LOCUS       gnlProkkaBFLNKIEI_38   15019 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFLNKIEI_38.
ACCESSION   gnlProkkaBFLNKIEI_38
VERSION     gnlProkkaBFLNKIEI_38
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:51:33
            Original ID  :: gnl|Prokka|BFLNKIEI_38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15019
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15019
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4674:5019]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4675..5019
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15019
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15019
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2..1237
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.6; E-value:
                     7.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg38_1"
                     /transl_table=11
                     /translation="MAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGESGV
                     GKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFGEA
                     DGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAIAE
                     GRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKILL
                     AYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFESE
                     REILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAIIHA
                     VQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNISER
                     TLYRKIKEYELD"
     CDS             1224..1751
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MNWIKKIARPLILIVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1756..2550
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVVDEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLKEEEKAKAASSAETNETGRTDETTETNTVEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2557..2952
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPAAE"
     CDS             3243..4631
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 91.3; E-value: 8.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4675..5019
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_6"
                     /sec_met_domain="PF05402 (E-value: 6.4e-18, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.7e-10, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQHEAGYESRVSTYLSQLQ
                     KDGFIKWIID"
     CDS             5040..5165
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MDNEVEQLEYYPIRSLSIINFPLSIKKRLPTGGQHILSVRP"
     CDS             complement(5113..5394)
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFF"
     CDS             complement(5416..6480)
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             complement(6554..8065)
                     /locus_tag="ctg38_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVEADVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             8727..8951
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             9144..10688
