LOCUS       c00032_gnlPro..        16486 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFLNKIEI_32.
ACCESSION   c00032_gnlPro..
VERSION     c00032_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 06:04:47
            Original ID  :: gnl|Prokka|BFLNKIEI_32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16486
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16486
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3116:6674](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3117..6674
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16486
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16486
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(544..1698)
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1878..3083
                     /locus_tag="ctg32_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3117..6674
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6799..6987
                     /locus_tag="ctg32_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6998..7858)
                     /locus_tag="ctg32_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7886..8716)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg32_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8713..9939)
                     /locus_tag="ctg32_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10412..11698
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11661..11993)
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12021..14774)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15107..16333)
                     /locus_tag="ctg32_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 gtcaacacat agcagctatt agagataaac aagtcaacca ttattaggga agtacagttt
       61 ccattgcttg aaaccagagt ttcatcggtg tgaaactgta gtttcatcgg tgagaaacta
      121 gagtttcata cgcttgaaac tttagttcca aacgctcgaa actatctgaa actactgttg
      181 atttgattga cttaaccgca tgttccaatc acattgaacg catcagctac ttcaatagta
      241 ctgctctctc tgaaaacatt aaatcatata tcagtcaata atacataaat tatcagtcat
      301 taatacctga tttctcaatt attaatatct gagaaatcaa acgttaacag ttgagatatc
      361 agatattaac atcctgtaaa tcaaagaata acacagtaaa aacagtattt atcaggacga
      421 tgcagagtga gagcaagtcc ttgctctcac tctgctacca ctggatctct aacagctaaa
      481 acatcgatga ataaagggat acagacgaac tgttagagca tgagagcaaa agcactatct
      541 ttttcactgg gggagagtaa gcaaaagaaa cgcacgatac cggctttgag gcgtcaccgg
      601 tactaacggc aaatatccgg cacacacccg attattctct acggacaaag ggaacgaagc
      661 cgacatctgc cgatgttcct ccaaagcctg accggctaaa ggataataat caatccgaaa
      721 aactccttcc gcatccgcag ccaaataacg atccgtcaag agccatgcca ccacccccat
      781 attcattcgc agattaattt cgacacaagg atgaatccgg taaacaggcg cttcatccgg
      841 aaaatgacaa atcatcatat ccactcccaa gtatccatga taaaagccac cgaacaaagc
