.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease arpJ - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - iSB619.SA_RS09465 BPD_transp_1,SBP_bac_3 AFLMLIMI_01394 543734.LCABL_30140 2.49e-156 439.0 COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli,3FBGC@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase family - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 AFLMLIMI_01395 543734.LCABL_30130 3.03e-168 470.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,3F4FB@33958|Lactobacillaceae 91061|Bacilli K response regulator yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C AFLMLIMI_01396 543734.LCABL_30120 0.0 1214.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,3F45G@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 AFLMLIMI_01397 543734.LCABL_30110 0.0 908.0 COG4863@1|root,COG4863@2|Bacteria,1V32Y@1239|Firmicutes,4HG2Q@91061|Bacilli,3F4HR@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycH - - - - - - - - - - - YycH AFLMLIMI_01398 543734.LCABL_30100 1.05e-182 509.0 COG4853@1|root,COG4853@2|Bacteria,1V1FW@1239|Firmicutes,4HFWZ@91061|Bacilli,3F3PV@33958|Lactobacillaceae 91061|Bacilli S YycH protein yycI - - - - - - - - - - - YycI AFLMLIMI_01399 543734.LCABL_30090 4.32e-196 543.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,3F3S4@33958|Lactobacillaceae 91061|Bacilli S domain protein vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 AFLMLIMI_01400 543734.LCABL_30080 1.7e-284 781.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli,3F45X@33958|Lactobacillaceae 91061|Bacilli O serine protease htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 AFLMLIMI_01401 543734.LCABL_30070 2.35e-92 270.0 2F916@1|root,341CT@2|Bacteria,1VY7K@1239|Firmicutes,4HX4B@91061|Bacilli,3F70S@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn AFLMLIMI_01402 543734.LCABL_30060 1.8e-99 288.0 COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HPDH@91061|Bacilli,3F7DR@33958|Lactobacillaceae 91061|Bacilli O Belongs to the small heat shock protein (HSP20) family hsp3 - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 AFLMLIMI_01403 543734.LCABL_30050 0.0 1122.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,3F4JI@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase cadA - - - - - - - - - - - E1-E2_ATPase,Hydrolase AFLMLIMI_01404 568703.LGG_02802 2.5e-134 397.0 29Q2V@1|root,30B1G@2|Bacteria,1U7DH@1239|Firmicutes,4IH9F@91061|Bacilli,3F9FB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01405 543734.LCABL_30030 0.0 1034.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AFLMLIMI_01406 543734.LCABL_30020 0.0 892.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,3F541@33958|Lactobacillaceae 91061|Bacilli E Peptidase dimerisation domain dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AFLMLIMI_01407 568703.LGG_02799 3.05e-91 278.0 29Q2V@1|root,30B3P@2|Bacteria,1U7H9@1239|Firmicutes,4IHDU@91061|Bacilli,3F9PB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01408 543734.LCABL_30000 6.32e-253 695.0 COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,4HEW7@91061|Bacilli,3F4CJ@33958|Lactobacillaceae 91061|Bacilli P Citrate transporter ysdE - - - - - - - - - - - CitMHS AFLMLIMI_01409 543734.LCABL_29990 1.01e-105 305.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli,3F3YX@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase AFLMLIMI_01410 543734.LCABL_29950 4.68e-99 288.0 COG0454@1|root,COG0454@2|Bacteria,1UHUT@1239|Firmicutes,4HSN0@91061|Bacilli,3FBXG@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_10 AFLMLIMI_01411 543734.LCABL_29940 2.33e-100 291.0 COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,4HIRW@91061|Bacilli,3F7FI@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain yiaC - - ko:K03826 - - - - ko00000,ko01000 - - - Acetyltransf_10,Acetyltransf_7 AFLMLIMI_01412 568703.LGG_02795 1.02e-78 242.0 2DYM8@1|root,34AAZ@2|Bacteria,1VZP6@1239|Firmicutes,4HZAB@91061|Bacilli,3F99W@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01413 1231336.L248_1998 3.06e-157 451.0 COG0451@1|root,COG0451@2|Bacteria,1UEMD@1239|Firmicutes,4HDN7@91061|Bacilli,3F5S3@33958|Lactobacillaceae 91061|Bacilli GM Male sterility protein - - - - - - - - - - - - 3Beta_HSD,Epimerase AFLMLIMI_01414 1136177.KCA1_2468 1.6e-55 177.0 COG0789@1|root,COG0789@2|Bacteria,1V3QI@1239|Firmicutes,4IPUS@91061|Bacilli 91061|Bacilli K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 AFLMLIMI_01415 543734.LCABL_29930 7.95e-103 299.0 COG0454@1|root,COG0456@2|Bacteria,1V8AJ@1239|Firmicutes,4HPGU@91061|Bacilli,3F6YY@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 AFLMLIMI_01416 543734.LCABL_29910 1.33e-178 497.0 COG2365@1|root,COG2365@2|Bacteria,1V6Q5@1239|Firmicutes,4HJKY@91061|Bacilli,3F5X1@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp1 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 AFLMLIMI_01417 543734.LCABL_29900 1.02e-236 652.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,3F4EJ@33958|Lactobacillaceae 91061|Bacilli C nadph quinone reductase - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 AFLMLIMI_01418 543734.LCABL_29890 5.71e-121 345.0 COG0241@1|root,COG0241@2|Bacteria,1V6DW@1239|Firmicutes,4HJ23@91061|Bacilli 91061|Bacilli E HAD-hyrolase-like - - - - - - - - - - - - Hydrolase_like AFLMLIMI_01419 543734.LCABL_29880 9.24e-119 339.0 COG0454@1|root,COG0456@2|Bacteria,1VEEJ@1239|Firmicutes,4HP6M@91061|Bacilli,3FBDP@33958|Lactobacillaceae 91061|Bacilli K FR47-like protein yfbM - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 AFLMLIMI_01420 543734.LCABL_29870 6.1e-171 477.0 COG3393@1|root,COG3393@2|Bacteria,1TRN7@1239|Firmicutes,4HWMG@91061|Bacilli,3F84U@33958|Lactobacillaceae 91061|Bacilli S -acetyltransferase - - - - - - - - - - - - - AFLMLIMI_01421 543734.LCABL_29820 2.16e-68 207.0 COG2076@1|root,COG2076@2|Bacteria,1VEZX@1239|Firmicutes,4HKXB@91061|Bacilli,3F7D6@33958|Lactobacillaceae 91061|Bacilli U Multidrug resistance protein sugE - - ko:K11741 - - - - ko00000,ko02000 2.A.7.1 - - Multi_Drug_Res AFLMLIMI_01422 543734.LCABL_29810 5.6e-133 377.0 COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HIIG@91061|Bacilli,3F4S0@33958|Lactobacillaceae 91061|Bacilli Q Methyltransferase - - - - - - - - - - - - Methyltransf_11 AFLMLIMI_01423 543734.LCABL_29790 6.53e-220 607.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,3F4FC@33958|Lactobacillaceae 91061|Bacilli S DHHA1 domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 AFLMLIMI_01424 543734.LCABL_29780 1.76e-258 708.0 COG3568@1|root,COG3568@2|Bacteria,1U5BI@1239|Firmicutes,4HE49@91061|Bacilli,3F57I@33958|Lactobacillaceae 91061|Bacilli S endonuclease exonuclease phosphatase family protein - - - - - - - - - - - - Exo_endo_phos AFLMLIMI_01425 543734.LCABL_29770 8.76e-177 495.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4IQM3@91061|Bacilli,3F5ZV@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component XK27_08455 - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_01426 543734.LCABL_29760 1.56e-192 536.0 COG3716@1|root,COG3716@2|Bacteria,1UZG2@1239|Firmicutes,4IQM5@91061|Bacilli,3F5FR@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA AFLMLIMI_01427 543734.LCABL_29750 1.67e-105 305.0 COG3444@1|root,COG3444@2|Bacteria,1V58C@1239|Firmicutes,4HJ9Y@91061|Bacilli,3F79W@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb AFLMLIMI_01428 543734.LCABL_29740 1.58e-211 585.0 COG1737@1|root,COG1737@2|Bacteria,1V26Y@1239|Firmicutes,4IQVW@91061|Bacilli,3FBJG@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS AFLMLIMI_01429 543734.LCABL_29730 1.43e-197 549.0 COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4HBWP@91061|Bacilli,3F4T1@33958|Lactobacillaceae 91061|Bacilli G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate murQ - 4.2.1.126 ko:K07106 ko00520,ko01100,map00520,map01100 - R08555 RC00397,RC00746 ko00000,ko00001,ko01000 - - - SIS,SIS_2 AFLMLIMI_01430 543734.LCABL_29720 4.42e-249 683.0 COG1680@1|root,COG1680@2|Bacteria,1U828@1239|Firmicutes,4HA0Q@91061|Bacilli,3F4K3@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase AFLMLIMI_01431 543734.LCABL_29710 3.21e-245 674.0 COG4948@1|root,COG4948@2|Bacteria,1TQMS@1239|Firmicutes,4HCY5@91061|Bacilli,3F4XQ@33958|Lactobacillaceae 91061|Bacilli M Belongs to the mandelate racemase muconate lactonizing enzyme family ykfB - 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N AFLMLIMI_01432 543734.LCABL_29700 2.92e-187 520.0 COG2367@1|root,COG2367@2|Bacteria,1VAJP@1239|Firmicutes 1239|Firmicutes V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 AFLMLIMI_01433 543734.LCABL_29690 5.44e-174 485.0 COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,1UZ4E@1239|Firmicutes,4IPMJ@91061|Bacilli,3FBCZ@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX AFLMLIMI_01434 543734.LCABL_29680 7.69e-139 391.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli,3F41F@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family pncA - - - - - - - - - - - Isochorismatase AFLMLIMI_01435 543734.LCABL_29670 0.0 924.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP nadC2 - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase AFLMLIMI_01436 543734.LCABL_29660 6.03e-270 738.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HA50@91061|Bacilli,3FC3B@33958|Lactobacillaceae 91061|Bacilli E Belongs to the ABC transporter superfamily ugpC - 3.6.3.20 ko:K05816,ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1,3.A.1.1.3 - - ABC_tran,TOBE_2 AFLMLIMI_01437 543734.LCABL_29650 2.62e-210 582.0 COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HCD0@91061|Bacilli,3F464@33958|Lactobacillaceae 91061|Bacilli P ABC-type sugar transport systems, permease components - - - ko:K05814 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 AFLMLIMI_01438 543734.LCABL_29640 2.92e-192 533.0 COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,4HB8C@91061|Bacilli,3F4Q5@33958|Lactobacillaceae 91061|Bacilli G ABC transporter permease ugpE - - ko:K05815 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 AFLMLIMI_01439 543734.LCABL_29630 0.0 885.0 COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,4HARC@91061|Bacilli,3FC76@33958|Lactobacillaceae 91061|Bacilli G Bacterial extracellular solute-binding protein ugpB - - ko:K05813 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - SBP_bac_8 AFLMLIMI_01440 543734.LCABL_29620 1.36e-91 268.0 COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,4HH49@91061|Bacilli,3F6GQ@33958|Lactobacillaceae 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family arsC GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008794,GO:0016491,GO:0030611,GO:0030613,GO:0030614,GO:0042221,GO:0046685,GO:0050896,GO:0055114 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - LMWPc AFLMLIMI_01441 568703.LGG_02766 1.09e-154 435.0 COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3F4E3@33958|Lactobacillaceae 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ1 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD AFLMLIMI_01442 543734.LCABL_29590 1.48e-122 350.0 COG1476@1|root,COG1476@2|Bacteria,1VDCA@1239|Firmicutes,4HN0T@91061|Bacilli,3F7ZF@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - DUF1700,HTH_3,HTH_31 AFLMLIMI_01444 543734.LCABL_29570 5.32e-73 218.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - ps105 - - - - - - - - - - - - AFLMLIMI_01445 568703.LGG_02642 1.29e-47 154.0 2E9Y3@1|root,3343R@2|Bacteria,1VFF0@1239|Firmicutes,4HPUY@91061|Bacilli,3F8BC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01446 543734.LCABL_29560 6.74e-117 334.0 COG1335@1|root,COG1335@2|Bacteria,1VF7P@1239|Firmicutes,4HQSB@91061|Bacilli,3FC9Z@33958|Lactobacillaceae 91061|Bacilli Q Isochorismatase family yveA - - - - - - - - - - - Isochorismatase AFLMLIMI_01447 543734.LCABL_29550 1.53e-113 326.0 COG0454@1|root,COG0454@2|Bacteria,1UHNV@1239|Firmicutes,4IS4R@91061|Bacilli,3F7IJ@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - - - - - - - - - - Acetyltransf_1 AFLMLIMI_01448 543734.LCABL_29540 0.0 995.0 COG0477@1|root,COG2814@2|Bacteria,1VRVX@1239|Firmicutes,4HV95@91061|Bacilli,3F4T2@33958|Lactobacillaceae 91061|Bacilli U the major facilitator superfamily chaT1 - - ko:K03446 - M00701 - - ko00000,ko00002,ko02000 2.A.1.3 - - MFS_1 AFLMLIMI_01449 543734.LCABL_29530 2.16e-132 375.0 COG1695@1|root,COG1695@2|Bacteria,1VEN3@1239|Firmicutes,4HS7A@91061|Bacilli,3F6IE@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family laaE - - - - - - - - - - - PadR AFLMLIMI_01450 543734.LCABL_29520 2.18e-112 323.0 COG1247@1|root,COG1247@2|Bacteria,1UIWB@1239|Firmicutes,4ISUG@91061|Bacilli 91061|Bacilli M Acetyltransferase (GNAT) domain - - - ko:K03828 - - - - ko00000,ko01000 - - - Acetyltransf_1 AFLMLIMI_01451 543734.LCABL_29340 9.84e-264 720.0 COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,4HTW2@91061|Bacilli,3F4ZS@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos AFLMLIMI_01452 543734.LCABL_29330 1.37e-271 745.0 COG0477@1|root,COG2814@2|Bacteria,1TQZ7@1239|Firmicutes,4HERG@91061|Bacilli,3F54C@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein - - - - - - - - - - - - MFS_1 AFLMLIMI_01453 543734.LCABL_29320 0.0 1048.0 COG0436@1|root,COG0436@2|Bacteria,1TQP8@1239|Firmicutes,4HECY@91061|Bacilli 91061|Bacilli E Aminotransferase - - 4.1.1.12 ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 - R00397,R00863 RC00282,RC00399,RC00400 ko00000,ko00001,ko01000 - - - Aminotran_1_2 AFLMLIMI_01454 543734.LCABL_29310 3.68e-170 475.0 COG2188@1|root,COG2188@2|Bacteria,1V338@1239|Firmicutes,4HGUM@91061|Bacilli,3F682@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_01455 543734.LCABL_29300 0.0 884.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HBQA@91061|Bacilli,3F5AY@33958|Lactobacillaceae 91061|Bacilli E Peptidase family M20/M25/M40 - - - - - - - - - - - - Peptidase_M20 AFLMLIMI_01456 543734.LCABL_29290 5.03e-229 630.0 COG1446@1|root,COG1446@2|Bacteria,1TSWB@1239|Firmicutes,4HED0@91061|Bacilli,3F3SI@33958|Lactobacillaceae 91061|Bacilli E Asparaginase asnA2 - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase_2 AFLMLIMI_01457 543734.LCABL_29280 1.2e-205 570.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli,3F3ZI@33958|Lactobacillaceae 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK AFLMLIMI_01458 208596.CAR_c23420 2.91e-17 85.9 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HB6A@91061|Bacilli,27HGM@186828|Carnobacteriaceae 91061|Bacilli GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 manR - - ko:K02538,ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB AFLMLIMI_01459 913848.AELK01000268_gene1754 1.92e-63 198.0 COG1762@1|root,COG1762@2|Bacteria,1V7JV@1239|Firmicutes,4HJ0E@91061|Bacilli,3F73T@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 frvA - 2.7.1.202 ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2 AFLMLIMI_01460 913848.AELK01000268_gene1753 1.03e-50 162.0 COG1445@1|root,COG1445@2|Bacteria,1VASC@1239|Firmicutes,4HKYF@91061|Bacilli,3F7K8@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.202 ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_IIB AFLMLIMI_01461 913848.AELK01000268_gene1752 5.32e-196 550.0 COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,4H9XS@91061|Bacilli,3F52Q@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase System - - - - - - - - - - - - PTS_EIIC AFLMLIMI_01462 543734.LCABL_29150 4.59e-275 750.0 COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,4HBNW@91061|Bacilli,3F58F@33958|Lactobacillaceae 91061|Bacilli S Beta-lactamase superfamily domain ulaG - - ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 M00550 R07677 RC02793 ko00000,ko00001,ko00002,ko01000 - - - Lactamase_B_2,Lactamase_B_3 AFLMLIMI_01463 543734.LCABL_29140 4.89e-105 303.0 COG1762@1|root,COG1762@2|Bacteria,1V892@1239|Firmicutes,4IQ69@91061|Bacilli,3F6HA@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - 2.7.1.194 ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_EIIA_2 AFLMLIMI_01464 543734.LCABL_29130 0.0 978.0 COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,4HB7T@91061|Bacilli,3FC40@33958|Lactobacillaceae 91061|Bacilli S PTS system sugar-specific permease component sgaT - - ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.7.1 - - EIIC-GAT AFLMLIMI_01465 543734.LCABL_29120 3.36e-61 188.0 COG3414@1|root,COG3414@2|Bacteria,1VHNP@1239|Firmicutes,4IR7Z@91061|Bacilli,3F78S@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit sgaB - 2.7.1.194 ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 M00283,M00550 R07671 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.7.1 - - PTS_IIB AFLMLIMI_01466 543734.LCABL_29110 6.14e-147 414.0 COG0269@1|root,COG0269@2|Bacteria,1TSHP@1239|Firmicutes,4HCA8@91061|Bacilli,3F3YT@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family ulaD - 4.1.1.85,4.1.2.43 ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 M00345,M00550,M00580 R05338,R07125 RC00421,RC00422,RC01721 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AFLMLIMI_01467 543734.LCABL_29100 8.64e-178 496.0 COG1349@1|root,COG1349@2|Bacteria,1UYQX@1239|Firmicutes,4HMB5@91061|Bacilli,3F6Z8@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR AFLMLIMI_01468 543734.LCABL_29090 1.26e-211 584.0 COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,4HBBU@91061|Bacilli,3F5GZ@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase-like TIM barrel sga - 5.1.3.22 ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R03244 RC00540 ko00000,ko00001,ko00002,ko01000 - - - AP_endonuc_2 AFLMLIMI_01469 543734.LCABL_29080 1.45e-193 537.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HCEA@91061|Bacilli,3F4G9@33958|Lactobacillaceae 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase - - - - - - - - - - - - Hydrolase_3 AFLMLIMI_01470 543734.LCABL_29070 1.51e-175 489.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,4H9W0@91061|Bacilli,3F43P@33958|Lactobacillaceae 91061|Bacilli G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source araD GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.1.3.4 ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 M00550 R05850 RC01479 ko00000,ko00001,ko00002,ko01000 - - - Aldolase_II AFLMLIMI_01471 543734.LCABL_29060 4.13e-185 515.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli,3F4CR@33958|Lactobacillaceae 91061|Bacilli IQ NAD dependent epimerase/dehydratase family srlD2 - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short AFLMLIMI_01472 543734.LCABL_29050 0.0 1207.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UZ36@1239|Firmicutes,4HDUK@91061|Bacilli,3F5E0@33958|Lactobacillaceae 91061|Bacilli GKT Mga helix-turn-helix domain srlM - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 AFLMLIMI_01473 543734.LCABL_29040 2.63e-115 330.0 COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,4HP9S@91061|Bacilli,3F7F5@33958|Lactobacillaceae 91061|Bacilli K Glucitol operon activator protein (GutM) srlM1 - - - - - - - - - - - GutM AFLMLIMI_01474 543734.LCABL_29030 5.81e-131 372.0 COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,4HEHX@91061|Bacilli,3F445@33958|Lactobacillaceae 91061|Bacilli G PTS system enzyme II sorbitol-specific factor srlA - - ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 - - EII-GUT AFLMLIMI_01475 543734.LCABL_29020 2.76e-250 689.0 COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,4HA7E@91061|Bacilli,3F5AP@33958|Lactobacillaceae 91061|Bacilli G Sorbitol phosphotransferase enzyme II N-terminus srlE - 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - EIIBC-GUT_C,EIIBC-GUT_N AFLMLIMI_01476 543734.LCABL_29010 2.24e-84 249.0 COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,4HPTF@91061|Bacilli,3F7KY@33958|Lactobacillaceae 91061|Bacilli G PTS system glucitol/sorbitol-specific IIA component - - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA AFLMLIMI_01477 543734.LCABL_29000 8.74e-161 450.0 COG0176@1|root,COG0176@2|Bacteria,1V4IX@1239|Firmicutes,4HJYI@91061|Bacilli,3FCEA@33958|Lactobacillaceae 91061|Bacilli H Pfam:Transaldolase - - - - - - - - - - - - TAL_FSA AFLMLIMI_01478 543734.LCABL_28990 0.0 1187.0 COG3711@1|root,COG3711@2|Bacteria,1U0UU@1239|Firmicutes,4HJZ1@91061|Bacilli,3F5NV@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - HTH_11,PRD AFLMLIMI_01479 543734.LCABL_28980 6.08e-73 219.0 2CG0N@1|root,32S2X@2|Bacteria,1VI2Z@1239|Firmicutes,4HQX6@91061|Bacilli,3F8H0@33958|Lactobacillaceae 91061|Bacilli S PRD domain - - - - - - - - - - - - PRD AFLMLIMI_01480 543734.LCABL_28970 8.65e-81 239.0 292C3@1|root,2ZPWH@2|Bacteria,1V7VZ@1239|Firmicutes,4HIX7@91061|Bacilli,3F6XI@33958|Lactobacillaceae 91061|Bacilli S Glycine-rich SFCGS - - - - - - - - - - - - Gly_rich_SFCGS AFLMLIMI_01481 543734.LCABL_28960 1.1e-76 229.0 2AJY2@1|root,31AM7@2|Bacteria,1VQQN@1239|Firmicutes,4IRVB@91061|Bacilli,3F93K@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4312) - - - - - - - - - - - - DUF4312 AFLMLIMI_01482 543734.LCABL_28950 4.1e-177 494.0 28HBR@1|root,2Z7NQ@2|Bacteria,1TQ2N@1239|Firmicutes,4HAZ6@91061|Bacilli,3F5N2@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4311) - - - - - - - - - - - - DUF4311 AFLMLIMI_01483 543734.LCABL_28940 3.79e-155 436.0 2CHGF@1|root,2Z7QV@2|Bacteria,1TRJJ@1239|Firmicutes,4HC0E@91061|Bacilli,3F5QZ@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4310) - - - - - - - - - - - - DUF4310 AFLMLIMI_01484 543734.LCABL_28930 8.63e-275 751.0 COG3964@1|root,COG3964@2|Bacteria,1TPXM@1239|Firmicutes,4HBNV@91061|Bacilli,3F4S7@33958|Lactobacillaceae 91061|Bacilli S Amidohydrolase family dho - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 AFLMLIMI_01485 543734.LCABL_28920 2.62e-261 716.0 COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,4HC3U@91061|Bacilli,3F4MN@33958|Lactobacillaceae 91061|Bacilli H L-seryl-tRNA selenium transferase selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - SelA AFLMLIMI_01486 543734.LCABL_28910 5.63e-177 493.0 2DBAP@1|root,2Z844@2|Bacteria,1TQX7@1239|Firmicutes,4HABQ@91061|Bacilli,3F5QS@33958|Lactobacillaceae 91061|Bacilli S KDGP aldolase - - 4.1.2.14 ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 M00061,M00631 R05605 RC00307,RC00435 ko00000,ko00001,ko00002,ko01000 - - - KDGP_aldolase AFLMLIMI_01487 543734.LCABL_28900 1.09e-254 700.0 COG0457@1|root,COG1434@1|root,COG0457@2|Bacteria,COG1434@2|Bacteria,1V0QQ@1239|Firmicutes,4I373@91061|Bacilli,3FAS6@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 AFLMLIMI_01488 1545702.LACWKB8_1633 1.39e-98 312.0 COG3711@1|root,COG3711@2|Bacteria,1TSGM@1239|Firmicutes,4HB3W@91061|Bacilli,3F482@33958|Lactobacillaceae 91061|Bacilli K PRD domain - - - ko:K02538 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB AFLMLIMI_01490 46256.BBIK01000001_gene130 1.07e-32 120.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HMCG@91061|Bacilli,4AY39@81850|Leuconostocaceae 91061|Bacilli G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) - - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 AFLMLIMI_01491 1114972.AUAW01000022_gene1261 1.28e-204 579.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HA1Q@91061|Bacilli,3F427@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component - - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT AFLMLIMI_01492 873448.STRPO_1585 1.57e-39 133.0 COG3414@1|root,COG3414@2|Bacteria,1VCNU@1239|Firmicutes,4HM3X@91061|Bacilli 91061|Bacilli G Phosphotransferase system, galactitol-specific IIB component - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB AFLMLIMI_01493 1545702.LACWKB8_1630 4.32e-123 359.0 COG0191@1|root,COG0191@2|Bacteria,1TRQY@1239|Firmicutes,4HC8E@91061|Bacilli,3FCBB@33958|Lactobacillaceae 91061|Bacilli G Fructose-bisphosphate aldolase class-II gatY - 4.1.2.13,4.1.2.40 ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01069,R01070,R01829,R02568 RC00438,RC00439,RC00603,RC00604 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase AFLMLIMI_01494 1545702.LACWKB8_1629 9.11e-97 288.0 COG0149@1|root,COG0149@2|Bacteria,1UZAR@1239|Firmicutes,4HBA2@91061|Bacilli,3F9SE@33958|Lactobacillaceae 91061|Bacilli G Triose-phosphate isomerase - - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM AFLMLIMI_01495 768486.EHR_05290 1.96e-86 258.0 COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,4HHPU@91061|Bacilli,4B1KC@81852|Enterococcaceae 91061|Bacilli S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 AFLMLIMI_01498 543734.LCABL_28880 2.57e-109 315.0 COG2190@1|root,COG2190@2|Bacteria,1VAEB@1239|Firmicutes,4HIPR@91061|Bacilli,3FC0X@33958|Lactobacillaceae 91061|Bacilli G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ptbA - 2.7.1.208 ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00271,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12,4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1 AFLMLIMI_01499 543734.LCABL_28870 3.79e-153 432.0 COG1737@1|root,COG1737@2|Bacteria,1TR75@1239|Firmicutes,4HJU7@91061|Bacilli,3F6Y6@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family - - - - - - - - - - - - HTH_6,SIS AFLMLIMI_01500 568703.LGG_01866 1.44e-167 489.0 COG3711@1|root,COG3711@2|Bacteria,1U47D@1239|Firmicutes,4IDYQ@91061|Bacilli,3F986@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga AFLMLIMI_01501 543734.LCABL_28820 7.2e-109 314.0 2DJFW@1|root,305ZW@2|Bacteria,1TYZ0@1239|Firmicutes,4HW93@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01502 543734.LCABL_28810 8.04e-140 395.0 2F49V@1|root,33X0H@2|Bacteria,1VWJ1@1239|Firmicutes,4HWUD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01504 543734.LCABL_28760 0.0 1205.0 2DVNR@1|root,33WIQ@2|Bacteria,1VVQM@1239|Firmicutes,4HWSH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01505 543734.LCABL_28750 0.0 1947.0 COG5492@1|root,COG5492@2|Bacteria,1TQ2K@1239|Firmicutes,4HBG8@91061|Bacilli,3F9RZ@33958|Lactobacillaceae 91061|Bacilli N Polysaccharide lyase family 8, N terminal alpha-helical domain hylB GO:0005575,GO:0005576 4.2.2.1 ko:K01727 - - - - ko00000,ko01000 - PL8 - Big_2,F5_F8_type_C,FIVAR,Gram_pos_anchor,Lyase_8,Lyase_8_C,Lyase_8_N,SLH,YSIRK_signal AFLMLIMI_01506 543734.LCABL_28740 0.0 1017.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,3F44V@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system, EIIB - - 2.7.1.199,2.7.1.208 ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 M00266 R02738,R04111 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.3 - - PTS_EIIB,PTS_EIIC AFLMLIMI_01507 543734.LCABL_28730 0.0 935.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9TM@91061|Bacilli,3F4W5@33958|Lactobacillaceae 91061|Bacilli G Family 4 glycosyl hydrolase C-terminal domain - - 3.2.1.122 ko:K01232 ko00500,map00500 - R00837,R00838,R06113 RC00049 ko00000,ko00001,ko01000 - GH4 - Glyco_hydro_4,Glyco_hydro_4C AFLMLIMI_01508 543734.LCABL_28720 3.97e-162 454.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F3JF@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal llrE - - - - - - - - - - - Response_reg,Trans_reg_C AFLMLIMI_01509 543734.LCABL_28710 8.98e-316 862.0 COG0642@1|root,COG2205@2|Bacteria,1VU2I@1239|Firmicutes,4HHZT@91061|Bacilli,3F475@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase kinE - - - - - - - - - - - HAMP,HATPase_c,HisKA AFLMLIMI_01510 543734.LCABL_28700 4.85e-151 425.0 COG0586@1|root,COG0586@2|Bacteria,1UZ4P@1239|Firmicutes,4HG3F@91061|Bacilli,3F4KG@33958|Lactobacillaceae 91061|Bacilli S SNARE-like domain protein - - - ko:K03975 - - - - ko00000 - - - SNARE_assoc AFLMLIMI_01511 543734.LCABL_28690 1.56e-154 434.0 COG0671@1|root,COG0671@2|Bacteria,1VY85@1239|Firmicutes,4HXM4@91061|Bacilli,3F4DD@33958|Lactobacillaceae 91061|Bacilli I phosphatase - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2,PAP2_3 AFLMLIMI_01512 543734.LCABL_28680 2.88e-220 608.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3F3X7@33958|Lactobacillaceae 91061|Bacilli M Glycosyl transferase family 2 ykoT - - - - - - - - - - - Glycos_transf_2 AFLMLIMI_01513 543734.LCABL_28670 0.0 1234.0 COG1807@1|root,COG1807@2|Bacteria,1UYWB@1239|Firmicutes,4HTZD@91061|Bacilli,3F5AG@33958|Lactobacillaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - AFLMLIMI_01514 543734.LCABL_28660 7.16e-163 456.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,3F43N@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A AFLMLIMI_01515 543734.LCABL_28650 3.71e-153 430.0 COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,3F4B1@33958|Lactobacillaceae 91061|Bacilli L DNA alkylation repair enzyme alkD - - - - - - - - - - - DNA_alkylation AFLMLIMI_01516 543734.LCABL_28640 2.27e-246 676.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,4HT5E@91061|Bacilli,3FC26@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB AFLMLIMI_01517 543734.LCABL_28630 2.82e-154 433.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase AFLMLIMI_01518 543734.LCABL_28620 6.38e-193 535.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,4HAMW@91061|Bacilli,3F4N6@33958|Lactobacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) kduD - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 AFLMLIMI_01519 543734.LCABL_28610 5.33e-209 577.0 COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,4HBJH@91061|Bacilli,3F4U4@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate kduI - 5.3.1.17 ko:K01815 ko00040,map00040 - R04383 RC00541 ko00000,ko00001,ko01000 - - - KduI AFLMLIMI_01520 543734.LCABL_28600 1.1e-179 500.0 COG1414@1|root,COG1414@2|Bacteria,1V8YE@1239|Firmicutes,4HIR8@91061|Bacilli,3F4Y3@33958|Lactobacillaceae 91061|Bacilli K Bacterial transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR AFLMLIMI_01521 543734.LCABL_28590 1.58e-203 562.0 2DBRG@1|root,2ZAKM@2|Bacteria,1UQ8F@1239|Firmicutes,4HHHY@91061|Bacilli,3F6PP@33958|Lactobacillaceae 91061|Bacilli S Psort location Cytoplasmic, score - - - - - - - - - - - - - AFLMLIMI_01522 543734.LCABL_28580 2.47e-295 804.0 COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,4HCM9@91061|Bacilli,3F5YB@33958|Lactobacillaceae 91061|Bacilli S Glycosyl Hydrolase Family 88 ugl GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0015929,GO:0016052,GO:0016787,GO:0016798,GO:0033931,GO:0043170,GO:0044238,GO:0044419,GO:0051704,GO:0052757,GO:0071704,GO:1901575 3.2.1.180 ko:K18581 - - R10867 RC00049,RC02427 ko00000,ko01000 - GH88 - Glyco_hydro_88 AFLMLIMI_01523 543734.LCABL_28570 1.72e-114 328.0 COG3444@1|root,COG3444@2|Bacteria,1V20H@1239|Firmicutes,4HGNG@91061|Bacilli,3FC7T@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - - ko:K02745 ko00052,ko02060,map00052,map02060 M00277 R08366 RC00017 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4 - - PTSIIB_sorb AFLMLIMI_01524 543734.LCABL_28560 4.62e-184 513.0 COG3715@1|root,COG3715@2|Bacteria,1TRMS@1239|Firmicutes,4HDP2@91061|Bacilli,3FC9G@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02746 ko00052,ko02060,map00052,map02060 M00277 R08366 RC00017 ko00000,ko00001,ko00002,ko02000 4.A.6.1.4 - - EII-Sor AFLMLIMI_01525 543734.LCABL_28550 8.63e-185 514.0 COG3716@1|root,COG3716@2|Bacteria,1TSQF@1239|Firmicutes,4HEP4@91061|Bacilli,3F66Y@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component agaD - - ko:K02747 ko00052,ko02060,map00052,map02060 M00277 R08366 RC00017 ko00000,ko00001,ko00002,ko02000 4.A.6.1.4 - - EIID-AGA AFLMLIMI_01526 543734.LCABL_28540 1.14e-105 305.0 COG2893@1|root,COG2893@2|Bacteria,1W0I6@1239|Firmicutes 1239|Firmicutes G PTS system fructose IIA component - - - ko:K02744 ko00052,ko02060,map00052,map02060 M00277,M00287 R08366,R08367 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1.4,4.A.6.1.5 - - EIIA-man AFLMLIMI_01528 543734.LCABL_28520 0.0 1264.0 COG5434@1|root,COG5434@2|Bacteria,1UHQG@1239|Firmicutes,4ISXY@91061|Bacilli 91061|Bacilli M Heparinase II/III N-terminus - - - - - - - - - - - - Hepar_II_III,Hepar_II_III_N AFLMLIMI_01529 1423816.BACQ01000033_gene1420 1.14e-95 293.0 2E4QH@1|root,32ZJ3@2|Bacteria,1V374@1239|Firmicutes,4I0YF@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01530 1423816.BACQ01000033_gene1421 0.0 1004.0 COG5434@1|root,COG5434@2|Bacteria,1TRWY@1239|Firmicutes,4ITNJ@91061|Bacilli,3FA55@33958|Lactobacillaceae 91061|Bacilli M Right handed beta helix region - - - - - - - - - - - - Gram_pos_anchor AFLMLIMI_01533 543734.LCABL_28460 0.0 1177.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein - - 3.2.1.10,3.2.1.20 ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199 RC00028,RC00049,RC00059,RC00077,RC00451 ko00000,ko00001,ko01000 - GH13,GH31 - Alpha-amylase,Malt_amylase_C AFLMLIMI_01534 543734.LCABL_28450 2.74e-207 572.0 COG1092@1|root,COG1092@2|Bacteria,1UM09@1239|Firmicutes,4ITNI@91061|Bacilli,3F5VI@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 AFLMLIMI_01535 543734.LCABL_28440 4.65e-186 517.0 COG1349@1|root,COG1349@2|Bacteria,1V1VH@1239|Firmicutes,4HG12@91061|Bacilli,3FC5U@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain rdrB - - ko:K02444,ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AFLMLIMI_01536 543734.LCABL_28430 8.64e-107 308.0 COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,4HPPC@91061|Bacilli,3F7U5@33958|Lactobacillaceae 91061|Bacilli G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 pts36A - 2.7.1.200 ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_EIIA_2 AFLMLIMI_01537 543734.LCABL_28420 5.31e-69 208.0 COG3414@1|root,COG3414@2|Bacteria,1VAU7@1239|Firmicutes,4IR9X@91061|Bacilli,3F7JF@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit - - 2.7.1.200 ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.5.1 - - PTS_IIB AFLMLIMI_01538 543734.LCABL_28410 0.0 944.0 COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,4HAIT@91061|Bacilli,3FCCE@33958|Lactobacillaceae 91061|Bacilli G PTS system sugar-specific permease component pts36C - - ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00279 R05570 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.5.1 - - EIIC-GAT AFLMLIMI_01540 543734.LCABL_28390 1.24e-174 486.0 COG0235@1|root,COG0235@2|Bacteria,1V57Z@1239|Firmicutes,4HGYY@91061|Bacilli,3FCAV@33958|Lactobacillaceae 91061|Bacilli G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II AFLMLIMI_01541 543734.LCABL_28380 1.1e-172 481.0 COG2188@1|root,COG2188@2|Bacteria,1TTCD@1239|Firmicutes,4HEXQ@91061|Bacilli,3F4DA@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein - - - ko:K03492 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_01542 543734.LCABL_28370 1.54e-307 839.0 COG1455@1|root,COG1455@2|Bacteria,1TSXJ@1239|Firmicutes,4HU65@91061|Bacilli,3F5IS@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane - - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_01543 543734.LCABL_28360 0.0 1742.0 COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HBC7@91061|Bacilli,3F4XS@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolases family 38 N-terminal domain mngB - 3.2.1.170 ko:K15524 - - - - ko00000,ko01000 - GH38 - Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C AFLMLIMI_01544 543734.LCABL_28350 1.98e-314 856.0 COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,4HBQW@91061|Bacilli,3F535@33958|Lactobacillaceae 91061|Bacilli S Metal-independent alpha-mannosidase (GH125) - - - ko:K09704 - - - - ko00000 - - - Glyco_hydro_125 AFLMLIMI_01545 543734.LCABL_28340 7.4e-196 544.0 COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,4HD5J@91061|Bacilli,3FBD4@33958|Lactobacillaceae 91061|Bacilli GK ROK family ypbG - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK AFLMLIMI_01546 543734.LCABL_28330 0.0 986.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bgl - 3.2.1.21,3.2.1.85,3.2.1.86 ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AFLMLIMI_01547 543734.LCABL_28320 5.16e-66 201.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F77Q@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB AFLMLIMI_01548 543734.LCABL_28310 3.09e-63 194.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3F7SW@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA AFLMLIMI_01549 543734.LCABL_28300 2.84e-192 534.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HCQB@91061|Bacilli,3FBHN@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA AFLMLIMI_01550 543734.LCABL_28290 9.8e-169 474.0 COG3715@1|root,COG3715@2|Bacteria,1UYP8@1239|Firmicutes,4HFQS@91061|Bacilli,3FC9E@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_01551 543734.LCABL_28280 2.01e-215 595.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4HIM5@91061|Bacilli,3FBI1@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man,PTSIIB_sorb AFLMLIMI_01552 543734.LCABL_28270 0.0 868.0 COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,4HDR0@91061|Bacilli,3F4YW@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos AFLMLIMI_01553 543734.LCABL_28260 2.22e-174 486.0 COG2188@1|root,COG2188@2|Bacteria,1VCJ9@1239|Firmicutes,4HM7V@91061|Bacilli,3F6DC@33958|Lactobacillaceae 91061|Bacilli K UTRA domain - - - - - - - - - - - - GntR,UTRA AFLMLIMI_01554 543734.LCABL_28240 0.0 1008.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,3F3WI@33958|Lactobacillaceae 91061|Bacilli F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N AFLMLIMI_01555 543734.LCABL_28230 2.36e-167 469.0 COG1737@1|root,COG1737@2|Bacteria,1TP26@1239|Firmicutes,4HDKG@91061|Bacilli,3F681@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain, rpiR family rpl - - - - - - - - - - - HTH_6,SIS AFLMLIMI_01556 543734.LCABL_28220 2.11e-220 608.0 COG1105@1|root,COG1105@2|Bacteria,1TTI9@1239|Firmicutes,4HCRN@91061|Bacilli,3F537@33958|Lactobacillaceae 91061|Bacilli H pfkB family carbohydrate kinase fruK-1 - 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB AFLMLIMI_01557 543734.LCABL_28210 0.0 1256.