LOCUS       gnlProkkaKMFBCEDI_51    8952 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KMFBCEDI_51.
ACCESSION   gnlProkkaKMFBCEDI_51
VERSION     gnlProkkaKMFBCEDI_51
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 03:44:08
            Original ID  :: gnl|Prokka|KMFBCEDI_51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8952
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..612)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_1"
                     /sec_met_domain="Polysacc_synt (E-value: 5.2e-19, bitscore:
                     57.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSS"
     protocluster    1..8952
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[954:5268]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      955..5268
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..8952
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8952
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(815..958)
                     /locus_tag="ctg51_2"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             complement(955..2076)
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg51_3_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_3"
                     /sec_met_domain="Aminotran_5 (E-value: 9.5e-32, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        complement(979..1986)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg51_3_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg51_3_Aminotran_5.1"
                     /locus_tag="ctg51_3"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             complement(2086..3210)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.7e-21, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.8e-21, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             complement(3227..4528)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.2e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.3e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.4e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(4549..5268)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_6"
                     /sec_met_domain="NTP_transf_3 (E-value: 1e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(5332..6480)
                     /locus_tag="ctg51_7"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(6491..8902)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg51_8"
                     /sec_met_domain="Poly_export (E-value: 6.7e-19, bitscore:
                     56.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
ORIGIN
        1 agaacttttg gagaaagtat gtaaaggttt ccaatgaact aaacagtaaa acaaaattgt
       61 caaaattata ctatttaaga gagtttgcca aactaaagcc caaaccccgc aaccgacata
      121 agccatccat attccaatca cgcctgatat aaaagctgca cctaatgaaa ttttagattg
      181 agttttaaag tttacagaaa taattaattt cgttctgtga atagccgata aagcatttat
      241 tatcaacgac aatgctataa aacgaattac aagaactaaa gtcggcatat tataaaagtc
      301 tgcaatcaaa gaagccgaaa aaaacaatat accatagaat aatactgcga caagaatatt
      361 aaaataaaag acagtggcaa aatcctcttc agttctatct tttttctgga ttaaagcatt
      421 tgtaaaaccg ctatctataa atacttgagc gacttgaaga aaaatagcta acatcccgat
      481 cataccataa tccgatggta gtaacaaacg agctaatatt atttgaatta taaactgtac
      541 tccttgtaaa gagaaacgtt ctatagcgct ccacattatt cctgatacag ttttctgctt
      601 tagattttcc attacttaaa tacagtataa aaacaactac atttaccgat atcaattata
      661 tttttccaat attctcacta attggttatt atcttcttcg ccccttaccg caattctaat
