LOCUS       gnlProkkaDGIOIDPF_23   24054 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DGIOIDPF_23.
ACCESSION   gnlProkkaDGIOIDPF_23
VERSION     gnlProkkaDGIOIDPF_23
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 12:17:57
            Original ID  :: gnl|Prokka|DGIOIDPF_23
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 22741
            Orig. end    :: 46795
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24054
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:14054]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14054
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..24054
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24054
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             821..2164
                     /locus_tag="ctg23_24"
                     /transl_table=11
                     /translation="MIKIYDTMTRSLRDFVPLTENTVNMYVCGPTVYNYIHIGNARSTV
                     AFDTIRRYFEYRGYTVNYISNFTDVDDKIIKAANEVGISTKELSDKFITAFMEDTAQLG
                     IKPATQNPRVINYMDEIIAFVSILIDKGFAYVSEGDVYFRVTKSNNYAKLANKTLEDLE
                     IGASGRTDAETDRKEDPLDFALWKAAKEGEISWESPWGPGRPGWHIECSVMATEILGDT
                     IDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVNVDNEKMSKSLGNFVTVHD
                     MLKTVDGQVLRFFLATQQYRKPINFTEKAIHDAEVNLKYLKNTHSLPLTEEVSQAELQA
                     YLDAFQAAMDDDFNTANGVTVLFDMAKWINSGNYDETVKNAFEKILQVFGIVFEEETLD
                     EDIEKLIEERQAARANKDFATADRIRDELAAQGIKLLDTKEGVRWTRD"
     CDS             2157..2558
                     /locus_tag="ctg23_25"
                     /transl_table=11
                     /translation="MTKHIDVNLINGIALAFEGDAVYSLYIRRHLIFQGQTKPNQLHRL
                     ATRYVSAKAQASLIEKMLERELLTEKELDIYKRGRNAKSHTKAKNTDVITYKMSTGFEA
                     VMGYLHMTEDIDRLEELVAWCIDEVEKEI"
     CDS             2840..2995
                     /locus_tag="ctg23_26"
                     /transl_table=11
                     /translation="MNEIAKEKVFYTTFVVLILSSFMLQTGKADEVQVKSDEAKIDYVN
                     SEASAP"
     CDS             3071..3259
                     /locus_tag="ctg23_27"
                     /transl_table=11
                     /translation="MVFSSCETDEALLEVHSQVDIVETSVSMAKPHSEEARVQALGEDR
                     SVAGSERGDSSPISEVA"
     CDS             3330..3572
                     /locus_tag="ctg23_28"
                     /transl_table=11
                     /translation="MIYSSEVTFTDELISEISGNSSTSAGSIDILQAAGKTVTQAARKI
                     AESIADLDTIGKQTLAAARVVLFLLVLYLAEITFI"
     CDS             3620..4363
                     /locus_tag="ctg23_29"
                     /transl_table=11
                     /translation="MKTTKESILDIVYGVHAVTESLEANTGNKLYIQDDLRGKNVDAIK
                     ALAAEKKVSISWTPKKTLSDMTGGAVHQGFVLRVSEFAYSDLSVIMDKAEQEENPLILI
                     LDGLNDPHNFGSILRTADATQVTGVIIPKHRAVGVTPVVAKTSTGAVEHIPIARVTNLS
                     QTLDKLKEAGFWVFGTDMDGTASHKWNTAGKLALIIGNEGKGISANIKKQVDEMITIPM
                     GGHVQSLNASVAAAVLMYEVYRNRL"
     CDS             4366..4881
                     /locus_tag="ctg23_30"
                     /transl_table=11
                     /translation="MKKRILLVDGYNMIAFWKETRQLFKINQLDEARETLLRKLNHYAN
                     FEHIDIICVFDAQFVPGNRQRYDQYRVSVIFTEEDETADSYIERSAAEMNTIQNLVEVA
                     TSDLNEQWGIFSQGALRVSARELEERVNTVKSDLDKMSAHIDLTTPKLRPWDETQLGKL
                     QNLLNEIK"
     CDS             4890..5750
                     /locus_tag="ctg23_31"
                     /transl_table=11
                     /translation="MTFKILTDSTADLDERWAQENDVELIGLTITLDDITYETVGPNRL
                     TSDRLLEAMKEGGQPTTSQVNVGQFEEVFRRHAQNGDDLLYLAFSSVLSGTYQSAVMAR
                     DMILDEHPEAVIEIVDTLAAAGGEGYLSILAAEARDQGKSLAKTKAMIEDILPRLRTYF
                     LVDDLYHLMRGGRLSKSSAIIGSLINIKPLLWLDDSGKLVPLAKIRGRKKAIKEMVLYA
                     TQDIGHSTAIVAYANDLEAAENLKEQLLTVNGIEQVLIMPLGPVISTHVGPGTLAIFTI
                     GEKAR"
     CDS             5864..5959
                     /locus_tag="ctg23_32"
                     /transl_table=11
                     /translation="MFQNEKGDNVLVTSVAKGEFYNEYQRIKKKE"
     CDS             5928..6020
                     /locus_tag="ctg23_33"
                     /transl_table=11
                     /translation="MNINELRKKNNLSQDGFANLFHVSRQTVSS"
     CDS             6051..6551
                     /locus_tag="ctg23_34"
                     /transl_table=11
                     /translation="MLIKISQHFGISVDDLVKNEMQLTTNNKSKTNSRLWLIALPIFVL
                     ICVIAVGRNKHNSQSVNFSMKDDKTYKSNDAAQTSLTVAKGYFTVPKAGKLEVKVNATT
                     DNGNLHLTIVDNNHHHYYQIDGDDLKDSQKLYFKSGDYCIRITADAYTEKVVSLDYNIK
                     VNS"
     CDS             6699..7655
                     /locus_tag="ctg23_35"
                     /transl_table=11
                     /translation="MALTYAVLGSGAMGLRFGLLLKEHLGAQVDFIDTWEEQIDTVRKQ
                     GGVYQSRDGKNRHLIPISIQTPEEYQGKPDVFIIFDKQMHLSQLLERSKHFFHENQYVF
                     TGMNGMGHIEKINRYFVPEKVLAGTCLIGTVLKDAGDVDFIGKAGAGSINIAAQSGTVD
                     DVQKQIITEFEASNLNPNLTDNFLGTLYTKVVFNSVINTICTLFEIRMGQFIDYEGAEK
                     LGRQLIDEAYNVAELAGITPLNSRDEEWETIRYVSAETSPLHYPSMYQDMNKGRQTEVD
                     YINGYIYDLGRTYNYQAKTHDFLRHLVHLAENTRKFR"
     CDS             7864..8310
                     /locus_tag="ctg23_36"
                     /transl_table=11
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKPT
                     FTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSMYPGGLKQISAGELRSKNAVRLIE
                     KSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     CDS             8338..8730
