GCA_019997305.2 - 22 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaOHOOHJJF_1 (original name was: gnl|Prokka|OHOOHJJF_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS	23,993	89,403	surfactin	NRP:Lipopeptide	82%

gnlProkkaOHOOHJJF_6 (original name was: gnl|Prokka|OHOOHJJF_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	lanthipeptide-class-i	1	7,509	entianin	RiPP:Lanthipeptide	45%

gnlProkkaOHOOHJJF_10 (original name was: gnl|Prokka|OHOOHJJF_10)

Region	Type	From	To	Most similar known cluster		Similarity
Region 10.1	NRPS	1	6,752

gnlProkkaOHOOHJJF_15 (original name was: gnl|Prokka|OHOOHJJF_15)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	terpene	1	6,562

gnlProkkaOHOOHJJF_42 (original name was: gnl|Prokka|OHOOHJJF_42)

Region	Type	From	To	Most similar known cluster		Similarity
Region 42.1	NRPS	1	3,708

gnlProkkaOHOOHJJF_54 (original name was: gnl|Prokka|OHOOHJJF_54)

Region	Type	From	To	Most similar known cluster		Similarity
Region 54.1	NRPS-like	1	2,868

gnlProkkaOHOOHJJF_79 (original name was: gnl|Prokka|OHOOHJJF_79)

Region	Type	From	To	Most similar known cluster		Similarity
Region 79.1	transAT-PKS-like	23,114	69,018	difficidin	Polyketide	53%

gnlProkkaOHOOHJJF_173 (original name was: gnl|Prokka|OHOOHJJF_173)

Region	Type	From	To	Most similar known cluster		Similarity
Region 125.1	transAT-PKS	1	53,656	macrolactin H/macrolactin B/macrolactin 1c/macrolactin E	Polyketide	100%

gnlProkkaOHOOHJJF_182 (original name was: gnl|Prokka|OHOOHJJF_182)

Region	Type	From	To	Most similar known cluster		Similarity
Region 128.1	PKS-like	1	25,161	butirosin A/butirosin B	Saccharide	7%

gnlProkkaOHOOHJJF_183 (original name was: gnl|Prokka|OHOOHJJF_183)

Region	Type	From	To	Most similar known cluster		Similarity
Region 129.1	other	5,966	47,384	bacilysin	Other	100%

gnlProkkaOHOOHJJF_184 (original name was: gnl|Prokka|OHOOHJJF_184)

Region	Type	From	To	Most similar known cluster		Similarity
Region 130.1	NRPS,transAT-PKS	1	46,552	bacillomycin D	Polyketide+NRP:Lipopeptide	60%

gnlProkkaOHOOHJJF_203 (original name was: gnl|Prokka|OHOOHJJF_203)

Region	Type	From	To	Most similar known cluster		Similarity
Region 149.1	transAT-PKS,NRPS	1	33,505

gnlProkkaOHOOHJJF_206 (original name was: gnl|Prokka|OHOOHJJF_206)

Region	Type	From	To	Most similar known cluster		Similarity
Region 152.1	NRPS,NRP-metallophore	1	30,555	bacillibactin	NRP	100%

gnlProkkaOHOOHJJF_207 (original name was: gnl|Prokka|OHOOHJJF_207)

Region	Type	From	To	Most similar known cluster		Similarity
Region 153.1	NRPS,betalactone	2,602	30,211	fengycin	NRP	73%

gnlProkkaOHOOHJJF_210 (original name was: gnl|Prokka|OHOOHJJF_210)

Region	Type	From	To	Most similar known cluster		Similarity
Region 156.1	transAT-PKS-like	1	23,214	difficidin	Polyketide	26%

gnlProkkaOHOOHJJF_214 (original name was: gnl|Prokka|OHOOHJJF_214)

Region	Type	From	To	Most similar known cluster		Similarity
Region 160.1	NRPS	1	21,521

gnlProkkaOHOOHJJF_227 (original name was: gnl|Prokka|OHOOHJJF_227)

Region	Type	From	To	Most similar known cluster		Similarity
Region 173.1	transAT-PKS,NRPS,T3PKS	1	91,820	bacillaene	Polyketide+NRP	100%

gnlProkkaOHOOHJJF_231 (original name was: gnl|Prokka|OHOOHJJF_231)

Region	Type	From	To	Most similar known cluster		Similarity
Region 177.1	NRPS	1	15,139	plipastatin	NRP	23%

gnlProkkaOHOOHJJF_232 (original name was: gnl|Prokka|OHOOHJJF_232)

Region	Type	From	To	Most similar known cluster		Similarity
Region 178.1	T3PKS	1	14,956

gnlProkkaOHOOHJJF_234 (original name was: gnl|Prokka|OHOOHJJF_234)

Region	Type	From	To	Most similar known cluster		Similarity
Region 180.1	transAT-PKS	1	14,753	difficidin	Polyketide	46%

gnlProkkaOHOOHJJF_238 (original name was: gnl|Prokka|OHOOHJJF_238)

Region	Type	From	To	Most similar known cluster		Similarity
Region 184.1	terpene	60,713	81,453

gnlProkkaOHOOHJJF_253 (original name was: gnl|Prokka|OHOOHJJF_253)

Region	Type	From	To	Most similar known cluster		Similarity
Region 199.1	NRPS	1	9,379	fengycin	NRP	13%

Compact view

gnlProkkaOHOOHJJF_1 - Region 1 - NRPS

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Location: 23,993 - 89,403 nt. (total: 65,411 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 23992 - 89403:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Glu - Leu - D-Leu) + (Val - Asp - D-Leu) + (Leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg1_40

Search NORINE for peptide: strict or relaxed

AMP-binding (465..867): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code(s):: Glu DAKDLGVVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1511..1908): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code(s):: Leu DAFMMGMVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2550..2940): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code(s):: Leu DAWFLGNVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg1_41

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code(s):: Val DAFWIGGTFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1502..1904): Asp

nrpys: Asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asp (Asp)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code(s):: Asp DLTKVGHIGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2547..2936): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code(s):: Leu DAWFLGNVVK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg1_42

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code(s):: Leu DAFFLGCVFK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_6 - Region 1 - lanthipeptide-class-i

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Location: 1 - 7,509 nt. (total: 7,509 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

Lanthipeptide predictions

Lanthipeptide(s) for ctg6_6

allorf_1904_2083

Leader:

MTNMSKFDDFDLDVVKVSKQDSKITPQ

Core:

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

Core with dehydrations:

VLDhaKDhaLCysDhbPGCysIDhbGPLQDhbCysFLQDhbIDhbCysNCysHIDhaK

MIBiG 3.1 matches for allorf_1904_2083

55.9% BGC0000535 (ADJ56352.1): Lanthipeptide: nisin A

1

VLSKSLCTPGCITGPLQTCFLQTITCNC--HISK

32

+ S SLCTPGC TG L C ++T TC+C H+SK

1

ITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK

34

antiSMASH-DB 4.0 matches for allorf_1904_2083

81.2% NZ_CP021903.1and 20 others:

NZ_CP023409.1 Lanthipeptides: Bateq7PJ16_RS18530_lanthipeptideNZ_CP026036.1 Lanthipeptides: C2H93_RS15000_lanthipeptideNZ_CP028218.1 Lanthipeptides: C7M30_RS14555_lanthipeptideNZ_CP035167.1 Lanthipeptides: EQJ08_RS17140_lanthipeptideNZ_CP035226.1 Lanthipeptides: EQW70_RS18175_lanthipeptideNZ_CP045006.1 Lanthipeptides: F9B13_RS03875_lanthipeptideNZ_CP076083.1 Lanthipeptides: KFF76_RS16710_lanthipeptideNZ_CP079759.1 Lanthipeptides: KXZ66_RS17780_lanthipeptideNZ_CP080508.1 Lanthipeptides: K0V03_RS06525_lanthipeptideNZ_CP089148.1 Lanthipeptides: LRO88_RS19055_lanthipeptideNZ_JALAUA010000003.1 Lanthipeptides: MOD32_RS04985_lanthipeptideNZ_JALAVX010000009.1 Lanthipeptides: MOE40_RS09385_lanthipeptideNZ_JAMYDW010000007.1 Lanthipeptides: NHM07_RS16180_lanthipeptideNZ_JAQOXM010000001.1 Lanthipeptides: PO770_RS03875_lanthipeptideNZ_NJRD01000003.1 Lanthipeptides: CE053_RS07200_lanthipeptideNZ_NJRE01000008.1 Lanthipeptides: CE047_RS18435_lanthipeptideNZ_SORJ01000001.1 Lanthipeptides: BJ795_RS01490_lanthipeptideNZ_VFNF01000001.1 Lanthipeptides: FB592_RS01525_lanthipeptideNZ_VIOH01000001.1 Lanthipeptides: FLN47_RS03850_lanthipeptideNZ_VLJL01000012.1 Lanthipeptides: L604_RS09425_lanthipeptide

Lanthipeptides: CD007_RS17065_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHISK

32

S+SLCTPGC+TG LQTCFLQTITCNC ISK

3

SESLCTPGCVTGVLQTCFLQTITCNCKISK

32

81.2% NZ_CP025079.1and 3 others:

NZ_CP047644.1 Lanthipeptides: GNE05_RS17275_lanthipeptideNZ_CP099859.1 Lanthipeptides: NIZ95_RS16280_lanthipeptideNZ_CP101621.1 Lanthipeptides: NN913_RS16115_lanthipeptide

Lanthipeptides: BVQ_RS17705_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHISK

32

S+S+CTPGC+TG LQTCFLQTITCNCHISK

3

SESVCTPGCVTGVLQTCFLQTITCNCHISK

32

78.1% NC_014479.1and 9 others:

