LOCUS       gnlProkkaEPOOICEK_65    6708 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EPOOICEK_65.
ACCESSION   gnlProkkaEPOOICEK_65
VERSION     gnlProkkaEPOOICEK_65
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 12:18:07
            Original ID  :: gnl|Prokka|EPOOICEK_65
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6708
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6708
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3513:6405]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3514..6405
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6708
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6708
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(637..1845)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 278.7; E-value: 1.3e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MNKKEQQNTYLLVGSRIISRVGDIMFDFANNTFLSSVNVKSLMLV
                     GIYQTLENIISVIFNLFGGVLSDNFQRKRIIILTDILSGVLCLALSFISNQQWLIYAVV
                     ITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITVVKVVVPLVSVSLYGLL
                     GLYGILRLDGITFIASGLLILFIRPILEESTGKQVFSLSKIFSDLFEGGRYLASQKEIL
                     YLVILSAIVNFFLAAYNLLLPYSNQMFPRVTVGLYGVFLGAEAVGGLIGASLSSILNKV
                     LKIKTMILYLGVSGVFLSLTPMVYCVFPSAYMLALYPALFNLFLTMFNLQFFSYIQKNV
                     DNVFLGRVFGIIFTVAILFMPIGTMTFTFLLSPKNIFNFVIVGLSIGGISLLFYRIFSK
                     RLR"
     CDS             complement(1871..3517)
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MSIYKDIVEGYQLNNIQEKDKLNNVLVQLNEKDDQEMINRKNFIG
                     HFTASAFVISKDNRRLLMVHHNILKRYLQPGGHIDKNDRNPLDAAKRELFEETGIDSEI
                     LTYQCAEPLNSLIPFNVSVHKIPENKLKNERSHYHYDLQYLFYIENEVDVKIDSNESSS
                     YEWIQLDNVKDMDGYKEIIKKIEKLEAASQERFLSNMLKGASFEDISCITVQHIIPSTI
                     PIIMTLQKIFGHRLLVCAKPNSVDKMVWHKLENMGVRLTLASRDEYFNVDYLGIKSKTI
                     LLDIGGYFASIAQIPNLPIECIIEDTENGIQKYENVIDQIEYPLFSVARNPLKKNEDYL
                     VGADIVFGTDYILHQKNLLMQYMQVVCIGYGKIGYGICTKLRELGIRPKVLEKDSMRTI
                     QAVRDGCDILLEKDFKNIDLIFCATGSKSLDILDFRSIKDGTFLVSATSSDDEFNYSYL
                     LDEYEEIVETSLITRYESEDNYFYLLNQGTPTNFVVNSALGNYILLVQAAILYTAKKFI
                     EDREMAIAKQVNTLSDEDNYNIAKQWLEEFC"
     CDS             complement(3514..6405)
                     /NRPS_PKS="Domain: AMP-binding (6-388). E-value: 5.4e-65.
                     Score: 211.4. Matches aSDomain:
                     nrpspksdomains_ctg48_3_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     173.2; E-value: 1.2e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_3"
                     /sec_met_domain="AMP-binding (E-value: 3.8e-64, bitscore:
                     204.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-07, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILKTFSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLL
                     NSDEETVPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDR
                     DVKLENHSVTLLVLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNID
                     WLVKEFYKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGET
                     IEQKKITHLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRV
                     FNLYGPSETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVT
                     EGYRLQPELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQVNGIRIELDEVK
                     SIVDKLKTVKSSRVVFYKKKLVVFYEADLNIKEDIIRSLPSYLNPTVVKVESYYLNQNR
                     KLDVPKMLEIYYYKKQSQQGDDVRKNILDVLSKFERVDITDLDSLELVRFYLEIEDIFD
                     IEIKENDFYRLKSVDSIVDYIRNKSFFQERSTEPNDSFTKEHDLVNLEYNLTKMNYRYL
                     KNIITPSPTQKRLYKNNQNRVIGFNLALEEVTYLELNKLHHIIKYLSYKIDIFRLVVEK
