LOCUS       gnlProkkaNADAGIKK_10    5749 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NADAGIKK_10.
ACCESSION   gnlProkkaNADAGIKK_10
VERSION     gnlProkkaNADAGIKK_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 11:56:15
            Original ID  :: gnl|Prokka|NADAGIKK_10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5749
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5749
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[762:3450]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      763..3450
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..5749
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5749
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             89..748
                     /locus_tag="ctg9_1"
                     /transl_table=11
                     /translation="MDNICKLSFQLGKSKVNSLGSASIIIYKDEFFVATAAHCLYDVGS
                     NEIAKNISIEVENCGMKESYDVLNIVIPEKWISTHRLTYDYAFGWIKLPESMRNVAFIP
                     NFDLSGMIEEHNKAVTLAGYPISFFKSQKKYSKGDLDLTLFKEEQLIGMRSKLKHGISG
                     GPWFFESDNEKFQIGVTSARIKSFKNKVWASIWTKDTERILNKLLTSEMQEKIILA"
     CDS             763..3450
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 64.1;
                     E-value: 2.4e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_2"
                     /sec_met_domain="micKC (E-value: 3.6e-144, bitscore: 470.5,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.9e-19, bitscore: 57.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.6e-25, bitscore:
                     77.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYVEFLSPGNLFYELVTPNKIVNNYRIPNLNSEEWKQNTDIN
                     WSYCINTKKKMPKQGWKIHITTDIDEAQKTLDIVLPYLIENEISFKFVPNERQLLFKNS
                     KNGDRASSGKFITIYPYDNKTFLTLLSDLDNLTKALKKGPYILNDKRWKYSNVFFRYGA
                     FVSMYVNKDGQNVPAIQRPDGTLIPDVRAPYYEVPDFVEEPVEIQIMTKKVDAELDKED
                     TSKFDSYNVISALHFSNGGGVYKVEKNGKTFVMKEGRLGSGLDRLKLDGFKRIYKEAET
                     IKQLSEKPYIVDFYDYFEIWENNYLIEEHVSGISLMEYVSQNFPFSYKEDKDIYMERMM
                     HVIDQLIDALKDLHRSKIALGDLQPNNVLVLEDYSIKLIDLETAVTPESKYTPALMTPG
                     YVTDQAETFEQADWYALLRICRFLFLPIENLSDLSIDIEINQDKWIGENFGDAVLNKIQ
                     EIQEKTLPTIKKLSEAATLTIPPMKINYKNVNEITEGLRAGIMSHLKPKSESLISGDIR
                     QFIEKMGSLSIANGGFGGIMALDRTGTLSDSVYQWVDHVLETILNLDTETYKNFPLGLF
                     NGISGILSVLYDIGYKEEAIKLLETMPLPDTEDSDLTLFSGLSGIGLNYLAFYSITQKK
                     GFLDRSIKIGNRIIDAYKEDCSITVRDPYAMPYGLLNGWSGISLYILMLGKATNDNDLI
                     KLASEIFNKEISKNIEIDSKLELAQIKEYSLGYKRLIPYLGEGAAGIALIMLEFNKNLP
                     DFMTESNTELFKKLTNVTDLYSTFASGIFRGVGGMIILANAMKCEGVNTGSLEYTIKAL
                     GNYLLYKKQEGILSPGEYGYRLSLDLQTGNSGLLLALSDIDSDKWNSWLPLPKNNNLNL
                     FEIDKFIKGGETNEKAIISSAQST"
     CDS             3413..3541
                     /locus_tag="ctg9_3"
                     /transl_table=11
                     /translation="MKKLLSLQHKALDKEVTLLKGKSSVSLGCDKISTVSLYFCGN"
     CDS             3578..3706
                     /locus_tag="ctg9_4"
                     /transl_table=11
                     /translation="MKKLLSLQHKALDKEVTLLKGRSSVSLGCDKISTVSLYFCGN"
     CDS             3744..3872
