LOCUS       gnlProkkaMCCBJNFP_10   12812 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCCBJNFP_10.
ACCESSION   gnlProkkaMCCBJNFP_10
VERSION     gnlProkkaMCCBJNFP_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 12:03:11
            Original ID  :: gnl|Prokka|MCCBJNFP_10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 25653
            Orig. end    :: 38465
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12812
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12810]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12810
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..12812
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12812
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             706..1365
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 180.3; E-value: 6.9e-55)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_30"
                     /transl_table=11
                     /translation="MARILVIDDQKDIVQLVVKALELQNHNVTGLTSVLDLDKNSLPRF
                     DLILLDIMMPDVDGLQFCHEIRNQVDCPILFITAKTQEADIVQGLSYGADDYICKPFGV
                     KELQARVAAHLRREHRERHHKLSLGEFQFDLSAQELYIENQLLDLTKSEYGICQFLAEN
                     KGQVFSKEQIYTHLYGYEDKGSPAAVAEHIKNIRAKLKEVGQNPIETVWGIGYKWH"
     CDS             1356..2750
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 126.7; E-value: 2.4e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_31"
                     /transl_table=11
                     /translation="MALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     LIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMPVNLQEESLL
                     NYQFKNAHGEKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTDLLEHFQKG
                     IAQVDAYVKELSELNKMSLKKTLTLEEVPVKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRHSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
     CDS             2851..4194
                     /locus_tag="ctg10_32"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
     CDS             complement(4459..5256)
                     /locus_tag="ctg10_33"
                     /transl_table=11
                     /translation="MNVADQKANGIDILTDGEFGRSMWHLDFVWGLKGIERYIAEHGYT
                     FKDHDGGQYETRKDIGIRVTEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHTYTE
                     LAIFDQLAVPGQVYETNEELKKGLINVYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPA
                     SFYSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSASEGTYEDIAK
                     KFLAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(5253..5408)
                     /locus_tag="ctg10_34"
                     /transl_table=11
                     /translation="MTKSKFQLVGSLLRPADLRKYKDEIEHRDDIQYPFYDALPGYQET
                     ETASIK"
     CDS             5561..5989
                     /locus_tag="ctg10_35"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             5991..6284
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 59.2;
                     E-value: 5.6e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_36"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDDSIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             6495..6836
