LOCUS       c00042_gnlPro..        16475 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LFAKPPKH_45.
ACCESSION   c00042_gnlPro..
VERSION     c00042_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:36:50
            Original ID  :: gnl|Prokka|LFAKPPKH_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16475
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16475
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3036:6594](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3037..6594
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16475
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16475
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(464..1618)
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1798..3003
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3037..6594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6719..6907
                     /locus_tag="ctg42_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6918..7778)
                     /locus_tag="ctg42_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7806..8636)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8633..9859)
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10332..11618
                     /locus_tag="ctg42_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDREFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11581..11913)
                     /locus_tag="ctg42_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(11941..14694)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15027..16253)
                     /locus_tag="ctg42_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNRSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 aatagttgta ctgctttttc gaatatttca tctttatttt cgatttttga agtgtcaact
       61 tattcagtac actacacgaa actatctgaa actactgttg atttgattga cttaaccgca
      121 tgttccaatc acattgaacg catcagctac ttcaatagta ctgctctctc tgaaaacatt
      181 aaatcatata tcagtcaata atacataaat tatcagtcct taatacttga tttctcaatt
      241 attaatatct gagaaatcaa acgttaacag ttgagatatc agatattaac atcctgtaaa
      301 tcaaagaata acacagtaaa aacggtattt atcaggacga tgcagagtga gagcaagtcc
      361 ttgctctcac tctgctacca ctggatctct aacagctaaa acatcgatga ataaagggat
      421 acagacgaac tgttagagca tgagagcaaa agcactatct ttttcactgg gggagagtaa
      481 gcaaaagaaa cgcacgatac cggctttgag gcgtcaccgg tactaacggc aaatatccgg
      541 cacacacccg attattctct acggacaaag ggaacgaagc cgacatctgc cgatgttcct
      601 ccaaagcctg accggctaaa ggataataat caatccgaaa aactccttcc gcatccgcag
      661 ccaaataacg atccgtcaag agccatgcca ccacccccat attcattcgc agattaattt
      721 cgacacaagg atgaatccgg taaacaggcg cttcatccgg aaaatgacaa atcatcatat
      781 ccactcccaa gtatccatga taaaagccac cgaacaaagc tgacaattct tcttccaaac
      841 gagtccgcag cctgataaat tcttcttgtg gcacataagc cgatagtttc tgcagaatct