NZ_CP026362.1 Lanthipeptides: BV11031_RS00400_lanthipeptideNZ_CP033052.1 Lanthipeptides: D9779_RS17315_lanthipeptideNZ_CP051464.1 Lanthipeptides: HC660_RS17030_lanthipeptideNZ_JALAKK010000002.1 Lanthipeptides: MOB09_RS02800_lanthipeptideNZ_JALAKO010000014.1 Lanthipeptides: MOB26_RS08535_lanthipeptideNZ_JALAOG010000003.1 Lanthipeptides: MOC96_RS02500_lanthipeptideNZ_JALAPG010000043.1 Lanthipeptides: MOC70_RS16815_lanthipeptideNZ_JALAQI010000009.1 Lanthipeptides: MOD13_RS06065_lanthipeptideNZ_NXEM01000027.1 Lanthipeptides: CPT06_RS15285_lanthipeptide

Lanthipeptides: BSUW23_RS16845_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHISK

32

S+SLCTPGC+TG LQTCFLQT+TCNC ISK

3

SESLCTPGCVTGALQTCFLQTLTCNCKISK

32

with 96 more sequence matches

78.1% NC_016047.1and 2 others:

NZ_KZ848487.1 Lanthipeptides: DSL71_RS15965_lanthipeptideNZ_MUXL01000003.1 Lanthipeptides: B0W20_RS12275_lanthipeptide

Lanthipeptides: GYO_RS39160_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHISK

32

S+S+CTPGC+TG LQTCFLQTITCNC ISK

3

SESVCTPGCVTGLLQTCFLQTITCNCKISK

32

78.1% NZ_BMMB01000002.1: Lanthipeptides: IEX62_RS05935_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHISK

32

SKS CTPGC+TG LQTCF+QT TCNCHISK

3

SKSFCTPGCVTGVLQTCFIQTATCNCHISK

32

75.0% NZ_CP117416.1and 1 other:

NZ_JAQQZQ010000001.1 Lanthipeptides: PO903_RS06885_lanthipeptide

Lanthipeptides: PQ456_RS01230_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHISK

32

S+S CTPGC+TG LQTCF+QT TCNCHISK

3

SQSFCTPGCVTGVLQTCFIQTATCNCHISK

32

65.6% NZ_AUAQ01000012.1: Lanthipeptides: G393_RS16160_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHISK

32

SKSLCTPGCITG LQTC +Q+ TC H+S+

3

SKSLCTPGCITGILQTCAIQSFTCEVHVSR

32

62.5% NC_015600.1and 14 others:

NZ_AP020310.1 Lanthipeptides: SAGCMC97051_RS07300_lanthipeptideNZ_ATVP01000001.1 Lanthipeptides: G574_RS11150_lanthipeptideNZ_BCFB01000042.1 Lanthipeptides: GOZ36_RS07980_lanthipeptideNZ_CP068708.1 Lanthipeptides: JM964_RS04040_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_FIKS01000005.1 Lanthipeptides: A0525_RS10015_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS106200_lanthipeptideNZ_JADPLU010000018.1 Lanthipeptides: I4V82_RS09545_lanthipeptideNZ_JAKVIE010000017.1 Lanthipeptides: MK857_RS08340_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_LR594050.1 Lanthipeptides: FGL20_RS03485_lanthipeptideNZ_SSXN01000004.1 Lanthipeptides: FAJ36_RS04715_lanthipeptide

Lanthipeptides: SGPB_RS10680_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

V SKSLCTPGC TG L TC ++T TC CH

1

VTSKSLCTPGCKTGILMTCAIKTATCGCHFG

31

62.5% NZ_CP025079.1and 2 others:

NZ_CP047644.1 Lanthipeptides: GNE05_RS17285_lanthipeptideNZ_CP099859.1 Lanthipeptides: NIZ95_RS16290_lanthipeptide

Lanthipeptides: BVQ_RS17715_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFL

21

VLSKSLCTPGCITGPLQTC+L

1

VLSKSLCTPGCITGPLQTCYL

21

62.5% NZ_JAMDIB010000004.1: Lanthipeptides: M5P35_RS04030_lanthipeptide

1

VLSKSLCTP-GCITGPLQTCFLQTITCNCHIS

31

V SKSLCTP GC TG L TC ++T TC CH

1

VTSKSLCTPPGCKTGILMTCAIKTATCGCHFG

32

61.1% NZ_NHVL01000013.1: Lanthipeptides: CEU70_RS16825_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNC--HISK

32

V SKSLCTPGC TG LQTC +++ TC C HI K

3

VTSKSLCTPGCKTGILQTCAIKSATCGCSIHIGK

36

60.6% NZ_CP015405.2and 7 others:

NZ_CP015405.2 Lanthipeptides: A4V09_RS08295_lanthipeptideNZ_CP015405.2 Lanthipeptides: A4V09_RS08290_lanthipeptideNZ_CP015405.2 Lanthipeptides: A4V09_RS08285_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06240_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06235_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06230_lanthipeptideNZ_CP053228.1 Lanthipeptides: HL650_RS06225_lanthipeptide

Lanthipeptides: A4V09_RS08300_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

+ SKSLCTPGC+TG L TC +QT TC C I+

1

ITSKSLCTPGCVTGILMTCPVQTATCGCQIT

31

60.6% NZ_JADNJR010000016.1and 2 others:

NZ_JADNJR010000016.1 Lanthipeptides: I2E58_RS10875_lanthipeptideNZ_QSHK01000002.1 Lanthipeptides: DW860_RS04740_lanthipeptide

Lanthipeptides: I2E58_RS10880_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHIS

31

SKS CTPGC TG L TC L+T TC CHI+

3

SKSACTPGCPTGILMTCPLKTATCGCHIT

31

60.6% NZ_QSHK01000002.1and 1 other:

NZ_QSHK01000002.1 Lanthipeptides: DW860_RS04730_lanthipeptide

Lanthipeptides: DW860_RS04735_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTITCNCHIS

31

SKS+CTPGC TG L TC L+T TC CHI+

3

SKSVCTPGCPTGILMTCPLKTATCGCHIT

31

59.4% NZ_CP024974.1and 1 other:

NZ_JAIMDQ010000006.1 Lanthipeptides: K6V44_RS04045_lanthipeptide

Lanthipeptides: CVO91_RS06555_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

V S SLCTPGC TG L TC ++T TC CH

1

VTSISLCTPGCKTGILMTCAIKTATCGCHF

30

59.4% NZ_CP059471.1and 3 others:

NZ_FNZW01000001.1 Lanthipeptides: BMZ61_RS02110_lanthipeptideNZ_FOYC01000001.1 Lanthipeptides: BMZ88_RS03370_lanthipeptideNZ_KE384124.1 Lanthipeptides: G597_RS0106700_lanthipeptide

Lanthipeptides: H1R75_RS06635_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

32

+ SKSLCTPGC TG L TC ++T TC CH

1

ITSKSLCTPGCKTGALMTCPIKTATCGCHFGN

32

58.8% NC_013656.1and 18 others:

NC_020450.1 Lanthipeptides: LILO_RS03015_lanthipeptideNZ_CP009472.1 Lanthipeptides: LG36_RS03420_lanthipeptideNZ_CP010050.1 Lanthipeptides: QI18_RS03300_lanthipeptideNZ_CP015903.1 Lanthipeptides: LLUC08_RS03255_lanthipeptideNZ_CP024954.1 Lanthipeptides: CV702_RS02990_lanthipeptideNZ_CP066300.1 Lanthipeptides: LacL0098_RS03205_lanthipeptideNZ_CP098790.1 Lanthipeptides: M5C73_RS03405_lanthipeptideNZ_JAALEQ010000006.1 Lanthipeptides: HFD15_RS10120_lanthipeptideNZ_JAJONJ010000005.1 Lanthipeptides: LSG16_RS07195_lanthipeptideNZ_JAQDWM010000007.1 Lanthipeptides: PGU01_RS08180_lanthipeptideNZ_JAQDXV010000018.1 Lanthipeptides: PGT80_RS11850_lanthipeptideNZ_JAQEIZ010000019.1 Lanthipeptides: PGX18_RS12025_lanthipeptideNZ_JAQEOU010000022.1 Lanthipeptides: PGV42_RS12330_lanthipeptideNZ_JAQEOV010000015.1 Lanthipeptides: PGW09_RS10765_lanthipeptideNZ_MTJP01000006.1 Lanthipeptides: BW151_RS03795_lanthipeptideNZ_MTJR01000005.1 Lanthipeptides: BW153_RS02980_lanthipeptideNZ_MTJS01000002.1 Lanthipeptides: BW154_RS09850_lanthipeptideNZ_RAGL01000022.1 Lanthipeptides: D6108_RS11395_lanthipeptide

Lanthipeptides: LLKF_RS13210_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNC--HISK

32

+ S SLCTPGC TG L C ++T TCNC H+SK

1

ITSISLCTPGCKTGALMGCNMKTATCNCSIHVSK

34

57.1% NZ_CP013655.1and 2 others:

NZ_CP013655.1 Lanthipeptides: ATZ35_RS03635_lanthipeptideNZ_CP013655.1 Lanthipeptides: ATZ35_RS03630_lanthipeptide

Lanthipeptides: ATZ35_RS03640_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

+ SKSLCTPGC+TG L C L+TITCNC +

1

ITSKSLCTPGCVTGVLMGCALKTITCNCSVG

31

55.9% NC_022237.1and 1 other:

NZ_JUZI01000019.1 Lanthipeptides: ADI02_RS09325_lanthipeptide

Lanthipeptides: SII_RS05025_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

V S +CTPGC+TG L C LQT TCNCH+

1

VTSVFMCTPGCVTGALMGCNLQTATCNCHV

30

55.9% NZ_CP065984.1and 2 others:

NZ_CP095737.1 Lanthipeptides: MXM90_RS03205_lanthipeptideNZ_JAQDXJ010000021.1 Lanthipeptides: PGU19_RS11740_lanthipeptide

Lanthipeptides: I6I21_RS02785_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNC--HISK