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F5D3@33958|Lactobacillaceae 91061|Bacilli GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 fruC - 2.7.1.202 ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB AFLMLIMI_01558 543734.LCABL_28200 5.24e-116 331.0 29P3K@1|root,30AWC@2|Bacteria,1U76S@1239|Firmicutes,4IH1K@91061|Bacilli,3F91T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01559 543734.LCABL_28190 4.42e-154 434.0 COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,4HB4E@91061|Bacilli,3FB62@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF554) ydfK - - ko:K07150 - - - - ko00000 - - - DUF554 AFLMLIMI_01560 543734.LCABL_28180 1.97e-235 653.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli,3F3KU@33958|Lactobacillaceae 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA - - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA AFLMLIMI_01561 543734.LCABL_28150 2.87e-289 790.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H9M3@91061|Bacilli,3F4AH@33958|Lactobacillaceae 91061|Bacilli EK Aminotransferase, class I - - - - - - - - - - - - Aminotran_1_2 AFLMLIMI_01562 543734.LCABL_28140 4.39e-213 588.0 COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,4HCXX@91061|Bacilli,3F4HW@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_01563 543734.LCABL_28130 1.38e-117 335.0 COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,4HHJ9@91061|Bacilli,3F3RG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - Cauli_VI,RNase_H AFLMLIMI_01564 543734.LCABL_28120 7.22e-197 545.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli,3F47B@33958|Lactobacillaceae 91061|Bacilli S hydrolase yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 AFLMLIMI_01565 543734.LCABL_28110 1.56e-161 452.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HJ9X@91061|Bacilli,3FC5R@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpmB - - ko:K15640 - - - - ko00000 - - - His_Phos_1 AFLMLIMI_01566 543734.LCABL_28100 8.08e-137 389.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,4HM4F@91061|Bacilli,3F5F5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 AFLMLIMI_01567 1074451.CRL705_1431 1.99e-16 73.9 2DKPT@1|root,30A91@2|Bacteria,1U6CF@1239|Firmicutes,4IG44@91061|Bacilli,3F7KP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF2187 AFLMLIMI_01568 543734.LCABL_28080 4.04e-79 234.0 29PSZ@1|root,30AR5@2|Bacteria,1U708@1239|Firmicutes,4IGUJ@91061|Bacilli,3F8T2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01569 543734.LCABL_28070 2.79e-185 516.0 COG0561@1|root,COG0561@2|Bacteria,1V8IN@1239|Firmicutes,4HJUX@91061|Bacilli,3F5CU@33958|Lactobacillaceae 91061|Bacilli S hydrolase - - - - - - - - - - - - Hydrolase_3 AFLMLIMI_01570 543734.LCABL_28060 6.25e-246 674.0 COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HAZ2@91061|Bacilli,3F414@33958|Lactobacillaceae 91061|Bacilli C Aldo keto reductase family protein yghZ - - ko:K19265 - - - - ko00000,ko01000 - - - Aldo_ket_red AFLMLIMI_01571 543734.LCABL_28050 0.0 1654.0 COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,4HTKA@91061|Bacilli,3FC8R@33958|Lactobacillaceae 91061|Bacilli L excinuclease ABC uvrA3 - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran AFLMLIMI_01572 543734.LCABL_28040 6.41e-92 269.0 29Q5J@1|root,30B4H@2|Bacteria,1U7IQ@1239|Firmicutes,4IHFG@91061|Bacilli,3F9S0@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - - - - - - - - - - MarR_2 AFLMLIMI_01573 543734.LCABL_28030 3.47e-147 415.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yagB - - ko:K06950 - - - - ko00000 - - - HD AFLMLIMI_01575 543734.LCABL_28010 1.56e-145 410.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HRQQ@91061|Bacilli,3F4Q0@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi AFLMLIMI_01576 543734.LCABL_28000 1.32e-221 612.0 COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,4HGBI@91061|Bacilli,3FBRC@33958|Lactobacillaceae 91061|Bacilli P Voltage-dependent anion channel ydiA - - ko:K11041 ko05150,map05150 - - - ko00000,ko00001,ko02042 2.A.16 - - SLAC1 AFLMLIMI_01577 543734.LCABL_27990 9.79e-194 538.0 COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,4HC4T@91061|Bacilli,3F4VC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator rlrG - - ko:K21900 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate AFLMLIMI_01578 543734.LCABL_27980 0.0 1483.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase - - - - - - - - - - - - AAA_19,UvrD_C_2 AFLMLIMI_01580 543734.LCABL_27970 0.0 956.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,3F44S@33958|Lactobacillaceae 91061|Bacilli EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) choS - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC AFLMLIMI_01581 543734.LCABL_27960 3.51e-224 618.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli,3F55H@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran AFLMLIMI_01582 543734.LCABL_27950 0.0 870.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim AFLMLIMI_01583 543734.LCABL_27900 4.24e-246 675.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli,3F3V6@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b AFLMLIMI_01584 543734.LCABL_27890 8.42e-135 382.0 COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,4HH6X@91061|Bacilli,3FCF0@33958|Lactobacillaceae 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA AFLMLIMI_01585 543734.LCABL_27880 1.19e-155 442.0 COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4HJVB@91061|Bacilli,3F5HD@33958|Lactobacillaceae 91061|Bacilli S TPM domain - - - ko:K06872 - - - - ko00000 - - - TPM_phosphatase AFLMLIMI_01586 543734.LCABL_27870 5.58e-306 836.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli,3FC3X@33958|Lactobacillaceae 91061|Bacilli V MatE dinF - - - - - - - - - - - MatE AFLMLIMI_01587 543734.LCABL_27860 6.5e-119 339.0 COG1247@1|root,COG1247@2|Bacteria,1V3V3@1239|Firmicutes,4HHNY@91061|Bacilli,3F70T@33958|Lactobacillaceae 91061|Bacilli M Acetyltransferase (GNAT) domain ywnH GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_1,Acetyltransf_3,Acetyltransf_4 AFLMLIMI_01588 543734.LCABL_27850 5.94e-198 548.0 COG0500@1|root,COG2226@2|Bacteria,1UIXT@1239|Firmicutes,4ISW5@91061|Bacilli 91061|Bacilli Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_23,Methyltransf_25 AFLMLIMI_01589 543734.LCABL_27840 2.48e-224 618.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red AFLMLIMI_01590 543734.LCABL_27830 0.0 984.0 COG0248@1|root,COG0248@2|Bacteria,1VT8Q@1239|Firmicutes,4HB84@91061|Bacilli,3F49N@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx3 - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - HD,Ppx-GppA AFLMLIMI_01591 543734.LCABL_27820 0.0 1415.0 COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,4HA88@91061|Bacilli,3F3PE@33958|Lactobacillaceae 91061|Bacilli P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N AFLMLIMI_01592 543734.LCABL_27810 2.57e-223 615.0 COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,4HAQS@91061|Bacilli,3F3SR@33958|Lactobacillaceae 91061|Bacilli FP exopolyphosphatase ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA AFLMLIMI_01593 1423732.BALS01000010_gene1903 5.77e-204 568.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli,3FBNF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1002) ypuA - - - - - - - - - - - DUF1002 AFLMLIMI_01594 543734.LCABL_27790 4.7e-50 159.0 29BUI@1|root,2ZYSU@2|Bacteria,1U6QJ@1239|Firmicutes,4IGHU@91061|Bacilli,3F8B7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01595 543734.LCABL_27780 1.31e-124 354.0 COG1881@1|root,COG1881@2|Bacteria,1VJEE@1239|Firmicutes,4HXTJ@91061|Bacilli,3F75J@33958|Lactobacillaceae 91061|Bacilli S Phosphatidylethanolamine-binding protein yxkA - - ko:K06910 - - - - ko00000 - - - PBP AFLMLIMI_01597 543734.LCABL_27770 5.59e-220 607.0 296WI@1|root,2ZU5A@2|Bacteria,1VT7R@1239|Firmicutes,4HVBN@91061|Bacilli,3F4R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01598 543734.LCABL_27760 6.41e-24 90.5 29QQH@1|root,30BQA@2|Bacteria,1U8GG@1239|Firmicutes,4IIE9@91061|Bacilli,3FAYF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01599 543734.LCABL_27750 5.67e-165 461.0 COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,4HGHS@91061|Bacilli,3FC3Y@33958|Lactobacillaceae 91061|Bacilli K Sir2 family cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 AFLMLIMI_01600 543734.LCABL_27740 9.14e-139 392.0 COG3548@1|root,COG3548@2|Bacteria,1VAQZ@1239|Firmicutes,4HJFH@91061|Bacilli,3F6Q5@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) yiiE - - - - - - - - - - - DUF1211 AFLMLIMI_01601 543734.LCABL_27730 3.11e-218 602.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli,3F4M2@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N AFLMLIMI_01602 543734.LCABL_27720 1.09e-118 338.0 COG1051@1|root,COG1051@2|Bacteria,1VAC7@1239|Firmicutes,4HKN6@91061|Bacilli,3F7HC@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX AFLMLIMI_01603 543734.LCABL_27710 2.07e-196 544.0 COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,4HA0X@91061|Bacilli,3F40Y@33958|Lactobacillaceae 91061|Bacilli F Protein of unknown function DUF72 yunF - - - - - - - - - - - DUF72 AFLMLIMI_01604 543734.LCABL_27700 4.11e-223 613.0 COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,3F40N@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepI - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 AFLMLIMI_01605 543734.LCABL_27690 0.0 1325.0 COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,3F3XR@33958|Lactobacillaceae 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind AFLMLIMI_01606 543734.LCABL_27680 0.0 1163.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F53S@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran AFLMLIMI_01607 543734.LCABL_27670 0.0 1158.0 COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,4HDMH@91061|Bacilli,3F604@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_tran AFLMLIMI_01608 543734.LCABL_27660 5.83e-199 553.0 COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,4HQIT@91061|Bacilli 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c_5,SPOB_a AFLMLIMI_01609 543734.LCABL_27650 4.11e-160 449.0 COG3279@1|root,COG3279@2|Bacteria,1TRDQ@1239|Firmicutes,4HP0H@91061|Bacilli,3FC2V@33958|Lactobacillaceae 91061|Bacilli T LytTr DNA-binding domain - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg AFLMLIMI_01610 543734.LCABL_27640 7.08e-220 605.0 COG2017@1|root,COG2017@2|Bacteria,1V3WP@1239|Firmicutes,4HHIH@91061|Bacilli,3F5RU@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase yqhA - - - - - - - - - - - Aldose_epim AFLMLIMI_01611 543734.LCABL_27630 1.35e-239 658.0 COG3684@1|root,COG3684@2|Bacteria,1TQRR@1239|Firmicutes,4HBS9@91061|Bacilli,3F3UA@33958|Lactobacillaceae 91061|Bacilli G Belongs to the aldolase LacD family lacD - 4.1.2.40 ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC AFLMLIMI_01612 543734.LCABL_27620 2.57e-104 302.0 COG1762@1|root,COG1762@2|Bacteria 2|Bacteria G phosphoenolpyruvate-dependent sugar phosphotransferase system manR - 2.7.1.194,2.7.1.200,2.7.1.202,2.7.1.204 ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 M00273,M00279,M00283,M00306,M00550,M00807 R03232,R05570,R07671,R11171 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 4.A.2.1,4.A.5,4.A.5.1,4.A.7.1 - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB AFLMLIMI_01613 543734.LCABL_27610 2.5e-187 520.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,3F3N2@33958|Lactobacillaceae 91061|Bacilli L hydrolase, TatD family tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase AFLMLIMI_01614 543734.LCABL_27600 6.78e-130 369.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,3F64F@33958|Lactobacillaceae 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 AFLMLIMI_01615 543734.LCABL_27590 2.04e-202 561.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,3F3VC@33958|Lactobacillaceae 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD AFLMLIMI_01616 543734.LCABL_27580 4.13e-51 161.0 COG4466@1|root,COG4466@2|Bacteria,1VEQM@1239|Firmicutes,4HKF8@91061|Bacilli,3F7D3@33958|Lactobacillaceae 91061|Bacilli S Biofilm formation stimulator VEG veg - - - - - - - - - - - VEG AFLMLIMI_01617 543734.LCABL_27570 6.63e-232 637.0 COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,3F43W@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096,M00582 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.29 - iYO844.BSU00460 GHMP_kinases_C,GHMP_kinases_N AFLMLIMI_01618 543734.LCABL_27560 1.99e-205 568.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3F4KJ@33958|Lactobacillaceae 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux AFLMLIMI_01619 543734.LCABL_27550 5.89e-158 445.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli,3F4P1@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised protein family (UPF0014) ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 AFLMLIMI_01620 543734.LCABL_27540 1.29e-154 434.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli,3F4UY@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran AFLMLIMI_01621 543734.LCABL_27530 1.01e-193 538.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli,3F3NH@33958|Lactobacillaceae 91061|Bacilli F pur operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N AFLMLIMI_01622 543734.LCABL_27520 5.97e-285 778.0 COG4767@1|root,COG4767@2|Bacteria,1V04Y@1239|Firmicutes,4HDS5@91061|Bacilli,3F3SH@33958|Lactobacillaceae 91061|Bacilli V RDD family ysaA - - - - - - - - - - - RDD,VanZ AFLMLIMI_01623 543734.LCABL_27510 3.29e-299 820.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3F4I3@33958|Lactobacillaceae 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase AFLMLIMI_01624 1423816.BACQ01000037_gene1564 2.2e-225 622.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N AFLMLIMI_01625 543734.LCABL_27480 2.56e-72 217.0 COG4043@1|root,COG4043@2|Bacteria,1VEJD@1239|Firmicutes,4HNU5@91061|Bacilli 91061|Bacilli S ASCH nudA - - - - - - - - - - - ASCH AFLMLIMI_01626 1423816.BACQ01000037_gene1565 1.88e-244 676.0 COG0786@1|root,COG0786@2|Bacteria,1TS2B@1239|Firmicutes,4HCID@91061|Bacilli,3F5R6@33958|Lactobacillaceae 91061|Bacilli E glutamate:sodium symporter activity - - - - - - - - - - - - - AFLMLIMI_01627 1423816.BACQ01000037_gene1566 1.56e-295 810.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,3F541@33958|Lactobacillaceae 91061|Bacilli E Peptidase dimerisation domain dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AFLMLIMI_01628 1423816.BACQ01000037_gene1567 1.06e-262 722.0 COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli,3F4D3@33958|Lactobacillaceae 91061|Bacilli Q Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 AFLMLIMI_01629 543734.LCABL_27460 1.31e-77 231.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,3F6YZ@33958|Lactobacillaceae 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL AFLMLIMI_01630 543734.LCABL_27450 2.14e-237 654.0 COG1434@1|root,COG1434@2|Bacteria,1UR34@1239|Firmicutes,4HDF2@91061|Bacilli,3F4J5@33958|Lactobacillaceae 91061|Bacilli S DUF218 domain - - - - - - - - - - - - DUF218 AFLMLIMI_01631 1423816.BACQ01000037_gene1572 1.41e-103 299.0 COG0494@1|root,COG0494@2|Bacteria,1VD6I@1239|Firmicutes,4HKRW@91061|Bacilli,3F75N@33958|Lactobacillaceae 91061|Bacilli L NUDIX domain mutT - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX AFLMLIMI_01632 543734.LCABL_27430 0.0 923.0 COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,4HAX8@91061|Bacilli,3F442@33958|Lactobacillaceae 91061|Bacilli S HD domain protein ywfO GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD AFLMLIMI_01633 543734.LCABL_27420 1.99e-200 555.0 COG0095@1|root,COG0095@2|Bacteria,1TQKA@1239|Firmicutes,4HCPS@91061|Bacilli,3F575@33958|Lactobacillaceae 91061|Bacilli H biotin lipoate A B protein ligase lipL GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.200,2.3.1.204 ko:K16869,ko:K18821 - - - - ko00000,ko01000 - - - BPL_LplA_LipB AFLMLIMI_01634 543734.LCABL_27410 3.48e-103 298.0 COG4506@1|root,COG4506@2|Bacteria,1V8IZ@1239|Firmicutes,4HIW0@91061|Bacilli,3F6AI@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 AFLMLIMI_01635 543734.LCABL_27400 1.15e-111 326.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli,3F55D@33958|Lactobacillaceae 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH AFLMLIMI_01636 543734.LCABL_27390 3.42e-202 560.0 COG3548@1|root,COG3548@2|Bacteria,1VNI3@1239|Firmicutes,4HSHZ@91061|Bacilli,3F5J9@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1211) ybbB - - - - - - - - - - - DUF1211 AFLMLIMI_01637 543734.LCABL_27380 0.0 1066.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,3F42X@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase AFLMLIMI_01638 543734.LCABL_27370 9.48e-300 818.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli,3F3P8@33958|Lactobacillaceae 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase AFLMLIMI_01639 543734.LCABL_27360 2.28e-57 177.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HKF0@91061|Bacilli,3F7D7@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L31 rpmE2 - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 AFLMLIMI_01640 1423816.BACQ01000043_gene1667 2.29e-87 258.0 29Q2X@1|root,30B1I@2|Bacteria,1U7DP@1239|Firmicutes,4IH9K@91061|Bacilli,3F9FK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01641 543734.LCABL_27340 2.61e-163 456.0 2DNW7@1|root,32ZGM@2|Bacteria,1V8QF@1239|Firmicutes,4HIIB@91061|Bacilli,3F601@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01642 543734.LCABL_27330 3.57e-158 442.0 COG0457@1|root,COG0457@2|Bacteria,1VQ45@1239|Firmicutes,4HRFF@91061|Bacilli,3F62R@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - SUKH_6 AFLMLIMI_01643 568703.LGG_00849 4.87e-08 52.8 29QSF@1|root,30BSA@2|Bacteria,1U8JX@1239|Firmicutes,4IIHW@91061|Bacilli,3FB2A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01644 543734.LCABL_27320 4.87e-187 519.0 29SV9@1|root,30E1E@2|Bacteria,1V46E@1239|Firmicutes,4HI7R@91061|Bacilli,3F6E2@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01645 543734.LCABL_27310 0.0 904.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli,3F4SK@33958|Lactobacillaceae 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M AFLMLIMI_01646 543734.LCABL_27300 0.0 962.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,3F46Q@33958|Lactobacillaceae 91061|Bacilli F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C AFLMLIMI_01647 543734.LCABL_27290 2.63e-82 243.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli,3F6HC@33958|Lactobacillaceae 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS AFLMLIMI_01648 543734.LCABL_27280 1.14e-277 758.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli,3F3X2@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N AFLMLIMI_01649 1423816.BACQ01000044_gene1675 4.66e-44 144.0 29PVB@1|root,30ATJ@2|Bacteria,1U736@1239|Firmicutes,4IGXQ@91061|Bacilli,3F8WZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01650 543734.LCABL_27260 5.68e-83 245.0 COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,4HGXF@91061|Bacilli,3F6Y9@33958|Lactobacillaceae 91061|Bacilli L Toxic component of a toxin-antitoxin (TA) module ndoA - - ko:K07171 - - - - ko00000,ko01000,ko02048 - - - PemK_toxin AFLMLIMI_01651 543734.LCABL_27250 1.63e-111 321.0 COG4708@1|root,COG4708@2|Bacteria,1V463@1239|Firmicutes,4HH0P@91061|Bacilli,3FCEF@33958|Lactobacillaceae 91061|Bacilli S QueT transporter queT - - - - - - - - - - - QueT AFLMLIMI_01652 543734.LCABL_27240 0.0 2945.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,4HA4G@91061|Bacilli,3F4TU@33958|Lactobacillaceae 91061|Bacilli E GXGXG motif gltA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase AFLMLIMI_01653 543734.LCABL_27230 0.0 979.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4HAD5@91061|Bacilli,3FB6A@33958|Lactobacillaceae 91061|Bacilli E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - iSB619.SA_RS02450 Fer4_20,Pyr_redox_2 AFLMLIMI_01654 543734.LCABL_27220 4.85e-168 469.0 COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,3F6PH@33958|Lactobacillaceae 91061|Bacilli M ErfK YbiS YcfS YnhG yciB - - - - - - - - - - - YkuD AFLMLIMI_01655 543734.LCABL_27210 1.34e-154 434.0 COG0517@1|root,COG0517@2|Bacteria,1TR5G@1239|Firmicutes,4H9ZA@91061|Bacilli,3F3JY@33958|Lactobacillaceae 91061|Bacilli S (CBS) domain - - - - - - - - - - - - CBS AFLMLIMI_01656 543734.LCABL_27170 0.0 911.0 COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,4HDTN@91061|Bacilli,3F3QW@33958|Lactobacillaceae 91061|Bacilli S Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_4,YkuD AFLMLIMI_01657 543734.LCABL_27160 5.04e-232 639.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli,3F3RM@33958|Lactobacillaceae 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N AFLMLIMI_01658 543734.LCABL_27150 4.28e-131 372.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3F3VZ@33958|Lactobacillaceae 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro AFLMLIMI_01659 543734.LCABL_27140 0.0 2267.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,3F4KU@33958|Lactobacillaceae 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF AFLMLIMI_01660 543734.LCABL_27130 0.0 961.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4HACG@91061|Bacilli,3F4BV@33958|Lactobacillaceae 91061|Bacilli S Polysaccharide biosynthesis protein yabM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C AFLMLIMI_01661 543734.LCABL_27120 1.15e-52 166.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli,3F7JX@33958|Lactobacillaceae 91061|Bacilli J S4 domain protein yabO - - - - - - - - - - - S4 AFLMLIMI_01662 543734.LCABL_27110 7.17e-87 256.0 COG2919@1|root,COG2919@2|Bacteria 2|Bacteria D cell cycle divIC - - ko:K05589,ko:K13052 - - - - ko00000,ko03036 - - - DivIC AFLMLIMI_01663 543734.LCABL_27100 1.17e-105 305.0 COG1098@1|root,COG1098@2|Bacteria,1V6FE@1239|Firmicutes,4HIKM@91061|Bacilli,3F6HV@33958|Lactobacillaceae 91061|Bacilli J RNA binding yabR - - ko:K07571 - - - - ko00000 - - - S1 AFLMLIMI_01664 543734.LCABL_27090 1.09e-309 844.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,3F4GY@33958|Lactobacillaceae 91061|Bacilli J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C AFLMLIMI_01665 543734.LCABL_27080 1.14e-124 355.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli,3F56C@33958|Lactobacillaceae 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran AFLMLIMI_01666 543734.LCABL_27070 0.0 1261.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli,3F49Z@33958|Lactobacillaceae 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 AFLMLIMI_01667 543734.LCABL_27060 0.0 1647.0 COG4886@1|root,COG4886@2|Bacteria,1VUWY@1239|Firmicutes,4HVSW@91061|Bacilli,3F94G@33958|Lactobacillaceae 91061|Bacilli S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - AFLMLIMI_01668 543734.LCABL_27050 5.59e-249 683.0 COG4072@1|root,COG4072@2|Bacteria,1V92G@1239|Firmicutes,4HIJ2@91061|Bacilli,3F9EF@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function C-terminal (DUF3324) - - - - - - - - - - - - DUF3324,DUF916 AFLMLIMI_01669 543734.LCABL_27040 3.87e-240 661.0 COG4072@1|root,COG4072@2|Bacteria,1U765@1239|Firmicutes,4IH0X@91061|Bacilli,3F910@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF916) - - - - - - - - - - - - DUF3324,DUF916 AFLMLIMI_01670 543734.LCABL_27020 1.52e-208 577.0 29Q36@1|root,30B1U@2|Bacteria,1U7E3@1239|Firmicutes,4IH9Z@91061|Bacilli,3F9G9@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL AFLMLIMI_01671 543734.LCABL_27010 9.89e-207 572.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,3F42B@33958|Lactobacillaceae 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 AFLMLIMI_01672 543734.LCABL_27000 5.32e-242 664.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli,3F4C6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus AFLMLIMI_01673 543734.LCABL_26990 0.0 1003.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli,3F439@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon AFLMLIMI_01674 568703.LGG_00302 1.45e-46 149.0 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,3F8E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01677 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - AFLMLIMI_01687 543734.LCABL_26840 4.32e-105 303.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli,3F53E@33958|Lactobacillaceae 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR AFLMLIMI_01688 543734.LCABL_26830 0.0 1601.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR AFLMLIMI_01689 543734.LCABL_26820 0.0 2353.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli,3F4ET@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 AFLMLIMI_01690 543734.LCABL_26800 0.0 2407.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli,3F3KF@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 AFLMLIMI_01691 1423816.BACQ01000061_gene2309 8.99e-48 159.0 29Q94@1|root,30B88@2|Bacteria,1U7QC@1239|Firmicutes,4IHMP@91061|Bacilli,3FA0H@33958|Lactobacillaceae 91061|Bacilli - - - - 3.4.23.43 ko:K02236 - M00429 - - ko00000,ko00002,ko01000,ko02044 - - - - AFLMLIMI_01692 543734.LCABL_26780 0.0 5116.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F7WQ@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor AFLMLIMI_01693 543734.LCABL_26770 1.11e-92 271.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli,3F64B@33958|Lactobacillaceae 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 AFLMLIMI_01694 1423732.BALS01000083_gene2031 2.06e-108 312.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli,3F3RX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 AFLMLIMI_01695 543734.LCABL_26750 0.0 1377.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,3F3JR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 AFLMLIMI_01696 543734.LCABL_26740 4.13e-256 701.0 COG2378@1|root,COG2378@2|Bacteria,1VVQ0@1239|Firmicutes,4HW20@91061|Bacilli,3FB7T@33958|Lactobacillaceae 91061|Bacilli K WYL domain - - - - - - - - - - - - WYL AFLMLIMI_01697 543734.LCABL_26730 6.83e-138 389.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HVUV@91061|Bacilli,3FCCT@33958|Lactobacillaceae 91061|Bacilli O C-terminal domain of 1-Cys peroxiredoxin ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA AFLMLIMI_01698 543734.LCABL_26720 3.63e-90 265.0 COG3223@1|root,COG3223@2|Bacteria,1V9CG@1239|Firmicutes,4HIMW@91061|Bacilli 91061|Bacilli S Phosphate-starvation-inducible E psiE - - ko:K13256 - - - - ko00000 - - - PsiE AFLMLIMI_01699 543734.LCABL_26710 4.46e-66 201.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli,3F6KC@33958|Lactobacillaceae 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 AFLMLIMI_01700 543734.LCABL_26700 4.01e-146 412.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli,3F45I@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 AFLMLIMI_01701 543734.LCABL_26690 1.98e-140 397.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli,3F3QD@33958|Lactobacillaceae 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 AFLMLIMI_01702 543734.LCABL_26680 1.02e-61 189.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli,3F6Z2@33958|Lactobacillaceae 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 AFLMLIMI_01703 543734.LCABL_26670 7.23e-201 556.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,3F3XI@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C AFLMLIMI_01704 1423732.BALS01000005_gene1073 5.26e-63 192.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 AFLMLIMI_01705 1423732.BALS01000005_gene1074 4.5e-73 219.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,3F6K6@33958|Lactobacillaceae 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 AFLMLIMI_01706 543734.LCABL_26640 6.88e-152 427.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli,3F3Q8@33958|Lactobacillaceae 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C AFLMLIMI_01707 543734.LCABL_26630 1.38e-98 286.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,3F653@33958|Lactobacillaceae 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 AFLMLIMI_01708 543734.LCABL_26620 3.55e-33 115.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,3F82Z@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 AFLMLIMI_01709 543734.LCABL_26610 5.93e-55 171.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,3F7FX@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 AFLMLIMI_01710 543734.LCABL_26600 1.73e-77 231.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli,3F6GT@33958|Lactobacillaceae 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 AFLMLIMI_01711 543734.LCABL_26590 4.1e-67 203.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,3F6X5@33958|Lactobacillaceae 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 AFLMLIMI_01712 1423816.BACQ01000060_gene2284 8.67e-124 353.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli,3F3Q7@33958|Lactobacillaceae 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C AFLMLIMI_01713 543734.LCABL_26570 1.32e-88 260.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,3F64E@33958|Lactobacillaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 AFLMLIMI_01714 543734.LCABL_26560 2.61e-123 351.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3F4G5@33958|Lactobacillaceae 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 AFLMLIMI_01715 543734.LCABL_26550 1.62e-76 228.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli,3F6KN@33958|Lactobacillaceae 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p AFLMLIMI_01716 543734.LCABL_26540 5.74e-109 314.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,3F3VY@33958|Lactobacillaceae 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C AFLMLIMI_01717 543734.LCABL_26530 2.6e-33 115.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli,3F7ZU@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 AFLMLIMI_01718 543734.LCABL_26520 4.07e-92 270.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,3F675@33958|Lactobacillaceae 91061|Bacilli J Binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A AFLMLIMI_01719 543734.LCABL_26510 2.01e-303 829.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli,3F4FV@33958|Lactobacillaceae 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY AFLMLIMI_01720 543734.LCABL_26500 1.29e-155 436.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,3F3KB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid AFLMLIMI_01721 543734.LCABL_26490 4.15e-46 148.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a AFLMLIMI_01722 543734.LCABL_26480 6.38e-20 79.7 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,4HR2X@91061|Bacilli,3F8TC@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 AFLMLIMI_01723 543734.LCABL_26470 5.37e-76 227.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli,3F6GN@33958|Lactobacillaceae 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 AFLMLIMI_01724 543734.LCABL_26460 3.82e-82 243.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,3F67D@33958|Lactobacillaceae 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 AFLMLIMI_01725 543734.LCABL_26450 1.26e-218 603.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli,3F3W6@33958|Lactobacillaceae 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L AFLMLIMI_01726 543734.LCABL_26440 5.46e-81 240.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli,3F6GJ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 AFLMLIMI_01727 543734.LCABL_26430 2.01e-141 401.0 2BKGG@1|root,32EXB@2|Bacteria,1U7Q7@1239|Firmicutes,4IHMI@91061|Bacilli,3FA0B@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01728 543734.LCABL_26420 1.15e-197 548.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli,3F3VD@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran AFLMLIMI_01729 543734.LCABL_26410 1.92e-202 560.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli,3F48E@33958|Lactobacillaceae 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran AFLMLIMI_01730 543734.LCABL_26400 1.13e-181 506.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,3F3UW@33958|Lactobacillaceae 91061|Bacilli U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ AFLMLIMI_01731 543734.LCABL_26390 1.39e-178 497.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3F4KC@33958|Lactobacillaceae 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 AFLMLIMI_01732 543734.LCABL_26380 6.26e-169 473.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HUDT@91061|Bacilli,3FC68@33958|Lactobacillaceae 91061|Bacilli K TipAS antibiotic-recognition domain tipA - - - - - - - - - - - MerR_1,TipAS AFLMLIMI_01733 1423732.BALS01000005_gene1101 1.5e-44 144.0 29PH8@1|root,30AFD@2|Bacteria,1U6KC@1239|Firmicutes,4IGD6@91061|Bacilli,3F83D@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01734 543734.LCABL_26360 7.4e-164 459.0 COG1136@1|root,COG1136@2|Bacteria,1UYJ6@1239|Firmicutes,4HF89@91061|Bacilli,3F5SR@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities lolD - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_01735 543734.LCABL_26350 2.91e-235 649.0 COG0577@1|root,COG0577@2|Bacteria,1TVQ4@1239|Firmicutes,4IRU4@91061|Bacilli,3FBQ0@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX AFLMLIMI_01736 543734.LCABL_26340 5.95e-140 395.0 COG1309@1|root,COG1309@2|Bacteria,1VD4H@1239|Firmicutes,4HNBF@91061|Bacilli,3F5VC@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AFLMLIMI_01737 543734.LCABL_26330 2.98e-104 301.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,3F696@33958|Lactobacillaceae 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 AFLMLIMI_01738 543734.LCABL_26320 8.98e-86 253.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,3F656@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 AFLMLIMI_01739 543734.LCABL_26310 1.02e-71 215.0 2E9Y3@1|root,32JRV@2|Bacteria,1TVPM@1239|Firmicutes,4I3SR@91061|Bacilli,3FA3I@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01740 543734.LCABL_26300 1.26e-105 318.0 2BQ3C@1|root,32IXT@2|Bacteria,1U82X@1239|Firmicutes,4II0B@91061|Bacilli,3FAGQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01741 543734.LCABL_26280 1.23e-08 58.9 299D6@1|root,2ZWG2@2|Bacteria,1V564@1239|Firmicutes,4HI66@91061|Bacilli,3F6SE@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2785) - - - - - - - - - - - - DUF2785 AFLMLIMI_01742 543734.LCABL_26260 2.47e-169 477.0 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,3F5QG@33958|Lactobacillaceae 91061|Bacilli S ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_01743 543734.LCABL_26250 4.08e-171 479.0 COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HFPQ@91061|Bacilli,3F66B@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein XK27_06945 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 AFLMLIMI_01744 543734.LCABL_26240 5.36e-173 484.0 COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,3F5Q6@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein XK27_06950 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 AFLMLIMI_01745 543734.LCABL_26230 2.8e-190 528.0 COG0600@1|root,COG0600@2|Bacteria,1TQ26@1239|Firmicutes,4HCJ7@91061|Bacilli,3F4W8@33958|Lactobacillaceae 91061|Bacilli U Binding-protein-dependent transport system inner membrane component ssuC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0042908,GO:0042910,GO:0042918,GO:0042959,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K15554 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.17.2 - - BPD_transp_1 AFLMLIMI_01746 543734.LCABL_26220 1.17e-154 435.0 COG1116@1|root,COG1116@2|Bacteria,1TRE2@1239|Firmicutes,4HAHM@91061|Bacilli,3F5YE@33958|Lactobacillaceae 91061|Bacilli P ATPases associated with a variety of cellular activities ssuB - - ko:K15555 ko00920,ko02010,map00920,map02010 M00436 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.17.2 - - ABC_tran AFLMLIMI_01747 543734.LCABL_26210 2.6e-297 811.0 COG1835@1|root,COG1835@2|Bacteria,1V8A9@1239|Firmicutes,4HJ67@91061|Bacilli,3F5JA@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 AFLMLIMI_01748 543734.LCABL_26200 0.0 1010.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,3FC48@33958|Lactobacillaceae 91061|Bacilli IQ AMP-binding enzyme C-terminal domain - - 6.2.1.48 ko:K02182 - - - - ko00000,ko01000 - - - AMP-binding,AMP-binding_C AFLMLIMI_01749 543734.LCABL_26190 1.09e-225 622.0 COG0715@1|root,COG0715@2|Bacteria,1TPI2@1239|Firmicutes,4HDP6@91061|Bacilli,3F4DK@33958|Lactobacillaceae 91061|Bacilli P NMT1-like family ssuA - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 AFLMLIMI_01750 543734.LCABL_26170 3.27e-187 520.0 COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,4HBI5@91061|Bacilli,3FBJQ@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component ptxC - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 AFLMLIMI_01751 543734.LCABL_26160 1e-173 486.0 COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,4HBT8@91061|Bacilli,3F58M@33958|Lactobacillaceae 91061|Bacilli P Binding-protein-dependent transport system inner membrane component phnB - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 AFLMLIMI_01752 543734.LCABL_26150 1.01e-176 493.0 COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,4HC3N@91061|Bacilli,3F3SJ@33958|Lactobacillaceae 91061|Bacilli P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC GO:0006810,GO:0008150,GO:0015716,GO:0051179,GO:0051234,GO:0071702 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran AFLMLIMI_01753 543734.LCABL_26140 1.99e-212 588.