      901 tctcgtcaga cagcaagtca ttccctgcat acatcccact cccacccgtg tggaagaccg
      961 aatatccggc aaaaacaacc cttcctctcc cgtcagcata aaactccata gcgaaatctt
     1021 ccaccttatt atatataggt tcgcctacca ccccaccctg agaagcagcg acacgggcac
     1081 accaaccgga aataaaagta gtaaatatgc ctttacacca attcaatcct ttcccgcttc
     1141 cggaaagcgg agcttttaac aagcacgctt cccgcccttc gacgaacgca ctgcactccg
     1201 ccaaagtact caaataaaaa gattctccac agaagtattc attcaaccgc aacccaggca
     1261 acaactttac cgcctgcaga cgatgcgaat gctctctcag aatattcata taatccgcag
     1321 aaggcagctc cgtctgacct gcccccaatg tcatcaaacg cttccgcaaa gcagggtccc
     1381 aaccccacgg agagaacttc cagtctttac cgtcagccac ttccggttcc gtcaacaagg
     1441 ccacatccat gcccaaaagt tcactctttg ttttcaggaa gtccgcatta taagcagacg
     1501 gtgcaagcac cgcacttccc gcttcggcat accacatagg aagcaacgcc aggtcactcg
     1561 ccatctgtcg ggcggaagcc ggcgccatat agttcgtctc accgcttgcc aacgccatat
     1621 catgctccgg attgaatata taaacaggtc ttttcgtcat gtcaaagatg gattcaacac
     1681 attattctgc aaatatatac aggaaataat caggaactta cacaataaag agaaacttat
     1741 aaattaaagc acatttttgc tatctctact ttgcaaatcc taaaaaaagc actatatttg
     1801 ccagccgaaa aacaaagaaa cgaaatggaa tcattctatc gcacacacgc ctacctcgtt
     1861 gagcacacca atgcccccgt tcgccgcgat cttatggacg agatcgactg gagtgaccgt
     1921 ctgattggta tcaaagggac acgtggcgta ggaaaaacca ctttcctcct gcagtacgcc
     1981 aaagagaaat tcggcaccga ccgttcctgt ctgttcatca atatgaacaa cttttatttc
     2041 tccggtcaca gccttgttga cttcgccaac gagtttcaga aacgtggcgg aaaagtactg
     2101 ctgatcgacc aggtgttcaa acatcccgaa tggagcaaag agctacgaat gtgctatgac
     2161 cgtttcccca gcctgaagat tgtcttcacc ggttcttccg tcatgcgact caaagaggaa
     2221 aacctcgaat tgcgtgacat tgcgaaaagt tataacctgc gcggattctc tttccgtgaa
     2281 tttctgaacc tgcagacagg aatgaaattc cgggcataca gcctcgaaga aatcctcagt
     2341 acacatgaac agatagccaa aggagtactt tccaaagtac gaccgctgga ttattttcag
     2401 gattacctgc atcatggttt ctaccctttc ttccttgaaa aacgtaattt ctcggagaat
     2461 ctgctgaaaa caatgaacat gatggtagaa gtggatatct tgctgatcaa acaaattgag
     2521 ctgaaatatc tttcaaagat aaaaaaatta ctatatttgt tggctgtgga cggaccgaaa
     2581 gctccgaacg tgagccaact ggcaagtgac gtacagacat cccgcgctac ggtaatgaac
     2641 tatatcaagt atctggcaga cgcgcgtctg attaatctgg tttacccgaa aggagaagaa
     2701 ttcccaaaga aaccgtcaaa gattatgatg cacaactcta acctgatgta ctccatttat
     2761 ccggtgaaag tggaagaaca ggatgtactc gacacgttct tcgttaacac tttatggaaa
     2821 gaccataagg tacataaagg agataaaaac gtctctttca tggtagacga agtgatgccg
     2881 ttcaaaattt gtgcggaagg tacaaaaata aagaataacc cggacgtgac gtatgcgttg
     2941 caaaaggctg agataggccg cggcaaccaa atacctcttt ggatgttcgg attcttatac
     3001 taaaaagatt tatttactta aatatttaat ttagttatga ctaaacagaa gaaattcatc
     3061 acatgtgatg gtaaccaagc tgcagcacat atctcgtata tgttctctga agtagcagct