      901 tgacaattct tcttccaaac gagtccgcag cctgataaat tcttcttgtg gcacataagc
      961 cgatagtttc tgcagaatct tctcgtcaga cagcaagtca ttccctgcat acatcccact
     1021 cccacccgtg tggaagaccg aatatccggc aaaaacaacc cttcctctcc cgtcagcata
     1081 aaactccata gcgaaatctt ccaccttatt atatataggt tcgcctacca ccccaccctg
     1141 agaagcagcg acacgggcac accaaccgga aataaaagta gtaaatatgc ctttacacca
     1201 attcaatcct ttcccgcttc cggaaagcgg agcttttaac aagcacgctt cccgcccttc
     1261 gacgaacgca ctgcactccg ccaaagtact caaataaaaa gattctccac agaagtattc
     1321 attcaaccgc aacccaggca acaactttac cgcctgcaga cgatgcgaat gctctctcag
     1381 aatattcata taatccgcag aaggcagctc cgtctgacct gcccccaatg tcatcaaacg
     1441 cttccgcaaa gcagggtccc aaccccacgg agagaacttc cagtctttac cgtcagccac
     1501 ttccggttcc gtcaacaagg ccacatccat gcccaaaagt tcactctttg ttttcaggaa
     1561 gtccgcatta taagcagacg gtgcaagcac cgcacttccc gcttcggcat accacatagg
     1621 aagcaacgcc aggtcactcg ccatctgtcg ggcggaagcc ggcgccatat agttcgtctc
     1681 accgcttgcc aacgccatat catgctccgg attgaatata taaacaggtc ttttcgtcat
     1741 gtcaaagatg gattcaacac attattctgc aaatatatac aggaaataat caggaactta
     1801 cacaataaag agaaacttat aaattaaagc acatttttgc tatctctact ttgcaaatcc
     1861 taaaaaaagc actatatttg ccagccgaaa aacaaagaaa cgaaatggaa tcattctatc
     1921 gcacacacgc ctacctcgtt gagcacacca atgcccccgt tcgccgcgat cttatggacg
     1981 agatcgactg gagtgaccgt ctgattggta tcaaagggac acgtggcgta ggaaaaacca
     2041 ccttcctcct gcagtacgcc aaagagaaat tcggcaccga ccgttcctgt ctgttcatca
     2101 atatgaacaa cttttatttc tccggtcaca gccttgttga cttcgccaac gagtttcaga
     2161 aacgtggcgg aaaagtactg ctgatcgacc aggtgttcaa acatcccgaa tggagcaaag
     2221 agctacgaat gtgctatgac cgtttcccca gcctgaagat tgtcttcacc ggttcttccg
     2281 tcatgcgact caaagaggaa aacctcgaat tgcgtgacat tgcgaaaagt tataacctgc
     2341 gcggattctc tttccgtgaa tttctgaacc tgcagacagg aatgaaattc cgggcataca
     2401 gcctcgaaga aatcctcagt acacatgaac agatagccaa aggagtactt tccaaagtac
     2461 gaccgctgga ttattttcag gattacctgc atcatggttt ctaccctttc ttccttgaaa
     2521 aacgtaattt ctcggagaat ctgctgaaaa caatgaacat gatggtagaa gtggatatct
     2581 tgctgatcaa acaaattgag ctgaaatatc tttcaaagat aaaaaaatta ctatatttgt
     2641 tggctgtgga cggaccgaaa gctccgaacg tgagccaact ggcaagtgac gtacagacat
     2701 cccgcgctac ggtaatgaac tatatcaagt atctggcaga cgcgcgtctg attaatctgg
     2761 tttacccgaa aggagaagaa ttcccaaaga aaccgtcaaa gattatgatg cacaactcta
     2821 acctgatgta ctccatttat ccggtgaaag tggaagaaca ggatgtactc gacacgttct
     2881 tcgttaacac tttatggaaa gaccataagg tacataaagg agataaaaac gtctctttca
     2941 tggtagacga agtgatgccg ttcaaaattt gtgcggaagg tacaaaaata aagaataacc
     3001 cggacgtgac gtatgcgttg caaaaggccg agataggccg cggcaaccaa atacctcttt
     3061 ggatgttcgg attcttatac taaaaagatt tatttactta aatatttaat ttagttatga
