LOCUS       c00043_gnlPro..        16648 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MOMGNMEH_45.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:02:07
            Original ID  :: gnl|Prokka|MOMGNMEH_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16648
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16648
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3199:6757](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3200..6757
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16648
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16648
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(627..1781)
                     /locus_tag="ctg43_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1961..3166
                     /locus_tag="ctg43_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3200..6757
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6882..7070
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7081..7941)
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7969..8799)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg43_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8796..10022)
                     /locus_tag="ctg43_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10495..11781
                     /locus_tag="ctg43_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11744..12076)
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12104..14857)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15190..16416)
                     /locus_tag="ctg43_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 agggttagta atatttctag tcaacacata gcagctatta gagataaaca agtcaaccat
       61 tattagggaa gtacacagta ttaccacaat atgacttttc cgatgttcac caattccaat
      121 ttagcagtat cttcaaagag tttccattgc ttgaaaccag agtttcatcg gtgtgaaact
      181 gtagtttcat cggtgagaaa ctagagtttc atacgcttga aactttagtt ccaaacgctc
      241 gaaactatct gaaactactg ttgatttgat tgacttaacc gcatgttcca atcacattga
      301 acgcatcagc tacttcaata gtactgctct ctctgaaaac attaaatcat atatcagtca
      361 ataatacata aattatcagt ccttaatact tgatttctca attattaata tctgagaaat
      421 caaacgttaa cagttgagat atcagatatt aacatcctgt aaatcaaaga ataacacagt
      481 aaaaacggta tttatcagga cgatgcagag tgagagcaag tccttgctct cactctgcta
      541 ccactggatc tctaacagct aaaacatcga tgaataaagg gatacagacg aactgttaga
      601 gcatgagagc aaaagcacta tctttttcac tgggggagag taagcaaaag aaacgcacga
      661 taccggcttt gaggcgtcac cggtactaac ggcaaatatc cggcacacac ccgattattc
      721 tctacggaca aagggaacga agccgacatc tgccgatgtt cctccaaagc ctgaccggct
      781 aaaggataat aatcaatccg aaaaactcct tccgcatccg cagccaaata acgatccgtc
      841 aagagccatg ccaccacccc catattcatt cgcagattaa tttcgacaca aggatgaatc
      901 cggtaaacag gcgcttcatc cggaaaatga caaatcatca tatccactcc caagtatcca