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 56.1; E-value: 3.9e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_12"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVALIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             10730..11266
                     /locus_tag="ctg38_13"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             11300..11869
                     /locus_tag="ctg38_14"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMLDLEVPEDELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTSPLIDWYKNE
                     KKYQHINGLGTMDGIFADICEAVDKL"
     CDS             11882..13048
                     /locus_tag="ctg38_15"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKNRSFGKDGADKVIEVPCGTVVYNAET
                     GEYLCDVTDDGQEVILLKGGRGGQGNSHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSAISAAKPKIADYPFTTLEPNLGIVSYRDGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     ITKSDMLDQELMDEIEPTLPEGVPHIFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEELDYEYEEDADDDDDDLDYEYEEEDWEEK"
     CDS             13072..13857
                     /locus_tag="ctg38_16"
                     /transl_table=11
                     /translation="MLGYESLSSYSNISHFVTTRQGGCSEGNYASFNCTPYSGDEAEKV
                     RRNQTLLMEGMSQTPEELVIPVQTHEANCLLIGDAYLSASSQQRQEMLHGVDALITREL
                     GYCLCISTADCVPVLIYDKKHSAIAAIHAGWRGTVAYIVRDTLLRMEKEFGTSGEDVIA
                     CIGPSISLASFEVGEEVYEAFQKNGFDMPRISIRKEETGKHHIDLWEANRMQILAFGVP
                     SGQVELARICTYIHHDEFFSARRLGIKSGRILSGIMIHK"
     CDS             13897..14562
                     /locus_tag="ctg38_17"
                     /transl_table=11
                     /translation="MFEIKVSQEIKNACPVFAGAAVYAAVKNTAYCDGLWKEINTFTED
                     LTTTTQMADIKLQPVIAATREAYKRCGKDPGRYRPSAEALRRRLMRGIPLYQIDTLVDL
                     INLVSLRTGHSIGGFDADKIQGKHLELGIGKAEEPFEGIGRGILNIEGLPVYRDSFGGI
                     GTPTSDHERTKMDVGTTHILAIVNGYNGKEGLKEAAEMIQSLLRDYAGSDGGELIYFE"
ORIGIN
        1 caaagcggag atacaacaag tgaaacagcg tttcggtatt attggcaata ccgaggcttt
       61 atcacgtgcc atagatgttg ccattcaggt agcgcctacc gatttgtctg tgctgattac
      121 cggagaaagt ggtgtcggaa aagaaagttt tccacagatc attcatcaat atagccggag
      181 aaagcacgga cagtatattg ctgtcaactg cggtgccata ccggaaggta cgatcgattc
      241 cgaactgttc ggacacgaga aaggagcatt taccggtgct attggtgagc ggaaaggata
      301 ttttggagaa gctgacggtg gaaccatctt ccttgatgaa gtgggagagt tgccgttgcc
      361 tacacaggcg cgtctgcttc gtgtacttga aagcggtgaa tttatcaagg taggttcatc
      421 caaagttcaa aagacggatg tgcgtattgt ggcagctacc aacgtgaacc tgacacaagc
      481 cattgccgaa ggacgttttc gggaagattt gtattatcgg ttgaacacgg tgcctattca
      541 gataccacct ttgcgtgagc gcggagatga tgtgctgttg ttgttccgta agtttgccgc
      601 agactttgcc gaaaagtacc ggatgccggc tatccagctg acggaagatg ccaagaagat
      661 attgcttgct tatccgtggc cgggaaacgt ccggcagttg aagaatatca cagagcagat
      721 ttcgattata gaaacaaacc gtgagataac ggctgcgatt ctgcagacct atcttccggc