     3121 ctaaacagaa gaaattcatc acatgtgatg gtaaccaagc tgcagcacat atctcgtata
     3181 tgttctctga agtagcagct atctacccca tcactccttc ttcgactatg gctgagtacg
     3241 tagacgaatg ggctgccgca ggacgtaaga acatcttcgg cgaaacagta ttggtacagg
     3301 aaatgcaatc tgaaggtggt gctgccggtg cagttcacgg ttctcttcag gctggtgcat
     3361 tgactactac ttacactgct tctcagggtc ttcttttgat gatccctaac atgtacaaga
     3421 ttgccggtga attcttgcct tgtgtattcc acgtttctgc tcgtacactg gcttctcacg
     3481 cattgtgtat cttcggtgac catcaggacg taatgtcagc tcgtcaaacc ggcttcgcta
     3541 tgttggcaga aggttctgta caggaagtta tggatttggc aggtgttgct catctggcta
     3601 ctatcaaatc acgcgttccg ttcatgaact tcttcgatgg tttccgtact tctcacgaaa
     3661 tccagaagat cgaaatgttg gaaaacgacg acctcgctcc gctgatcgac caggaagctt
     3721 tggctgaatt ccgtgcccgt gcactgaatc cgatgaagcc ggttgcccgt ggtatggctg
     3781 aaaaccccga ccacttcttc caacatcgtg aatcatgcaa taactactat gaagcagttc
     3841 ctgctatcgt agaagaatac atgaacgaaa tttccaagat cacaggccgc aaatacggtt
     3901 tgttcgatta ctacggtgca gaagatgcag aacgcgtaat tatcgcaatg ggttctgtaa
     3961 ctgaagctgc ccgcgaagct atcgaccact tggtagcaaa cggcgaaaaa gtaggtatgg
     4021 ttgccgtaca cttgtatcgt ccgttctctg ctaaacactt cctggctgct gtacccaaga
     4081 ctgcaaagag catcgcagtg cttgaccgta caaaagaacc gggtgctaac ggcgaacctc
     4141 tttaccttga cgttaaagac tgcttctatg gcgcagaaaa tgctcctgtt atcgttggcg
     4201 gtcgctacgg tctgggttca aaagatacca ctccggcaca gatcatctct gtattcgaaa
     4261 acttggctat gccaatgccg aagaaccact tcactatcgg tatcgtagac gacgttacgt
     4321 tcacttctct tcctcagaaa gaagaaatcg ctctgggcgg tgaaggtatg ttcgaagcta
     4381 aattctacgg tctgggtgct gacggcacag taggtgccaa caagaactct gttaagatta
     4441 tcggtgacaa caccgacaaa cactgtcagg cttacttctc ttacgactcc aagaagtcgg
     4501 gtggtttcac ttgttctcac ttgcgtttcg gtgatactcc gatccgttct acttacttgg
     4561 taaatactcc gaacttcgtt gcttgtcacg ttcaggctta cctgcacatg tacgacgtaa
     4621 cacgtggttt gcgtaagaac ggttctttct tgctgaatac catctgggaa ggcgaagaac
     4681 tggctaagaa cctgcctaac aaggtgaaga aatactttgc acagaacaac atctctgtat
     4741 actatatcaa cgcaactcag attgcaatgg aaattggttt gggcaaccgt accaatacaa
     4801 tccttcagtc tgcattcttc cgtatcacag gcgtaatccc tgtagatcaa gctgttgaac
     4861 agatgaagaa attcatcgtt aagtcttacg gcaagaaggg tgaagacgtt gttaacaaga
     4921 actacgctgc tgtagaccgc ggtggtgaat acaagactct gactgtcgat cctgcttggg
     4981 ctaacctgcc ggatgatgca aaagcagaaa acaatgatcc tgctttcatc aacgaagtag
     5041 ttcgtccgat caatgcacag gacggtgact tgctgccggt atctgcattc aagggtatcg
     5101 aagacggtac ttggtatcaa ggtacttcca aatacgaaaa acgtggtgta gctgcattcg
     5161 ttcccgaatg gaatgctgaa aactgtattc agtgtaacaa gtgtgcttac gtttgtcctc
     5221 acgcttctat ccgtccgttc gtactcgatg ctgaagagca gaagggtgct aagttcgagc
     5281 aactgaaagc tgtaggtaaa gcattcgatg gtatgacatt ccgtattcag gtagacgttc
     5341 tcgactgtct gggttgcggt aactgtgccg acatctgtcc gggtaatccg aagaagggtg