      961 tgataaaagc caccgaacaa agctgacaat tcttcttcca aacgagtccg cagcctgata
     1021 aattcttctt gtggcacata agccgatagt ttctgcagaa tcttctcgtc agacagcaag
     1081 tcattccctg catacatccc actcccaccc gtgtggaaga ccgaatatcc ggcaaaaaca
     1141 acccttcctc tcccgtcagc ataaaactcc atagcgaaat cttccacctt attatatata
     1201 ggttcgccta ccaccccacc ctgagaagca gcgacacggg cacaccaacc ggaaataaaa
     1261 gtagtaaata tgcctttaca ccaattcaat cctttcccgc ttccggaaag cggagctttt
     1321 aacaagcacg cttcccgccc ttcgacgaac gcactgcact ccgccaaagt actcaaataa
     1381 aaagattctc cacagaagta ttcattcaac cgcaacccag gcaacaactt taccgcctgc
     1441 agacgatgcg aatgctctct cagaatattc atataatccg cagaaggcag ctccgtctga
     1501 tctgccccca atgtcatcaa acgcttccgc aaagcagggt cccaccccca cggagagaac
     1561 ttccggtctt taccgtcagc cacttccggt tccgtcaaca aggccacatc catgcccaaa
     1621 agttcactct ttgttttcag gaagtccgca ttataagcag acggtgcaag caccgcactt
     1681 cccgcttcgg cataccacat aggaagcaac gccaggtcac tcgccatctg tcgggcggaa
     1741 gccggcgcca tatagttcgt ctcaccgctt gccaacgcca tatcatgctc cggattgaat
     1801 atataaacag gtcttttcgt catgtcaaag atggattcaa cacattattc tgcaaatata
     1861 tacaggaaat aatcaggaac ttacacaata aagagaaact tataaattaa agcacatttt
     1921 tgctatctct actttgcaaa tcctaaaaaa agcactatat ttgccagccg aaaaacaaag
     1981 aaacgaaatg gaatcattct atcgcacaca cgcctacctc gttgagcaca ccaatgcccc
     2041 cgttcgccgc gatcttatgg acgagatcga ctggagtgac cgtctgattg gtatcaaagg
     2101 gacacgtggc gtgggaaaaa ccactttcct cctgcagtac gccaaagaga aattcggcac
     2161 cgaccgttcc tgtctgttca tcaatatgaa caacttttat ttctccggtc acagccttgt
     2221 tgacttcgcc aacgagtttc agaaacgtgg cggaaaagta ctgctgatcg accaggtgtt
     2281 caaacatccc gaatggagca aagagctacg aatgtgctat gaccgtttcc ccagcctgaa
     2341 gattgtcttc accggttctt ccgtcatgcg actcaaagag gaaaacctcg aattgcgtga
     2401 cattgcgaaa agttataacc tgcgcggatt ctctttccgt gaatttctga acctgcagac
     2461 aggaatgaaa ttccgggcat acagcctcga agaaatcctc agtacacatg aacagatagc
     2521 caaaggagta ctttccaaag tacgaccgct ggattatttt caggattacc tgcatcatgg
     2581 tttctaccct ttcttccttg aaaaacgtaa tttctcggag aatctgctga aaacaatgaa
     2641 catgatggta gaagtggata tcttgctgat caaacaaatt gagctgaaat atctttcaaa
     2701 gataaaaaaa ttactatatt tgttggctgt ggacggaccg aaagctccga acgtgagcca
     2761 actggcaagt gacgtacaga catcccgcgc tacggtaatg aactatatca agtatctggc
     2821 agacgcgcgt ctgattaatc tggtttaccc gaaaggagaa gaattcccaa agaaaccgtc
     2881 aaagattatg atgcacaact ctaacctgat gtactccatt tatccggtga aagtggaaga
     2941 acaggatgta ctcgacacgt tcttcgttaa cactttatgg aaagaccata aggtacataa
     3001 aggagataaa aacgtctctt tcatggtaga cgaagtgatg ccgttcaaaa tttgtgcgga
     3061 aggtacaaaa ataaagaata acccggacgt gacgtatgcg ttgcaaaagg ctgagatagg
     3121 ccgcggcaac caaatacctc tttggatgtt cggattctta tactaaaaag atttatttac
     3181 ttaaatattt aatttagtta tgactaaaca gaagaaattc atcacatgtg atggtaacca