      781 acagaatacc caacgccttc cggcactgtt cggcacacgc gagagcaaga gctttgagag
      841 cgaacgcgaa atactatatt ctgtcttgtt cgatatgcgc caggaagtgg cggaactgaa
      901 gaagatggtg cacaatatga tggccgaacg tgcgggacaa gtcggacaga tgggacaggt
      961 agtggctact ccggtagtga cgacgacgca ccaaccatct gtgccggcca ttatccatgc
     1021 tgtgcagcaa ccgtctgttt gtcccaaaga agacgatgac gatattcagg acacggaaga
     1081 atatgtggaa gaaacccttt cgctcgatga agtggaaaaa gaaatgatac gtaaagcgct
     1141 tgagaggcat catggtaagc ggaaaagtgc ggcaaaggat ctgaatatct ccgagcgtac
     1201 cctttacaga aaaataaaag aatatgaatt ggattaagaa aatagcacga ccgctgatac
     1261 tgattgtttt accggcagtc atcatcgcct gtagtgtgtc ctataagttt aatggctcct
     1321 ctatcaatta cgataaggtg aagaccattt cgattgctga tttcccgatt aagtcggagt
     1381 atgtgtatgc tccgctggct accaagttca atgaagacct gaaagatatc ttcatcagac
     1441 agacccgtct gcaactgctg aaaccgaacc agaatgcgga tctgcagatt gacggtgaaa
     1501 ttacgggcta caaccagtat aaccaggcag tgtctgccga tggttactct tcggaaacga
     1561 agctgaccat cacggtcaat gtacgctttg tcaacaacac aaatcacgcc gaagacttcg
     1621 aacaacaatt ctcagctttc cgtacctatg attccagcca gctgctgacg gccgtacagg
     1681 atggattaat agcggaaatg agtaaagaga taaccgacca aatatttaat gcaactgtag
     1741 caaactggta atttaatgac ttctgttaac ttgcaacaat ggattcagca tcccgagacg
     1801 ctgaataggg atactttgta cgaactgcgc aaccagctcg cgaggtatcc gtattttcag
     1861 tcgctccggt tgttgtatct caagaacctg tatattctcc acgacattaa tttcggtgcg
     1921 gaactgcgga aagccgttct gtatattgcc gaccgacgga aactgtttca tctgatcgaa
     1981 ggcgaacgct tcgctgtcga atcccagaag aaaggactgc ctctctctga agtattgaaa
     2041 gatgagccta ccgtcgaccg gacactggct ctgatcgatg ctttcctttc gacggctccc
     2101 gaagaagtaa ccagtcagac aagctttgat tactccatgg actatacggc ataccttctc
     2161 gaagagacac ctgtcgtcga tgagccggca gaggcaatgc ccaagttgaa aggacacgag
     2221 ctgattgaca actttatcga aaaaagcgag actgatccag tcgtatacct gaaacctttg
     2281 aaggaagaag agaaagcaaa ggcagcttct tccgctgaaa caaacgaaac gggcagaaca
     2341 gacgaaacaa ctgaaaccaa caccgtagaa gaggaagatg acagctgttt cacagaaact
     2401 ttggccaaaa tctacgtaaa acagcaacga tattcgaaag ctcttgaaat aattaaaaaa
     2461 ttaagcttga aatatccaaa aaaaaatgct tactttgcag accaaatcag atttttggag
     2521 aaattgatta ttaacgctaa ttcaaaataa ctaaaaatgt acttattatt cattatctta
     2581 atggtgattg cagccttgct gatgtgcttc atcgtgctga ttcagaattc aaaaggaggc
     2641 ggacttgctt ctggtttttc ttcatcaaac gctatcatgg gcgtgcgcaa gactacagat
     2701 tttctggaaa aagcaacttg gggtctggct atcttcatgg ttgtgatgag cgttgctact
     2761 gcttacgttg ttccttcttc ttctgcagct aaagatgtat tgttggaaca agcacagaaa
     2821 gaacaacaaa ccaatccgta taatatgcct accggtactg ctgctcctca gacagacgct
     2881 actgctcctg cagagtctgc accagcaaca gaagctccgg ctactgaaac tcctgctcct
     2941 gcagcagaat aattcagtga caggatattc ggtttaaact tattgagtga acgggctttt
     3001 tgacccgttc tcttcattat aggcgcgaat tacgcgaatt acaagagatt ctaatagaat
     3061 tgtgtaatac gtgtggttcg cgcctatctt tattattggg tccggtctgc tcttcttcat
     3121 acaggaatat ccggtcagat gtcctttttc ttataaaatg ttctcctttt ttagtaaaac