     5401 gcaaggcatt gaccatgaaa caccttgaaa gccagttggc cgaagctgat aactggactt
     5461 actgcgctga aaacgtgaag agcaaacaac acctggtaga catcaaggct aacgtgaaga
     5521 actctcagtt cgcaactccg ttgtttgagt tctcaggcgc ttgctccggt tgtggtgaaa
     5581 ctccgtacgt gaaactgatt tctcagttgt tcggtgaccg tgaaatggtt gctaacgcta
     5641 caggatgttc ttctatctac tccggttcag ttccttctac tccgtacact atgaacgaaa
     5701 agggtcacgg tcctgcatgg gctaactcct tgttcgaaga cttctgtgaa tttggtctgg
     5761 gtatggaact ggctaacgaa aagatgcgtg cccgtctggt gaaagtaatg aacgaagcta
     5821 tcgcttctga ttgctgcccg gctgaataca aagaagtatt tgctgaatgg atcaacaata
     5881 tgctggatgc agaaaagact aaggaactgg ccgaaaagat cattccgatg gtagaagctg
     5941 ctaaagataa atgcaaccac tgcaagcaaa tcgctgatct gcaacaatat cttgttaaac
     6001 gcagccaatg gatcatcggt ggtgacggtg cttcttatga tatcggttac ggtggtcttg
     6061 accatgtaat cgcttccggt aaggacgtta acatccttgt attggatact gaggtttact
     6121 ctaacacagg tggtcagtct tctaaagcta ctccggtagg cgctatcgct aagtttgctg
     6181 ctgcaggtaa gcgtgtacgt aagaaagacc tcggtctgat ggctactact tacggttatg
     6241 tatatgttgc tcagattgct atgggtgctg accaggctca gactctgaaa gctatccgtg
     6301 aagctgaagc atatccggga ccatcactga tcatcgctta cgctccatgt atcaaccacg
     6361 gtctgaaagc cggtatgggt aagagccagg aagaagaaga aaaggctgtt aagtgcggtt
     6421 actggcactt gtggcgttac aaccctgctt tggaagaaga aggcaagaat ccgttccaac
     6481 tggatagcaa agaacctaac tgggaagact tccaaggttt cttgaagggt gaagttcgtt
     6541 acgcttctgt aatgaaacaa tatcctgctg aagctgaaga actgtttaaa gctgctgaag
     6601 aaaacgctaa atggcgttac aacagctaca aacgtcttgc cagagaaaac tggggagctg
     6661 atacagctga ataataagta gaaatacttt atacataata aaaggcagga atcctggaaa
     6721 cagattcctg ccttttttgt ttatatctta gaagtaacga ttacttctca cgaagatatt
     6781 cattaaaact ctaaagatat gatcggattt gttatttgga ttatcggttt gatactgact
     6841 ttcagagctg ccatagagat ttggaatata aatgcggctg tagagaaaag acttatagcg
     6901 attgtattaa tcgttcttac cagctggctg ggactacttt tctactactt ctatggtaaa
     6961 gaaagaatgg caggatggtt gaagtagtgt ttgcatatca atctttctca ggaatccaac
     7021 tgtttaccag ttcctgatgt tcttccatcc attgacgggc agcctgtctt tccgttgtct
     7081 gcgcctcttc cagagcagtc attaaagagc tgatttccgc atctgtcaga cgaatgttgc
     7141 ccaaaagttc ggcagcaaaa gggtctttct cgctaaaacc tttccatgct atggtatgaa
     7201 tggattccgt atttccatat atcagcttcg ggtcctgaag aactttcagc ttgaaacggt
     7261 cgaacatcca gtgaggcgtc catcccgtca cgacaatcca gtctttctta tcaatcgctt
     7321 tctttaggga agcagtcatg gcaggtccgc tcgaagtcat cagtttataa tccaatccat
     7381 agtctttgat ggcctgatcg gtagctttca taataccggc tccggcatca ataccgacaa
     7441 tctgaccgga gaaacgttcc ttttccgcgt tcagttcttc gattgagttg atcgtaacgt
     7501 aatccggaat caccagcccg atacgggcac catcataaat atccccgata acttcgagtt
     7561 tatccccgta ttgtttcata taatcttcca tagtgacagg catccagaca tccataaata