                     /NRPS_PKS="Domain: PKS_KR (3-112). E-value: 4e-11. Score:
                     35.0. Matches aSDomain: nrpspksdomains_ctg10_37_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     111.9; E-value: 5.8e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_37"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLETITEEQFQRT
                     FNINVGGVI"
     aSDomain        6504..6830
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg10_37_PKS_KR.1"
                     /evalue="4.00E-11"
                     /label="ctg10_37_PKS_KR.1"
                     /locus_tag="ctg10_37"
                     /protein_end="112"
                     /protein_start="3"
                     /score="35.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLETITEEQFQRTFNI
                     NVGGV"
     CDS             7112..7258
                     /locus_tag="ctg10_38"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             7277..7432
                     /locus_tag="ctg10_39"
                     /transl_table=11
                     /translation="MALFFCLIKHNVSDNIVINNYVFKGGFPYQTSYTILLSTHFLVLF
                     YWELLY"
     CDS             7646..9478
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.4; E-value:
                     9.1e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_40"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDAIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             9481..9585
                     /locus_tag="ctg10_41"
                     /transl_table=11
                     /translation="MIVECDVLAILVKSYDKEDFKIYLLKVTYREWHH"
     CDS             10001..10858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_42"
                     /sec_met_domain="TIGR01716 (E-value: 9.4e-47, bitscore:
                     150.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCIAAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             10918..11718
                     /locus_tag="ctg10_43"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             11778..11927
                     /locus_tag="ctg10_44"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             12010..12810
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_45"
                     /sec_met_domain="Streptide_RRE (E-value: 6.6e-17, bitscore:
                     53.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.3e-22, bitscore: 71.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.4e-11, bitscore: 33.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLS"
ORIGIN
        1 tgtgattgag ggttttattc atacccataa ccggaagaaa tacttcctaa agatttattc
       61 tttagcaatt gtgatgggac tgattcaagt tggattctat aattttctac atcctctagt
      121 tagaccagat ggtttctttc cacaaaatat gatgctgtcg tcattcgcaa ttttgctcgt
      181 tgctcttcaa gggattgcat ggattcaaga aaagaaatac cttaaaggga taccaacttt
      241 actttttcca ttgttgcttc catggttaat gatgcctttt tatatgctaa gtgtgaacaa
      301 acctatgttt ggttttctac taaatttact caatttcaca gtattgccag tccatacatt
      361 tatcagtgat ggaggaacgt ggttgctttt gaccggtatc gctatgtatc tttgtcatag
