LOCUS       c00008_gnlPro..        15269 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FCOONGMP_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 13:55:17
            Original ID  :: gnl|Prokka|FCOONGMP_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15269
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15269
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2424:5269]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2425..5269
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15269
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15269
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             254..1624
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MTERKQGLWAKIRYIAASDRISGLIMLGFALAGLLLANLPFTAHA
                     FEELENFRIAIPYTNIDMGLGHWVQDGLLTVFFLTVGLELKQELATGSLSNPKAAAVPM
                     LCAVGGMMAPPVLFLLVLFLFSGFGSDPLAIASGTSFTFGEMSHGWAVPTATDIAFSLA
                     VLALFAKALPGSIRAFLMTLATVDDLLAIILIAVFFSSVNAWYWFVGIAVCAVVWYFLV
                     RMRKVPWLAVAIVGILAWVMMFEAGVHPTLAGVLVGLLTPAHERFGEKTPRAERYADKL
                     QPFSALLALPIFALFATGVHFESLTLALFISPVVVAVMVALVVGKPLGIMITAWLSTHV
                     AGLKMAKGLRVRDMFPAACACGIGFTVSFLISSLAYQDAELSAEARFGVLVGSIVAAVI
                     SGILLSRQSKKFELAAAASSKHKHHTADEDAAGEVESVLEDGTVVVSQMIDTHPKVK"
     CDS             complement(1749..2420)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MDRTSYTNLAKSWEYVEDHAFSRQSTDLNAIRTHAEEAGIPQGSA
                     AQAELLRMLVHMVNATSVIAVGTGSVVETLQLVNGLDNSGQLTAVDSSSQGIALIRTLF
                     NRLSDETQTTLRAVNAPVDVFLPRLNAENYDLIVVAGDAENYGASFEQAPRLLKKHGVI
                     VFTDILAFDSATSAGGVLNPANRDAKSIAMRGLLETVESDERFVTALTPTGTGLLVAVK
                     R"
     CDS             complement(2425..3354)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="Fer2_3 (E-value: 1.1e-43, bitscore: 143.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.7e-12, bitscore: 41.4,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00048, bitscore: 16.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGMENGVNTVTLRVNRFAPRAERARDRERGGSPFARKSSPFGDS
                     GTSARRRPRGKQWLQDYTLNVRPEDTVLDCLLKIKRTIDPTLAFRYSCGHGMCGSDAVS
                     INGTPTLLCTASVKDWAKPSNPTLVDDEGFRHTGDVSDIQENAVGAGDLGVIELAPLPG
                     FPVQRDLIADIDQMLNQIRKLKPYLQARGELATTADGKINAFEYLQNPQQLAKYELLSN
                     CIACGTCEGSCPVYAGGEAFIGPAALIAASRFINDSRDGQANARMDAIDSADGIAACQS
                     VRACTRECPRGIDVGEEIWQLIAQVKER"
     CDS             complement(3413..5269)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 338.3; E-value:
                     2.5e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-102,
                     bitscore: 338.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-27,
                     bitscore: 91.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPKHVEDMYDAVIVGAGAAGLSAALGMLRSEQMQALKEAGIEPN
                     ILVISKLQPLRSHTGSAEGGIAASLGNVEKDDWHWHYFDTVKGGDWLVDQDAAELLAKE
                     ASETVIDLEHDGVAFSRTEDGHIAQRRFGGHTKDFGKEPVRRAAYAADRIGHQILFSLW
                     QQCVAEGVEFAEEWYVTDLVITEDGSKVEGVVAFDTHKGQTHAIHARNVLLATGGAGRL
                     FHTTSNSWDLTGDGMALALQAGLQLEDSEFVQFHPTGLAHTGILLSEAARAEGGVLRNA
                     DGEAFMEKYAPGHADLAARDVVSRSIMAEIDAGHGVADPKDPEGPKDCVWLDMTGIDAD
                     HMHEVLPQVVETIEKYADLDPTHDFVPVKPTAHYTMGGIPITTDGEVYRWQNDERNVVE
                     GLFAAGECACVSVHGANRLGGNSLLDACLFGTRSGKALAERISSAPVNDPMAESDADNG