32

+ S SLCTPGC TG L C ++T TC+C H+SK

1

ITSISLCTPGCKTGALMGCNMKTATCHCSIHVSK

34

55.9% NZ_JADNFO010000025.1: Lanthipeptides: I2C89_RS09745_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ S SLCTPGC TG L C L+T TCNC I

1

ITSYSLCTPGCKTGVLMACHLKTATCNCSI

30

55.9% NZ_JAQDYA010000007.1and 1 other:

NZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptide

Lanthipeptides: PGT72_RS09560_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNC--HISK

32

+ S SLCTPGC TG L C ++T TCNC H+S+

1

ITSISLCTPGCKTGALMGCNMKTATCNCSIHVSR

34

54.5% NC_009328.1and 6 others:

NZ_CP014140.1 Lanthipeptides: ACH33_RS18880_lanthipeptideNZ_CP014749.1 Lanthipeptides: A0V43_RS19510_lanthipeptideNZ_CP014749.1 Lanthipeptides: A0V43_RS19510_lanthipeptideNZ_CP017690.1 Lanthipeptides: GTID1_RS08690_lanthipeptideNZ_CP017694.1 Lanthipeptides: GD3902_RS07590_lanthipeptideNZ_PIJH01000004.1 Lanthipeptides: CV632_RS11810_lanthipeptide

Lanthipeptides: GTNG_RS18005_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQT--ITCN

27

V SKSLCTPGCITG L C Q ++CN

1

VTSKSLCTPGCITGVLM-CLTQNSCVSCN

28

54.5% NZ_CP023704.1: Lanthipeptides: CQJ30_RS18315_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQT--ITCN

27

V SKSLCTPGCITG L C Q ++CN

1

VTSKSLCTPGCITGILM-CLTQNSCVSCN

28

53.1% NZ_CP101621.1: Lanthipeptides: NN913_RS16125_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFL

21

V+SKSLCTPGCITG L+TC L

1

VVSKSLCTPGCITGALRTCTL

21

52.9% NZ_CP009913.1and 1 other:

NZ_CP009913.1 Lanthipeptides: SSAL8618_RS00810_lanthipeptide

Lanthipeptides: SSAL8618_RS00815_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ S SLCTPGCITG L C +Q+I CN H+

1

ITSYSLCTPGCITGVLMGCHIQSIGCNVHV

30

51.5% NC_006510.1and 4 others:

NZ_CP018058.1 Lanthipeptides: GT3921_RS18655_lanthipeptideNZ_CP025074.1 Lanthipeptides: CWI35_RS08795_lanthipeptideNZ_CP027303.2 Lanthipeptides: C1N76_RS05790_lanthipeptideNZ_CP038860.1 Lanthipeptides: E5Z46_RS04660_lanthipeptide

Lanthipeptides: GK_RS18085_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQT--ITCN

27

+ SKSLCTPGCITG L C Q ++CN

1

ITSKSLCTPGCITGILM-CLTQNSCVSCN

28

51.4% NZ_CP113114.1and 1 other:

NZ_FZDV01000015.1 Lanthipeptides: CFW84_RS08635_lanthipeptide

Lanthipeptides: OTU45_RS07045_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

+ S SLCTPGC+TG L C TI+CN H S

1

ITSVSLCTPGCVTGVLM-CPGNTISCNGHCS

30

51.4% NZ_FNDP01000013.1: Lanthipeptides: BLP54_RS11230_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ SKSLCTPGC+TG L C +T TCNC +

3

ITSKSLCTPGCVTGVLMGCNNKTATCNCSV

32

50.0% NZ_CP086322.1: Lanthipeptides: K9S39_RS23570_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

32

+ S SLCTPGC+T C T CHISK

1

ITSVSLCTPGCVTAA--GCTTAKCTQGCHISK

30

50.0% NZ_CP116604.1and 2 others:

NZ_JAFFHI010000008.1 Lanthipeptides: JN541_RS08535_lanthipeptideNZ_JAFFHJ010000004.1 Lanthipeptides: JN542_RS06245_lanthipeptide

Lanthipeptides: PHA78_RS04905_lanthipeptide

1

VLSKSLCTPGCITGPLQTCF-LQTITCNCH

29

+ S SLCT GCITG + C T++CNCH

1

ITSISLCTAGCITGRIMGCHKTPTVSCNCH

30

50.0% NZ_LR793265.1: Lanthipeptides: HV392_RS09825_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ S SLCTPGCITG L C Q+ CN H+

1

ITSYSLCTPGCITGRLMGCQFQSAGCNVHV

30

50.0% NZ_LR793265.1: Lanthipeptides: HV392_RS09830_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ S SLCTPGCITG L C Q+ CN H+

1

ITSYSLCTPGCITGVLMGCQFQSAGCNVHV

30

50.0% NZ_NHVL01000013.1: Lanthipeptides: CEU70_RS16830_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

V SKSLCTPGC TG LQTC +++ TC C I

3

VTSKSLCTPGCKTGILQTCAIKSATCGCSI

32

48.6% NZ_FNDP01000013.1and 1 other:

NZ_FNDP01000013.1 Lanthipeptides: BLP54_RS11225_lanthipeptide

Lanthipeptides: BLP54_RS11220_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ SKSLCTPGC+TG L C + TCNC +

3

ITSKSLCTPGCVTGLLMGCAGSSATCNCSV

32

48.6% NZ_JALDTZ010000003.1: Lanthipeptides: M1F37_RS03135_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

+ S+S CTPGC+TG L C TI+CN H S

1

ITSRSFCTPGCVTGILM-CPGNTISCNGHCS

30

47.1% NZ_CP090412.1and 3 others:

NZ_QSTB01000004.1 Lanthipeptides: DXC22_RS03785_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide

Lanthipeptides: LZF92_RS09890_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ S SLCTPGC TG L C ++T +C CH+

1

ITSYSLCTPGCKTGALMGCTMKTASCGCHV

30

47.1% NZ_FBTD01000003.1: Lanthipeptides: PB1E_RS03075_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHI

30

+ S SLCTPGC TG L C ++T +C CH+

1

ITSVSLCTPGCKTGALMGCNMKTASCGCHV

30

47.1% NZ_JALGRO010000002.1: Lanthipeptides: MT346_RS01980_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

32

+ S SLCTPGC TG CF T C IS

1

ITSFSLCTPGCPTGGFA-CFTAACTGGCTISS

31

47.1% NZ_KE951497.1: Lanthipeptides: allorf_8519_8683_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

+ SK LCTPGC TG + CF T C IS

1

ITSKFLCTPGCPTGGIA-CFTTQCTNGCSIS

30

47.1% NZ_SNVW01000005.1: Lanthipeptides: EDF64_RS09155_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

32

+ S SLCTPGC TG CF T C IS

1

ITSVSLCTPGCPTGGFA-CFTAACTGGCTISS

31

46.9% NZ_AULX01000006.1and 1 other:

NZ_LT732548.1 Lanthipeptides: CZ379_RS19505_lanthipeptide

Lanthipeptides: H583_RS0100280_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQ

22

+ SKSLCTPGCITG L CF +

1

ITSKSLCTPGCITGVLM-CFTK

21

46.9% NZ_CP034587.1: Lanthipeptides: EKH77_RS16870_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

32

+ S SLCTPGC + C T CHISK

1

ITSISLCTPGCPSA--AGCTTSVCTQGCHISK

30

46.9% NZ_CP113914.1: Lanthipeptides: allorf_1411802_1411978_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

V S SLCTPGC +G CF T CH

1

VTSHSLCTPGCPSGGF-ACFSTQCTNGCHFG

30

46.9% NZ_NDXL01000003.1: Lanthipeptides: B7024_RS31125_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

32

+ S SLCTPGC+T C T CH+SK

1

ITSWSLCTPGCVTAA--GCTTSVCTQGCHVSK

30

46.2% NZ_AP019008.1and 1 other:

NZ_BDDX01000012.1 Lanthipeptides: FF306_RS05510_lanthipeptide

Lanthipeptides: FF306_RS00060_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHISK

32

+ S LCTPGCITG L C +T TC+CH S

1

ITSYVLCTPGCITGRLMGCNNKTKTCHCHSSN

32

46.2% NZ_JXCW01000008.1: Lanthipeptides: RZ55_RS07215_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCNCHIS

31

+ S LCTPGCITG L C +T TC+CH S

1

ITSYVLCTPGCITGRLMGCNNKTKTCHCHSS

31

45.5% NZ_CP085954.1: Lanthipeptides: LK411_RS13585_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQ

22

+ SKSLCTPGC TG L CF Q

1

ITSKSLCTPGCPTGALG-CFTQ

21

40.6% NZ_CP013655.1: Lanthipeptides: ATZ35_RS03625_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQTITCN

27

+ S SLCT GC Q LQT+ CN

1

ITSVSLCTMGC-----QGSKLQTVICN

22

37.5% NZ_FNDP01000013.1: Lanthipeptides: BLP54_RS11235_lanthipeptide

3

SKSLCTPGCITGPLQTC

19

S SLCTPGC TG L C

3

SISLCTPGCPTGILMGC

19

37.5% NZ_GG667191.1and 1 other:

NZ_GG667191.1 Lanthipeptides: HMPREF0298_RS11685_lanthipeptide

Lanthipeptides: HMPREF0298_RS11685_lanthipeptide

1

VLSKSLCTPGCITGPLQ

17

+ SKSLCTPGCITG +

1

ITSKSLCTPGCITGWMM

17

34.4% NZ_JHXK01000032.1and 1 other:

NZ_JHXK01000032.1 Lanthipeptides: T483_RS30515_lanthipeptide

Lanthipeptides: T483_RS30515_lanthipeptide

1

VLSKSLCTPGCITGPLQTCFLQT

23

V S S CTPGC T +TC ++

1

VTSYSACTPGCATSLFRTCLTRS

23

34.1% NZ_QOCT01000001.1: Lanthipeptides: DS833_RS00365_lanthipeptide

1

VLSKSLCTPGCITGPLQTC

19

+ SKSLCTPGCITG L C

1

ITSKSLCTPGCITGRLMGC

19

31.4% NZ_CP073683.1and 1 other:

NZ_CP092779.1 Lanthipeptides: MJ749_RS08075_lanthipeptide

Lanthipeptides: KAI37_RS08180_lanthipeptide

1

VLSKSLCTPGCITGP

15

V S CTPGCITGP

1

VTSVFACTPGCITGP

15

31.2% NZ_AP025343.1: Lanthipeptides: allorf_1820803_1820973_lanthipeptide

1

VLSKSLCTPGC

11

V SKSLCTPGC

1

VDSKSLCTPGC

11

31.2% NZ_CP015405.2and 1 other:

NZ_CP053228.1 Lanthipeptides: HL650_RS06245_lanthipeptide

Lanthipeptides: A4V09_RS08280_lanthipeptide

1

VLSKSLCTPGCITGPLQTC

19

+ S SLCT GC T TC

1

ITSISLCTSGCKTAFFGTC

19

31.2% NZ_CP023477.1: Lanthipeptides: CO204_RS07210_lanthipeptide

3

SKSLCTPGCI-TGPLQT

18

S SLCTPGC TG +

3

SWSLCTPGCARTGSFNS

19

31.2% NZ_CP047792.1and 1 other:

NZ_JAGSAY010000004.1 Lanthipeptides: KC186_RS06745_lanthipeptide

Lanthipeptides: E3S88_RS07345_lanthipeptide

1

VLSKSLCTPGCI-TGPLQT

18

+ S SLCTPGC TG +

2

ITSHSLCTPGCANTGSFNS

20

31.2% NZ_CP086149.1and 13 others:

NZ_CP086149.1 Lanthipeptides: LL127_RS22600_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22595_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22590_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22585_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22580_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22575_lanthipeptideNZ_CP086149.1 Lanthipeptides: LL127_RS22570_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23225_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23220_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23215_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23210_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23205_lanthipeptideNZ_CP087100.1 Lanthipeptides: LOR37_RS23200_lanthipeptide

Lanthipeptides: LL127_RS22605_lanthipeptide

5

SLCTPGCITGPLQTC

19

SLCT GCITG + C

2

SLCTAGCITGRIMGC

16

28.6% NZ_CP034141.1: Lanthipeptides: EGM68_RS08790_lanthipeptide

3

SKSLCTPGCITGP

15

S S CT GCITGP

3

SWSYCTTGCITGP

15

28.1% NZ_CP013023.1: Lanthipeptides: allorf_0505345_0505512_lanthipeptide

1

VLSKSLCTPGC

11

+ SKSLCTPGC

1

IKSKSLCTPGC

11

28.1% NZ_FMZZ01000002.1: Lanthipeptides: BLS56_RS30480_lanthipeptide

1

VLSKSLCTPGCIT

13

V S SLCTPGC +

1

VTSVSLCTPGCTS

13

28.1% NZ_KI866523.1: Lanthipeptides: MPTA5024_RS39835_lanthipeptide

1

VLSKSLCTPGCIT

13

V S SLCTPGC +

1

VTSWSLCTPGCTS

13

28.1% NZ_QGTF01000010.1: Lanthipeptides: BDW27_RS18560_lanthipeptide

1

VLSKSLCTPGCITGPLQT

18

V S S+CTPGC G +

1

VTSVSVCTPGCENGTFNS

18

28.1% NZ_QSHK01000002.1: Lanthipeptides: DW860_RS04745_lanthipeptide

1

VLSKSLCTPGCITGPLQ

17

+ SKSLCT C TG +

1

ITSKSLCTSSCETGFFK

17

26.5% NZ_CABIWO010000014.1: Lanthipeptides: FY209_RS17155_lanthipeptide

3

SKSLCTPGCITGPL

16

S + CTPGC+TG L

2

SVAYCTPGCVTGQL

15

25.7% NZ_CP075910.1and 3 others:

NZ_CP075971.1 Lanthipeptides: KLF29_RS14850_lanthipeptideNZ_CP075982.1 Lanthipeptides: KLF51_RS14900_lanthipeptideNZ_CP075994.1 Lanthipeptides: KLF26_RS16110_lanthipeptide

Lanthipeptides: KLF45_RS14835_lanthipeptide

1

VLSKSLCTPGCITGPL

16

+ S + CTPGC+TG L

1

ITSVAYCTPGCLTGEL

16

25.7% NZ_JACYTN010000030.1: Lanthipeptides: allorf_08178_08354_lanthipeptide

3

SKSLCTPGCITGPLQTCFLQTI

24

S+ +CTPG +G +C+L T

4

SRIICTPGSCSG--DSCWLTTF

23

25.0% NC_003923.1and 9 others:

NC_009641.1 Lanthipeptides: NWMN_RS09635_lanthipeptideNZ_CP023076.1 Lanthipeptides: CJ017_RS08945_lanthipeptideNZ_CP054876.1 Lanthipeptides: HUW54_RS09150_lanthipeptideNZ_CP077098.1 Lanthipeptides: KSF82_RS09475_lanthipeptideNZ_CP092781.1 Lanthipeptides: ML436_RS08940_lanthipeptideNZ_CP102959.1 Lanthipeptides: NW979_RS08780_lanthipeptideNZ_CP102962.1 Lanthipeptides: NW971_RS09555_lanthipeptideNZ_LR133917.1 Lanthipeptides: ELZ45_RS09155_lanthipeptideNZ_LS483317.1 Lanthipeptides: DQL75_RS09700_lanthipeptide

Lanthipeptides: MW_RS09420_lanthipeptide

1

VLSKSLCTPGC

11

+ S SLCTPGC

2

ITSHSLCTPGC

12

25.0% NC_014023.1and 43 others:

NC_014023.1 Lanthipeptides: BMQ_RS27575_lanthipeptideNZ_CP018875.1 Lanthipeptides: BUW91_RS26425_lanthipeptideNZ_CP018875.1 Lanthipeptides: BUW91_RS26420_lanthipeptideNZ_CP028091.1 Lanthipeptides: C1N54_RS28075_lanthipeptideNZ_CP028091.1 Lanthipeptides: C1N54_RS28070_lanthipeptideNZ_CP028091.1 Lanthipeptides: C1N54_RS28065_lanthipeptideNZ_CP031776.1 Lanthipeptides: D0441_RS30140_lanthipeptideNZ_CP041065.1 Lanthipeptides: FJM50_RS01185_lanthipeptideNZ_CP041065.1 Lanthipeptides: FJM50_RS01180_lanthipeptideNZ_CP041065.1 Lanthipeptides: FJM50_RS01175_lanthipeptideNZ_CP048884.1 Lanthipeptides: BMG_RS27510_lanthipeptideNZ_CP058263.1 Lanthipeptides: HW576_RS26980_lanthipeptideNZ_CP058263.1 Lanthipeptides: HW576_RS26975_lanthipeptideNZ_CP058263.1 Lanthipeptides: HW576_RS26970_lanthipeptideNZ_CP085427.1 Lanthipeptides: LIT30_RS26985_lanthipeptideNZ_CP085427.1 Lanthipeptides: LIT30_RS26980_lanthipeptideNZ_CP085427.1 Lanthipeptides: LIT30_RS26975_lanthipeptideNZ_CP085432.1 Lanthipeptides: LIT34_RS27820_lanthipeptideNZ_CP085432.1 Lanthipeptides: LIT34_RS27815_lanthipeptideNZ_CP085432.1 Lanthipeptides: LIT34_RS27810_lanthipeptideNZ_FNNQ01000006.1 Lanthipeptides: BLV90_RS07690_lanthipeptideNZ_FNNQ01000006.1 Lanthipeptides: BLV90_RS07685_lanthipeptideNZ_FNNQ01000006.1 Lanthipeptides: BLV90_RS07680_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS16000_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS15995_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS15990_lanthipeptideNZ_FPAA01000016.1 Lanthipeptides: CHX35_RS15985_lanthipeptideNZ_JACJHT010000009.1 Lanthipeptides: HNP21_RS25635_lanthipeptideNZ_JACJHT010000009.1 Lanthipeptides: HNP21_RS25630_lanthipeptideNZ_JACJHT010000009.1 Lanthipeptides: HNP21_RS25625_lanthipeptideNZ_JAHHYI010000015.1 Lanthipeptides: KM925_RS26245_lanthipeptideNZ_JANIOE010000010.1 Lanthipeptides: NQ109_RS28075_lanthipeptideNZ_JANIOE010000010.1 Lanthipeptides: NQ109_RS28070_lanthipeptideNZ_JANIOE010000010.1 Lanthipeptides: NQ109_RS28065_lanthipeptideNZ_NKAQ01000005.1 Lanthipeptides: CE057_RS19640_lanthipeptideNZ_NKAQ01000005.1 Lanthipeptides: CE057_RS19635_lanthipeptideNZ_NTZG01000054.1 Lanthipeptides: CN510_RS18265_lanthipeptideNZ_NUIN01000020.1 Lanthipeptides: CN973_RS26930_lanthipeptideNZ_NUOI01000090.1 Lanthipeptides: COE08_RS30285_lanthipeptideNZ_NUOI01000090.1 Lanthipeptides: COE08_RS30280_lanthipeptideNZ_NUOQ01000009.1 Lanthipeptides: COE31_RS05925_lanthipeptideNZ_NUXL01000007.1 Lanthipeptides: COJ36_RS20885_lanthipeptideNZ_NUZS01000089.1 Lanthipeptides: COJ90_RS28785_lanthipeptide

Lanthipeptides: BMQ_RS27580_lanthipeptide

1

VLSKSLCTPGC

11

+ S SLCTPGC

1

ITSVSLCTPGC

11

25.0% NZ_AP019791.1: Lanthipeptides: RxyAA322_RS06460_lanthipeptide

1

VLSKSLCTPGC

11

+ S SLCTPGC

1

ITSYSLCTPGC

11

25.0% NZ_AP023356.1: Lanthipeptides: Aiant_RS23765_lanthipeptide

1

VLSKSLCTPGCIT

13

+ S SLCTPGC +

1

ITSVSLCTPGCTS

13

25.0% NZ_AXWW01000016.1and 1 other:

NZ_JAMTCO010000009.1 Lanthipeptides: LV75_RS20160_lanthipeptide

Lanthipeptides: H504_RS39505_lanthipeptide

1

VLSKSLCTPGCIT

13

+ S SLCTPGC +

1

ITSISLCTPGCTS

13

25.0% NZ_CP007699.2and 1 other:

NZ_KB905819.1 Lanthipeptides: F603_RS34750_lanthipeptide

Lanthipeptides: T261_RS08380_lanthipeptide

1

VLSKSLCTPGCIT

13

V S S CTPGC +

1

VTSISYCTPGCTS

13

25.0% NZ_CP071248.1: Lanthipeptides: BLI009_RS04985_lanthipeptide

3

SKSLCTPGCIT

13

S SLCTPGC +

5

SISLCTPGCTS

15

25.0% NZ_CP094805.1: Lanthipeptides: MUA37_RS13310_lanthipeptide

1

VLSKSLCTPGC

11

+ SK LCTPGC

1

IASKFLCTPGC

11

25.0% NZ_JADDUE010000020.1and 1 other:

NZ_JAMTCQ010000009.1 Lanthipeptides: LY41_RS11610_lanthipeptide

Lanthipeptides: INP57_RS28495_lanthipeptide

1

VLSKSLCTPGCIT

13

V S S CTPGC +

1

VTSVSYCTPGCTS

13

25.0% NZ_VKCY01000012.1: Lanthipeptides: FNK43_RS09020_lanthipeptide

1

VLSKSLCTPGC

11

+ S SLCTPGC

3

ITSFSLCTPGC

13

25.0% NZ_WTWY01000020.1: Lanthipeptides: GQY55_RS27090_lanthipeptide

3

SKSLCTPGCITGPLQ

17

S +CTP C+TG L

1

SGFICTPSCLTGTLN

15

22.9% NZ_CP029639.1and 1 other:

NZ_QLLI01000019.1 Lanthipeptides: DET54_RS28075_lanthipeptide

Lanthipeptides: DMB88_RS07755_lanthipeptide

1

VLSKSLCTPGCITG

14

+ S + CTPGC TG

1

ITSVAYCTPGCNTG

14

22.9% NZ_CP070896.1and 2 others:

NZ_CP070896.1 Lanthipeptides: JWH23_RS09310_lanthipeptideNZ_CP070896.1 Lanthipeptides: JWH23_RS09310_lanthipeptide

Lanthipeptides: JWH23_RS09310_lanthipeptide

1

VLSKSLCTPGCITG

14

+ S + CTPGC+TG

1

IASVAYCTPGCLTG

14

22.7% NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13065_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13065_lanthipeptide

Lanthipeptides: BUE45_RS13065_lanthipeptide

1

VLSKSLCTPG----CITGPLQTCFLQTITCNCH

29

V S ++ PG +T P Q C + C+ H

5

VASPAVAGPGEGAVPVTDPAQPCDDKEKACSGH

37

21.9% NC_006582.1and 6 others:

NZ_BOQQ01000001.1 Lanthipeptides: KI354_RS00530_lanthipeptideNZ_BOQS01000001.1 Lanthipeptides: KI364_RS00675_lanthipeptideNZ_CP019985.1 Lanthipeptides: BC8716_RS09795_lanthipeptideNZ_CP104963.1 Lanthipeptides: N7M99_RS07725_lanthipeptideNZ_FRBS01000002.1 Lanthipeptides: BUC05_RS08990_lanthipeptideNZ_JAODPB010000001.1 Lanthipeptides: N6H06_RS03040_lanthipeptide

Lanthipeptides: ABC_RS22115_lanthipeptide

3

SKSLCTPGC

11

S S CTPGC

3

SVSFCTPGC

11

21.9% NC_007296.2and 72 others:

NC_008021.1 Lanthipeptides: MGAS9429_RS04535_lanthipeptideNC_008022.1 Lanthipeptides: MGAS10270_RS04550_lanthipeptideNC_008024.1 Lanthipeptides: MGAS10750_RS04710_lanthipeptideNZ_AP023389.1 Lanthipeptides: H7675_RS05195_lanthipeptideNZ_CAAHHH010000001.1 Lanthipeptides: E9418_RS00985_lanthipeptideNZ_CAAHHN010000001.1 Lanthipeptides: E9502_RS00800_lanthipeptideNZ_CAAHHN010000001.1 Lanthipeptides: E9502_RS00800_lanthipeptideNZ_CAAHHX010000004.1 Lanthipeptides: E9506_RS04695_lanthipeptideNZ_CAAHKF010000003.1 Lanthipeptides: E9638_RS04280_lanthipeptideNZ_CAAHKK010000012.1 Lanthipeptides: E9649_RS06980_lanthipeptideNZ_CAAHKP010000001.1 Lanthipeptides: E9652_RS01900_lanthipeptideNZ_CAAHKP010000001.1 Lanthipeptides: E9652_RS01900_lanthipeptideNZ_CAAHKQ010000012.1 Lanthipeptides: E9664_RS06700_lanthipeptideNZ_CAAHKY010000001.1 Lanthipeptides: E9668_RS01390_lanthipeptideNZ_CAAHLP010000001.1 Lanthipeptides: E9684_RS01620_lanthipeptideNZ_CAAHLP010000001.1 Lanthipeptides: E9684_RS01620_lanthipeptideNZ_CAAHPW010000003.1 Lanthipeptides: E9938_RS03915_lanthipeptideNZ_CAAHRY010000001.1 Lanthipeptides: E9986_RS01435_lanthipeptideNZ_CAAISW010000004.1 Lanthipeptides: FAK84_RS04845_lanthipeptideNZ_CAAJDG010000002.1 Lanthipeptides: FAO89_RS02535_lanthipeptideNZ_CAAJFC010000001.1 Lanthipeptides: FAP55_RS00880_lanthipeptideNZ_CP007241.1 Lanthipeptides: STAB904_RS04335_lanthipeptideNZ_CP007560.1 Lanthipeptides: DI45_RS04910_lanthipeptideNZ_CP007561.1 Lanthipeptides: DK92_RS04585_lanthipeptideNZ_CP010449.1 Lanthipeptides: SD89_RS04040_lanthipeptideNZ_CP014542.1 Lanthipeptides: AYM92_RS04660_lanthipeptideNZ_CP021920.1 Lanthipeptides: S101395_RS23945_lanthipeptideNZ_CP021920.1 Lanthipeptides: S101395_RS23940_lanthipeptideNZ_CP026082.1 Lanthipeptides: C2E46_RS06835_lanthipeptideNZ_CP032699.1 Lanthipeptides: D8S76_RS04455_lanthipeptideNZ_CP033336.1 Lanthipeptides: EB817_RS05220_lanthipeptideNZ_CP035431.1 Lanthipeptides: ETT68_RS04385_lanthipeptideNZ_CP035440.1 Lanthipeptides: ETT59_RS04870_lanthipeptideNZ_CP035442.1 Lanthipeptides: ETT57_RS04405_lanthipeptideNZ_CP035443.1 Lanthipeptides: ETT56_RS04980_lanthipeptideNZ_CP035446.1 Lanthipeptides: ETT53_RS04795_lanthipeptideNZ_CP035448.1 Lanthipeptides: ETT51_RS04860_lanthipeptideNZ_CP060643.1 Lanthipeptides: H7792_RS04555_lanthipeptideNZ_CP060645.1 Lanthipeptides: H7790_RS04380_lanthipeptideNZ_CP060645.1 Lanthipeptides: H7790_RS04380_lanthipeptideNZ_CP068988.1 Lanthipeptides: DI291_RS01315_lanthipeptideNZ_CP068988.1 Lanthipeptides: DI291_RS01310_lanthipeptideNZ_CP083398.1 Lanthipeptides: K8336_RS19685_lanthipeptideNZ_CP083398.1 Lanthipeptides: K8336_RS19680_lanthipeptideNZ_CP104093.1 Lanthipeptides: N2384_RS28125_lanthipeptideNZ_CP104093.1 Lanthipeptides: N2384_RS28120_lanthipeptideNZ_GL878559.1 Lanthipeptides: HMPREF9391_RS11990_lanthipeptideNZ_HG316453.1 Lanthipeptides: SPYH293_RS03955_lanthipeptideNZ_JADNAZ010000009.1 Lanthipeptides: I2A67_RS14375_lanthipeptideNZ_JADNAZ010000009.1 Lanthipeptides: I2A67_RS14370_lanthipeptideNZ_JADPEB010000003.1 Lanthipeptides: I4U26_RS02400_lanthipeptideNZ_JAGTPZ010000025.1 Lanthipeptides: KEG25_RS05520_lanthipeptideNZ_JAGTPZ010000025.1 Lanthipeptides: KEG25_RS05515_lanthipeptideNZ_JAJBZU010000010.1 Lanthipeptides: LIN83_RS18445_lanthipeptideNZ_JAJBZU010000010.1 Lanthipeptides: LIN83_RS18440_lanthipeptideNZ_JALDUY010000002.1 Lanthipeptides: M1G21_RS04840_lanthipeptideNZ_JAQCST010000015.1 Lanthipeptides: PGZ09_RS08160_lanthipeptideNZ_KV810616.1 Lanthipeptides: HMPREF2877_RS10480_lanthipeptideNZ_KV832031.1 Lanthipeptides: HMPREF2637_RS10850_lanthipeptideNZ_LRGI01000007.1 Lanthipeptides: AWT85_RS02610_lanthipeptideNZ_LS483337.1 Lanthipeptides: DQL03_RS04375_lanthipeptideNZ_LS483347.1 Lanthipeptides: DQM50_RS05905_lanthipeptideNZ_LS483347.1 Lanthipeptides: DQM50_RS05905_lanthipeptideNZ_LS483382.1 Lanthipeptides: DQM89_RS04695_lanthipeptideNZ_LS483382.1 Lanthipeptides: DQM89_RS04695_lanthipeptideNZ_LS483389.1 Lanthipeptides: DQM81_RS05230_lanthipeptideNZ_LS483430.1 Lanthipeptides: DQN28_RS04075_lanthipeptideNZ_LT906439.1 Lanthipeptides: CKV83_RS02205_lanthipeptideNZ_NIKH01000009.1 Lanthipeptides: CHCC20372_RS05150_lanthipeptideNZ_NIKH01000009.1 Lanthipeptides: CHCC20372_RS05145_lanthipeptideNZ_RZIR01000001.1 Lanthipeptides: allorf_3294587_3294754_lanthipeptideNZ_RZIR01000001.1 Lanthipeptides: ELY93_RS16790_lanthipeptide