      721 atggtctctc ccactaaaag caaattaccc tacacaaaca ttatctccta taactaccga
      781 tgccttttta taagaataaa gaactcctaa tgcatcacct caaattaata ttgccatatt
      841 tgcctactaa gcgaaagcta cgaataggca ctccagaaat aacactttcc ggatggaagt
      901 gtataccacg aagggaaaaa taaaaatgac gaatcttcaa taatatttct gcaatcatga
      961 catcggtaat gtgacgttat aatgatttaa tgcagctttt agtactttaa agaagttctc
     1021 aatatcatct acttctatct ctcctaaagc acagattcta aaagtatcct cagttgatat
     1081 cttacctgga taaatcgtaa atccacgctc ataacaataa tcatgtattt tctcaaaatc
     1141 ccagttggga tcttctgggt attgaactga gacaaccagt cctgactgcc attcacgctt
     1201 tattacactt ttaagaccaa tttcatttat acctgaatga atagcctcaa aaactctttt
     1261 gtgacgggca aacttagctt cttcacccac ttcaaaatat tcatttaatg cctgacgagt
     1321 ggcgtaaata gtttgtaccg gtggagtaaa atgcatttca cctgttctct caaaattctc
     1381 atactgcaaa taaagattac aatagtaaga acgcttggga tatttttttg aaaacttaat
     1441 ctgttcctca ttgcctataa taaaagaaag acctgtcatc gcttgaagtc ctttttgagc
     1501 agatgccata caaaaatcca cattatcttt ctctatatca aaaggaatca tgcccaaaga
     1561 agaagtagta tcgacgacaa atttagcctg atatttatga gctatagcgc ccatctcgcg
     1621 aatagggttc agaattcctg tacccgtctc gtgatgagta gtataaacca tagctatatc
     1681 aggattttct tgcaacacat tttccaccac cgataaatca ggacgttcgt aaacggaaaa
     1741 ttccaaatta atatgaggca aaccataata ttgacacact tctacagcac gggtactata
     1801 tgccccatta ttcactataa gcaccctttt gtcttcagga agaagagaat ttagacatat
     1861 atcaatattg atggttcctg agccacaaaa taatacagcg gtatgttttt ccaaattccc
     1921 atgagcaact ctgaccaaat cgtcccgaag ttgtttcatc atacctgcga attctttctc
     1981 gcgaggacaa atatccggaa caacttgtgc catttttaca ctgtcagtag tagtggcagg
     2041 cccaggattt aataatattt ttctttctat tttcatcgaa tatatttatt ttaaaaaatc
     2101 cataaaatgc tccttattct ctataggagt agtcgtggga cgtcccaaat tctcccgaga
     2161 atctatttta acctttattt ccaacaaaac aggaccacat aactttggaa gctgcttcat
     2221 tgcttcttca atttcaactt ttgtacaaac agtataagta tgcttatatc cgctcccccg
     2281 gacaatagcc ggaatatcta aactaaatcc taaagtaggc tgtcctccta cagactcgtg
     2341 agcaccattg ttaaacaaaa tatgataata gtttttagga gataaatcgc caatgttact
     2401 aattgcccct aaatgcataa taaatgctcc atcaccatcc aagcaataaa caggtctatc
     2461 ttgctttgct atagcaatac ccaaagagat tgatgaacta tgtcccatag agcctaccgt
     2521 gagaaaatca tgttcatgac cttgctcttt catttctcga tattcaaata actcacgaga
     2581 aagcttgcca gtagtagaaa cgaccactga attttcaggc agataatcca caactatttg
     2641 caaagcatcc tcacgagata aaggataatt acatccgaac tctttttgaa gtttatattt
     2701 gccaaaaaca tctttccgaa taattattgc atgaggaata ttcttagttt ttgctgattg
     2761 tatgatatca tggagctgaa taaatgcatc attctcattt gaatcaagaa ttatataagg
     2821 aatccgcatt gctttcaaca aatctaaagt tacctcaccc tgttttttat gctgaggttc
     2881 atcttttgtt cccggttcac cacgccagcc aatcatcaaa agcattggaa aactgtatac
     2941 ttgttcatct gcaagagaca gcagaggatt aacagtatta cccaagccgg aattttgcat
     3001 ataaaccaca ggaaccttac ctgatgccat ataataacct gaagcaattc ctacagccgc
     3061 accttcatta gcagctatga tatgtttctc acgtgaagta tggtctgtga tataggcaca
     3121 aatatttttt agtaatgagt ctggaactcc tgtaaaaaaa tcaacgtcat gactcagaaa
     3181 cgtttcataa actttttcta cgcttaacat aatgatattc ctctttttat ttagtacctg
     3241 gaatcagttc caatatttct tttatgggca tacacagttc gcgcacctct aaagcacgtt
     3301 cattctctaa tattatcttt gcgacattca tcatagcagg ataagcggca cgaagcatat
     3361 gattagcata aataattata ttcacacccc aatcacacaa ttcagactca taaatatgat
     3421 catatgtagt aggcacaacc acgataggta catgagcata ctgttttcga aacgccaaac