                     SDAVQQAADTRSNELKDLLVQLPEDEEHAADNPYQLMADLGTVMERAVAVRCDEQGIEQ
                     ALTALHDEFAPRAEALHAHSDSPTFNQEITAIWEVRHLLELGKAVLTSSDARHESRGSL
                     KRLDFPERDDEHFLAHSMVNASGQISWQPVHIVNMPPKAREY"
     CDS             complement(5422..6792)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MNENTTADTSVNATAIDDETLSRAVLTYCLDSADAMMYALVKGVG
                     SATHTLQLLADSGPGNHESVATAAYKTLDAALINGITRWGRTINARGMASFHGAMVSWQ
                     HRLTTLPSTDPEELKTWFTANGTQWIVAPHHPYWPSQLADLTIHTDWAAPLCLWGKGDP
                     QALVSCSEPVGVVGSRGVSEYGRQSAHELAKQAARAGHLIVSGGALGTDAAAHWGAIQA
                     MDEIGTPLAGRTVAVFAGGLNYIGPKSNERLFETIINHSGALISELCPGTVPEARRFLI
                     RNRLIAALSSTLIVAQARARSGALNTAGWANELNRRVFAVPGDVTMPHNTGCNRLIQEG
                     QASIICSLTDIDEFCHAAHRPQSADAADNDDEPSEESTDTSLSQPTNATAAILKAIRTC
                     SAKYGHVSTDGLLAILAESNPGEYSISRISMELGLMELNGLICTQHGNITITDASAT"
     CDS             complement(6789..8318)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MAIGSALSVGLIGLKAFIIQIQAFVSPGLPYFSIIGLPDTSLSEA
                     RERVKSACQASGAKWPETRVTVNLSPASMPKRGSSHDLAIAASVLSASGTIPHDCLNDT
                     VVLGEVNLDGTVLPINGLLPILLHARDQGVCKVIVPHANLDEAALVPDVDAIGIRHVGE
                     LIELMGGTANYTIPDMIRDVDANDGAMSVCPPPGDMNEVMGQETAKWALEVAAAGGHHL
                     MMTGPPGTGKTMLASRIPGIMSPLSESEQLEVASIRSLCGTLPSYGISDIPPFEAPHHT
                     ASTASLVGGGAGLAQPGAITRAHRGILFMDEAPEFSARTLQTLREPLESGYVAISRAKG
                     TTYYPARFQLIMAANPCPCGYAYGNGERCTCREKDRIKYFSRLSGPILDRIDIQIEVPP
                     VERINPGTVPSGESSHAIRLRVMVARQTAQERFREFGWVCNAQATGTWLRANTSTKAIE
                     LVNHALASERLSLRGADRAMRLAWTLSDLSGKTSPGPEEMMQGISMRTRLT"
     CDS             complement(8318..8770)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MNGNTTHNVPNATQRSEQLLDSIARRLHDGTLCARQVGELGEQYA
                     AAWLESQGWQTLDRNWHCRYGELDIVSRDDTGIIVFVEVKTRRTLRYGTPQEAVTSSKQ
                     INLRHAAVQWLSDSDHRTPHNGVRFDVVTVIVRDGKPLVHHIEGAF"
     CDS             complement(8943..9818)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MNDVILFDRDPRYIPRVAAVHDMCGYGKCSLTAAIPILSAAGCDV
                     CPVPTALFSAHTRYSVFTFHDTTEILDGYLDAWRKENVDLDGVYSGFLGSAEQVAIIKR
                     LYADYPHALRLVDPVMGDGGEIYATYTPELCEAMGTLVDGADVLMPNLTEASMLTGRTY
                     PGQNIDNAEVNGIIDALLALGAKNVVLKGVDRQDGIIRNYVASATSGASGKQEIAHDKL
                     PFMTHGTGDAFASALCGAVMAGRPLAESAHIAGEFVRHAMESTQFQPNHTERGVSFELD
                     LDELTRLVRR"
     CDS             10148..11461
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_9"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 7.9e-134,
                     bitscore: 441.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADSKNYRFETLQLHVGQEQADPATDSRAVPIYQTTSYVFHNFDH
                     AEARFGLADPGNIYGRLTNSTQGVFEDRIAALEGGAAGLAVASGAAAVEYAVRNITQSG
                     DHIVAAKNIYGGTFNLLRHTLPRDGITTTFVSAENPQEFEDAIQENTKLVYFETFGNPN
                     ADLPDFEAITAIAHKHHLPVIVDNTFATPYLFRPLEHGADVVVESATKFIGGHGTTLGG
                     VIVEGGNFNWAEVPGKFPTLTEPDPSYHGLNFYEALGGSAFVTRIRAILLRDTGATLSP
                     FSAFLLLQGTETLSLRVERHVENALKVIDYLKTVPEVESISHPSIEGRKDNELYKKYFP
                     NGGGSIFTFDIKGGKDAARVFIDNLHLFSLLANVADAKSLVIHPASTTHSQETPEELED
                     QGIHQGTIRLSIGTENIEDILDDLKGGFAALRESGLAK"
     CDS             11728..12279
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MAQEVKNDIKKALQVNTIPLIAIMTAVTTVLTMLVKIPTPIRGYL