     3121 atctacccca tcactccttc ttcgactatg gctgagtacg tagacgaatg ggctgccgca
     3181 ggacgtaaga acatcttcgg cgaaacagta ttggtacagg aaatgcaatc tgaaggtggt
     3241 gctgccggtg cagttcacgg ttctcttcag gctggtgcat tgactactac ttacactgct
     3301 tctcagggtc ttcttttgat gatccctaac atgtacaaga ttgccggtga attcttgcct
     3361 tgtgtattcc acgtttctgc tcgtacactg gcttctcacg cattgtgtat cttcggtgac
     3421 catcaggacg taatgtcagc tcgtcaaacc ggcttcgcta tgttggcaga aggttctgta
     3481 caggaagtta tggatttggc aggtgttgct catctggcta ctatcaaatc acgcgttccg
     3541 ttcatgaact tcttcgatgg tttccgtact tctcacgaaa tccagaagat cgaaatgttg
     3601 gaaaacgacg acctcgctcc gctgatcgac caggaagctt tggctgaatt ccgtgcccgt
     3661 gcactgaatc cgatgaagcc ggttgcccgt ggtatggctg aaaaccccga ccacttcttc
     3721 caacatcgtg aatcatgcaa taactactat gaagcagttc ctgctatcgt agaagaatac
     3781 atgaacgaaa tttccaagat cacaggccgc aaatacggtt tgttcgatta ctacggtgca
     3841 gaagatgcag aacgcgtaat tatcgcaatg ggttctgtaa ctgaagctgc ccgcgaagct
     3901 atcgaccact tggtagcaaa cggcgaaaaa gtaggtatgg ttgccgtaca cttgtatcgt
     3961 ccgttctctg ctaaacactt cctggctgct gtacccaaga ctgcaaagag catcgcagtg
     4021 cttgaccgta caaaagaacc gggtgctaac ggcgaacctc tttaccttga cgttaaagac
     4081 tgcttctatg gcgcagaaaa tgctcctgtt atcgttggcg gtcgctacgg tctgggttca
     4141 aaagatacca ctccggcaca gatcatctct gtattcgaaa acttggctat gccaatgccg
     4201 aagaaccact tcactatcgg tatcgtagac gacgttacgt tcacttctct tcctcagaaa
     4261 gaagaaatcg ctctgggcgg tgaaggtatg ttcgaagcta aattctacgg tctgggtgct
     4321 gacggtacag taggtgccaa caagaactct gttaagatta tcggtgacaa caccgacaaa
     4381 cactgtcagg cttacttctc ttacgactcc aagaagtcgg gtggtttcac ttgttctcac
     4441 ttgcgtttcg gtgatactcc gatccgttct acttacttgg taaatactcc gaacttcgtt
     4501 gcttgtcacg ttcaggctta cctgcacatg tacgacgtaa cacgtggttt gcgtaagaac
     4561 ggttctttct tgctgaacac catctgggaa ggcgaagaac tggctaagaa cctgcctaac
     4621 aaggtgaaga aatactttgc acagaacaac atctctgtat actatatcaa cgcaactcag
     4681 attgcaatgg aaattggttt gggcaaccgt accaatacaa tccttcagtc tgcattcttc
     4741 cgtatcacag gcgtaatccc tgtagatcaa gctgttgaac agatgaagaa attcatcgtt
     4801 aagtcttacg gcaagaaggg tgaagacgtt gttaacaaga actacgctgc tgtagaccgc
     4861 ggtggtgaat acaagactct gactgtcgat cctgcttggg ctaacctgcc ggatgatgca
     4921 aaagcagaaa acaatgatcc tgctttcatc aacgaagtag ttcgtccgat caatgcacag
     4981 gacggtgact tgctgccggt atctgcattc aagggtatcg aagacggtac ttggtatcaa
     5041 ggtacttcca aatacgaaaa acgtggtgta gctgcattcg ttcccgaatg gaatgctgaa
     5101 aactgtattc agtgtaacaa gtgtgcttac gtttgtcctc acgcttctat ccgtccgttc
     5161 gtactcgatg ctgaagagca gaagggtgct aagttcgagc aactgaaagc tgtaggtaaa
     5221 gcattcgatg gtatgacatt ccgtattcag gtagacgttc tcgactgtct gggttgcggt
     5281 aactgtgccg acatctgtcc gggtaatccg aagaagggtg gtaaggcatt gaccatgaaa