     3181 aaatgataat tagttaactt tgttgcccgt tacgagatta ttaactcctt ttaaatatta
     3241 caatgacaga acaattgaaa caaaagctga atgactccgc agtgctgcgt tggagtgttc
     3301 tagcattagt cgcttttacc atgttgtgcg gctacttcct cacagacgtt atgtctcctc
     3361 tgaaacccat gcttgaaaaa gaacttctct gggacagttt agattacggt tttttcacca
     3421 gtgcttatgg ctggtttaat gtattcctgc tgatgctcat ctttggtggt atcattctgg
     3481 ataagatggg agtacgcttc accggaatgg gtgcctgttt attgatggtg tttggttgtg
     3541 gattgaaata ttatgctatt actactactt tcccggaagg tgcgatgctt ttcggattca
     3601 agatgcaagt cacattggct gcattgggct atgctatttt cggtgtagga gtcgaaattg
     3661 cgggtatcac cgtttcgaag attatcgtga agtggtttaa aggcaaagag atggctctcg
     3721 ctatgggact ggaaatggcg accgcgcgta ttggaacaac tttggccatg gtgcttaccg
     3781 ttcctttggc agacttcttc gggtctacgg atgagagcgg cgtattccat accaatattc
     3841 ccgctccgat tctgttctgt ctcgtcatgc tgtgcgtagg taccatcgca ttcttcatct
     3901 atactttcta tgataagaaa ctggatgctt cactggatgc ggaaggactg gaaccggaag
     3961 aacctttccg catgaaagac atcgtatata tcattaccaa caaaggattc tggctgatcg
     4021 cattactgtg cgtattgttc tattcggctg tattcccctt catcaagtat gcggctgatt
     4081 tgatggtaca gaagtacaat gtagatccga aacttgcggg aacgattccc ggattgctgc
     4141 cgattggcgc gatcatcctg acaccgttgt tcgggtcatt gtatgaccgt atcggtaagg
     4201 gagccacgct gatggtgatc gggtcggtga tgctgatttt cgtacacact atgttcgctc
     4261 ttcctattct gaatatctgg tggtttgcaa cggtgatcat gattattctg ggatttgctt
     4321 tctcattggt tccttcggca atgtggcctt cggttccgaa gattattccg gagaaacagt
     4381 tgggaacggc ttatgcgttg atcttttggg tacagaactg gggattgatg ggcgtgcctt
     4441 tgctgattgg atgggtgttg aattcttatt gcaaaggtcc ggttgtagat ggtgcacaga
     4501 cttatgatta taccttgccg atggctattt ttgctatgtt cggtgtactt gccctgattg
     4561 ttgccttgat gctgaaagca gaaaacaaga agaaaggcta cggactggaa gaagcaaata
     4621 ttcagaaata atccagtata tattctatct gaaaagatat aaaagagaaa agatatggct
     4681 acgaaagaga aaataaacct cctggaggtg atcccttgtc gtaacgaaca tattaaagct
     4741 gaacaggaag gggagactat tgtgctctcc ttccctcgtt ttaaacgttc gtggatgagt
     4801 cgttatttat tgccgaaagg aatgtccaaa gatattcatg tgcgtctgga agaacacggt
     4861 acggccgtat ggaacctgat agacggccag cggacggttc gtgagattat agaaaaactc
     4921 gcagaccact ttcagcatga agcaggctac gagtctcgtg tatctaccta tctttcccaa
     4981 ttacagaaag acggatttat taaatggata attgattaat ggataattga taatggaaaa
     5041 tggataatga ggttgagcag ctggaatatt atcccatacg ttcattatcc attatcaatt
     5101 ttccattatc cattaaaaaa agattgccca caggaggaca gcacatccta tcagtacgcc
     5161 cataatgatg agcgttcccc atacgaaata gctgttatct ttttcttttt tcttttccga
     5221 atccttgatg atgcgttcca tctcttccgg agtcgtatcc ggcagaagat aagggtcgtt
     5281 gtttcttcta agtcgcccta acttgtcatt tctccgttca cggcgtaagc gggaggcttc
     5341 tttgccgtct ttcagccgac gtatcatgtc gagcatatgt ccttcgccac ccatcgtttt
     5401 gtttttttag aggttttatt tgctttcttc tctatctact ttcagtagtc caccggtcac
     5461 cggatcaaag taaactttga tggtcgagtt cttgttgaat aataccggag caaggtattc