                     /locus_tag="ctg9_5"
                     /transl_table=11
                     /translation="MKKLLSLQHKALDKEVTLLKGKSSVSLGCDKISTVSLYFCGN"
     CDS             3989..4171
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_6"
                     /transl_table=11
                     /translation="MSRGKQISNILKLQSLESGPVYTAGATGTVEGQSLISPASIAFCL
                     TPLPVSTMSAAFCNN"
     CDS_motif       3989..4069
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MSRGKQISNILKLQSLESGPVYTAGAT"
                     /locus_tag="ctg9_6_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4070..4171
                     /prepeptide="core"
                     /locus_tag="ctg9_6_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-3.30"
                     /molecular_weight="3183.6"
                     /monoisotopic_mass="3181.6"
                     /core_sequence="GTVEGQSLISPASIAFCLTPLPVSTMSAAFCNN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSRGKQISNILKLQSLESGPVYTAGAT"
                     /leader_location="[3988:4069](+)"
                     /alternative_weights="3201.7"
                     /alternative_weights="3219.7"
                     /alternative_weights="3237.7"
                     /alternative_weights="3255.7"
                     /alternative_weights="3273.7"
                     /alternative_weights="3291.8"
     CDS             4193..5749
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 73.3;
                     E-value: 3.8e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg9_7"
                     /sec_met_domain="Pkinase (E-value: 5.8e-17, bitscore: 50.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYFKYFISTNNSFYTKPDTPNRESALYISNIPNNYKTIRENH
                     WIHVINKEHKLPMQGWKIHISTTIDSAEKTLEIVSNVLFDYKISFKYVKSLWELSIKNS
                     KYSNRSAAGKFITIFPPNEQVFLNLLEILSSLLDTLPRGPYILTDKRWYESNVYFRYGA
                     FLSMYYYENNKKVFAIQSPSGDLVEDSRSPHYSIPKFITEPAPIREMDNKLENEIAEPT
                     PLDDIEVIHAIHYSNGGGVYLALDKLDKKVILKEGRPNIGLDSLGIDAFTRIKNEAMIL
                     KKLEGTRYPVKIYDFFKAWEHNFILEEYIEGTSLRTWLATKYPFYTNETNKEYLKTVLK
                     ILNQLIDALTEIHNQGIGIGDLQPSNIIITSDENIRLIDFETASFIDDSVPSGLKTFGF
                     TGGPNMTRKQADWFALLRISRYLFLPIGPVQDISSKILEAHDKYIENYFGIEAIKIINK
                     IQKICSQVQANPAKDLLNVEHNHIKEMSLNEVKMLLQNNIINNLFVDERVIPGDIRQYE
                     LE"
ORIGIN
        1 ccattgtaat atttcccata gggtattaca atataaataa cttaaattgc ctaaaaaaga
       61 aaaaaaagaa atagaaaggt aatgagtcat ggataatata tgtaaactta gttttcaatt
      121 aggaaaatca aaagtgaatt cattaggtag cgcatctatt atcatataca aagatgaatt
      181 ctttgttgct actgcagctc attgcctata cgatgtaggc agtaatgaaa tagctaaaaa
      241 catatcaata gaagtagaga actgtggaat gaaagaatca tatgatgtac taaatatagt
      301 aatacctgaa aaatggatta gtactcatag gttaacttat gactatgctt ttggatggat
      361 taaattgcct gaaagcatga ggaatgttgc ttttattcct aactttgatt taagtgggat
      421 gatagaagag cataataaag cggttacatt agcaggctac ccaatttcat tttttaaatc
      481 tcagaagaaa tactctaaag gagatttaga tttaactctt tttaaagaag agcagcttat
      541 tggaatgaga tccaaactta aacatgggat atctggcggt ccttggtttt ttgaaagtga
      601 taatgaaaaa ttccagattg gtgttacatc tgcaagaatt aaaagtttca aaaataaggt