     5341 caccttgaaa gccagttggc cgaagctgat aactggactt actgcgctga aaacgtgaag
     5401 agcaaacaac acctggtaga catcaaggct aacgtgaaga actctcagtt cgcaactccg
     5461 ttgtttgagt tctcaggcgc ttgctccggt tgtggtgaaa ctccgtacgt gaaactgatt
     5521 tctcagttgt tcggtgaccg tgaaatggtt gctaacgcta caggatgttc ttctatctac
     5581 tccggttcag ttccttctac tccgtacact atgaacgaaa agggtcacgg tcctgcatgg
     5641 gctaactcct tgttcgaaga cttctgtgaa tttggtctgg gtatggaact ggctaacgaa
     5701 aagatgcgtg cccgtctggt gaaagtaatg aacgaagcta tcgcttctga ttgctgcccg
     5761 gctgaataca aagaagtatt tgctgaatgg atcaacaata tgctggatgc agaaaagact
     5821 aaggaactgg ccgaaaagat cattccgatg gtagaagctg ctaaagataa atgcaaccac
     5881 tgcaagcaaa tcgctgatct gcaacaatat cttgttaaac gcagccaatg gatcatcggt
     5941 ggtgacggtg cttcttatga tatcggttac ggtggtcttg accatgtaat cgcttccggt
     6001 aaggacgtta acatccttgt attggatact gaggtttact ctaacacagg tggtcagtct
     6061 tctaaagcta ctccggtagg cgctatcgct aagtttgctg ctgcaggtaa gcgtgtacgt
     6121 aagaaagacc tcggtctgat ggctactact tacggttatg tatatgttgc tcagattgct
     6181 atgggtgctg accaggctca gactctgaaa gctatccgtg aagctgaagc atatccggga
     6241 ccatcactga tcatcgctta cgctccatgt atcaaccacg gtctgaaagc cggtatgggt
     6301 aagagccagg aagaagaaga aaaggctgtt aagtgcggtt actggcactt gtggcgttac
     6361 aaccctgctt tggaagaaga aggcaagaat ccgttccaac tggatagcaa agaacctaac
     6421 tgggaagact tccaaggttt cttgaagggt gaagttcgtt acgcttctgt aatgaaacaa
     6481 tatcctgctg aagctgaaga actgtttaaa gctgctgaag aaaacgctaa atggcgttac
     6541 aacagctaca aacgtcttgc cagagaaaac tggggagctg atacagctga ataataagta
     6601 gaaatacttt gtacataata aaaggcagga atcctggaaa cagattcctg ccttttttgt
     6661 ttatatctta gaagtaacga ttacttctca cgaagatatt cattaaaact ctaaagatat
     6721 gatcggattt gttatttgga ttatcggttt gatactgact ttcagagctg ccatagagat
     6781 ttggaatata aatgcggctg tagagaaaag acttatagcg attgtattaa tcgttcttac
     6841 cagctggctg ggactacttt tctactactt ctatggtaaa gaaagaatgg cgggatggtt
     6901 gaagtagtgt ttgcatatca atctttctca ggaatccaac tgttcaccag ttcctgatgt
     6961 tcttccatcc attgacgggc agcctgtctt tccgttgtct gcgcctcttc cagagcagtc
     7021 attaaggagc tgatttccgc atctgtcaga cgaatgttgc ccaaaagttc ggcagcaaaa
     7081 gggtctttct cgctaaaacc tttccatgct atggtatgaa tggattccgt atttccatat
     7141 atcagcttcg ggtcctgaag aactttcagc ttgaaacggt cgaacatcca gtgaggcgtc
     7201 catcccgtca cgacaatcca gtctttctta tcaatcgctt tctttaggga agcagtcatg
     7261 gcaggtccgc tcgaagtcat cagtttataa tccaatccat agtctttgat ggcctgatcg
     7321 gtagctttca taataccggc tccggcatca ataccgacaa tctgaccgga gaaacgttcc
     7381 ttttccgcgt tcagttcttc gattgagttg atcgtaacgt aatccggaac caccagcccg
     7441 atacgggcac catcataaat atccccgata acttcgagtt tatccccgta ttgtttcata
     7501 taatcttcca tagtgacagg catccagaca tccataaata cgtctgcttt cttacgggag