     5521 tatgataccg aactgagtaa caggtatttc tccttcatac aatttctttt tgccgtccgt
     5581 cagcgtcacc attgcctgtc ccggtacgtt ataagcaatg ccttccatct ctttcttctt
     5641 ttttccgtcc tcttgcggaa tcttcaccgt tttcaggtct ttcagactga tgtagaatgg
     5701 agtgcctgcc aaatcgttgt tggcaactat acccagcttc tttgaaaagc ggaaagctac
     5761 ctcattgtcg aattccttat ccggagtgag gcggacagta aatgtctttt cttctttatt
     5821 gcggactccc gaaaacatct cggtcatggc ttcttcctga agattcaggt tgtcgagcat
     5881 gattttgagc tgtgcgccgt ccgaaggcat attatctgct tgtccgcgca ataatgcgtt
     5941 tttactttcg cggatattat agatttcctt tgctaccagt tcggccatct tggcggttga
     6001 acttgccatc agaatttctt ctgtgagaaa gtcgcgggga ttggcttttc gttggggagc
     6061 aacggcattg tttgctgcat tctttgcatt gttgctgctg taggggacgt tgattgattt
     6121 gataagaccc tcttcagtca gttccataag aggagctacg gttttgtctt tcagtttgac
     6181 gaaataagta gcttcgctgt ttggtacacc tacaggtttc actttgacac tgttcagttc
     6241 ccagtattct tcgggttcgg cagagacgtt ggtcagtctc aggtagcggt cggcgtattt
     6301 gctgaattca cccggcttat agttgacttt gtttgctttt atttctattt ctatctgggt
     6361 tttggggagg gcgtacacta ctccgtagtc ttttcctcgc gtcactcctg tcagcacttc
     6421 ggtctgcgca taggcggaag ttgccattag tagtcctgtt gctatgatta actttttcat
     6481 attcggttct ttttagctga ttttgaaaaa caaagttaat gaagttattg aataaaccgt
     6541 aagttcttaa cttttattcg cttacaagtc gccatgccgt cggcagacag gtcacgatat
     6601 cacttgcgat taatccgatc atgccctgtt ttttctgggc gatgtctccg gccaatccgt
     6661 gaatgtaagt accgatcttt gcggcgtctt cggcgggata gccttgcgca aggagtgcaa
     6721 ggattactcc tgtcagtaca tctccgctgc ctcctgttgc cataccggga ttaccggtct
     6781 ggttgaagta acatttgcct tcgggggtga taatggcgga ataagctccc ttcagaatga
     6841 tatgtacttt ggcagtgtgc gccagttcgc aggctttcat cagtcgttcg tatgagtcct
     6901 gacatttgcc gaccaggcgt tccagctctt tcgggtgagg ggtgaggatg gaacctttcg
     6961 gcagatgggt gagcgtatgc cggtgattgg ccagaatatt gagtgcgtcg gcatccagta
     7021 ccgtcggagt ctgacaatgt tccagttgtt ctatcagggc ggcttccgtt tcctcgttgc
     7081 gaccgagtcc cggaccgatg ccgacagctt ggtaatcgtc cgtatcggta ggtacggcaa
     7141 agcatgtttc gctgacatct gcttctacca tggcttcggg ggcggacgtt tgcagaatat
     7201 cgttgttgca taacggcgcg tgtacggtca gcagacctac tcccgagcgc agacaggcac
     7261 gcgcggccag taccgatgca cctgccattc cttttgagcc ggctatcagc agggcatgtc
     7321 cgaagtttcc tttatgggcg aattgttggc gtggtttgat cagtgaacgg atttcttcga
     7381 tttccagcat ttcgtagttt gtttcagtct cttcgattcc ttcttcgctc agctggatgt
     7441 ccaataactc ccattcgcca acaaattctg tattttcggc aaagaggaag gccagtttag
     7501 gaagttgcag gctgaaagtg acgtccgcac ggataatatt gctttttaca ttgaatgtat
     7561 tttcttctcc catcagtccg gaagggatgt cgatggagac taccatggcg ggagaggcat
     7621 tgatatattt cacaacggca gcgaatcctc cgctcaatgg tttgttgagt ccggaaccga
     7681 ataatccgtc gatcacgaga tgttccggtg tcagtgtggg aggtacgaac tgggtgctga
     7741 tttcatggaa agttacttct tccatcatct ctaccagttc tttgttggtc tggcagtcgg
     7801 gcgaaagttc gcctttcgtg ttgaagagat atacttcgat cttgtatcct ttttccgcca
     7861 tcatgcgggc gatggcgagg gcgtctccgc cattattgcc cggtccggca aagatggtga