                     NLSDTMIYFSAYAFGPWVGGIIGGLGPALSDLISGYPQWAIFTFVIDGLQAVLVGLLVK
                     KFNPANIIIGSVIAGVWKVFGYFIAGGILSGFGPALGEIAGNSFQMAVGLIVGFALFTA
                     VRQAYPPLVRLGNLGIKAGE"
     CDS             12403..14010
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MITVRDLGWKYAPLTDGSKPVESLKRVSFDIRSGSFVGIIGPTGA
                     GKSTLCMALAGIIPNLADGTMSGVVEVNGMNTSRHSVSALSERVGYVQQDPEAQLFCSS
                     VEDEIAFPLENRGVAPNIIDKQIDIMLDLVGMAGYRKRVPTSLSGGQMQRVAIAAALAA
                     EPDVLILDEPTAALDPEGKQEVFDVLDRIRQTRSMTVIMAEQDTEHIAYWADQVLFMVN
                     GEVVRNGDASLFTRERRLLESSGVRVSDGPSPVIKALPVGNDAKPKHAIISLDHVTHRY
                     GQGGNASPALDDVSLDIEQGAFVGLIGRNGSGKTTLAKHLNGLIQPTQGIVNVDGLDVS
                     KHSVGEMAAHVGFVFQNPDHQIFCSSTKEEIAFGPTALGLDAATVFKRVDEMMTLFDLH
                     RYEDVSPATLGYGERRAVALSSVIAMRTPILVLDEPTAGLDHRLASRFLGTVEKLNRHG
                     VTVIMISHDMRAVYRYCTHVLELEDGHIVQYGPIDKSQEAQQSPARQARQPYKSRGPVS
                     ATHVLLKIAKDECDKEER"
     CDS             14010..14828
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MDADLYVPGDGWLHRTDPRVKFLISIVMLALCLVWRNWAFILGIL
                     ILEHVMLATDRVPAERIGWVWKILAVLIVFIVVLWPVFDQSGTHVLWQWGWLRLTQENL
                     LMAAVMGLRIPALGFACFITLFTTSQTKLVRGLTSLGMPYKAGLTLATALRYIPVFFSI
                     FQSVSEAQRARGLDLSGKVNAAGKKRNIFVRLVDRFKSYLPIIIAVLIRAYKMSQSVGW
                     AMESRGLNLNRNGVKRTYRVNLTMSIADWIILVIAIAAAAGSVWLMTWLS"
ORIGIN
        1 gaatgcttat gtaaagcggc tgttgtcgag atacgttcgg tttctctccg agcgaacggt
       61 gtggtacaag aaaagcccgc catgccgaat aaaaccgtaa acaccagtga aaaagacggt
      121 ttggaaacat aaacgccgac acctctcggt acactggaac cgctattgaa gcgtctgcgc
      181 atgccaatac cgcagacgct tttcttaagt gaatggcggg ccgtggatac tcgcggcaac
      241 agacgggaga gcaatgaccg aacgtaagca gggactctgg gcgaaaatac gatacatagc
      301 cgcttccgac cgcatatctg gtctgattat gcttggcttc gccctcgcag gtctgttgct
      361 tgccaatctg ccgttcacgg cgcatgcgtt cgaagagttg gagaatttcc gcatcgccat
      421 tccctacacc aatatcgata tgggattggg acactgggtg caggatggtc tgctgacggt
      481 gttcttcctg actgtcggac tggaattgaa acaggaactc gccacaggtt cgctgtcgaa
      541 ccccaaggct gctgcagtgc cgatgctgtg cgctgtgggc ggtatgatgg ctcctccggt
      601 gttgttcctg ctggtattgt tcctgttctc cggtttcgga tccgatccgt tggccatcgc
      661 ttcgggaacg agtttcacct ttggtgagat gtctcatggt tgggcggttc ctacggccac
      721 tgatatcgcg ttctctttgg ctgtgcttgc tttgttcgcc aaagcgctgc cgggctctat
      781 tcgcgcgttc ctgatgacgc ttgccacagt ggacgatctg ctggccatta ttctgatcgc
      841 ggtgttcttc tcttcggtga acgcatggta ctggttcgtc ggcatcgccg tatgcgctgt
      901 cgtatggtat ttcctggtgc gtatgcgcaa agtgccatgg cttgccgtgg ccattgtcgg
      961 cattctggct tgggtgatga tgttcgaagc tggtgtgcat cctactttgg ctggcgtgct
     1021 tgttggattg ctcacgccgg ctcatgagcg tttcggagag aaaaccccac gcgccgaacg
     1081 ctatgcggac aagctgcagc cgttttccgc gttgctggct ctgccgattt tcgccttgtt
     1141 cgccactggt gtgcattttg aatcattgac gttggccctg ttcatttcgc cggtcgtcgt
     1201 tgccgttatg gtggctctgg tggtcggcaa gccgttgggc attatgatca cggcatggct
     1261 ttccacgcat gtggccggat tgaaaatggc taagggattg cgtgtgcgcg acatgttccc
     1321 cgcggcctgc gcatgtggca tcggctttac cgtatctttc ctgatttcct cgcttgcata
     1381 tcaggatgcc gaactgtctg ctgaagcacg tttcggtgtg ttggtcggtt ccatagtcgc
     1441 ggcggtgatt tccggcattc tgctgagccg ccaatccaag aagtttgagc ttgccgctgc
     1501 cgcatcctcg aagcataagc atcatactgc tgacgaggat gctgctgggg aagtggaatc