     3481 aaaattcttt tatatcttca cccgacttat ttttgctatg tatcataata ccgtccgctc
     3541 ccgcttggac atatgcaaaa gctctctcta aagcatcact taccggcttt cccgctataa
     3601 ggctctcaat acgagcgata atcataaaat catcagtaat ctgagatgcc tttcctgctt
     3661 tgatcttatt acagaaacct tcgattgtat cttgagtttg aataacatct gtaccaaaca
     3721 atgaattctt ttttaatcca actttatctt caattattat agctgaaatt ccatgacgtt
     3781 ctaaagtgcg tactgtaaat acgaaatgtt caattttacc acctgtatct ccatcaaaaa
     3841 taataggttt agtagtacac tccagaatat tattcaaatc ttgcaatcgg gtagttaaat
     3901 caaccgcctc aatatcaggt ttacctttac tggttgaatc cgtaaggcta ctagaccaca
     3961 ttccgtcaaa tacttccctc ttatcccctt ttaatatttc ctgattttca attatcaagc
     4021 cacatagtcc atcatgagct tccaaaatac gaactacggg tttggcattt atcaaacgac
     4081 gaagtgattt taaacgtaca tcaggggttg tacctatagc cttaatatct ttatccaaag
     4141 aagatgaatt aattcccaaa gtatatggaa tttcgataac ctttcctccc tgttcattca
     4201 tcacttcaaa tacgcgcaca cgttcttcac gtaaaggccc ggttttccag tcgtcaccat
     4261 gaattatata gtcaggttta atgcgtttga gattctcaac atagctccat tcttcttgag
     4321 gaacaacttt acatacgcct ttaatattct gaactacctc ttttcgttgt tcataggtca
     4381 gataaggaag gcgtttatgc tccgcaatag ctttatctgt aagaagacca attataacat
     4441 caccgtattt agtagcctca ttaataatgc ggataagtcc tggatgcata atatccgcag
     4501 tcatcccaat ataaactgtc ttactcataa tttgatatat tattttaatt aacaatacgg
     4561 aacaatatat ttctctgcat attccaaatc tgatatgtca tcgatttcat accatttcag
     4621 cccttctact ttatgcacat aaacaggaga ttgagaacaa gatattcgta gtaattcata
     4681 ctcatatccc aaattgggtt gttcatcaac aatactcgca taatcagcac acattatttt
     4741 gtaaaaggaa ccggatagtt tatggatgcc gaccaattcg cctttagcgt ttagtttatt
     4801 cttattgaca gaacatgaag aaaggcgaaa attatcatca tgttccacat aatactgatc
     4861 ttgaaacttt gtcactggag ttattagcat tgcatctgcc gcaggacact ccaataagct
     4921 cattattgct tgtttctcaa aaatcaaatc tgactctaac aataaaaaat catcattgcc
     4981 cagaatctcc cgcgtattat ataaagtata catactattt gtttcagcat aacgaggact
     5041 aaaacaggtt tcaagcatag gatagtctgt cttcaattct tcataaactt cttgtttata
     5101 tcctgtaccg attacaattc gctcaatgtc acatgataac aaagtatcaa tagaacgaac
     5161 tatcattgga atacctccca ctttgacgaa ccctttaggt atcaattctg tatattggcc
     5221 aaaacgggtt cccatgcccg cagccattat catagctgta cgtatcattc gtttaataat
     5281 atagtaagtg aatttaattg atgtaagaat gttgtaaacg acgttttagc atcatttatc
     5341 ctgttctatc tccttatttt tcagttcttt tctcaagcta gccagcagac ttttgccaaa
     5401 aaacacccac acgagagtac cagatacgga caggaacaca aataataaaa tataaatttt
     5461 gagtcccata cctgaaggtt tcaaaggtac aacggcaggc tcaactactg caaagactgg
     5521 cttttcctcc tgtactttgg ctctggatac ctgcaactga ttagcaacct gactatatat
     5581 ctgataagcc aaactcatgt cgttctgtaa acgctcctgc tcagcacgta cactttgaag
     5641 aaccacatta tcatgggcgt ctacataatc cgcatatttt ctttgagcag cataatattc
     5701 ctgctgacgt tctttaaaca accgttccaa atacgcacag tcttctttta cttttgaagt
     5761 tcgataccca ataatatatt cctgtaattt atgaacgaca gaatctgcta taaccgcagt
     5821 gatctgcgga ttttgtaagg tgaccgtaat gctcgttatg gcggttttct tatcaatgga
     5881 tgcactaatc ttctttttaa gaaaattaat cttctcattt acttctttcg tcaattcgat
     5941 agttccttgc cgccctccac tggcaggaac cgtatcttct ccgaataatg atttaactcc
     6001 tcctattact atgcccggaa aacctataag ataatcccac caaggagatg actcttcatc
     6061 gagataagac cccaaagtca ttttatcatc ctttttagaa acggagactt ccatttctaa
     6121 aagttccaat aaaaaaggag ttgaagaaac aatatctgct gaaagagaag cgttcaaggc
     6181 atctgtgctt tcccctatta gagccccatc tcccaaaaac gaggcagcaa gtccggctaa