Lanthipeptides: M28_RS04095_lanthipeptide

1

VLSKSLCTPG

10

V S+ LCTPG

1

VGSRYLCTPG

10

21.9% NC_014483.2and 30 others:

NC_014622.2 Lanthipeptides: PPSC2_RS36205_lanthipeptideNC_017542.1 Lanthipeptides: PPM_RS07465_lanthipeptideNC_023037.2 Lanthipeptides: X809_RS07820_lanthipeptideNZ_CP006872.1 Lanthipeptides: PPSQR21_RS07740_lanthipeptideNZ_CP017967.2 Lanthipeptides: PPYC1_RS07755_lanthipeptideNZ_CP017968.3 Lanthipeptides: PPYC2_RS08330_lanthipeptideNZ_CP023711.1 Lanthipeptides: CPY53_RS22235_lanthipeptideNZ_CP025957.1 Lanthipeptides: C1A50_RS07530_lanthipeptideNZ_CP029370.1 Lanthipeptides: DI243_RS07495_lanthipeptideNZ_CP040829.1 Lanthipeptides: FGY93_RS00500_lanthipeptideNZ_CP049598.1 Lanthipeptides: G7L40_RS00115_lanthipeptideNZ_CP061172.1 Lanthipeptides: IAQ67_RS07480_lanthipeptideNZ_CP073682.1 Lanthipeptides: KAI36_RS07745_lanthipeptideNZ_CP073683.1 Lanthipeptides: KAI37_RS07495_lanthipeptideNZ_CP084033.1 Lanthipeptides: LAZ93_RS07550_lanthipeptideNZ_CP085682.1 Lanthipeptides: LJR53_RS07370_lanthipeptideNZ_CP086373.1 Lanthipeptides: LMH85_RS07780_lanthipeptideNZ_CP092779.1 Lanthipeptides: MJ749_RS07440_lanthipeptideNZ_CP097766.1 Lanthipeptides: MF620_RS07485_lanthipeptideNZ_CP102865.1 Lanthipeptides: NWS42_RS21195_lanthipeptideNZ_CP109848.1 Lanthipeptides: OF859_RS22650_lanthipeptideNZ_CP113973.1 Lanthipeptides: OYT09_RS07785_lanthipeptideNZ_FOYG01000001.1 Lanthipeptides: BM358_RS03525_lanthipeptideNZ_JAAMNR010000001.1 Lanthipeptides: G9G54_RS03500_lanthipeptideNZ_JAKVDC010000001.1 Lanthipeptides: MKN04_RS02755_lanthipeptideNZ_JWJJ01000002.1 Lanthipeptides: U707_RS10390_lanthipeptideNZ_PNXQ01000013.1 Lanthipeptides: C1I60_RS14430_lanthipeptideNZ_POVS01000009.1 Lanthipeptides: C1T21_RS10630_lanthipeptideNZ_POVT01000009.1 Lanthipeptides: C1T20_RS05900_lanthipeptideNZ_PTJM01000020.1 Lanthipeptides: C5G87_RS02825_lanthipeptide

Lanthipeptides: PPE_RS07020_lanthipeptide

6

LCTPGCITGPLQ

17

+CTP C TG L

4

ICTPSCATGTLN

15

21.9% NC_022873.1and 93 others:

NZ_CM000742.1 Lanthipeptides: BMYCO0001_RS26515_lanthipeptideNZ_CP011151.1 Lanthipeptides: WR47_RS18180_lanthipeptideNZ_CP011151.1 Lanthipeptides: WR47_RS18175_lanthipeptideNZ_CP011151.1 Lanthipeptides: WR47_RS18170_lanthipeptideNZ_CP011151.1 Lanthipeptides: WR47_RS18165_lanthipeptideNZ_CP015350.1 Lanthipeptides: BT246_RS19775_lanthipeptideNZ_CP015350.1 Lanthipeptides: BT246_RS19770_lanthipeptideNZ_CP015350.1 Lanthipeptides: BT246_RS19765_lanthipeptideNZ_CP017060.1 Lanthipeptides: FORC47_RS18710_lanthipeptideNZ_CP017060.1 Lanthipeptides: FORC47_RS18705_lanthipeptideNZ_CP017060.1 Lanthipeptides: FORC47_RS18700_lanthipeptideNZ_CP026678.1 Lanthipeptides: C2I25_RS21370_lanthipeptideNZ_CP026678.1 Lanthipeptides: C2I25_RS21365_lanthipeptideNZ_CP026678.1 Lanthipeptides: C2I25_RS21360_lanthipeptideNZ_CP035965.1 Lanthipeptides: EXW35_RS16385_lanthipeptideNZ_CP035965.1 Lanthipeptides: EXW35_RS16380_lanthipeptideNZ_CP035994.1 Lanthipeptides: EXW32_RS16155_lanthipeptideNZ_CP035994.1 Lanthipeptides: EXW32_RS16150_lanthipeptideNZ_CP035994.1 Lanthipeptides: EXW32_RS16145_lanthipeptideNZ_CP035994.1 Lanthipeptides: EXW32_RS16140_lanthipeptideNZ_CP035999.1 Lanthipeptides: EXW27_RS26195_lanthipeptideNZ_CP035999.1 Lanthipeptides: EXW27_RS26190_lanthipeptideNZ_CP035999.1 Lanthipeptides: EXW27_RS26185_lanthipeptideNZ_CP035999.1 Lanthipeptides: EXW27_RS26180_lanthipeptideNZ_CP036099.1 Lanthipeptides: EXW47_RS16265_lanthipeptideNZ_CP036099.1 Lanthipeptides: EXW47_RS16260_lanthipeptideNZ_CP036099.1 Lanthipeptides: EXW47_RS16255_lanthipeptideNZ_CP036099.1 Lanthipeptides: EXW47_RS16250_lanthipeptideNZ_CP036117.1 Lanthipeptides: EXW43_RS16620_lanthipeptideNZ_CP036117.1 Lanthipeptides: EXW43_RS16615_lanthipeptideNZ_CP036117.1 Lanthipeptides: EXW43_RS16610_lanthipeptideNZ_CP036117.1 Lanthipeptides: EXW43_RS16605_lanthipeptideNZ_CP036145.1 Lanthipeptides: EXW57_RS16110_lanthipeptideNZ_CP036145.1 Lanthipeptides: EXW57_RS16105_lanthipeptideNZ_CP036145.1 Lanthipeptides: EXW57_RS16100_lanthipeptideNZ_CP036145.1 Lanthipeptides: EXW57_RS16095_lanthipeptideNZ_CP040334.1 Lanthipeptides: EUC39_RS14125_lanthipeptideNZ_CP040334.1 Lanthipeptides: EUC39_RS14120_lanthipeptideNZ_CP040334.1 Lanthipeptides: EUC39_RS14115_lanthipeptideNZ_CP045606.2 Lanthipeptides: GE376_RS18355_lanthipeptideNZ_CP045606.2 Lanthipeptides: GE376_RS18350_lanthipeptideNZ_CP045606.2 Lanthipeptides: GE376_RS18345_lanthipeptideNZ_CP047366.1 Lanthipeptides: GSN03_RS15835_lanthipeptideNZ_CP047366.1 Lanthipeptides: GSN03_RS15830_lanthipeptideNZ_CP071811.1 Lanthipeptides: EXW36_RS16415_lanthipeptideNZ_CP071811.1 Lanthipeptides: EXW36_RS16410_lanthipeptideNZ_CP071811.1 Lanthipeptides: EXW36_RS16405_lanthipeptideNZ_CP072061.1 Lanthipeptides: J5V93_RS15130_lanthipeptideNZ_CP072061.1 Lanthipeptides: J5V93_RS15125_lanthipeptideNZ_CP072061.1 Lanthipeptides: J5V93_RS15120_lanthipeptideNZ_CP084035.1 Lanthipeptides: LCF45_RS15990_lanthipeptideNZ_CP084035.1 Lanthipeptides: LCF45_RS15985_lanthipeptideNZ_CP084035.1 Lanthipeptides: LCF45_RS15980_lanthipeptideNZ_CP084035.1 Lanthipeptides: LCF45_RS15975_lanthipeptideNZ_CP093291.1 Lanthipeptides: MN093_RS25975_lanthipeptideNZ_CP093291.1 Lanthipeptides: MN093_RS25970_lanthipeptideNZ_CP093291.1 Lanthipeptides: MN093_RS25965_lanthipeptideNZ_CP093291.1 Lanthipeptides: MN093_RS25960_lanthipeptideNZ_CP093835.1 Lanthipeptides: MN034_RS15810_lanthipeptideNZ_CP093835.1 Lanthipeptides: MN034_RS15805_lanthipeptideNZ_CP093835.1 Lanthipeptides: MN034_RS15800_lanthipeptideNZ_CP093835.1 Lanthipeptides: MN034_RS15795_lanthipeptideNZ_JAIPUK010000008.1 Lanthipeptides: K9P71_RS24265_lanthipeptideNZ_JAIPUK010000008.1 Lanthipeptides: K9P71_RS24260_lanthipeptideNZ_JANCTB010000001.1 Lanthipeptides: NMG90_RS06155_lanthipeptideNZ_JANCTB010000001.1 Lanthipeptides: NMG90_RS06150_lanthipeptideNZ_JANCTB010000001.1 Lanthipeptides: NMG90_RS06145_lanthipeptideNZ_JANCTB010000001.1 Lanthipeptides: NMG90_RS06140_lanthipeptideNZ_JH792114.1 Lanthipeptides: II3_RS21535_lanthipeptideNZ_JH792114.1 Lanthipeptides: II3_RS21530_lanthipeptideNZ_JH792114.1 Lanthipeptides: II3_RS21525_lanthipeptideNZ_JH792251.1 Lanthipeptides: III_RS11095_lanthipeptideNZ_JH792251.1 Lanthipeptides: III_RS11090_lanthipeptideNZ_JH792251.1 Lanthipeptides: III_RS11085_lanthipeptideNZ_JH792251.1 Lanthipeptides: III_RS11080_lanthipeptideNZ_JH792251.1 Lanthipeptides: III_RS11075_lanthipeptideNZ_KB976712.1 Lanthipeptides: IKQ_RS17500_lanthipeptideNZ_LDGT01000041.1 Lanthipeptides: ABE17_RS18900_lanthipeptideNZ_LDGT01000041.1 Lanthipeptides: ABE17_RS18895_lanthipeptideNZ_LDGT01000041.1 Lanthipeptides: ABE17_RS18890_lanthipeptideNZ_LDGT01000041.1 Lanthipeptides: ABE17_RS18885_lanthipeptideNZ_LDHL01000037.1 Lanthipeptides: ABD98_RS26430_lanthipeptideNZ_LDHL01000037.1 Lanthipeptides: ABD98_RS26425_lanthipeptideNZ_MOOL01000076.1 Lanthipeptides: BK733_RS27280_lanthipeptideNZ_MOOL01000076.1 Lanthipeptides: BK733_RS27275_lanthipeptideNZ_MOOL01000076.1 Lanthipeptides: BK733_RS27270_lanthipeptideNZ_MSTN01000016.1 Lanthipeptides: BVF97_RS28620_lanthipeptideNZ_NIUP01000011.1 Lanthipeptides: CEU84_RS08145_lanthipeptideNZ_NIUP01000011.1 Lanthipeptides: CEU84_RS08140_lanthipeptideNZ_NKAX01000026.1 Lanthipeptides: CE086_RS26165_lanthipeptideNZ_NKAX01000026.1 Lanthipeptides: CE086_RS26160_lanthipeptideNZ_NVGU01000011.1 Lanthipeptides: COL71_RS14760_lanthipeptideNZ_NVGU01000011.1 Lanthipeptides: COL71_RS14755_lanthipeptide