     7621 cgtctgcttt cttacgggag atagaggtaa atataggtgc aaggtcggca ttcagcaact
     7681 ttacatcgta cccctgatct tcaaaaatcg ctttggcaag gtttgtcatt gcaatacctt
     7741 ccgaccagtt ggcataagcg atacttatct tcttactctt tccgttgtct ccgcaggaaa
     7801 cgaaggttaa gagtatgccg gcaataaaca ttgccgcaat catttttatc ttattcattg
     7861 attattcctt tctttggtgt gattcttatt tctttttact ttttctgtta tctgccatac
     7921 cctgagtgat gcggtccagc acgatcgcca atatcacgac tgcgataccg ccttcaaatc
     7981 cgagtccgat tttcatttgg gtgatacctt tcagcacgat ttctcccaac cctcccgcag
     8041 aaatcatggc ggcaatcact accatcgaaa gtgacatcat gatcgtctga ttgattcccg
     8101 tcagaatagt aggcaatgcc aaaggcaatt gcaccttata aagaagctgc cagggagtag
     8161 ctccaaaaga acgggaggct tctactacat ttttaggaac ctgacgaatg cccagaccag
     8221 tcagacgaac cacaggaggc attgcaaaga tgatggtggc aaaagctccc ggcacagttc
     8281 ccaatccgaa gaatagaacg gcaggaatca gatagacaaa ggcaggcatt gtctgcataa
     8341 agtcgaggac agggcgcatt atcttgttac aacgatcact gttggcagtc cagattccca
     8401 acggaacgcc taaaagcaat gccagacaag tggaagaaag taccaatgcc aatgtctgca
     8461 tcgtttcttc ccaaaagccc atgccgtaaa taagcaataa acccaagagg gtaaatacgg
     8521 ctgtcccctt acccgactta aaccaggcga gcgcagccag cactgcaatt gtgatataaa
     8581 aaggtattcc aaacagtacg tgctgaaaac cgtctatgaa tcctccgatc cccatgctga
     8641 gagcatcaaa aaaggaagca aaatgttctg tgagccaatt aatggcagtc tctatatatt
     8701 gtccgatatt tatcataatt ctattgcgtt ttgaatgatt tcattaattt cttctttatc
     8761 ttttcccgtt acttcgatga tcaatgagga aagtggcact acgccttcaa actcccgatt
     8821 ctcatttacg acccagattg gcgagttcgt ttttgtcatc aacggaagaa tatcttccag
     8881 caccgtatca cccagcactg aatgaacttc atgccttact acggactcga tggagcggat
     8941 ttgctctttt cgtagtttca gcaagtcatt caaccgcacc tctcctacta acagattatt
     9001 ggaatcgact accggaagaa cggtcagatt ccgttcgcgc atcttacgga tcagcacctc
     9061 cgggccttct ttcttcaaac gtgccactat gggtttatct accataacag aggaagctgt
     9121 tataatcttg cttcgatcta cattctccac aaatcgttct acataagcgt tggcaggttc
     9181 ggtcaggatt tcttccgatg taccgatttg tacaatttct ccatccttca tgatagcaat
     9241 ccggtcaccc aatttaatcg cttcactcag gtcgtgagta ataaagacaa tcgttttttt
     9301 catcttcgac tgcaaagtca gcagttcatc ctgcatctgc acacggatca aaggatcgag
     9361 tgccgagaag gcctcatcca tcaacaggac ttcgggatta ttggccaaag cccgcgccag
     9421 cccgacacgc tgctgcatcc cacccgacag ttcacttacc atctgattct cgtagccttt
     9481 cagccccacc agttgcatac tttccatcgc tttctgctcc cgttctccct tttttactcc
     9541 ctgtagttcg agcccgaaag ctatattatg caagacagaa cggtgaggaa gcagaccgaa
     9601 gttctgaaag accatagcca gttctttccg gcgaatctgc aacagttcct tatccgacac
     9661 tttggctatg tctgttccat tgataatcac ttctccggaa gtagggcgta tcaaacggtt
     9721 gatgcagcgg agtaaagtgg actttccact accggacagc cccataatga cgaatatttc
     9781 gccttcatta atggaaagat tcgcatcttt caccgcaact gtacatccgg tcgctttcaa