      661 ttgggcgtct atttggacta aagatacaga aagaatacta aacaagttat tgacaagtga
      721 gatgcaagaa aaaattattc tagcctaaag tgagggattt tgatggattt aagatatgtt
      781 gagtttttga gcccaggcaa tttattttat gaattggtaa caccgaataa aatagtaaac
      841 aattatcgta tcccaaactt aaattctgaa gagtggaaac aaaacacgga tattaattgg
      901 agttattgta ttaacacaaa gaaaaagatg cccaaacaag gatggaaaat acatatcact
      961 acagatattg atgaggcaca aaagacttta gatattgtcc ttccatatct cattgaaaat
     1021 gaaatatcct ttaaatttgt tcctaatgaa aggcaattat tattcaaaaa ctctaaaaac
     1081 ggagacagag catcttcggg taaattcatt acaatctatc cttacgataa caagactttt
     1141 ctaacattac tttcagattt agataatctg actaaagctt taaaaaaagg tccttatata
     1201 ttgaatgata aacgctggaa gtattcaaat gtcttctttc gttatggagc atttgtatct
     1261 atgtatgtga ataaagatgg acaaaatgtt ccagcaattc agcgacctga tggcacatta
     1321 attccagatg tccgtgctcc atattatgaa gttcctgact ttgttgaaga acctgttgaa
     1381 atacaaatca tgactaaaaa agttgatgca gaacttgata aagaagacac atcgaagttt
     1441 gattcataca atgttatttc tgcactgcat tttagcaatg gtggtggagt atataaagtt
     1501 gaaaaaaacg ggaaaacgtt tgttatgaaa gaaggaagac ttggttcagg tttggatcgg
     1561 ttgaaactag atggttttaa acgaatttat aaagaggctg aaacaataaa gcaattaagt
     1621 gagaagcctt acatagttga tttttacgat tactttgaga tttgggaaaa taactatttg
     1681 attgaagaac atgtatcagg aatttctctt atggaatatg tatctcaaaa ctttccgttt
     1741 tcatataaag aagataaaga tatttatatg gaacgcatga tgcatgtgat agatcagttg
     1801 attgatgctt taaaagatct tcatagaagt aagattgcac tcggagattt acagccaaat
     1861 aatgtattgg tattagagga ttactcaatc aaattaatag acctagaaac tgctgtaact
     1921 cccgaaagca aatacacccc cgccttaatg actcctggtt acgttacgga tcaagcagaa
     1981 acttttgagc aagcagattg gtatgcatta cttagaattt gcaggttttt atttttaccg
     2041 atagaaaatt tatctgatct gtcaattgat attgaaataa atcaagataa atggattgga
     2101 gagaattttg gggatgcagt tttaaataaa attcaagaaa ttcaagagaa gacattacca
     2161 accatcaaga aattaagtga agctgctact ttaacaattc caccaatgaa aataaactac
     2221 aagaatgtta atgagataac tgaaggtttg cgagctggaa ttatgagtca tttaaaacct
     2281 aagtcagaaa gtttaatatc cggagatatc aggcaattca ttgaaaaaat gggcagtcta
     2341 tcaatcgcta atggaggatt tggtggaata atggccttgg atagaacagg gactctatcc
     2401 gattcagttt atcaatgggt tgatcatgta ttggagacaa tattgaattt agacacggaa
     2461 acatataaaa atttcccgct cggtttattt aatggtatct caggcatatt gtccgtttta
     2521 tacgatattg gatataaaga agaagcaatt aaactgttag agacaatgcc tttgccagat
     2581 actgaagatt cagatttaac actgttttcc ggattatcgg gaattggatt aaactacctt
     2641 gccttttata gcattactca gaaaaaaggc tttctagatc gctctataaa aataggaaat
     2701 agaataatag atgcctataa agaagactgc tccatcactg taagggatcc ttatgcaatg
     2761 ccgtatggct tgttaaatgg ctggtctgga atcagcttgt atattctaat gttaggcaag
     2821 gcgacaaatg acaatgactt aataaagctg gctagcgaaa ttttcaataa agaaataagc
     2881 aaaaacattg aaattgattc taaattagaa ttagcacaaa taaaagaata ttcattgggc
     2941 tataaaaggt tgataccata tcttggtgaa ggtgcagctg ggattgcatt aattatgctt
     3001 gaattcaata aaaatcttcc tgattttatg acagaaagta atactgaact attcaaaaaa
     3061 ctaactaatg ttacagactt atatagcaca tttgcaagtg gcatctttcg aggtgtggga
     3121 ggaatgatta ttcttgcgaa tgcaatgaaa tgtgaagggg taaatacagg ctcattagaa