      421 gaatcttatg aaagaagtgt ttgcttttat gagtgttagt ctcgtttggc tgctaatggc
      481 gattgtttta agtagacctt ctttttacga tttaatattc aaatactttg aatggatgga
      541 aatattttca gcacctttaa tgctttctta taatggtcaa agagggaaag ggtcaaaata
      601 tttgttctat gttttttacc caacccatat ttatctactt tacgccttgt cagttatctt
      661 ctatagatga tatgataagg ataactttga aggaaaggaa aggctatggc tcgaatactt
      721 gttattgatg atcaaaaaga tattgttcaa ttggttgtaa aggctttaga gctccaaaac
      781 cataatgtga cagggcttac aagtgtttta gatttggata agaactcttt acctcgattt
      841 gacctgattt tactggatat tatgatgcct gatgttgacg gtctacagtt ttgccatgag
      901 attcgaaatc aggtggattg cccaatcctc tttattacag ctaaaacgca agaagcagac
      961 attgtccaag ggttgagtta tggtgcggat gattacattt gcaaaccatt tggagttaaa
     1021 gaactccaag cgcgtgttgc agctcacttg agacgtgaac atcgtgagcg tcaccataag
     1081 ctttcacttg gggagtttca gtttgacttg tctgctcaag agctttatat tgagaatcag
     1141 ttgttagatt tgacaaagtc ggaatatggt atttgccagt ttttagctga aaataagggc
     1201 caagtctttt caaaagaaca aatctacacg catttgtacg gctatgagga taaaggcagt
     1261 ccggcagcag tggctgaaca tatcaagaat atccgtgcaa agcttaaaga agttgggcaa
     1321 aatcctattg aaacagtttg ggggattggt tacaagtggc actaataaaa aaacgagaac
     1381 actctctaag aacaatcttg ttatcttatg tcgtcagtct tacagttctc tctgtaatca
     1441 gcagtcttct tattttgtat ttgttcagct tgtcttttcg ttttggagtt ttgattccag
     1501 caaatcaagt tgagagtgat ttgtctgctg tgagaagtga tattgaaact tctaaggtct
     1561 ttaatcccga gattttacct gatggcacga gttatgtctt tttaactaga gattttaagc
     1621 ttaaaaagtc taacatgcct gttaacttgc aagaagaatc cttactaaat taccaattca
     1681 agaatgctca cggtgagaaa tacggctatt ttcagtcttt tgaacgatca gatggcatag
     1741 tcattgtcaa ttatcaacta tcacctcggt accgtaatga gtggatgaac caacattttc
     1801 ccaatgctga tcttatgatg attggttcaa tgtttgtatc tatcttaata atatttatta
     1861 ttttaacttt ttattatgca aataaattga gtcagcaact taaacctata ttaagggtta
     1921 ctgaaaaaat ttcccaacaa gatttggatt ttcaaacttc tcagtctaca attaaggaat
     1981 ttaatcaggt tttaagtggt ttggatcata tgcgtatagc acttcgtgag tctttgatgg
     2041 aaaattggaa ggcagagcaa gataaacaaa atcagatttc tgccctaaca catgacttaa
     2101 agacgcccct aacagttgct cgtggaaatg cggaactctt agctatgacg tccttggatg
     2161 aaaatcaaac ggacttgtta gagcattttc aaaaaggtat tgcacaggtt gatgcttatg
     2221 taaaagagtt gtcagaactc aacaaaatga gtttgaagaa gaccctgacg cttgaagaag
     2281 ttccagttaa ggaatttgtt gaagacattt acgatcaaac cttgtcatta gctcaaacga
     2341 aacaaatcaa tgtggtattt gacaagaagg aaattgcgaa agaaagcata ggcaattggg
     2401 ataagtcctt gttgaatcga gctattatga atattgtttc aaatgccgta gagcatacac
     2461 ccagtggcag tcagttgctc ctgaccgcta gggtagaaga agatgaattc aagtttatat
     2521 gccttgattc tggtcctgga ttttcccttg aatctcttga aaacgctact cagctatttt
     2581 atcaagagga taaaagcaga catagtcgca atcatagtgg ccttggtctg actattgcca
     2641 atgatattat tcgtttacac tatggtagtc tttctcttgc aaatgacaat ggcacgggtg
     2701 gtgctaaagt gactatcatt ttaccccttt taaatacaga tgactcctag tcgccagatg
     2761 aggagttttt tgctatacta ctaagagtaa aaatgaagaa agatttgtgg gagcaggatt
     2821 tcatcttgtt tccgaagagg tattagtgtc atgtctcaat caaaagcaga ttatattaac