     9841 tatttcactt tttgttttac cttctttcaa catcttcaaa gccttctgct tctcattgcc
     9901 aaaaaccaga tagagatctt taatttctat tttactcata caataaaatg gtttaggtta
     9961 ttaaaataat atacacagca agacaagaac aaacgataac aggaatcttt ctttatatcg
    10021 tataaagttc tgatttaaat aagggacaaa taacaatgaa tcccgaaata attaataaaa
    10081 tgattattga cagactgagt aattaaaaaa ggaatagaat ttgataagat aatcctttca
    10141 acgaatagca aaaaatagca tttttatgta taaaaacagc ctgttccagt atcttgctgg
    10201 cacaaagata caaaaaacgg attaaacata caaattatat tcaaaatccg gggcatacag
    10261 agggctttat ttgtaatgat atggaaagtt tccgggtaat attcccctat cactcagcaa
    10321 aatagaacaa accggcagat aaatataaaa taagtttgaa tatttcactt aaacaccgta
    10381 tatttggcgt caataactaa actagattta tatgttcaac agggctatta caattttcct
    10441 ggggaaggat aattgtcatt acacaacaaa agaaaaacaa acaggtactg ccacactaga
    10501 cgacaaaagc caagtacagt tccttagtaa aaagaacccc aaaatgccgt ttttctatag
    10561 ccggcggaat ctctacatga taggtttcct gctcgctttt atagtgactc tgctcgaatt
    10621 tatacgagga cggcatcaaa actttatggt cttctcggac gctactcaat tcttctggca
    10681 aggcatcagc ccatacacaa ctgaatttgt agaagctcac ggacgctact tcctttattc
    10741 tccagttttc acggtattgt tcgctccgtt tgcgtatctg cctgcatggc tgggaccttt
    10801 cgcgtggaat ctattcaatt attcgctgtt ctttatggcg atcttcacgc tgccccaaca
    10861 attcacccag cagcagaaat gccgtatgtt cctttttctg ttactgattt taggacaaag
    10921 tttactttca tttcagtata acataacggt agcctattta ttcttattcg cctatacgtt
    10981 attggaaaaa gaccgtggat ttctggctgt tctgttaatc atgatttcgg gatgtaccaa
    11041 agtatatgga attttcgaac tggcattgtt gctgtgctat cctcacgtat ggcgtaactt
    11101 tggctatgcc gttacaatgg gcattgtatt gcttgcatta ccgttaatca aaatagctcc
    11161 tgcagatttg ctcccctatt atgaagaatg gtgccatagt cttgctgttc atcagtccgc
    11221 cggagcttat gattcatttt tctatgcccg ccccattgca gcatggacat tgccacactt
    11281 ccgtgcactt cagataggaa tgctcggctt gctgactctg ctctttttgg ggaatttccg
    11341 caaatggtcg tcttttgcct tccgtgccca ggctttgggc attctcatgg gctgggtagt
    11401 attactgagt gactccgccg agaagcatac ctatattatc gcattggcag gtttcatgct
    11461 ctggtattgg agcagaccaa cacgtaccgc aacagacaag attctatttt ggtgctgttt
    11521 tgtgctgtta tgtatcgttc ctatcgacat attcgtccct atacccatca gagatttcat
    11581 taccaggacc ttatggcttc atgtatgggt tttctttatt gtatggatac ggatgatatg
    11641 gcttaccttc cttgcatcct tcattcatcc acgtgccaca aatgttcttt cagattaacg
    11701 catccgttag ctttgaaaga aacttcttct gccagcaaga gttgtttttg ttccacccaa
    11761 ccgggcacca gccttccggt ggaatttaca actctatggc agggaatgga taattcatcc
    11821 ggcacttctt tcaatgcacg tcccaccatc cgcgagcatt ggggtgcccc caacagcaaa
    11881 gcaatacctc cataagtaga tacttttccc acaggtatct gggatacgac ttcgtacact
    11941 tccttccgaa aggattcgga aaagctctct ttatctactt tataatcttt catatatccc
    12001 tctttacgat atcaatgaaa tcatcctttc cttttcagga aatctgtcgg gctctctcca