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,3F3KK@33958|Lactobacillaceae 91061|Bacilli P Phosphonate ABC transporter phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd AFLMLIMI_01754 543734.LCABL_26130 2.3e-22 88.6 COG0148@1|root,COG0148@2|Bacteria 2|Bacteria G phosphopyruvate hydratase activity eno GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0043236,GO:0050840 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N AFLMLIMI_01757 1423816.BACQ01000075_gene2596 2.02e-46 150.0 COG2944@1|root,COG2944@2|Bacteria,1VEWZ@1239|Firmicutes,4HP6G@91061|Bacilli,3F82N@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07726 - - - - ko00000,ko03000 - - - HTH_3,MqsA_antitoxin AFLMLIMI_01758 543734.LCABL_26110 7.25e-88 258.0 COG0239@1|root,COG0239@2|Bacteria,1U4G6@1239|Firmicutes,4IE88@91061|Bacilli,3F6R4@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB1 - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB AFLMLIMI_01759 543734.LCABL_26100 3.56e-68 207.0 COG0239@1|root,COG0239@2|Bacteria,1VM30@1239|Firmicutes,4HRC4@91061|Bacilli,3F8A8@33958|Lactobacillaceae 91061|Bacilli U Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB AFLMLIMI_01764 1423816.BACQ01000060_gene2301 4.37e-153 476.0 2ED61@1|root,3372S@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - AFLMLIMI_01767 543734.LCABL_26060 2.1e-27 99.4 29QM9@1|root,30BKW@2|Bacteria,1U8AT@1239|Firmicutes,4II8S@91061|Bacilli,3FAS5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01768 543734.LCABL_26040 1.71e-210 582.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA AFLMLIMI_01769 543734.LCABL_26030 0.0 922.0 COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,3F4FM@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,Gram_pos_anchor AFLMLIMI_01770 543734.LCABL_26020 2.87e-101 295.0 29Q79@1|root,30B6A@2|Bacteria,1U7MC@1239|Firmicutes,4IHIH@91061|Bacilli,3F9WH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01771 543734.LCABL_26010 3.3e-145 409.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain yjhB - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,Nudix_N AFLMLIMI_01772 543734.LCABL_26000 2.83e-152 427.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 AFLMLIMI_01773 543734.LCABL_25990 6.75e-215 593.0 COG0803@1|root,COG0803@2|Bacteria,1V110@1239|Firmicutes,4HZ7G@91061|Bacilli,3FBJR@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K02077,ko:K11707 ko02010,map02010 M00244,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA AFLMLIMI_01774 543734.LCABL_25960 8.32e-56 174.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HKK1@91061|Bacilli,3F7KX@33958|Lactobacillaceae 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 AFLMLIMI_01775 543734.LCABL_25950 0.0 954.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family aldA - 1.2.1.21,1.2.1.22 ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 - R00203,R01333,R01446 RC00080,RC00104,RC00242 ko00000,ko00001,ko01000 - - - Aldedh AFLMLIMI_01776 543734.LCABL_25940 3.38e-170 476.0 COG1121@1|root,COG1121@2|Bacteria,1UM08@1239|Firmicutes 1239|Firmicutes P AAA domain, putative AbiEii toxin, Type IV TA system - - 3.6.3.35 ko:K19973 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15.15 - - ABC_tran AFLMLIMI_01777 543734.LCABL_25930 5.89e-185 517.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli,3F4JM@33958|Lactobacillaceae 91061|Bacilli U ABC 3 transport family mtsB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K19972,ko:K19976 ko02010,map02010 M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2 - - ABC-3 AFLMLIMI_01778 543734.LCABL_25920 3.81e-225 620.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli,3F4B9@33958|Lactobacillaceae 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family mntA - - ko:K19975,ko:K19976 ko02010,map02010 M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.15 - - ZnuA AFLMLIMI_01779 543734.LCABL_25900 1.23e-69 210.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,3F7DH@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, ArsR family czrA - - ko:K22043 - - - - ko00000,ko03000 - - - HTH_5 AFLMLIMI_01780 543734.LCABL_25890 1.83e-143 405.0 COG0053@1|root,COG0053@2|Bacteria,1V9B6@1239|Firmicutes,4HJTJ@91061|Bacilli,3F4M1@33958|Lactobacillaceae 91061|Bacilli P Cation efflux family - - - - - - - - - - - - Cation_efflux AFLMLIMI_01781 543734.LCABL_25880 8.86e-35 119.0 2FB4N@1|root,343B1@2|Bacteria,1VZEN@1239|Firmicutes,4HYPA@91061|Bacilli,3F944@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01782 543734.LCABL_25870 0.0 1072.0 COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4HDD6@91061|Bacilli,3F3XB@33958|Lactobacillaceae 91061|Bacilli Q Multicopper oxidase sufI - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 AFLMLIMI_01783 543734.LCABL_25860 1.27e-305 836.0 COG0477@1|root,COG0477@2|Bacteria,1UJ8F@1239|Firmicutes,4IT4C@91061|Bacilli,3FBUG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_5 AFLMLIMI_01784 1423732.BALS01000064_gene2233 1.14e-72 219.0 29PE3@1|root,32D7A@2|Bacteria,1U7IM@1239|Firmicutes,4IHFA@91061|Bacilli,3F9RV@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01785 543734.LCABL_25840 0.0 1705.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase atp2C1 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 AFLMLIMI_01786 543734.LCABL_25830 0.0 946.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp AFLMLIMI_01787 543734.LCABL_25820 6.42e-28 100.0 2BSE3@1|root,32MG2@2|Bacteria,1U8AV@1239|Firmicutes,4II8V@91061|Bacilli,3FASA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01788 543734.LCABL_25810 3.65e-172 481.0 29Q1N@1|root,30B08@2|Bacteria,1U7C1@1239|Firmicutes,4IH7B@91061|Bacilli,3F9BP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01789 543734.LCABL_25800 0.0 879.0 COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,3F3K0@33958|Lactobacillaceae 91061|Bacilli C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09430 FumaraseC_C,Lyase_1 AFLMLIMI_01790 543734.LCABL_25790 3.66e-274 750.0 COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,4HAS5@91061|Bacilli,3F3UQ@33958|Lactobacillaceae 91061|Bacilli C Oxidoreductase yqiG - - - - - - - - - - - Oxidored_FMN AFLMLIMI_01791 543734.LCABL_25780 3.51e-166 465.0 COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,3F468@33958|Lactobacillaceae 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short AFLMLIMI_01792 543734.LCABL_25770 4.84e-230 633.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli,3F4U1@33958|Lactobacillaceae 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red AFLMLIMI_01796 543734.LCABL_25730 1.67e-63 197.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F59K@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac AFLMLIMI_01797 543734.LCABL_25730 1.31e-58 185.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli,3F59K@33958|Lactobacillaceae 91061|Bacilli S Maltose acetyltransferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep,Hexapep_2,Mac AFLMLIMI_01798 543734.LCABL_25720 3.38e-72 217.0 2CCCW@1|root,2ZFAQ@2|Bacteria,1W39Y@1239|Firmicutes,4I054@91061|Bacilli,3F8D6@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun AFLMLIMI_01800 543734.LCABL_25690 5.62e-75 224.0 29PYM@1|root,30AX3@2|Bacteria,1U77W@1239|Firmicutes,4IH2P@91061|Bacilli,3F935@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01802 543734.LCABL_25670 6.99e-182 508.0 COG1266@1|root,COG1266@2|Bacteria,1W74D@1239|Firmicutes,4HXYG@91061|Bacilli,3F80E@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi AFLMLIMI_01806 568703.LGG_02391 1.81e-15 69.7 2AIQB@1|root,31972@2|Bacteria,1U866@1239|Firmicutes,4II3R@91061|Bacilli,3FAKI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01808 543734.LCABL_25620 1.88e-182 508.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli,3F3VI@33958|Lactobacillaceae 91061|Bacilli K LytTr DNA-binding domain plnD - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg AFLMLIMI_01809 543734.LCABL_25610 1.39e-166 469.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 AFLMLIMI_01810 568703.LGG_02387 2.01e-23 102.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4HH4V@91061|Bacilli 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein comD - 2.7.13.3 ko:K07706,ko:K12294 ko02020,ko02024,map02020,map02024 M00495,M00496 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 AFLMLIMI_01812 1423816.BACQ01000056_gene2171 0.0 1286.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F3QF@33958|Lactobacillaceae 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.112.1,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 AFLMLIMI_01813 543734.LCABL_25570 9.33e-309 844.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli,3F5W4@33958|Lactobacillaceae 91061|Bacilli M Transport protein ComB mesE - - ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1,8.A.1.4.2 - - HlyD_3 AFLMLIMI_01814 543734.LCABL_25560 5.75e-72 216.0 2BTF9@1|root,32NMI@2|Bacteria,1U8E8@1239|Firmicutes,4IIC5@91061|Bacilli,3FAW0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01816 543734.LCABL_25530 0.0 874.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,4HU4D@91061|Bacilli,3F4FR@33958|Lactobacillaceae 91061|Bacilli S Putative threonine/serine exporter - - - - - - - - - - - - ThrE,ThrE_2 AFLMLIMI_01817 543734.LCABL_25520 2.45e-59 183.0 COG1476@1|root,COG1476@2|Bacteria,1UM07@1239|Firmicutes,4ITNH@91061|Bacilli,3F86R@33958|Lactobacillaceae 91061|Bacilli K TRANSCRIPTIONal spiA - - - - - - - - - - - EntA_Immun AFLMLIMI_01818 543734.LCABL_25510 2.14e-58 181.0 2DEZ9@1|root,2ZPV3@2|Bacteria,1W247@1239|Firmicutes,4I0IP@91061|Bacilli 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun AFLMLIMI_01819 543734.LCABL_25500 6.69e-61 187.0 2DEZ9@1|root,2ZPV3@2|Bacteria,1W247@1239|Firmicutes,4I0IP@91061|Bacilli,3F8UH@33958|Lactobacillaceae 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun AFLMLIMI_01820 543734.LCABL_25490 1.36e-172 483.0 2AG9B@1|root,30AYZ@2|Bacteria,1U7AB@1239|Firmicutes,4IH59@91061|Bacilli,3F976@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01821 568703.LGG_02378 6.77e-81 251.0 2AG9B@1|root,30AYZ@2|Bacteria,1U7AB@1239|Firmicutes,4IH59@91061|Bacilli,3F976@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01822 543734.LCABL_25470 2.05e-72 217.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,3F7N2@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR AFLMLIMI_01823 543734.LCABL_25460 1.45e-143 405.0 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HH0D@91061|Bacilli,3F84P@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AFLMLIMI_01824 543734.LCABL_25450 9.85e-263 718.0 COG1073@1|root,COG1073@2|Bacteria,1UF81@1239|Firmicutes,4HI1Q@91061|Bacilli,3FBVJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 AFLMLIMI_01825 543734.LCABL_25440 7.65e-293 798.0 COG3410@1|root,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,4HBI0@91061|Bacilli,3F47M@33958|Lactobacillaceae 91061|Bacilli N Uncharacterized conserved protein (DUF2075) - - - ko:K09384 - - - - ko00000 - - - DUF2075,GIY-YIG AFLMLIMI_01826 1423816.BACQ01000072_gene2585 3.13e-133 377.0 2AYWY@1|root,31R2N@2|Bacteria,1UPXG@1239|Firmicutes,4IVCM@91061|Bacilli,3F66A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01827 543734.LCABL_25420 0.0 1967.0 COG4932@1|root,COG4932@2|Bacteria,1VRZM@1239|Firmicutes,4HTFC@91061|Bacilli,3F8GT@33958|Lactobacillaceae 91061|Bacilli M domain protein - - - - - - - - - - - - - AFLMLIMI_01828 543734.LCABL_25410 2.03e-307 839.0 2EZ87@1|root,33SE3@2|Bacteria,1UM06@1239|Firmicutes,4ITNG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01829 543734.LCABL_25400 0.0 1024.0 COG4932@1|root,COG4932@2|Bacteria,1UY9B@1239|Firmicutes,4HW31@91061|Bacilli,3F6KV@33958|Lactobacillaceae 91061|Bacilli M Cna protein B-type domain - - - - - - - - - - - - GramPos_pilinD1 AFLMLIMI_01830 543734.LCABL_25390 1.56e-189 527.0 COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,4HG4C@91061|Bacilli,3FCAD@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase AFLMLIMI_01832 543734.LCABL_25380 2.79e-295 805.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - AFLMLIMI_01833 1423732.BALS01000031_gene63 9e-56 181.0 29Q5T@1|root,30B4Q@2|Bacteria,1U7IZ@1239|Firmicutes,4IHFS@91061|Bacilli,3F9SF@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01835 543734.LCABL_25360 3.82e-191 531.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli,3F4E1@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase AFLMLIMI_01836 543734.LCABL_25350 1.9e-278 764.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli,3F3W7@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh AFLMLIMI_01837 543734.LCABL_25340 1.21e-286 784.0 COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,4HFIF@91061|Bacilli,3F5PJ@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 AFLMLIMI_01838 543734.LCABL_25330 5.02e-52 164.0 2DKSV@1|root,30APG@2|Bacteria,1U6Y5@1239|Firmicutes,4IGSB@91061|Bacilli,3F8PU@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01839 543734.LCABL_25320 1.5e-44 144.0 29PRZ@1|root,30AQ7@2|Bacteria,1U6Z6@1239|Firmicutes,4IGTF@91061|Bacilli,3F8RC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01841 543734.LCABL_25250 1.59e-28 103.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like yhjA - - - - - - - - - - - CsbD AFLMLIMI_01842 543734.LCABL_25240 2.84e-263 721.0 COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,4HAU5@91061|Bacilli,3F3N3@33958|Lactobacillaceae 91061|Bacilli C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases lctO - 1.13.12.4 ko:K00467,ko:K10530 ko00620,map00620 - R00319 RC01312 ko00000,ko00001,ko01000 - - - FMN_dh AFLMLIMI_01843 543734.LCABL_25230 5.25e-61 187.0 294CX@1|root,2ZRSX@2|Bacteria,1W32Y@1239|Firmicutes,4I1C7@91061|Bacilli,3F85H@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01844 543734.LCABL_25220 9.11e-261 715.0 COG4292@1|root,COG4292@2|Bacteria,1VAA8@1239|Firmicutes,4IRU7@91061|Bacilli,3FBQ1@33958|Lactobacillaceae 91061|Bacilli S Bacterial low temperature requirement A protein (LtrA) - - - - - - - - - - - - LtrA AFLMLIMI_01846 543734.LCABL_25210 1.19e-158 444.0 COG0588@1|root,COG0588@2|Bacteria,1V2UT@1239|Firmicutes,4HGRK@91061|Bacilli,3F443@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA1 - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 AFLMLIMI_01847 543734.LCABL_25200 8.84e-120 344.0 COG0517@1|root,COG0517@2|Bacteria,1TRZD@1239|Firmicutes,4HC4C@91061|Bacilli,3F6K8@33958|Lactobacillaceae 91061|Bacilli K Domain in cystathionine beta-synthase and other proteins. ccpN GO:0006355,GO:0007154,GO:0007584,GO:0008150,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0042221,GO:0045013,GO:0045892,GO:0045934,GO:0045990,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - CBS,HTH_11 AFLMLIMI_01848 543734.LCABL_25190 0.0 1696.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4HBU2@91061|Bacilli,3FBUR@33958|Lactobacillaceae 91061|Bacilli G Belongs to the PEP-utilizing enzyme family ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N AFLMLIMI_01849 543734.LCABL_25180 0.0 1332.0 COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,4HA8Z@91061|Bacilli,3F4CU@33958|Lactobacillaceae 91061|Bacilli P Transport of potassium into the cell kup - - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans AFLMLIMI_01850 543734.LCABL_25170 6.49e-213 587.0 COG1131@1|root,COG1131@2|Bacteria,1TQA2@1239|Firmicutes,4HEU0@91061|Bacilli,3FC3N@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_01851 543734.LCABL_25160 2.13e-276 757.0 28MM7@1|root,2Z8B9@2|Bacteria,1UJ2G@1239|Firmicutes,4ISZP@91061|Bacilli,3FBU3@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - AFLMLIMI_01852 543734.LCABL_25150 7.37e-252 692.0 28MJI@1|root,2ZAW0@2|Bacteria,1UZZX@1239|Firmicutes,4HCUA@91061|Bacilli,3F5KU@33958|Lactobacillaceae 91061|Bacilli - - - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - AFLMLIMI_01853 543734.LCABL_25140 0.0 901.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F49B@33958|Lactobacillaceae 91061|Bacilli E Peptidase C1-like family pepC - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 AFLMLIMI_01854 543734.LCABL_25130 0.0 883.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli,3F3QA@33958|Lactobacillaceae 91061|Bacilli E aminopeptidase pepE - 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 AFLMLIMI_01855 543734.LCABL_25120 5.93e-93 270.0 COG3152@1|root,COG3152@2|Bacteria,1VZ1N@1239|Firmicutes,4HY6Y@91061|Bacilli,3FCFB@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 AFLMLIMI_01856 543734.LCABL_25110 1.22e-67 204.0 COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli,3F80F@33958|Lactobacillaceae 91061|Bacilli S GCN5-related N-acetyl-transferase yjdJ - - ko:K06975 - - - - ko00000 - - - Acetyltransf_CG AFLMLIMI_01857 543734.LCABL_25100 4.85e-130 369.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli,3FB45@33958|Lactobacillaceae 91061|Bacilli F dUTPase dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase AFLMLIMI_01858 543734.LCABL_25090 0.0 879.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,3F3W8@33958|Lactobacillaceae 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI AFLMLIMI_01859 543734.LCABL_25080 5.49e-261 716.0 COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,3F46T@33958|Lactobacillaceae 91061|Bacilli S domain protein yacL GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - TRAM AFLMLIMI_01860 543734.LCABL_25070 2.13e-101 303.0 COG1396@1|root,COG1396@2|Bacteria,1U7HF@1239|Firmicutes,4IHE2@91061|Bacilli,3F9PR@33958|Lactobacillaceae 91061|Bacilli K sequence-specific DNA binding - - - - - - - - - - - - - AFLMLIMI_01861 543734.LCABL_25060 4.17e-204 565.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli,3F3YW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_01862 543734.LCABL_25050 2.63e-168 472.0 COG1277@1|root,COG1277@2|Bacteria,1V1GX@1239|Firmicutes,4HG2P@91061|Bacilli,3F52P@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2,ABC2_membrane_4 AFLMLIMI_01863 543734.LCABL_25040 9.99e-288 788.0 COG4932@1|root,COG4932@2|Bacteria,1UWF2@1239|Firmicutes,4HGU0@91061|Bacilli,3F6D1@33958|Lactobacillaceae 91061|Bacilli M MucBP domain inlJ - - - - - - - - - - - DUF285,Gram_pos_anchor,MucBP AFLMLIMI_01864 543734.LCABL_24990 5.31e-82 243.0 COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,4HJDB@91061|Bacilli,3F8MP@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor - - - - - - - - - - - - GntR AFLMLIMI_01865 543734.LCABL_24980 5.11e-222 614.0 COG4194@1|root,COG4194@2|Bacteria,1UY2R@1239|Firmicutes,4HEEQ@91061|Bacilli,3F7N8@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - DUF1648 AFLMLIMI_01866 543734.LCABL_24960 1.86e-145 413.0 COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,4HEYB@91061|Bacilli,3F7XI@33958|Lactobacillaceae 91061|Bacilli S Putative membrane peptidase family (DUF2324) yhfC - - - - - - - - - - - DUF2324 AFLMLIMI_01867 543734.LCABL_24950 1.21e-182 509.0 COG1737@1|root,COG1737@2|Bacteria,1UYAM@1239|Firmicutes,4HVUK@91061|Bacilli,3FC4F@33958|Lactobacillaceae 91061|Bacilli K SIS domain - - - - - - - - - - - - HTH_6,SIS AFLMLIMI_01868 543734.LCABL_24940 3.02e-152 428.0 COG0120@1|root,COG0120@2|Bacteria,1W0HS@1239|Firmicutes,4HZEY@91061|Bacilli,3F757@33958|Lactobacillaceae 91061|Bacilli G Ribose 5-phosphate isomerase A (phosphoriboisomerase A) rpiA1 - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A AFLMLIMI_01869 543734.LCABL_24930 6.68e-237 651.0 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,3F4XH@33958|Lactobacillaceae 91061|Bacilli S Oxidoreductase family, NAD-binding Rossmann fold XK27_10475 - - - - - - - - - - - GFO_IDH_MocA AFLMLIMI_01870 543734.LCABL_24920 0.0 969.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,3F3PR@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c AFLMLIMI_01872 543734.LCABL_24900 2.65e-139 393.0 29Q7Y@1|root,30B6Z@2|Bacteria,1U7NE@1239|Firmicutes,4IHJP@91061|Bacilli,3F9Y4@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01873 543734.LCABL_24890 0.0 907.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,4H9UU@91061|Bacilli,3F4AD@33958|Lactobacillaceae 91061|Bacilli C FAD linked oxidases, C-terminal domain loxD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 AFLMLIMI_01874 543734.LCABL_24880 0.0 947.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli,3F4K7@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g AFLMLIMI_01875 543734.LCABL_24870 4.83e-98 285.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli,3F6HS@33958|Lactobacillaceae 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 AFLMLIMI_01876 543734.LCABL_24860 2.21e-181 505.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,3F3TD@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind AFLMLIMI_01877 543734.LCABL_24850 5.04e-127 361.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli,3F5KC@33958|Lactobacillaceae 91061|Bacilli S YacP-like NYN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP AFLMLIMI_01879 543734.LCABL_24840 1.73e-247 680.0 COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,3F4KZ@33958|Lactobacillaceae 91061|Bacilli C Luciferase-like monooxygenase XK27_00915 - - - - - - - - - - - Bac_luciferase AFLMLIMI_01880 543734.LCABL_24830 2.69e-157 441.0 COG2085@1|root,COG2085@2|Bacteria,1UXZM@1239|Firmicutes,4HDRH@91061|Bacilli,3FB9A@33958|Lactobacillaceae 91061|Bacilli S Rossmann-like domain - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored AFLMLIMI_01882 543734.LCABL_24810 7.41e-229 630.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.30,2.5.1.83 ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 - R09245,R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt AFLMLIMI_01883 543734.LCABL_24800 1.03e-127 364.0 COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,4HG1H@91061|Bacilli,3F3R8@33958|Lactobacillaceae 91061|Bacilli S Heptaprenyl diphosphate synthase component I hepA - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - Hpre_diP_synt_I AFLMLIMI_01884 543734.LCABL_24790 2.76e-104 301.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HMR5@91061|Bacilli,3F7R1@33958|Lactobacillaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II AFLMLIMI_01885 543734.LCABL_24780 0.0 1250.0 COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,3F4N1@33958|Lactobacillaceae 91061|Bacilli C NADH dehydrogenase ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DoxX,Pyr_redox_2 AFLMLIMI_01886 543734.LCABL_24770 6.86e-187 523.0 COG4939@1|root,COG4939@2|Bacteria,1V2YY@1239|Firmicutes,4HGMF@91061|Bacilli,3FBKH@33958|Lactobacillaceae 91061|Bacilli S FMN_bind cad - - ko:K20379 ko02024,map02024 - - - ko00000,ko00001 - - - FMN_bind AFLMLIMI_01887 543734.LCABL_24760 8.97e-252 691.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli,3FB4B@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE AFLMLIMI_01888 543734.LCABL_24750 4.73e-214 592.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F6SN@33958|Lactobacillaceae 91061|Bacilli M UbiA prenyltransferase family menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA AFLMLIMI_01889 543734.LCABL_24740 4.58e-220 608.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA AFLMLIMI_01890 568703.LGG_02301 4.4e-29 103.0 COG0267@1|root,COG0267@2|Bacteria,1VFTQ@1239|Firmicutes,4HR5Q@91061|Bacilli,3F83F@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 AFLMLIMI_01891 543734.LCABL_24730 2.09e-30 107.0 COG0690@1|root,COG0690@2|Bacteria,1VK48@1239|Firmicutes,4HR1W@91061|Bacilli,3F86Y@33958|Lactobacillaceae 91061|Bacilli U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE AFLMLIMI_01892 543734.LCABL_24720 2.29e-130 370.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli,3F55W@33958|Lactobacillaceae 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG AFLMLIMI_01893 543734.LCABL_24710 9.91e-205 566.0 COG4814@1|root,COG4814@2|Bacteria,1V910@1239|Firmicutes,4HF90@91061|Bacilli,3F4RX@33958|Lactobacillaceae 91061|Bacilli S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 AFLMLIMI_01894 543734.LCABL_24700 3.1e-101 293.0 COG3613@1|root,COG3613@2|Bacteria,1U5KZ@1239|Firmicutes,4IFBV@91061|Bacilli,3F74G@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr AFLMLIMI_01895 543734.LCABL_24690 0.0 1520.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,4HFF1@91061|Bacilli,3F3VU@33958|Lactobacillaceae 91061|Bacilli F ribonucleoside-triphosphate reductase activity rtpR - 1.17.4.2 ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02014,R02020,R02022,R02023,R04315 RC00013,RC00613 ko00000,ko00001,ko00002,ko01000 - - - Ribonuc_red_lgC AFLMLIMI_01896 543734.LCABL_24680 4.31e-83 246.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli,3F6AM@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 AFLMLIMI_01897 543734.LCABL_24670 6.47e-124 354.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli,3F5H7@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt AFLMLIMI_01898 543734.LCABL_24660 5.08e-119 341.0 COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,4IS1C@91061|Bacilli,3FBQY@33958|Lactobacillaceae 91061|Bacilli S Cobalamin adenosyltransferase yvqK - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans AFLMLIMI_01899 543734.LCABL_24650 6.01e-87 255.0 COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,3F79K@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DU1801) frataxin - - ko:K05937 - - - - ko00000 - - - DUF1801 AFLMLIMI_01900 543734.LCABL_24640 0.0 926.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli,3F4UM@33958|Lactobacillaceae 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase,Gram_pos_anchor AFLMLIMI_01901 543734.LCABL_24630 0.0 1695.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli,3F4E0@33958|Lactobacillaceae 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase AFLMLIMI_01902 543734.LCABL_24620 6.87e-93 271.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,3F64I@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N AFLMLIMI_01903 543734.LCABL_24610 1.89e-158 444.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,3F3VQ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 AFLMLIMI_01904 543734.LCABL_24600 0.0 903.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,3F47F@33958|Lactobacillaceae 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh AFLMLIMI_01905 543734.LCABL_24590 6.18e-233 645.0 COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,4IS86@91061|Bacilli,3FBXF@33958|Lactobacillaceae 91061|Bacilli G Sugar (and other) transporter yceI - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr AFLMLIMI_01906 543734.LCABL_24590 1.33e-29 114.0 COG2271@1|root,COG2271@2|Bacteria,1UHSG@1239|Firmicutes,4IS86@91061|Bacilli,3FBXF@33958|Lactobacillaceae 91061|Bacilli G Sugar (and other) transporter yceI - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - MFS_1,Sugar_tr AFLMLIMI_01907 1423816.BACQ01000053_gene2060 4.02e-86 257.0 29Q17@1|root,30AZR@2|Bacteria,1U7BG@1239|Firmicutes,4IH6H@91061|Bacilli,3F99Z@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01908 543734.LCABL_24570 4.96e-199 551.0 COG0454@1|root,COG0456@2|Bacteria,1V42X@1239|Firmicutes,4HI1M@91061|Bacilli,3F6TI@33958|Lactobacillaceae 91061|Bacilli K acetyltransferase - - - - - - - - - - - - - AFLMLIMI_01909 543734.LCABL_24560 1.92e-283 776.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli,3F3T5@33958|Lactobacillaceae 91061|Bacilli EGP Transporter, major facilitator family protein mdtG - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr AFLMLIMI_01910 543734.LCABL_24550 7.23e-108 311.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli,3F4S4@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 AFLMLIMI_01911 543734.LCABL_24540 1.37e-74 224.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli,3F6YA@33958|Lactobacillaceae 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N AFLMLIMI_01912 543734.LCABL_24530 1.15e-203 565.0 COG0760@1|root,COG0760@2|Bacteria,1VT0K@1239|Firmicutes,4I4BP@91061|Bacilli,3F4RW@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins - - 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 AFLMLIMI_01913 543734.LCABL_24520 0.0 3387.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,3F3M5@33958|Lactobacillaceae 91061|Bacilli O Belongs to the peptidase S8 family prtB - 3.4.21.96 ko:K01361 - - - - ko00000,ko01000,ko01002,ko03110 - - - FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5 AFLMLIMI_01914 543734.LCABL_24510 1.49e-225 621.0 COG1609@1|root,COG1609@2|Bacteria,1TQSQ@1239|Firmicutes,4HBNR@91061|Bacilli,3F4YI@33958|Lactobacillaceae 91061|Bacilli K lacI family ccpB - - - - - - - - - - - LacI,Peripla_BP_1 AFLMLIMI_01915 1423816.BACQ01000053_gene2052 8.11e-60 187.0 2BJY6@1|root,32EAT@2|Bacteria,1U7NB@1239|Firmicutes,4IHJK@91061|Bacilli,3F9XZ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01916 543734.LCABL_24490 0.0 1676.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,3F3PY@33958|Lactobacillaceae 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM AFLMLIMI_01917 543734.LCABL_24480 2.74e-138 391.0 COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,4HHCA@91061|Bacilli,3F4NU@33958|Lactobacillaceae 91061|Bacilli J Methyltransferase rsmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS AFLMLIMI_01918 543734.LCABL_24470 9.05e-67 203.0 2EMDH@1|root,33F2E@2|Bacteria,1VKX3@1239|Firmicutes,4HR5Y@91061|Bacilli,3F709@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01919 543734.LCABL_24460 4.38e-118 337.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,3F6IS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam AFLMLIMI_01920 543734.LCABL_24450 0.0 1092.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 AFLMLIMI_01921 543734.LCABL_24440 7e-49 157.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,3F7F3@33958|Lactobacillaceae 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd AFLMLIMI_01922 543734.LCABL_24430 1.26e-139 394.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,3F4JQ@33958|Lactobacillaceae 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 AFLMLIMI_01923 568703.LGG_02263 2.95e-46 149.0 2DKQT@1|root,30ADD@2|Bacteria,1U6HS@1239|Firmicutes,4IGA3@91061|Bacilli,3F7Y1@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2508) - - - - - - - - - - - - DUF2508 AFLMLIMI_01924 543734.LCABL_24410 2.06e-150 423.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,3F4JR@33958|Lactobacillaceae 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin AFLMLIMI_01925 543734.LCABL_24400 1.14e-69 210.0 COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3F6VW@33958|Lactobacillaceae 91061|Bacilli S Cyclic-di-AMP receptor yaaQ - - - - - - - - - - - CdAMP_rec AFLMLIMI_01926 543734.LCABL_24390 6.53e-223 615.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,3F50D@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C AFLMLIMI_01927 543734.LCABL_24380 7.92e-76 226.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli,3F864@33958|Lactobacillaceae 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB AFLMLIMI_01928 543734.LCABL_24370 1.49e-192 535.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3F4AI@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase AFLMLIMI_01929 543734.LCABL_24360 3.17e-184 511.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli,3F41B@33958|Lactobacillaceae 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE AFLMLIMI_01931 1235801.C822_00413 1.21e-43 150.0 29XQD@1|root,30JG1@2|Bacteria,1TVFA@1239|Firmicutes,4I1PS@91061|Bacilli,3FAZJ@33958|Lactobacillaceae 91061|Bacilli S Phospholipase A2 - - - - - - - - - - - - Phospholip_A2_1 AFLMLIMI_01932 543734.LCABL_24350 1.19e-229 632.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli,3F3XA@33958|Lactobacillaceae 91061|Bacilli EJ Asparaginase ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase AFLMLIMI_01933 543734.LCABL_24340 2.42e-117 336.0 COG3275@1|root,COG3275@2|Bacteria,1VB87@1239|Firmicutes,4ISET@91061|Bacilli,3FBSH@33958|Lactobacillaceae 91061|Bacilli T ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt AFLMLIMI_01934 1423732.BALS01000008_gene801 4.18e-96 285.0 2AQ5J@1|root,31FAY@2|Bacteria,1U7CF@1239|Firmicutes,4IH7T@91061|Bacilli,3F9CK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01935 543734.LCABL_24320 3.82e-168 470.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli,3F3WV@33958|Lactobacillaceae 91061|Bacilli O Universal bacterial protein YeaZ yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 AFLMLIMI_01936 543734.LCABL_24310 8.44e-130 368.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HIKU@91061|Bacilli,3F522@33958|Lactobacillaceae 91061|Bacilli K Ribosomal-protein-alanine acetyltransferase rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 AFLMLIMI_01937 543734.LCABL_24300 5.99e-243 667.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli,3F4AX@33958|Lactobacillaceae 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 AFLMLIMI_01938 543734.LCABL_24290 3.12e-68 207.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F6GU@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB AFLMLIMI_01939 543734.LCABL_24280 0.0 1249.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn AFLMLIMI_01940 543734.LCABL_24270 1.1e-151 426.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,3F40G@33958|Lactobacillaceae 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N AFLMLIMI_01941 543734.LCABL_24260 4.97e-81 240.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,3F7AX@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR AFLMLIMI_01942 543734.LCABL_24250 1.39e-202 561.0 COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,4HA3P@91061|Bacilli,3FC3A@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K01990,ko:K16921 ko02010,map02010 M00254,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_01943 543734.LCABL_24240 1.4e-221 613.0 2DKT0@1|root,30APV@2|Bacteria,1U6YM@1239|Firmicutes,4IGSU@91061|Bacilli,3F8QM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01944 543734.LCABL_24230 4.11e-251 689.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr AFLMLIMI_01945 543734.LCABL_24220 6.1e-143 404.0 COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,3F5JU@33958|Lactobacillaceae 91061|Bacilli S CAAX protease self-immunity ydiL - - ko:K07052 - - - - ko00000 - - - Abi AFLMLIMI_01946 543734.LCABL_24210 1.7e-59 183.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,3F7CZ@33958|Lactobacillaceae 91061|Bacilli O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 AFLMLIMI_01947 543734.LCABL_24200 0.0 1016.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli,3F3MM@33958|Lactobacillaceae 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 AFLMLIMI_01948 543734.LCABL_24190 5.32e-75 224.0 2EUB0@1|root,33MTD@2|Bacteria,1W3MW@1239|Firmicutes,4HZUX@91061|Bacilli,3F7TK@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) - - - - - - - - - - - - DUF1827 AFLMLIMI_01949 543734.LCABL_24180 0.0 1146.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli,3F44Y@33958|Lactobacillaceae 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 AFLMLIMI_01950 543734.LCABL_24170 0.0 1653.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli,3F4A5@33958|Lactobacillaceae 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V AFLMLIMI_01951 543734.LCABL_24160 0.0 1268.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,3F3PK@33958|Lactobacillaceae 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C AFLMLIMI_01952 543734.LCABL_24150 4.8e-128 364.0 COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4HIMK@91061|Bacilli,3F65C@33958|Lactobacillaceae 91061|Bacilli D nucleoside-triphosphate diphosphatase activity maf GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - ko:K06287 - - - - ko00000 - - - Maf AFLMLIMI_01953 568703.LGG_02232 8.38e-80 240.0 2C9UQ@1|root,309VR@2|Bacteria,1U5T4@1239|Firmicutes,4IFH1@91061|Bacilli,3F6FU@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4811) - - - - - - - - - - - - DUF4811 AFLMLIMI_01954 543734.LCABL_24130 0.0 889.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily ycnB - - - - - - - - - - - MFS_1 AFLMLIMI_01955 543734.LCABL_24120 0.0 894.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3TX@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain yhdP - - - - - - - - - - - CBS,CorC_HlyC,DUF21 AFLMLIMI_01956 543734.LCABL_24110 2.13e-173 484.0 COG4295@1|root,COG4295@2|Bacteria,1VAHN@1239|Firmicutes,4HY6J@91061|Bacilli,3FBBD@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2263) - - - - - - - - - - - - DUF2263 AFLMLIMI_01957 543734.LCABL_24100 1.16e-152 428.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase AFLMLIMI_01958 543734.LCABL_24090 1.45e-133 391.0 COG3103@1|root,COG3103@2|Bacteria,1VB6H@1239|Firmicutes,4I1GZ@91061|Bacilli,3F66H@33958|Lactobacillaceae 91061|Bacilli T Sh3 type 3 domain protein - - - - - - - - - - - - LysM,SLAP AFLMLIMI_01959 543734.LCABL_24080 2.29e-131 372.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 AFLMLIMI_01961 543734.LCABL_24050 1.08e-145 411.0 COG0702@1|root,COG0702@2|Bacteria,1UJSC@1239|Firmicutes,4HCVT@91061|Bacilli,3F4ZZ@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10 AFLMLIMI_01962 543734.LCABL_24040 8.6e-250 685.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,3F42F@33958|Lactobacillaceae 91061|Bacilli E alcohol dehydrogenase adh2 - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N AFLMLIMI_01963 543734.LCABL_24030 2.59e-107 309.0 COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,4HN5X@91061|Bacilli,3F7H7@33958|Lactobacillaceae 91061|Bacilli C Flavodoxin - - - - - - - - - - - - Flavodoxin_4 AFLMLIMI_01964 543734.LCABL_24020 5.77e-93 271.0 COG0789@1|root,COG0789@2|Bacteria,1VAAP@1239|Firmicutes,4HKZ9@91061|Bacilli,3F6JI@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, mercury resistance adhR - - - - - - - - - - - MerR,MerR-DNA-bind,MerR_1 AFLMLIMI_01965 543734.LCABL_24010 7.09e-113 325.0 COG1268@1|root,COG1268@2|Bacteria,1VAAD@1239|Firmicutes,4HI8T@91061|Bacilli,3F6YG@33958|Lactobacillaceae 91061|Bacilli S BioY family bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY AFLMLIMI_01966 543734.LCABL_23990 1.54e-84 249.0 29PE3@1|root,30AC9@2|Bacteria,1U6GD@1239|Firmicutes,4IG8H@91061|Bacilli,3F7V6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01967 543734.LCABL_23980 3.87e-286 780.