                     /locus_tag="ctg23_37"
                     /transl_table=11
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDLEEYIPHADLR
                     LVINQPFAVTSTEGSYDVHVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAGLL
                     TRDARMVERKKPGLKKARKASQFSKR"
     CDS             9244..9468
                     /locus_tag="ctg23_38"
                     /transl_table=11
                     /translation="MEPKYHNGSVALIRETGFDYDGAVYAVVCNSQTYIKRVYLEAEGL
                     RLKYKDIFISYDEDPRVVRIIIGNFIPLK"
     CDS             9718..9822
                     /locus_tag="ctg23_39"
                     /transl_table=11
                     /translation="MENTEFSLELDVTEVSTEQGYVSGGVTSTGCCKD"
     CDS             10001..10279
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_40"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.3e-14, bitscore:
                     45.2, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVANPQFFHNLTKEKIYKNSTFRNYVKRSITRATPFGLFSSIG
                     VGTFSDISYHQKIGENYTKKISVSGEWLSSICMMLENKDSVLLQLHI"
     CDS             10430..12793
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     577; E-value: 1.1e-174)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_41"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-64, bitscore:
                     210.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.9e-18, bitscore:
                     59.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELVLQSKSPDLEKQKILDYIRNLITNEFLFTNLRKVAISHKDL
                     DDLTNILKDINNQRKLTEDLLQIKNSIEQYAKLELGEGISQYTEICKKMSYIFNDKKQH
                     YLKVDLVNCCDSVLPKNLKKKMEDFVNFISKINLAKGYRNRELESFTEKFVEKYGEYVE
                     VPIKELLDGNLGLGLPKQTLGTHVKSSSSVEEQNFLSYLSKEVFKAVKNCKKEIDISNI
                     PLGLLYPNSDRFVANQLELYCEIKNFESQPVISVVPNTGSDMIGKSIGRFASYFPNSYI
                     SLDSQLDNVELIEFPRDSKNLNVMSAQNAHSKKLLLSYDDNDNTSIELDSVVVGVIKTE
                     YRYKLYFRDLRTGSIVNFVTTSMLNHKSNGVFSDLARFLLAVSLEWQDNPFSVFRIIEN
                     FDYLPYIPKIKYGNIILSEEKWVLSDIDKNDLSSIKQWKKDFDVPRLLYFHKADERLLV
                     DLENDLDTQWLLKQNVDKLYFTRFEKYDGKNCEFIFGFENYQSSINHYSMQEKSVRRLT
                     NNFYKNYVKTFSSDWIYFRLYGINSSILLELRERLLLFTDELLVEKLISDFHFVNYSDK
                     DNGSLRLRFKINNDDNFEDLRFRIAHWIDFLLESGFCNDVSFNLYEREIERYGGDNFIT
                     VCERMFSIDSFLTLKLFSKKLLNDKDLFSVLHSTFLYIRLLGIPLKRLLELLKGNLTQN
                     RYRKSFKKLFPNNTIVVKEFKEYFDYKNQFEIFNEVFREFPPIDGYFEGKNDIVYSLLH
                     MHMNRVGMFPYREKEYLYFIMYIAEPLNNYKEFT"
     CDS             12831..14054
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     308.8; E-value: 9.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_42"
                     /sec_met_domain="LANC_like (E-value: 6.6e-52, bitscore:
                     168.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSDIIDRLQRAYYTENRSYLSEYPSIIIYLSYRLINCDNKEYS
                     KLLYNRVNYYLQELLKSIKLNSTNNISLCYGFTGYVYALEFLSKNCKGYDKLLDTLETI
                     LLALTKDRLREIKSSNIVKEEYFDVIQGVSSVARYLLSKEESTSEQELLVKEILNYFAD
                     LIINEPTIYVEYMPNEKLRKRFPSGYINLGVAHGILGPLYVLALGFEKFNITKHIPSIE
                     KGLSYYENAFFTNTIGKIIGWNGRVSDYEENEEFRFNISWCYGSLGMARVLYNIAKIID
                     SQKLREMAMDVFTSSIDYLNSSEILNNGICHGRSGIMLLFNLMYLDTGKTQFKAISDNL
                     FKEIINDASNSEYIFVERDIYFRGVTFDEVIDYIDFGLLNGVSGIVITLMAQRTGNAYP
                     LDRMLFMQ"
     CDS             14078..15343
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 93.7; E-value: 1.9e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_43"
                     /transl_table=11
                     /translation="MRKILKNKLYLKVLVSDLISNFGDTLYFIALMTYVTEIKESNLAI
                     SIVNISETLPILFTIFFGIIADKTLNKVKMIIKTLWLRVILYLLVAVAMNFKPSIIVVI
                     IASLINLVADTLGQFENGLFYPISNRIVKKSDREETMAFRQTVVSTMNIVNQSLGAFLI
                     TFFSFSHLAFINSLTFAISLLIMLAIRNQINSYYDETISTSKISQFDFKASFSEIISNL
                     KLSINHLFSIGNMKEALLVIPILNGSLAILIPLVVVNLSKDSNLTIVNSAITISLLGIS
                     TVSGGILGGTLILISKKFKSLSIGTLLKMNLTIVLLSFVAFYFQNIYLIILSSFLSSVL
                     VSALNPKMGTIIFNNIDETKLATIFGGMVTYFQIGDIVSRLLFSTLVIYLPYGYIALIY
                     IAVVFVAILYTLKSSNHIEREF"
     CDS             15353..15520
                     /locus_tag="ctg23_44"
                     /transl_table=11
                     /translation="MIIVFQIFYYENLFSRLSTKVRDFVRTQLREFQYLDDGQFKTLPE
                     YPEFAWFEGM"
     CDS             15571..16083
                     /locus_tag="ctg23_45"
                     /transl_table=11
                     /translation="MMFDDRLEIYSPGKLPNIVTVENIKHERFSRNPRIARTLTEFGWV
                     REMNEGVKRIYSEMESYFLHEPKYTEPGNKVVLTLENNILSRHLRVNDKMMKKYDEFND
                     LNDDEKAILHIMYNTGEKMTTALAARITNRGRNFASKLLKSLVNKEILEWHGTSKQDRN
                     QYYTLAE"
     CDS             complement(16420..17637)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 111.7; E-value: 9.5e-34)"
                     /gene_kind="other"
                     /locus_tag="ctg23_46"
                     /transl_table=11
                     /translation="MSIKKTKDGTYQLRLYIPEDVQAKLGLGKLFERKYKTRREAKEVE
                     LKLSIDIKNAKSGKSHINIKNKGEIIFKKFYEDIWLEPYKAGQTTTTIKPPTKATVFQT
                     ENIFRLHILPILGKYSIEYPNNNKQLILSLLTPKANSYANFKVIRSHVNSVFDWAEELE
                     YIPSNKLRKTITRIKANKKILLKESKREEDLSLDKEELKLWLQAFDIDLEKGLIDLKDY
                     TLFYTTFFLSDRKSESYALQWKHINFSTGETLIEQALDRFGNIKPTKGRKKTLFKTPIE