Lanthipeptides: YBT1518_RS19670_lanthipeptide

1

VLSKSLCTPGC

11

+ S S CTPGC

1

ITSISACTPGC

11

21.9% NZ_CP029370.1and 2 others:

NZ_JAFJXZ010000017.1 Lanthipeptides: JYU28_RS14110_lanthipeptideNZ_JAOYTP010000003.1 Lanthipeptides: OIU26_RS10605_lanthipeptide

Lanthipeptides: DI243_RS22305_lanthipeptide

10

GCITGPLQTCFLQTITCNC

28

G +T + C+ +TCNC

4

GTVTCAVSACYDTYVTCNC

22

21.9% NZ_CP048882.1and 1 other:

NZ_CP048882.1 Lanthipeptides: G4Z16_RS06545_lanthipeptide

Lanthipeptides: G4Z16_RS06545_lanthipeptide

1

VLSKSLCTPGCIT

13

+ S S CTPGC +

1

ITSISYCTPGCTS

13

21.9% NZ_CP059572.1: Lanthipeptides: AGRA3207_RS17530_lanthipeptide

1

VLSKSLCTPGCIT

13

V S ++CTPGC +

1

VTSHAVCTPGCTS

13

21.9% NZ_CP090942.1: Lanthipeptides: LZT96_RS12010_lanthipeptide

1

VLSKSLCTPGC

11

+ SK +CTPGC

1

IASKFICTPGC

11

21.9% NZ_FMHI01000015.1and 2 others:

NZ_LIVZ01000011.1 Lanthipeptides: AMK31_RS29125_lanthipeptideNZ_LIXJ01000007.1 Lanthipeptides: AMK22_RS13160_lanthipeptide

Lanthipeptides: H180DRAFT_RS21560_lanthipeptide

1

VLSKSLCTPGCIT

13

+ S S CTPGC +

1

ITSVSYCTPGCTS

13

21.9% NZ_JACHEM010000003.1and 3 others:

NZ_JAMHJQ010000009.1 Lanthipeptides: M1203_RS22635_lanthipeptideNZ_KN039946.1 Lanthipeptides: FM21_RS35825_lanthipeptideNZ_LIPF01000002.1 Lanthipeptides: AMK11_RS10850_lanthipeptide

Lanthipeptides: HNQ79_RS07795_lanthipeptide

1

VLSKSLCTPGCIT

13

+ S S CTPGC +

1

ITSVSWCTPGCTS

13

21.9% NZ_JAIFIS010000001.1: Lanthipeptides: K1X09_RS26315_lanthipeptide

6

LCTPGCITGPLQ

17

+CTP C+TG L

4

ICTPSCLTGTLN

15

21.9% NZ_JAQEAZ010000004.1: Lanthipeptides: PGT18_RS05860_lanthipeptide

5

SLCTPGCITG

14

S CTP C TG

5

SFCTPNCPTG

14

21.9% NZ_JHXK01000032.1: Lanthipeptides: T483_RS31040_lanthipeptide

1

VLSKSLCTPGCITGPLQ

17

+ S+ LCT C T +Q

1

ITSRILCTSSCYTQFIQ

17

21.9% NZ_LELK01000004.1: Lanthipeptides: AB986_RS12540_lanthipeptide

1

VLSKSLCTPGC

11

+ S S CTPGC

1

ITSYSFCTPGC

11

21.9% NZ_NIST01000001.1: Lanthipeptides: CD001_RS09870_lanthipeptide

3

SKSLCTPGCITGPLQ

17

+ +CTP C+TG L

1

TGGICTPSCLTGTLN

15

20.6% NC_021022.1and 2 others:

NC_021022.1 Lanthipeptides: CK5_RS17320_lanthipeptideNZ_JADNJR010000016.1 Lanthipeptides: I2E58_RS10870_lanthipeptide

Lanthipeptides: CK5_RS17320_lanthipeptide

5

SLCTPGCITG

14

S CTP C+TG

7

SFCTPNCLTG

16

18.8% NZ_FNNQ01000013.1: Lanthipeptides: BLV90_RS16000_lanthipeptide

6

LCTPGCITGPLQT

18

+CTPGC G ++

2

ICTPGCDEGTFES

14

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

allorf_1904_2083 - Class I

Cleavage pHMM score: 27.80

RODEO score: 26

Monoisotopic mass: 3264.7 Da

Molecular weight: 3266.9 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 3284.9 Da N = 1; 3302.9 Da N = 2; 3321.0 Da N = 3

gnlProkkaOHOOHJJF_10 - Region 1 - NRPS

Download region GenBank file

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Location: 1 - 6,752 nt. (total: 6,752 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 6752:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Phe) + (Asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg10_1

Search NORINE for peptide: strict or relaxed

AMP-binding (264..665): Asp

nrpys: Asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asp (Asp)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGHVGK
Nearest Stachelhaus code(s):: Asp DLTKIGHVGK (65% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg10_2

Search NORINE for peptide: strict or relaxed

AMP-binding (157..548): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Unpolar aromatic ring (Phe, Trp)
Single AA prediction:: phe (Phe)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWTIAAICK
Nearest Stachelhaus code(s):: Phe DAWTIAAICK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_15 - Region 1 - terpene

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Location: 1 - 6,562 nt. (total: 6,562 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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gnlProkkaOHOOHJJF_42 - Region 1 - NRPS

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Location: 1 - 3,708 nt. (total: 3,708 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 3708:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg42_1

Search NORINE for peptide: strict or relaxed

AMP-binding (463..868): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code(s):: Glu DAWHFGGVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_54 - Region 1 - NRPS-like

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Location: 1 - 2,868 nt. (total: 2,868 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 2868:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Val)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg54_1

Search NORINE for peptide: strict or relaxed

AMP-binding (248..645): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWLGGTFK
Nearest Stachelhaus code(s):: Val DAFWLGGTFK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_79 - Region 1 - transAT-PKS-like

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Location: 23,114 - 69,018 nt. (total: 45,905 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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NRPS/PKS products

Predicted core structure(s)

For candidate cluster 1, location 23113 - 69018:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ccmal) + (ohmal - mal) + (Me-ccmal) + (mal)
Non-colinear ordering:: ctg79_59 + ctg79_58 + ctg79_57 + ctg79_56

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

gnlProkkaOHOOHJJF_173 - Region 1 - transAT-PKS

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Location: 1 - 53,656 nt. (total: 53,656 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

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NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 53656:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ccmal - ccmal) + (ccmal) + (ccmal - mal) + (ccmal - mal) + (ohmal) + (ohmal - mal)
Non-colinear ordering:: ctg125_2 + ctg125_3 + ctg125_4 + ctg125_5 + ctg125_6 + ctg125_7 + ctg125_8

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg125_1

PKS_AT (37..315): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 91.9
inactive: 31.2
Methoxymalonyl-CoA: 26.1
Methylmalonyl-CoA: 19.6
Propionyl-CoA: 16.9
fatty_acid: 13.9
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

gnlProkkaOHOOHJJF_182 - Region 1 - PKS-like

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Location: 1 - 25,161 nt. (total: 25,161 nt) Show pHMM detection rules used

Region on contig edge.