     1561 cgtgttggaa gacggcactg ttgtggtcag ccagatgatc gacacacatc caaaggtcaa
     1621 ataacgacgt tctggcgtat ggcattccgc gccatacgcc agacacaaca aaagccgaca
     1681 ctcatcactt atccgtgagt gtcggctttt tgtatgagga aacggtaggc cgctgggaac
     1741 ggcatgctct agcgcttgac ggccacgagc aaacctgtac ctgtcggggt gagggcagtg
     1801 acgaaacgct catcggattc cacggtttcc agcaaaccac gcatggcaat ggatttggcg
     1861 tcacgattgg cgggattcaa aacgccgcct gcggatgtgg ctgaatcaaa agcaagaata
     1921 tcggtgaaca cgattacgcc atgcttcttc aacaggcggg gagcctgctc gaaggaagcg
     1981 ccgtaatttt ccgcgtcacc ggcaactaca atcaaatcgt agttttctgc attcagacgt
     2041 ggcaaaaaca cgtcgacggg agcgttgacg gcgcgaagcg tggtctgtgt ctcgtcggaa
     2101 agccgattaa acaacgtacg aatcagcgca ataccctggg aagaggaatc aaccgccgta
     2161 agctgaccgg aattatccaa accgttgacc agctgcaacg tttccaccac ggaaccggtg
     2221 ccgacggcga tcaccgatgt cgcattcacc atatgcacga gcatgcgcaa cagctcggct
     2281 tgggctgctg aaccctgcgg aatgcctgct tcttcagcat gggtgcgaat agcattcaag
     2341 tcggttgact ggcgggagaa cgcatggtcc tcaacgtatt cccatgactt ggcgagattg
     2401 gtatatgacg ttctatccat gggttcagcg ttccttgact tgggcgatca gctgccagat
     2461 ttcctcgccg acgtcaatgc cacgcgggca ttcgcgggta catgcgcgga ccgactggca
     2521 tgcggcgatg ccatcggcgg aatcaatggc atccatgcgt gcgttcgcct gaccgtcgcg
     2581 ggaatcgttg atgaaacgag acgccgcgat aagggctgca ggtccgatga acgcttcgcc
     2641 gcccgcatac acagggcagc tgccttcgca agtgccacag gcgatgcagt tgctgagaag
     2701 ctcatacttg gcaagctgct ggggattctg cagatattcg aaagcgttga tcttgccgtc
     2761 cgcagtggtg gcgagttctc cacgcgcctg cagatagggc ttgagttttc tgatttggtt
     2821 gagcatctga tcgatatcgg caatcaaatc gcgctgcacc gggaaacccg gcaggggagc
     2881 gagctcgatg acgccaagat cccctgcgcc gaccgcattt tcctgaatgt cggaaacatc
     2941 tccggtgtgt cggaatcctt catcgtcgac caacgtcgga ttcgacggtt tggcccaatc
     3001 cttgacggac gcggtgcaca gcagggtggg ggtgccgttg atggacaccg catcggaacc
     3061 gcacatgcca tgtccgcacg aatagcggaa tgccagcgtc ggatcgatgg tgcgtttgat
     3121 cttcaacagg caatcaagca ccgtgtcttc cggacgcacg ttcaacgtgt aatcctgcaa
     3181 ccactgcttg ccgcgcgggc ggcggcgcgc cgacgtgccg gaatccccaa acggagagct
     3241 ttttctggcg aacggagagc cgccacgttc gcggtcgcgg gcacgctcgg cgcgcggggc
     3301 aaacctattc acccgcaatg tcaccgtatt cacgccgttt tccataccgc tcatgtaccc
     3361 gcctttccaa taaaaccgtc aactagtctg ccatacgccg tgcccagcgg aatcagtatt
     3421 cgcgggcttt tggcggcata ttcacaatgt gcaccggctg ccaggaaatc tggccggagg
     3481 cattcaccat ggaatgggcc aggaaatgct catcgtcgcg ttccggaaaa tcaagacgct
     3541 tcagcgagcc acgggattcg tgacgcgcat cggatgaggt gagtacggcc ttgccgagtt
     3601 ccagaaggtg gcggacctcc caaatggcgg tgatctcctg gttgaacgtg ggggagtcgg
     3661 aatgcgcgtg cagggcttcg gcacggggcg caaactcatc atgcaatgcc gttagcgcct
     3721 gttcgatacc ctgctcgtcg caacgcacgg cgacagcgcg ttccatgacg gtacccagat
     3781 cggccatcag ctggtaagga ttgtcggctg catgctcctc gtcttccgga agctgcacca
     3841 gcagatcctt gagttcgttg gaacgggtgt cagcggcctg ctggaccgca tccgaaccat
     3901 tgtcggcgtc ggattcagcc atgggatcgt tcactggagc gctggaaatg cgttccgcca
     3961 gcgccttgcc ggagcgggtg ccgaacaggc atgcatccag cagggaattg ccgccgagac
     4021 ggtttgcgcc gtgcacggac acgcatgcgc attcgccggc agcgaacagg ccttcgacga
     4081 catttcgttc gtcgttctgc caacggtaga cttcgccgtc ggtggtgatc ggaatgccac
     4141 ccatggtgta atgcgcggta ggcttaaccg gcacgaaatc gtgtgtcgga tcaagatccg
     4201 catatttttc gatggtttcc accacctgcg gcagtacctc atgcatatgg tcggcatcaa
     4261 taccggtcat atcaagccac acgcaatcct ttggcccttc ggggtccttc ggatccgcca