     2881 gtgattggag ctggtttggc cggatccgag gcggcttatc agattgccaa acgtggtatt
     2941 ccagtaaaac tttatgaaat gcgtggggtc aaagcaacac cacagcataa gacaacaaat
     3001 tttgcagaat tggtttgctc taactctttc cgtggagata gcttgaccaa tgctgtaggg
     3061 cttctaaaag aagaaatgcg tcgtttggac tctatcatta tgcgtaatgg agaagctcac
     3121 cgtgtgccag caggtggtgc catggcggtg gaccgtgagg gctatgcaga agcagtgaca
     3181 gctgaaattg aaagtcatcc cttaattgaa gttatccgta aagaaatcac agaaattcct
     3241 gatgatgcta ttacagttat tgcttcaggt cccctaactt ctgatgcttt agctgaaaag
     3301 attcatgagc ttaacggtgg agacgggttc tatttctatg atgccgctgc accaatcgtt
     3361 gataaagcaa ctatcgacat gaacaaggtt taccttaagt cacgctatga taagggtgaa
     3421 gcagcttatc taaactgtcc aatgaccaag gaagagttca tggccttcta tgaggccttg
     3481 actacagctg aagaagctcc tttgaattct tttgaaaaag aaaagtattt cgaagggtgt
     3541 atgcctatcg aggttatggc taaacgtggt attaaaacaa tgctctacgg tcctatgaaa
     3601 ccagttggtt tggagtatcc tgaagattat atgggtccac gtgatggtga cttcaagaca
     3661 ccttatgcgg ttgttcagct tcgtcaggac aatgcggctg gtagcctcta caatatcgtt
     3721 ggtttccaaa cccacctcaa atggggagag caaaaacgtg tcttccaaat gattccaggt
     3781 cttgaaaatg cagaatttgt tcgttatggg gtaatgcacc gtaactctta catggattcg
     3841 ccaaacttgc ttaaacagac cttccaatca aaatcaaacc ctaatctgtt ctttgctgga
     3901 caaatgactg gtgttgaagg ttatgttgaa tcagctgcct caggtttggt tgctggaatc
     3961 aatgcagccc gtctctttaa gggtgaagat gaagttattt tccctcatac aacagcaatc
     4021 ggtagccttc catattatgt gacacatgct gaaagcaaac attttcaacc aatgaatgtt
     4081 aactttggta ttatcaaaga attagaaggc ccacgtattc gtgacaagaa agagcgttat
     4141 gaaaaaatcg cagaaagagc tcttaaggat ttgcaaactt ttatagatgc ttgatgctaa
     4201 cataaaaagc cctcacaaga gtgaaggctt ttcgttttag agaggagcga atagaaatat
     4261 cgattagcca aagaatttct tagcgatttc ttgaccttgt ttgattttag cccattgttg
     4321 aggtgttgcc agctcattac ctgagtcaca tgaggcgaaa ccacattggt gaaaggggaa
     4381 gagacgtttt tttggaagga tttgactcgc tttttcaagc aaatcgagaa cacgttcttc
     4441 gtcatctagg tcagtcgttt aagaagacaa tagcccaaat acaacttcag ctttactgtc
     4501 tttaagggct tccagagctt tgatatcacc agctgtatcg ctatcccatt caaggaagaa
     4561 gcggtcatag tgttgctctg ccaagaattt cttagcgatg tcttcgtaag ttccttcaga
     4621 agcagaacgg atttcataat taccacgaca gttgtgtgtc caaaccgtta aaccaagttc
     4681 gtgagtatag tcaacaacct cattattgat agcaacaaat tcatcggcca attctgccaa
     4741 atcaccattg ccgtctgagt agaaacttgc agggtttgat gggtcaaaaa gttcccagag
     4801 gcagtcatca aattgaacga ttttaccacc aacagccttg tattcatcta agaattcttt
     4861 atagacatta atcaaacctt ttttgagttc ttcgtttgtt tcatagactt gtccaggaac
     4921 agccaattga tcaaagatag caagttcagt gtaggtatga gcaggtcccc agatagtttg
     4981 tttggtatct tcatcaccag cttcagcctt aaccaatttg taaatatcta ggtagtggtg
     5041 gtttttacct gagagaggct cagtgacacg aataccgata tctttacgtg tttcatattg
     5101 accaccatca tggtctttaa aagtataacc atgctcagca atgtagcgtt caataccttt
     5161 gagtccccag acaaagtcca agtgccacat agaacgtcca aactccccat cggtaaggat
     5221 gtcaattccg ttagcttttt ggtcagccac attcacttaa tagatgcagt ttcagtttct
     5281 tgataaccag gaagggcatc atagaaagga tactggatgt cgtcacgatg ctcgatttcg