    12061 aactgctctt tatagcactt ggcgaaataa gaaggtgaac tgaaaccgac ttcataacca
    12121 atctccgcta cggtcatgtc cgaagaagca agcaaagaag ctgccttctt caaacgggcg
    12181 atacggagca attcattcgg agagtagtta gtcaatgatt taatcttgcg ataaagctgc
    12241 acacggctta gtcccatgtc tttgcccaag tcctccacat tcaaaccgga gtctcccatt
    12301 ttctcttcaa tcaatgactt gaatctttct acaaaatcct tgtccatatc gcagacatct
    12361 tcttttgcca atgtctgccc gtcaccaaag aactgtttca gacgacggtg agaatcgatc
    12421 agattgcgga cacgtgccag caacagctgt gaactgaacg gctttgaaat ataagaatcc
    12481 gcaccaccgt catatccctg aatacgctgt tcgtccagtg aacacgctgt cagcagaata
    12541 accggaatat gacaggtctg taactcactt ttcagccggc ggcaacattc aatgccatca
    12601 atgcccggca tcatcacatc agaaatgatc aggtccggaa catacttcat agccttacgg
    12661 attccttcgg agccgtctgc cgcttcaatc accgtatagt ctgtatgcaa caacgtatgg
    12721 acatacgaac ggatatcctc attatcatca ataatcagta cggacggttt ggaagagtca
    12781 tatccttttt ccagttcttc ctcttccgcc aatagaacat ctgttgtacg ggaatccgca
    12841 gaaacaaggg tggtatccgg ttcggcagca acagcctcac aagactgtac aggcagttca
    12901 acggtaaaga ccgtgccctg tttctcatcg ctctctacgg agatcatacc accgtgcatt
    12961 tctacgaagg cttttaccaa tgccagtccg attcccgaac cggtatggtg catatcgatc
    13021 ttatagaaac ggtcgaatac attgcgaata tgttcggcag aaatcataga accggtattt
    13081 gccaccgtga aacgtatcca tcgcttgtcc tctttactaa gggaagacag acggacggct
    13141 attttcccgt tttccggtgt aaacttaaag gcattggaca gaagattgaa ataaatacgt
    13201 tccagcttct ccatgtctgc cagtgtatga taatccgtat ccggcatact atcaaaagaa
    13261 aaatggatat gcttcttacg ggctgccgcc tgaaaagact cattccatcc ttcgaaagaa
    13321 gaaaggacat ccaccgtaac cggagtatat tccatcttgc cgttttcata tttacggaaa
    13381 tccagaatct gattgaccag acgcagaaga atgttcacat tccgctgaat cagcatgagc
    13441 atccggtgct gatctccgct cagtgtcttg tccgccaaca aatgttctac cgggtcggca
    13501 accaatgtca acggagtacg gaagtcgtga gaaatattgg tgaaaaagac cagcttggca
    13561 tgggtagctt cttccagttg atgagagagc tgtatcaatt ggtcacgctg ttcttccagt
    13621 ttgtcacgct gctcttccaa ttgctgcttc tgcttaaaaa gctctttatt caagcgattc
    13681 ttagagcgga gtgatttata aacgaccaat aataagccgg ctaccaataa aaggataatc
    13741 agactgccgt ataaaacgac ctgttgtgta gctacctgag agagatagcc accgatacgt
    13801 ccgttgagcg tttcaatctt tttgtcgagt tcggaaatgt gtgtggtctg caactgcatg
    13861 acgtgtgcgt tggtacggtc cacaacagcg gtattcatca ccgtttcttt gggatagggt
    13921 ttcttctcca gaatgtccat agccagttgc agtaccttat cgccattggt cggatagata
    13981 aaggtggcat ccagcacact gtccagtacc agttccagtc cgtttccctt acccggcaag
    14041 gcatctatgc cgacaaaaat catttccttc tcccgccctg ccatctttgc tgcctgatag
    14101 gcacccggag cgatacggtc attatgggca tacacagcat caatcttagg atgcctccga
    14161 agcatactat ccatttctat ctctgccgga ccacgttccc acgcagcatc cgctttatca
    14221 atcagcttta tatccgggaa tttactgatg gcagccataa atccctgatg ccgttccatt