                     LIELLANWKARQQEELKLFGLRQTQKQFVFTYNDRSNNINLPLHVDYLNYRMKSVRRRH
                     PELAPASPHKLRHAGVTLAKQAGYSLEAISEALTHSDKQITKTYVNTKDIVNRTVGDIA
                     FRSLKK"
     CDS             complement(17648..17920)
                     /locus_tag="ctg23_47"
                     /transl_table=11
                     /translation="MLVQLPEEQTQEIQQMIATLIKNEIHHFKEDIGADSTFLNKKQTY
                     NYLGISNNTLDIGIAMGLPYIRIGKSISFNKKSINQWMTRLEISA"
     CDS             complement(17982..19172)
                     /locus_tag="ctg23_48"
                     /transl_table=11
                     /translation="MIKESFPFDILNLFDTKGTPPFNFSNQYLNPNTKILDFNNATLYE
                     VDFDSLSPDTKAKLQEGAYKIGESRKVEGNLRAVIVDTTDQKNRVEDLTLRKMTNNNEN
                     QVPSDLIAQAQLKQIYNLLLDIKENQDYQIRWERNNSILAPFYSARTKVIEANNSKDFR
                     EKVKSLKDANTLFEESVSAIKSDIISNRDEIIKKISQPTYRQASLQTHADFLLQDIEIM
                     TKIVGMQIYIDLTLNNEGIAHDRLLSFQGSMELVSKQNIPYKTNYLKELAKKLLYVKEL
                     KWIKNNSIPKVSLLELIHNHYSYSKNNRDLFININTKLIEFHQDSNVNLSNTETAKIET
                     EKKMTLKTKKCKTCKKTISSPKTIPICDACRNKGKQLTVVGVALLVFFNKIINKKN"
     CDS             complement(19419..19676)
                     /locus_tag="ctg23_49"
                     /transl_table=11
                     /translation="MGNGGQWINAPGYQTTHTPTEHSALSFSPGQAGADPTYGHIAFVE
                     QVKSDGSILISESNIKGLGVVSYRTFDAETAKQITYVIGH"
     CDS             complement(19652..20017)
                     /locus_tag="ctg23_50"
                     /transl_table=11
                     /translation="MTKRKNLRVVLSTRQQMVASTSPIPLALGKGVLKPCKNSIPISMS
                     MEVHQKPLNRRKEKTETEAVSQQGMSHKAISSPKKSIPQATQDCLILGDNVPGLSITEE
                     KKSVLASESIWEMVANG"
     CDS             complement(20184..20870)
                     /locus_tag="ctg23_51"
                     /transl_table=11
                     /translation="MTINHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKY
                     LNNLIEQDHRPVKRRNKFYRSLRIASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKV
                     LLGIPA"
     CDS             21020..22237
                     /locus_tag="ctg23_52"
                     /transl_table=11
                     /translation="MKQSQAKKHDNTMTNKILMRLIALVLGLLFLEILIIHSKNEQQKS
                     VSNQVQTARIMANGDLLYHDGLYMSALQADGSYDFTENFTYVKPWLKQADLVLGDFEGT
                     INPDYPLSGYPLFNAPQSVTAAISDAGYDVMDLAHNHILDSGLEGAFTTADAFKEVGID
                     PVGVYENPVRDKAPLFIKNVNGIKVAILSYAYGFNGLESNLTEKEIANHLSNLDEKRMK
                     VEIERAEKEADVTVIMPQMGVEYRLEPTDEQVKLYHKMIDWGADIIFGGHPHVVEPSEV
                     VKKDGQQKLIIYSMGNFISNQRIETMDGVDSAAWTERGVLMDVTLEKKNCQTTIKTAQA
                     HPTWVNRTPKGTISPEGYPLYTYQTYILEDFIKGGKYRNKLDEETKERIDTAYKEMNAH
                     VNLKWK"
     CDS             22558..22824
                     /locus_tag="ctg23_53"
                     /transl_table=11
                     /translation="MKAIITVVGKDKAGIVAGVATKIAELGLNIDDITQTILDEFFTMM
                     AVVSSEDKKDFTHLRAELEAFGESLNVKINIQSSAIFDAMHNL"
ORIGIN
        1 ttggactcag attgagattc accctggggc tcagattgct gaaggtgtct ttattgatca
       61 cggttctggc cttgtcattg gtgaaacagc tgtggttgaa aaaggagcta tgctctatca
      121 cggtgttact ttaggtggta ctggtaaaga tgtcggaaaa cgtcacccaa ccgttcgtga
      181 gggtgcattg gtttcagccc atgctcagat tattggccct attgagattg gaaaaaatgc
      241 caaggtaggt gcaggagctg tggttgttgc cgatgtccca gaagatgtta cggtagttgg
      301 tgtccctgct aaggtcgtac gtgttcacgg taaaaaggat gaagaagtga ttcatgacat
      361 tgaggaaggt cgtgaatact atagcgaaaa gctagaagat cttctaaaag cagctagctt
      421 tcactcatca cgtctataag gaaagaaaaa gatgagactc tttagttcaa aggtgactcg
      481 actgaccgtt gtaggtccac tcgctcttgt ttacattgct ttacatagag gggattatag
      541 caggactgct ttatggtttt gtatctcttt tttgtgggct ggtattgtct acaagcaacg
      601 tcacaagtga gacttgagtt gtgaaaaaat tgttcaaaag taatcctttt ttggtctttt
      661 attttatata gttgggagct ttgtttctgc tttgtttctt ttggctcaag gtctgctagt
      721 tgcggccatg gggattatca ttctcgttat actcttatgt ttatacttaa accattttag
      781 ggataaaaaa tagtctccaa ttaattgaaa ggaatctcta gtgataaaaa tttatgatac
      841 aatgacacgt tcgctccgtg atttcgtacc tttgacagag aacactgtca atatgtatgt
      901 ttgcggacca accgtctaca attatattca tatcggaaat gcccgttcaa cagtagcttt
      961 tgataccatt cgtcgttatt ttgagtatcg tggttacact gttaactaca tttctaactt
     1021 tacagatgta gatgataaga ttatcaaggc ggccaatgaa gttggtattt cgaccaaaga
     1081 attatcagac aagtttatca cagcctttat ggaagatacc gcacaacttg gaatcaaacc
     1141 agcaacacaa aatcctcgtg ttattaacta catggatgaa atcattgcat ttgtatcaat
     1201 cttgattgat aaaggttttg cttatgtttc tgaaggtgat gtatacttcc gagtaactaa
     1261 gtcaaacaat tatgctaaat tagccaacaa gaccttggaa gatcttgaaa ttggtgctag
     1321 cggacgtacg gatgctgaga cagatcgtaa ggaagatcct ctggattttg ccctttggaa
     1381 agctgccaaa gaaggagaga tttcttggga aagtccttgg ggacctggac gtccaggctg
     1441 gcacatcgaa tgttctgtta tggcaactga aatccttggg gatactatcg atatccatgg
     1501 tggaggtgcg gaccttgagt tcccacacca tactaatgaa atcgcacaat cagaagccaa
     1561 gactggtaag acctttgcta attactggat gcataacggt tttgtcaatg tggacaatga
     1621 gaaaatgtca aaatccttgg gtaactttgt gactgttcat gatatgctta agacggttga
     1681 tgggcaagtg cttcgcttct tcctagcgac acaacagtat cgtaaaccaa ttaactttac
     1741 cgagaaagct atccatgatg ctgaagtcaa tctcaagtat ttgaaaaata cgcacagtct
     1801 accactaaca gaagaggtaa gccaagccga attgcaagct tatcttgatg ctttccaggc
     1861 ggctatggat gatgacttta atacggcaaa tggtgtgact gttctgtttg atatggctaa
     1921 atggattaat tcaggcaact atgatgaaac tgttaaaaat gcttttgaaa aaattctaca