     3241 agctgcagca catatctcgt atatgttctc tgaagtagca gctatctacc ccatcactcc
     3301 ttcttcgact atggctgagt acgtagacga atgggctgcc gcaggacgta agaacatctt
     3361 cggcgaaaca gtattggtac aggaaatgca atctgaaggt ggtgctgccg gtgcagttca
     3421 cggttctctt caggctggtg cattgactac tacttacact gcttctcagg gtcttctttt
     3481 gatgatccct aacatgtaca agattgccgg tgaattcttg ccttgtgtat tccacgtttc
     3541 tgctcgtaca ctggcttctc acgcattgtg tatcttcggt gaccatcagg acgtaatgtc
     3601 agctcgtcaa accggcttcg ctatgttggc agaaggttct gtacaggaag ttatggattt
     3661 ggcaggtgtt gctcatctgg ctactatcaa atcacgcgtt ccgttcatga acttcttcga
     3721 tggtttccgt acttctcacg aaatccagaa gatcgaaatg ttggaaaacg acgacctcgc
     3781 tccgctgatc gaccaggaag ctttggctga attccgtgcc cgtgcactga atccgatgaa
     3841 gccggttgcc cgtggtatgg ctgaaaaccc cgaccacttc ttccaacatc gtgaatcatg
     3901 caataactac tatgaagcag ttcctgctat cgtagaagaa tacatgaacg aaatttccaa
     3961 gatcacaggc cgcaaatacg gtttgttcga ttactacggt gcagaagatg cagaacgcgt
     4021 aattatcgca atgggttctg taactgaagc tgcccgcgaa gctatcgacc acttggtagc
     4081 aaacggcgaa aaagtaggta tggttgccgt acacttgtat cgtccgttct ctgctaaaca
     4141 cttcctggct gctgtaccca agactgcaaa gagcatcgca gtgcttgacc gtacaaaaga
     4201 accgggtgct aacggcgaac ctctttacct tgacgttaaa gactgcttct atggcgcaga
     4261 aaatgctcct gttatcgttg gcggtcgcta cggtctgggt tcaaaagata caactccggc
     4321 acagatcatc tctgtattcg aaaacttggc tatgccaatg ccgaagaacc acttcactat
     4381 cggtatcgta gacgacgtta cgttcacttc tcttcctcag aaagaagaaa tcgctctggg
     4441 cggtgaaggt atgttcgaag ctaaattcta cggtctgggt gctgacggta ctgtaggtgc
     4501 caacaagaac tctgttaaga ttatcggtga caacaccgac aaacactgtc aggcttactt
     4561 ctcttacgac tccaagaagt cgggtggttt cacttgttct cacttgcgtt tcggtgatac
     4621 tccgatccgt tctacttact tggtaaatac tccgaacttc gttgcttgtc acgttcaggc
     4681 ttacctgcac atgtacgacg taacacgtgg tttgcgtaag aacggttctt tcttgctgaa
     4741 taccatctgg gaaggcgaag aactggctaa gaacctgcct aacaaggtga agaaatactt
     4801 tgcacagaac aacatctctg tatactatat caacgcaact cagattgcaa tggaaattgg
     4861 tttgggcaac cgtaccaata caatccttca gtctgcattc ttccgtatca caggcgtaat
     4921 ccctgtagat caagctgttg aacagatgaa gaaattcatc gttaagtctt acggcaagaa
     4981 gggtgaagac gttgttaaca agaactacgc tgctgtagac cgcggtggtg aatacaagac
     5041 tctgactgtc gatcctgctt gggctaacct gccggatgat gcaaaagcag aaaacaatga
     5101 tcctgctttc atcaacgaag tagttcgtcc gatcaatgca caggacggtg acttgctgcc
     5161 ggtatctgca ttcaagggta tcgaagacgg tacttggtat caaggtactt ccaaatacga
     5221 aaaacgtggt gtagctgcat tcgttcccga atggaatgct gaaaactgta ttcagtgtaa
     5281 caagtgtgct tacgtttgtc ctcacgcttc tatccgtccg ttcgtactcg atgctgaaga
     5341 gcagaagggt gctaagttcg agcaactgaa agctgtaggt aaagcattcg atggtatgac
     5401 attccgtatt caggtagacg ttctcgattg tctgggttgc ggtaactgtg ccgacatctg