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,3F5I3@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF1730) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 AFLMLIMI_01968 543734.LCABL_23970 1.29e-186 518.0 COG2365@1|root,COG2365@2|Bacteria,1VBGE@1239|Firmicutes,4HN6J@91061|Bacilli,3FBJY@33958|Lactobacillaceae 91061|Bacilli T Tyrosine phosphatase family ptp3 - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - Y_phosphatase3 AFLMLIMI_01969 568703.LGG_02218 3.25e-74 223.0 29Q5Z@1|root,30B4V@2|Bacteria,1U7J6@1239|Firmicutes,4IHG0@91061|Bacilli,3F9SW@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_31 AFLMLIMI_01970 543734.LCABL_23950 3.91e-100 290.0 COG0589@1|root,COG0589@2|Bacteria,1VEJR@1239|Firmicutes,4HNHG@91061|Bacilli,3F4Z0@33958|Lactobacillaceae 91061|Bacilli T universal stress protein usp5 - - - - - - - - - - - Usp AFLMLIMI_01971 543734.LCABL_23940 3.45e-144 406.0 COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,3F5KA@33958|Lactobacillaceae 91061|Bacilli L glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco AFLMLIMI_01972 543734.LCABL_23930 1.72e-213 590.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli,3F423@33958|Lactobacillaceae 91061|Bacilli EG EamA-like transporter family - - - - - - - - - - - - EamA AFLMLIMI_01973 543734.LCABL_23910 6.71e-34 116.0 29PYW@1|root,30AXC@2|Bacteria,1U786@1239|Firmicutes,4IH32@91061|Bacilli,3F93Q@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01974 543734.LCABL_23900 1.22e-112 323.0 2CCK1@1|root,309S4@2|Bacteria,1U5KG@1239|Firmicutes,4IFBA@91061|Bacilli,3F64Y@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01975 543734.LCABL_23890 6.98e-53 166.0 2900D@1|root,30NTF@2|Bacteria,1U66C@1239|Firmicutes,4IFWI@91061|Bacilli,3F8DT@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01976 543734.LCABL_23880 6.24e-244 670.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli,3F5RC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase AFLMLIMI_01977 543734.LCABL_23870 2.35e-303 828.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,3F45P@33958|Lactobacillaceae 91061|Bacilli F pyrimidine-nucleoside phosphorylase pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C AFLMLIMI_01978 543734.LCABL_23860 0.0 962.0 COG1271@1|root,COG1271@2|Bacteria,1TRH4@1239|Firmicutes,4HA19@91061|Bacilli,3F4MJ@33958|Lactobacillaceae 91061|Bacilli C ubiquinol oxidase cydA - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I AFLMLIMI_01979 543734.LCABL_23850 2.5e-233 643.0 COG1294@1|root,COG1294@2|Bacteria,1TRYV@1239|Firmicutes,4H9KF@91061|Bacilli,3F40S@33958|Lactobacillaceae 91061|Bacilli C Cytochrome d ubiquinol oxidase subunit II cydB - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - iYO844.BSU38750 Cyt_bd_oxida_II AFLMLIMI_01980 543734.LCABL_23840 0.0 1125.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HAN0@91061|Bacilli,3F451@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD cydC GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran AFLMLIMI_01981 543734.LCABL_23830 0.0 1126.0 COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4HAAB@91061|Bacilli,3F4PG@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC cydD - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran AFLMLIMI_01982 543734.LCABL_23820 7.52e-65 198.0 2DZIG@1|root,32VBI@2|Bacteria,1VIUB@1239|Firmicutes,4HRZP@91061|Bacilli,3F7EN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF4870 AFLMLIMI_01983 543734.LCABL_23810 3.22e-82 243.0 COG5294@1|root,COG5294@2|Bacteria,1VF0I@1239|Firmicutes,4HPC2@91061|Bacilli,3F83V@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 AFLMLIMI_01984 543734.LCABL_23800 1.03e-278 762.0 COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,4HITC@91061|Bacilli,3F50M@33958|Lactobacillaceae 91061|Bacilli S Membrane - - - - - - - - - - - - - AFLMLIMI_01985 543734.LCABL_23790 2.79e-182 508.0 29PFB@1|root,30ADG@2|Bacteria,1U6HW@1239|Firmicutes,4IGA7@91061|Bacilli,3F7Y8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_01986 568703.LGG_02198 3.88e-208 582.0 COG3409@1|root,COG3409@2|Bacteria,1V2YC@1239|Firmicutes,4HFNB@91061|Bacilli,3F6TH@33958|Lactobacillaceae 91061|Bacilli M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - AFLMLIMI_01987 543734.LCABL_23710 1.23e-95 278.0 COG5341@1|root,COG5341@2|Bacteria,1VCR8@1239|Firmicutes,4HKP0@91061|Bacilli,3FBC0@33958|Lactobacillaceae 91061|Bacilli S NusG domain II - - - - - - - - - - - - NusG_II AFLMLIMI_01988 543734.LCABL_23700 0.0 1095.0 COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,4HCDA@91061|Bacilli,3F4VY@33958|Lactobacillaceae 91061|Bacilli CO ABC transporter transmembrane region cydD1 - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran,DUF454 AFLMLIMI_01989 543734.LCABL_23690 0.0 1010.0 COG1132@1|root,COG1132@2|Bacteria,1UHQP@1239|Firmicutes,4HC57@91061|Bacilli,3F5XV@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region msbA9 - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran AFLMLIMI_01990 543734.LCABL_23680 4.16e-199 552.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli,3F4SJ@33958|Lactobacillaceae 91061|Bacilli K CAT RNA binding domain bglG4 - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD AFLMLIMI_01991 543734.LCABL_23670 0.0 1135.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system bglP - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AFLMLIMI_01992 543734.LCABL_23660 0.0 1009.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglH - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AFLMLIMI_01993 543734.LCABL_23650 2.36e-125 357.0 COG1309@1|root,COG1309@2|Bacteria,1UVV7@1239|Firmicutes,4I435@91061|Bacilli,3F8HZ@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - ko:K18939 - M00715 - - ko00000,ko00002,ko03000 - - - TetR_N AFLMLIMI_01994 543734.LCABL_23630 2.64e-316 864.0 COG0477@1|root,COG2814@2|Bacteria,1TPRN@1239|Firmicutes,4H9VV@91061|Bacilli,3F4A2@33958|Lactobacillaceae 91061|Bacilli U Belongs to the major facilitator superfamily lmrB - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 AFLMLIMI_01995 543734.LCABL_23620 0.0 889.0 COG1249@1|root,COG1249@2|Bacteria,1TS0Z@1239|Firmicutes,4HBYB@91061|Bacilli,3F3K2@33958|Lactobacillaceae 91061|Bacilli C Glutathione reductase gshR3 - 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim AFLMLIMI_01996 543734.LCABL_23610 0.0 974.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepD3 - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AFLMLIMI_01997 543734.LCABL_23600 3.4e-82 243.0 2E6A2@1|root,3182Z@2|Bacteria,1V931@1239|Firmicutes,4HNND@91061|Bacilli,3F77F@33958|Lactobacillaceae 91061|Bacilli S Coenzyme PQQ synthesis protein D (PqqD) - - - - - - - - - - - - PqqD AFLMLIMI_01998 1423732.BALS01000018_gene1802 0.0 1053.0 COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,4HB4S@91061|Bacilli,3F3KY@33958|Lactobacillaceae 91061|Bacilli S OPT oligopeptide transporter protein - - - - - - - - - - - - OPT AFLMLIMI_01999 543734.LCABL_23570 6.15e-238 655.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli,3F5KK@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C AFLMLIMI_02000 543734.LCABL_23560 1.45e-257 707.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,3F4ZR@33958|Lactobacillaceae 91061|Bacilli C Belongs to the AlaDH PNT family ald1 - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N AFLMLIMI_02001 543734.LCABL_23550 2.06e-187 520.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli,3F4FH@33958|Lactobacillaceae 91061|Bacilli IQ reductase gdh - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - - adh_short_C2 AFLMLIMI_02002 543734.LCABL_23540 1.05e-143 406.0 COG1835@1|root,COG1835@2|Bacteria,1UG9X@1239|Firmicutes,4IGYH@91061|Bacilli,3F8XZ@33958|Lactobacillaceae 91061|Bacilli I ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 AFLMLIMI_02003 543734.LCABL_23530 9.19e-209 577.0 COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,4HB36@91061|Bacilli,3F4BW@33958|Lactobacillaceae 91061|Bacilli V ABC transporter CcmA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_02004 543734.LCABL_23520 6.81e-86 253.0 COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,4HKSY@91061|Bacilli,3F78Z@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix gluconate operon transcriptional repressor ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR AFLMLIMI_02005 543734.LCABL_23510 3.71e-280 768.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3F3KA@33958|Lactobacillaceae 91061|Bacilli CP ABC-2 family transporter protein ysdA - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 AFLMLIMI_02006 543734.LCABL_23500 9.96e-212 585.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ysdB - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 AFLMLIMI_02007 543734.LCABL_23490 1.92e-283 775.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,3F48Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase AFLMLIMI_02008 543734.LCABL_23480 3.26e-226 624.0 COG0142@1|root,COG0142@2|Bacteria,1TR0U@1239|Firmicutes,4H9RH@91061|Bacilli,3F4GC@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family hepT - 2.5.1.30 ko:K00805 ko00900,ko01110,map00900,map01110 - R09247 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt AFLMLIMI_02009 543734.LCABL_23470 6.87e-203 563.0 COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,4HA68@91061|Bacilli,3F3JM@33958|Lactobacillaceae 91061|Bacilli H 1,4-dihydroxy-2-naphthoate menA - 2.5.1.74 ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116 R05617,R06858,R10757 RC02935,RC02936,RC03264 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA AFLMLIMI_02010 543734.LCABL_23460 2.89e-254 697.0 2EQYH@1|root,33II5@2|Bacteria,1VMH1@1239|Firmicutes,4HUIK@91061|Bacilli,3F5E7@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos AFLMLIMI_02011 543734.LCABL_23430 0.0 1282.0 COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,3F3NT@33958|Lactobacillaceae 91061|Bacilli E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 AFLMLIMI_02012 543734.LCABL_23420 3.28e-93 271.0 COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,4HIE1@91061|Bacilli,3FCD8@33958|Lactobacillaceae 91061|Bacilli FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT AFLMLIMI_02013 543734.LCABL_23410 6.09e-162 454.0 COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,4HHYG@91061|Bacilli,3F4J7@33958|Lactobacillaceae 91061|Bacilli S Mitochondrial biogenesis AIM24 WQ51_05710 - - - - - - - - - - - AIM24 AFLMLIMI_02014 543734.LCABL_23400 3.6e-67 204.0 2BNCG@1|root,32H06@2|Bacteria,1U7X9@1239|Firmicutes,4IHUN@91061|Bacilli,3FAAB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02015 543734.LCABL_23390 9.39e-277 757.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspC - 2.6.1.57 ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 M00024,M00025,M00034,M00040,M00525 R00694,R00734,R01731,R04467,R07396,R10845 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_02016 543734.LCABL_23380 1.68e-224 620.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,4HCIS@91061|Bacilli,3F4US@33958|Lactobacillaceae 91061|Bacilli CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family ldhD - 1.1.1.28 ko:K03778 ko00620,ko01120,map00620,map01120 - R00704 RC00044 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C AFLMLIMI_02017 543734.LCABL_23370 1.23e-221 614.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HC4N@91061|Bacilli,3FCB3@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoSR - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 AFLMLIMI_02018 568703.LGG_02158 7.64e-51 164.0 2ESCD@1|root,33JX6@2|Bacteria,1VQB2@1239|Firmicutes,4HT0C@91061|Bacilli,3F9Y6@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02019 543734.LCABL_23350 3.74e-269 748.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,4HA0C@91061|Bacilli,3F5TM@33958|Lactobacillaceae 91061|Bacilli S SPFH domain / Band 7 family floL - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot AFLMLIMI_02020 543734.LCABL_23340 0.0 867.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli,3F48V@33958|Lactobacillaceae 91061|Bacilli E Belongs to the aspartokinase family - - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 AFLMLIMI_02021 543734.LCABL_23330 1.87e-289 790.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli,3F5BM@33958|Lactobacillaceae 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 AFLMLIMI_02022 543734.LCABL_23320 0.0 984.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli,3F3UF@33958|Lactobacillaceae 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N AFLMLIMI_02023 543734.LCABL_23310 2.89e-191 533.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,3F44T@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N AFLMLIMI_02024 543734.LCABL_23300 0.0 866.0 COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,3F3S7@33958|Lactobacillaceae 91061|Bacilli S ATP-grasp enzyme yxbA - 6.3.1.12 ko:K17810 - - - - ko00000,ko01000 - - - CPSase_L_D2,Dala_Dala_lig_C AFLMLIMI_02025 543734.LCABL_23290 2.6e-96 281.0 COG0589@1|root,COG0589@2|Bacteria,1U62R@1239|Firmicutes,4IFRW@91061|Bacilli,3F6W5@33958|Lactobacillaceae 91061|Bacilli T Universal stress protein family usp1 - - - - - - - - - - - Usp AFLMLIMI_02026 543734.LCABL_23280 1.39e-176 491.0 COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,4HCPN@91061|Bacilli,3F4KV@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SfsA family sfsA - - ko:K06206 - - - - ko00000 - - - SfsA AFLMLIMI_02027 543734.LCABL_23270 9.19e-285 779.0 COG4175@1|root,COG4175@2|Bacteria,1UHNE@1239|Firmicutes,4HA9P@91061|Bacilli,3FC38@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuA - 3.6.3.32 ko:K02000 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.12 - - ABC_tran,CBS AFLMLIMI_02028 543734.LCABL_23260 5.82e-189 526.0 COG4176@1|root,COG4176@2|Bacteria,1UHRI@1239|Firmicutes,4IS7D@91061|Bacilli,3F4W7@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuB - - ko:K02001 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 AFLMLIMI_02029 543734.LCABL_23250 3.51e-216 596.0 COG2113@1|root,COG2113@2|Bacteria,1TP82@1239|Firmicutes,4H9MM@91061|Bacilli,3F4B3@33958|Lactobacillaceae 91061|Bacilli E glycine betaine gbuC - - ko:K02001,ko:K02002 ko02010,map02010 M00208 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC AFLMLIMI_02030 543734.LCABL_23230 0.0 1154.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family - - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AFLMLIMI_02031 543734.LCABL_23220 1.01e-223 616.0 COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli,3F5ND@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat AFLMLIMI_02032 543734.LCABL_23210 8.13e-85 251.0 COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,4HNK7@91061|Bacilli,3F4GH@33958|Lactobacillaceae 91061|Bacilli S Teichoic acid glycosylation protein gtcA2 - - - - - - - - - - - GtrA AFLMLIMI_02034 543734.LCABL_23200 4.31e-166 464.0 COG3764@1|root,COG3764@2|Bacteria,1V4ZG@1239|Firmicutes,4HMUE@91061|Bacilli,3FBG7@33958|Lactobacillaceae 91061|Bacilli M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase AFLMLIMI_02035 543734.LCABL_23190 4.01e-240 662.0 COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,3F46E@33958|Lactobacillaceae 91061|Bacilli K AI-2E family transporter ydbI GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport AFLMLIMI_02036 543734.LCABL_23180 8.42e-262 717.0 COG1680@1|root,COG1680@2|Bacteria,1V4BS@1239|Firmicutes,4HJRT@91061|Bacilli,3F3QN@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase pbpX - - - - - - - - - - - Beta-lactamase,SLH AFLMLIMI_02037 543734.LCABL_23170 1.09e-209 585.0 COG4640@1|root,COG4640@2|Bacteria,1VIMB@1239|Firmicutes,4HP7R@91061|Bacilli,3F7Z9@33958|Lactobacillaceae 91061|Bacilli S zinc-ribbon domain - - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 AFLMLIMI_02038 568703.LGG_02139 4.74e-30 107.0 2AWRG@1|root,31NNE@2|Bacteria,1U7XJ@1239|Firmicutes,4IHUY@91061|Bacilli,3FAAP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02039 543734.LCABL_23150 1.91e-167 467.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,3F3SK@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 AFLMLIMI_02040 543734.LCABL_23140 6.6e-106 305.0 COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,4HHQT@91061|Bacilli,3F4BS@33958|Lactobacillaceae 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX AFLMLIMI_02041 543734.LCABL_23130 0.0 1113.0 COG1132@1|root,COG1132@2|Bacteria,1TSY4@1239|Firmicutes,4HAJQ@91061|Bacilli,3FC4S@33958|Lactobacillaceae 91061|Bacilli V ABC transporter lmrA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 3.6.3.44 ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.123,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_02042 543734.LCABL_23120 1.47e-136 386.0 COG1846@1|root,COG1846@2|Bacteria,1VF51@1239|Firmicutes,4HM7R@91061|Bacilli,3F725@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 AFLMLIMI_02043 543734.LCABL_23110 2.78e-253 696.0 28USJ@1|root,2ZGWS@2|Bacteria,1W533@1239|Firmicutes,4I1UJ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - zinc_ribbon_2 AFLMLIMI_02044 543734.LCABL_23100 5.89e-215 596.0 COG0627@1|root,COG0627@2|Bacteria,1V856@1239|Firmicutes,4HVCY@91061|Bacilli,3F5Y5@33958|Lactobacillaceae 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase AFLMLIMI_02045 1423734.JCM14202_162 2.67e-13 77.0 COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,3FBEE@33958|Lactobacillaceae 91061|Bacilli S response to antibiotic tcaA - - ko:K21463 - - - - ko00000 - - - zf-ribbon_3,zinc_ribbon_2 AFLMLIMI_02046 543734.LCABL_23080 1.92e-88 260.0 COG1846@1|root,COG1846@2|Bacteria,1VMZX@1239|Firmicutes,4HMTC@91061|Bacilli,3FBM2@33958|Lactobacillaceae 91061|Bacilli K MarR family - - - ko:K18909 - M00705 - - ko00000,ko00002,ko01504,ko03000 - - - MarR,MarR_2 AFLMLIMI_02047 543734.LCABL_23070 6.7e-62 190.0 COG4367@1|root,COG4367@2|Bacteria,1VGC1@1239|Firmicutes,4HQJ6@91061|Bacilli,3F89N@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2316) - - - - - - - - - - - - DUF2316 AFLMLIMI_02048 543734.LCABL_23040 1.53e-287 785.0 COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,4H9TR@91061|Bacilli,3F4VF@33958|Lactobacillaceae 91061|Bacilli C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH AFLMLIMI_02049 543734.LCABL_23030 4.22e-245 672.0 COG2021@1|root,COG2021@2|Bacteria,1UM05@1239|Firmicutes,4ITNF@91061|Bacilli,3F97M@33958|Lactobacillaceae 91061|Bacilli E Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 AFLMLIMI_02050 543734.LCABL_23020 9.65e-95 276.0 COG0764@1|root,COG0764@2|Bacteria,1V3UN@1239|Firmicutes,4HHYD@91061|Bacilli,3F77T@33958|Lactobacillaceae 91061|Bacilli I FabA-like domain - - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA AFLMLIMI_02051 543734.LCABL_23010 2.44e-99 288.0 COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4IR3W@91061|Bacilli,3FC7M@33958|Lactobacillaceae 91061|Bacilli K Winged helix DNA-binding domain - - - - - - - - - - - - MarR AFLMLIMI_02052 543734.LCABL_23000 3.96e-226 623.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,3F3XP@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C AFLMLIMI_02053 543734.LCABL_22990 1.38e-45 147.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli,3F7ZJ@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding AFLMLIMI_02054 543734.LCABL_22980 4.56e-220 608.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli,3F4PC@33958|Lactobacillaceae 91061|Bacilli S Nitronate monooxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO AFLMLIMI_02055 543734.LCABL_22970 8.45e-210 581.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,3F3W9@33958|Lactobacillaceae 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 AFLMLIMI_02056 543734.LCABL_22960 1.67e-163 458.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,3F4RI@33958|Lactobacillaceae 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 AFLMLIMI_02057 543734.LCABL_22950 2.84e-283 775.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3F51H@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt AFLMLIMI_02058 543734.LCABL_22940 8.8e-93 272.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli,3F7M1@33958|Lactobacillaceae 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl AFLMLIMI_02059 543734.LCABL_22930 3.23e-98 285.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli,3F5EE@33958|Lactobacillaceae 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA AFLMLIMI_02060 543734.LCABL_22920 0.0 891.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,3F3PT@33958|Lactobacillaceae 91061|Bacilli I Acetyl-CoA carboxylase biotin carboxylase subunit accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 AFLMLIMI_02061 543734.LCABL_22910 8.74e-194 537.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli,3F3T6@33958|Lactobacillaceae 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans AFLMLIMI_02062 543734.LCABL_22900 3.41e-184 512.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli,3F496@33958|Lactobacillaceae 91061|Bacilli I alpha subunit accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA AFLMLIMI_02063 543734.LCABL_22890 3.95e-297 809.0 COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,4HDKI@91061|Bacilli,3F3PA@33958|Lactobacillaceae 91061|Bacilli M cyclopropane-fatty-acyl-phospholipid synthase cfa - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS AFLMLIMI_02064 543734.LCABL_22880 6.71e-208 575.0 COG0702@1|root,COG0702@2|Bacteria,1UY7W@1239|Firmicutes,4HDIS@91061|Bacilli,3F4M7@33958|Lactobacillaceae 91061|Bacilli GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA AFLMLIMI_02065 543734.LCABL_22840 0.0 1041.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,3F4UD@33958|Lactobacillaceae 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N AFLMLIMI_02066 543734.LCABL_22830 6.12e-232 639.0 COG1609@1|root,COG1609@2|Bacteria,1TRHK@1239|Firmicutes,4HB9P@91061|Bacilli,3F5FI@33958|Lactobacillaceae 91061|Bacilli K Periplasmic binding proteins and sugar binding domain of LacI family purR2 - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 AFLMLIMI_02067 543734.LCABL_22820 0.0 1150.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,3F41I@33958|Lactobacillaceae 91061|Bacilli G Alpha amylase, catalytic domain protein malL - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - Alpha-amylase,DUF3459,Malt_amylase_C AFLMLIMI_02068 1423732.BALS01000016_gene1697 0.0 1159.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli,3F458@33958|Lactobacillaceae 91061|Bacilli G phosphotransferase system pts26BCA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC AFLMLIMI_02069 543734.LCABL_22790 2.02e-270 741.0 2DSXT@1|root,32UTZ@2|Bacteria,1VRUF@1239|Firmicutes,4HTM0@91061|Bacilli,3FB9G@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - DUF998 AFLMLIMI_02070 543734.LCABL_22770 3.02e-96 284.0 2AYN8@1|root,31QSR@2|Bacteria,1V7X1@1239|Firmicutes,4HIZR@91061|Bacilli,3F859@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02071 543734.LCABL_22760 0.0 1961.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,3F50Q@33958|Lactobacillaceae 91061|Bacilli V Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII AFLMLIMI_02072 1123312.KB904581_gene1112 1.93e-252 707.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase AFLMLIMI_02073 543734.LCABL_22730 7.3e-180 514.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes 1239|Firmicutes V type I restriction modification DNA specificity domain hsdS - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S AFLMLIMI_02074 543734.LCABL_22720 4.99e-223 614.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HDHJ@91061|Bacilli,3FC9T@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase AFLMLIMI_02075 1423816.BACQ01000038_gene1593 1.15e-74 237.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4HJFT@91061|Bacilli,3F7JB@33958|Lactobacillaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S AFLMLIMI_02076 543734.LCABL_22700 0.0 1362.0 COG1479@1|root,COG1479@2|Bacteria,1TPAT@1239|Firmicutes,4HPJ0@91061|Bacilli,3FB8C@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1524) - - - - - - - - - - - - DUF1524,DUF262 AFLMLIMI_02077 543734.LCABL_22690 8.78e-172 481.0 29Q4F@1|root,30B35@2|Bacteria,1U7G9@1239|Firmicutes,4IHCF@91061|Bacilli,3F9KY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02078 543734.LCABL_22680 2.81e-279 766.0 COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,4HD25@91061|Bacilli 91061|Bacilli F Permease for cytosine/purines, uracil, thiamine, allantoin - - - ko:K10974 - - - - ko00000,ko02000 2.A.39.1 - - Transp_cyt_pur AFLMLIMI_02079 543734.LCABL_22670 2.93e-260 713.0 COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,4HC1C@91061|Bacilli,3F5F2@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF917) - - - ko:K09703 - - - - ko00000 - - - DUF917 AFLMLIMI_02080 543734.LCABL_22660 0.0 985.0 COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,3F4TR@33958|Lactobacillaceae 91061|Bacilli EQ Hydantoinase/oxoprolinase N-terminal region hyuA - - - - - - - - - - - Hydant_A_N,Hydantoinase_A AFLMLIMI_02081 543734.LCABL_22650 6.84e-186 517.0 COG0524@1|root,COG0524@2|Bacteria,1TSST@1239|Firmicutes,4HGU3@91061|Bacilli,3F7U3@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase frlD1 - 2.7.1.218 ko:K10710 - - R08124 RC00002,RC00017 ko00000,ko01000 - - - PfkB AFLMLIMI_02082 568703.LGG_02085 9.27e-77 236.0 29Q1U@1|root,30B0E@2|Bacteria,1U7CC@1239|Firmicutes,4IH7Q@91061|Bacilli,3F9CG@33958|Lactobacillaceae 91061|Bacilli S WxL domain surface cell wall-binding - - - - - - - - - - - - WxL AFLMLIMI_02083 568703.LGG_02083 4.16e-101 297.0 2AGPG@1|root,316X2@2|Bacteria,1U7BQ@1239|Firmicutes,4IH6V@91061|Bacilli,3F9AE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02084 543734.LCABL_22620 0.0 1700.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli,3F5WR@33958|Lactobacillaceae 91061|Bacilli L Helix-hairpin-helix containing domain - - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,UvrD_C_2 AFLMLIMI_02085 543734.LCABL_22610 7.15e-177 493.0 COG3860@1|root,COG3860@2|Bacteria,1TPHH@1239|Firmicutes,4HCHE@91061|Bacilli,3F56B@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2087) - - - - - - - - - - - - DUF2087,GerE AFLMLIMI_02086 543734.LCABL_22600 2.04e-171 479.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli,3F4KR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD AFLMLIMI_02087 543734.LCABL_22590 0.0 1495.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3F3RU@33958|Lactobacillaceae 91061|Bacilli G alpha-galactosidase galA - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase AFLMLIMI_02088 543734.LCABL_22580 0.0 917.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4H9W2@91061|Bacilli,3F4VG@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane chbC - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_02090 543734.LCABL_22560 6.59e-90 263.0 2DQNY@1|root,337UX@2|Bacteria,1VEZ0@1239|Firmicutes,4HPE2@91061|Bacilli,3F69F@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF3284) - - - - - - - - - - - - DUF3284 AFLMLIMI_02091 543734.LCABL_22550 2.18e-269 736.0 COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,4H9V2@91061|Bacilli,3F4FK@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF871) ybhE - - ko:K09963 - - - - ko00000 - - - DUF871 AFLMLIMI_02092 543734.LCABL_22540 1.09e-68 208.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli 91061|Bacilli G Phosphotransferase system cellobiose-specific component IIA - - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA AFLMLIMI_02093 1423732.BALS01000017_gene1752 2.39e-109 317.0 2AYWY@1|root,30B2F@2|Bacteria,1U7F5@1239|Firmicutes,4IHB5@91061|Bacilli,3F9II@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02094 543734.LCABL_22520 1.7e-190 528.0 COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli,3F4GX@33958|Lactobacillaceae 91061|Bacilli C Cysteine-rich domain lutA - - ko:K18928 - - - - ko00000 - - - CCG AFLMLIMI_02095 543734.LCABL_22510 0.0 995.0 COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,3F4IV@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S dicluster domain lutB - - ko:K18929 - - - - ko00000 - - - DUF3390,Fer4_8,LUD_dom AFLMLIMI_02096 543734.LCABL_22500 3.29e-171 477.0 COG1556@1|root,COG1556@2|Bacteria,1UZAK@1239|Firmicutes,4HH3R@91061|Bacilli,3F4UV@33958|Lactobacillaceae 91061|Bacilli S LUD domain lutC - - ko:K00782 - - - - ko00000 - - - LUD_dom AFLMLIMI_02097 543734.LCABL_22490 4.1e-130 369.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F4EW@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C AFLMLIMI_02098 543734.LCABL_22470 5.45e-295 809.0 COG0477@1|root,COG2814@2|Bacteria,1VSAB@1239|Firmicutes,4HECQ@91061|Bacilli,3FCCN@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 AFLMLIMI_02099 543734.LCABL_22460 0.0 1046.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,3F3JE@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, substratebinding protein oppA - - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AFLMLIMI_02100 543734.LCABL_22450 1.4e-208 578.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli,3F42T@33958|Lactobacillaceae 91061|Bacilli P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 AFLMLIMI_02101 543734.LCABL_22440 3.01e-227 627.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli,3F3W3@33958|Lactobacillaceae 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N AFLMLIMI_02102 543734.LCABL_22430 4.99e-251 689.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AFLMLIMI_02103 543734.LCABL_22420 2.59e-229 632.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AFLMLIMI_02104 543734.LCABL_22410 2.15e-151 425.0 COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F4IS@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm5 - - - - - - - - - - - His_Phos_1 AFLMLIMI_02105 543734.LCABL_22400 6.56e-64 195.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 AFLMLIMI_02106 543734.LCABL_22390 2.1e-49 156.0 2E68Y@1|root,330X0@2|Bacteria,1VFBF@1239|Firmicutes,4HP3V@91061|Bacilli,3F810@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2829) XK27_01315 - - - - - - - - - - - DUF2829 AFLMLIMI_02107 543734.LCABL_22380 4.44e-161 452.0 COG1028@1|root,COG1028@2|Bacteria,1U8IC@1239|Firmicutes,4HC26@91061|Bacilli,3F4X3@33958|Lactobacillaceae 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase fabG - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 AFLMLIMI_02108 543734.LCABL_22370 1.16e-103 301.0 COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli,3F6CG@33958|Lactobacillaceae 91061|Bacilli S QueT transporter ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - QueT AFLMLIMI_02109 543734.LCABL_22360 3.68e-170 475.0 COG2755@1|root,COG2755@2|Bacteria,1UI5G@1239|Firmicutes,4ISEF@91061|Bacilli,3F652@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - AFLMLIMI_02110 1133569.AHYZ01000125_gene2043 2.12e-169 480.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli,3F3R6@33958|Lactobacillaceae 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd AFLMLIMI_02111 1423816.BACQ01000050_gene1851 1.45e-151 433.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli,3F4M5@33958|Lactobacillaceae 91061|Bacilli M biosynthesis protein epsB - - - - - - - - - - - GNVR,Wzz AFLMLIMI_02112 568703.LGG_02052 3.33e-137 392.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,3F4BM@33958|Lactobacillaceae 91061|Bacilli D Capsular exopolysaccharide family ywqD - - - - - - - - - - - AAA_31,ParA AFLMLIMI_02113 568703.LGG_02050 7.29e-59 191.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,3F52G@33958|Lactobacillaceae 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 AFLMLIMI_02114 1423816.BACQ01000050_gene1849 8.5e-155 442.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli,3F52G@33958|Lactobacillaceae 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 AFLMLIMI_02115 220668.lp_1227 1.83e-82 255.0 COG1442@1|root,COG1442@2|Bacteria,1U6EG@1239|Firmicutes,4HG4F@91061|Bacilli,3F539@33958|Lactobacillaceae 91061|Bacilli M Domain of unknown function (DUF4422) cps3J - - - - - - - - - - - DUF4422 AFLMLIMI_02116 1042156.CXIVA_01170 1.09e-104 316.0 COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24GDS@186801|Clostridia,36UTY@31979|Clostridiaceae 186801|Clostridia M Glycosyltransferase like family 2 - - 2.7.8.12 ko:K09809 - - - - ko00000,ko01000 - - - Glycos_transf_2,PS_pyruv_trans AFLMLIMI_02117 411479.BACUNI_00969 5.51e-53 184.0 COG0463@1|root,COG0463@2|Bacteria,4NQ67@976|Bacteroidetes,2G06Z@200643|Bacteroidia,4AV2G@815|Bacteroidaceae 976|Bacteroidetes M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 AFLMLIMI_02119 1122216.AUHW01000006_gene364 1.56e-96 298.0 COG2327@1|root,COG2327@2|Bacteria,1V4VX@1239|Firmicutes,4H3Q6@909932|Negativicutes 909932|Negativicutes S Polysaccharide pyruvyl transferase - - - - - - - - - - - - PS_pyruv_trans AFLMLIMI_02120 1122216.AUHW01000006_gene365 1.37e-131 395.0 COG2244@1|root,COG2244@2|Bacteria,1TR7A@1239|Firmicutes 1239|Firmicutes S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C AFLMLIMI_02121 78345.BMERY_1172 8.98e-54 186.0 COG0778@1|root,COG0778@2|Bacteria,2IE9H@201174|Actinobacteria,4CZI3@85004|Bifidobacteriales 201174|Actinobacteria C Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Nitroreductase AFLMLIMI_02122 1449342.JQMR01000001_gene118 8.4e-65 209.0 COG3774@1|root,COG3774@2|Bacteria,1V3YG@1239|Firmicutes,4HG22@91061|Bacilli,27GFB@186828|Carnobacteriaceae 91061|Bacilli M Glycosyltransferase sugar-binding region containing DXD motif - - - - - - - - - - - - Gly_transf_sug AFLMLIMI_02123 278197.PEPE_0577 2.87e-31 120.0 COG4763@1|root,COG4763@2|Bacteria,1VAZM@1239|Firmicutes 1239|Firmicutes S Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 AFLMLIMI_02124 543734.LCABL_22240 6.49e-66 202.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,3F51J@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase rfbP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K13012,ko:K19428 - - - - ko00000,ko01000,ko01005 - - - Bac_transf,CoA_binding_3 AFLMLIMI_02125 641146.HMPREF9020_01154 1.11e-300 820.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_02126 543734.LCABL_22140 7.05e-195 542.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli,3F3MQ@33958|Lactobacillaceae 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein brpA - - - - - - - - - - - LytR_cpsA_psr AFLMLIMI_02127 543734.LCABL_22130 1.15e-185 515.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli,3F3RT@33958|Lactobacillaceae 91061|Bacilli GM PHP domain protein ywqE - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - AFLMLIMI_02128 543734.LCABL_22120 0.0 1384.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F43D@33958|Lactobacillaceae 91061|Bacilli O associated with various cellular activities clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR AFLMLIMI_02129 543734.LCABL_22110 1.94e-86 254.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F9SP@33958|Lactobacillaceae 91061|Bacilli P ArsC family spx2 - - ko:K16509 - - - - ko00000 - - - ArsC AFLMLIMI_02130 543734.LCABL_22100 0.0 1297.0 COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,4HBAN@91061|Bacilli,3F4MG@33958|Lactobacillaceae 91061|Bacilli G phosphatase activity fbp - 3.1.3.11 ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_2 AFLMLIMI_02131 543734.LCABL_22090 1.29e-186 520.0 COG1284@1|root,COG1284@2|Bacteria,1TWZ5@1239|Firmicutes,4HD8R@91061|Bacilli,3F54A@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - - - - - - - - - - DUF2179,YitT_membrane AFLMLIMI_02132 543734.LCABL_22080 2.89e-135 392.0 COG3764@1|root,COG3764@2|Bacteria,1VXZD@1239|Firmicutes,4HXV4@91061|Bacilli,3F9NX@33958|Lactobacillaceae 91061|Bacilli M Sortase family - - - - - - - - - - - - DUF5011,Sortase AFLMLIMI_02133 543734.LCABL_22070 8.73e-262 715.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli,3F4BD@33958|Lactobacillaceae 91061|Bacilli E Branched-chain amino acid aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 AFLMLIMI_02134 543734.LCABL_22060 0.0 1464.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli,3F4KT@33958|Lactobacillaceae 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 AFLMLIMI_02135 543734.LCABL_22050 1.6e-252 695.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli,3F4IA@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase AFLMLIMI_02136 543734.LCABL_22040 1.39e-279 764.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli,3F58E@33958|Lactobacillaceae 91061|Bacilli G Nucleotidyl transferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase AFLMLIMI_02137 543734.LCABL_22030 0.0 985.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli,3F3PP@33958|Lactobacillaceae 91061|Bacilli F Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 AFLMLIMI_02138 543734.LCABL_22020 0.0 1595.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli,3F4Z1@33958|Lactobacillaceae 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase AFLMLIMI_02139 543734.LCABL_22010 0.0 1224.0 COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,4HB67@91061|Bacilli,3F41N@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family malZ - 3.2.1.20,3.2.1.41 ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 - R00028,R00801,R00802,R02111,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - CBM48,GH13,GH31 - Alpha-amylase,Alpha-amylase_N AFLMLIMI_02140 543734.LCABL_22000 3.12e-222 612.