     1981 agtcttcggt attgttttcg aagaagaaac tcttgatgaa gatatcgaaa aactcattga
     2041 agagcgtcaa gcagctcgtg ccaacaagga ctttgcgaca gcagatcgta ttcgtgatga
     2101 gttagctgct caaggtatca aacttcttga taccaaggag ggcgtgaggt ggacacgtga
     2161 ctaaacacat tgatgtaaat cttattaatg gtattgcact cgcctttgag ggagatgctg
     2221 tttattcctt atacattcgc cgtcacctga tttttcaagg acagactaag ccaaatcaat
     2281 tgcatcgtct agctacacgc tatgtttccg ccaaggctca agctagcctc attgaaaaaa
     2341 tgctagagcg agagcttttg actgaaaaag agctggacat ctacaaacga ggtcgtaatg
     2401 ctaagagtca taccaaagct aaaaatacgg atgttattac ctataaaatg tcaacaggct
     2461 tcgaggcagt catgggttat cttcatatga ccgaggatat cgaccgtcta gaagagttgg
     2521 ttgcttggtg cattgatgaa gttgaaaaag aaatctaaaa attctgctga gagcaggatt
     2581 ttttgttgtt taaaattcat ctagattgtg aaaaataaac gatgtctaaa aatcaagatt
     2641 gtttgagaat caaagtaatt cagtgtttta acaataaaaa taagataaaa ctgatattta
     2701 gaggctttaa aatgaggaaa ttaaggagtg tctgacacgt gtaatcccga tactataacg
     2761 ttttttaata aaactctttt aacagaaagt taaagaagtc tataatgtta gtaaatgagt
     2821 ctatatcaaa aatgaggagg tgaatgaaat agctaaggaa aaagttttct atacaacttt
     2881 tgttgttttg attttgtcta gttttatgtt gcaaacaggt aaagcagacg aagttcaggt
     2941 gaaatctgat gaagctaaaa tagattatgt taatagtgag gcatcagctc cgtaagttga
     3001 tttttcttca gttgaagccc aggtagaacc acccagtcaa gtaagctcag tggtaacctc
     3061 aacgtcactg atggttttct cttcatgtga gacagatgag gcgcttcttg aggtgcattc
     3121 tcaagttgat attgtagaaa cgagtgtttc tatggctaaa cctcattcag aagaggctcg
     3181 tgtccaggct cttggtgagg accgatcagt agctggatct gagcgaggag attcaagccc
     3241 aatatctgaa gtggcttaag aaactgatag atctcttgta tagacaactg cagaaataag
     3301 tcagttggat aaaagtatag attgagaatt tgatctattc gtcagaagta acctttacag
     3361 acgaacttat ctcagagatt tccggaaaca gttcaacaag tgcaggatca attgacatct
     3421 tacaagcagc aggtaaaacc gttacccagg ctgcgagaaa gattgcggaa tcaattgcag
     3481 atctagatac aattggtaag cagactttgg ctgctgcaag ggttgtttta tttcttctag
     3541 tgctttacct agcggaaatt acatttattt aataggcttt gccctcgtaa gagtgctttt
     3601 tttatgatag aatgggcata tgaaaacaac taaagaatca atcctagaca ttgtttatgg
     3661 tgtgcatgct gtaacggaga gtctagaagc taatactgga aacaaactct atattcaaga
     3721 cgatcttcga gggaaaaatg tggatgctat taaggccttg gcagctgaaa agaaggtttc
     3781 catctcttgg acaccaaaga aaaccttgtc tgatatgaca ggtggggctg ttcatcaagg
     3841 tttcgtcctt cgtgtgtcag agttcgctta ctctgatctc tcagttatta tggataaggc
     3901 tgagcaagag gagaaccctc tgattctcat tttagatgga cttaatgatc ctcataactt
     3961 tggttctatc ctacgaacgg ctgatgctac tcaggtgaca ggagttatta ttcccaagca
     4021 tcgtgctgta ggggtaacac ctgtcgttgc caagacatca acaggggcgg tggagcatat
     4081 tccgattgca agagtgacta atcttagcca aacccttgat aagctaaaag aagcaggttt
     4141 ttgggtattt ggtacagata tggatggtac agcatctcat aaatggaaca cagctggcaa
     4201 gcttgctctt atcattggta atgaaggtaa ggggatctct gctaacatca agaaacaagt
     4261 tgatgagatg attactattc ctatgggtgg ccatgtgcag agcctaaatg ccagtgtggc
     4321 agctgcggtt cttatgtatg aagtttatcg aaaccgattg taactatgaa aaaaagaata
     4381 cttctggttg atggttataa tatgattgcc ttttggaaag aaacccgtca actctttaag
     4441 atcaatcagc ttgacgaagc tcgtgaaaca ctgcttcgta agcttaatca ttatgccaac
     4501 tttgagcata ttgatatcat ctgtgtgttt gatgcccagt ttgttccagg gaatcgtcag
     4561 cgctatgatc agtaccgtgt cagtgttatt tttactgagg aagacgagac agctgatagc
     4621 tatattgagc gctcagcagc cgagatgaat actattcaaa atctagttga agtagcaact
     4681 agcgacttaa atgaacagtg gggcatcttt tctcaaggag ctttacgtgt ttcagcacgt
     4741 gagttggagg agcgtgttaa taccgttaag tcggatttag acaagatgtc agcacatatt
     4801 gacttaacaa cccccaagtt acgtccatgg gacgaaacac aattaggaaa attacagaac
     4861 cttttaaatg aaataaaata gagggatata tgacatttaa aattttgaca gattcaacag
     4921 cagatctaga tgaaagatgg gctcaggaga atgatgttga acttattggt ctaaccatta
     4981 cgctcgatga tattacttat gagaccgttg gccccaatcg attaacgagt gaccgtctgt
     5041 tggaagctat gaaagaagga ggtcaaccga ccacaagtca ggtgaatgta ggtcaatttg
     5101 aagaggtttt tcgtcgtcac gctcaaaatg gtgatgatct cctttatctg gccttctcat
     5161 cagtgctttc aggtacttat caaagtgctg ttatggcgcg tgacatgatt ttggatgagc
     5221 atccagaagc tgtcattgag attgtagata ccctggcggc agcaggtgga gaaggttatc
     5281 tctctatctt ggcggcagaa gctcgtgacc aaggtaagag tttagccaaa acgaaagcca
     5341 tgattgagga cattctgcca cgtttacgaa cttatttctt agttgatgat ctctatcatc
     5401 ttatgcgtgg gggccgtctt tctaagagct cagcaattat tggtagtttg attaatatca
     5461 agcctcttct ttggctagac gattcgggta agttggttcc tttggctaaa atccgtggac
     5521 gtaaaaaagc cattaaagaa atggtgttgt atgctactca ggatattgga catagcacag
     5581 cgattgtcgc ttatgctaat gatttagaag ctgctgagaa tctaaaagaa caattgttaa
     5641 cagttaacgg cattgagcaa gttcttatta tgccactagg tccagttatt tctacccacg
     5701 tcggaccagg gacattagcc atctttacga ttggtgagaa agctagataa agttaaagta
     5761 aaaagagtag taaaatgctg ctcttttatt gtaaaatggg actgtcaggt gaatttgaca
     5821 cgatgtaaag gcaccttagc taatatgtca aggatattgg atagtgtttc aaaacgaaaa
     5881 aggagataat gtactcgtta cgtcagtagc gaaaggagag ttttataatg aatatcaacg
     5941 aattaagaaa aaagaataat cttagtcaag atgggtttgc taatttattc catgtatcta
     6001 gacaaacggt ttctagttga gaaaatggga aaagttatcc cgatgttgaa atgctcatta
     6061 aaattagtca acactttgga atctcagttg atgacttagt caaaaatgaa atgcaattga
     6121 cgactaacaa caaatccaag acgaactctc gcttatggtt gattgctcta ccaatttttg
     6181 tcctcatttg tgtaatagct gttggtagga ataaacacaa tagccaatca gttaattttt
     6241 ccatgaaaga tgataaaact tataaaagta atgatgcggc acaaacctct ctgacagtgg
     6301 ctaaaggata ttttacagtt ccaaaagctg gtaaattaga ggtcaaggtt aatgcgacga
     6361 cagataatgg caaccttcac ctaactatcg tagataataa tcatcatcac tattatcaaa