     5461 tccgggtaat ccgaagaagg gtggcaaggc attgaccatg aaacaccttg aaagccagtt
     5521 ggccgaagct gataactgga cttactgcgc tgaaaacgtg aagagcaaac aacacctggt
     5581 agacatcaag gctaacgtga agaactctca gttcgcaact ccgttgtttg agttctcagg
     5641 cgcttgctcc ggttgtggtg aaactccgta cgtgaaactg atttctcagt tgttcggtga
     5701 ccgtgaaatg gttgctaacg ctacaggatg ttcttctatc tactccggtt cagttccttc
     5761 tactccgtac actatgaacg aaaagggtca cggtcctgca tgggctaact ccttgttcga
     5821 agacttctgt gaatttggtc tgggtatgga actggctaac gaaaagatgc gtgcccgtct
     5881 ggtgaaagta atgaacgaag ctatcgcttc tgattgctgc ccggctgaat acaaagaagt
     5941 atttgctgaa tggatcaaca atatgctgga tgcagaaaag actaaggaac tggccgaaaa
     6001 gatcattccg atggtagaag ctgctaaaga taaatgcaac cactgcaagc aaatcgctga
     6061 tctgcaacaa tatcttgtta aacgcagcca atggatcatc ggtggtgacg gtgcttctta
     6121 tgatatcggt tacggtggtc ttgaccatgt aatcgcttcc ggtaaggacg ttaacatcct
     6181 tgtattggat actgaggttt actctaacac aggtggtcag tcttctaaag ctactccggt
     6241 aggcgctatc gctaagtttg ctgctgcagg taagcgtgta cgtaagaaag acctcggtct
     6301 gatggctact acttacggtt atgtatatgt tgctcagatt gctatgggtg ctgaccaggc
     6361 tcagactctg aaagctatcc gtgaagctga agcatatccg ggaccatcac tgatcatcgc
     6421 ttacgctcca tgtatcaacc acggtctgaa agccggtatg ggtaagagcc aggaagaaga
     6481 agaaaaggct gttaagtgcg gttactggca cttgtggcgt tacaaccctg ctttggaaga
     6541 agaaggcaag aatccgttcc aactggatag caaagaacct aactgggaag acttccaagg
     6601 tttcttgaag ggtgaagttc gttacgcttc tgtaatgaaa caatatcctg ctgaagctga
     6661 agaactgttt aaagctgctg aagaaaacgc taaatggcgt tacaacagct acaaacgtct
     6721 tgccagagaa aactggggag ctgatacagc tgaataataa gtagaaatac tttgtacata
     6781 ataaaaggca ggaatcctgg aaacagattc ctgccttttt tgtttatatc ttagaagtaa
     6841 cgattacttc tcacgaagat attcattaaa actctaaaga tatgatcgga tttgttattt
     6901 ggattatcgg tttgatactg actttcagag ctgccataga gatttggaat ataaatgcgg
     6961 ctgtagagaa aagacttata gcgattgtat taatcgttct taccagctgg ctgggactac
     7021 ttttctacta cttctatggt aaagaaagaa tggcgggatg gttgaagtag tgtttgcata
     7081 tcaatctttc tcaggaatcc aactgttcac cagttcctga tgttcttcca tccattgacg
     7141 ggcagcctgt ctttccgttg tctgcgcctc ttccagagca gtcattaagg agctgatttc
     7201 cgcatctgtc agacgaatgt tgcccaaaag ttcggcagca aaagggtctt tctcgctaaa
     7261 acctttccat gctatggtat gaatggattc cgtatttcca tatatcagct tcgggtcctg
     7321 aagaactttc agcttgaaac ggtcgaacat ccagtgaggc gtccatcccg tcacgacaat
     7381 ccagtctttc ttatcaatcg ctttctttag ggaagcagtc atggcaggtc cgctcgaagt
     7441 catcagttta taatccaatc catagtcttt gatggcctga tcggtagctt tcataatacc
     7501 ggctccggca tcaataccga caatctgacc ggagaaacgt tccttttccg cgttcagttc
     7561 ttcgattgag ttgatcgtaa cgtaatccgg aaccaccagc ccgatacggg caccatcata
     7621 aatatccccg ataacttcga gtttatcccc gtattgtttc atataatctt ccatagtgac