     7561 atagaggtaa atataggtgc aaggtcggca ttcagcaact ttacatcgta cccctgatct
     7621 tcaaaaatcg ctttggcaag gtttgtcatt gcaatacctt ccgaccagtt ggcataagcg
     7681 atacttatct tcttactctt tccgttgtct ccgcaggaaa cgaaggttaa gagtatgccg
     7741 gcaataaaca ttgccgcaat catttttatc ttattcattg attattcctt tctttggtgt
     7801 gattcttatt tctttttact ttttctgtta tctgccatac cctgagtgat gcggtccagc
     7861 acgatcgcca atatcacgac tgcgataccg ccttcaaatc cgagtccgat tttcatttgg
     7921 gtgatacctt tcagcacgat ttctcccaat cctccggcag aaatcatggc agcaatcact
     7981 accatcgaaa gtgacatcat gatcgtctgg ttgattcccg tcagaatagt aggcaacgcc
     8041 aaaggcaatt gcaccttata aagaagctgc cagggagtag ctccaaaaga gcgggaggct
     8101 tctactacgt ttttaggaac ctgacgaatg cccagaccgg tcagacgaac cacaggaggc
     8161 attgcaaaga tgatggtggc aaaagctccc ggcacagttc ccaatccgaa gaatagaacg
     8221 gcaggaatca gatagacaaa ggcaggcatt gtctgcataa agtcgaggac agggcgcatt
     8281 atcttgttac aacgatcact gttggcagtc cagattccca acggaacgcc taaaagcaat
     8341 gccagacaag tggaagaaag taccaatgcc aatgtctgca tcgtttcttc ccaaaagccc
     8401 atgccgtaaa taagcaataa acccaagagg gtaaatacgg ctgtcccctt acccgactta
     8461 aaccaggcga gcgcagccag cactgcaatt gtgatataaa aaggtattcc aaacagtacg
     8521 tgctgaaaac cgtctatgaa tcctccgatc cccatgctga gagcatcaaa aaaggaagca
     8581 aaatgttctg tgagccaatt aatggcagtc tctatatatt gtccgatatt tatcataatt
     8641 ctattgcgtt ttgaatgatt tcattaattt cttctttatc ttttcccgtt acttcgatga
     8701 tcaatgagga aagtggcact acgccttcaa actcccgatt ctcatttacg acccagattg
     8761 gcgagttcgt ttttgtcatc aacggaagaa tatcttccag caccgtatca cccagcactg
     8821 aatgaacttc atgccttact acggactcga tggagcggat ttgctctttt cgtagtttca
     8881 gcaagtcatt caaccgcacc tctcctacta acagattatt ggaatcgact accggaagaa
     8941 cggtcagatt ccgttcgcgc atcttacgga tcagcacctc cgggccttct ttcttcaaac
     9001 gtgccactat gggtttatct accataacag aggaagctgt tataatcttg cttcgatcta
     9061 cattctccac aaatcgttct acataagcgt tggcaggttc ggtcaggatt tcttccgatg
     9121 taccgatttg tacaatttct ccatccttca tgatagcaat ccggtcaccc aatttaatcg
     9181 cttcactcag gtcgtgagta ataaagacaa tcgttttttt catcttcgac tgcaaagtca
     9241 gcagttcatc ctgcatctgc acacggatca aaggatcgag tgccgagaag gcctcatcca
     9301 tcaacaggac ttcgggatta ttggccaaag cccgcgccag cccgacacgc tgctgcatcc
     9361 cacccgacag ttcacttacc atctgattct cgtagccttt cagccccacc agttgcatgc
     9421 tttccatcgc tttctgctcc cgttctccct tttttactcc ctgtagttcg agcccgaaag
     9481 ctatattatg caagacagaa cggtgaggaa gcagaccgaa gttctgaaag accatagcca
     9541 gttctttccg gcgaatctgc aacagttcct tatccgacac tttggctatg tctgttccat
     9601 tgataatcac ttctccggaa gtagggcgta tcaaacggtt gatgcagcgg agtaaagtgg
     9661 actttccact accggacagc cccataatga cgaatatttc gccttcatta atggaaagat
     9721 tcgcatcttt caccgcaact gtacatccgg tcgctttcaa tatttcactt tttgttttac