     6421 tagatggtga tgacttaaaa gattcacaaa agctctattt taaaagtgga gactattgta
     6481 ttcgcattac agccgatgct tatacagaaa aagttgttag tttggattac aatattaaag
     6541 ttaatagtta gtgacttgtt tgaaaaagca catgaaatct ttcattgctt tatttatagg
     6601 ctttatttat agctagccat aagaaaattt tatacctgat ttcctccata ttcgactgat
     6661 gaagtgatat aattttttaa atcaaaggag gaaaagacat ggctttgact tatgctgtac
     6721 ttggaagtgg tgcaatggga ctacgttttg ggctgctatt aaaagaacac ctcggtgctc
     6781 aagtggattt tattgatacg tgggaagagc aaatcgacac ggttagaaaa caaggtggtg
     6841 tttatcaatc acgtgatggt aaaaatcgtc atctgattcc aattagcatt cagacaccag
     6901 aagaatacca agggaaacca gatgttttta tcatttttga taaacaaatg catttgtcac
     6961 agttgctcga acgaagtaag catttcttcc acgaaaatca atatgttttc acaggaatga
     7021 atggcatggg acatatcgag aaaatcaatc gctattttgt gcctgaaaaa gttttagcag
     7081 gaacttgtct gattggaacg gtcttgaaag acgcaggaga tgttgatttt attggaaaag
     7141 caggtgctgg ttctattaat attgccgctc aatcagggac ggtcgatgat gttcaaaagc
     7201 agataataac tgaatttgaa gcctcaaacc tcaatccaaa tctgactgat aattttttag
     7261 gaacacttta cacaaaagtt gtgttcaatt ctgtcatcaa taccatttgc accctttttg
     7321 aaattcgtat gggacaattc attgattatg aaggtgccga aaaactagga cgtcaattaa
     7381 ttgatgaagc ttataacgtt gccgaattag cgggcattac tcctctgaat agtcgtgatg
     7441 aagaatggga gactattcgg tatgttagcg cggaaacaag ccctctgcat tatccgtcaa
     7501 tgtaccaaga tatgaacaaa ggacgtcaga cagaagttga ttatatcaat ggttatatct
     7561 atgatttagg caggacttat aattaccaag caaaaacgca tgacttttta cgccacttag
     7621 ttcacttagc agaaaatacc cgtaaattcc gctaagcgtt ttctatgaaa aagaagaaaa
     7681 aatcgctaaa aaacttagaa aagatggtag gtaagtgttg ccttggactt gtttttttga
     7741 tattatgtta aacggtattg tttaccccat ttgaaaggcc ccggaacctt ccaaatatac
     7801 ttttcgatgg gaagggacac ccatcactcg taaacaaaaa tcgaactata tataggagaa
     7861 atcatgaaca aaacaacatt tatggctaaa ccaggccaag ttgaacgtaa atggtatgtc
     7921 gttgacgcaa ctgatgtgcc acttgggcgt ctttctgcag tagttgctag cgtacttcgc
     7981 ggaaaaaaca aaccaacttt cacaccacac actgatacag gtgatttcgt aatcgttatt
     8041 aatgctgaaa aagttaaatt gactggtaaa aaagcaactg ataagatcta ctacactcac
     8101 tcaatgtacc caggtggttt gaaacaaatc tcagcaggtg aacttcgttc taaaaacgct
     8161 gttcgtttga tcgaaaaatc agttaaaggt atgcttccac acaatactct tggacgcgca
     8221 caaggtatga aattgaaagt cttcgttggc ggtgagcaca ctcacgctgc acaacaacca
     8281 gaagtacttg atatctcagg acttatctaa ttctaagagg aaaggagcac taatataatg
     8341 gcacaagcac aatatgcagg tacaggacgc cgtaaaaacg ctgttgcacg cgtacgtttg
     8401 gttccaggta ctggtaaaat cactgttaac aaaaaagatc tagaagaata catcccacac
     8461 gcagaccttc gtctcgttat caaccaacct ttcgcagtta cttcaactga aggttcatac
     8521 gacgtacacg ttaacgttgt aggtggtgga tacgctggtc aatcaggtgc gatccgtcac
     8581 ggtatcgctc gtgcacttct tcaagtagac ccagacttcc gcgattcatt gaaacgcgct
     8641 ggacttctta ctcgtgatgc acgtatggtt gaacgtaaga aaccaggtct taagaaagct
     8701 cgtaaagctt cacaattctc aaaacgttaa tcaatacgat tatatcaacg tttcaagaca
     8761 ttcaagattt ttatcttgga tgtctttttt ttgttgaaat ttataaagtt caccccaaaa
     8821 ttcaccccat gttcacccta ttattttttt aagcttctat atgcaatatc tccagcagtt
     8881 tgatttacta tatttttgtg ttaacatagg tctttgtaat ttgtttatca ctatgagtta
     8941 atgcctcgga aataatttct aggggaacgc cagattttct tgcaagagtg gcacctgtgt
     9001 gtcttaactt atgtggtgaa gcaggggata gttctggatg cctacgtctg acagaattca
     9061 ttctatagtt gaggtaatct gtatgaagtg gaaggttgat attattggat cggtcattat
     9121 aggtaaacac aaactgcttt tgagtctggt gtaaaccaaa tagttttaat tccttattat
     9181 gaaacggttt actttacgga ggagttggcg catgactttg cctcatgggt gtctggagat
     9241 tctatggagc caaagtatca caatggttca gttgctctca ttcgtgaaac aggttttgac
     9301 tatgatggtg ccgtatatgc tgtggtatgt aatagtcaaa catacattaa gcgagtatat
     9361 cttgaagcag agggtctacg tctaaagtat aaggatatct ttatttctta tgacgaggat
     9421 ccacgagtag tgagaattat tattggaaat tttatacctc tcaaataata cgtttttcta
     9481 gtcctgaatt gtcaacttgt ttgctttttt gataatgatt ctagttttca aaaatgtaat
     9541 gacatctgtt aaggatttct tatgaaatat cttctgataa cagagcttgt ttgatagtac
     9601 agacggattt tattttataa tactccgaaa caaaaagaat gaattttcta aaaattattg
     9661 acaaataaat ttgcttttag tattataaac acaacttaaa gaagaggcag agttatcatg
     9721 gaaaatactg aattttcatt ggaacttgat gtaactgaag tttcaacaga acaaggttat
     9781 gtttctggtg gtgtaacatc tacaggttgt tgtaaagatt agttttataa ttgattgaat
     9841 aaggcaggta tacgaggtac ttaccttttt ttacaagaga attatgttta agataaaaga
     9901 taattacatt tataggtaat gcgttaatga ttcaagactt atagaaaaac ttagtgaaaa
     9961 taatcttgaa atattttttg ataacaaagt ttttaaagaa atgttgctag tggcgaaccc
    10021 tcaatttttc cataatttaa ctaaagaaaa aatatataaa aattccacct ttagaaacta
    10081 tgtaaaaaga tcaattacaa gagcaacgcc gtttggattg tttagttcaa ttggtgtagg
    10141 aactttttct gatatctcat atcatcaaaa gattggagaa aattatacga aaaaaatctc
    10201 ggttagtgga gagtggctaa gttcgatttg tatgatgtta gaaaataaag attctgtctt
    10261 attacaacta catatatagt ggaaccaaaa agtacttgaa ttatcagata agtatcaatt
    10321 aagtaatgtc aattactggg gaatctctga gataagtaag gatttattta tcaagaaaac
    10381 tggactttta gaattcatac aaaaattaac gtataaatcg gaagtcagtg tgttagaact
    10441 ggtacttcaa agtaaatctc ctgatttaga gaagcagaaa attttagatt atatacgtaa
    10501 tttgattact aatgaatttt tgtttacaaa cttgcgaaaa gttgcaataa gccataaaga
    10561 tttagatgat ttaaccaaca ttttaaagga tattaataac caaagaaaat taaccgagga
    10621 tttattacaa ataaaaaata gtattgagca gtatgcaaaa ttagagttgg gagaaggcat
    10681 ttctcaatat actgaaattt gtaaaaaaat gtcgtatatt tttaatgata aaaaacagca
    10741 ttacctgaag gtggatttag taaattgttg tgattcggtg ctgcccaaaa atttaaaaaa