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HHVC@91061|Bacilli,3F3QR@33958|Lactobacillaceae 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE AFLMLIMI_02141 543734.LCABL_21990 5.83e-73 219.0 COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes,4HP5T@91061|Bacilli,3F8JS@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 AFLMLIMI_02142 543734.LCABL_21980 1.32e-221 611.0 COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer AFLMLIMI_02143 543734.LCABL_21970 1.55e-312 850.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,3F48J@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b AFLMLIMI_02144 543734.LCABL_21960 2.08e-187 532.0 COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,4HDAX@91061|Bacilli,3F5PQ@33958|Lactobacillaceae 91061|Bacilli M NlpC/P60 family spl - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60 AFLMLIMI_02145 543734.LCABL_21950 9.94e-90 263.0 COG0454@1|root,COG0456@2|Bacteria,1UHQS@1239|Firmicutes,4IT2E@91061|Bacilli,3FBVW@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 AFLMLIMI_02146 543734.LCABL_21940 7.28e-144 405.0 COG0194@1|root,COG0194@2|Bacteria,1V8PW@1239|Firmicutes,4HJCB@91061|Bacilli,3F6N3@33958|Lactobacillaceae 91061|Bacilli F Guanylate kinase gmk2 - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin AFLMLIMI_02147 543734.LCABL_21930 9.35e-15 66.6 29QNJ@1|root,30BN7@2|Bacteria,1U8CS@1239|Firmicutes,4IIAR@91061|Bacilli,3FAUD@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02148 543734.LCABL_21920 3.91e-109 313.0 COG0735@1|root,COG0735@2|Bacteria,1V6RI@1239|Firmicutes,4HIGM@91061|Bacilli,3F6W3@33958|Lactobacillaceae 91061|Bacilli P Belongs to the Fur family zur - - ko:K02076,ko:K03711 - - - - ko00000,ko03000 - - - FUR AFLMLIMI_02150 543734.LCABL_21900 3e-225 622.0 2C6F0@1|root,32RH8@2|Bacteria,1V7ET@1239|Firmicutes,4HJDI@91061|Bacilli,3F4UC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02151 543734.LCABL_21890 6.35e-174 485.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AFLMLIMI_02152 543734.LCABL_21880 2.05e-189 526.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,3F4GG@33958|Lactobacillaceae 91061|Bacilli ET ABC transporter substrate-binding protein glnH - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 AFLMLIMI_02153 543734.LCABL_21870 8.31e-141 399.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HFBH@91061|Bacilli,3F3XW@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnM GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AFLMLIMI_02154 543734.LCABL_21860 6.51e-141 399.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,3F3WJ@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 AFLMLIMI_02155 543734.LCABL_21850 2.5e-191 535.0 COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,3F5GY@33958|Lactobacillaceae 91061|Bacilli M RmlD substrate binding domain cps2D - 5.1.3.2,5.1.3.25 ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 M00361,M00362,M00632 R00291,R02984,R10279 RC00289 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS00780 Epimerase,GDP_Man_Dehyd AFLMLIMI_02156 543734.LCABL_20250 3.18e-125 374.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase AFLMLIMI_02157 1158609.I586_01142 7.23e-126 385.0 COG1807@1|root,COG1807@2|Bacteria,1TZ29@1239|Firmicutes,4I895@91061|Bacilli,4B21E@81852|Enterococcaceae 91061|Bacilli M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - PMT_2 AFLMLIMI_02158 1123313.ATUT01000016_gene618 3.77e-12 74.7 COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,3VQ6J@526524|Erysipelotrichia 526524|Erysipelotrichia I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 AFLMLIMI_02159 226185.EF_2794 1.22e-64 225.0 2DQSR@1|root,338EM@2|Bacteria,1VAQX@1239|Firmicutes,4HM5B@91061|Bacilli,4B4C5@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - PMT_2 AFLMLIMI_02160 565655.ECBG_02757 8.61e-72 259.0 COG1376@1|root,COG1376@2|Bacteria,1UM6R@1239|Firmicutes,4ITS2@91061|Bacilli,4AZUX@81852|Enterococcaceae 91061|Bacilli S ErfK ybiS ycfS ynhG family protein - - - - - - - - - - - - SH3_8,YkuD AFLMLIMI_02162 1423732.BALS01000012_gene1488 2.37e-250 697.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB15@91061|Bacilli,3F5WM@33958|Lactobacillaceae 91061|Bacilli M Bacterial sugar transferase cps2E - - - - - - - - - - - Bac_transf,CoA_binding_3 AFLMLIMI_02163 1140002.I570_02161 3.5e-106 316.0 COG1215@1|root,COG1215@2|Bacteria,1V1CB@1239|Firmicutes,4HHH7@91061|Bacilli,4B0ZP@81852|Enterococcaceae 91061|Bacilli M Glycosyl transferase family 2 wcaA - - - - - - - - - - - Glycos_transf_2 AFLMLIMI_02164 565664.EFXG_02140 5.14e-147 421.0 COG3475@1|root,COG3475@2|Bacteria,1TT6A@1239|Firmicutes,4HE2E@91061|Bacilli,4B0MD@81852|Enterococcaceae 91061|Bacilli M LicD family licD3 - - ko:K07271 - - - - ko00000,ko01000 - - - LicD AFLMLIMI_02165 1158604.I591_01353 6.19e-132 378.0 COG1211@1|root,COG1211@2|Bacteria,1TS1B@1239|Firmicutes,4HHZZ@91061|Bacilli,4AZAT@81852|Enterococcaceae 91061|Bacilli I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD AFLMLIMI_02166 543734.LCABL_12610 7.45e-155 443.0 COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HC1B@91061|Bacilli,3F6WH@33958|Lactobacillaceae 91061|Bacilli GM Male sterility protein - - 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - Epimerase AFLMLIMI_02167 1260356.D920_01305 3.16e-123 363.0 COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,4HCW0@91061|Bacilli,4B1HJ@81852|Enterococcaceae 91061|Bacilli M group 2 family protein - - - - - - - - - - - - Glycos_transf_2 AFLMLIMI_02168 1158607.UAU_04641 2.47e-185 536.0 COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,4HCW6@91061|Bacilli,4B4J4@81852|Enterococcaceae 91061|Bacilli S Psort location CytoplasmicMembrane, score cps2I - - - - - - - - - - - Polysacc_synt AFLMLIMI_02169 1158607.UAU_04640 4.05e-98 302.0 COG0438@1|root,COG0438@2|Bacteria,1TPHK@1239|Firmicutes,4HAXV@91061|Bacilli,4B3BW@81852|Enterococcaceae 91061|Bacilli M Glycosyl transferases group 1 - - - - - - - - - - - - Glycos_transf_1 AFLMLIMI_02170 1158607.UAU_04639 2.61e-74 248.0 COG3307@1|root,COG3307@2|Bacteria,1VANV@1239|Firmicutes,4IPYQ@91061|Bacilli,4B1Y1@81852|Enterococcaceae 91061|Bacilli M O-Antigen ligase - - - - - - - - - - - - Wzy_C AFLMLIMI_02171 565655.ECBG_02869 4.41e-140 433.0 COG3757@1|root,COG3757@2|Bacteria,1VRSE@1239|Firmicutes,4HI01@91061|Bacilli,4B22J@81852|Enterococcaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25 AFLMLIMI_02172 1139219.I569_00452 3.64e-59 224.0 COG0791@1|root,COG0791@2|Bacteria,1UNZW@1239|Firmicutes,4IUVQ@91061|Bacilli,4B60V@81852|Enterococcaceae 91061|Bacilli M NLP P60 protein - - - - - - - - - - - - - AFLMLIMI_02173 1121344.JHZO01000003_gene831 5.29e-34 135.0 COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia,3WRX3@541000|Ruminococcaceae 186801|Clostridia S Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 AFLMLIMI_02174 543734.LCABL_21740 8.56e-111 328.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli,3FC25@33958|Lactobacillaceae 91061|Bacilli G Polysaccharide deacetylase nodB3 - - - - - - - - - - - Polysacc_deac_1 AFLMLIMI_02175 543734.LCABL_21740 6.81e-29 110.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli,3FC25@33958|Lactobacillaceae 91061|Bacilli G Polysaccharide deacetylase nodB3 - - - - - - - - - - - Polysacc_deac_1 AFLMLIMI_02176 641146.HMPREF9020_01154 4.51e-300 818.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_02177 543734.LCABL_21730 4.57e-304 830.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,3F4B2@33958|Lactobacillaceae 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX - - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 AFLMLIMI_02178 543734.LCABL_21700 8.52e-212 585.0 COG1597@1|root,COG1597@2|Bacteria,1V4PN@1239|Firmicutes,4HHJP@91061|Bacilli,3F3Z6@33958|Lactobacillaceae 91061|Bacilli I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat AFLMLIMI_02179 543734.LCABL_21690 0.0 1087.0 COG0531@1|root,COG0531@2|Bacteria,1VTQI@1239|Firmicutes,4HU7Y@91061|Bacilli,3FBET@33958|Lactobacillaceae 91061|Bacilli E Amino Acid - - - - - - - - - - - - AA_permease_2 AFLMLIMI_02180 543734.LCABL_21680 2.68e-174 486.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein cysA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_02181 543734.LCABL_21670 0.0 1113.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4HAZG@91061|Bacilli,3F45H@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX AFLMLIMI_02182 543734.LCABL_21660 4.03e-164 458.0 COG0406@1|root,COG0406@2|Bacteria,1TQWQ@1239|Firmicutes,4HF2N@91061|Bacilli,3F524@33958|Lactobacillaceae 91061|Bacilli G Phosphoglycerate mutase family gpm2 - - - - - - - - - - - His_Phos_1 AFLMLIMI_02183 543734.LCABL_21650 2e-240 659.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli,3F4VU@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH - 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase AFLMLIMI_02184 543734.LCABL_21640 8.94e-307 838.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli,3F49Y@33958|Lactobacillaceae 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp AFLMLIMI_02185 543734.LCABL_21630 2.51e-103 299.0 2C3KP@1|root,2Z802@2|Bacteria,1TQD1@1239|Firmicutes,4HBGA@91061|Bacilli,3F71P@33958|Lactobacillaceae 91061|Bacilli S Phage tail protein yjhE - - - - - - - - - - - - AFLMLIMI_02186 543734.LCABL_21620 1.62e-229 630.0 COG2267@1|root,COG2267@2|Bacteria,1UEDT@1239|Firmicutes,4HF61@91061|Bacilli,3F47H@33958|Lactobacillaceae 91061|Bacilli E Releases the N-terminal proline from various substrates pepR - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 AFLMLIMI_02187 543734.LCABL_21610 0.0 1150.0 COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,4H9Q5@91061|Bacilli,3F4AZ@33958|Lactobacillaceae 91061|Bacilli P TrkA C-terminal domain protein yjbQ - - ko:K03455,ko:K03499 - - - - ko00000,ko02000 2.A.37,2.A.38.1,2.A.38.4 - - Na_H_Exchanger,TrkA_C,TrkA_N AFLMLIMI_02188 1423816.BACQ01000047_gene1778 3.05e-29 105.0 2AX78@1|root,31P5Y@2|Bacteria,1U818@1239|Firmicutes,4IHYP@91061|Bacilli,3FAEP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02190 543734.LCABL_21600 0.0 1470.0 COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,4H9Y5@91061|Bacilli,3F486@33958|Lactobacillaceae 91061|Bacilli L DNA helicase helD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2 AFLMLIMI_02191 543734.LCABL_21590 1.44e-109 315.0 COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,4HJ0Z@91061|Bacilli,3F6A3@33958|Lactobacillaceae 91061|Bacilli I Thioesterase superfamily ykhA - 3.1.2.20 ko:K01073 - - - - ko00000,ko01000 - - - 4HBT AFLMLIMI_02192 543734.LCABL_21580 0.0 954.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli,3F3M4@33958|Lactobacillaceae 91061|Bacilli E Dipeptidase pepDA - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 AFLMLIMI_02193 543734.LCABL_21570 3.38e-56 175.0 2AHIU@1|root,317WG@2|Bacteria,1U84D@1239|Firmicutes,4II1U@91061|Bacilli,3FAIH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02195 543734.LCABL_21550 2.3e-228 628.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli,3F42Q@33958|Lactobacillaceae 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK AFLMLIMI_02196 543734.LCABL_21540 0.0 1044.0 COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli,3F3NV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase AFLMLIMI_02198 519441.Smon_1417 5.74e-108 328.0 arCOG14100@1|root,2Z924@2|Bacteria,37AU0@32066|Fusobacteria 32066|Fusobacteria S SIR2-like domain - - - - - - - - - - - - SIR2_2 AFLMLIMI_02199 1423807.BACO01000056_gene1641 2.69e-240 675.0 COG0433@1|root,COG0433@2|Bacteria,1TPQN@1239|Firmicutes,4HC61@91061|Bacilli 91061|Bacilli S cog cog0433 - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 AFLMLIMI_02202 1449343.JQLQ01000002_gene120 1.79e-79 258.0 COG2865@1|root,COG2865@2|Bacteria,1UYYR@1239|Firmicutes,4HHVE@91061|Bacilli,27HKY@186828|Carnobacteriaceae 91061|Bacilli K Putative DNA-binding domain - - - - - - - - - - - - AlbA_2 AFLMLIMI_02206 1133569.AHYZ01000154_gene2213 3.66e-37 130.0 COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,4HGQX@91061|Bacilli,3FBC6@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin - - - - - - - - - - - - AbiEi_4 AFLMLIMI_02207 1133569.AHYZ01000154_gene2213 1.31e-12 64.7 COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,4HGQX@91061|Bacilli,3FBC6@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin - - - - - - - - - - - - AbiEi_4 AFLMLIMI_02208 1133569.AHYZ01000154_gene2214 2.89e-70 219.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli,3F4R3@33958|Lactobacillaceae 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii AFLMLIMI_02209 1133569.AHYZ01000154_gene2214 8.14e-63 200.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli,3F4R3@33958|Lactobacillaceae 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii AFLMLIMI_02210 543734.LCABL_21280 1.32e-121 350.0 2DMBI@1|root,32H42@2|Bacteria,1VFT3@1239|Firmicutes,4HK1A@91061|Bacilli,3F7XU@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF4767) yjdB - - - - - - - - - - - DUF4767 AFLMLIMI_02211 543734.LCABL_21270 6.12e-65 198.0 2DCPK@1|root,2ZEV0@2|Bacteria,1TVRG@1239|Firmicutes,4I3X9@91061|Bacilli,3FA25@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain lciIC - - - - - - - - - - - HTH_3 AFLMLIMI_02213 543734.LCABL_21250 9.11e-163 457.0 COG1349@1|root,COG1349@2|Bacteria,1UYQX@1239|Firmicutes,4HMB5@91061|Bacilli,3F6Z8@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain - - - - - - - - - - - - DeoRC,HTH_DeoR AFLMLIMI_02214 543734.LCABL_21230 5.6e-172 481.0 COG5549@1|root,COG5549@2|Bacteria,1V6X9@1239|Firmicutes,4HK8S@91061|Bacilli,3F6QI@33958|Lactobacillaceae 91061|Bacilli O Zinc-dependent metalloprotease zmp3 - - - - - - - - - - - Peptidase_M10 AFLMLIMI_02215 568703.LGG_01953 0.0 1104.0 COG1388@1|root,COG1388@2|Bacteria,1VQJH@1239|Firmicutes,4HSU2@91061|Bacilli,3F4H3@33958|Lactobacillaceae 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM AFLMLIMI_02216 936140.AEOT01000001_gene2370 1.28e-31 111.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3F85E@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 AFLMLIMI_02217 1423816.BACQ01000047_gene1752 2.03e-76 241.0 2DQV2@1|root,338VR@2|Bacteria,1VG1G@1239|Firmicutes,4HQEQ@91061|Bacilli,3F9IH@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase enzyme family - - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH AFLMLIMI_02218 543734.LCABL_21200 3.24e-89 261.0 2F916@1|root,309SE@2|Bacteria,1U5KS@1239|Firmicutes,4IFBR@91061|Bacilli,3F65Y@33958|Lactobacillaceae 91061|Bacilli S Iron-sulphur cluster biosynthesis - - - - - - - - - - - - Fe-S_biosyn AFLMLIMI_02220 543734.LCABL_21180 0.0 990.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F4HU@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_02221 543734.LCABL_21170 0.0 936.0 COG1132@1|root,COG1132@2|Bacteria,1UVV5@1239|Firmicutes,4I2V1@91061|Bacilli,3F9E9@33958|Lactobacillaceae 91061|Bacilli V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran AFLMLIMI_02222 543734.LCABL_21160 3.73e-49 157.0 28QAQ@1|root,2ZCTB@2|Bacteria,1W6HR@1239|Firmicutes,4I0FP@91061|Bacilli,3F7NS@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02223 543734.LCABL_21150 2.12e-70 212.0 COG0640@1|root,COG0640@2|Bacteria,1V6Z2@1239|Firmicutes,4HKFB@91061|Bacilli,3F7CV@33958|Lactobacillaceae 91061|Bacilli K Transcriptional - - - - - - - - - - - - HTH_5 AFLMLIMI_02224 543734.LCABL_21140 1.4e-163 457.0 COG0693@1|root,COG0693@2|Bacteria,1UG8E@1239|Firmicutes,4HCBM@91061|Bacilli,3F4SD@33958|Lactobacillaceae 91061|Bacilli S DJ-1/PfpI family - - - - - - - - - - - - DJ-1_PfpI AFLMLIMI_02225 543734.LCABL_21130 0.0 1076.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HTMF@91061|Bacilli 91061|Bacilli E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 AFLMLIMI_02226 543734.LCABL_21120 1.2e-214 594.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HU8D@91061|Bacilli 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 AFLMLIMI_02227 543734.LCABL_21110 2.18e-222 614.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli 91061|Bacilli EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N AFLMLIMI_02229 543734.LCABL_21090 1.97e-254 698.0 COG0444@1|root,COG0444@2|Bacteria,1VRIF@1239|Firmicutes,4HV11@91061|Bacilli 91061|Bacilli P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AFLMLIMI_02230 543734.LCABL_21080 4.7e-204 565.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HUP0@91061|Bacilli 91061|Bacilli P Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AFLMLIMI_02231 543734.LCABL_21070 2.13e-130 370.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli,3F6YW@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain ydaF GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008999,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017198,GO:0018193,GO:0018209,GO:0019538,GO:0030920,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1990189 - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 AFLMLIMI_02232 525318.HMPREF0497_0206 3.51e-15 80.5 29NT4@1|root,309R6@2|Bacteria,1U5IX@1239|Firmicutes,4HZ1H@91061|Bacilli,3F624@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02233 543734.LCABL_21050 2.19e-159 447.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HC2V@91061|Bacilli,3FC3Q@33958|Lactobacillaceae 91061|Bacilli V ATPases associated with a variety of cellular activities yhcG - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_02234 543734.LCABL_21040 2.73e-80 238.0 COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,4HPK4@91061|Bacilli,3F6GC@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, GntR family lexA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR AFLMLIMI_02235 543734.LCABL_21030 9.54e-209 576.0 COG4814@1|root,COG4814@2|Bacteria,1VSYU@1239|Firmicutes,4HU15@91061|Bacilli,3F4J2@33958|Lactobacillaceae 91061|Bacilli S Alpha beta hydrolase - - - - - - - - - - - - DUF915 AFLMLIMI_02236 543734.LCABL_21020 4.3e-233 643.0 COG1476@1|root,COG1476@2|Bacteria,1V7TA@1239|Firmicutes,4HWM9@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 AFLMLIMI_02237 543734.LCABL_21010 1.36e-159 449.0 COG0730@1|root,COG0730@2|Bacteria,1V75K@1239|Firmicutes,4HEE8@91061|Bacilli,3F6BU@33958|Lactobacillaceae 91061|Bacilli S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE AFLMLIMI_02238 543734.LCABL_21000 0.0 893.0 COG0477@1|root,COG2814@2|Bacteria,1UYQB@1239|Firmicutes,4HE3Y@91061|Bacilli,3F3NG@33958|Lactobacillaceae 91061|Bacilli EGP Major Facilitator - - - - - - - - - - - - MFS_1 AFLMLIMI_02239 543734.LCABL_20990 1.4e-147 416.0 COG1309@1|root,COG1309@2|Bacteria,1VG1F@1239|Firmicutes,4HPER@91061|Bacilli,3F6KD@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_N AFLMLIMI_02240 748671.LCRIS_00537 0.0 1002.0 COG3559@1|root,COG3559@2|Bacteria,1TPIG@1239|Firmicutes,4H9SK@91061|Bacilli,3F4PV@33958|Lactobacillaceae 91061|Bacilli M Exporter of polyketide antibiotics - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - AFLMLIMI_02241 543734.LCABL_20970 7.87e-214 591.0 COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,4HC34@91061|Bacilli,3F4JT@33958|Lactobacillaceae 91061|Bacilli V ABC transporter ybhF_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 AFLMLIMI_02242 543734.LCABL_20960 7.41e-176 490.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,3F4IY@33958|Lactobacillaceae 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase AFLMLIMI_02243 543734.LCABL_20950 7.62e-110 326.0 COG4858@1|root,COG4858@2|Bacteria,1V9IF@1239|Firmicutes,4HKB8@91061|Bacilli,3F6UB@33958|Lactobacillaceae 91061|Bacilli - - ORF00048 - - - - - - - - - - - DUF1129 AFLMLIMI_02244 543734.LCABL_20940 2.66e-74 222.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HKBS@91061|Bacilli,3F70B@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator PadR-like family padR - - ko:K10947 - - - - ko00000,ko03000 - - - PadR AFLMLIMI_02245 543734.LCABL_20930 3.16e-136 386.0 COG2085@1|root,COG2085@2|Bacteria,1V35D@1239|Firmicutes,4HFSW@91061|Bacilli,3F5EP@33958|Lactobacillaceae 91061|Bacilli S NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored AFLMLIMI_02246 543734.LCABL_20920 3.35e-111 320.0 COG0454@1|root,COG0456@2|Bacteria,1V6S5@1239|Firmicutes,4HJJY@91061|Bacilli,3F6HM@33958|Lactobacillaceae 91061|Bacilli K GNAT family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 AFLMLIMI_02247 543734.LCABL_20910 2.57e-133 377.0 COG1859@1|root,COG1859@2|Bacteria,1V49Y@1239|Firmicutes,4HHHZ@91061|Bacilli,3FBCQ@33958|Lactobacillaceae 91061|Bacilli J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase kptA - - ko:K07559 - - - - ko00000,ko01000,ko03016 - - - PTS_2-RNA AFLMLIMI_02248 543734.LCABL_20900 3.61e-55 172.0 2ENWC@1|root,33GHC@2|Bacteria,1VPIM@1239|Firmicutes,4HRIM@91061|Bacilli,3F826@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02249 543734.LCABL_20890 4.1e-307 839.0 COG2851@1|root,COG2851@2|Bacteria,1TQQH@1239|Firmicutes,4HAGT@91061|Bacilli,3F5EB@33958|Lactobacillaceae 91061|Bacilli C Citrate transporter citM - - ko:K03300 - - - - ko00000 2.A.11 - - CitMHS AFLMLIMI_02250 543734.LCABL_20880 3.17e-71 214.0 2EDVU@1|root,337QZ@2|Bacteria,1W0WF@1239|Firmicutes,4HZEA@91061|Bacilli,3F8EE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02251 543734.LCABL_20870 4.02e-61 191.0 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4HJSW@91061|Bacilli,3F7V3@33958|Lactobacillaceae 91061|Bacilli I Biotin-requiring enzyme oadG - - - - - - - - - - - Biotin_lipoyl AFLMLIMI_02252 543734.LCABL_20860 1.13e-250 690.0 COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,4HEF4@91061|Bacilli,3F61X@33958|Lactobacillaceae 91061|Bacilli C Na+-transporting oxaloacetate decarboxylase beta subunit oadB - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta AFLMLIMI_02253 1423747.BAMJ01000008_gene716 3.26e-07 48.1 29PZT@1|root,30AY8@2|Bacteria,1U79B@1239|Firmicutes,4IH46@91061|Bacilli,3F95A@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02254 543734.LCABL_20840 2.47e-227 627.0 COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,4HC6Q@91061|Bacilli,3F4H7@33958|Lactobacillaceae 91061|Bacilli H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase citC - 6.2.1.22 ko:K01910 ko02020,map02020 - R04449 RC00012,RC00039 ko00000,ko00001,ko01000 - - - Acetyltransf_10,Citrate_ly_lig AFLMLIMI_02255 543734.LCABL_20830 3.41e-65 198.0 COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,4HNXD@91061|Bacilli,3F7FR@33958|Lactobacillaceae 91061|Bacilli C Covalent carrier of the coenzyme of citrate lyase citD - - ko:K01646 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001 - - - ACP AFLMLIMI_02256 543734.LCABL_20820 7.46e-201 557.0 COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,3F47Q@33958|Lactobacillaceae 91061|Bacilli G Belongs to the HpcH HpaI aldolase family citE - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI AFLMLIMI_02257 543734.LCABL_20810 0.0 990.0 COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,4HAE1@91061|Bacilli,3F4EA@33958|Lactobacillaceae 91061|Bacilli H Citrate (pro-3S)-lyase alpha chain citF - 2.8.3.10 ko:K01643 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - CitF AFLMLIMI_02258 543734.LCABL_20800 1.38e-121 347.0 COG3697@1|root,COG3697@2|Bacteria,1VB3E@1239|Firmicutes,4HMZ5@91061|Bacilli,3F74S@33958|Lactobacillaceae 91061|Bacilli HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citX - 2.7.7.61 ko:K05964 ko02020,map02020 - R10706 - ko00000,ko00001,ko01000 - - - CitX AFLMLIMI_02259 543734.LCABL_20790 0.0 923.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,4HBJ1@91061|Bacilli,3F58W@33958|Lactobacillaceae 91061|Bacilli C Conserved carboxylase domain oadA - 4.1.1.3 ko:K01571 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - HMGL-like,PYC_OADA AFLMLIMI_02260 543734.LCABL_20780 4.14e-163 456.0 COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,4HATG@91061|Bacilli,3F532@33958|Lactobacillaceae 91061|Bacilli K FCD citR - - - - - - - - - - - FCD,GntR AFLMLIMI_02261 543734.LCABL_20760 5.7e-199 551.0 COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,4HGCS@91061|Bacilli,3F4SU@33958|Lactobacillaceae 91061|Bacilli H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase citG - 2.4.2.52 ko:K05966 ko02020,map02020 - R09675 RC00049,RC00063 ko00000,ko00001,ko01000 - - - CitG AFLMLIMI_02262 543734.LCABL_20750 7.43e-97 281.0 2EIVY@1|root,33CM8@2|Bacteria,1VKJ5@1239|Firmicutes,4HRQ2@91061|Bacilli,3F7QM@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02263 1423816.BACQ01000046_gene1709 1.61e-41 145.0 2AIC8@1|root,318TE@2|Bacteria,1U7KZ@1239|Firmicutes,4IHI2@91061|Bacilli,3F9W0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02264 543734.LCABL_20730 1.25e-201 557.0 COG0657@1|root,COG0657@2|Bacteria,1VEC5@1239|Firmicutes,4HKY6@91061|Bacilli,3F50A@33958|Lactobacillaceae 91061|Bacilli I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3 AFLMLIMI_02265 543734.LCABL_20720 3.9e-202 560.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3F46Z@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2 AFLMLIMI_02266 543734.LCABL_20710 1.03e-150 423.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,3F6BJ@33958|Lactobacillaceae 91061|Bacilli C Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005575,GO:0005576,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N AFLMLIMI_02267 1423732.BALS01000021_gene323 1.43e-25 94.7 COG0267@1|root,COG0267@2|Bacteria,1VGZK@1239|Firmicutes,4HSMA@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 AFLMLIMI_02268 568703.LGG_01903 8.02e-114 328.0 2BIND@1|root,32CVF@2|Bacteria,1U7HI@1239|Firmicutes,4IHE6@91061|Bacilli,3F9PY@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02269 543734.LCABL_20680 3.21e-244 671.0 COG4072@1|root,COG4072@2|Bacteria 2|Bacteria S Protein of unknown function C-terminal (DUF3324) - - - - - - - - - - - - DUF3324,DUF916 AFLMLIMI_02270 543734.LCABL_20670 1.2e-127 362.0 COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,3F5A6@33958|Lactobacillaceae 91061|Bacilli J Acetyltransferase (GNAT) domain yjcK - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 AFLMLIMI_02271 543734.LCABL_20660 4.81e-127 361.0 29V6R@1|root,30GKF@2|Bacteria,1UG8K@1239|Firmicutes,4IF4K@91061|Bacilli,3F5MB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02272 543734.LCABL_20650 0.0 1098.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli,3FCE6@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AFLMLIMI_02273 543734.LCABL_20640 1.39e-168 471.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli,3FCCX@33958|Lactobacillaceae 91061|Bacilli Q Alpha-acetolactate decarboxylase budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy AFLMLIMI_02275 543734.LCABL_20620 0.0 916.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli,3F4BG@33958|Lactobacillaceae 91061|Bacilli E amino acid lysP - - ko:K03293,ko:K11733 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.2 - - AA_permease AFLMLIMI_02276 543734.LCABL_20610 0.0 1017.0 COG3711@1|root,COG3711@2|Bacteria,1UVBC@1239|Firmicutes,4I2VB@91061|Bacilli,3F5V6@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga AFLMLIMI_02277 543734.LCABL_20600 0.0 1039.0 COG3711@1|root,COG3711@2|Bacteria,1VVKT@1239|Firmicutes,4HWA8@91061|Bacilli,3F5TE@33958|Lactobacillaceae 91061|Bacilli K Mga helix-turn-helix domain - - - - - - - - - - - - Mga AFLMLIMI_02278 543734.LCABL_20590 7.38e-292 798.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,3F3M6@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b AFLMLIMI_02279 568703.LGG_00302 1.45e-46 149.0 2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli,3F8E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02282 568703.LGG_00307 5.19e-90 263.0 2DX7X@1|root,32V2Y@2|Bacteria,1VB4V@1239|Firmicutes,4HKWS@91061|Bacilli,3F76M@33958|Lactobacillaceae 91061|Bacilli S COG NOG38524 non supervised orthologous group - - - - - - - - - - - - - AFLMLIMI_02285 543734.LCABL_20510 3.2e-98 288.0 29PA5@1|root,30A8A@2|Bacteria,1U6BM@1239|Firmicutes,4IG39@91061|Bacilli,3F7J0@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02286 1423732.BALS01000053_gene2773 8.14e-79 238.0 29Q3J@1|root,30B27@2|Bacteria,1U7EP@1239|Firmicutes,4IHAJ@91061|Bacilli,3F9HJ@33958|Lactobacillaceae 91061|Bacilli S MucBP domain - - - - - - - - - - - - MucBP AFLMLIMI_02287 543734.LCABL_20490 2.94e-149 420.0 COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HVUN@91061|Bacilli,3F5K7@33958|Lactobacillaceae 91061|Bacilli S NAD(P)H-binding - - - ko:K07118 - - - - ko00000 - - - NAD_binding_10 AFLMLIMI_02290 1423816.BACQ01000064_gene2513 3.99e-224 624.0 COG0582@1|root,COG0582@2|Bacteria,1TPE1@1239|Firmicutes,4HA65@91061|Bacilli,3F3NJ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family int3 - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase AFLMLIMI_02292 568703.LGG_02238 6.33e-17 77.4 2EUB0@1|root,33MTD@2|Bacteria,1W3MW@1239|Firmicutes,4HZUX@91061|Bacilli,3F7TK@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) - - - - - - - - - - - - DUF1827 AFLMLIMI_02295 543734.LCABL_10820 1.24e-139 399.0 COG0569@1|root,COG0569@2|Bacteria,1UJBH@1239|Firmicutes,4ITNB@91061|Bacilli,3FBX7@33958|Lactobacillaceae 91061|Bacilli P Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 AFLMLIMI_02296 543734.LCABL_10830 6.75e-92 268.0 COG2856@1|root,COG2856@2|Bacteria,1W1K0@1239|Firmicutes,4IGCD@91061|Bacilli,3F81Z@33958|Lactobacillaceae 91061|Bacilli E Zn peptidase - - - - - - - - - - - - Peptidase_M48,Peptidase_M78 AFLMLIMI_02297 543734.LCABL_10840 9.08e-71 213.0 COG1396@1|root,COG1396@2|Bacteria,1VEP9@1239|Firmicutes,4HPCR@91061|Bacilli,3F871@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_26,HTH_3 AFLMLIMI_02301 543734.LCABL_05580 5.19e-169 473.0 COG3646@1|root,COG3646@2|Bacteria,1VEBK@1239|Firmicutes,4IR34@91061|Bacilli,3FBM1@33958|Lactobacillaceae 91061|Bacilli S ORF6N domain - - - - - - - - - - - - ORF6C,ORF6N AFLMLIMI_02303 1423732.BALS01000058_gene2819 1.76e-116 334.0 2E3D0@1|root,32YC9@2|Bacteria,1VH17@1239|Firmicutes,4HQ0Y@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02304 1423816.BACQ01000064_gene2520 4.61e-57 176.0 2AESZ@1|root,314PW@2|Bacteria,1VQHP@1239|Firmicutes,4HZNT@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1883) - - - - - - - - - - - - DUF1883 AFLMLIMI_02305 1035184.HMPREF1042_0280 1.21e-06 50.8 COG4707@1|root,COG4707@2|Bacteria,1VDBG@1239|Firmicutes,4HKZG@91061|Bacilli,42EB8@671232|Streptococcus anginosus group 91061|Bacilli S Domain of unknown function (DUF771) - - - - - - - - - - - - DUF771 AFLMLIMI_02309 1423816.BACQ01000064_gene2523 2.79e-129 372.0 COG3935@1|root,COG3935@2|Bacteria,1VHK1@1239|Firmicutes,4HQY7@91061|Bacilli,3FCF5@33958|Lactobacillaceae 91061|Bacilli L Helix-turn-helix domain - - - - - - - - - - - - DnaB_2,HTH_36 AFLMLIMI_02310 543734.LCABL_05660 2.82e-196 544.0 COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,4HH4U@91061|Bacilli,3F6BK@33958|Lactobacillaceae 91061|Bacilli L IstB-like ATP binding protein pi346 - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 AFLMLIMI_02316 146269.A8YQN1_9CAUD 1.49e-92 271.0 4QAU8@10239|Viruses,4QWW2@35237|dsDNA viruses no RNA stage,4QRF5@28883|Caudovirales,4QN1H@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - AFLMLIMI_02318 1423732.BALS01000006_gene651 8.98e-16 70.9 29QHS@1|root,30BH8@2|Bacteria,1U84C@1239|Firmicutes,4II1T@91061|Bacilli,3FAIG@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02320 146269.A8YQN3_9CAUD 6.38e-300 817.0 4QCT4@10239|Viruses,4QWIG@35237|dsDNA viruses no RNA stage,4QQW8@28883|Caudovirales,4QN4I@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - AFLMLIMI_02321 543734.LCABL_05780 1.01e-67 205.0 2BWYP@1|root,30AJY@2|Bacteria,1U6SS@1239|Firmicutes,4IGKB@91061|Bacilli,3F8F9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02324 941770.GL622178_gene362 1.79e-44 151.0 COG1403@1|root,COG1403@2|Bacteria,1VQIP@1239|Firmicutes,4HM74@91061|Bacilli,3F6KP@33958|Lactobacillaceae 91061|Bacilli L HNH nucleases - - - - - - - - - - - - AAA_33,HNH AFLMLIMI_02325 1423755.BAML01000004_gene388 1.44e-49 163.0 COG3747@1|root,COG3747@2|Bacteria,1VW7W@1239|Firmicutes,4HR5B@91061|Bacilli,3F43B@33958|Lactobacillaceae 91061|Bacilli L Phage terminase, small subunit - - - - - - - - - - - - Terminase_4 AFLMLIMI_02326 278197.PEPE_1005 0.0 909.0 COG4626@1|root,COG4626@2|Bacteria,1TR5W@1239|Firmicutes,4HEDC@91061|Bacilli,3FB4K@33958|Lactobacillaceae 91061|Bacilli S Phage Terminase - - - - - - - - - - - - Terminase_1 AFLMLIMI_02328 1605.Lani381_0384 1.52e-123 369.0 COG4695@1|root,COG4695@2|Bacteria,1UY1R@1239|Firmicutes,4HDQZ@91061|Bacilli,3FB4M@33958|Lactobacillaceae 91061|Bacilli S Phage portal protein - - - - - - - - - - - - Phage_portal AFLMLIMI_02329 797515.HMPREF9103_02438 9.15e-79 243.0 COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,4HBZH@91061|Bacilli,3F5E9@33958|Lactobacillaceae 91061|Bacilli OU Belongs to the peptidase S14 family - - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease AFLMLIMI_02330 1423807.BACO01000084_gene2449 2.27e-139 411.0 COG4653@1|root,COG4653@2|Bacteria,1UACS@1239|Firmicutes,4HEAS@91061|Bacilli,3FB8A@33958|Lactobacillaceae 91061|Bacilli S Phage capsid family - - - - - - - - - - - - Phage_capsid AFLMLIMI_02332 1423732.BALS01000128_gene2492 5.36e-67 204.0 2E799@1|root,331SU@2|Bacteria,1VJW9@1239|Firmicutes,4HPEE@91061|Bacilli,3F8PZ@33958|Lactobacillaceae 91061|Bacilli S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join AFLMLIMI_02333 146269.A8YQJ5_9CAUD 8.7e-86 253.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - AFLMLIMI_02334 146269.A8YQJ6_9CAUD 7.58e-77 229.0 4QAVH@10239|Viruses,4QX2F@35237|dsDNA viruses no RNA stage,4QR7A@28883|Caudovirales,4QM2J@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF806) - - - - - - - - - - - - - AFLMLIMI_02335 1122147.AUEH01000019_gene953 1.44e-130 372.0 2AZAN@1|root,31RHY@2|Bacteria,1V7ZH@1239|Firmicutes,4HJVX@91061|Bacilli,3F4AS@33958|Lactobacillaceae 91061|Bacilli S Phage tail tube protein - - - - - - - - - - - - Phage_TTP_1 AFLMLIMI_02336 1423732.BALS01000063_gene2228 2.41e-29 109.0 2ETGD@1|root,33M08@2|Bacteria,1VKVE@1239|Firmicutes,4HSUY@91061|Bacilli,3F708@33958|Lactobacillaceae 91061|Bacilli S Phage tail assembly chaperone proteins, TAC - - - - - - - - - - - - Phage_TAC_3 AFLMLIMI_02337 1122147.AUEH01000011_gene2115 4.01e-260 789.0 COG1196@1|root,COG5283@1|root,COG1196@2|Bacteria,COG5283@2|Bacteria,1UZN8@1239|Firmicutes,4HGQG@91061|Bacilli,3F3T2@33958|Lactobacillaceae 91061|Bacilli L Phage tail tape measure protein TP901 - - - - - - - - - - - - NLPC_P60,PhageMin_Tail,SLT AFLMLIMI_02338 568703.LGG_01525 1.22e-158 487.0 COG3953@1|root,COG5283@1|root,COG3953@2|Bacteria,COG5283@2|Bacteria,1UZN8@1239|Firmicutes,4HGQG@91061|Bacilli,3F3T2@33958|Lactobacillaceae 91061|Bacilli L Phage tail tape measure protein TP901 - - - - - - - - - - - - NLPC_P60,PhageMin_Tail,SLT AFLMLIMI_02339 146269.Q7Y4B1_9CAUD 1.22e-193 567.0 4QBF8@10239|Viruses,4QUS7@35237|dsDNA viruses no RNA stage,4QPI9@28883|Caudovirales,4QKN2@10699|Siphoviridae 10699|Siphoviridae S Phage tail protein - - - - - - - - - - - - - AFLMLIMI_02340 146269.A8YQK1_9CAUD 0.0 1286.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - AFLMLIMI_02341 146269.A8YQK2_9CAUD 3.25e-43 143.0 4QH1E@10239|Viruses,4QZAD@35237|dsDNA viruses no RNA stage,4QSYR@28883|Caudovirales 28883|Caudovirales - - - - - - - - - - - - - - - AFLMLIMI_02343 568703.LGG_01141 2.96e-56 176.0 2C26M@1|root,30A6X@2|Bacteria,1U69U@1239|Firmicutes,4IG11@91061|Bacilli,3F7E8@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02344 1423732.BALS01000111_gene29 4.67e-83 247.0 2FDCN@1|root,345EF@2|Bacteria,1W0SS@1239|Firmicutes,4HXYE@91061|Bacilli,3F8B6@33958|Lactobacillaceae 91061|Bacilli S Bacteriophage holin of superfamily 6 (Holin_LLH) - - - - - - - - - - - - Phage_holin_6_1 AFLMLIMI_02346 1423732.BALS01000140_gene526 2.58e-275 759.0 COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V16P@1239|Firmicutes,4HF99@91061|Bacilli,3FC13@33958|Lactobacillaceae 91061|Bacilli M Glycosyl hydrolases family 25 - - - - - - - - - - - - Glyco_hydro_25,LysM,SH3_5 AFLMLIMI_02350 543734.LCABL_20460 4.77e-167 468.0 COG2755@1|root,COG2755@2|Bacteria,1UI5G@1239|Firmicutes,4ISEF@91061|Bacilli,3F6R2@33958|Lactobacillaceae 91061|Bacilli E lipolytic protein G-D-S-L family - - - - - - - - - - - - - AFLMLIMI_02351 1423816.BACQ01000001_gene6 4.14e-91 269.0 COG1918@1|root,COG1918@2|Bacteria,1VFH1@1239|Firmicutes,4HMT6@91061|Bacilli,3FBMK@33958|Lactobacillaceae 91061|Bacilli P FeoA - - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA AFLMLIMI_02352 543734.LCABL_20430 0.0 1357.