LOCUS       gnlProkkaMMDJCEPO_5    13562 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMDJCEPO_5.
ACCESSION   gnlProkkaMMDJCEPO_5
VERSION     gnlProkkaMMDJCEPO_5
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 03:50:07
            Original ID  :: gnl|Prokka|MMDJCEPO_5
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 141370
            Orig. end    :: 154932
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13562
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8562]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8562
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13562
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13562
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             342..2831
                     /locus_tag="ctg5_152"
                     /transl_table=11
                     /translation="MSLAPDKLHTLIASGDVYIRSEKPLQSIPEADVVCYGLWVDPSLA
                     THHGVFASDRKHPEQLDFMLQKPSLAELESLSKTHLFLMDIGIWLLSDRAVEILMKRSH
                     KESSEELKYYDLYSDFGLALGTHPRIEDEEVNTLSVAILPLPGGEFYHYGTSKELISST
                     LSVQNKVYDQRRIMHRKVKPNPAMFVQNAVVRIPLCAENADLWIENSHIGPKWKIASRH
                     IITGVPENDWSLAVPAGVCVDVVPMGDKGFVARPYGLNDVFKGDLRDSKTTLTGIPFGE
                     WMSKRGLSYTDLKGRTDDLQAASVFPMVNSVEELGLVLRWMLSEPELEEGKNIWLRSEH
                     FSADEISAGANLKRLYAQREEFRKGNWKALAVNHEKSVFYQLDLADAAEDFVRLGLDMP
                     ELLPEDALQMSRIHNRMLRARILKLDGKDYRPEEQAAFDLLRDGLLDGISNRKSTPKLD
                     VYSDQIVWGRSPVRIDMAGGWTDTPPYSLYSGGNVVNLAIELNGQPPLQVYVKPCKDFH
                     IVLRSIDMGAMEIVSTFDELQDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLK
                     DFGAGIEVTLLAAIPAGSGLGTSSILASTVLGAINDFCGLAWDKNEICQRTLVLEQLLT
                     TGGGWQDQYGGVLQGVKLLQTEAGFAQSPLVRWLPDHLFTHPEYKDCHLLYYTGITRTA
                     KGILAEIVSSMFLNSSLHLNLLSEMKAHALDMNEAIQRGSFVEFGRLVGKTWEQNKALD
                     SGTNPPAVEAIIDLIKDYTLGYKLPGAGGGGYLYMVAKDPQAAVRIRKILTENAPNPRA
                     RFVEMTLSDKGFQVSRS"
     CDS             3971..4489
                     /locus_tag="ctg5_153"
                     /transl_table=11
                     /translation="MSQQQEYWFAARTRKDQELTTRDALEKIGVEYFLPTQFVIRQLKY
                     RRRRVEVPVIRNLIFVHATKEFACAIANEYGVRLFYMRDFDTKSMLIVPDKQMKDFMFV
                     MNLDPAAVILNDDCFAVGTKVQVIKGDFCGVEGELASLSNRTYVTIRIRGVLSASVKVP
                     KSYLRILAP"
     CDS             4525..4998
                     /locus_tag="ctg5_154"
                     /transl_table=11
                     /translation="MTQIHELQHVAHELLYLGADGSPIYTDSFRQLNTEVLQKSDALFA
                     LKGENPEEEARLCLALLMGYNATIYDYGDKESKKQVILDRSLLVLESLPSSLLKCQLLT
                     YCYGEVFEEELAKEAHAIIDGWKDRELLEEEREIVENLRILEEPPYLFSNKSC"
     CDS             5001..6302
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 200.2;
                     E-value: 7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_155"
                     /sec_met_domain="CTP_transf_like (E-value: 3.5e-15,
                     bitscore: 50.2, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 6e-118, bitscore:
                     386.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.7e-63, bitscore:
                     207.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVYVGMSADIIHPGHLNIIHEAQKLGNVTVGVLTDAAIASYK
                     RLPYLTYEQRSLIVQNLKGVDEVIPQTTLDYIPNLELLKPDFVVHGDDWKEGVQKETRQ
                     RVIETLSKWGGQVIDIPYTQGISSTKLNSKLKEIGTTPEVRLKRLKRLIEAKSIVRICE
                     SHSGLTGLIIENTSVEVNGMKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDAL
                     ECTTKPVIFDGDTGGKIEHFVFTVRTLERLGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCDKISAGKRAQITDDFMIIARIESFIAGKGLDDAMKRALAYIEAGADGIMIHSKD
                     KSGEDIRLFCKALREVNQSIPIVVVPTTYNHITDEELSTWGINVVIYANHMLRSAYPAM
                     LNTAKSILLHARSYEANDLCMPVKDILELIPGTK"
     CDS             6310..7377
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 68.6;
                     E-value: 7.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_156"
                     /sec_met_domain="TPP_enzyme_N (E-value: 8.9e-18, bitscore:
                     58.2, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.9e-21, bitscore:
                     67.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISPELFINSLVQNELNFFTGVPDSLLKHICAYITDHIASNSHIV
                     AANEGAAIGLAVGYHLATNKIPVVYMQNSGIGNSINPLLSLVDKEVYNIPLLLLVGWRG
                     EPGVKDEPQHIKQGKVTIPLFDSMRIKNQILSKDKSDFLQQLNVALEYIRETNEPFVFI
                     IQKETFSDYKLQTPNNNALLLDRETAIKIIVSSISKNDIVVSTTGMISRELFEYRDNMG
                     ESHEKDFLTVGSMGHASQIALGIALQKKARTVYCFDGDGAVLMHMGGLTTIGSIKPSNY
                     IHVLFNNGAHDSVGGQPTVGFEVDFTKIALACGYKYALVVESASSLNEVLKTVNEMQGP
                     VFLEVKVKKKVLEKI"
     CDS             7441..8562
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_157"
                     /sec_met_domain="Fe-ADH (E-value: 6.1e-84, bitscore: 275.6,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQRIYIGEASLNNLDIILQEYSAKKVFLVRGKKSYELCGAQSRL
                     NSILKKVGVQIFEFHDFEENPKIEDLDRGLLQLRVYHPDLILAIGGGSVLDMAKLLRFF
                     YSYSGNKIGRVFEKIENLLPLIVIPTTAGTGSEATSFAVLYKNKVKYSVSHEDILPEIA
                     FIDPYFTYNISRYLTACTGFDALAQAIEAYWNLNATNESDVFAVKAIKLLWPNLPLAVN
                     NPTKEVRNSMSEGAYWAGCAINITKTTAPHAFSYPFTTYYGYPHGHAVALTFPFFMEYN
                     VGSILLKHGTIFDKMIRLMEILNITNVNECKSLLCDYIENIGLDLKLPANFDHRIILSN
                     INVQRLSNNPVRIDGAVAKTALNTLCIKDDDKD"
     CDS             8568..8771
                     /locus_tag="ctg5_158"
                     /transl_table=11
                     /translation="MKIKKSLDSYKVIFQNTFYLSIIEAIRLIMPFIALPYIITTIGAT
                     NYGIIIFLKRLFHIFQLLLIGD"
     CDS             8822..9496
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_159"
                     /sec_met_domain="Polysacc_synt (E-value: 4.6e-23, bitscore:
                     75.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIVSTVFTIKFILFGLCFSIFMICLFFIPFFQQYRIIYLYAFL
                     SCFSEVIIPVWFFQGIEKMKYLTYIRTTSIVLYTILVFTFIKKEMDFTLLALLQSLANI
                     TAGVFSLILLLIFCRVKFVFPTFRVMKETFCNSTPFFVSRVSFLLNTNIAKTMSGLFLN
                     MHTVAAFDLSQKILSFVSVPIQMLNQAIYPHVAKNPIKSFSVKMLYVIAALSLILSVLL
                     FF"
     CDS             9816..10601
                     /locus_tag="ctg5_160"