     4321 cgccgtggcc ggcatcgatt tcagccataa tggaacggct caccacatct cgtgcagcca
     4381 aatcggcatg gccgggagca tacttttcca tgaatgcctc gccatcggca ttgcgaagca
     4441 cgccgccttc cgctcgtgcc gcttcagaca gcagaatgcc ggtatgcgcc agaccagtcg
     4501 ggtggaattg cacgaattcg ctgtcttcaa gctgcagtcc cgcttgcagt gcgagagcca
     4561 tgccgtcgcc ggtcagatcc catgaattgg aggtggtgtg gaataggcgg cctgcgcctc
     4621 cggtggccag aagcacgttg cgtgcgtgga tggcgtgcgt ttggccctta tgcgtgtcaa
     4681 atgccactac gccttcgact ttggatccgt cttcggtgat taccagatcg gtcacgtacc
     4741 attcctcggc gaattccacg ccttcggcca cgcattgctg ccacaaggag aagaggatct
     4801 gatggccgat gcggtcggcc gcataggcgg cgcggcgaac cggttccttg ccgaaatcct
     4861 tggtatgtcc gccaaaacgt cgttgtgcga tatggccgtc ctcagtacgg gagaacgcca
     4921 caccgtcatg ttccagatcg attacggttt ccgacgcctc tttggcgagc agttcggccg
     4981 cgtcctggtc gacgagccaa tcgccgcctt tgaccgtgtc gaagtagtgc cagtgccagt
     5041 cgtctttttc gacgttgccg aggctggccg caatgccgcc ttccgcggaa ccggtgtgcg
     5101 agcgcaacgg ctggagtttg gagatcacca ggatgttcgg ctcgatgccg gcttccttca
     5161 gggcttgcat ttgttcgctt cgcagcattc ccaatgctgc ggacaggcct gccgcgcctg
     5221 cgccgacgat tactgcatca tacatatctt caacatgctt cggactcata gcaacgattt
     5281 tcgcacaagg tgtgacctca ttgcggtttg ccggttggcg ggtttgccgc tgcatgcgtg
     5341 attatgcgtg tctgatgcgt atgttttcga tggattccgt tgatctgtgc aggcttggcg
     5401 gtggcgttgt tgggcgtgat gtcatgtggc gcttgcgtcg gtgatggtga tgttgccatg
     5461 ctgtgtgcag ataagtccgt tgagttccat taatcccagc tccatgctga ttcgtgagat
     5521 tgagtattct ccgggattgc tttcggccag gatggcgagt agaccgtcag tggagacgtg
     5581 gccgtatttc gcgctgcatg ttcgtatggc tttgagtatg gctgcagtgg cgttggttgg
     5641 ttgcgacaga ctggtgtcgg ttgactcttc cgacggttcg tcgtcgttgt ctgccgcgtc
     5701 ggctgattgc gggcgatgcg ctgcgtggca gaattcgtcg atatcggtca gcgagcagat
     5761 gatggaggct tggccttctt gtatgagtcg gttgcatcct gtgttgtgag gcatggttac
     5821 atctcctggc acggcgaata cacggcggtt gagttcgttg gcccatcctg cggtgttaag
     5881 cgcgccggag cgtgcgcgtg cctgggctac gatgagggtg gatgatagcg ccgctatcag
     5941 gcggttcctg ataaggaatc gtctggcttc cggaacggtt ccggggcaga gttccgagat
     6001 gagcgcgccg gaatggttga tgatggtttc gaagaggcgc tcgttgcttt tcggaccgat
     6061 atagttgagt cctccggcga ataccgcgac ggtgcgtcct gcgaggggcg ttccgatctc
     6121 gtccatggct tggatggctc cccagtgggc ggccgcatcg gtgcccagag cgcctcctga
     6181 cactatgaga tggcctgctc gggccgcttg tttggcgagc tcgtgtgcgc tttgccttcc
     6241 gtactcgctt acgccgcgtg atccgacgac accgaccggt tcggagcatg acaccaacgc
     6301 ttgggggtca cctttccccc ataggcataa tggcgcggcc cagtccgtgt gtatggtgag
     6361 gtcggcaagc tgcgaaggcc agtaggggtg atgcggcgcg acgatccact gcgtgccgtt
     6421 tgcggtgaac cacgttttga gctcctcggg gtcggtgctg ggcaatgtgg tcaggcgatg
     6481 ctgccacgag accattgcgc cgtggaagga ggccatacct cgagcattga tggtgcgtcc
     6541 ccaacgtgta atgccgttga tgagcgccgc gtccaaggtt ttataggctg ccgtggccac
     6601 gctttcatga ttgcccggac cgctgtcggc aagcagttgc aaggtatgcg tggctgatcc
     6661 gacgcctttg accagcgcgt acatcatcgc atcggcgctg tccagacaat aggtgagcac
     6721 cgcgcgtgac agggtctcat cgtcgatggc ggttgcgttg acgctcgtat cggcggttgt
     6781 gttctcgttc atgtcaacct cgttctcatg gagattcctt gcatcatctc ttccggtccg
     6841 ggagaggttt tgcctgacag gtcggatagc gtccatgcga gtcgcatggc tcggtccgcc
     6901 cctctgaggc tgagccgttc gctggccaac gcatggttca cgagctcgat ggcttttgtg
     6961 gacgtgttgg cgcgaagcca tgttccggtg gcttgcgcat tgcagaccca tccgaattcc
     7021 cggaaacgtt cctgtgccgt ttgccttgcc accatgaccc gcaggcggat ggcgtggctg