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli,3F553@33958|Lactobacillaceae 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate AFLMLIMI_02353 568703.LGG_01877 6.28e-25 93.6 2BP56@1|root,32HW1@2|Bacteria,1U802@1239|Firmicutes,4IHXF@91061|Bacilli,3FADE@33958|Lactobacillaceae 91061|Bacilli S Virus attachment protein p12 family - - - - - - - - - - - - P12 AFLMLIMI_02354 543734.LCABL_20410 0.0 1099.0 COG1274@1|root,COG1274@2|Bacteria,1UIM9@1239|Firmicutes,4HED4@91061|Bacilli,3FBXE@33958|Lactobacillaceae 91061|Bacilli C Phosphoenolpyruvate carboxykinase pckA - 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP AFLMLIMI_02355 543734.LCABL_20400 8.15e-77 228.0 29MVS@1|root,308TH@2|Bacteria,1U8JK@1239|Firmicutes,4IIHJ@91061|Bacilli,3FB21@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02356 543734.LCABL_20390 3.21e-293 798.0 COG3669@1|root,COG3669@2|Bacteria,1UYIM@1239|Firmicutes,4HJ46@91061|Bacilli,3F5S7@33958|Lactobacillaceae 91061|Bacilli G Alpha-L-fucosidase - - 3.2.1.51 ko:K01206 ko00511,map00511 - - - ko00000,ko00001,ko01000,ko04147 - GH29 - Alpha_L_fucos AFLMLIMI_02357 543734.LCABL_20380 0.0 916.0 COG2211@1|root,COG2211@2|Bacteria,1TS1S@1239|Firmicutes 1239|Firmicutes G MFS/sugar transport protein - - - - - - - - - - - - MFS_2 AFLMLIMI_02358 543734.LCABL_20370 6.13e-100 289.0 29PS8@1|root,30AQG@2|Bacteria,1U6ZG@1239|Firmicutes,4IGTR@91061|Bacilli,3F8RT@33958|Lactobacillaceae 91061|Bacilli S function, without similarity to other proteins - - - - - - - - - - - - - AFLMLIMI_02359 543734.LCABL_20360 1.71e-87 256.0 29P63@1|root,30A48@2|Bacteria,1U666@1239|Firmicutes,4IFWC@91061|Bacilli,3F75Z@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02360 543734.LCABL_20350 0.0 1450.0 COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBK7@91061|Bacilli,3F44P@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K02003,ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,FtsX,MacB_PCD AFLMLIMI_02361 543734.LCABL_20340 0.0 922.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli,3F4WU@33958|Lactobacillaceae 91061|Bacilli U amino acid peptide transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 AFLMLIMI_02362 543734.LCABL_20330 2.43e-202 559.0 COG1409@1|root,COG1409@2|Bacteria,1VHY9@1239|Firmicutes,4HPAR@91061|Bacilli,3F3SW@33958|Lactobacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos AFLMLIMI_02365 543734.LCABL_20300 0.0 1362.0 COG1506@1|root,COG1506@2|Bacteria,1TR2N@1239|Firmicutes,4H9RR@91061|Bacilli,3F59I@33958|Lactobacillaceae 91061|Bacilli E Prolyl oligopeptidase family yuxL - 3.4.19.1 ko:K01303 - - - - ko00000,ko01000,ko01002 - - - PD40,Peptidase_S9 AFLMLIMI_02366 543734.LCABL_20290 6.51e-177 494.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4H9RV@91061|Bacilli,3F4SE@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer AFLMLIMI_02367 543734.LCABL_20280 7.45e-280 764.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,3F40F@33958|Lactobacillaceae 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046348,GO:0046872,GO:0046914,GO:0046983,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 AFLMLIMI_02368 543734.LCABL_20270 1.62e-161 452.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,3F4D0@33958|Lactobacillaceae 91061|Bacilli K UbiC transcription regulator-associated domain protein yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_02369 543734.LCABL_20260 0.0 951.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli,3F3K7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase AFLMLIMI_02370 543734.LCABL_20250 9.09e-280 765.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase AFLMLIMI_02371 543734.LCABL_20240 2.51e-195 541.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli,3F43Z@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase AFLMLIMI_02373 543734.LCABL_20230 6.59e-276 754.0 COG1680@1|root,COG1680@2|Bacteria,1V0GX@1239|Firmicutes,4HCXH@91061|Bacilli,3F4TH@33958|Lactobacillaceae 91061|Bacilli V Beta-lactamase - - - - - - - - - - - - Beta-lactamase AFLMLIMI_02374 543734.LCABL_20220 0.0 1671.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,3F3KP@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase AFLMLIMI_02375 543734.LCABL_20210 1.17e-95 279.0 2E7AN@1|root,331U3@2|Bacteria,1VFU9@1239|Firmicutes,4HY33@91061|Bacilli,3FBB1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02376 568703.LGG_01853 1.43e-197 552.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli,3F462@33958|Lactobacillaceae 91061|Bacilli S ABC transporter XK27_08835 - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind AFLMLIMI_02377 543734.LCABL_20160 2.83e-188 526.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli,3F40J@33958|Lactobacillaceae 91061|Bacilli U Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 AFLMLIMI_02378 543734.LCABL_20150 2.36e-167 469.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli,3F3NW@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran AFLMLIMI_02379 543734.LCABL_20140 1.65e-111 319.0 COG3091@1|root,COG3091@2|Bacteria,1V6NU@1239|Firmicutes,4HIHY@91061|Bacilli,3F703@33958|Lactobacillaceae 91061|Bacilli S Belongs to the SprT family ydcK - - ko:K03095 - - - - ko00000 - - - SprT-like,Zn_ribbon_SprT AFLMLIMI_02380 543734.LCABL_20130 5.69e-105 303.0 COG0454@1|root,COG0456@2|Bacteria,1VEF8@1239|Firmicutes 1239|Firmicutes K Acetyltransferase GNAT Family - - - - - - - - - - - - Acetyltransf_1 AFLMLIMI_02382 543734.LCABL_20110 4.33e-132 375.0 COG4684@1|root,COG4684@2|Bacteria,1VB4T@1239|Firmicutes,4HMUC@91061|Bacilli,3F497@33958|Lactobacillaceae 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt AFLMLIMI_02383 543734.LCABL_20100 5.16e-270 739.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AFLMLIMI_02384 543734.LCABL_20090 6.18e-199 550.0 COG2017@1|root,COG2017@2|Bacteria 2|Bacteria G converts alpha-aldose to the beta-anomer - - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim AFLMLIMI_02385 543734.LCABL_20080 1.05e-132 376.0 COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,4HM6M@91061|Bacilli,3F8C4@33958|Lactobacillaceae 91061|Bacilli V Restriction endonuclease - - - ko:K07448 - - - - ko00000,ko02048 - - - Mrr_cat AFLMLIMI_02386 543734.LCABL_20070 6.72e-205 566.0 COG1082@1|root,COG1082@2|Bacteria,1VSC9@1239|Firmicutes,4HUQI@91061|Bacilli,3F4RS@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 AFLMLIMI_02387 543734.LCABL_20060 1.46e-65 199.0 2B6X8@1|root,31ZX5@2|Bacteria,1U6HZ@1239|Firmicutes,4IGAA@91061|Bacilli,3F7YC@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02388 543734.LCABL_20050 2.33e-264 726.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,3F3Q5@33958|Lactobacillaceae 91061|Bacilli I Belongs to the thiolase family atoB - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red,Thiolase_C,Thiolase_N AFLMLIMI_02389 543734.LCABL_20040 7.37e-264 728.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli,3F3YY@33958|Lactobacillaceae 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red AFLMLIMI_02390 543734.LCABL_20030 2.6e-279 763.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli,3F425@33958|Lactobacillaceae 91061|Bacilli I Hydroxymethylglutaryl-CoA synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N AFLMLIMI_02391 543734.LCABL_20020 0.0 976.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family poxL - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AFLMLIMI_02392 543734.LCABL_20020 4.98e-43 153.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HBUS@91061|Bacilli,3F3R9@33958|Lactobacillaceae 91061|Bacilli EH Belongs to the TPP enzyme family poxL - 1.2.3.3 ko:K00158 ko00620,ko01100,map00620,map01100 - R00207 RC02745 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N AFLMLIMI_02393 543734.LCABL_20010 6.27e-67 203.0 COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4HKG9@91061|Bacilli,3F7XZ@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit ptcB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB AFLMLIMI_02394 543734.LCABL_20000 7.89e-66 200.0 COG1447@1|root,COG1447@2|Bacteria,1VEGE@1239|Firmicutes,4HM37@91061|Bacilli,3FA2W@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA AFLMLIMI_02395 543734.LCABL_19990 2.36e-111 320.0 2E5MG@1|root,330CD@2|Bacteria,1VE22@1239|Firmicutes,4IRFH@91061|Bacilli,3FBP1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02396 543734.LCABL_19980 8.54e-28 110.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli,3FC70@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_02397 543734.LCABL_19980 9.23e-268 736.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli,3FC70@33958|Lactobacillaceae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC AFLMLIMI_02398 543734.LCABL_19970 0.0 1000.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,3F3PQ@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AFLMLIMI_02399 543734.LCABL_19960 2.13e-172 481.0 COG2188@1|root,COG2188@2|Bacteria,1V4DC@1239|Firmicutes,4HIDU@91061|Bacilli,3F6TC@33958|Lactobacillaceae 91061|Bacilli K UTRA - - - ko:K03489 - - - - ko00000,ko03000 - - - GntR,UTRA AFLMLIMI_02400 543734.LCABL_19950 1.68e-103 300.0 COG3613@1|root,COG3613@2|Bacteria,1V3SN@1239|Firmicutes,4HH4T@91061|Bacilli,3F6KR@33958|Lactobacillaceae 91061|Bacilli F Nucleoside 2-deoxyribosyltransferase - - - - - - - - - - - - Nuc_deoxyrib_tr AFLMLIMI_02401 543734.LCABL_19940 0.0 886.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,3F4GQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr AFLMLIMI_02402 543734.LCABL_19920 6.46e-83 245.0 29Q60@1|root,30B4X@2|Bacteria,1U7J8@1239|Firmicutes,4IHG5@91061|Bacilli,3F9T1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02403 543734.LCABL_19910 0.0 1008.0 COG3711@1|root,COG3711@2|Bacteria 2|Bacteria K transcriptional antiterminator frvR GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K02538,ko:K03483,ko:K09685,ko:K18531 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 AFLMLIMI_02404 543734.LCABL_19900 1.96e-182 508.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HJ7R@91061|Bacilli,3F4BY@33958|Lactobacillaceae 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX AFLMLIMI_02405 543734.LCABL_19890 1.1e-134 380.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli,3F48S@33958|Lactobacillaceae 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 AFLMLIMI_02406 543734.LCABL_19880 1.11e-122 349.0 29NVN@1|root,30AEE@2|Bacteria,1U6J7@1239|Firmicutes,4IGBR@91061|Bacilli,3F80T@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02407 543734.LCABL_19870 4.61e-97 282.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli,3F6HQ@33958|Lactobacillaceae 91061|Bacilli S Acetyltransferase (GNAT) domain yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 AFLMLIMI_02408 543734.LCABL_19860 4.17e-262 720.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,3F418@33958|Lactobacillaceae 91061|Bacilli S AI-2E family transporter yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport AFLMLIMI_02409 543734.LCABL_19850 2.05e-311 850.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,3F3KG@33958|Lactobacillaceae 91061|Bacilli S Transporter associated domain hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 AFLMLIMI_02410 543734.LCABL_19840 0.0 1051.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli,3F489@33958|Lactobacillaceae 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C AFLMLIMI_02412 543734.LCABL_19820 3.36e-61 188.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli,3F70G@33958|Lactobacillaceae 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 AFLMLIMI_02413 543734.LCABL_19810 0.0 1240.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli,3F3K9@33958|Lactobacillaceae 91061|Bacilli O Belongs to the ClpA ClpB family clpE - - ko:K03697,ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR AFLMLIMI_02414 1423816.BACQ01000003_gene57 9.5e-39 129.0 2EI19@1|root,33BSS@2|Bacteria,1VKXC@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - AFLMLIMI_02415 1423732.BALS01000007_gene584 1.02e-51 163.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli,3F6XQ@33958|Lactobacillaceae 91061|Bacilli G phosphocarrier protein HPR ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr AFLMLIMI_02416 543734.LCABL_19780 0.0 1109.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3F3MS@33958|Lactobacillaceae 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C AFLMLIMI_02417 543734.LCABL_19770 0.0 893.0 COG0477@1|root,COG2814@2|Bacteria,1TREV@1239|Firmicutes,4HAN1@91061|Bacilli,3F3ZS@33958|Lactobacillaceae 91061|Bacilli EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family iolT GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - ko:K06609 - - - - ko00000,ko02000 2.A.1.1.26 - - Sugar_tr AFLMLIMI_02418 543734.LCABL_19760 3.87e-135 383.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli,3F738@33958|Lactobacillaceae 91061|Bacilli S Thiamine transporter protein (Thia_YuaJ) thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ AFLMLIMI_02419 543734.LCABL_19750 2.66e-102 297.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,3F6P0@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC AFLMLIMI_02420 543734.LCABL_19740 6.06e-274 748.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,3F3YV@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp AFLMLIMI_02421 543734.LCABL_19730 3.83e-171 478.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli,3F44Z@33958|Lactobacillaceae 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt AFLMLIMI_02422 543734.LCABL_19720 8.48e-55 171.0 COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli,3F81F@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU06460 PurS AFLMLIMI_02423 543734.LCABL_19710 1.39e-164 460.0 COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,3F48D@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 AFLMLIMI_02424 543734.LCABL_19700 0.0 1438.0 COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,3F4IQ@33958|Lactobacillaceae 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C AFLMLIMI_02425 543734.LCABL_19690 0.0 956.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli,3F3U7@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran AFLMLIMI_02426 543734.LCABL_19680 5.92e-236 649.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,3F4RT@33958|Lactobacillaceae 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C AFLMLIMI_02427 543734.LCABL_19670 5.57e-129 367.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,3F3UN@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N AFLMLIMI_02428 543734.LCABL_19660 0.0 991.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,3F4FD@33958|Lactobacillaceae 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS AFLMLIMI_02429 543734.LCABL_19650 5.25e-298 813.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,3F4Z8@33958|Lactobacillaceae 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N AFLMLIMI_02430 543734.LCABL_19640 7.93e-99 287.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli,3F7D0@33958|Lactobacillaceae 91061|Bacilli K Copper transport repressor CopY TcrY copR - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R AFLMLIMI_02431 543734.LCABL_19630 0.0 1335.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,3F4IX@33958|Lactobacillaceae 91061|Bacilli P P-type ATPase copB - 3.6.3.3,3.6.3.4,3.6.3.5 ko:K01533,ko:K01534 - - R00086 RC00002 ko00000,ko01000 3.A.3.5,3.A.3.6 - - E1-E2_ATPase,Hydrolase AFLMLIMI_02432 543734.LCABL_19620 1.54e-141 399.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli,3F46H@33958|Lactobacillaceae 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM AFLMLIMI_02433 543734.LCABL_19610 1.58e-262 719.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HCB6@91061|Bacilli,3FBXD@33958|Lactobacillaceae 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - ko:K19168 - - - - ko00000,ko02048 - - - HATPase_c AFLMLIMI_02434 543734.LCABL_19600 1.83e-158 444.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli,3F5NZ@33958|Lactobacillaceae 91061|Bacilli K response regulator rrp1 - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C AFLMLIMI_02435 543734.LCABL_19590 1.14e-177 495.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F5FY@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_02436 543734.LCABL_19580 0.0 1229.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,3F5VK@33958|Lactobacillaceae 91061|Bacilli V ABC transporter (permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX AFLMLIMI_02437 543734.LCABL_19570 7.88e-121 344.0 COG2329@1|root,COG2329@2|Bacteria 2|Bacteria S heme oxygenase (decyclizing) activity traP GO:0005575,GO:0016020 1.14.99.57,6.2.1.3 ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - ABM AFLMLIMI_02438 543734.LCABL_19560 3.28e-176 491.0 COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,3F4U0@33958|Lactobacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily yhfI GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - - - - - - - - - - Lactamase_B,Lactamase_B_2 AFLMLIMI_02439 543734.LCABL_19550 1.13e-89 263.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli,3F6HJ@33958|Lactobacillaceae 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC AFLMLIMI_02440 543734.LCABL_19540 1.44e-157 442.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli,3F5G4@33958|Lactobacillaceae 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA AFLMLIMI_02441 543734.LCABL_19530 0.0 1161.0 COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UG1C@1239|Firmicutes,4HCPQ@91061|Bacilli,3F3SZ@33958|Lactobacillaceae 91061|Bacilli C phosphodiesterase glpQ4 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD,GPDPase_memb AFLMLIMI_02442 543734.LCABL_19520 2.12e-226 623.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBFE@91061|Bacilli,3FC4P@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the conversion of dihydroorotate to orotate pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh AFLMLIMI_02443 543734.LCABL_19510 1.16e-31 110.0 29QNK@1|root,30BN8@2|Bacteria,1U8CT@1239|Firmicutes,4IIAS@91061|Bacilli,3FAUE@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02444 543734.LCABL_19500 1.97e-88 259.0 2A8KV@1|root,30XP9@2|Bacteria,1U6R7@1239|Firmicutes,4IGII@91061|Bacilli,3F8CJ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02446 543734.LCABL_19480 0.0 1107.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,3F4DE@33958|Lactobacillaceae 91061|Bacilli J Arginyl-tRNA synthetase argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d AFLMLIMI_02447 543734.LCABL_19470 3.31e-98 286.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HN5H@91061|Bacilli,3FBR5@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR1 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C AFLMLIMI_02448 543734.LCABL_19460 1.3e-198 550.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli,3F50K@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 AFLMLIMI_02449 543734.LCABL_19450 0.0 1351.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F49Q@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase AFLMLIMI_02450 543734.LCABL_19440 1.03e-72 218.0 COG3679@1|root,COG3679@2|Bacteria,1V62T@1239|Firmicutes,4IRH3@91061|Bacilli,3FBP8@33958|Lactobacillaceae 91061|Bacilli S Control of competence regulator ComK, YlbF/YmcA - - - - - - - - - - - - Com_YlbF AFLMLIMI_02451 543734.LCABL_19430 8.42e-232 638.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli,3F4SF@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon AFLMLIMI_02452 543734.LCABL_19420 6.14e-204 565.0 COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4HC85@91061|Bacilli,3F45W@33958|Lactobacillaceae 91061|Bacilli M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins prsA GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_2,Rotamase_3 AFLMLIMI_02453 543734.LCABL_19410 5.77e-81 240.0 COG4980@1|root,COG4980@2|Bacteria,1VM8M@1239|Firmicutes,4HR25@91061|Bacilli,3F7TT@33958|Lactobacillaceae 91061|Bacilli S YtxH-like protein - - - - - - - - - - - - YtxH AFLMLIMI_02454 543734.LCABL_19400 2.56e-98 285.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli,3F6K5@33958|Lactobacillaceae 91061|Bacilli FG histidine triad hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT AFLMLIMI_02455 543734.LCABL_19390 2.4e-172 481.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli,3F444@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran AFLMLIMI_02456 543734.LCABL_19380 4.12e-275 754.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli,3F4HH@33958|Lactobacillaceae 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB AFLMLIMI_02457 543734.LCABL_19370 1.51e-187 520.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,3F4GU@33958|Lactobacillaceae 91061|Bacilli M Choline/ethanolamine kinase ytmP - - - - - - - - - - - APH AFLMLIMI_02458 543734.LCABL_19350 1.92e-155 436.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli,3F3QM@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 AFLMLIMI_02459 1175629.AJTG01000028_gene188 5.99e-06 49.3 COG5584@1|root,COG5584@2|Bacteria,1TX5V@1239|Firmicutes,4I627@91061|Bacilli,27E5S@186827|Aerococcaceae 91061|Bacilli S Small secreted protein - - - - - - - - - - - - - AFLMLIMI_02460 543734.LCABL_19330 5.32e-73 218.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli,3F72K@33958|Lactobacillaceae 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin AFLMLIMI_02461 543734.LCABL_19320 3.17e-149 420.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli,3FBJ0@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind AFLMLIMI_02462 543734.LCABL_19310 0.0 1421.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4HA1S@91061|Bacilli,3F441@33958|Lactobacillaceae 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family sftA - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_SpoIIIE,Ftsk_gamma AFLMLIMI_02463 543734.LCABL_19300 9.68e-147 422.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M AFLMLIMI_02464 543734.LCABL_19300 8.44e-152 435.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli,3F49J@33958|Lactobacillaceae 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M AFLMLIMI_02465 543734.LCABL_19290 8.52e-154 433.0 COG0670@1|root,COG0670@2|Bacteria,1V9CJ@1239|Firmicutes,4HM3D@91061|Bacilli,3FBMQ@33958|Lactobacillaceae 91061|Bacilli S Inhibitor of apoptosis-promoting Bax1 ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I AFLMLIMI_02466 543734.LCABL_19280 0.0 1716.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,3F3ZA@33958|Lactobacillaceae 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A AFLMLIMI_02467 543734.LCABL_19270 1.85e-205 568.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS AFLMLIMI_02468 543734.LCABL_19260 1.91e-130 371.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,3F6WF@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE AFLMLIMI_02469 543734.LCABL_19250 2.06e-103 299.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli,3F65S@33958|Lactobacillaceae 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone AFLMLIMI_02470 543734.LCABL_19240 1.04e-303 830.0 COG3611@1|root,COG3611@2|Bacteria,1TSBB@1239|Firmicutes,4H9RI@91061|Bacilli,3F5D7@33958|Lactobacillaceae 91061|Bacilli L replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 AFLMLIMI_02471 568703.LGG_01756 1.02e-180 508.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli,3F4JK@33958|Lactobacillaceae 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 AFLMLIMI_02473 543734.LCABL_19210 0.0 1327.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli,3F3TC@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD AFLMLIMI_02474 543734.LCABL_19200 1.17e-130 371.0 COG0406@1|root,COG0406@2|Bacteria,1V8SE@1239|Firmicutes,4HJCU@91061|Bacilli,3F86H@33958|Lactobacillaceae 91061|Bacilli G Histidine phosphatase superfamily (branch 1) yrgI - 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 AFLMLIMI_02475 568703.LGG_01753 5.3e-70 214.0 29Q5P@1|root,30B4K@2|Bacteria,1U7IT@1239|Firmicutes,4IHFJ@91061|Bacilli,3F9S3@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02476 543734.LCABL_19180 3.99e-166 464.0 2DMFR@1|root,32R83@2|Bacteria,1VJJ0@1239|Firmicutes,4HQP8@91061|Bacilli 91061|Bacilli S SseB protein N-terminal domain - - - - - - - - - - - - SseB,SseB_C AFLMLIMI_02477 543734.LCABL_19170 7.46e-101 293.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,3F4MS@33958|Lactobacillaceae 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N AFLMLIMI_02478 543734.LCABL_19160 1.13e-36 124.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli,3F7CQ@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p AFLMLIMI_02479 543734.LCABL_19150 1.02e-74 224.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,3F6HZ@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 AFLMLIMI_02480 543734.LCABL_19140 8.27e-130 369.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HE2X@91061|Bacilli,3F5U4@33958|Lactobacillaceae 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox AFLMLIMI_02481 543734.LCABL_19130 7.15e-230 633.0 COG0604@1|root,COG0604@2|Bacteria,1V7QI@1239|Firmicutes,4HJMD@91061|Bacilli,3F69N@33958|Lactobacillaceae 91061|Bacilli C Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 AFLMLIMI_02482 543734.LCABL_19120 4.31e-157 440.0 COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,3F6EM@33958|Lactobacillaceae 91061|Bacilli S Dienelactone hydrolase family mhqD - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2,DLH AFLMLIMI_02483 543734.LCABL_19110 1.93e-243 667.0 COG0346@1|root,COG0346@2|Bacteria,1TP7I@1239|Firmicutes,4H9ND@91061|Bacilli,3F4PB@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily mhqA_2 - - ko:K15975 - - - - ko00000 - - - Glyoxalase AFLMLIMI_02484 543734.LCABL_19100 2.77e-220 607.0 COG0346@1|root,COG0346@2|Bacteria,1VWUR@1239|Firmicutes,4HXTS@91061|Bacilli,3FB66@33958|Lactobacillaceae 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ykcA - - - - - - - - - - - Glyoxalase AFLMLIMI_02485 543734.LCABL_19090 6.63e-127 360.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli,3F46V@33958|Lactobacillaceae 91061|Bacilli S HAD phosphatase, family IIIA yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase AFLMLIMI_02486 543734.LCABL_19080 5e-261 715.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli,3F4JU@33958|Lactobacillaceae 91061|Bacilli S Ribosome biogenesis GTPase YqeH yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 AFLMLIMI_02487 543734.LCABL_19070 3.95e-65 198.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,3F7EW@33958|Lactobacillaceae 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY AFLMLIMI_02488 543734.LCABL_19060 2.72e-157 441.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,3F4D6@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like AFLMLIMI_02489 543734.LCABL_19050 3.21e-142 401.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,3F47C@33958|Lactobacillaceae 91061|Bacilli H Hydrolase, HD family yqeK - - - - - - - - - - - HD AFLMLIMI_02490 543734.LCABL_19040 1.18e-78 234.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,3F7QN@33958|Lactobacillaceae 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS AFLMLIMI_02491 543734.LCABL_19030 4.66e-176 490.0 COG0500@1|root,COG0500@2|Bacteria,1UIVS@1239|Firmicutes,4ISTS@91061|Bacilli,3FBXC@33958|Lactobacillaceae 91061|Bacilli Q ubiE/COQ5 methyltransferase family yccK - - - - - - - - - - - Methyltransf_25 AFLMLIMI_02492 543734.LCABL_19020 4.57e-268 734.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli,3F3QC@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 AFLMLIMI_02493 543734.LCABL_19010 3.82e-128 364.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli,3F61Z@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized ACR, COG1399 ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 AFLMLIMI_02494 543734.LCABL_19000 2.34e-51 163.0 COG3153@1|root,COG3153@2|Bacteria,1VFDX@1239|Firmicutes 1239|Firmicutes S Psort location Cytoplasmic, score - - - - - - - - - - - - DUF3781 AFLMLIMI_02495 543734.LCABL_18990 0.0 927.0 COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,3F3S8@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH gnd - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 AFLMLIMI_02496 543734.LCABL_18980 1.01e-157 442.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli,3F421@33958|Lactobacillaceae 91061|Bacilli K response regulator csrR - - - - - - - - - - - Response_reg,Trans_reg_C AFLMLIMI_02497 543734.LCABL_18970 0.0 1005.0 COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,4HAH5@91061|Bacilli,3F3NU@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase arlS GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K18940 ko02020,map02020 M00716,M00717 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA AFLMLIMI_02498 543734.LCABL_18960 8.99e-229 631.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli,3F3P3@33958|Lactobacillaceae 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP AFLMLIMI_02499 543734.LCABL_18950 4.17e-60 186.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli,3F81R@33958|Lactobacillaceae 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase AFLMLIMI_02500 543734.LCABL_18940 4.47e-178 496.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli,3F3NF@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind AFLMLIMI_02501 543734.LCABL_18930 3.09e-122 348.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli,3F64N@33958|Lactobacillaceae 91061|Bacilli S Metal dependent phosphohydrolases with conserved 'HD' motif. XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD AFLMLIMI_02502 543734.LCABL_18920 1.2e-87 257.0 COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,3F7FK@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator, HxlR family yodB GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - HxlR AFLMLIMI_02503 543734.LCABL_18910 3.55e-259 709.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,3F4NT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d AFLMLIMI_02504 543734.LCABL_18900 0.0 1586.0 COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,3F3V3@33958|Lactobacillaceae 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind AFLMLIMI_02505 543734.LCABL_18880 7.4e-265 727.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli,3F4IG@33958|Lactobacillaceae 91061|Bacilli S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG AFLMLIMI_02506 543734.LCABL_18870 3.43e-148 417.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,3F3KE@33958|Lactobacillaceae 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK AFLMLIMI_02507 543734.LCABL_18860 1.05e-101 295.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,3F4ZF@33958|Lactobacillaceae 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N AFLMLIMI_02508 543734.LCABL_18850 1.82e-163 457.0 COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli,3F5S1@33958|Lactobacillaceae 91061|Bacilli S Cell wall-active antibiotics response 4TMS YvqF yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 AFLMLIMI_02509 543734.LCABL_18840 3.81e-231 639.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,3FC2U@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 AFLMLIMI_02510 543734.LCABL_18830 2.04e-149 421.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,3F4DN@33958|Lactobacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg AFLMLIMI_02511 543734.LCABL_18820 1.15e-71 215.0 COG4841@1|root,COG4841@2|Bacteria,1VEQE@1239|Firmicutes,4HNU2@91061|Bacilli,3F7SB@33958|Lactobacillaceae 91061|Bacilli S Belongs to the HesB IscA family yneR - - - - - - - - - - - Fe-S_biosyn AFLMLIMI_02512 543734.LCABL_18810 0.0 1608.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli,3FC7P@33958|Lactobacillaceae 91061|Bacilli S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO AFLMLIMI_02513 543734.LCABL_18780 0.0 1371.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli,3F3KH@33958|Lactobacillaceae 91061|Bacilli M Penicillin-binding Protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase AFLMLIMI_02514 543734.LCABL_18770 1.56e-156 439.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,3F3WR@33958|Lactobacillaceae 91061|Bacilli S Peptidase, S54 family gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 AFLMLIMI_02515 543734.LCABL_18760 2.28e-53 167.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli,3F83I@33958|Lactobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF910) yqgQ - - - - - - - - - - - DUF910 AFLMLIMI_02516 543734.LCABL_18750 1.13e-228 630.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,3F4F0@33958|Lactobacillaceae 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK AFLMLIMI_02517 543734.LCABL_18740 1.93e-96 280.0 COG0607@1|root,COG0607@2|Bacteria,1VAI7@1239|Firmicutes,4HKCE@91061|Bacilli,3F67E@33958|Lactobacillaceae 91061|Bacilli P Rhodanese-like protein yqhL - - - - - - - - - - - Rhodanese AFLMLIMI_02518 543734.LCABL_18730 3.33e-35 119.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli,3F8C0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 AFLMLIMI_02519 543734.LCABL_18720 3.25e-224 617.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli,3F3XS@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT AFLMLIMI_02520 543734.LCABL_18710 1.65e-304 830.0 COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,3F3PU@33958|Lactobacillaceae 91061|Bacilli P aluminum resistance ynbB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - - - - - - - - - - Met_gamma_lyase AFLMLIMI_02521 543734.LCABL_18700 0.0 1373.0 COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,3F3TV@33958|Lactobacillaceae 91061|Bacilli E Orn/Lys/Arg decarboxylase, C-terminal domain speA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.17,4.1.1.18,4.1.1.19 ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 M00133,M00134 R00462,R00566,R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - OKR_DC_1,OKR_DC_1_C AFLMLIMI_02522 543734.LCABL_18690 1.32e-80 239.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli,3F7RX@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 AFLMLIMI_02523 543734.LCABL_18680 0.0 899.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli,3F41A@33958|Lactobacillaceae 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N AFLMLIMI_02524 543734.LCABL_18670 0.0 1583.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli,3F44E@33958|Lactobacillaceae 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 AFLMLIMI_02527 1423816.BACQ01000007_gene175 1.17e-16 71.6 29QJP@1|root,30BJ9@2|Bacteria,1U87T@1239|Firmicutes,4II5H@91061|Bacilli,3FANH@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02528 543734.LCABL_18620 5.83e-67 203.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,3F6WT@33958|Lactobacillaceae 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p AFLMLIMI_02529 543734.LCABL_18610 1.77e-74 223.0 COG2868@1|root,COG2868@2|Bacteria,1VEQ9@1239|Firmicutes,4HNMV@91061|Bacilli,3F839@33958|Lactobacillaceae 91061|Bacilli J Cysteine protease Prp ysxB - - ko:K07584 - - - - ko00000 - - - Peptidase_Prp AFLMLIMI_02530 543734.LCABL_18600 1.6e-63 194.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,3F6WU@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 AFLMLIMI_02531 543734.LCABL_18590 3.55e-258 707.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,3F4DR@33958|Lactobacillaceae 91061|Bacilli E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 AFLMLIMI_02532 543734.LCABL_18580 6.06e-132 374.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C AFLMLIMI_02533 543734.LCABL_18570 9.44e-99 287.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli,3F71X@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 AFLMLIMI_02534 543734.LCABL_18560 6.72e-88 258.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,3F7KW@33958|Lactobacillaceae 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB AFLMLIMI_02535 543734.LCABL_18550 1.82e-192 535.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,3F46A@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD - 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C AFLMLIMI_02536 543734.LCABL_18540 6.34e-295 808.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli,3F4RE@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 AFLMLIMI_02537 543734.LCABL_18530 1.42e-43 142.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli,3F81K@33958|Lactobacillaceae 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S AFLMLIMI_02538 543734.LCABL_18520 1.28e-189 528.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli,3F436@33958|Lactobacillaceae 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt AFLMLIMI_02539 543734.LCABL_18510 5.46e-195 541.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli,3F45T@33958|Lactobacillaceae 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 AFLMLIMI_02540 543734.LCABL_18500 4.19e-96 280.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli,3F71C@33958|Lactobacillaceae 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C AFLMLIMI_02541 543734.LCABL_18490 0.0 1075.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli,3F43U@33958|Lactobacillaceae 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N AFLMLIMI_02542 543734.LCABL_18470 2.71e-66 201.0 2DKQQ@1|root,30ACZ@2|Bacteria,1U6H7@1239|Firmicutes,4IG9I@91061|Bacilli,3F7X5@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02543 1423816.BACQ01000007_gene192 2.34e-117 340.0 COG1752@1|root,COG1752@2|Bacteria,1UXU0@1239|Firmicutes,4IBIE@91061|Bacilli,3F92T@33958|Lactobacillaceae 91061|Bacilli S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin AFLMLIMI_02544 543734.LCABL_18440 2.52e-148 417.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,3F3X9@33958|Lactobacillaceae 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin AFLMLIMI_02545 543734.LCABL_18430 1.77e-47 152.0 COG1758@1|root,COG1758@2|Bacteria,1VK74@1239|Firmicutes,4HNHS@91061|Bacilli,3F81N@33958|Lactobacillaceae 91061|Bacilli K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 AFLMLIMI_02546 543734.LCABL_18420 9.33e-274 750.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,3F3XX@33958|Lactobacillaceae 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein AFLMLIMI_02547 543734.LCABL_18410 0.0 1590.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,3F3N8@33958|Lactobacillaceae 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII AFLMLIMI_02548 543734.LCABL_18400 1.96e-225 621.