                     /transl_table=11
                     /translation="MEKISNYNTDGTMLRKQQERMFEMLCVIDDICVKNEINYWLSGGT
                     LLGAVRHGGFIPWDDDLDIQLMKDDYNKLLGLLKTELPEQYQLQTSKTDRNYFARYAKV
                     RDVNSLLEDSDYTLGYKYKGIFIDIFSVEKANKFLVKISAFMQWYLLISLLPMVHKKTK
                     MQLNLFSLWNKFLGTFYSGFRLFGKLFAKKINYSYGVYYPLNCDYTTIFPLTTIEFEGR
                     MFKVPGNYNLYLCNIYGDYMKLPPEEERENHNIRVVHIV"
     CDS             10936..11757
                     /locus_tag="ctg5_161"
                     /transl_table=11
                     /translation="MVCIKSFLIINIIKQISSNVTYSEVNDSTILAEQETNLFSIFSNF
                     SICLYLTIILFYNKLYSKRIIFFSWLLLSLNIITVLAHGARMQVIFYLFVFVYYLFSSA
                     LNKKRFFLYMSFLIGIIYLCSYILPAVAYIRSGGNFTVEDLRKSYENYGEANAFVLQLL
                     IKSNSINTGAILVEETKEKPYLNPYINSIYSFCPSILFPGKRPLAGSSDGTIDGFPTRL
                     AAEYISGDSRFFNVGISTSATALWHGGILFYVINLIIVFFLVSFSEFINVL"
     CDS             11934..12941
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_162"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.6e-37,
                     bitscore: 120.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSEKIFFEFIIMNNPILLSIVIPVYNVELYIERCLLSCLNQDLS
                     ISQYEIILIDDGSPDSSIDKISKWLDRKNITLLTQPNSGLSVARNNGLLHAKGKYVWFV
                     DSDDWILENCLQEIAGYMVAGIDIITFCAADFINDKFYRRFEYITGVNKKIEGRDLLKR
                     GTCQHCVPFSIYRKRFLEQNHLFFLPNIFHEDTEFSPRAYYLANHVFCINKVFYYVYHN
                     PNSITRTFNPKKSFDLLIVSHSLSIFMLDVTPEYKSCFNNLISLSINAAINGIVTAKSE
                     ISRFIVDLTARGLYRNMLNAGKLRYKIEGLLLYLCPALLICLYKHYSSLRRIIK"
ORIGIN
        1 ttaccgccca atctggttca gtcttttcat gaactggaga gggtgaaccg taccgattgg
       61 ttttgtactt ccgacccggt aggtaagaaa cttggttccg gtggtggaac atcctggttg
      121 cttgaagaat gttataatga atattcagat ggtgctactt ttggagagtg gcttgaaaaa
      181 gaaaaagaat tcttcttcat gcgggtgggc aaagccgtcg tttacccggc tatgcacctt
      241 ctggaaagat tctcactccg gttcctgtgt tccggtggga gagagggcaa catctgggac
      301 aaaatctgct ttctctgcaa cttcccctat atgaaaaaat catgtctttg gctccggata
      361 aactccatac actgattgcg agtggtgatg tctatattcg ttcggagaaa cctttgcaga
      421 gtattcccga agcggatgtg gtttgttatg gactgtgggt agatccgtct ctggctaccc
      481 atcatggtgt gtttgcttcc gatcgcaaac atcccgaaca actcgacttt atgcttcaga
      541 agccttcgtt ggcagaattg gaatctttat cgaagaccca tttgttcctg atggacatcg
      601 gtatatggct tttgagtgac cgtgccgtag aaatcttgat gaaacgttct cataaagaaa
      661 gctctgaaga actaaagtat tatgatcttt attccgattt tggattagct ttgggaactc
      721 atccccgtat tgaagacgaa gaggtcaata cgctatccgt tgctattctg cctttgccgg
      781 gaggagagtt ctatcattac gggaccagta aagaactgat ttcttcaact ctttccgtac
      841 agaataaggt ttacgatcag cgtcgtatca tgcaccgtaa agtaaagccc aatccggcta
      901 tgtttgtcca aaatgctgta gtgcggatac ctctttgtgc cgagaatgct gatttatgga
      961 tcgagaacag tcatatcgga ccaaagtgga agattgcttc acgacatatt attaccgggg
     1021 ttccggaaaa tgactggtcg ttggctgtgc ctgccggagt gtgtgtagat gtggttccga
     1081 tgggtgataa gggctttgtt gcccgtccat acggtctgaa tgatgttttc aaaggagatt
     1141 tgagagattc caaaacaacc ctgacgggta ttccttttgg tgaatggatg tccaaacgcg
     1201 gtttgtcata tacagatttg aaaggacgta cggacgattt acaggcagct tccgtattcc