     7081 gattcgccgg aaggaaccgt gcctgggttg atgcgttcca caggaggcac ttcgatctga
     7141 atgtcgatgc ggtcgaggat cggccccgac aggcggctga agtacttgat acggtctttt
     7201 tccctgcacg tgcagcgctc gccgttgccg tatgcgtagc cgcaggggca aggattggcc
     7261 gccatgatca gttggaatcg tgccggatag taggtggtgc ctttcgcgcg ggatatcgcc
     7321 acatacccgg attccaatgg ttcgcgcaag gtttgcaggg tgcgtgccga gaattcgggc
     7381 gcctcgtcca tgaataggat gccccgatgc gcccgcgtga tcgcgcctgg ttgagccaat
     7441 cccgcgccgc cgccgaccaa ggatgcggtg gatgcggtat ggtgcggcgc ttcgaatggc
     7501 ggaatatcgc tgatgccata gctgggcaat gtgccgcata gggagcggat cgaggcgact
     7561 tccagttgtt ccgattcgct gagcggactc ataatgccgg gaatgcgcga ggcgagcatg
     7621 gtttttccgg tgccgggagg accggtcatc atcagatgat ggccgccggc agccgccact
     7681 tccaacgccc atttggccgt ttcctgcccc atgacttcgt tcatatctcc gggaggagga
     7741 cataccgaca tggcgccgtc gttggcatcc acgtctcgga tcatatcggg tatcgtatag
     7801 ttcgcggtgc ctcccatcag ttcgatcagt tcgccgacgt gacgtattcc aatggcgtcg
     7861 acgtcgggca caagggccgc ctcgtccaaa ttggcatgcg gtacgatcac cttgcatacg
     7921 ccttgatcgc gtgcatgcag cagaatcggc agcagaccgt tgatgggcag taccgtgcca
     7981 tcgagattca cctctccgag cacgacggtg tcgttcaagc agtcatgcgg tatcgttccg
     8041 gatgcgctaa gcacgctcgc tgcgatcgcc agatcgtgtg aggatccgcg tttgggcatg
     8101 gacgccggcg aaagattgac cgtaacccgt gtttccggcc atttggcacc gctggcctga
     8161 catgcggatt tgacacgttc cctcgcttcg gagagcgagg tgtcgggaag tccgatgatg
     8221 gaaaagtagg ggagtcccgg agatacgaac gcctggattt ggatgatgaa ggctttcagg
     8281 ccgatgagac ccacggaaag cgcgctgccg atagccatca gaacgctcct tcgatatggt
     8341 ggacaagcgg tttgccatca cggacgatga cggtgacgac gtcgaagcgc acgccgttat
     8401 gcggcgtgcg atggtcgctg tccgacagcc attgcacggc cgcgtggcgc aggttgatct
     8461 gcttggatga cgtcacggct tcctgcggag tgccatagcg gagcgtccgc ctggttttga
     8521 cttcgacgaa gacgatgatt cccgtatcgt cgcgtgaaac gatatcgagt tcgccatatc
     8581 ggcagtgcca gttgcggtcg agcgtctgcc agccttggct ttccagccat gcggccgcat
     8641 actgttcgcc gagttcgccg acctgtcgtg cgcacagtgt gccatcatgc agtcgccgtg
     8701 cgatggaatc aagaagctgt tccgagcgct gcgttgcgtt cggaacgtta tgtgttgtgt
     8761 tgccgttcat gattcaagtc cagcagaaag gaccggcgcg aagcaagggc gaacggcgaa
     8821 tgtggataga ggatgcggtt tcgggcgtgt ttgggatagt tggtggataa cttgccgtta
     8881 tccacattgc tccacaaggc gagcggccat ggaacgcccg aaaccgcata tggttggaat
     8941 gttcagcggc gaaccagacg cgtcaactcg tcaaggtcca gctcgaagct cacaccgcgc
     9001 tcagtgtggt tcggctggaa ttgcgtgctt tccatggcat ggcgtacgaa ttcgccggcg
     9061 atatgcgccg attcagccag aggtctgccg gccatcaccg caccgcataa tgcggatgcg
     9121 aaggcgtcgc cggtgccatg tgtcatgaac ggcagcttgt cgtgcgcaat ctcttgcttg
     9181 ccggatgcgc cggaagtggc cgatgccaca tagttgcgaa tgatgccatc ctgacggtca
     9241 acgcctttga gcaccacgtt tttcgctccc aaggcaagca gcgcgtcaat aatgccgttc
     9301 acttccgcgt tgtcgatgtt ctgccccggg taggtgcgtc ccgtcagcat ggacgcttcc
     9361 gtcaaattcg gcatcagcac gtcggcgcca tccaccagcg tgcccatcgc ctcgcataat
     9421 tccggcgtgt atgtggcgta gatctcgccg ccgtctccca tcaccggatc caccaaacgc
     9481 aaggcgtgcg ggtaatccgc atacagacgt ttgataatcg cgacttgttc ggcggaaccg
     9541 aggaaaccgg aatacacgcc gtccaaatcg acgttctcct tgcgccacgc atccagatag
     9601 ccgtccaaaa tttcggtcgt atcgtggaac gtgaacacgc tgtagcgcgt atgcgccgaa
     9661 aacagcgccg tcggcacggg gcatacgtcg catccggccg ccgacagaat cggaatggcc
     9721 gccgtcagcg agcacttgcc gtaaccgcac atgtcgtgca ccgcggccac acgtggaatg