     9781 cttctttcaa catcttcaaa gccttctgct tctcattgcc aaaaaccaga tagagatctt
     9841 taatttctat tttactcata caataaaatg gtttaggtta ttaaaataat atacacagca
     9901 agacaagaac aaacgataac aggaatcttt ctttatatcg tataaagttc tgatttaaat
     9961 acgggacaaa taacaatgaa tcccgaaata attaataaaa tgattattga cagactgagt
    10021 aattaaaaaa ggaatagaat ttgataagat aatcctttca acgaatagca aaaaatagca
    10081 tttttatgta taaaaacagc ctgttccagt atcttgctgg cacaaagata caaaaaacgg
    10141 attaaacata caaattatat tcaaaatccg gggcatacag agggctttat ttgtaatgat
    10201 atggaaagtt tccgggtaat attcccctat cactcagcaa aatagaacaa accggcagat
    10261 aaatataaaa caagtttgaa tatttcactt aaacaccgta tatttggcgt caataactaa
    10321 actagattta tatgttcaac agggctatta caattttcct ggggaaggat aattgtcatt
    10381 acacaacaaa agaaaaacaa acaggtactg ccacactaga cgacaaaagc caagtacagt
    10441 tccttagtaa aaagaacccc aaaatgccgt ttttctatag ccggcggaat ctctacatga
    10501 taggtttcct gctcgctttt atagtgactc tgctcgaatt tatacgagga cggcatcaaa
    10561 actttatggt cttctcggac gctactcaat tcttctggca aggcatcagc ccatacacaa
    10621 ctgaatttgt agaagctcac ggacgctact tcctttattc tccagttttc acggtattgt
    10681 tcgctccgtt tgcgtatctg cctgcatggc tgggaccttt cgcgtggaat ctattcaatt
    10741 attcgctgtt ctttatggcg atcttcacgc tgccccaaca attcacccag cagcagaaat
    10801 gccgtatgtt cctttttctg ttactgattt taggacaaag tttactttca tttcagtata
    10861 acataacggt agcctattta ttcttattcg cctatacgtt attggaaaaa gaccgtgaat
    10921 ttctggctgt tctgttaatc atgatttcgg gatgtaccaa agtatatgga attttcgaac
    10981 tggcattgtt gctgtgctat cctcacgtat ggcgtaactt tggctatgcc gttacaatgg
    11041 gcattgtatt gcttgcatta ccgttaataa aaatagctcc tgcagatttg ctcccctatt
    11101 atgaagaatg gtgccatagt cttgctgttc atcagtccgc cggagcttat gattcatttt
    11161 tctatgcccg ccccattgca gcatggacat tgccacactt ccgtgcactt cagataggaa
    11221 tgctcggctt gctgactctg ctctttttgg ggaatttccg caaatggtcg tcttttgcct
    11281 tccgtgccca ggctttgggc attctcatgg gctgggtagt attactgagt gactccgccg
    11341 agaagcatac ctatattatc gcattggcag gtttcatgct ctggtattgg agcagaccaa
    11401 cacgtaccgc aacagacaag attctatttt ggtgctgttt tgtgctgtta tgtatcgttc
    11461 ctatcgacat attcgtccct gtacccatca gagatttcat taccaggacc ttatggcttc
    11521 atgtatgggt tttctttatt gtatggatac ggatgatatg gcttaccttc cttgcatcct
    11581 tcattcatcc acgtgccaca aatgttcttt cagattaacg catccgttag ctttgaaaga
    11641 aacttcttct gccagcaaga gttgtttttg ttccacccaa ccgggcacca gccttccggt
    11701 ggaatttaca actctatggc agggaatgga taattcatcc ggcacttctt tcaatgcacg
    11761 tcccaccatc cgcgagcatt ggggtgcccc caacagcaaa gcaatacctc cataagtaga
    11821 tacttttccc acaggtatct gggatacgac ttcgtacact tccttccgaa aggattcgga
    11881 aaagctctct ttatctactt tataatcttt catatatccc tctttacgat atcaatgaaa
    11941 tcatcctttc cttttcagga aatctgtcgg gctctctcca aactgctctt tatagcactt