     7681 aggcatccag acatccataa atacgtctgc tttcttacgg gagatagagg taaatatagg
     7741 tgcaaggtcg gcattcagca actttacatc gtacccctga tcttcaaaaa tcgctttggc
     7801 aaggtttgtc attgcaatac cttccgacca gttggcataa gcgatactta tcttcttact
     7861 ctttccgttg tctccgcagg aaacgaaggt taagagtatg ccggcaataa acattgccgc
     7921 aatcattttt atcttattca ttgattattc ctttctttgg tgtgattctt atttcttttt
     7981 actttttctg ttatctgcca taccctgagt gatgcggtcc agcacgatcg ccaatatcac
     8041 gactgcgata ccgccttcaa atccgagtcc gattttcatt tgggtgatac ctttcagcac
     8101 gatttctccc aatcctccgg cagaaatcat ggcagcaatc actaccatcg aaagtgacat
     8161 catgatcgtc tggttgattc ccgtcagaat agtaggcaac gccaaaggca attgcacctt
     8221 ataaagaagc tgccagggag tagctccaaa agagcgggag gcttctacta cgtttttagg
     8281 aacctgacga atgcccagac cggtcagacg aaccacagga ggcattgcaa agatgatggt
     8341 ggcaaaagct cccggcacag ttcccaatcc gaagaataga acggcaggaa tcagatagac
     8401 aaaggcaggc attgtctgca taaagtcgag gacagggcgc attatcttgt tacaacgatc
     8461 actgttggca gtccagattc ccaacggaac gcctaaaagc aatgccagac aagtggaaga
     8521 aagtaccaat gccaatgtct gcatcgtttc ttcccaaaag cccatgccgt aaataagcaa
     8581 taaacccaag agggtaaata cggctgtccc cttacccgac ttaaaccagg cgagcgcagc
     8641 cagcactgca attgtgatat aaaaaggtat tccaaacagt acgtgctgaa aaccgtctat
     8701 gaatcctccg atccccatgc tgagagcatc aaaaaaggaa gcaaaatgtt ctgtgagcca
     8761 attaatggca gtctctatat attgtccgat atttatcata attctattgc gttttgaatg
     8821 atttcattaa tttcttcttt atcttttccc gttacttcga tgatcaatga ggaaagtggc
     8881 actacgcctt caaactcccg attctcattt acgacccaga ttggcgagtt cgtttttgtc
     8941 atcaacggaa gaatatcttc cagcaccgta tcacccagca ctgaatgaac ttcatgcctt
     9001 actacggact cgatggagcg gatttgctct tttcgtagtt tcagcaagtc attcaaccgc
     9061 acctctccta ctaacagatt attggaatcg actaccggaa gaacggtcag attccgttcg
     9121 cgcatcttac ggatcagcac ctccgggcct tctttcttca aacgtgccac tatgggttta
     9181 tctaccataa cagaggaagc tgttataatc ttgcttcgat ctacattctc cacaaatcgt
     9241 tctacataag cgttggcagg ttcggtcagg atttcttccg atgtaccgat ttgtacaatt
     9301 tctccatcct tcatgatagc aatccggtca cccaatttaa tcgcttcact caggtcgtga
     9361 gtaataaaga caatcgtttt tttcatcttc gactgcaaag tcagcagttc atcctgcatc
     9421 tgcacacgga tcaaaggatc gagtgccgag aaggcctcat ccatcaacag gacttcggga
     9481 ttattggcca aagcccgcgc cagcccgaca cgctgctgca tcccacccga cagttcactt
     9541 accatctgat tctcgtagcc tttcagcccc accagttgca tactttccat cgctttctgc
     9601 tcccgttctc ccttttttac tccctgtagt tcgagcccga aagctatatt atgcaagaca
     9661 gaacggtgag gaagcagacc gaagttctga aagaccatag ccagttcttt ccggcgaatc
     9721 tgcaacagtt ccttatccga cactttggct atgtctgttc cattgataat cacttctccg
     9781 gaagtagggc gtatcaaacg gttgatgcag cggagtaaag tggactttcc actaccggac
     9841 agccccataa tgacgaatat ttcgccttca ttaatggaaa gattcgcatc tttcaccgca
     9901 actgtacatc cggtcgcttt caatatttca ctttttgttt taccttcttt caacatcttc