     7921 caggtgtttc cggattccat ctgttggtga tggctttagt cagcgcctgt gcggcacgct
     7981 ccattaaatc tatggatgca atcggttcat gttcaatggt ataggcatct aacttcttaa
     8041 tgctgctgct tggaaatatt ttcattgcga tattctttta gttttcgacg cacaaactta
     8101 cacaaaaact ctgaattaat cctttattcc ggttggtttt cggctttaga taaagtggca
     8161 aattgaaaaa tgcaggggaa atcagaagtt atcttggggt ggctttgtcc tgtctgtctg
     8221 tgattcctca gttggggggc ggatatttct ctgcaaaggt acgggcattc ttcagataag
     8281 atgcggagac ttttcggcta agatgcaggc attcttctct taaagtgcct ttttctttag
     8341 ttgctcacgg ccgtgacaag acttcgccac gaccgtgagc aatgctaatc acggtcgtga
     8401 acaatgcttg tcacgaccgt ggtcagttaa tgatatcggt gctttgatgt aactattcta
     8461 ctgctttctc cttaatcttc cgatactttg agagatagtt acgccttctc cggcctgcta
     8521 tagaactgct tcctttatga gtgtcttcgg cgtttggaat aaagctgtca gtagatatgg
     8581 tacaatataa acagctaatg ccttgattat ttgctttttt cgaaaaaaat gatatctttg
     8641 tagtgcagta atgtgcttta cgttattctc ctgtgctcac aatgtttaga ttataaatat
     8701 aaattgttta atcttctaaa gtttgcatga tggaaaagaa aagaattggc tcaaatgccg
     8761 ggaaagtatg gcgcatctta aatgaaaagg gcgaacagtc tatgttcacc ttgtgccatg
     8821 agttaggttt gacgttcgag gatgtagcga ttgctatcgg ctggttggca agggaaaata
     8881 aaatcctgct tagaaaaaaa gaaggaatgc tctatgccag tattgagaat gttgaattta
     8941 cttttggata aatggcgact gacccacatt taaggggaat atccacttga ttatttacac
     9001 tgttgaaaac ataataaggt gggtaactga gacttcttgc acgccatcct gtatttttct
     9061 attccataag aatcttcttt tttgaggcat ttaatctact ttttagtacc tttgcacccc
     9121 ataaactact aaacacataa ttcatgagtt cattgaaagg gcacccgaaa ggcctttacc
     9181 taattttcgc aacgagcacg gcagaacgtt tcagttacta cggtatgcgt gccatcttta
     9241 tcctctttct gacgcaggca ttgctttttg ataaagaagc ggcagcctct atctacggta
     9301 gctacaccgg actggtctat ctgactccgt tgatcggcgg atacattgcc gataaatatt
     9361 ggggcatccg tcgttcggta ttttggggag cggtgatgat ggcagtcggt cagttcctga
     9421 tgtttatgag tgcctcttca ctgaacaata cagaccttgc ccactggctg atgtatggcg
     9481 gactcggatt catgatttta ggtaacggtt gctttaagcc taccgtttct tcgctcgtcg
     9541 ggcaattata tgaacccggg gacaaacggt tggatgctgc atacaccatt ttctatatgg
     9601 gtgttaatgt aggttctttc gctgctcctt tgatttgcgg tttcttggga gacacaggga
     9661 atccgcagga ctttaaatgg ggattcctcg catccggaat catgactctg ttcactgttg
     9721 tcctctttga aactcagaag aataaatacc ttttctctcc ttccggtgaa ccaattggta
     9781 tcgtccccga cgccagacgt gaaaaaaagg aggataaagc cgaacatatt tcacatccga
     9841 agatggacaa acgtaccaaa gtacgtaata tcatcatcat tactgccctt acagttgcct
     9901 taatagcttt ttttagctat gcctttagcg atgactggat tagtgtgggt atctttacgg
     9961 cttgtattgt ctttccagta ctcattctgc tggatggttc attgaccaaa gtagaacgta
    10021 gccgtatttt cgtaatctat atcgtagctt tcttcgtcat tttcttctgg gcagcttacg
    10081 agcaggcagg agcttctctg acattattcg cttccgaaca gactgaccgc agcattttcg
    10141 gctgggagat gccggcttcg tggttccagt cattcaatcc gctttttgta gtgatccttg
    10201 cctatattat gcccggtata tggggctttc tgaataagcg aaacatggaa ccggcttccc