                     EQTRFSIGIVNEGDYSPNIIVLNNLPTELELQGILDNIEVIPIPIIVVGTRDKKVRFYF
                     PYHSIDASSLNKLGDTVYQLYEKKIVIDEVPSSSLVAFSQFKREVLQNDVSGDVLARLP
                     KIKPAIEFEKLNDEVQCFQVSLPEDIKGDDVYLFTIYAISQCILSDYNLSAISGGLSLD
                     FRDYEQFDAYDLIGDIHKKIPFQVNRTETFEEFKNSHFKILEIYRTGIDYYEIAMLGND
                     MSAKEVQERLNNLSLSINFIGEAFRLKDTINNIIDVDFDKNFINVFVHERFAYAVIKSE
                     LLSNSVYDLMHKDSKFELKVIDKKRLENEETNR"
     CDS_motif       complement(4585..4632)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_3_0004"
                     /evalue="1.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg48_3"
                     /protein_end="607"
                     /protein_start="591"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="NNQNRVIGFNLALEEV"
     CDS_motif       complement(5212..5268)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_3_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg48_3"
                     /protein_end="398"
                     /protein_start="379"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SRIDSQVQVNGIRIELDEV"
     aSDomain        complement(5242..6387)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg48_3_AMP-binding.1"
                     /evalue="5.40E-65"
                     /label="ctg48_3_AMP-binding.1"
                     /locus_tag="ctg48_3"
                     /protein_end="388"
                     /protein_start="6"
                     /score="211.4"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLLNSDEET
                     VPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDRDVKLEN
                     HSVTLLVLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNIDWLVKEF
                     YKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGETIEQKKI
                     THLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRVFNLYGP
                     SETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVTEGYRLQ
                     PELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQV"
     CDS_motif       complement(5344..5415)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_3_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg48_3"
                     /protein_end="354"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ELLIGGNGVTEGYRLQPELNKAKF"
     CDS_motif       complement(5932..5988)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg48_3_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg48_3"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AHIICTSGTTGVPKKVFLT"
     CDS             complement(6594..6707)
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MLEELQKDGTLAKLAEKFFGNKDYIPTKDALKVPSKK"
ORIGIN
        1 aatcaaagtg ataagaaaat actatcacct aaaaatatca attgtttgac aaagagccga
       61 attgcttcgt ctttctgaac gcagacgggt tgtcttaaac gacatggtag ctctagctca
      121 gcctttacca gagtatgaca tcttacggtc aattcctggc atcgcagaaa ccacagcgac
      181 atctatcatt ggcgaattgg gagatattcg tcgcagtata ccaatcaaat caacgctttt
      241 attggcattg acctgagaca ctatgaatct gggaactttc tcgctaagga acacatcact
      301 aaacgaggga atccctatgc cagtaaaatc ttgttcaagt acattcacaa catcgcttca
      361 gctagtcata ccaatccctg caatatcgct gacttttatg agaaacgaac aagacattta
      421 gagctatttc taaactaatc ggcgacccat ctactgtctc taaaaaagta tgtaaacacc
      481 ttaccatcaa ggaatcaatc aacactcaaa atgtgaggcc cgcccacttc taaaacgatt
      541 accttatgtg tgtaatggtt gccctaacaa gtatataaat tgtgacttta ctaagcaatt
      601 ttactacgcc atcggagcta aaattactct gaaaatttac ctcaatcttt tgctaaaaat
      661 cctataaaag agaagcgaaa tacctcctat agataaacca acgataacaa aattaaagat
      721 atttttaggg cttaaaagaa aagtaaatgt cattgtccca atgggcataa ataaaattgc