     9961 aaagccttct gcttctcatt gccaaaaacc agatagagat ctttaatttc tattttactc
    10021 atacaataaa atggtttagg ttattaaaat aatatacaca gcaagacaag aacaaacgat
    10081 aacaggaatc tttctttata tcgtataaag ttctgattta aataagggac aaataacaat
    10141 gaatcccgaa ataattaata aaatgattat tgacagactg agtaattaaa aaaggaatag
    10201 aatttgataa gataatcctt tcaacgaata gcaaaaaata gcatttttat gtataaaaac
    10261 agcctgttcc agtatcttgc tggcacaaag atacaaaaaa cggattaaac atacaaatta
    10321 tattcaaaat ccggggcata cagagggctt tatttgtaat gatatggaaa gtttccgggt
    10381 aatattcccc tatcactcag caaaatagaa caaaccggca gataaatata aaataagttt
    10441 gaatatttca cttaaacacc gtatatttgg cgtcaataac taaactagat ttatatgttc
    10501 aacagggcta ttacaatttt cctggggaag gataattgtc attacacaac aaaagaaaaa
    10561 caaacaggta ctgccacact agacgacaaa agccaagtac agttccttag taaaaagaac
    10621 cccaaaatgc cgtttttcta tagccggcgg aatctctaca tgataggttt cctgctcgct
    10681 tttatagtga ctctgctcga atttatacga ggacggcatc aaaactttat ggtcttctcg
    10741 gacgctactc aattcttctg gcaaggcatc agcccataca caactgaatt tgtagaagct
    10801 cacggacgct acttccttta ttctccagtt ttcacggtat tgttcgctcc gtttgcgtat
    10861 ctgcctgcat ggctgggacc tttcgcgtgg aatctattca attattcgct gttctttatg
    10921 gcgatcttca cgctgcccca acaattcacc cagcagcaga aatgccgtat gttccttttt
    10981 ctgttactga ttttaggaca aagtttactt tcatttcagt ataacataac ggtagcctat
    11041 ttattcttat tcgcctatac gttattggaa aaagaccgtg gatttctggc tgttctgtta
    11101 atcatgattt cgggatgtac caaagtatat ggaattttcg aactggcatt gttgctgtgc
    11161 tatcctcacg tatggcgtaa ctttggctat gccgttacaa tgggcattgt attgcttgca
    11221 ttaccgttaa tcaaaatagc tcctgcagat ttgctcccct attatgaaga atggtgccat
    11281 agtcttgctg ttcatcagtc cgccggagct tatgattcat ttttctatgc ccgccccatt
    11341 gcagcatgga cattgccaca cttccgtgca cttcagatag gaatgctcgg cttgctgact
    11401 ctgctctttt tggggaattt ccgcaaatgg tcgtcttttg ccttccgtgc ccaggctttg
    11461 ggcattctca tgggctgggt agtattactg agtgactccg ccgagaagca tacctatatt
    11521 atcgcattgg caggtttcat gctctggtat tggagcagac caacacgtac cgcaacagac
    11581 aagattctat tttggtgctg ttttgtgctg ttatgtatcg ttcctatcga catattcgtc
    11641 cctataccca tcagagattt cattaccagg accttatggc ttcatgtatg ggttttcttt
    11701 attgtatgga tacggatgat atggcttacc ttccttgcat ccttcattca tccacgtgcc
    11761 acaaatgttc tttcagatta acgcatccgt tagctttgaa agaaacttct tctgccagca
    11821 agagttgttt ttgttccacc caaccgggca ccagccttcc ggtggaattt acaactctat
    11881 ggcagggaat ggataattca tccggcactt ctttcaatgc acgtcccacc atccgcgagc
    11941 attggggtgc ccccaacagc aaagcaatac ctccataagt agatactttt cccacaggta
    12001 tctgggatac gacttcgtac acttccttcc gaaaggattc ggaaaagctc tctttatcta
    12061 ctttataatc tttcatatat ccctctttac gatatcaatg aaatcatcct ttccttttca
    12121 ggaaatctgt cgggctctct ccaaactgct ctttatagca cttggcgaaa taagaaggtg