    10801 gaaaatggag gattttgtta attttatttc aaaaattaat ctggctaaag gttatcgaaa
    10861 cagagaatta gaatcattta cagaaaaatt tgttgaaaaa tatggagaat acgtcgaagt
    10921 tccaattaaa gaattattag atggtaattt aggactgggt ttaccaaaac aaactttggg
    10981 aactcatgta aagtcatcaa gtagtgtaga agagcaaaat tttttgtctt atctgagtaa
    11041 agaagtcttc aaagctgtta aaaattgtaa aaaagagata gatatatcaa atataccttt
    11101 aggattgtta tacccaaatt cggatagatt tgttgcaaat cagttagagt tatattgtga
    11161 aattaagaat tttgaatctc aacctgttat atcagttgtc ccaaatacag ggagtgacat
    11221 gatagggaag tctattggaa ggtttgcctc ctattttcct aattcttata tctcgttaga
    11281 ttcacagttg gataatgtag aattaataga atttccaaga gatagtaaga atttaaatgt
    11341 tatgtcggca cagaatgctc attctaaaaa gttattatta tcttatgatg acaatgataa
    11401 cacatcgatt gaattagatt ctgtggtggt gggggttata aaaacagaat atcgatataa
    11461 attatatttt agggatttac gaaccggctc aattgttaat tttgtaacaa catcaatgct
    11521 aaatcataaa tcaaatggag tatttagcga tttagcaaga tttttgctag cggtttcttt
    11581 agaatggcaa gataatccgt tttcagtgtt taggataatt gaaaattttg attatcttcc
    11641 ctatattccc aaaattaaat atggaaatat aattttaagt gaagagaagt gggttttgtc
    11701 agatatagat aaaaatgatt tatcttctat taaacagtgg aaaaaagatt ttgatgtacc
    11761 tagactactg tattttcata aagctgatga gcgtctattg gtcgatttag agaatgattt
    11821 agatacacag tggcttttaa aacaaaatgt ggataaactg tattttacac gttttgaaaa
    11881 atatgatggt aaaaattgtg agtttatctt tggatttgaa aattatcaaa gtagtataaa
    11941 tcattattct atgcaggaaa aatctgttag aagattgaca aataactttt ataagaacta
    12001 tgttaaaaca ttttcgagtg attggatcta ttttagatta tatggaatta attcatcaat
    12061 tctacttgaa ctaagagagc ggcttctttt gtttacagac gagctattgg ttgaaaagct
    12121 aattagtgat tttcattttg taaattatag cgataaggat aatggatcgc ttcgattacg
    12181 atttaaaata aataacgatg ataattttga agatttaaga tttcgaattg cacattggat
    12241 agacttccta ctagaaagtg gtttttgtaa tgatgttagt tttaatttat atgagaggga
    12301 aattgagaga tatggtggag ataactttat aacagtttgt gagaggatgt tttctattga
    12361 cagttttctt accctaaagt tattttcgaa gaaattatta aatgataaag atttattttc
    12421 tgttttgcat tcgacatttt tatatattcg attattaggg atcccattaa agcgattact
    12481 tgagttgctg aaggggaatt tgactcaaaa tagatatcgt aaaagtttta aaaagttatt
    12541 cccaaataac acaatagtag taaaggaatt caaagaatat tttgattaca aaaatcagtt
    12601 tgaaattttt aatgaagtat ttagagagtt cccgcctatt gatggatatt ttgaaggtaa
    12661 aaatgatata gtctatagtt tacttcatat gcatatgaat agagtaggca tgtttccata
    12721 tagagaaaag gaatatcttt attttatcat gtatattgca gagccgttga ataattataa
    12781 ggaatttact taaaaagtat gaagaaatta tctgtaaagt agataaactc gtgttggata
    12841 gtgatattat tgacagattg cagagagcat attatacaga aaatagaagt tacttatcag
    12901 aatatccaag tataattata tatttatcct ataggttgat aaattgtgat aataaggagt
    12961 attctaagct tctctataat agagtaaatt attatctaca agaattgcta aagtctatta
    13021 aattgaatag cactaataat atttcacttt gctatggatt tacgggctat gtatatgcct
    13081 tggaattttt atctaaaaat tgtaaaggat atgataaatt actagataca cttgagacaa
    13141 ttttattagc tttaacaaaa gataggctac gtgaaataaa aagctctaat attgttaaag
    13201 aagaatactt tgatgtaatt caaggtgtct ctagtgtagc tagatatttg cttagcaaag
    13261 aggaatcaac ttctgaacaa gagttattag taaaagaaat attaaattac tttgcagacc
    13321 taataattaa cgagccaact atttatgtgg aatatatgcc aaatgaaaaa ttaaggaaaa
    13381 gatttcctag tggctatatt aatctaggtg tagctcacgg tatattggga ccactatacg
    13441 tgttggcgtt aggatttgaa aaatttaata taacaaaaca cataccttca atagaaaagg
    13501 gcttgagtta ctatgagaac gcctttttta ccaatacaat tggaaaaata attggttgga
    13561 atggtagagt cagtgattat gaggagaatg aggaatttag atttaatata agttggtgct
    13621 atggcagtct tggaatggca agagtactat ataatatagc gaaaatcatt gatagtcaga
    13681 aattacgaga aatggcgatg gatgtattta cttcatctat tgattacctt aatagcagtg
    13741 agattttaaa taatggaatt tgtcatggac ggtctggaat aatgcttttg ttcaatttga
    13801 tgtatttaga tacaggaaag acacaattta aagcaatttc tgataattta tttaaagaaa
    13861 ttataaatga tgcttctaat tctgagtata tatttgtgga gcgtgacata tattttagag
    13921 gcgtaacctt tgatgaagtt attgattata ttgactttgg attgctaaat ggtgtttcag
    13981 ggatagttat aactctaatg gcacaaagga ctggaaatgc ctacccattg gatagaatgc
    14041 tgtttatgca gtgaagtttt taagttaaag gagaagtatg agaaaaatct taaaaaacaa
    14101 actatatcta aaagttctgg tttcggattt gatatcaaat tttggagata cattatattt
    14161 tatagctctc atgacctatg ttacggagat taaggagagt aatttagcta tttcaatcgt
    14221 aaatatatcg gaaactctac ctattttatt tacaatattt tttggtatca ttgcagataa
    14281 aacgcttaat aaagtgaaaa tgattattaa aacgttatgg ctacgggtga ttctatattt
    14341 attggttgct gtggctatga attttaaacc ttctattata gtagtcataa ttgctagtct
    14401 cattaatctt gttgcagata cattgggaca atttgaaaat ggtctttttt atccaatttc
    14461 taatcgaata gtgaaaaagt cagatagaga agaaactatg gcgtttaggc agactgttgt
    14521 ttctacgatg aatattgtaa atcaatcatt gggggcgttt ttaattactt tttttagttt
    14581 ttctcactta gcttttataa attctctaac ttttgctatt agtctgttaa ttatgttagc
    14641 aatcagaaat caaattaata gctattatga cgagacgatt tcgactagta agatatctca
    14701 atttgacttt aaagcttcat tttctgagat tatttcaaat ttaaagctct cgattaacca
    14761 tctatttagt atcggaaaca tgaaggaagc tttacttgtt atacctattc tcaatgggag
    14821 tttggcaatt ctcattccat tagttgttgt taatctttct aaagattcta atttgacaat
    14881 tgttaattct gcgattacga tctcgctttt aggaattagc actgtttcag gaggaatact
    14941 tgggggcact ttaattctaa ttagtaaaaa atttaaaagc ctttccatag gcactttgct
    15001 aaaaatgaat ttaacgattg ttttactatc attcgttgct ttttacttcc aaaatattta
    15061 tttaattata ttatcatcat ttctttcgag tgtattagtt agtgcattaa atcctaaaat
    15121 ggggactatc atatttaata atattgatga gacgaagttg gctacaatat ttggaggaat
    15181 ggtgacatat ttccaaatag gggatattgt gtcaaggtta ttgttttcta cattagtgat