     5341 tccttgtatt tacggagatc cgcaggacga agaagagaac cgactaattg gaatttagat
     5401 tttgtcatta aatttacctc gaaatgtcta tttacatcta tattatctct tatgggaact
     5461 aatgaaaaat agttaatttc ttgctgtgga tatagtttta gactatacaa ggtttagctc
     5521 tgcaaaatga tacttcttat gataaaatgg aaagaaaacg atgaaggttg ggaatatgca
     5581 aaaaacattc tttattatta aaccagatgc tgttaaacgc catctaattg gtcaagtgct
     5641 tgatcgaatt gagcgacgtg gcttcgttat tgagcgtatg gagatgctga tgcttgacga
     5701 agaacgtctt aaagaacatt atgcccaatt ggctgataaa ccttttttcc ctagtatttc
     5761 tgaattcatg atgagtggtc cagcagttat tggtattatg tccggcccag gtgttattaa
     5821 gtcatggcgt gatatgatgg gagcaactaa tcctggggat gctgctcctg gaacgattcg
     5881 tggagacttt gcaacagcac cagatggtga catgattcca aatatcgttc atggctctga
     5941 ttcagaagaa tctgcggctc gagaaattaa gatttggttt ggtgagtagg atggatatag
     6001 cacagattca atcagaatta gctcaggatg gactattaat tgatgtcagg actccagaag
     6061 agtacgcaga aggtcatgtt aaggatgctt tattaatacc tcacacgcag tttttcacag
     6121 ctgacattcc agctaaaaaa gacgattcaa tttatcttta ttgtaaaatg ggatctcgtg
     6181 ctgaatttgc tgcaggtgta ctgaaagaac gaggatatac taaggttacc accttaggtg
     6241 gcctaggtga tatggaagca ctagggttta agtttgaaaa ataatacaca taaggtcact
     6301 agtggtgatc ttatttgctt tcaaaaagca tgacaaatta ttaacaacgc ttttataaag
     6361 gggtagaatc ttaattgagt taagacaaag cctatgaaaa tgactttgcc agaacttgat
     6421 taacttagca tattccaatt gagatagggc ttgtggttaa gcttgtgact acaattggta
     6481 gaggaggatt tcgtatgtca aaagttgcta ttgttacagg tgcaggtcaa ggtattggtt
     6541 ttgcgatttc aaaacgcttg gttgaagatg gttttaaagt cggggtattg gactatgacg
     6601 ctgaaactgc tgaaaaagca gttgttgagt tgtcagaaga caaggcattt tccgttgtag
     6661 cagatgtgtc taaacaagct gaggtagcag cagctttcca aaaagtagtt gatcactttg
     6721 gcgacttgaa tgttgttgtt aataatgctg gtgtgcacca acaaaacccc cttgaaacta
     6781 ttactgaaga acagtttcaa cgtacattta acattaatgt tggtggagtt atctgaggtg
     6841 cacaagctgc ccaagcacaa tttaaatcac ttggtcatgg tggtaaaatt atcaatgcaa
     6901 ctttacaagc aggtgttgta gggaactcta acttaactgt atatggtgga actaaattcg
     6961 tagttcgtgg tattactcaa actttggcgc gtgacttagc tgattcaggt ataactgtaa
     7021 atgcttacgc accaggtatc gttaagactc caatgatgtt tgacatttcc cacgaagttg
     7081 gtaaaatgct ggtaaagatg atgagtaggg tatgcaaact tttgctaaag atattaccct
     7141 caaacgtttg tcagaacctg aagatgttgc agcagcagtt agcttcctag ctggacctga
     7201 ctcaaactac atcacaggtc aaacaatcat cgttgatggt ggtatgcaat tccattaagg
     7261 ttaaaaggga gagcgaatgg ctctcttttt ttgcttgata aaacataatg tttctgataa
     7321 tatagttata aataattatg tttttaaagg tggattccca tatcagacat cttacactat
     7381 attgctgagc acccattttt tagtcttatt ctattgggaa ttattgtact agcctttggt
     7441 ttagctccat tttcaagtag ttcaatagag aacaagcgtt cagctattat taataagcac
     7501 tacaatgata attttaagaa ataagaagga ctaaatgcag tcataaagca gatattagag
     7561 ataggcaaat gcctgtcttt tttgtataat aggaggtgac ggttcgtttt ttaacaatca
     7621 caagtaagaa ttaggaaaga ataaaatgcc aaatattgaa gaattaaaac aaagacagga
     7681 gaagattcgc aacttctcga ttattgctca tattgaccat ggtaaatcaa cgcttgctga
     7741 ccgtatcttg gaaaagactg agactgtatc aagtcgtgag atgcaggcac aactccttga
     7801 tagtatggat cttgagcgcg aacgtggtat cactatcaaa ctgaatgcca ttgagcttaa