    12181 aactgaaacc gacttcataa ccaatctccg ctacggtcat gtccgaagaa gcaagcaaag
    12241 aagctgcctt cttcaaacgg gcgatacgga gcaattcatt cggagagtag ttagtcaatg
    12301 atttaatctt gcgataaagc tgcacacggc ttagtcccat gtctttgccc aagtcctcca
    12361 cattcaaacc ggagtctccc attttctctt caatcaatga cttgaatctt tctacaaaat
    12421 ccttgtccat atcgcagaca tcttcttttg ccaatgtctg cccgtcacca aagaactgtt
    12481 tcagacgacg gtgagaatcg atcagattgc ggacacgtgc cagcaacagc tgtgaactga
    12541 acggctttga aatataagaa tccgcaccac cgtcatatcc ctgaatacgc tgttcgtcca
    12601 gtgaacacgc tgtcagcaga ataaccggaa tatgacaggt ctgtaactca cttttcagcc
    12661 ggcggcaaca ttcaatgcca tcaatgcccg gcatcatcac atcagaaatg atcaggtccg
    12721 gaacatactt catagcctta cggattcctt cggagccgtc tgccgcttca atcaccgtat
    12781 agtctgtatg caacaacgta tggacatacg aacggatatc ctcattatca tcaataatca
    12841 gtacggacgg tttggaagag tcatatcctt tttccagttc ttcctcttcc gccaatagaa
    12901 catctgttgt acgggaatcc gcagaaacaa gggtggtatc cggttcggca gcaacagcct
    12961 cacaagactg tacaggcagt tcaacggtaa agaccgtgcc ctgtttctca tcgctctcta
    13021 cggagatcat accaccgtgc atttctacga aggcttttac caatgccagt ccgattcccg
    13081 aaccggtatg gtgcatatcg atcttataga aacggtcgaa tacattgcga atatgttcgg
    13141 cagaaatcat agaaccggta tttgccaccg tgaaacgtat ccatcgcttg tcctctttac
    13201 taagggaaga cagacggacg gctattttcc cgttttccgg tgtaaactta aaggcattgg
    13261 acagaagatt gaaataaata cgttccagct tctccatgtc tgccagtgta tgataatccg
    13321 tatccggcat actatcaaaa gaaaaatgga tatgcttctt acgggctgcc gcctgaaaag
    13381 actcattcca tccttcgaaa gaagaaagga catccaccgt aaccggagta tattccatct
    13441 tgccgttttc atatttacgg aaatccagaa tctgattgac cagacgcaga agaatgttca
    13501 cattccgctg aatcagcatg agcatccggt gctgatctcc gctcagtgtc ttgtccgcca
    13561 acaaatgttc taccgggtcg gcaaccaatg tcaacggagt acggaagtcg tgagaaatat
    13621 tggtgaaaaa gaccagcttg gcatgggtag cttcttccag ttgatgagag agctgtatca
    13681 attggtcacg ctgttcttcc agtttgtcac gctgctcttc caattgctgc ttctgcttaa
    13741 aaagctcttt attcaagcga ttcttagagc ggagtgattt ataaacgacc aataataagc
    13801 cggctaccaa taaaaggata atcagactgc cgtataaaac gacctgttgt gtagctacct
    13861 gagagagata gccaccgata cgtccgttga gcgtttcaat ctttttgtcg agttcggaaa
    13921 tgtgtgtggt ctgcaactgc atgacgtgtg cgttggtacg gtccacaaca gcggtattca
    13981 tcaccgtttc tttgggatag ggtttcttct ccagaatgtc catagccagt tgcagtacct
    14041 tatcgccatt ggtcggatag ataaaggtgg catccagcac actgtccagt accagttcca
    14101 gtccgtttcc cttacccggc aaggcatcta tgccgacaaa aatcatttcc ttctcccgcc
    14161 ctgccatctt tgctgcctga taggcacccg gagcgatacg gtcattatgg gcatacacag
    14221 catcaatctt aggatgcctc cgaagcatac tatccatttc tatctctgcc ggaccacgtt
    14281 cccacgcagc atccgcttta tcaatcagct ttatatccgg gaatttactg atggcagcca
    14341 taaatccctg atgccgttcc attgcaggag tcgaaccgct caatcctgtc agttctacta