    12001 ggcgaaataa gaaggtgaac tgaaaccgac ttcataacca atctccgcta cggtcatgtc
    12061 cgaagaagca agcaaagaag ctgccttctt caaacgggcg atacggagca attcattcgg
    12121 agagtagtta gtcaatgatt taatcttgcg ataaagctgc acacggctta gtcccatgtc
    12181 tttgcccaag tcctccacat tcaaaccgga gtctcccatt ttctcttcaa tcaatgactt
    12241 gaatctttct acaaaatcct tgtccatatc gcagacatct tcttttgcca atgtctgccc
    12301 gtcaccaaag aactgtttca gacgacggtg agaatcgatc agattgcgga cacgtgccag
    12361 caacagctgt gaactgaacg gctttgaaat ataagaatcc gcaccaccgt catatccctg
    12421 aatacgctgt tcgtccagtg aacacgctgt cagcagaata accggaatat gacaggtctg
    12481 taactcactt ttcagccggc ggcaacattc aatgccatca atgcccggca tcatcacatc
    12541 agaaatgatc aggtccggaa catacttcat agccttacgg attccttcgg agccgtctgc
    12601 cgcttcaatc accgtatagt ctgtatgcaa caacgtatgg acatacgaac ggatatcctc
    12661 attatcatca ataatcagta cggacggttt ggaagagtca tatccttttt ccagttcttc
    12721 ctcttccgcc aatagaacat ctgttgtacg ggaatccgca gaaacaaggg tggtatccgg
    12781 ttcggcagca acagcctcac aagactgtac aggcagttca acggtaaaga ccgtgccctg
    12841 tttctcatcg ctctctacgg agatcatacc accgtgcatt tctacgaagg cttttaccaa
    12901 tgccagtccg attcccgaac cggtatggtg catatcgatc ttatagaaac ggtcgaatac
    12961 attgcgaata tgttcggcag aaatcataga accggtattt gccaccgtga aacgtatcca
    13021 tcgcttgtcc tctttactaa gggaagacag acggacggct attttcccgt tttccggtgt
    13081 aaacttaaag gcattggaca gaagattgaa ataaatacgt tccagcttct ccatgtctgc
    13141 cagtgtatga taatccgtat ccggcatact atcaaaagaa aaatggatat gcttcttacg
    13201 ggctgccgcc tgaaaagact cattccatcc ttcgaaagaa gaaaggacat ccaccgtaac
    13261 cggagtatat tccatcttgc cgttttcata tttacggaaa tccagaatct gattgaccag
    13321 acgcagaaga atgttcacat tccgctgaat cagcatgagc atccggtgct gatctccgct
    13381 cagtgtcttg tccgccaaca aatgttctac cgggtcggca accaatgtca acggagtacg
    13441 gaagtcgtga gaaatattgg tgaaaaagac cagcttggca tgggtagctt cttccagttg
    13501 atgagagagc tgtatcaatt ggtcacgctg ttcttccagt ttgtcacgct gctcttccaa
    13561 ttgctgtttc tgcttaaaaa gctctttatt caagcgattc ttagagcgga gtgatttata
    13621 aacgaccaat aataaaccgg ctaccaataa aaggataatc agactgccgt ataaaacgac
    13681 ctgttgtgta gctacctgag agaggtatcc accgatacgt ccgttgagcg tttcaatctt
    13741 tttgtcgagt tcggaaatgt gtgtggtctg caactgcatg acgtgtgcgt tggtacggtc
    13801 cacaacagcg gtattcatca ccgtttcttt gggatagggt ttcttctcca gaatgtccat
    13861 agccagttgc agtaccttat cgccattggt cggatagata aaggtggcat ccagcacact
    13921 gtccagtacc agttccagtc cgtttccctt acccggcaag gcatctatgc cgacaaaaat
    13981 catttccttc tcccgccctg ccatctttgc tgcctgatag gcacccggag cgatacggtc
    14041 attatgggca tacacagcat caatcttagg atgcctccga agcatactat ccatttctat
    14101 ctctgccgga ccacgttccc acgcagcatc cgctttatca atcagcttta tatccgggaa
    14161 tttactgatg gcagccataa atccctgatg ccgttccatt gcaggagtcg aaccgctcaa
    14221 tcctgtcagt tctactatat ttcccttccc tttcagactg gaggcaatat agtttcctac