     1261 ctatggttaa ttctgtagaa gagttgggat tggtgttgag gtggatgttg tccgaacccg
     1321 aactggagga aggaaagaat atctggttac gttccgaaca tttttctgcg gacgaaattt
     1381 cggcaggtgc caatctgaag cgtttgtatg cacaacgtga agagttcaga aaaggaaact
     1441 ggaaagcatt ggccgttaat catgaaaaaa gtgtttttta tcaacttgat ttggccgatg
     1501 cagctgaaga ttttgtacgt cttggtttgg atatgcctga attattgcct gaggatgctc
     1561 tgcagatgtc acgcatccat aaccggatgt tgcgtgcgcg tattttgaaa ttagacggga
     1621 aagattatcg tccggaagaa caggctgctt ttgatttgct tcgtgacggc ttgctggacg
     1681 ggatcagtaa tcgtaagagt accccaaaat tggatgtata ttccgatcag attgtttggg
     1741 gacgtagccc cgtgcgcatc gatatggcag gtggatggac cgatactcct ccttattcac
     1801 tttattcggg aggaaatgtg gtgaatctgg ccattgagtt gaacggacaa cctcccttac
     1861 aggtctatgt gaagccgtgc aaagacttcc atatcgtcct gcgttctatc gatatgggtg
     1921 ctatggaaat agtatctacg tttgatgaat tgcaagatta taagaagatc ggttcacctt
     1981 tctctattcc gaaagccgct ctgtcattgg caggctttgc acctgcgttt tctgctgtat
     2041 cttatgcttc attagaggaa cagcttaaag atttcggtgc aggtattgaa gtgactttat
     2101 tggctgctat tcctgccggt tccggtttgg gcaccagttc cattctggct tctaccgtac
     2161 ttggtgccat taacgatttc tgtggtttag cctgggataa aaatgagatt tgtcaacgta
     2221 ctcttgtcct tgaacaattg ctgactaccg gcggtggatg gcaggatcag tatggaggtg
     2281 tgttgcaggg tgtgaagctt cttcagaccg aggccggctt tgctcaaagt ccattggtgc
     2341 gttggctacc cgatcattta tttacgcatc ctgaatacaa agactgtcac ttgctttatt
     2401 ataccggtat aactcgtacg gcaaaaggga tcttggcaga aatagtcagt tccatgttcc
     2461 tcaattcatc gttgcatctc aatttactct cggaaatgaa ggcgcatgca ttggatatga
     2521 atgaagctat acagcgtgga agttttgttg agtttggccg tttggtagga aaaacctggg
     2581 aacaaaacaa agcattggat agcggaacaa atcctccggc tgtggaggca attatcgatc
     2641 tgataaaaga ttataccttg ggatataaat tgccgggagc cggtggtggc gggtacttat
     2701 atatggtagc gaaagatccg caagctgctg ttcgtattcg taagatactg acagaaaacg
     2761 ctccgaatcc gcgggcacgt tttgttgaaa tgacgttatc tgataaggga ttccaagtat
     2821 cacgatcata aaaatagtat tggttgacga gaggtaaggg ttttatctct cgtcgacttc
     2881 tttttccatt cctcattaag tttgcctctt ctgttattct gatagtaaaa tagagatcct
     2941 gatatcttta agtctgcttt tttcttgttt taaaaacctt gttgtcttga gaaagtgatg
     3001 aaatagcaaa tgatggagca gtaacttgcc tttaattcgt ttcttcgtac gtgtactctt
     3061 catacgaagt taacttcgtc tttgcaaaac attaacttct tgtgaagaag aagttagtta
     3121 taagaaaata cgaagttaac ttcgtatagt tacgaaattc attttcattg aaaatcctcc
     3181 tacttttgcc tggcggtttc atttattgaa caagaactat agaattcttt tctgtagcat
     3241 aggtcaatat gaatcattcc tgaatgttat tttggaggta taggatgcct tttccgttgc
     3301 ttactgattg aaattagtgc atgtttatcg atcttttgac tggtgatttg atttattggg
     3361 tggagatatg atattggtga aaatagaatc ccggtgtttt ttataacaac ttagtcagtg
     3421 gtccgtaaat aagggattcc tgaggctact caaaatacaa tgtgacagaa tgcttttggg
     3481 agtatatagt ttctaaacct ttatagatag aataatgaag agtttatctt gttgtgtaat
     3541 ttgtttataa tcagtctgtt gtgtggtaaa tgcgaaaagg ataaaaaggg tgatttcttt
     3601 tgtaattaac tgataatcag cagtgaatgt gtttcaaaag acgttcgttt aatagcacaa
     3661 aggtataaac taaattttga tgtgcaaaat atttttagat gaaaaactaa atagacttct
     3721 ttatgtactg attatcagat aataatctgg taataaaaac agctttttac ttattttgta