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,3F4N7@33958|Lactobacillaceae 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N AFLMLIMI_02549 543734.LCABL_18390 0.0 887.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3F45F@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB AFLMLIMI_02550 543734.LCABL_18380 5.22e-174 485.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,3F4UI@33958|Lactobacillaceae 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 AFLMLIMI_02551 543734.LCABL_18370 0.0 1184.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase AFLMLIMI_02552 543734.LCABL_18360 5.6e-221 608.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli,3F3XH@33958|Lactobacillaceae 91061|Bacilli S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N AFLMLIMI_02553 543734.LCABL_18350 4.16e-151 425.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,3F4KX@33958|Lactobacillaceae 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim AFLMLIMI_02554 543734.LCABL_18340 5.08e-164 458.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,3F4N8@33958|Lactobacillaceae 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic AFLMLIMI_02555 543734.LCABL_18330 2.29e-36 122.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli,3F7ZN@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 AFLMLIMI_02556 543734.LCABL_18320 5.83e-75 224.0 COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,3F72W@33958|Lactobacillaceae 91061|Bacilli S Asp23 family, cell envelope-related function yloU - - - - - - - - - - - Asp23 AFLMLIMI_02557 543734.LCABL_18310 0.0 1067.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli,3F3X0@33958|Lactobacillaceae 91061|Bacilli S DAK2 domain fusion protein YloV yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 AFLMLIMI_02558 543734.LCABL_18300 0.0 1316.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,3F3JW@33958|Lactobacillaceae 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge AFLMLIMI_02559 543734.LCABL_18290 1.11e-238 657.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli,3F4N9@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis AFLMLIMI_02560 543734.LCABL_18280 1.31e-48 155.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,3F7F4@33958|Lactobacillaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding AFLMLIMI_02561 543734.LCABL_18270 4.24e-247 678.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,3F41T@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppD GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY AFLMLIMI_02562 543734.LCABL_18260 1.62e-228 629.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli,3F4GM@33958|Lactobacillaceae 91061|Bacilli P Belongs to the ABC transporter superfamily oppF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY AFLMLIMI_02563 1423816.BACQ01000007_gene212 3.2e-216 598.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,3FCCU@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease oppB - - ko:K02033,ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 AFLMLIMI_02564 543734.LCABL_18230 1.65e-193 539.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HA7I@91061|Bacilli,3FCB6@33958|Lactobacillaceae 91061|Bacilli EP Binding-protein-dependent transport system inner membrane component oppC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N AFLMLIMI_02565 1423732.BALS01000003_gene898 0.0 1117.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,3F3KW@33958|Lactobacillaceae 91061|Bacilli E ABC transporter substrate-binding protein oppA1 - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 AFLMLIMI_02566 543734.LCABL_18210 2.8e-161 452.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,3F564@33958|Lactobacillaceae 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm AFLMLIMI_02567 543734.LCABL_18200 0.0 1156.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge AFLMLIMI_02568 543734.LCABL_18200 0.0 931.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge AFLMLIMI_02569 543734.LCABL_18190 4.3e-231 637.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli,3F3YC@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N AFLMLIMI_02570 543734.LCABL_18180 7.91e-70 210.0 2EU16@1|root,33MI8@2|Bacteria,1VPSM@1239|Firmicutes,4HS7T@91061|Bacilli,3F6QA@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02572 543734.LCABL_18170 1.26e-75 226.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli,3F7FG@33958|Lactobacillaceae 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 AFLMLIMI_02573 543734.LCABL_18160 2.16e-303 832.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli,3F40R@33958|Lactobacillaceae 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB AFLMLIMI_02574 543734.LCABL_18150 2.97e-59 182.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 AFLMLIMI_02575 543734.LCABL_18140 1.55e-51 162.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,4HNX0@91061|Bacilli,3F829@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 AFLMLIMI_02576 543734.LCABL_18120 2.16e-120 343.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,3F74P@33958|Lactobacillaceae 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM AFLMLIMI_02577 543734.LCABL_18110 1.76e-185 515.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,3F3NP@33958|Lactobacillaceae 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT AFLMLIMI_02578 543734.LCABL_18100 2e-75 225.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 AFLMLIMI_02579 568703.LGG_01638 3.28e-28 102.0 29QDP@1|root,30BCZ@2|Bacteria,1U7XM@1239|Firmicutes,4IHV0@91061|Bacilli,3FAAR@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02580 543734.LCABL_18080 2.84e-48 154.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli,3F87S@33958|Lactobacillaceae 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 AFLMLIMI_02581 543734.LCABL_18070 1.39e-40 134.0 COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,4HNN9@91061|Bacilli,3FCDQ@33958|Lactobacillaceae 91061|Bacilli S UPF0154 protein yneF - - ko:K09976 - - - - ko00000 - - - UPF0154 AFLMLIMI_02582 543734.LCABL_18060 0.0 1139.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran AFLMLIMI_02583 543734.LCABL_18050 0.0 1135.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran AFLMLIMI_02585 543734.LCABL_18040 1.32e-177 496.0 COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli,3F4FJ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1003) yejC - - - - - - - - - - - DUF1003 AFLMLIMI_02586 543734.LCABL_18030 1.59e-291 801.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,3F3QY@33958|Lactobacillaceae 91061|Bacilli E Amino Acid yhdG - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 AFLMLIMI_02587 543734.LCABL_18020 6.95e-159 444.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,3F4QB@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase AFLMLIMI_02588 543734.LCABL_18010 2.05e-168 471.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli,3F4C5@33958|Lactobacillaceae 91061|Bacilli L Methyltransferase small domain yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS AFLMLIMI_02589 543734.LCABL_18000 5.38e-61 187.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,3F7G2@33958|Lactobacillaceae 91061|Bacilli L GIY-YIG catalytic domain protein yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG AFLMLIMI_02590 543734.LCABL_17990 1.18e-182 508.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 AFLMLIMI_02591 543734.LCABL_17980 1.63e-200 556.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli,3F459@33958|Lactobacillaceae 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS AFLMLIMI_02592 543734.LCABL_17970 5.86e-167 467.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,3F42J@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase AFLMLIMI_02593 543734.LCABL_17960 4.96e-121 346.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,3F4X2@33958|Lactobacillaceae 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF AFLMLIMI_02594 543734.LCABL_17950 5.24e-180 501.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,3F42M@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf AFLMLIMI_02595 543734.LCABL_17940 7.66e-179 499.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,3FC0H@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 AFLMLIMI_02596 543734.LCABL_17930 7.09e-292 797.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli,3F3TM@33958|Lactobacillaceae 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 AFLMLIMI_02597 543734.LCABL_17920 0.0 1110.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,3F44A@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit AFLMLIMI_02598 543734.LCABL_17910 0.0 2859.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli,3F4AN@33958|Lactobacillaceae 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon AFLMLIMI_02599 543734.LCABL_17900 1.33e-110 318.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,3F6GZ@33958|Lactobacillaceae 91061|Bacilli J Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C AFLMLIMI_02600 543734.LCABL_17890 1.68e-276 759.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli,3F3KZ@33958|Lactobacillaceae 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 AFLMLIMI_02601 543734.LCABL_17880 9.63e-61 187.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli,3F7E2@33958|Lactobacillaceae 91061|Bacilli K Protein of unknown function (DUF448) ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 AFLMLIMI_02602 543734.LCABL_17870 1.29e-60 187.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,3F7ZK@33958|Lactobacillaceae 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae AFLMLIMI_02603 543734.LCABL_17860 0.0 1574.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,3F3JV@33958|Lactobacillaceae 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N AFLMLIMI_02604 1423732.BALS01000003_gene941 1.27e-76 229.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,3F6WZ@33958|Lactobacillaceae 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA AFLMLIMI_02605 543734.LCABL_17840 8.79e-181 508.0 COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4HB99@91061|Bacilli,3FB68@33958|Lactobacillaceae 91061|Bacilli P Integral membrane protein TerC family terC - - - - - - - - - - - TerC AFLMLIMI_02606 543734.LCABL_17830 9.47e-212 585.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli,3F3NX@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N AFLMLIMI_02607 543734.LCABL_17820 6.32e-225 620.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli,3F3TG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase AFLMLIMI_02608 543734.LCABL_17810 8.81e-288 784.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,3F4BA@33958|Lactobacillaceae 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM AFLMLIMI_02609 543734.LCABL_17800 1.6e-246 677.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli,3F3ST@33958|Lactobacillaceae 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg AFLMLIMI_02610 543734.LCABL_17790 3.18e-127 363.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,3F4DY@33958|Lactobacillaceae 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE AFLMLIMI_02611 543734.LCABL_17780 0.0 1181.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli,3F48C@33958|Lactobacillaceae 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 AFLMLIMI_02612 543734.LCABL_17770 9.45e-261 716.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,3F490@33958|Lactobacillaceae 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG AFLMLIMI_02613 543734.LCABL_17760 0.0 1188.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,3F3Z1@33958|Lactobacillaceae 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C AFLMLIMI_02614 1423816.BACQ01000009_gene262 1.32e-33 117.0 2AI13@1|root,318EQ@2|Bacteria,1U7VD@1239|Firmicutes,4IHST@91061|Bacilli,3FA82@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02615 543734.LCABL_17740 2.05e-109 315.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,3F7EV@33958|Lactobacillaceae 91061|Bacilli S ASCH - - - - - - - - - - - - ASCH AFLMLIMI_02616 1423816.BACQ01000009_gene264 2.17e-76 228.0 29PHG@1|root,30AFM@2|Bacteria,1U6KN@1239|Firmicutes,4IGDE@91061|Bacilli,3F83U@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02617 543734.LCABL_17720 0.0 1477.0 COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,3F42C@33958|Lactobacillaceae 91061|Bacilli L Single-stranded-DNA-specific exonuclease RecJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C AFLMLIMI_02618 543734.LCABL_17710 1.7e-123 352.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli,3F4DB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran AFLMLIMI_02619 543734.LCABL_17700 2.35e-117 335.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HHVB@91061|Bacilli,3F5H1@33958|Lactobacillaceae 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily ybaK - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit AFLMLIMI_02620 543734.LCABL_17690 6.77e-71 213.0 2ED3T@1|root,3370N@2|Bacteria,1VIJK@1239|Firmicutes,4HPGM@91061|Bacilli,3F765@33958|Lactobacillaceae 91061|Bacilli S Staphylococcal protein of unknown function (DUF960) XK27_08430 - - - - - - - - - - - DUF960 AFLMLIMI_02621 543734.LCABL_17680 7.18e-191 530.0 COG3741@1|root,COG3741@2|Bacteria,1V6B3@1239|Firmicutes,4HQ4E@91061|Bacilli,3F6V6@33958|Lactobacillaceae 91061|Bacilli E N-formylglutamate amidohydrolase hutG - 3.5.3.8 ko:K01479 ko00340,ko01100,map00340,map01100 M00045 R02285 RC00221,RC00681 ko00000,ko00001,ko00002,ko01000 - - - FGase AFLMLIMI_02622 543734.LCABL_17670 9.6e-125 356.0 COG1309@1|root,COG1309@2|Bacteria,1W6HU@1239|Firmicutes,4HY6F@91061|Bacilli,3F6V3@33958|Lactobacillaceae 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N AFLMLIMI_02623 543734.LCABL_17660 8.54e-141 397.0 COG2249@1|root,COG2249@2|Bacteria,1VB36@1239|Firmicutes,4HW64@91061|Bacilli,3F66F@33958|Lactobacillaceae 91061|Bacilli S Flavodoxin-like fold - - - - - - - - - - - - Flavodoxin_2 AFLMLIMI_02625 543734.LCABL_17640 1.67e-110 318.0 COG0454@1|root,COG0456@2|Bacteria,1V3K1@1239|Firmicutes,4HHY4@91061|Bacilli,3F91N@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 AFLMLIMI_02626 568703.LGG_01578 1.72e-64 199.0 29PAD@1|root,30A8I@2|Bacteria,1U6BX@1239|Firmicutes,4IG3I@91061|Bacilli,3F7JN@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02627 568703.LGG_01577 5.6e-27 99.0 29QDN@1|root,30BCY@2|Bacteria,1U7XK@1239|Firmicutes,4IHUZ@91061|Bacilli,3FAAQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02628 1045004.OKIT_0978 0.0 1967.0 COG0286@1|root,COG1111@1|root,COG4889@1|root,COG0286@2|Bacteria,COG1111@2|Bacteria,COG4889@2|Bacteria,1W6ZM@1239|Firmicutes,4I4P0@91061|Bacilli,4AYSG@81850|Leuconostocaceae 91061|Bacilli L helicase - - - - - - - - - - - - - AFLMLIMI_02629 1329250.WOSG25_090340 1.17e-98 292.0 COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,4HBVE@91061|Bacilli 91061|Bacilli D Fic/DOC family fic - - ko:K04095 - - - - ko00000,ko03036 - - - Fic AFLMLIMI_02630 543734.LCABL_17610 6.62e-87 255.0 COG5294@1|root,COG5294@2|Bacteria,1W0J9@1239|Firmicutes,4HYK1@91061|Bacilli,3F8AZ@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 AFLMLIMI_02631 543734.LCABL_17600 2.23e-50 159.0 29QBB@1|root,30BAI@2|Bacteria,1U7TK@1239|Firmicutes,4IHR2@91061|Bacilli,3FA5R@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02632 543734.LCABL_17590 2.98e-142 401.0 COG2094@1|root,COG2094@2|Bacteria,1V1E6@1239|Firmicutes,4HJ10@91061|Bacilli,3FC7N@33958|Lactobacillaceae 91061|Bacilli L Belongs to the DNA glycosylase MPG family - GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 ko:K03652 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Pur_DNA_glyco AFLMLIMI_02633 543734.LCABL_17580 4.08e-112 322.0 2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli,3F6FP@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF3013) XK27_03960 - - - - - - - - - - - DUF3013 AFLMLIMI_02634 543734.LCABL_17570 1.74e-222 613.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,3F47Z@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA AFLMLIMI_02635 543734.LCABL_17560 5.19e-169 473.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,3F64Z@33958|Lactobacillaceae 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA AFLMLIMI_02636 1423732.BALS01000048_gene2576 4.52e-57 178.0 2DKTI@1|root,30ARB@2|Bacteria,1U70F@1239|Firmicutes,4IGUR@91061|Bacilli,3F8T9@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02637 543734.LCABL_17540 0.0 1469.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli,3F44F@33958|Lactobacillaceae 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS AFLMLIMI_02638 543734.LCABL_17530 1.86e-98 286.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,3F6GK@33958|Lactobacillaceae 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase AFLMLIMI_02639 543734.LCABL_17520 2.24e-149 420.0 COG0546@1|root,COG0546@2|Bacteria,1V3DR@1239|Firmicutes,4HGMU@91061|Bacilli,3F741@33958|Lactobacillaceae 91061|Bacilli J HAD-hyrolase-like - - - - - - - - - - - - HAD_2 AFLMLIMI_02640 543734.LCABL_17510 8.06e-314 855.0 COG0860@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,3F4F4@33958|Lactobacillaceae 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytH GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3 AFLMLIMI_02641 543734.LCABL_17500 9.64e-109 312.0 COG0537@1|root,COG0537@2|Bacteria,1V5XZ@1239|Firmicutes,4HHN5@91061|Bacilli,3FCAY@33958|Lactobacillaceae 91061|Bacilli FG adenosine 5'-monophosphoramidase activity - - - - - - - - - - - - HIT AFLMLIMI_02642 543734.LCABL_17490 2.21e-197 548.0 COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,4HFS1@91061|Bacilli,3F52V@33958|Lactobacillaceae 91061|Bacilli V ABC transporter - - - - - - - - - - - - ABC_tran AFLMLIMI_02643 543734.LCABL_17480 0.0 957.0 2DV5N@1|root,33U6G@2|Bacteria,1VUTX@1239|Firmicutes,4HVQT@91061|Bacilli,3FBQP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02644 543734.LCABL_17440 4.56e-47 152.0 COG0221@1|root,COG0221@2|Bacteria,1VB6Q@1239|Firmicutes,4HKI4@91061|Bacilli,3F81A@33958|Lactobacillaceae 91061|Bacilli C Inorganic pyrophosphatase XK27_04345 - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase AFLMLIMI_02645 543734.LCABL_17430 9.36e-296 808.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli,3F3M3@33958|Lactobacillaceae 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA-synt_His AFLMLIMI_02646 543734.LCABL_17420 0.0 1204.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli,3F4PE@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon AFLMLIMI_02647 543734.LCABL_17410 8.83e-107 307.0 COG0229@1|root,COG0229@2|Bacteria,1UPN0@1239|Firmicutes,4HGWN@91061|Bacilli,3F6H4@33958|Lactobacillaceae 91061|Bacilli O peptide methionine sulfoxide reductase msrB - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR AFLMLIMI_02648 543734.LCABL_17400 3.1e-216 597.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli,3F3PH@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 yitT - - - - - - - - - - - DUF2179,YitT_membrane AFLMLIMI_02649 543734.LCABL_17390 2.03e-209 578.0 COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,4HB4F@91061|Bacilli,3F42I@33958|Lactobacillaceae 91061|Bacilli L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin nfo GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 AFLMLIMI_02650 543734.LCABL_17380 8.44e-199 550.0 COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4HB0Q@91061|Bacilli,3F3WK@33958|Lactobacillaceae 91061|Bacilli F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation yqfL - 2.7.11.33,2.7.4.28 ko:K09773 - - - - ko00000,ko01000 - - - Kinase-PPPase AFLMLIMI_02651 543734.LCABL_17370 3.98e-29 104.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli,3F81Y@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 AFLMLIMI_02652 543734.LCABL_17360 1.81e-88 261.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,3F6I0@33958|Lactobacillaceae 91061|Bacilli S YqeY-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY AFLMLIMI_02654 543734.LCABL_17350 8.02e-230 633.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,3F4E7@33958|Lactobacillaceae 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH AFLMLIMI_02655 543734.LCABL_17340 1.03e-106 307.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,3F516@33958|Lactobacillaceae 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 AFLMLIMI_02656 543734.LCABL_17330 6.78e-82 243.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,3F7DC@33958|Lactobacillaceae 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar AFLMLIMI_02657 543734.LCABL_17320 1.38e-84 249.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli,3F7RM@33958|Lactobacillaceae 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 AFLMLIMI_02658 543734.LCABL_17310 2.76e-216 597.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,3F3WQ@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 AFLMLIMI_02659 543734.LCABL_17300 1e-181 505.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli,3F56P@33958|Lactobacillaceae 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N AFLMLIMI_02660 543734.LCABL_17290 1.04e-69 210.0 2C8G2@1|root,348DR@2|Bacteria,1VZDC@1239|Firmicutes,4HZ47@91061|Bacilli,3F740@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02661 543734.LCABL_17280 2.89e-71 214.0 2C8G2@1|root,348DR@2|Bacteria,1VZDC@1239|Firmicutes,4HZ47@91061|Bacilli,3F740@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02662 568703.LGG_01514 3e-219 604.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli,3F3T8@33958|Lactobacillaceae 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e AFLMLIMI_02663 543734.LCABL_17260 0.0 1347.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli,3F4G8@33958|Lactobacillaceae 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f AFLMLIMI_02664 543734.LCABL_17250 0.0 1125.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 AFLMLIMI_02665 543734.LCABL_17240 9.19e-249 689.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,3F4CF@33958|Lactobacillaceae 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 AFLMLIMI_02666 543734.LCABL_17220 3.25e-160 449.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli,3F4GT@33958|Lactobacillaceae 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK AFLMLIMI_02667 543734.LCABL_17210 1.4e-191 531.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli,3F3ZD@33958|Lactobacillaceae 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 AFLMLIMI_02668 543734.LCABL_17200 2.03e-35 120.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli,3F83T@33958|Lactobacillaceae 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase AFLMLIMI_02669 543734.LCABL_17190 2.32e-79 235.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,3F7D5@33958|Lactobacillaceae 91061|Bacilli S Iron-sulfur cluster assembly protein yitW - - - - - - - - - - - DUF1858,FeS_assembly_P AFLMLIMI_02670 543734.LCABL_17180 2.61e-183 509.0 2E39Q@1|root,32Y99@2|Bacteria,1VQQ8@1239|Firmicutes,4HRY1@91061|Bacilli,3F4UX@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02671 543734.LCABL_17170 1.54e-222 614.0 2EPHD@1|root,33H40@2|Bacteria,1VNCY@1239|Firmicutes,4HYY7@91061|Bacilli,3F495@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - MacB_PCD AFLMLIMI_02672 543734.LCABL_17160 0.0 907.0 COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli,3F492@33958|Lactobacillaceae 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI AFLMLIMI_02673 543734.LCABL_17150 1.53e-242 667.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli,3F3UY@33958|Lactobacillaceae 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh AFLMLIMI_02674 543734.LCABL_17140 3.82e-231 637.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli,3F4B5@33958|Lactobacillaceae 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N AFLMLIMI_02675 543734.LCABL_17130 2.26e-216 598.0 COG1577@1|root,COG1577@2|Bacteria,1TT5C@1239|Firmicutes,4HAQQ@91061|Bacilli,3F3TW@33958|Lactobacillaceae 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N AFLMLIMI_02676 543734.LCABL_17120 0.0 2315.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli,3F3RS@33958|Lactobacillaceae 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C AFLMLIMI_02677 543734.LCABL_17110 0.0 2378.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,3F3Z0@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C AFLMLIMI_02678 543734.LCABL_17100 0.0 1761.0 COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,3F4KA@33958|Lactobacillaceae 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII AFLMLIMI_02680 543734.LCABL_17090 3.5e-112 322.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli,3F4MM@33958|Lactobacillaceae 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY AFLMLIMI_02681 543734.LCABL_17080 1.9e-278 761.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli,3F3MX@33958|Lactobacillaceae 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_02682 543734.LCABL_17070 0.0 896.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,3F4EK@33958|Lactobacillaceae 91061|Bacilli J Asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon AFLMLIMI_02683 543734.LCABL_17060 3.19e-146 412.0 COG3935@1|root,COG3935@2|Bacteria,1V283@1239|Firmicutes,4HFP3@91061|Bacilli,3F4FF@33958|Lactobacillaceae 91061|Bacilli L DnaD domain protein dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 AFLMLIMI_02684 543734.LCABL_17050 7.61e-148 417.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,3F42U@33958|Lactobacillaceae 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD AFLMLIMI_02685 543734.LCABL_17040 5.94e-111 318.0 COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,4HCDG@91061|Bacilli,3F6BF@33958|Lactobacillaceae 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 AFLMLIMI_02686 543734.LCABL_17030 0.0 1385.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,3F424@33958|Lactobacillaceae 91061|Bacilli M penicillin-binding protein 1A ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 AFLMLIMI_02687 543734.LCABL_17020 4.21e-156 437.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli,3F4DG@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU AFLMLIMI_02688 543734.LCABL_17010 9.29e-138 389.0 COG4474@1|root,COG4474@2|Bacteria,1V6SM@1239|Firmicutes,4HJGM@91061|Bacilli,3F4MR@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 AFLMLIMI_02689 543734.LCABL_17000 7.09e-88 258.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli,3F6VZ@33958|Lactobacillaceae 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA AFLMLIMI_02690 543734.LCABL_16990 2.31e-278 760.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli,3F3NZ@33958|Lactobacillaceae 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 AFLMLIMI_02691 543734.LCABL_16980 5.8e-219 604.0 COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,4HAW5@91061|Bacilli,3F4DF@33958|Lactobacillaceae 91061|Bacilli EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C AFLMLIMI_02692 543734.LCABL_16970 8.85e-47 150.0 2CDEF@1|root,30AS2@2|Bacteria,1U71A@1239|Firmicutes,4IGVR@91061|Bacilli,3F8UP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02693 543734.LCABL_16960 1e-248 682.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli,3F4UZ@33958|Lactobacillaceae 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C AFLMLIMI_02694 543734.LCABL_16950 0.0 1269.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli,3F4CX@33958|Lactobacillaceae 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N AFLMLIMI_02695 543734.LCABL_16940 9.5e-207 572.0 COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HAZB@91061|Bacilli,3F3VP@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator lysR - - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_02696 543734.LCABL_16930 8.83e-242 663.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli,3F3P1@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm AFLMLIMI_02697 543734.LCABL_16920 0.0 1441.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli,3F3XG@33958|Lactobacillaceae 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN AFLMLIMI_02698 543734.LCABL_16910 8.72e-52 162.0 COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli,3F874@33958|Lactobacillaceae 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin AFLMLIMI_02699 543734.LCABL_16900 0.0 951.0 2C9BC@1|root,2ZI2Q@2|Bacteria,1TVHZ@1239|Firmicutes,4I07N@91061|Bacilli 91061|Bacilli S Mga helix-turn-helix domain - - - - - - - - - - - - Mga AFLMLIMI_02700 568703.LGG_01471 3.85e-63 194.0 29PM1@1|root,30AJ7@2|Bacteria,1U6RT@1239|Firmicutes,4IGJ9@91061|Bacilli,3F8DQ@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02701 543734.LCABL_16880 0.0 964.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli,3F3SF@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N AFLMLIMI_02702 543734.LCABL_16860 2.09e-143 404.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli,3F576@33958|Lactobacillaceae 91061|Bacilli S Nitroreductase family XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase AFLMLIMI_02703 543734.LCABL_16850 2.37e-91 267.0 COG0328@1|root,COG0328@2|Bacteria,1VH2B@1239|Firmicutes,4HIY9@91061|Bacilli,3F7JC@33958|Lactobacillaceae 91061|Bacilli L Ribonuclease HI rnhA - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H,RVT_3 AFLMLIMI_02704 1423732.BALS01000002_gene1011 1.21e-60 189.0 2BF1V@1|root,328TS@2|Bacteria,1UUT0@1239|Firmicutes,4IHGJ@91061|Bacilli,3F9TN@33958|Lactobacillaceae 91061|Bacilli S Family of unknown function (DUF5322) - - - - - - - - - - - - DUF5322 AFLMLIMI_02705 543734.LCABL_16830 0.0 1095.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli,3F3U6@33958|Lactobacillaceae 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS AFLMLIMI_02706 543734.LCABL_16820 2.41e-106 306.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,3F66R@33958|Lactobacillaceae 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 AFLMLIMI_02707 543734.LCABL_16810 3.64e-222 612.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli,3F3P6@33958|Lactobacillaceae 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 AFLMLIMI_02708 543734.LCABL_16800 1.05e-125 358.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli,3F4SR@33958|Lactobacillaceae 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran AFLMLIMI_02709 543734.LCABL_16790 1.64e-299 818.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli,3F3UJ@33958|Lactobacillaceae 91061|Bacilli F Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease AFLMLIMI_02710 543734.LCABL_16780 7.64e-229 630.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli,3F4BQ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N AFLMLIMI_02711 543734.LCABL_16770 5.13e-305 831.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli,3F3S3@33958|Lactobacillaceae 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 AFLMLIMI_02712 543734.LCABL_16760 5.32e-267 730.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli,3F43R@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase AFLMLIMI_02713 543734.LCABL_16750 0.0 2049.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,3F3MD@33958|Lactobacillaceae 91061|Bacilli F Carbamoyl-phosphate synthase carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS AFLMLIMI_02714 543734.LCABL_16740 2.13e-197 548.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli,3F4PJ@33958|Lactobacillaceae 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh AFLMLIMI_02715 543734.LCABL_16730 3.64e-161 452.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli,3F47Y@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AFLMLIMI_02716 543734.LCABL_16720 8.37e-145 409.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,3F487@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran AFLMLIMI_02717 543734.LCABL_16710 1.01e-189 528.0 COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4HBSK@91061|Bacilli,3F7SC@33958|Lactobacillaceae 91061|Bacilli C Phosphate acetyl/butaryl transferase ptb - 2.3.1.19 ko:K00634 ko00650,ko01100,map00650,map01100 - R01174 RC00004,RC02816 ko00000,ko00001,ko01000 - - - PTA_PTB AFLMLIMI_02718 543734.LCABL_16700 9.11e-261 715.0 COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,4H9QV@91061|Bacilli,3F6TG@33958|Lactobacillaceae 91061|Bacilli C Acetokinase family buk - 2.7.2.7 ko:K00929 ko00650,ko01100,map00650,map01100 - R01688 RC00002,RC00043 ko00000,ko00001,ko01000 - - - Acetate_kinase AFLMLIMI_02719 543734.LCABL_16690 0.0 903.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli,3F5YW@33958|Lactobacillaceae 91061|Bacilli C 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bfmBC - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim AFLMLIMI_02720 543734.LCABL_16680 9.14e-239 656.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,3F55B@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase E1 component bfmBAA - 1.2.4.4 ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07640 E1_dh AFLMLIMI_02721 543734.LCABL_16670 2.14e-234 645.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,3F4TD@33958|Lactobacillaceae 91061|Bacilli C Transketolase, pyrimidine binding domain bfmBAB - 1.2.4.4 ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU24040 Transket_pyr,Transketolase_C AFLMLIMI_02722 543734.LCABL_16660 9.61e-289 791.0 COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,3F7YX@33958|Lactobacillaceae 91061|Bacilli C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) bfmBB - 2.3.1.12,2.3.1.168 ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 M00036,M00307 R00209,R02569,R02662,R03174,R04097,R10998 RC00004,RC02727,RC02742,RC02857,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding AFLMLIMI_02723 543734.LCABL_16650 2.13e-227 626.0 COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,4HBPD@91061|Bacilli,3FCCS@33958|Lactobacillaceae 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid panE - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C AFLMLIMI_02724 543734.LCABL_16640 8.21e-250 688.0 COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,4HAK5@91061|Bacilli,3FCB4@33958|Lactobacillaceae 91061|Bacilli S Phosphotransferase system, EIIC pfoS/R - - ko:K07035 - - - - ko00000 - - - PTS_EIIC_2 AFLMLIMI_02725 543734.LCABL_16630 8.55e-67 202.0 COG1694@1|root,COG1694@2|Bacteria,1VJNA@1239|Firmicutes,4I1AJ@91061|Bacilli 91061|Bacilli S MazG-like family - - - - - - - - - - - - MazG-like AFLMLIMI_02726 543734.LCABL_16620 0.0 1108.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli,3F3PS@33958|Lactobacillaceae 91061|Bacilli K Fibronectin-binding protein FbpA - - - - - - - - - - - DUF814,FbpA AFLMLIMI_02727 543734.LCABL_16610 2.95e-205 568.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,3F40W@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV AFLMLIMI_02728 543734.LCABL_16600 1.94e-128 365.0 COG0494@1|root,COG0494@2|Bacteria,1VXC7@1239|Firmicutes,4HX58@91061|Bacilli,3F45R@33958|Lactobacillaceae 91061|Bacilli L Belongs to the Nudix hydrolase family - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX AFLMLIMI_02729 543734.LCABL_16580 5.7e-260 712.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_02730 543734.LCABL_16570 3.15e-277 758.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli,3F4W1@33958|Lactobacillaceae 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His AFLMLIMI_02731 543734.LCABL_16560 2.06e-144 407.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli,3F4WT@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His AFLMLIMI_02732 543734.LCABL_16550 2.79e-293 802.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,3F40P@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh AFLMLIMI_02733 543734.LCABL_16540 9.22e-135 382.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli,3F4TQ@33958|Lactobacillaceae 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD AFLMLIMI_02734 543734.LCABL_16530 4.89e-146 411.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHSP@91061|Bacilli,3FBCG@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase AFLMLIMI_02735 543734.LCABL_16520 3.77e-158 444.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli,3F5YT@33958|Lactobacillaceae 91061|Bacilli E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth AFLMLIMI_02736 543734.LCABL_16510 4.08e-169 473.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli,3F3XV@33958|Lactobacillaceae 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth AFLMLIMI_02737 543734.LCABL_16500 1.01e-77 231.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,3F73W@33958|Lactobacillaceae 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH AFLMLIMI_02738 543734.LCABL_16490 6.09e-70 211.0 COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,4HKDY@91061|Bacilli,3F7V5@33958|Lactobacillaceae 91061|Bacilli E phosphoribosyl-ATP diphosphatase activity hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH AFLMLIMI_02739 543734.LCABL_16480 4.87e-260 712.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli,3F466@33958|Lactobacillaceae 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 AFLMLIMI_02740 543734.LCABL_16470 2.92e-144 407.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HYXD@91061|Bacilli 91061|Bacilli C Nitroreductase family - - - - - - - - - - - - Nitroreductase AFLMLIMI_02741 543734.LCABL_16460 1.73e-93 272.0 COG0454@1|root,COG0456@2|Bacteria,1UVU0@1239|Firmicutes,4IG71@91061|Bacilli,3F7S8@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 AFLMLIMI_02742 568703.LGG_01431 1.06e-64 199.0 COG0454@1|root,COG0456@2|Bacteria,1UI3A@1239|Firmicutes,4ISBV@91061|Bacilli,3F83Y@33958|Lactobacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10 AFLMLIMI_02743 543734.LCABL_16440 6.44e-242 668.0 COG0477@1|root,COG0477@2|Bacteria,1UHRM@1239|Firmicutes,4ISTP@91061|Bacilli,3FBXB@33958|Lactobacillaceae 91061|Bacilli EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1 AFLMLIMI_02744 543734.LCABL_16430 6.83e-157 441.