     3181 tataccatta aagcactcgg gaattatctc ctgtataaga aacaagaagg aattttaagt
     3241 ccaggagagt atggttaccg actatcttta gacttacaaa caggaaacag cgggttacta
     3301 cttgctcttt ctgatataga tagtgataaa tggaatagtt ggttaccgtt acctaaaaac
     3361 aataatctga atctctttga aatagacaag ttcattaaag gaggtgaaac aaatgaaaaa
     3421 gctattatct cttcagcaca aagcacttga taaagaggtt actctattaa aaggcaagtc
     3481 atcagtaagc ttaggctgcg ataagatcag tacagttagt ttgtatttct gcggtaacta
     3541 agattactca ctgtttagac taaaggaggt gaaacaaatg aaaaagctat tatctcttca
     3601 gcacaaagca cttgataaag aggttactct attaaaaggt agatcatcag taagcttagg
     3661 ctgcgataag atcagtacag taagtttgta tttctgcggt aactaaagat tactcactgt
     3721 ttagactaaa ggaggtaaaa caaatgaaaa agttattatc acttcagcat aaagcgcttg
     3781 ataaagaggt tactctatta aaaggcaaat catcagtaag cttaggctgc gataagatca
     3841 gtacagttag tttgtatttc tgtggtaact aatgattatg gacaacccta cttaaagaaa
     3901 agagagggga tcatcctctc ttttctttgt attacccaaa aagtaaatac aataaactat
     3961 ttaaaaaata taaaaggagt tggatgaaat gtcaagagga aagcaaatca gtaatatcct
     4021 gaaattgcag agcttagaaa gtggtccagt atatactgca ggagcgacag gaactgttga
     4081 aggtcaatca cttatttcac ctgctagtat agctttttgt ttaactcctc ttcctgtcag
     4141 taccatgagt gcagcttttt gcaataacta atctcttgag agggttgtaa atatggactt
     4201 acgatacttc aaatacttta tctcgacaaa caattctttt tatacaaagc ccgatacccc
     4261 taacagggaa tcggctttgt atatttctaa tatacctaat aattataaaa ccataagaga
     4321 aaatcattgg attcatgtta taaacaaaga gcataaactt ccaatgcaag gttggaagat
     4381 acatataagt actacaatag attctgcaga aaaaacatta gaaattgtat caaatgtcct
     4441 attcgattac aaaatctctt ttaaatacgt taaaagctta tgggaattaa gtattaaaaa
     4501 ttcaaaatac agcaataggt ctgctgcggg taagtttatt acaattttcc cgccaaatga
     4561 acaagtattt ttaaatttgt tagaaatatt aagcagtctg ctagatactc ttcctagagg
     4621 cccttatatt ttaactgata aaagatggta cgaaagtaat gtatatttta gatatggtgc
     4681 atttttaagt atgtattatt atgaaaataa taaaaaggta tttgctattc aaagtccttc
     4741 tggtgactta gttgaagact caagaagtcc tcattattct atacccaaat ttatcactga
     4801 acctgctcca ataagagaga tggataataa attagaaaac gaaatagctg aacctactcc
     4861 attagatgat atagaggtta tccatgcaat tcattatagt aatggagggg gagtctactt
     4921 agccctagat aaactagaca aaaaagttat ccttaaggaa ggaaggccaa acattggatt
     4981 agatagtctg ggaattgatg cctttacaag aataaaaaat gaagcgatga ttttaaaaaa
     5041 acttgaagga acgcgttacc ctgtaaaaat atatgatttt tttaaggcgt gggaacataa
     5101 ttttatttta gaggaatata ttgaaggcac atcactgaga acttggcttg caacaaaata
     5161 tcctttttat acgaatgaaa caaataaaga atacttaaaa acagtattaa aaattttgaa
     5221 tcaattaata gatgctctaa ctgaaataca taatcaagga atagggatag gagacttaca
     5281 gccctcaaat attattatca catcagacga aaatatacga ttgatcgact ttgagactgc
     5341 aagttttatt gatgatagtg taccatcggg tttaaaaaca tttggtttta ctggcgggcc
     5401 taatatgacg agaaaacaag cggattggtt tgcgttacta agaatatcga gatatttatt
     5461 tttacctatc ggaccagttc aagatatttc ttcaaaaatt ttagaggcac atgataaata
     5521 tattgaaaat tattttggca tcgaagctat aaaaataatt aataaaatac aaaaaatttg
     5581 ttctcaagtt caggcaaatc cagctaaaga tttattgaat gttgaacata accatattaa
     5641 agaaatgtca ctaaatgaag taaagatgtt acttcaaaat aatataataa ataatttgtt
     5701 tgttgatgaa agggtaatcc caggagatat tagacagtat gaattagaa
//