    10261 ctaccaaaca ggcaatcggt ctgttgctgc tttctcttgg ttatctcttc atctgttttg
    10321 gagtgaaaga tgctattcca ggagtaaagg tgagcatgat ctggctgaca ggactttatt
    10381 ttattcatac aatgggagaa atcgctctgt cacctatcgg gctttctatg gttaataagt
    10441 tgagtccgtt acgtttcgcc tccttgatga tggggatctg gtatctttct accgccaccg
    10501 caaataaatt tgcaggtatg ctgagtggcc tctatcccga agacggaaaa gtgaaatcaa
    10561 tccttggtta tcagatcgct accatgtatg acttcttcat gctgttcgtc attatgtccg
    10621 gtgttgcctc actgattctg ttccttctct cgaagaaatt acagaagatg atgcacgggg
    10681 tagaataaaa aattgtattt ttgcgacaac ttttttaaaa tgaccggtta tggataccat
    10741 acagataaaa gacaagcaat ttactgtttc cattaaggaa caggatattc aaaaagaagt
    10801 gattcgcgta gcgaacgaaa tcaatcgtga tttggcaggt aagaatccgc tcttcctcag
    10861 tgtgttgaac ggctcgttca tgtttaccgc cgacttgctg aagcatatta cgattccgtg
    10921 cgaaatttca ttcgtgaagt tggcatctta tcagggggtg acttccaccg gagtaattaa
    10981 agaagtgatc gggctgaatg aagacattgc cggacgtacg gtagtgatcg tagaagatat
    11041 tgtagatacc ggactgacga tgcagcgtct gctggataca ctgggcacac gcaaccccga
    11101 agcgattcat atcgcctctt tgctggtgaa accggaaaag ctgaaggtca atctgaacat
    11161 agaatacgta gcgatggaaa taccgaatga ttttatcgtt ggctacggat tggattatga
    11221 tggtttcgga cgcaattatc ccgatattta tactgtagta gattaaattc aaatacaaat
    11281 taatttttag gttaaaaaga tgttgaacat tgtaattttc ggtgctccgg gttcaggaaa
    11341 aggaacgcag agcgaacgta ttgtagaaaa gtatggaatc aaccacatct cgacaggaga
    11401 tgtattgcgt gcagaaatca agaacggcac ggaactgggc aaaactgcta aaggttacat
    11461 cgaccaggga cagttgattc cggatgaatt gatgattgat attctggcaa gcgtattcga
    11521 tagcttcaaa gacagcaaag gtgtaatttt cgacggtttc ccaagaacaa ttgcacaggc
    11581 ggaagcatta aagaagatgt tggcggaaag aggacaggat gtttctgtaa tgttggatct
    11641 cgaagttccg gaagatgaac tgatggtacg tctgatcaaa cgtggcaaag actccggtcg
    11701 tgccgacgac aacgaagaaa caatcaaaaa acgtctgcat gtatatcatt cacagacatc
    11761 tccgctgatc gactggtaca agaacgaaaa gaaataccag catatcaacg gtctgggtac
    11821 tatggatggt atcttcgctg atatctgcga agcagtagac aaattgtaat aaataaaaaa
    11881 tatggctgaa tcgaattttg ttgattacgt aaagatatac tgtcgctcag gtaagggcgg
    11941 aagaggctct acgcacatga ggcgcgagaa atattgtcct aacggaggtc ccgatggggg
    12001 cgatggtgga agaggaggcc atattatctt gcgcggtaac cgtaattact ggacattgct
    12061 tcacttgaag tatgaccgtc atgcgatggc aggtcatggc gaatcgggca gcaagaaccg
    12121 tagtttcgga aaagacggtg cggataaagt gatcgaagta ccctgcggaa cggtagtgta
    12181 taacgccgaa accggagaat acctttgcga tgtgacggac gacggacagg aagtgatctt
    12241 gctgaaaggc ggtcgtggcg gtcagggcaa cagtcatttc aagacggcta cccgtcaggc
    12301 tccgcgcttt gcgcagccgg gcgaaccgat gcaggaaatg acggtgatca tggagctgaa
    12361 actgttggca gatgtaggac tggtaggttt cccgaatgcg ggaaagtcta cgttgctttc
    12421 tgccatttcg gctgcgaaac cgaagattgc cgattacccg tttacgacac tcgaaccgaa
    12481 tctgggaatt gtttcctatc gcgatggaaa gtcattcgtg atggcggaca taccgggcat
    12541 catcgaggga gccagtcagg gaaaaggatt gggactgcgg tttctgcgtc atatcgagcg
    12601 taactcgttg ctgttgttca tggttccggc agatagcgat gatatccgca aggagtatga