    15241 ttacttaccg tatggttata tcgcattaat atatatagca gttgtttttg tggcaatttt
    15301 atatacatta aaaagttcaa atcacataga aagggaattt taaattagtt aaatgattat
    15361 agttttccaa attttctact atgaaaacct attttcaaga ttgagtacta aagttcgaga
    15421 ttttgttcgt actcagctta gagaatttca atatttggat gatgggcaat ttaaaacatt
    15481 accagagtat ccagaatttg cttggtttga agggatgtaa atgcggtaac tcatagaaat
    15541 tgctccattt ttggcgatta tatccgaatt atgatgtttg atgatcgatt agaaatttat
    15601 agtccaggta agcttcctaa tatcgtaacg gttgaaaata ttaagcacga acgtttttct
    15661 cgtaatcctc gtattgctag aactttaaca gaatttggat gggtacgaga aatgaatgag
    15721 ggagtgaagc gaatctattc tgagatggaa tcttatttct tgcatgaacc taaatacaca
    15781 gagccaggaa ataaagttgt tttaactctt gaaaataata ttttgagccg acatttgaga
    15841 gttaatgata agatgatgaa aaaatatgac gaattcaatg atttaaatga cgatgagaaa
    15901 gcaattttac atatcatgta taataccgga gagaaaatga ctactgcttt ggccgctaga
    15961 ataacaaata ggggtagaaa ttttgcaagt aaattattaa agagtcttgt aaataaagag
    16021 atcctggaat ggcatggcac aagtaagcaa gatagaaatc agtactatac tttggcagaa
    16081 tagcggatct atttataact ggagtgcaga agagtgcagt agttcggagt aaaacgcagt
    16141 aagtgaattt cccctgtttt cctcaaaaaa tctcaaactt tttgaaattc tggacaaaag
    16201 aaaaggccta gttgcctgta gtttctacct attaagttat attgaaattc attggtttaa
    16261 aaccagatct taagaaagct cgtaaagctt cacaattctc aaaacgttaa tcaatacgat
    16321 tatatcaatg tttcaagaca ttcaagagtt atctcttggg tgtctttttt tattcaaaat
    16381 tcgatagttt ccaccaaagt ttccaccaat tttccaccat tattttttca agctacgaaa
    16441 tgcaatatcg cctactgtcc gattaactat atcttttgta tttacataag tctttgtaat
    16501 ttgcttatca ctatgagtta gagcttctga aatagcttca agagaataac ctgcttgttt
    16561 ggcaagagta acacctgcat gtcttagttt gtgtggtgat gctggtgcaa gttctggatg
    16621 tctccgtctg actgacttca ttctataatt tagataatcc acgtgaagag gtaaattaat
    16681 gttgtttgaa cgatcattat aggtgaatac aaactgcttt tgagtttgac gcaatccaaa
    16741 taattttaac tcctcttgtt gtcttgcttt ccaattagct aatagctcaa ttaattcaat
    16801 aggtgtttta aaaagggtct tcttacgacc tttggtgggt tttatatttc cgaaacgatc
    16861 taaagcttgt tctatcagtg tttctccagt agagaaattg atgtgtttcc attgaagagc
    16921 ataactttct gattttctat cggataaaaa gaatgtcgta taaaagagag tgtagtcttt
    16981 taaatcaata agtcctttct ctaagtctat gtcaaaagct tgtaaccata atttcagctc
    17041 ttctttatcg agagataaat cttcctctcg tttgctttct ttaaggagaa tctttttatt
    17101 agctttaatt ctagtaattg ttttgcggag tttatttgat ggaatatatt ctagttcctc
    17161 agcccaatcg aaaacagaat taacatggct cctaattact ttgaaattag catagctatt
    17221 tgctttggga gtaagtaatg aaagaataag ttgtttatta ttatttgggt attcgataga
    17281 atatttaccc agaatgggta aaatgtgtag cctgaatata ttttctgttt ggaaaactgt
    17341 tgcttttgtg ggtggtttta ttgttgttgt ggtttgacct gctttgtatg gttcgagcca
    17401 aatatcttca taaaattttt tgaatatgat ttctccttta ttttttatgt ttatatggct
    17461 ttttccagac ttagcatttt taatgtcgat agaaagtttt aattctactt ctttggcttc
    17521 tcgtctggtt ttatattttc tttcaaaaag tttacctaaa cccaattttg cttgaacatc
    17581 ttctggaatg taaagtcgta attgatatgt tccatctttt gttttcttaa tagacatatt
    17641 tacctcctta tgcgctgatt tctaatcttg tcatccattg attgatactt ttcttgttga
    17701 aactaataga ttttccgatt cggatatagg gtaatcccat tgcaatccca atatcaagtg
    17761 tattattaga gatacctagg tagttgtaag tctgtttttt gtttagaaaa gtgctgtcag
    17821 ccccaatatc ctctttaaaa tgatgaattt cattctttat tagtgttgca atcatttgct
    17881 gaatttcttg agtttgttct tctggcaatt gtactagcat atattattct cctcttaaaa
    17941 ataaaaaaga agagtaaaat actctcctgc tgttaaaaag attaattctt cttatttatt
    18001 attttgttga aaaaaactag caaagcgacc ccgaccactg tcaattgttt gcccttatta
    18061 cgacatgcat cacaaattgg tattgtttta ggtgatgaga ttgttttttt acaagtttta
    18121 cacttcttcg tttttagtgt catttttttc tccgtttcga tttttgctgt ttcggtattg
    18181 cttaagttaa cgttactatc ttggtggaat tcaattaatt tagtattaat attaataaat
    18241 aagtccctat tgttttttga gtagctgtaa tgattatgaa ttaattctaa caaacttact
    18301 tttgggatac tattattctt tatccatttt aattctttta cataaagaag tttttttgct
    18361 agttctttca aataatttgt tttgtatgga atattttgtt tagaaactaa ttccatcgaa
    18421 ccttgaaaag atagtagccg atcatgggct atcccctcat tatttagtgt taaatcgata
    18481 taaatttgca taccaacaat tttagtcata atttctatgt cttgaagtaa aaaatcagca
    18541 tgtgtttgta aagaggcttg acggtatgtt ggttggctga ttttcttaat aatttcatct
    18601 ctatttgaaa ttatatcaga tttaatagca cttactgatt cttcaaataa tgtatttgca
    18661 tcctttagtg acttaacttt ttctctgaaa tctttgctat tgttggcttc tataactttt
    18721 gtacgagctg aataaaatgg agctagtata ctattatttc tttcccatct aatctgataa
    18781 tcttgatttt ctttgatatc taacagtaag ttatagattt gtttaagttg agcttgagcg
    18841 attagatcac taggaacttg attttcgttg ttattagtca ttttccttaa tgtcaaatct
    18901 tcaacacgat tcttctgatc ggttgtgtct acaattacag ccctaagatt tccttctact
    18961 tttctagatt ccccaatttt ataagcgccc tcttgaagtt tcgctttggt gtcaggagat
    19021 agactgtcaa agtcaacctc atatagagta gcattattga aatctagtat tttagtgtta
    19081 ggattaagat attggtttga aaagttgaat ggaggggttc ctttagtatc aaataagttt
    19141 aagatatcaa atgggaaact ttctttaatc atgttgggga gagcttgttc aaaaggacta
    19201 cttatttcaa agatatctgt tgttttgata tctgtctcat ttttaaataa atcaaaagat
    19261 tgtaagtttt tttgattgat tcttcttttt gcttttctga tttagcaact tcgttcatta
    19321 gatcacctag tcatttttgt attaattata acatttagta ttgattttaa acgtatctaa
    19381 attaataata ctaaaaatta atattattaa aaccatcatc agtgtccaat gacataagta
    19441 atttgttttg ctgtttctgc atcaaaagtg cggtagctaa cgactcctag tcctttgata
    19501 tttgattcag agatgaggat ggagccatct gatttgactt gttccacaaa ggcgatgtgg
    19561 ccataagttg gatctgctcc agcttgccct gggctaaaag atagagcgga gtgttcggtt