     7861 ctacaaagct aaagacggcg agacttatat tttccacctt atcgacacac cgggacatgt
     7921 ggactttact tatgaggtgt cacgttccct tgccgcctgt gagggtgcta tcttggtggt
     7981 agatgcagct caagggattg aagcacaaac acttgccaat gtttacttgg cacttgataa
     8041 tgacttggaa atcttaccag ttatcaataa aatcgacctt ccagcggcag atcctgagcg
     8101 tgtacgtaca gagattgaag atgttatcgg attagatgcc tcggaagctg tgcttgcatc
     8161 agctaaggct ggcattggta tcgaagagat tctcgaacaa attgttgaga aagttcctgc
     8221 gccccaaggt gatgtggaag cacctctcca agcccttatc tttgactctg tttatgatgc
     8281 gtatcgtggc gtcatactcc aagtgcgtgt ggttaacgga atggttaaaa cgggcgataa
     8341 gattcaaatg atgtctaatg gcaagacctt tgacgttact gaggttggta ttttcactcc
     8401 taaagctgtt ggccgtgact accttgcgac tggagatgtt ggttatgtag cagcttcaat
     8461 taagacagtt gcggatactc gtgtcggtga tacagtgaca cttgcggata atccagccgc
     8521 agaaccactt catggttata agcaaatgaa cccaatggtc tttgctggtc tttatccaat
     8581 tgagtcaaat aaatataacg acttgcgtga ggctcttgaa aagctccaat tgaatgatgc
     8641 cagtcttcaa tttgagcctg aaacgtctca agcccttggt tttggtttcc gttgtggttt
     8701 cttgggcctt cttcacatgg atgttatcca agagcgtttg gaacgtgagt ttaacatcga
     8761 tctcatcatg actgcaccat cagtagttta ccatgttaac actactgacg gtgaaatgct
     8821 tgaagtgtcc aacccatctg aatttccaga tcctacacgt attgatgcca ttgaagagcc
     8881 ttatgtcaaa gctcaaatta tggttcctca agagtatgtt ggtgctgtta tggagttggc
     8941 gcaacgtaaa cgtggtgatt ttgaaaccat ggaatatatt gatgataatc gtgttaacgt
     9001 tatctatcaa attccacttg ctgaaatcgt ctttgacttc tttgataaat tgaagtcatc
     9061 aactcgtggt tatgcaagtt ttgactatga attgtcagag taccgtcgtt cacaattggt
     9121 gaaaatggat attctcctta atggtgataa ggtcgatgcc cttagcttta ttgtccatag
     9181 agaatttgcc tacgaacgtg gaaaacttat cgttgataaa cttaagaaaa ttattccacg
     9241 tcaacaattt gaagttccta tccaagcggc tattggtcaa aaaattgttg cccgtacaga
     9301 tatcaaagct cttcgtaaaa acgtcttggc taaatgttac ggtggtgacg tttcacgtaa
     9361 acgtaaactc ctcgaaaaac aaaaagctgg taagaaacgt atgaaagcca ttggttcggt
     9421 ggaggtacca caagaagcct tcttgtctgt gctttcaatg gacgaagatg agaaataaga
     9481 atgatagtag aatgtgatgt tctggctatt ttagtaaaaa gttatgataa agaggatttt
     9541 aaaatttacc ttctcaaagt gacgtataga gaatggcacc actaatccaa catataaaac
     9601 attggaagaa attgccgctg caaccaatac tagattagtt gttgactttg ttccaataaa
     9661 gaactagttt ttgtatacac tcaaaaagct ctataatctc tatagtggtt ttacctacta
     9721 cagaaatcat agagtctttt ttatattata cccttattag agaacaacat cataccttaa
     9781 ctacaccaca aaagttagac atcgaaagtc taacttttgt ggtgtcttta ttttctattt
     9841 gtttagccaa cagcaattac aataatgctt tcaaaaatta gaagtaagat agctaaaaaa
     9901 ctttctttat tcatagaaat taacctccta tctcactata tgatataata cttttaagtt
     9961 tatctgggaa attctcgtat atgcaaaaga ggtgcttttt atgaaagatt atggaaaatt
    10021 atttaagaaa tttagagagt ctaggggatt agtcttaaaa gatatcgcaa agttaggcgt
    10081 atcagtatct catatttccc gctttgaacg tgaaaataca gatttgacaa ttagtaagtt
    10141 tatgtcagct ttaaatgcga taaatatgcc tattgatgag tttatgtatg cagcaaacga
    10201 ctttcagaga gatgagttta atgaaatctt agaaaagatt agtttatttg tttcagcaag
    10261 gaacgtgtca ggtatggaaa agttattaat ctctcaagta gaaaaaatcg aaaagcgtga