      781 aacagtaaaa ataatcccaa aaactctacc aagaaagaca ttatccacat tcttttggat
      841 atatgaaaaa aactgtaagt tgaacatagt caaaaacaag ttgaataaag caggatataa
      901 cgcaagcata taagcacttg gaaaaacaca gtataccata ggtgtcaaag atagaaaaac
      961 acctgatact ccaagatata aaatcattgt ttttattttc aaaactttat tgagaatact
     1021 gcttaaagac gctccaataa gaccacctac tgcttctgct cctaggaaaa caccgtataa
     1081 gccaacggta actcttggga acatctgatt gctatatggt aacaacagat tataagctgc
     1141 taaaaagaaa ttaacaatcg cagataaaat aaccaagtac aaaatttcct tttgactagc
     1201 tagatacctt cctccttcaa aaagatctga aaagattttc gataatgaaa acacctgttt
     1261 cccagtactt tcttcaagta tgggacgaat aaagagaata agcaacccag atgcaataaa
     1321 tgttatccca tctagacgta aaataccata taatcctagt aaaccgtata gagataccga
     1381 taccagggga acaacgactt taactaccgt tataaacgat tctagtaatg agtttagttt
     1441 tgaaatatta tctgcttcca ccacttcttt agtaaaagcc ttataagcag ggcctgaaaa
     1501 tgatgagaaa aaagctaata taatgtttgt gataaccaca gcataaatca accactgctg
     1561 attagaaata aaagataagg caagacacaa tactccgctt aaaatatctg ttaaaatgat
     1621 aatccgtttt ctttgaaagt tatcagacag aacaccacca aaaagattaa aaatcacact
     1681 gatgatgttt tctaatgtct gataaatacc aactaacata agtgacttaa catttacact
     1741 cgataaaaaa gtgttattcg caaagtcaaa cataatatct ccaacacgag aaataatacg
     1801 gctccctaca agtaaatatg tattttgttg ttctttttta ttcaaaataa actcctcaga
     1861 tatttgttca ttagcagaac tcttctaacc attgcttcgc aatattatag ttatcctcat
     1921 ccgaaagagt gtttacttgc ttagctatag ccatttctct atcttcaata aacttcttag
     1981 ctgtatatag aatggctgcc tggactaata aaatataatt tcccaaagcg gagtttacta
     2041 caaaattagt tggtgttcct tgatttaaca gatagaaata gttgtcttca ctttcatatc
     2101 tagtgattaa tgaagtttcg actatttctt catattcatc caataaatag ctataattaa
     2161 attcatcatc actagatgtt gcagagacta ggaaggttcc atctttgata gagcgaaaat
     2221 ctaaaatatc tagacttttt gaaccggtcg cacaaaaaat caaatcaata ttcttgaaat
     2281 ctttttctag caaaatgtcg caaccatcac gtaccgcttg aatagttctc atgctatctt
     2341 tttccagcac cttcggtcta ataccaagtt ctcttaattt ggtacagatg ccgtaaccga
     2401 ttttcccata tccaatacaa accacttgca tatattgcat taataaattt ttttgatgta
     2461 atatataatc tgtcccaaaa acaatatccg caccaactaa gtaatcctca ttcttcttca
     2521 ggggatttct agcgacagaa aataacggat attctatttg atcaataaca ttctcatatt
     2581 tttgaatccc attttctgta tcttcaatga tacactcgat aggtaagttt ggaatctgag
     2641 caattgaggc aaaataccca ccaatgtcta ataaaattgt tttactcttt atccccagat
     2701 aatctacatt aaaatattca tcccttgaag ctaatgttaa tcttaccccc atattttcta
     2761 gcttgtgcca taccatctta tcaacagagt ttggtttagc acacactaac aaacgatgcc
     2821 caaatatttt ttgcaatgtc atgataatcg gtattgtact tggaataata tgttgtacag
     2881 taatacatga tatgtcttca aacgatgcac ctttcagcat attagataaa aaacgttctt
     2941 gagaagctgc ttcaagtttt tcaatcttct taatgatttc cttatagccg tccatgtcct
     3001 ttacattatc tagctgaatc cactcatagg aactcgattc gttgctgtca attttcacat
     3061 caacctcatt ttcaatataa aataaatatt gcaagtcata atggtagtgg gaacgctcat
     3121 tcttcaattt attttctggt atcttatgca cagaaacatt aaaaggtatc aagctattca
     3181 atggttctgc acattgatac gtcaatattt cagaatctat cccagtctcc tcaaacagct
     3241 cacgtttcgc tgcatctagc gggtttctat catttttatc aatatgcccc ccaggctgta
     3301 ggtatctttt taaaatatta tggtgaacca tcaataaacg cctgttatct tttgaaataa
     3361 caaatgctga tgctgtaaaa tgcccaatga aattctttct atttatcatc tcttgatcat
     3421 ctttttcatt aagctgtacc aaaacgttat tcaatttatc cttttcctga atattattca
     3481 gttggtaccc ctctactata tctttataaa tactcatcgg tttgtctcct cattttccag
     3541 tcgtttttta tcaattactt ttagctcgaa tttgctatct ttatgcatta agtcataaac
     3601 actattactc aataactcag attttataac tgcgtatgca aatcgctcat gtacaaatac
     3661 attaataaaa tttttatcaa aatcaacatc aattatatta ttaatagtat cttttaacct
     3721 aaatgcttcg ccaatgaaat ttattgatag agacagatta tttaatcgtt cttgcacttc