     9781 taccgtgggt cacggtcgaa cagaatcaca tcattcatgg gaaccctctc ttgcgattgc
     9841 ctgaccatga ctttagccgc ttgcctgact tcaccgcccc atcgcctcgt acggcgagtc
     9901 accatgatgc cgtttgctgg cgtgtcgcaa gttttttgat ggctaccaga gtagttttgc
     9961 aaagcctgga tggcaatgat tgcaacggtt tataagggga tataggcaag tgcgataacg
    10021 ctcggtttgc attgcgaagc gacgtcggat tattgtcgct accaacacct gaccgaccgc
    10081 cacacacggc aaggcgggtg gtcagcaaga caagcaacga accacttccc cacaaggagc
    10141 agaaaccatg gcagattcca agaactaccg cttcgaaacc ctgcagcttc acgtcggcca
    10201 ggagcaggcc gacccggcaa ccgattcccg cgcggtgccg atctaccaga ccaccagcta
    10261 cgtgttccat aactttgatc acgccgaggc gcgttttggt ctggccgatc cgggcaacat
    10321 ctacggccgc ctgaccaatt ccacccaggg cgtgttcgaa gaccgcatcg cagcccttga
    10381 aggtggcgcc gctggtttgg cagtcgcttc cggcgccgcc gcggtcgaat acgccgtgcg
    10441 caacatcacc cagtccggcg accacatcgt ggctgccaag aacatctacg gcggcacctt
    10501 caacctgctg cgccacaccc tgccgcgtga cggcatcacc accaccttcg tctccgctga
    10561 gaacccgcag gagttcgagg atgccatcca ggagaacacc aagctcgtct acttcgagac
    10621 cttcggcaac ccgaacgccg acctgccgga tttcgaagcc atcaccgcca tcgcacacaa
    10681 gcatcatctg ccggtgatcg tcgacaacac tttcgccacc ccgtacctgt tccgcccgct
    10741 ggagcacggt gctgacgtcg tggtcgaatc cgccaccaag ttcatcggtg gccacggcac
    10801 caccctcggc ggcgtgatcg tggaaggcgg caacttcaac tgggccgaag tgccgggcaa
    10861 gttcccgacc ctgaccgagc cggatccgtc gtaccacggt ctgaacttct acgaggctct
    10921 gggcggttcc gcgttcgtga cccgcatccg cgccatcctg ctgcgcgaca ccggcgcaac
    10981 cctgtctccg ttctcggcct tcttgctgct gcagggcacc gaaaccctgt cgcttcgcgt
    11041 cgagcgccat gtcgagaacg cgctgaaggt catcgactac ctgaagaccg ttccggaagt
    11101 cgaatccatc tcccacccgt ccatcgaagg ccgcaaggac aacgagctgt acaagaagta
    11161 cttcccgaac ggcggcggct ccatcttcac cttcgacatc aagggcggca aggacgcggc
    11221 acgcgtgttc atcgacaacc tgcacctgtt cagcctgttg gccaacgtgg ccgacgccaa
    11281 gagcctcgtg atccacccgg cctccaccac gcactctcag gagacgccgg aggagcttga
    11341 ggaccagggc atccaccagg gcacgatccg tctgtccatc ggcaccgaga acatcgaaga
    11401 catcctcgac gatctcaagg gcggtttcgc ggctctgcgc gaatccggtc tcgccaagtg
    11461 aggcgtatcg gatcggcgga ataacgccat cctgagcaaa tgaaacggtt tgtggcaccg
    11521 aagagaaggt tggtgccaca aaccgtttcg ccatattcgc ggacgttgtc atcgtaatgt
    11581 agcgcagatg gtatagaatc tgcgattgtt acgaaaagta atatctaaat tctatctttt
    11641 gaaagaaaga agttcagatt tctttcaaaa agataaatag tggtaatgat attgcggatt
    11701 acgtaaagag agaagagaga ggcgattatg gctcaagaag tcaagaacga tatcaaaaag
    11761 gcgttgcagg tcaacaccat tccgctgatc gccattatga ccgcggtcac cacggtgctg
    11821 accatgctcg tgaagatccc gaccccgatc cgtggctacc tcaacctgtc cgacaccatg
    11881 atctatttca gcgcgtatgc gttcggacca tgggtgggcg gcattatcgg cggtcttggc
    11941 ccggcgttga gcgatctgat ttccggttat ccgcagtggg ccatcttcac gttcgtcatc
    12001 gatggcctgc aggctgtgct cgtgggcctg ctcgtcaaga agttcaatcc ggcgaacatc
    12061 atcatcggtt cggtgatcgc aggcgtatgg aaggtgttcg gctatttcat cgcaggcgga
    12121 atcctttccg gatttggccc ggcgttgggt gagatcgcgg gcaactcctt ccagatggcg
    12181 gtgggtctga ttgtgggctt cgcgctgttc accgccgttc gtcaggccta tccgccgctg
    12241 gtacgtttgg gcaacctcgg tattaaggcg ggggagtgat acattaatat catgtgaagg
    12301 caggcccgtg gatttgccga tgaaaggcga ttccacgggt tttattgtga aatgcggtta
    12361 ccggctgcgg aaaaaaatgc gtgaaagcac ggggtgagcg tcatgattac ggttcgcgac
    12421 ttaggatgga agtacgcgcc actgaccgac gggagcaagc cggtggaaag tctcaagcgc
    12481 gtcagcttcg acatccggtc cggatccttc gtcggcatca tcggaccgac cggagcgggc