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HIBI@91061|Bacilli,3FC95@33958|Lactobacillaceae 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C AFLMLIMI_02745 543734.LCABL_16420 3.48e-219 605.0 COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,4HFQK@91061|Bacilli,3F5QR@33958|Lactobacillaceae 91061|Bacilli T Histidine kinase-like ATPases kinG - - - - - - - - - - - HATPase_c AFLMLIMI_02746 543734.LCABL_16410 2.68e-176 492.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3F3MG@33958|Lactobacillaceae 91061|Bacilli V ABC transporter, ATP-binding protein XK27_05695 - - ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - ABC_tran AFLMLIMI_02747 543734.LCABL_16400 0.0 1230.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli,3FBRY@33958|Lactobacillaceae 91061|Bacilli V FtsX-like permease family XK27_05700 - - ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - FtsX AFLMLIMI_02748 543734.LCABL_16390 7.18e-79 234.0 2E4BT@1|root,33YQ0@2|Bacteria,1VWQW@1239|Firmicutes,4HWWB@91061|Bacilli,3FBRI@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02749 543734.LCABL_16380 6.01e-269 736.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli,3FBHV@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase AFLMLIMI_02750 641146.HMPREF9020_01154 4.51e-300 818.0 COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4D1TR@85004|Bifidobacteriales 201174|Actinobacteria L Transposase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_02751 543734.LCABL_16370 3.78e-219 605.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli,3F3PJ@33958|Lactobacillaceae 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 AFLMLIMI_02752 543734.LCABL_16360 2.6e-232 639.0 COG0583@1|root,COG0583@2|Bacteria,1UYRT@1239|Firmicutes,4IQQ1@91061|Bacilli,3FBIB@33958|Lactobacillaceae 91061|Bacilli K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate AFLMLIMI_02753 543734.LCABL_16350 2.56e-217 598.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli,3F472@33958|Lactobacillaceae 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM AFLMLIMI_02754 543734.LCABL_16340 0.0 1533.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli,3F53K@33958|Lactobacillaceae 91061|Bacilli C Pyruvate formate lyase-like pflB GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like AFLMLIMI_02755 543734.LCABL_16330 0.0 1580.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli,3F3MJ@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV AFLMLIMI_02756 543734.LCABL_16320 0.0 1316.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli,3F430@33958|Lactobacillaceae 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim AFLMLIMI_02757 543734.LCABL_16310 6.92e-141 398.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,3F543@33958|Lactobacillaceae 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf AFLMLIMI_02758 543734.LCABL_16300 1.27e-217 599.0 COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,4HA4J@91061|Bacilli,3F3KT@33958|Lactobacillaceae 91061|Bacilli G Aldose 1-epimerase lacX - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim AFLMLIMI_02759 543734.LCABL_16290 0.0 892.0 COG1220@1|root,COG1220@2|Bacteria,1TPKQ@1239|Firmicutes,4HA83@91061|Bacilli,3F3WB@33958|Lactobacillaceae 91061|Bacilli O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small AFLMLIMI_02760 543734.LCABL_16280 2.06e-119 341.0 COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,4H9PD@91061|Bacilli,3F4HS@33958|Lactobacillaceae 91061|Bacilli O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome AFLMLIMI_02761 543734.LCABL_16270 1.66e-216 597.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,3F44K@33958|Lactobacillaceae 91061|Bacilli D Belongs to the 'phage' integrase family. XerC subfamily xerC - - ko:K03733,ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase AFLMLIMI_02762 543734.LCABL_16260 0.0 864.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,3F3WW@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA AFLMLIMI_02763 543734.LCABL_16250 0.0 1353.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli,3F3VS@33958|Lactobacillaceae 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom AFLMLIMI_02764 543734.LCABL_16230 1.1e-187 522.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli,3F41U@33958|Lactobacillaceae 91061|Bacilli LU DNA protecting protein DprA dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A AFLMLIMI_02765 543734.LCABL_16220 1.97e-176 492.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3F3JC@33958|Lactobacillaceae 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII AFLMLIMI_02766 543734.LCABL_16210 5.1e-205 567.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli,3F3MI@33958|Lactobacillaceae 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 AFLMLIMI_02767 543734.LCABL_16190 8.99e-64 201.0 COG1396@1|root,COG1396@2|Bacteria,1TSJ6@1239|Firmicutes,4HC63@91061|Bacilli,3F6KA@33958|Lactobacillaceae 91061|Bacilli K Helix-turn-helix domain - - - - - - - - - - - - HTH_31 AFLMLIMI_02768 543734.LCABL_16150 1.72e-316 865.0 COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,3F3SS@33958|Lactobacillaceae 91061|Bacilli M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ,PDZ_2,PG_binding_1,Peptidase_S41 AFLMLIMI_02769 543734.LCABL_16140 2.95e-54 169.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli,3F7ZP@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like AFLMLIMI_02770 543734.LCABL_16130 3.02e-111 319.0 COG0225@1|root,COG0225@2|Bacteria,1V1MJ@1239|Firmicutes,4HG4U@91061|Bacilli,3FBG0@33958|Lactobacillaceae 91061|Bacilli C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR AFLMLIMI_02771 543734.LCABL_16120 3.18e-147 414.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli,3F5K5@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2140) ypmS - - - - - - - - - - - DUF2140 AFLMLIMI_02772 543734.LCABL_16110 4.85e-196 544.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli,3F4N0@33958|Lactobacillaceae 91061|Bacilli E GDSL-like Lipase/Acylhydrolase XK27_03630 - - - - - - - - - - - Lipase_GDSL_2 AFLMLIMI_02773 543734.LCABL_16100 1.99e-189 528.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli,3F4CW@33958|Lactobacillaceae 91061|Bacilli S EDD domain protein, DegV family WQ51_01275 - - - - - - - - - - - DegV AFLMLIMI_02774 543734.LCABL_16090 1.83e-148 418.0 COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4HAT2@91061|Bacilli,3F578@33958|Lactobacillaceae 91061|Bacilli S protein, hemolysin III hlyIII - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII AFLMLIMI_02775 543734.LCABL_16080 3.64e-119 340.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli,3F6Y4@33958|Lactobacillaceae 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 AFLMLIMI_02776 543734.LCABL_16070 2.43e-243 666.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4H9QS@91061|Bacilli,3F3SB@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt AFLMLIMI_02777 543734.LCABL_16060 0.0 1209.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,3FC7W@33958|Lactobacillaceae 91061|Bacilli S ABC transporter, ATP-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn AFLMLIMI_02778 543734.LCABL_16050 2.95e-110 316.0 2A42J@1|root,30SMC@2|Bacteria,1V54W@1239|Firmicutes,4HGI5@91061|Bacilli,3F3R1@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02779 543734.LCABL_16040 3.58e-282 771.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli,3F3VH@33958|Lactobacillaceae 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 AFLMLIMI_02780 543734.LCABL_16030 8.71e-200 554.0 COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,4H9UY@91061|Bacilli,3F44R@33958|Lactobacillaceae 91061|Bacilli S Uncharacterised 5xTM membrane BCR, YitT family COG1284 ypjC - - - - - - - - - - - DUF2179,YitT_membrane AFLMLIMI_02781 543734.LCABL_16020 3.58e-301 822.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli,3F3ND@33958|Lactobacillaceae 91061|Bacilli S Tetratricopeptide repeat protein XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 AFLMLIMI_02782 1423732.BALS01000037_gene108 1.2e-54 171.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding AFLMLIMI_02783 543734.LCABL_16000 7.41e-312 850.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,3F4V0@33958|Lactobacillaceae 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 AFLMLIMI_02784 543734.LCABL_15990 1.72e-303 829.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,3F4DQ@33958|Lactobacillaceae 91061|Bacilli J Ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 AFLMLIMI_02785 543734.LCABL_15980 2.04e-149 421.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,3F3W4@33958|Lactobacillaceae 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin AFLMLIMI_02786 543734.LCABL_15970 1.68e-104 306.0 COG1388@1|root,COG1388@2|Bacteria,1VFEU@1239|Firmicutes,4HNW5@91061|Bacilli,3F6WV@33958|Lactobacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM AFLMLIMI_02787 543734.LCABL_15960 0.0 913.0 COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,4H9QP@91061|Bacilli,3F4PY@33958|Lactobacillaceae 91061|Bacilli L ATP-dependent DNA helicase RecQ recQ GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009378,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind AFLMLIMI_02788 543734.LCABL_15950 3.7e-234 644.0 COG4955@1|root,COG4955@2|Bacteria,1TQU9@1239|Firmicutes,4HJ71@91061|Bacilli,3F45N@33958|Lactobacillaceae 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_40 AFLMLIMI_02789 543734.LCABL_15940 1.16e-60 186.0 COG1141@1|root,COG1141@2|Bacteria,1VAC2@1239|Firmicutes,4HKG7@91061|Bacilli,3F7KF@33958|Lactobacillaceae 91061|Bacilli C 4Fe-4S single cluster domain of Ferredoxin I fer GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - ko:K05337 - - - - ko00000 - - - Fer4_13 AFLMLIMI_02790 543734.LCABL_15930 4.35e-123 352.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,3F4HD@33958|Lactobacillaceae 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt AFLMLIMI_02791 543734.LCABL_15920 3.15e-175 488.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,3F402@33958|Lactobacillaceae 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 AFLMLIMI_02792 543734.LCABL_15910 8.74e-139 393.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli,3F5RN@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB AFLMLIMI_02793 543734.LCABL_15900 1.07e-159 449.0 COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,3FCCZ@33958|Lactobacillaceae 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA AFLMLIMI_02794 543734.LCABL_15890 1.59e-88 259.0 COG0454@1|root,COG0456@2|Bacteria,1VAD7@1239|Firmicutes,4HKR2@91061|Bacilli,3F7QC@33958|Lactobacillaceae 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases ribT - - ko:K02859 - - - - ko00000 - - - Acetyltransf_1 AFLMLIMI_02795 543734.LCABL_15880 9.95e-211 582.0 COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae 91061|Bacilli D recombinase XerD xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase AFLMLIMI_02796 543734.LCABL_15870 1.4e-205 569.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli,3F44W@33958|Lactobacillaceae 91061|Bacilli S S1 domain yitL - - ko:K00243 - - - - ko00000 - - - S1_2 AFLMLIMI_02797 543734.LCABL_15860 4.31e-95 278.0 COG2707@1|root,COG2707@2|Bacteria,1V7JN@1239|Firmicutes,4IRT9@91061|Bacilli,3FB78@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF441) ytwI - - - - - - - - - - - DUF441 AFLMLIMI_02798 543734.LCABL_15850 0.0 1130.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli,3F3JU@33958|Lactobacillaceae 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C AFLMLIMI_02799 543734.LCABL_15840 2.21e-227 626.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli,3F4CC@33958|Lactobacillaceae 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK AFLMLIMI_02800 543734.LCABL_15830 0.0 2147.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,3F4AM@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon AFLMLIMI_02801 568703.LGG_01372 8.1e-36 121.0 2BAS8@1|root,3247E@2|Bacteria,1U6V1@1239|Firmicutes,4IGNY@91061|Bacilli,3F8J0@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF2929) - - - - - - - - - - - - DUF2929 AFLMLIMI_02802 543734.LCABL_15810 3.51e-184 516.0 2F31P@1|root,33VWT@2|Bacteria,1VWGD@1239|Firmicutes,4HWD9@91061|Bacilli,3F4CP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02803 543734.LCABL_15800 0.0 1040.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli,3FC24@33958|Lactobacillaceae 91061|Bacilli F 5'-nucleotidase, C-terminal domain ycjM - 3.1.3.5,3.1.3.6,3.1.4.16 ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02370,R02719,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos AFLMLIMI_02804 543734.LCABL_15790 5.18e-122 348.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HJXK@91061|Bacilli,3FB3S@33958|Lactobacillaceae 91061|Bacilli K Domain of unknown function (DUF1836) - - - - - - - - - - - - DUF1836 AFLMLIMI_02805 543734.LCABL_15780 1.35e-38 128.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli,3F7ZT@33958|Lactobacillaceae 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p AFLMLIMI_02806 543734.LCABL_15770 0.0 1645.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,3F3RV@33958|Lactobacillaceae 91061|Bacilli O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N AFLMLIMI_02807 543734.LCABL_15760 2.47e-65 199.0 COG5416@1|root,COG5416@2|Bacteria,1VIG5@1239|Firmicutes,4HP5V@91061|Bacilli,3F7IW@33958|Lactobacillaceae 91061|Bacilli S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom AFLMLIMI_02808 543734.LCABL_15750 1.83e-183 510.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli,3FC9J@33958|Lactobacillaceae 91061|Bacilli S Enoyl-(Acyl carrier protein) reductase yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short AFLMLIMI_02809 543734.LCABL_15740 1.1e-232 640.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli,3F4F1@33958|Lactobacillaceae 91061|Bacilli J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 AFLMLIMI_02810 543734.LCABL_15730 0.0 1285.0 COG1835@1|root,COG1835@2|Bacteria,1TPTG@1239|Firmicutes,4HB7R@91061|Bacilli,3F3WT@33958|Lactobacillaceae 91061|Bacilli I Acyltransferase oatA GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - - - - - - - - - - Acyl_transf_3 AFLMLIMI_02811 543734.LCABL_15720 3.37e-309 842.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,3F4ZA@33958|Lactobacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 AFLMLIMI_02812 543734.LCABL_15710 2.78e-170 476.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli,3F3JB@33958|Lactobacillaceae 91061|Bacilli K DeoR C terminal sensor domain fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR AFLMLIMI_02813 543734.LCABL_15700 2.76e-218 602.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli,3F3SG@33958|Lactobacillaceae 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB AFLMLIMI_02814 543734.LCABL_15690 0.0 1234.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,3F44C@33958|Lactobacillaceae 91061|Bacilli GT Phosphotransferase System fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB AFLMLIMI_02815 543734.LCABL_15670 0.0 1186.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,3F3MY@33958|Lactobacillaceae 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N AFLMLIMI_02816 543734.LCABL_15660 1.55e-171 479.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,3F3QQ@33958|Lactobacillaceae 91061|Bacilli E ABC transporter, ATP-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran AFLMLIMI_02817 543734.LCABL_15650 0.0 902.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli,3F48Y@33958|Lactobacillaceae 91061|Bacilli P ABC transporter permease glnPH2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1,SBP_bac_3 AFLMLIMI_02818 543734.LCABL_15640 3.33e-28 101.0 2AYHS@1|root,31QM8@2|Bacteria,1U8B8@1239|Firmicutes,4II98@91061|Bacilli,3FASP@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02819 543734.LCABL_15630 2.28e-63 193.0 COG1694@1|root,COG1694@2|Bacteria,1VIQA@1239|Firmicutes,4HM6C@91061|Bacilli,3F6WJ@33958|Lactobacillaceae 91061|Bacilli S mazG nucleotide pyrophosphohydrolase - - - - - - - - - - - - MazG AFLMLIMI_02820 543734.LCABL_15620 2.74e-138 391.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 AFLMLIMI_02821 543734.LCABL_15610 1.19e-296 810.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,3F41K@33958|Lactobacillaceae 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX AFLMLIMI_02822 543734.LCABL_15600 9.55e-288 790.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3F40B@33958|Lactobacillaceae 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N AFLMLIMI_02823 543734.LCABL_15590 0.0 1073.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,3F3PD@33958|Lactobacillaceae 91061|Bacilli V ABC transporter yknV - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran AFLMLIMI_02824 543734.LCABL_15580 4.73e-286 781.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,3F3ZP@33958|Lactobacillaceae 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 AFLMLIMI_02825 543734.LCABL_15570 1.93e-213 590.0 COG0457@1|root,COG0457@2|Bacteria,1W4AR@1239|Firmicutes,4HZIS@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - AFLMLIMI_02826 543734.LCABL_15560 0.0 1100.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3U9@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL AFLMLIMI_02827 1423816.BACQ01000014_gene466 2.69e-62 201.0 29Q46@1|root,30B2W@2|Bacteria,1U7FW@1239|Firmicutes,4IHBY@91061|Bacilli,3F9K7@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02828 543734.LCABL_15540 5e-57 177.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,3F7DV@33958|Lactobacillaceae 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 AFLMLIMI_02830 543734.LCABL_15530 1.44e-47 152.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli,3F7D8@33958|Lactobacillaceae 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p AFLMLIMI_02831 543734.LCABL_15520 4.17e-221 613.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,3F3TP@33958|Lactobacillaceae 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta AFLMLIMI_02832 543734.LCABL_15510 0.0 1435.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,3F3VT@33958|Lactobacillaceae 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B AFLMLIMI_02833 543734.LCABL_15500 6.74e-144 407.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,3F7NP@33958|Lactobacillaceae 91061|Bacilli L Competence protein ComEA comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB AFLMLIMI_02834 543734.LCABL_15490 1.82e-233 644.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli,3F4KY@33958|Lactobacillaceae 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 AFLMLIMI_02835 543734.LCABL_15480 4.38e-113 325.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli,3F6YS@33958|Lactobacillaceae 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like AFLMLIMI_02836 543734.LCABL_15470 5.74e-129 367.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae 91061|Bacilli L RNA methyltransferase, RsmD family rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 AFLMLIMI_02837 543734.LCABL_15460 8.46e-84 247.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli,3F70V@33958|Lactobacillaceae 91061|Bacilli S Uncharacterized protein conserved in bacteria (DUF2129) ylbG - - - - - - - - - - - DUF2129 AFLMLIMI_02838 543734.LCABL_15450 0.0 2245.0 COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,4IS56@91061|Bacilli,3F4U7@33958|Lactobacillaceae 91061|Bacilli C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second pyc - 6.4.1.1 ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 M00173 R00344 RC00040,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA AFLMLIMI_02839 543734.LCABL_15440 4.76e-269 738.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,3F4IK@33958|Lactobacillaceae 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE AFLMLIMI_02840 543734.LCABL_15430 0.0 1198.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli,3F3UK@33958|Lactobacillaceae 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 AFLMLIMI_02841 543734.LCABL_15420 3.56e-189 525.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli,3F5BB@33958|Lactobacillaceae 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P AFLMLIMI_02842 543734.LCABL_15410 6.15e-62 189.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli,3F80A@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 AFLMLIMI_02843 543734.LCABL_15400 4.32e-202 560.0 COG0039@1|root,COG0039@2|Bacteria,1UFQZ@1239|Firmicutes,4IEWQ@91061|Bacilli,3F4RQ@33958|Lactobacillaceae 91061|Bacilli C L-malate dehydrogenase activity - - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - - AFLMLIMI_02844 543734.LCABL_15390 0.0 896.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HB3K@91061|Bacilli,3F426@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase pdhD - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim AFLMLIMI_02845 543734.LCABL_15380 0.0 988.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,3F3RR@33958|Lactobacillaceae 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex pdhC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding AFLMLIMI_02846 543734.LCABL_15370 1.15e-232 640.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HA4H@91061|Bacilli,3F4RV@33958|Lactobacillaceae 91061|Bacilli C Transketolase, C-terminal domain protein pdhB - 1.2.4.1 ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14590 Transket_pyr,Transketolase_C AFLMLIMI_02847 543734.LCABL_15360 1.42e-267 732.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4H9PQ@91061|Bacilli,3F3JK@33958|Lactobacillaceae 91061|Bacilli C Dehydrogenase E1 component pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh AFLMLIMI_02848 1423816.BACQ01000014_gene486 5.13e-112 330.0 29Q2F@1|root,30B13@2|Bacteria,1U7D2@1239|Firmicutes,4IH8M@91061|Bacilli,3F9EB@33958|Lactobacillaceae 91061|Bacilli S E1-E2 ATPase - - - - - - - - - - - - E1-E2_ATPase AFLMLIMI_02849 543734.LCABL_15330 2.79e-131 372.0 COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,4HH0G@91061|Bacilli,3F3YH@33958|Lactobacillaceae 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase AFLMLIMI_02850 543734.LCABL_15320 1e-62 192.0 29QQZ@1|root,30BQS@2|Bacteria,1U8HD@1239|Firmicutes,4IIF9@91061|Bacilli,3FAZK@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02851 543734.LCABL_15310 6.45e-95 277.0 2C389@1|root,2ZQCN@2|Bacteria,1VQPI@1239|Firmicutes,4I0G9@91061|Bacilli,3F79N@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02852 543734.LCABL_15300 2.02e-43 141.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli,3F807@33958|Lactobacillaceae 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 AFLMLIMI_02853 543734.LCABL_15290 0.0 1105.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,3F3TT@33958|Lactobacillaceae 91061|Bacilli J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL AFLMLIMI_02854 1423816.BACQ01000066_gene2543 1.79e-67 227.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli,3F4S3@33958|Lactobacillaceae 91061|Bacilli U TraM recognition site of TraD and TraG - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf AFLMLIMI_02855 543734.LCABL_05910 6.21e-27 108.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli,3F4S3@33958|Lactobacillaceae 91061|Bacilli U TraM recognition site of TraD and TraG - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf AFLMLIMI_02856 543734.LCABL_05920 4.24e-200 572.0 COG3266@1|root,COG3266@2|Bacteria,1TSNJ@1239|Firmicutes,4HEFK@91061|Bacilli 91061|Bacilli S domain, Protein - - - - - - - - - - - - - AFLMLIMI_02857 543734.LCABL_05920 8.17e-81 265.0 COG3266@1|root,COG3266@2|Bacteria,1TSNJ@1239|Firmicutes,4HEFK@91061|Bacilli 91061|Bacilli S domain, Protein - - - - - - - - - - - - - AFLMLIMI_02859 1423732.BALS01000054_gene2749 4.68e-21 88.6 2DME1@1|root,32QVI@2|Bacteria,1V94J@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - AFLMLIMI_02860 543734.LCABL_05950 4.68e-45 160.0 COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes,4HA4T@91061|Bacilli,3F6HE@33958|Lactobacillaceae 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87 AFLMLIMI_02861 1423816.BACQ01000066_gene2547 2.37e-48 169.0 COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes,4HA4T@91061|Bacilli,3F6HE@33958|Lactobacillaceae 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87 AFLMLIMI_02862 1423816.BACQ01000066_gene2547 9.8e-124 369.0 COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes,4HA4T@91061|Bacilli,3F6HE@33958|Lactobacillaceae 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87 AFLMLIMI_02863 1423816.BACQ01000066_gene2547 1.37e-196 560.0 COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes,4HA4T@91061|Bacilli,3F6HE@33958|Lactobacillaceae 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87 AFLMLIMI_02864 543734.LCABL_05960 8.1e-158 447.0 COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria 2|Bacteria M cysteine-type peptidase activity - - - ko:K21471,ko:K21472 - - - - ko00000,ko01000,ko01002,ko01011 - - - NLPC_P60,Peptidase_M23 AFLMLIMI_02869 1158614.I592_04174 0.000569 42.7 2DK2G@1|root,3088P@2|Bacteria,1U30M@1239|Firmicutes,4ICQK@91061|Bacilli,4B5DJ@81852|Enterococcaceae 91061|Bacilli S Ribbon-helix-helix protein, copG family - - - - - - - - - - - - RHH_1 AFLMLIMI_02871 1423732.BALS01000076_gene2137 7.86e-285 780.0 COG0790@1|root,COG0790@2|Bacteria,1UHSY@1239|Firmicutes,4IS8P@91061|Bacilli,3F8F0@33958|Lactobacillaceae 91061|Bacilli S COG0790 FOG TPR repeat, SEL1 subfamily - - - - - - - - - - - - - AFLMLIMI_02873 543734.LCABL_06050 0.0 1627.0 COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HKTX@91061|Bacilli,3F8MI@33958|Lactobacillaceae 91061|Bacilli L Protein of unknown function (DUF3991) - - - - - - - - - - - - DUF3991,Toprim_2 AFLMLIMI_02874 641146.HMPREF9020_01162 2.49e-87 256.0 2ED72@1|root,3373P@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - AFLMLIMI_02875 1423816.BACQ01000066_gene2559 1.42e-22 87.0 293FZ@1|root,2ZQYB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - AFLMLIMI_02876 1423732.BALS01000076_gene2132 1.65e-97 284.0 2DUJT@1|root,33R01@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - AFLMLIMI_02877 543734.LCABL_06130 3.33e-92 270.0 2F273@1|root,33V59@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - AFLMLIMI_02878 1302286.BAOT01000083_gene2225 2.57e-96 299.0 COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,4HDAB@91061|Bacilli,3F40X@33958|Lactobacillaceae 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 AFLMLIMI_02880 278197.PEPE_0498 2.22e-206 572.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HTRR@91061|Bacilli,3F3WY@33958|Lactobacillaceae 91061|Bacilli L Transposase and inactivated derivatives, IS30 family - - - - - - - - - - - - - AFLMLIMI_02881 543734.LCABL_06160 3.38e-149 421.0 COG3764@1|root,COG3764@2|Bacteria,1V4ZG@1239|Firmicutes,4HMUE@91061|Bacilli,3FBG7@33958|Lactobacillaceae 91061|Bacilli M Sortase family srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase AFLMLIMI_02884 314315.LCA_0763 6.24e-79 251.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli,3F3PB@33958|Lactobacillaceae 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 AFLMLIMI_02885 568703.LGG_00649 1.01e-278 777.0 COG1440@1|root,COG1455@1|root,COG1440@2|Bacteria,COG1455@2|Bacteria,1TQPV@1239|Firmicutes,4HC9I@91061|Bacilli,3F4DV@33958|Lactobacillaceae 91061|Bacilli G Phosphotransferase system, EIIC lacE GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016310,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0071704 2.7.1.207 ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 M00281 R04393 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1 - - PTS_EIIC,PTS_IIB AFLMLIMI_02886 543734.LCABL_07280 4.36e-228 641.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,3FC7B@33958|Lactobacillaceae 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family lacG GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657 3.2.1.21,3.2.1.85,3.2.1.86 ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 - R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 AFLMLIMI_02887 1423732.BALS01000046_gene2613 2.48e-45 149.0 COG1447@1|root,COG1447@2|Bacteria,1V87W@1239|Firmicutes,4HJSY@91061|Bacilli,3FCDI@33958|Lactobacillaceae 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIA subunit lacF - 2.7.1.196,2.7.1.205,2.7.1.207 ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 M00275,M00281 R04393,R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.1,4.A.3.2 - - PTS_IIA AFLMLIMI_02888 706437.HMPREF0813_01946 2.09e-225 650.0 COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,4HBYA@91061|Bacilli,42EAB@671232|Streptococcus anginosus group 91061|Bacilli M Glycosyl hydrolase family 53 ganB - 3.2.1.89 ko:K01224 - - - - ko00000,ko01000 - - - Big_4,Glyco_hydro_53,SLH AFLMLIMI_02890 1423732.BALS01000052_gene2788 1.51e-19 79.3 29QPW@1|root,30BPK@2|Bacteria,1U8F6@1239|Firmicutes,4IID2@91061|Bacilli,3FAX1@33958|Lactobacillaceae 91061|Bacilli S YvrJ protein family - - - - - - - - - - - - YvrJ AFLMLIMI_02891 1423780.LOT_2232 7.79e-115 330.0 2DPIQ@1|root,3328X@2|Bacteria,1VFYC@1239|Firmicutes,4HNHQ@91061|Bacilli,3F7RW@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - AP2 AFLMLIMI_02892 568703.LGG_00437 7.46e-59 182.0 COG0272@1|root,COG0272@2|Bacteria,1W4JC@1239|Firmicutes,4I09W@91061|Bacilli,3F83P@33958|Lactobacillaceae 91061|Bacilli L BRCA1 C Terminus (BRCT) domain - - - - - - - - - - - - BRCT AFLMLIMI_02893 1291743.LOSG293_590050 2.81e-149 420.0 COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,4IQ61@91061|Bacilli,3FBG4@33958|Lactobacillaceae 91061|Bacilli L Resolvase, N terminal domain - - - - - - - - - - - - Resolvase AFLMLIMI_02894 1291743.LOSG293_090370 1.4e-121 351.0 COG0518@1|root,COG0518@2|Bacteria,1UAH0@1239|Firmicutes,4HHTX@91061|Bacilli,3F4AV@33958|Lactobacillaceae 91061|Bacilli F glutamine amidotransferase - - - - - - - - - - - - GATase AFLMLIMI_02895 543734.LCABL_06580 1.31e-81 241.0 28ZBI@1|root,2ZM3D@2|Bacteria,1W5K5@1239|Firmicutes,4I1Q6@91061|Bacilli,3F825@33958|Lactobacillaceae 91061|Bacilli S Protein of unknown function (DUF1093) - - - - - - - - - - - - DUF1093 AFLMLIMI_02896 762051.LKI_00815 9.67e-103 317.0 COG2211@1|root,COG2211@2|Bacteria,1TR4D@1239|Firmicutes,4HDCY@91061|Bacilli 91061|Bacilli G Permeases of the major facilitator superfamily yjbB - - - - - - - - - - - MFS_1,MFS_3 AFLMLIMI_02897 1423732.BALS01000152_gene507 1.29e-208 580.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_02898 543734.LCABL_21290 2.46e-67 210.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HDNZ@91061|Bacilli,3F4RD@33958|Lactobacillaceae 91061|Bacilli L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein tnpA1 - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 AFLMLIMI_02899 1423732.BALS01000125_gene2500 6.38e-64 194.0 COG3041@1|root,COG3041@2|Bacteria,1VP6F@1239|Firmicutes,4IG7D@91061|Bacilli,3F7SV@33958|Lactobacillaceae 91061|Bacilli S Bacterial toxin of type II toxin-antitoxin system, YafQ - - - - - - - - - - - - YafQ_toxin AFLMLIMI_02900 1133569.AHYZ01000163_gene283 4.96e-44 143.0 COG3077@1|root,COG3077@2|Bacteria,1U6X0@1239|Firmicutes,4IGR7@91061|Bacilli,3F8N7@33958|Lactobacillaceae 91061|Bacilli L RelB antitoxin - - - - - - - - - - - - RelB AFLMLIMI_02902 543734.LCABL_02920 2.29e-107 310.0 COG3444@1|root,COG3444@2|Bacteria,1V46G@1239|Firmicutes,4HHPN@91061|Bacilli,3FC7S@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose subfamily IIB component - - 2.7.1.191 ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - PTSIIB_sorb AFLMLIMI_02903 543734.LCABL_02930 2.7e-205 569.0 COG3715@1|root,COG3715@2|Bacteria,1TSX0@1239|Firmicutes,4HBRB@91061|Bacilli,3F4X4@33958|Lactobacillaceae 91061|Bacilli G PTS system sorbose-specific iic component - - - ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EII-Sor AFLMLIMI_02904 543734.LCABL_02940 2.12e-186 519.0 COG3716@1|root,COG3716@2|Bacteria,1UMKU@1239|Firmicutes,4HC75@91061|Bacilli,3F434@33958|Lactobacillaceae 91061|Bacilli G PTS system mannose/fructose/sorbose family IID component - - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA AFLMLIMI_02905 568703.LGG_00434 0.0 1078.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,3F4B7@33958|Lactobacillaceae 91061|Bacilli G Glycosyl hydrolase family 3 N terminal domain nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - DUF4309,Glyco_hydro_3 AFLMLIMI_02906 543734.LCABL_21480 2.14e-163 457.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,3F4NE@33958|Lactobacillaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 AFLMLIMI_02907 543734.LCABL_05810 7.37e-53 174.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,4HD6M@91061|Bacilli,3F43M@33958|Lactobacillaceae 91061|Bacilli L hmm pf00665 - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve AFLMLIMI_02908 387344.LVIS_0444 3.65e-133 389.0 COG1609@1|root,COG1609@2|Bacteria,1VSEE@1239|Firmicutes,4HTEF@91061|Bacilli,3FC5F@33958|Lactobacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor kdgR - - ko:K02525 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_4 AFLMLIMI_02909 1071400.LBUCD034_0079 6.69e-100 295.0 COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,3F6AY@33958|Lactobacillaceae 91061|Bacilli G KDPG and KHG aldolase eda - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase AFLMLIMI_02910 525318.HMPREF0497_1068 7.92e-95 280.0 COG0794@1|root,COG0794@2|Bacteria,1V3UJ@1239|Firmicutes,4HH5G@91061|Bacilli,3F7I2@33958|Lactobacillaceae 91061|Bacilli M sugar phosphate isomerase involved in capsule formation hxlB - 5.3.1.27 ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05339,R09780 RC00377 ko00000,ko00001,ko00002,ko01000 - - - SIS AFLMLIMI_02911 1071400.LBUCD034_0077 8.29e-80 244.0 COG0269@1|root,COG0269@2|Bacteria,1V5A2@1239|Firmicutes,4IQTQ@91061|Bacilli,3FBIZ@33958|Lactobacillaceae 91061|Bacilli G Orotidine 5'-phosphate decarboxylase / HUMPS family hxlA - 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase AFLMLIMI_02912 1291743.LOSG293_410100 9.99e-172 486.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,4HBH6@91061|Bacilli,3F4FT@33958|Lactobacillaceae 91061|Bacilli G pfkB family carbohydrate kinase kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB AFLMLIMI_02913 1071400.LBUCD034_0075 2.31e-232 648.0 COG2610@1|root,COG2610@2|Bacteria,1UIHX@1239|Firmicutes,4ISSR@91061|Bacilli,3F4AP@33958|Lactobacillaceae 91061|Bacilli EG Citrate transporter gntT - - - - - - - - - - - - AFLMLIMI_02914 1071400.LBUCD034_0074 2.17e-135 388.0 COG1082@1|root,COG1082@2|Bacteria,1V82S@1239|Firmicutes,4IRUU@91061|Bacilli,3FBQ6@33958|Lactobacillaceae 91061|Bacilli G Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2 AFLMLIMI_02916 543734.LCABL_21480 1.24e-162 455.0 COG3316@1|root,COG3316@2|Bacteria,1TTKR@1239|Firmicutes,4HCB4@91061|Bacilli,3F4NE@33958|Lactobacillaceae 91061|Bacilli L DDE domain tnp1216 - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 AFLMLIMI_02917 543734.LCABL_13980 1.4e-21 91.7 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli,3F3WP@33958|Lactobacillaceae 91061|Bacilli P Belongs to the nlpA lipoprotein family - - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 AFLMLIMI_02918 1122147.AUEH01000077_gene20 1.4e-126 376.0 COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,3F3N9@33958|Lactobacillaceae 91061|Bacilli E succinyl-diaminopimelate desuccinylase - - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 AFLMLIMI_02920 1423755.BAML01000037_gene1522 7.53e-106 315.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HCBZ@91061|Bacilli,3F4QA@33958|Lactobacillaceae 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein soj - - - - - - - - - - - AAA_31 AFLMLIMI_02921 944562.HMPREF9102_2161 4.69e-105 320.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,3F55E@33958|Lactobacillaceae 91061|Bacilli S Replication initiator protein A repA - - - - - - - - - - - RepA_N AFLMLIMI_02928 1423816.BACQ01000047_gene1785 2.89e-187 536.0 COG4990@1|root,COG4990@2|Bacteria,1VE2G@1239|Firmicutes,4HMDI@91061|Bacilli,3F6FB@33958|Lactobacillaceae 91061|Bacilli M Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 AFLMLIMI_02930 1260356.D920_01135 1.73e-91 287.0 COG3757@1|root,COG4990@1|root,COG3757@2|Bacteria,COG4990@2|Bacteria,1VE2G@1239|Firmicutes,4HMDI@91061|Bacilli,4B0WD@81852|Enterococcaceae 91061|Bacilli M Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 AFLMLIMI_02932 1235792.C808_01203 2.07e-27 125.0 COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,27IY7@186928|unclassified Lachnospiraceae 186801|Clostridia M Psort location Cellwall, score - - - - - - - - - - - - Peptidase_S8 AFLMLIMI_02939 1423732.BALS01000054_gene2738 2.28e-40 134.0 2C3WB@1|root,33NQV@2|Bacteria,1VQ12@1239|Firmicutes,4HSYA@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02940 543734.LCABL_05870 3.15e-263 725.0 2EG0H@1|root,339SH@2|Bacteria,1VP01@1239|Firmicutes,4HS1I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - AFLMLIMI_02941 1423816.BACQ01000066_gene2540 1.83e-284 788.0 COG4932@1|root,COG4932@2|Bacteria,1V9ZD@1239|Firmicutes,4ITN8@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF5011) - - - - - - - - - - - - DUF5011 ## 2636 queries scanned ## Total time (seconds): 2.6640665531158447 ## Rate: 989.46 q/s