    10321 gactttttat actctaaata ctattttaat aaaaattcgt ttacaggact tatcagacaa
    10381 aagttactat gatgaatctg atatccaata tttatcagac tacctattct ctgtagaata
    10441 ttggggttgt tacgaactac tgttatttgc gaatactgta gatgtattga atcatcaaac
    10501 aatgatgctt ttatcaagag aaatgtgtaa acgttcagaa ttttacaagg atttaccaaa
    10561 ctaccgaagg ttacactcaa caatgctatt aaattgttat atcataagta ttgaaagaga
    10621 tgagtatatt gatgcgttgt attttgaaaa acagttaaat catagttgtt ttacggaaac
    10681 tgagatttac gagaaattag tgtttcatta ttcaaaaaat ttatatgaat taaagaagaa
    10741 taggagcaat aaagctattc tagaaatgaa gaagtgtatt gctgcaatga agctggctaa
    10801 tagtgagaat ttagctataa aatttgaaaa tcatttatct ggagtgttaa aaatgtagtt
    10861 ggatttgtgt atatggtata aattatcagt gtcaaaatta aatgatatat tattgatatg
    10921 agaattatta aatttcctga acagatttca gaagatatca ttcattatac gtttctagat
    10981 gatattatct cttataattg tgaaaagtgt agaggatctt gttgtcatgt gaataattct
    11041 ttattacttg atgcaaagac agcaagtttt ctaaaacgca cgtatcttaa agattttatt
    11101 gttagtgatg atagtgtttc attgttgagt tgtggtaaaa agtgctggtt tcattctgaa
    11161 ttgggttgta cgataaatga tttaggcttg aacaagccat taacttgtga attatatcct
    11221 tttcatatta agaaaattca gaacttctat attgtttctt ttactccttg tccgacattt
    11281 caactgaacc ttggtgaggg gcagaggtac aaggatatag aggatgtagt tttacgatat
    11341 attaaaactg gggtgccagt ttttagtccg tctttgcatg tttcagagga aaggctgaaa
    11401 tatgagattg agtatcaaaa caattttaaa aacactttat cagagtatta tcgaacaaag
    11461 actgccgatg gcactacaga gtttaaagaa tatgaaaaat ggtatatata ttatttagat
    11521 tttagatggg gaagtatacc cttatcttat acaagttcac aagcaaatca attttggaat
    11581 ctttacaaga gagtttgtga agatgtttat aaaaaaatat catatatacg aacagataac
    11641 atatacttta ttattgcaaa tcagtttaat aagacaattt caaagcattt tcagctaaat
    11701 tttatagata aagaatgatt tctatgattt gttatgggta cttattgatt cttaaataaa
    11761 taatggagga tattacgatg caagttagtg atgctattgc acaaattgaa ttagcagaag
    11821 aagaagttgt ttctagcggt ctatctattg acattatgga aattaaacct tctgttgcta
    11881 cagagttgat tgatggactc aaaggtcgtt gcccaccgtc tgtctaatag aactgattgt
    11941 aggattagag tctatctcta atcctttggt ttttatatta atatttttgg aagattgcag
    12001 ggaattaata tgacgagcaa tgtttactcg atttttttta attggtacaa taagcaagga
    12061 atactcagga ataataggaa taataaacta ttttcattaa atttagctac atttttagct
    12121 ttaaaattta tgtaccaatt ttcattgaaa aagttttctg attcaaagag tcaggtaata
    12181 aaaaatgtta tagattttct aaataacaat gaaatatcac tctctaagac caacactaaa
    12241 attgttgaat tttcaacgaa aataccatta aaagtgatac agattgaggt cacgaacaaa
    12301 tgtaacctaa gatgtatgca ttgttattta cctgattatt caaaggagct cgatagaaag
    12361 aaaatttcaa gtatagtata tgaagctaag cagctaggag taatggatgt tgatttcact
    12421 ggaggcgaac cattattatt acagggatta agtgaaatta tcgaggaagt attaaaagag
    12481 ggaatgtgta caacaatttt tacaaatgct gtatatattc ctgaagattt taaaatattg
    12541 attcaaagat atgatggtat aagactaaaa gttagtttag atggttggaa tgaaacaata
    12601 catgattcaa ttagaggaag aggtacattt aagagaacaa ttaagaatat tgaatatttt
    12661 aggagtttag gagtacctgt tactgttaat gttgttttga ataacaagaa tattagtgga
    12721 gtgaagtatt ttttggagtt gtttgatcga ttagatgtga aatatgcttt tgataggttt
    12781 ttaccttttg aaaggaataa tcgactatca at
//