    14401 tatttccctt ccctttcaga ctggaggcaa tatagtttcc taccgaacga ccgatttcat
    14461 aattatcggc tccgatatag gcagtatatt tatccgaaag aatcttccgg tctacaagaa
    14521 taacggggat gcctttctga taagcttctt ctacaatcgg agtcatagga gcagcttcgt
    14581 tagcggaaat aatcagcaga tcgactcctt cgtccataaa ataatggaca tcttccgcct
    14641 gcttactgtt atcatcccct gccgaacgga tttccaccga aacaccatta taaaacatcg
    14701 cttcccgaag aatctcatca ttcatcttat gtcgccatga atcatcgctg cattgagcca
    14761 ccccaatacg aaaacggggt gtatcctgcc ggcaagccgt catcccgatt aaaccaaaca
    14821 gcaccagcat ccacttcaga tatctcatcg tcttcatcca tctcatcatt tcatagttct
    14881 ttctgtaatc caattaagaa caaaaataag aaataatact gtaaagttct ctaacttcag
    14941 ctatttatta ttctaaaaag aaggaaagca gtcctctttc agaccatcgg aaagtattaa
    15001 caaaagtata aagcgtaaaa caaacactta atcaatgtta taaaacatag cgttttactt
    15061 ggataatttg cagatttcac agaagtccgt atctttgcac tgtgtttttc atagtattag
    15121 atttaaggtt aacaaaggtt ggagcaaggc gttgctcctt tttttatgct ctgacctttc
    15181 atctaccggt tagttttcat cccattcctt ttccagttta ccatcaatag tgtagcgttt
    15241 ccatcgtcct acacggtgac cattcttata ttccccacat tcacgaagct ggtcattctt
    15301 tacataacga gcttcgaacg gtccgttctg ccttccgttc acataggtag aagtttccca
    15361 ataatcaaag cggttgctca ctatcagccg tcgttccttg ccatgcaatc tgccggcctg
    15421 ataggtagct tcatatctca attcaccatt ttccaaatta tattcacggt ataaaccgtc
    15481 tttacgatcg ttcttcatat aatattcttt ctgccttacc ccacttccgt tggcaaatga
    15541 gacatggagt ccatcttctt ttccatccag ataggtttca atcatcagcg tatctccgct
    15601 ttcagcaaaa gtagtccaac gaccattctt ctttccattc ttataactac ccagtatacg
    15661 tggcgagcca aacgtaaaca cggacgaata ttcaccgtcc tgaaaacctt cttcattgaa
    15721 ataaacggtc tcatacaaat catatgtacc tttcagaaaa gtatactgtt tgcctacctg
    15781 cttcccgtcc ttgtaattat gctctttccg caaagtaccg tcagattcgt acgacagttg
    15841 cttcccgtgc tctttcccca tccggaagtt tctttcactt tccacttttc cggtagtaaa
    15901 gtaacttttg ctcgtaccgt ccagcttacc ttccttatag gacttttctt ctttcagctt
    15961 accgtcaaac ttggagttaa tcttgaagag gccatccttc cgcccttctt tataacttcc
    16021 ttccgttatt aatatattgt ccacatattc tttgtatccg ccatcataaa aaccatcttt
    16081 aaaagatgcc agcacatagg cggaatgata accatctatg atgcgatgtt cgccattcaa
    16141 tgctttttcc gttttcagtt cctgaaacaa cagtctgcca tcgcctacat taacaacaga
    16201 tacctgatcg atcttatatt ccttttgcgc aaacaaagga agagcaagat ataaaaacaa
    16261 aaatacgttc cagctttttg atctgaggaa gttcgaaatg tgtttcataa agtagttttc
    16321 tctttttgat ttattattta aaaacctgcc gcaaagatag gcaatcggct tataaaacaa
    16381 ggcaagaaag agggggacaa ttagaaaaaa gaacatctgt tattatcatt ctaataatta
    16441 acagattaag tagtaaatca aaacacaggg aagggggaca tttactgaaa taagaaacag
    16501 aaaagaagat gtgtcaaaag caactaaatt cccctccttc aggaaggagg agagtttagt
    16561 tacttttgac ttttgacaca tttacatttg cagtattaaa tatcacaaca aaatataagt
    16621 gtatatttga aaagtagagt tgcagtga
//