    14281 cgaacgaccg atttcataat tatcggctcc gatataggca gtatatttat ccgaaagaat
    14341 cttccggtct acaagaataa cggggatgcc tttctgataa gcttcttcta caatcggagt
    14401 cataggagca gcttcgttag cggaaataat cagcagatcg actccttcgt ccataaaata
    14461 atggacatct tccgcctgct tactgttatc atcccctgcc gaacggattt ccaccgaaac
    14521 accattataa aacatcgctt cccgaagaat ctcatcattc atcttatgtc gccatgaatc
    14581 atcgctgcat tgagccaccc caatacgaaa acggggtgta tcctgccggc aagccgtcat
    14641 cccgattaaa ccaaacagca ccagcatcca cttcagatat ctcatcgtct tcatccatct
    14701 catcatttca tagttctttc tgtaatccaa ttaagaacaa aaataagaaa taatactgta
    14761 aagttctcta acttcagcta tttattattc taaaaagaag gaaagcagtc ctctttcaga
    14821 ccatcggaaa gtattaacaa aagtataaag cgtaaaacaa acacttaatc aatgttataa
    14881 aacatagcgt tttacttgga taatttgcag atttcacaga agtccgtatc tttgcactgt
    14941 gtttttcata gtattagatt taaggttaac aaaggttgga gcaaggcgtt gctccttttt
    15001 ttatgctctg acctttcatc taccggttag ttttcatccc attccttttc cagtttacca
    15061 tcaatagtgt agcgtttcca tcgtcctaca cggtgaccat tcttatattc cccacattca
    15121 cgaagctggt cattctttac ataacgagct tcgaacggtc cgttctgcct tccgttcaca
    15181 taggtagaag tttcccaata atcaaagcgg ttgctcacta tcagccgtcg ttccttgcca
    15241 tgcaatctgc cggcctgata ggtagcttca tatctcaatt caccattttc caaattatat
    15301 tcacggtata aaccgtcttt acgatcgttc ttcatataat attctttctg ccttacccca
    15361 cttccgttgg caaatgagac atggagtcca tcttcttttc catccagata ggtttcaatc
    15421 atcagcgtat ctccgctttc agcaaaagta gtccaacgac cattcttctt tccattctta
    15481 taactaccca gtatacgtgg cgagccaaac gtaaacacgg acgaatattc accgtcctga
    15541 aaaccttctt cattgaaata aacggtctca tacaaatcat atgtaccttt cagaaaagta
    15601 tactgtttgc ctacctgctt cccgtccttg taattatgct ctttccgcaa agtaccgtca
    15661 gattcgtacg acagttgctt cccgtgctct ttccccatcc ggaagtttct ttcactttcc
    15721 acttttccgg tagtaaagta acttttgctc gtaccgtcca gcttaccttc cttataggac
    15781 ttttcttctt tcagcttacc gtcaaacttg gagttaatct tgaagaggcc atccttccgc
    15841 ccttctttat aacttccttc cgttattaat atattgtcca catattcttt gtatccgcca
    15901 tcataaaaac catctttaaa agatgccagc acataggcgg aatgataacc atctatgatg
    15961 cgatgttcgc cattcaatgc tttttccgtt ttcagttcct gaaacaacag tctgccatcg
    16021 cctacattaa caacagatac ctgatcgatc ttatattcct tttgcgcaaa caaaggaaga
    16081 gcaagatata aaaacaaaaa tacgttccag ctttttgatc tgaggaagtt cgaaatgtgt
    16141 ttcataaagt agttttctct ttttgatcta ttatttaaaa acctgccgca aagataggca
    16201 atcggcttat aaaacaaggc aaggaagagg gggacaatta gaaaaaagaa catctgttat
    16261 tatcattcta ataattaaca gattaagtag taaatcaaaa cacagggaag ggggacattt
    16321 actgaaataa gaaacagaaa agaaggtgtg tcaaaagtaa ctaaattccc ctccttcctg
    16381 aaggaggaga atttagttgc ttttgacaca tttacatttg cagtattaaa tatcacaaca
    16441 aaatataagt gtatatttga aaagtagagt tgcag
//