PKS-like: (t2pks2 or ksIII)

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gnlProkkaOHOOHJJF_183 - Region 1 - other

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Location: 5,966 - 47,384 nt. (total: 41,419 nt) Show pHMM detection rules used

other: (LmbU or Neocarzinostat or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

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gnlProkkaOHOOHJJF_184 - Region 1 - NRPS,transAT-PKS

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Location: 1 - 46,552 nt. (total: 46,552 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 46552:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal - Asn) + (D-Tyr - D-Asn - Gln - Pro) + (D-Asn - Ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg130_7

Search NORINE for peptide: strict or relaxed

AMP-binding (209..604): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asn (Asn)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code(s):: Asn DLTKIGEVGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1719..2126): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: ser (Ser)
Single AA prediction:: ser (Ser)

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSLIDK
Nearest Stachelhaus code(s):: Ser DVWHFSLIDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg130_8

Search NORINE for peptide: strict or relaxed

AMP-binding (211..605): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DALSVGEVVK
Nearest Stachelhaus code(s):: Tyr DALSVGEVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1722..2117): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asn (Asn)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code(s):: Asn DLTKIGEVGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (3231..3636): Gln

nrpys: Gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDLGVVDK
Nearest Stachelhaus code(s):: Gln DAQDLGVVDK (100% 8Å match); Ile DAQDLGVVDK (74% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (4280..4676): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code(s):: Pro DVQFIAHVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg130_9

Search NORINE for peptide: strict or relaxed

CAL_domain (36..478): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 624.6
NH2: 18.6
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (2956..3351): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asn (Asn)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code(s):: Asn DLTKIGEVGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg130_10

PKS_AT (6..290): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 72.2
inactive: 30.7
Methoxymalonyl-CoA: 19.0
Propionyl-CoA: 9.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Methylmalonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

gnlProkkaOHOOHJJF_203 - Region 1 - NRPS,transAT-PKS

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Location: 1 - 33,505 nt. (total: 33,505 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 33505:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Asn - Gly) + (ccmal) + (ccmal) + (mal - D-Glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg149_1

Search NORINE for peptide: strict or relaxed

AMP-binding (281..675): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asn (Asn)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code(s):: Asn DLTKIGEVGK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1783..2176): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQMGMIWK
Nearest Stachelhaus code(s):: Gly DILQMGMVWK (85% 8Å match)
Stachelhaus code match:: 90% (moderate)

ctg149_2

PKS_AT (6..293): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 75.0%; 2-Methylbutyryl-CoA: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 111.1
inactive: 50.8
Methoxymalonyl-CoA: 39.3
Isobutyryl-CoA: 31.6
Methylmalonyl-CoA: 29.7
Propionyl-CoA: 12.0
CHC-CoA: 10.8
fatty_acid: 10.4
Benzoyl-CoA: 10.0
trans-1,2-CPDA: 0.0
Ethylmalonyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg149_6

Search NORINE for peptide: strict or relaxed

AMP-binding (1200..1601): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDIGVVDK
Nearest Stachelhaus code(s):: Glu DAKDIGVVDK (85% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_206 - Region 1 - NRP-metallophore,NRPS

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Location: 1 - 30,555 nt. (total: 30,555 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 30555:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg152_6

Search NORINE for peptide: strict or relaxed

AMP-binding (480..879): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code(s):: Gly DILQLGLIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1537..1953): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg152_8

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): diOH-Bz

nrpys: diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code(s):: diOH-Bz PLPAQGVVNK (100% 8Å match); diOH-Bz or Sal PLPAQGVVNK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_207 - Region 1 - NRPS,betalactone

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Location: 2,602 - 30,211 nt. (total: 27,610 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

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Predicted core structure(s)

For candidate cluster 1, location 2601 - 30211:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Tyr) + (Ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg153_19

AMP-binding (6..186): X

nrpys: (unknown)

SVM prediction details:

NOTE: uncertain match

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ---HIAAPVK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

ctg153_23

Search NORINE for peptide: strict or relaxed

AMP-binding (473..866): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: ile (Ile)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code(s):: Ile DAFFYGITFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg153_24

Search NORINE for peptide: strict or relaxed

AMP-binding (202..594): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code(s):: Tyr DGTITAEVAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_210 - Region 1 - transAT-PKS-like

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Location: 1 - 23,214 nt. (total: 23,214 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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NRPS/PKS products

Predicted core structure(s)

For candidate cluster 1, location 0 - 23214:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ccmal) + (ohmal - mal) + (mal)
Non-colinear ordering:: ctg156_1 + ctg156_3 + ctg156_2

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

gnlProkkaOHOOHJJF_214 - Region 1 - NRPS

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Location: 1 - 21,521 nt. (total: 21,521 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 21521:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Cys - Ser - Cys - Ala) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg160_1

AMP-binding (299..684): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DQGSEGTVNK
Nearest Stachelhaus code(s):: 4-ohGln or Gln DQGITGTVTK (50% 8Å match)
Stachelhaus code match:: 70% (weak)

ctg160_2

Search NORINE for peptide: strict or relaxed

CAL_domain (44..474): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 114.8
Acetyl-CoA: 26.6
NH2: 24.7
shikimic_acid: 0.0
AHBA: 0.0

AMP-binding (1130..1514): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSLIWK
Nearest Stachelhaus code(s):: Cys DLYNMSLIWK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2620..3019): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: ser (Ser)
Single AA prediction:: ser (Ser)

Stachelhaus prediction details:

Stachelhaus sequence:: DVWQIILVNK
Nearest Stachelhaus code(s):: Ser DVWHISLVDK (59% 8Å match)
Stachelhaus code match:: 70% (weak)

AMP-binding (3938..4322): Cys

nrpys: Cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Small clusters prediction:: Polar, uncharged (aliphatic with -SH) (Cys)
Single AA prediction:: Polar, uncharged (aliphatic with -SH) (Cys)

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNMSLIWK
Nearest Stachelhaus code(s):: Cys DLYNMSLIWK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (4965..5358): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: DVWCIAMVYK
Nearest Stachelhaus code(s):: Ser DVWSIAMVHK (82% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaOHOOHJJF_227 - Region 1 - NRPS,T3PKS,transAT-PKS

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Location: 1 - 91,820 nt. (total: 91,820 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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Predicted core structure(s)

For candidate cluster 1, location 0 - 91820:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal) + (Me-ccmal - ohmal) + (Ala - ccmal - ccmal - Me-ccmal) + (mal - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg173_2

PKS_AT (8..289): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 100.0
inactive: 46.8
Methoxymalonyl-CoA: 38.9
Methylmalonyl-CoA: 25.3
Propionyl-CoA: 23.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg173_3

PKS_AT (7..293): mal

ATSignature: (unknown)

No matches above 50%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 35.4
inactive: 26.4
Methoxymalonyl-CoA: 14.9
Benzoyl-CoA: 14.0
Methylmalonyl-CoA: 9.2
Isobutyryl-CoA: 8.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg173_4

PKS_AT (4..282): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 92.8
inactive: 28.2
Methoxymalonyl-CoA: 23.4
Methylmalonyl-CoA: 11.0
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg173_9

Search NORINE for peptide: strict or relaxed

CAL_domain (74..476): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 26.7
NH2: 9.4
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1145..1540): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code(s):: Gly DILQLGMIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg173_12

Search NORINE for peptide: strict or relaxed

AMP-binding (492..896): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSNMAIIYK
Nearest Stachelhaus code(s):: Ala DVSNMAIIYK (88% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_231 - Region 1 - NRPS

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Location: 1 - 15,139 nt. (total: 15,139 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 15139:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Orn) + (Tyr - D-Thr) + (Glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg177_1

Search NORINE for peptide: strict or relaxed

AMP-binding (468..873): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGGVDK
Nearest Stachelhaus code(s):: Glu DAWHFGGVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg177_2

Search NORINE for peptide: strict or relaxed

AMP-binding (474..867): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTLTAEVAK
Nearest Stachelhaus code(s):: Tyr DGTLTAEVAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1509..1905): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg177_3

Search NORINE for peptide: strict or relaxed

AMP-binding (203..608): Orn

nrpys: Orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: Orn and hydroxy-Orn specific (Orn, OH-Orn)
Single AA prediction:: orn (Orn)

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEVGSIDK
Nearest Stachelhaus code(s):: Orn DVGEVGSIDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaOHOOHJJF_232 - Region 1 - T3PKS

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Location: 1 - 14,956 nt. (total: 14,956 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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gnlProkkaOHOOHJJF_234 - Region 1 - transAT-PKS

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Location: 1 - 14,753 nt. (total: 14,753 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 14753:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg180_3

AMP-binding (15..363): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: IGNPTGTIFK
Nearest Stachelhaus code(s):: 2,3-dohHda IGNPTGTIMK (74% 8Å match)
Stachelhaus code match:: 90% (moderate)

ctg180_6

PKS_AT (4..281): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 87.7
inactive: 30.9
Methoxymalonyl-CoA: 29.3
Methylmalonyl-CoA: 21.7
Propionyl-CoA: 16.5
2-Methylbutyryl-CoA: 15.4
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

gnlProkkaOHOOHJJF_238 - Region 1 - terpene

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Location: 60,713 - 81,453 nt. (total: 20,741 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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gnlProkkaOHOOHJJF_253 - Region 1 - NRPS

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Location: 1 - 9,379 nt. (total: 9,379 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 9379:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X) + (Pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg199_1

Search NORINE for peptide: strict or relaxed

AMP-binding (469..866): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code(s):: Pro DVQFIAHVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1500..1879): Gln

nrpys: Gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGSVEK
Nearest Stachelhaus code(s):: Gln DAWHFGSVEK (100% 8Å match); Glu DAWHFGSVEK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg199_2

AMP-binding (193..586): X

nrpys: Ala, Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code(s):: Ala or Val DVFWIGGTFK (97% 8Å match); Val DVFWIGGTFK (94% 8Å match)
Stachelhaus code match:: 100% (strong)