    12541 aagtccacgc tatgcatggc attggccggc atcattccga acctggccga cggcaccatg
    12601 agtggcgtcg tggaagttaa cggcatgaat acgagcaggc actccgtctc ggcactgtcg
    12661 gagcgcgtcg gctacgtgca acaggatccg gaagcgcagc tgttctgctc gagtgtcgag
    12721 gatgagatcg ctttcccgct ggaaaaccgc ggagtagccc caaacatcat cgacaagcag
    12781 atcgacatca tgctcgactt agtcggcatg gccggatacc gcaagcgtgt gccgaccagc
    12841 ctgtcgggag gccagatgca gcgcgtggcc atcgccgccg cgctcgcggc ggaacccgat
    12901 gtgcttattc ttgacgaacc caccgcggcc ctcgaccccg aaggcaagca ggaagtgttc
    12961 gacgtgctcg accgcattcg ccagacccgt tccatgacgg tgatcatggc cgagcaggat
    13021 accgaacaca tcgcctactg ggccgatcag gtgctcttca tggtcaacgg tgaagtggtg
    13081 cgcaatggag acgccagcct atttacccgg gaacgtagac tgttggaatc ctccggcgtg
    13141 cgggtgagtg acggaccatc tcccgtcatc aaggcgttgc cggtagggaa cgacgccaag
    13201 ccgaagcatg cgatcatcag tctggaccat gtgacgcacc gctatgggca gggcggcaat
    13261 gcgtctcccg cactggacga cgtcagcttg gatatcgaac agggcgcctt cgtagggctt
    13321 attgggcgca acgggtcagg caaaaccacg ctcgccaagc atctgaacgg gctgattcaa
    13381 cccacgcaag gaatcgtgaa tgtggatggg ctcgacgtgt cgaagcatag cgtgggcgaa
    13441 atggccgcgc acgtcggatt cgtattccaa aatcccgacc atcagatttt ctgctccagc
    13501 accaaagagg agatcgcgtt cggcccgacc gcgctcggac ttgacgcggc caccgtgttc
    13561 aaacgtgtcg acgaaatgat gacattgttc gacctgcacc ggtatgagga tgtttcgccg
    13621 gccacgctcg gctacggcga acgacgtgcg gtggcattgt cttcggtgat cgccatgcgt
    13681 acgccaatac tcgtcctcga cgaacctacg gcgggtctcg accatcgtct cgcatcacga
    13741 ttccttggaa ccgtggaaaa actcaaccgg catggcgtca ccgtcatcat gatcagccat
    13801 gacatgcgtg ccgtatatcg gtattgcacg cacgtgctcg aattggaaga cggtcatatc
    13861 gtgcaatatg gaccgatcga caaatcgcag gaagcgcaac aatcgcccgc gcgacaggcg
    13921 cggcagccgt acaagtcgcg cggtccggta tcggcgaccc acgtattgtt gaaaatcgcc
    13981 aaggatgaat gcgacaagga ggaacgctga tggatgccga cctgtatgtg ccaggcgacg
    14041 gatggttgca tcgcaccgat ccgcgcgtca aattcctcat ctccatcgtc atgctggccc
    14101 tttgcctcgt atggcgtaac tgggcgttca tcctcggcat cctcattctc gaacatgtga
    14161 tgctcgccac cgaccgtgtg cccgccgaac gcattggatg ggtgtggaag atcctcgccg
    14221 tgctcatcgt gttcatcgtg gtgctttggc cggtcttcga ccagagtgga acgcacgtgc
    14281 tctggcagtg gggatggttg cgtctcacgc aggagaacct gctcatggcg gcggtgatgg
    14341 gtctgcgcat tccagcgctc ggctttgcat gtttcatcac gctgttcacc accagccaga
    14401 ccaaactggt tcgtggcctt acctcgcttg gtatgcccta caaggccggg cttaccctgg
    14461 caaccgcatt acggtatatt cccgtgttct tttccatctt ccaatccgtg tccgaagcgc
    14521 agcgtgcgcg agggcttgat ctgagcggca aagtcaatgc ggcaggtaaa aaacgcaaca
    14581 tattcgtacg tctcgtagac cggttcaaat cgtatctgcc gatcatcatc gccgtattga
    14641 tccgcgccta caaaatgagc caaagcgtgg gctgggccat ggaatcgcgc ggactcaacc
    14701 tgaatcggaa cggtgtgaaa cgcacatatc gggtcaatct cacgatgagc attgccgact
    14761 ggattattct cgtgattgcc atcgccgccg ccgcaggcag cgtgtggttg atgacatggc
    14821 tgtcataggg ggtgcaatga cacaggatga agggcgtacc acaatcaccg cacgtgattt
    14881 gaaggtggta tcggcactgc aatgcaacgg acgcatgacc atgcaggcgc ttgccgataa
    14941 aatcggcatt tccgtatatg cggcgacgga aagctacaaa cggctcaccg atgcgggcat
    15001 catgaccatt gtgcccgtat gcaatccgtt gagtctcggc aattacagtc aggtgcttgt
    15061 gggactgcgc atcaacggca atcgcaacga ggcgctcgcc atgctcaaag ccatgcctca
    15121 ggtcacctat gtggtctgca cgctgggcga tgccgacatc atcgccgaag ccgtggtgta
    15181 ttcagccgac ggtatggacc atttcctgaa gtacgatttg cgcgcactgc ccggattgac
    15241 ccgtctgcaa gtgttctcct gcggtcgat
//