     6241 accattactt cccttcgcat tacccatttc aggagaaagg gtaaccttta ctgtatattg
     6301 cttgggaatg ctcaatgcca ccactatagc aattattact cccactccag cagctttgca
     6361 tagtactcca cgaacagtaa taatcttata aaaaatagcc atcaagtcta tttccatttc
     6421 atcatctttc cttttatcca cttcagaaaa cggttcttga taagattgct tttcaatcat
     6481 aataggtcat ttatttcttt atcaaattag caatagaagc aatcatcatt cccaaagaac
     6541 tgaaggaagt agcataacct aaaatattag ctatgttccc tttcttctta gccttaccag
     6601 gcacaataat ctcacacccc ggctcaatct gtttcttacc actaccctta accttcgtca
     6661 cctgaccatt catgtaaaca atgaacttct tactcttcct tgcattatca gaacagccac
     6721 cggcctgatt caggtaataa tccacattct ttcccttcat ataagaaacc gtattcggaa
     6781 ccatgacagc accattgata gttacagtat tagtattctt aggtatggag atcacatcac
     6841 cttcacgtaa gacaagatcg gcattacttt taggattgct caaggctttt tccaaatcta
     6901 ttccaaccgt aaaagtatct tcaacacgaa tacccaaaga gtcaatcatg gcttcgccca
     6961 attgcctgct cataaggcga attacatcac ccatacgttt cttttcacta gcgttagcca
     7021 cacgggtcag tttcgcacca cgcagatagg cataattggt cggaccgccg gctttattca
     7081 ctaaatcgga aagacgttcc tcacggctgg tcatggcgta atttcctccg aaaaggattt
     7141 caccttcaat ggctacattc tgttgtgcct gatagcccgg actgcgacgg acataaacct
     7201 gatcataagg ctcaaggata aaaccgggct gaccatctat tacaaaacca tcctttaaag
     7261 agaaggtata catctgacca atcgtatcat tatccgcagt actacgagga ttcttgattc
     7321 gtctcgatat atcaatacgg acagtagagg cggcttcttt caagccaccg gcctgaatga
     7381 tcagatcctc aagtgtcatg ttatccgcat aaggatagga atcagggtgg gcaacctcac
     7441 cgtgaactgt gacattaccc cggtcttcca ggtcatggat acttggaatg tagaggatgt
     7501 cattcttcat tagggcaagg tttggggaag tgccgtccat gatagactta atgtctatct
     7561 gaacaacttc actggtcagg tcttcacgct ggcgatagag gacggcacga ttcaggaaag
     7621 cgtcaccggt cagaccctga gcttcatgga caagttcgcg gatcgtgttc agtttaccgc
     7681 tgagctggta gataccggga cgatagacag cgccacggat ttccagtttg tttgtgaagc
     7741 ggttaaggat ggcttcggcg gttactacgt caccgttacg cattttataa atgttgtaat
     7801 ctatatcttt gactgtgttg acttcgtatt cctcaccatt ctgacggaca acacgtaatg
     7861 aacgggtgta ggcatcagct tcaaagccgc cggcatattt aatgagagta gcaaggttct
     7921 cgtctttctt catttcaaaa cgcataggac gttttacctt gccgctaatc tttaccaata
     7981 catcataggc aggaacaatc acaacgtcac cttcctgtag gcggatgtca tcctgtgtgt
     8041 tgcctttcat aatgaattcg tagacgtcga tggtggcaat attctttccg ttgcgtacca
     8101 actgaacgtt tcggaggcta ccgatatcac tcacaccgcc tgcacgataa agcgcatgga
     8161 agacggtaga gaaggaagaa agggcgtagg taccgggctg tacgacttct cccatcacat
     8221 taatctgaat agtacggata ttacctaacg tcagacggat gtcggaagta ggatcggtag
     8281 tattattcag accgttatat attttattca gggcgttctt cagatagtca ttggcggcag
     8341 agactgtcat accgctaagg ttgacaggcc cgatcttctg aatgttgata gtaccttcag
     8401 gagagatttg ctggcggatc gtgttctggc tcgcacccca gatatcaatg atgacttcat
     8461 caccgggacc aagacggtaa ttggcaggag tggcaaggtt gacactaggc tcgaacgtca
     8521 ggttgcgggt attgaagatg ttacgtccga agacctgatc accacgggca aggtcctgag
     8581 tagtcggatg atcctccagc atatcggaag tattcttctt agtctcttca cgcaggcggg
     8641 attcgttgat gtccgtgccc gttgatttcg aggtatttac attgttctgc tgctcgtata
     8701 gctgcttcac acgcattgcc tgttctttgg ttacaccctt acgggctagt tcggaagcaa
     8761 gctgcttctg ttccttgcct tggcggatgc cgtcttttac atattccagt acctgtgagt
     8821 cactcatgga ctgagccata agcgagccac ttcccagcat caaacaaaat agtagaatgc
     8881 taaaaagtcg ttgtattttc attgacaaat aaaaaagttt cagttgattt cacacagttc
     8941 ctgcatccca tg
//