     3781 tttagcactc atatcatttc ctaacattgc aatttcatag taatcaatac ctgtacgata
     3841 gatctccaaa attttgaaat gagagttttt aaactcctca aaagtttcag ttcgatttac
     3901 ttggaatgga attttcttgt gaatgtctcc tattaagtca tacgcatcaa actgttcata
     3961 atctctaaaa tccaaagata gacccccaga tatagcagac agattatagt cgcttaaaat
     4021 acactgtgag atagcataaa ttgtaaaaag atatacatcg tctcctttaa tatcttctgg
     4081 taaagaaact tgaaaacatt gaacttcatc atttaatttc tcaaactcaa tagcaggctt
     4141 tatctttggc aatctagcaa gaacatcccc agagacatca ttctgtaaca cctccctttt
     4201 aaactgcgaa aaagcaacca gtgaactact aggtacttca tcaataacta tctttttttc
     4261 gtacagttga tatactgtat ctccaagttt atttaatgat gatgcatcaa tagaatgata
     4321 tggaaaataa aatcttactt ttttatctct tgttcccacc acaataattg gaataggaat
     4381 cacttctata ttatctaata ttccttgtaa ttctaactct gttggtaaat tatttagtac
     4441 aataatatta ggtgagtaat ctccttcatt cacaatacct atgctaaatc gagtttgctc
     4501 cttttcgaca acaagtctaa atatatcaat tttatagctt aaatatttaa taatatggtg
     4561 cagcttattc aattctaaat aagtcacttc ttccagtgct aaattaaaac caataacacg
     4621 attttgattg tttttataaa gtctcttttg tgtcgggcta ggagtaataa tatttttcaa
     4681 ataacgataa ttcatttttg tgagattata ctctaaatta accaagtcat gttctttagt
     4741 aaaactatcg tttggctcag ttgaacgttc ttgaaaaaat gatttatttc taatatagtc
     4801 cacaatcgaa tctacactct ttagcctata aaaatcattt tctttaattt caatatcaaa
     4861 gatatcctca atctctaaat aaaatctaac caattctaac gaatccaaat ctgtgatatc
     4921 aactctttca aatttagata gtacatctaa aatatttttt ctaacatcat ctccttgttg
     4981 actttgtttt ttataataat atatctcaag catttttgga acatccaact ttctattctg
     5041 attgagataa taactctcaa ctttaactac cgtcggattt aagtaactag gtaaacttct
     5101 aataatatct tctttaatat tcaaatcggc ttcataaaat acgacaagtt tcttcttata
     5161 aaaaacaact cgtgatgatt taactgtttt aagtttatct acaatagatt ttacctcatc
     5221 taattcaata cgaataccat ttacttggac ttggctatct attcttgaac taaataccaa
     5281 gttatctcct tggtaataaa cgtagtcccc cgttacatag tacctatttg aacctatcaa
     5341 cttaaactta gctttattta attcgggttg tagtctatac ccttccgtta ctccattacc
     5401 accaattaga agttctgcca tcttagaatt ctctttttga gaagctatct ttagttgaac
     5461 cccaggcaaa ggcttaccaa ttggaacagt attatatttt ctatctttca actcatagta
     5521 ggttgcataa attgttgttt ctgaaggccc atataaatta aatactcgac acccttgctg
     5581 aataagccct ctcaacctat tcgctaatga actaggaaat gtctcacctg ctagacacaa
     5641 cgctcttaaa ttctggaata cttctggccc actaatatca ataatagttt cagcaaaaga
     5701 cggagataat gataaatgag ttatcttctt ttgctcaatt gtttctccta gtcgaataat
     5761 attctgaatc ccaccatcgt aacaaaccaa agtaccaccc gtatatacag gtgccaaaat
     5821 ctctgttaat gaaacatcaa aagtataggg agttgtaaat aaaaattttg attcggaagt
     5881 aaacttcaca attttataaa attcttttac aagccaatct atgttatcat cagttaaaaa
     5941 tactttttta ggaaccccag tagttccaga agtacagata atatgtgcaa tttcattctc
     6001 tttagttgta gctacttctt gatactcact gtaactttct aattttttgg gtaagaccaa
     6061 aagagttact gaatgatttt caagtttaac atccctatca cttatcaaca cgtcaaagac
     6121 aacttcgcta atacgttcta atgatatttt gacctcaaga ctatttgtta taggtaacgg
     6181 aattttaccc gatttcatta tccccaaaac aactggtaaa acatacttat ttttttctat
     6241 ataaaaaggt acagtctctt catcgctatt gagtagtagc tgcttagcaa taaaattaga
     6301 catcacatct acttcttgaa aagtaaactc tcctccgcta tacataacag caactttaga
     6361 aggatattgt ttcaccgtat cactaaaagt ttttaatatg gtcatttctc ttctccttaa
     6421 tttgattgat tatgcactgt cattcataat ttatccacac acaacaataa gaatttcaaa
     6481 agcaattttc aaagttggca aaaattttac ctttttcatc atttccctct tttgtttatc
     6541 atatgataaa caaaggcttt tcgtcaccca ctacagttga caaagagcct ttcttatttt
     6601 ttacttggaa ctttcaaagc gtctttagtt ggaatataat ctttatttcc aaagaatttt
     6661 tcagccaact tagccaaagt accatctttt tggagttctt ccaaacgt
//