    19621 ggggtatgag ttgtctgata ccctggggca tttatccatt ggccaccatt tcccatatac
    19681 tttccgaagc taacaccgac ttcttttcct cggttataga caaaccaggt acattgtccc
    19741 caaggataag acagtcctgt gtggcttgag gtattgattt ctttggtgag gatatagcct
    19801 tgtgggacat cccctgttgt gacaccgcct ccgtctctgt tttttccttt cgtctgttca
    19861 ggggcttttg gtgtacctcc atgctcatcg atataggtat cgagtttttg catggtttca
    19921 gcacgccctt tcctagagcc agaggtatcg gtgaagtaga cgccaccatc tgttgacgtg
    19981 ttgagagaac cactcgcaaa tttttgcgct ttgtcatctt ggacttttaa ggtttcattt
    20041 ttattgccaa tgatggtctg ctttgtgagt ccaacaacgg ctacttcatc gttaaaatta
    20101 ttggcatttt ctggattaga gtcaaatgcg gttctgttgc aaagttttaa ataaagaata
    20161 aaatccctta cggtatctat gatttaagct gggattccca ataatacctt gatttcagta
    20221 cagaccgaaa agccgaagag agtgccttct tttcgggttt tcttatataa tcctcgaatg
    20281 gcttccatgc ctttaatcgt ggtagaggca atgcgtaaac ttcgatagaa tttattgcgt
    20341 ctctttactg gacgatggtc ttgttcaatc aaattgttca ggtatttaat ggtacgatgt
    20401 tctgtccctt gataaaagcc gtattctttt agtttcttaa aggcacttgt aatagagggg
    20461 gctttatctg tgactacaac cttcggttca tcaaactgct tcactaaccg cttaagaaaa
    20521 gcataggctg cttgtgtgtc ccgtttttta cgtaaccaaa tatccaaggt taaaccatct
    20581 gcatcgatgg ctcgatacaa ataatgccat tttcctttaa ttttgatgta cgtttcatcc
    20641 attttccatg aataaaagga ttttttattt ttctttttcc aaatttgata gagtagtttg
    20701 ccatattctt gcacccaacg ataaatcgtc gtatgagaaa cgttaatgcc acgatcatat
    20761 aagatttctt gaacttcacg atagctaagg ttataacgaa gatagtagcc cacggctaca
    20821 ataatcacat cctgctgaaa ttgctttcct ttaaaatgat ttatcgtcat tcctcctgct
    20881 atctttttct attattctaa cttatttgat agtagattta aaactttgca acagaaccga
    20941 tgtaaccgtt tattaatctt ttttatcatc tatggataac atttttttgt tacactagga
    21001 gtatgaaaaa ggagatatga tgaaacagag ccaagctaaa aagcatgaca atacgatgac
    21061 taataagatt ttgatgaggt tgattgctct tgtcttaggt ttgctttttc ttgaaatttt
    21121 gattattcat agtaaaaatg agcagcaaaa gagtgtttca aatcaagtac agacagcacg
    21181 tatcatggct aatggggact tgctttatca tgacggtctc tatatgagtg ccttgcaggc
    21241 agatggcagt tatgatttta ctgaaaattt tacatatgtg aagccatggt taaagcaggc
    21301 tgatttggtc ttgggtgatt ttgagggaac tatcaatcct gattatcctt tgtcaggcta
    21361 ccctctgttt aatgctcctc aatcagtgac ggcagctatt agtgatgccg gctatgatgt
    21421 tatggatttg gcccataatc atattttgga ctctggttta gagggagctt ttacaacagc
    21481 cgatgcattt aaagaggtgg gcattgaccc tgttggtgtt tatgaaaatc ctgtgcgtga
    21541 taaggcgcct ctgtttatca agaatgttaa tggcatcaag gtggcaatac tttcttatgc
    21601 ctatggtttc aatggcttgg agtcaaatct gaccgaaaaa gagattgcga atcatttgtc
    21661 gaatcttgat gaaaaacgga tgaaagtaga gattgagcgt gctgaaaaag aggctgacgt
    21721 tacggttatt atgccacaga tgggcgtgga atatcgtttg gaaccgacag atgaacaggt
    21781 aaagctttac cataagatga ttgattgggg tgctgatatt atctttgggg gccaccctca
    21841 tgtggttgag ccgtctgaag tggttaaaaa ggatggacag caaaaactca ttatttactc
    21901 aatggggaat ttcatctcta accagcgcat agagactatg gatggtgtgg atagtgcagc
    21961 atggacagag aggggcgtct taatggatgt cactcttgag aaaaagaatt gtcaaaccac
    22021 gattaagaca gctcaagcgc atccaacctg ggttaaccgc acacccaagg gaacaatttc
    22081 gccagaggga tatcctttat atacttatca aacctatatt ttagaggatt tcattaaagg
    22141 tggaaaatac agaaataaac tagatgaaga aactaaagag cgtatagata ctgcctataa
    22201 agaaatgaat gctcatgtta atctaaaatg gaaataaagc taagatatcg ctaaaatttg
    22261 gcgatatttt tctttatcga caagttacca acagacttat ccacaggtgt ggataagtct
    22321 gttctcagtg ttaaaccttg atttttcaag gttttattag aattgtattg ttttacttgt
    22381 taacaagttt atccacaagt tgttgaattg atagagactg aattttataa acgatactgg
    22441 ttaaatgttg tagaaacatt cgtttttttc aataaaaaag gtgtaatttc tataaaaaat
    22501 agcgttttta atcaaaatat gctaaaatta tataaaataa aatgatggag gcttctcatg
    22561 aaagcgatta ttacagttgt aggtaaggat aaagcgggta ttgttgcagg tgttgcgact
    22621 aagatcgcag aacttggttt gaatattgat gatatcactc aaacaatcct tgatgaattc
    22681 tttaccatga tggcggttgt atcatcggaa gataagaaag attttacaca cctacgtgct
    22741 gaattagaag cttttggtga atcattaaac gtcaaaatca atatccaaag ctcagcgatt
    22801 tttgatgcta tgcacaactt ataagatagg ggtagttgaa aatggatatt aaacaggtta
    22861 cagaaaccat tgctatgatt gaggagcaga actttgatgt tcgtactatc accatgggaa
    22921 tttcacttct agactgtatc gattcagata ttgataaggc agcagaaaag gtatacaaca
    22981 agattgtttc taaggctaag aacttggtag ctgttggtga cgaaattgcg gctgaacttg
    23041 gtattccgat tgttaataaa cgtgtttctg ttactccgat ttcaattatc ggtgcggcga
    23101 cagatgcgac agattatgta ccgtttgcta gggcactaga ccgtgcagct aaggaaattg
    23161 gcattaactt tattggtggt ttctctgcat tagttcaaaa gggctaccaa aaaggtgatg
    23221 agattcttat tgattctatc ccacgtgcgc ttgctgagac tgattttgtc tgctcatctg
    23281 ttaatattgg ttcaacaaaa actggtatta acatgacagc ggtacgtgat atgggacgta
    23341 tcattaaaga ggcttctgag gcagatccaa tgggtccagg taaattggtt gtctttgcta
    23401 atgcggttga agataatcca tttatggcag gtgccttcca cggtgttggt gaggctgacg
    23461 ttgtaatcaa tgttggggtt tcaggtcctg gtgttgtgca acgtgctgtt gagaaggttt
    23521 caggtgaaag ttttgatgtt ttagctgaaa cagttaagaa aactgccttt aaaatcacac
    23581 gtgtagggca gttggttggt caaatggcta gcgaacgtct aggtgtcgag tttggtattg
    23641 tagacttgtc tcttgcacca actccagcag taggtgattc ggtagctcgt gtacttgaag
    23701 ccatggggct tgaagttgtt ggtacgcatg gtactactgc ggctctagct cttcttaatg
    23761 accaagttaa aaaaggtggt atcatggcat gtaaccaggt cggtggtttg tcaggtgcct
    23821 ttatcccagt ttctgaagat gaaggaatga ttgcagcagt tcaatctggg catatcaacc
    23881 ttgaaaaatt ggaagccatg acggctatct gttctgttgg tctagacatg attgccattc
    23941 ctgctgatac gccagataca acaattgcgg ccatgattgc cgatgaagcg gctattggtg
    24001 tcattaatca gaaaacaaca gctgttcgta ttattcctta tggtaaggaa gggg
//