    12661 agtattgctg aatgagctgc gtacgttcaa tcccgaaatg ctggacaaac aacgtgtgct
    12721 ggctatcacg aagagcgata tgctcgatca ggagctgatg gacgagattg aaccgacatt
    12781 gcccgagggt gttccgcata tattcatttc ttctgtttcc ggtttgggaa tctcagtgtt
    12841 gaaagacatt ctgtgggagg aactgaacaa ggaaagtaat aagatagaag acattgttca
    12901 ccgtccgaaa gacgtgaccc gtctgcaaca ggaactcaag gacatgggcg aggatgaaga
    12961 actcgactat gaatatgagg aagacgctga cgacgacgat gatgatctcg actacgaata
    13021 cgaagaagag gattgggaag aaaaatgatt tcaatcacaa gagataaaag aatgttgggg
    13081 tatgagtcgt taagctcata ctccaacatt tctcattttg taactacccg gcagggaggg
    13141 tgcagcgaag gaaattatgc gtcattcaac tgtacgccct acagtggaga cgaggcggaa
    13201 aaggtccggc ggaatcaaac gcttctgatg gaaggaatgt cgcagacacc cgaagaactg
    13261 gtgattcctg tgcagactca tgaggcgaat tgcctgctga tcggggatgc ttatttatcg
    13321 gcttcgtctc aacaacgaca ggagatgctg cacggagtgg atgctttgat tacccgcgag
    13381 ttgggatatt gcctttgcat ttctactgca gattgtgttc ctgtgttgat atatgataag
    13441 aaacatagtg ccatagctgc cattcatgcc ggatggagag ggacggtagc atacatcgtg
    13501 cgtgatactt tgttgcggat ggagaaggag tttggcacaa gtggagaaga tgtgatagcc
    13561 tgtatcggtc cgagtatctc attggcttct tttgaagtgg gtgaggaagt gtacgaagca
    13621 tttcagaaga atggttttga tatgcctcgt atttctatca ggaaagagga aaccggaaaa
    13681 catcatatcg acttgtggga agcgaaccgg atgcaaatcc ttgctttcgg tgtgccgtcc
    13741 ggccaagtgg agcttgcccg gatatgtacg tatattcatc acgacgagtt tttctcggca
    13801 aggcgtttgg gcattaagtc cggacggatt ctgtcgggga tcatgattca taaataatag
    13861 acttgaacgt aagttgatat aaacttgaat agaagtatgt ttgaaataaa agtatctcag
    13921 gaaataaaga acgcctgccc tgtttttgcc ggagcagccg tatatgcagc agtgaagaat
    13981 actgcttact gcgatggact ttggaaagaa ataaatactt tcacagaaga cttgactacc
    14041 accacccaaa tggcagacat taagttgcaa cctgtgattg ctgctacccg tgaggcttat
    14101 aagcgttgcg gaaaagatcc ggggcgttat cgtccgtcgg cagaagcgct gcgccgtcgc
    14161 ctgatgcgtg gcatcccttt gtatcagatt gatactttgg ttgaccttat caatctggtt
    14221 tctctccgta ccggacattc tatcggtggc ttcgatgcgg ataagataca gggtaaacat
    14281 cttgaacttg gcattggcaa agcggaagaa cctttcgaag gtatcggtcg gggcattttg
    14341 aacattgaag gattgccggt gtacagagat tcttttggag gaatcgggac accgacaagc
    14401 gaccacgaac gtacgaagat ggatgtcggg actactcata ttctcgcgat agtcaacggg
    14461 tataacggaa aagagggatt aaaggaagct gctgaaatga ttcaatcctt actgagggat
    14521 tatgccggat cggatggcgg cgagcttatc tattttgaat aataaaggaa tacatgaaga
    14581 acatacttat tttattgaca gtcctgcttt taccaactct tgcttatgcg caaagtaaat
    14641 cctctttttc ttctatggag gtgaatcatg tacgggttgc tactcccgga ctttttgcga
    14701 aaagcaatca tatatatctg catttggatt ctttgcaaga gcatgaatat gcttttccct
    14761 taccgggagc caaagttatt tccgcttacg gaactcgcgg aggacattcg ggagcagata
    14821 taaagacgtg tgccaaagat acgattcgtg ctgcttttga tggagtcgta cgtatgtcga
    14881 agccatatta tgcttacgga aatttggttg tagtccgtca tgcgaacggg ctggaaacga
    14941 tttacagtca taacttcaag aatttggtac agagcggaga tacggtgaaa gccggacaac
    15001 ctatcggact gaccggacg
//