    14281 gcaggagtcg aaccgctcaa tcctgtcagt tctactatat ttcccttccc tttcagactg
    14341 gaggcaatat agtttcctac cgaacgaccg atttcataat tatcggctcc gatataggca
    14401 gtatatttat ccgaaagaat cttccggtct acaagaataa cggggatgcc tttctgataa
    14461 gcttcttcta caatcggagt cataggagca gcttcgttag cggaaataat cagcagatcg
    14521 actccttcgt ccataaaata atggacatct tccgcctgct tactgttatc atcccctgcc
    14581 gaacggattt ccaccgaaac accattataa aacatcgctt cccgaagaat ctcatcattc
    14641 atcttatgtc gccatgaatc atcgctgcat tgagccaccc caatacgaaa acggggtgta
    14701 tcctgccggc aagccgtcat cccgattaaa ccaaacagca ccagcatcca cttcagatat
    14761 ctcatcgtct tcatccatct catcatttca tagttctttc tgtaatccaa ttaagaacaa
    14821 aaataagaaa taatactgta aagttctcta acttcagcta tttattattc taaaaagaag
    14881 gaaagcagtc ctctttcaga ccatcggaaa gtattaacaa aagtataaag cgtaaaacaa
    14941 acacttaatc aatgttataa aacatagcgt tttacttgga taatttgcag atttcacaga
    15001 agtccgtatc tttgcactgt gtttttcata gtattagatt taaggttaac aaaggttgga
    15061 gcaaggcgtt gctccttttt ttatgctctg acctttcatc taccggttag ttttcatccc
    15121 attccttttc cagtttacca tcaatagtgt agcgtttcca tcgtcctaca cggtgaccat
    15181 tcttatattc cccacattca cgaagctggt cattctttac ataacgagct tcgaacggtc
    15241 cgttctgcct tccgttcaca taggtagaag tttcccaata atcaaagcgg ttgctcacta
    15301 tcagccgtcg ttccttgcca tgcaatctgc cggcctgata ggtagcttca tatctcaatt
    15361 caccattttc caaattatat tcacggtata aaccgtcttt acgatcgttc ttcatataat
    15421 attctttctg ccttacccca cttccgttgg caaatgagac atggagtcca tcttcttttc
    15481 catccagata ggtttcaatc atcagcgtat ctccgctttc agcaaaagta gtccaacgac
    15541 cattcttctt tccattctta taactaccca gtatacgtgg cgagccaaac gtaaacacgg
    15601 acgaatattc accgtcctga aaaccttctt cattgaaata aacggtctca tacaaatcat
    15661 atgtaccttt cagaaaagta tactgtttgc ctacctgctt cccgtccttg taattatgct
    15721 ctttccgcaa agtaccgtca gattcgtacg acagttgctt cccgtgctct ttccccatcc
    15781 ggaagtttct ttcactttcc acttttccgg tagtaaagta acttttgctc gtaccgtcca
    15841 gcttaccttc cttataggac ttttcttctt tcagcttacc gtcaaacttg gagttaatct
    15901 tgaagaggcc atccttccgc ccttctttat aacttccttc cgttattaat atattgtcca
    15961 catattcttt gtatccgcca tcataaaaac catctttaaa agatgccagc acataggcgg
    16021 aatgataacc atctatgatg cgatgttcgc cattcaatgc tttttccgtt ttcagttcct
    16081 gaaacaacag tctgccatcg cctacattaa caacagatac ctgatcgatc ttatattcct
    16141 tttgcgcaaa caaaggaaga gcaagatata aaaacaaaaa tacgttccag ctttttgatc
    16201 tgaggaagtt cgaaatgtgt ttcataaagt agttttctct ttttgattta ttatttaaaa
    16261 acctgccgca aagataggca atcggcttat aaaacaaggc aagaaagagg gggacaatta
    16321 gaaaaaagaa catctgttat tatcattcta ataattaaca gattaagtag taaatcaaaa
    16381 cacagggaag ggggacattt actgaaataa gaaacagaaa agaagatgtg tcaaaagtaa
    16441 ctaaatttcc ctccttcagg aaggaggaga gtttagttgc ttttga
//