     3781 tgtgggcttt tatctccata attgatgttt caaaagacga acgttttttg aaacatcaat
     3841 tgatcgaatc cgttcgtttc cacctaaaat aagtcataaa aaatcttgca gtttggctga
     3901 gaaaaagagt ctcacccaac tgcgaagcat acccggactt aagtaaatca cttaggaata
     3961 ttccttctaa atgtctcaac aacaagaata ttggttcgct gcccgtaccc gtaaggatca
     4021 ggagcttact actcgtgacg cattagagaa aataggtgtc gagtattttt tgccgaccca
     4081 atttgtcatt cgtcaattga aatatcgccg gcgtcgtgta gaagttcctg tcattcgtaa
     4141 tcttattttt gtacatgcta ccaaagagtt tgcttgtgct attgccaatg aatacggggt
     4201 gcgtcttttc tatatgcgtg attttgacac taagagtatg cttattgttc ccgataagca
     4261 gatgaaagat tttatgtttg tcatgaatct cgatcctgct gctgttatcc tcaacgatga
     4321 ttgtttcgca gttggcacca aagtacaagt catcaaggga gatttttgtg gagttgaagg
     4381 tgaactggcc agtctttcta atcgtactta tgtcactatc cgaattcgtg gcgttttatc
     4441 tgccagtgtc aaggttccta aaagctacct tcgcattctc gcaccgtaat cagtaatatt
     4501 ttatcatata aaatgaatac tcttatgacc cagattcatg agctgcaaca tgtggctcac
     4561 gaattattgt atttgggtgc tgacggttct cctatctata ccgacagttt ccgtcaatta
     4621 aacactgaag tgcttcaaaa atctgatgct ttgtttgctt tgaaaggaga aaatccggaa
     4681 gaagaagcac gactttgcct ggctctcttg atgggctaca atgcaacaat ctatgattat
     4741 ggcgacaagg agtctaagaa acaggttatt ctggatcgtt ccttgcttgt gttagagtct
     4801 ctcccgtctt ctttgctcaa gtgtcagctt ttgacatatt gttatggaga agtttttgaa
     4861 gaagagttgg caaaggaagc tcatgcaatt atagatggtt ggaaagatcg agaattgtta
     4921 gaagaagaaa gagaaatagt tgaaaatttg aggattttgg aagaacctcc atatctgttt
     4981 agtaataaat cttgttagaa atgaaaaaga aagtatatgt tgggatgagt gctgatatta
     5041 ttcatccagg gcatttgaat attattcatg aagcacaaaa actagggaat gtgactgtag
     5101 gtgttttaac agatgctgct atagccagtt ataaacgttt accttattta acttatgaac
     5161 aacgttcctt aatagtacaa aatctaaaag gtgttgatga agttattcca caaactacct
     5221 tagattatat tcctaatctt gaattgctaa aacctgattt tgttgttcat ggagatgatt
     5281 ggaaagaagg cgttcagaag gaaacaagac aacgggttat tgaaactctt tctaaatggg
     5341 gcggacaagt tattgatata ccttatacac aaggtatatc ctcaacaaaa ctcaattcaa
     5401 agcttaaaga aatagggaca actcctgaag tgcgtttgaa aagattaaaa cgtttgattg
     5461 aagctaagtc cattgttcgt atttgtgaat cacatagtgg attaacgggg ttaatcatag
     5521 aaaatacgtc tgttgaggta aatggtatga agcgtgaatt tgatggaatg tggtctagta
     5581 gtttaactga ttcaacatca aaggggaagc ctgatattga agctgtagat ttgacgaccc
     5641 gtttacatga tttaaatgat gctttggaat gtacaacgaa acctgttatt tttgatggtg
     5701 atacaggagg aaaaattgaa cattttgttt ttacagttcg tacgttagaa cgtttgggta
     5761 tttctgctat aataattgaa gataaagttg gattgaaaaa gaattcttta tttggaactg
     5821 atgttattca gacacaagat acaattgagg gtttttgcga taaaatatca gcaggaaaac
     5881 gtgctcaaat aacggatgac tttatgatta ttgccagaat tgaaagtttt attgctggta
     5941 aaggtttaga tgatgctatg aaaagagcat tagcttatat tgaggcggga gctgatggta
     6001 taatgattca cagtaaagat aaatcaggtg aagatattag acttttttgt aaggcgttac
     6061 gagaggttaa tcaatcaatt cctatagtag tagttccgac aacttataat catataacag
     6121 atgaagagtt gtctacatgg ggtataaatg tggtcattta tgcaaaccat atgttacgta
     6181 gtgcttatcc tgctatgcta aatactgcga aatctatatt attacatgcc cgttcatatg
     6241 aggcaaatga tttatgtatg ccagtaaaag atatattaga attaatacca ggtacaaaat
     6301 agttttttta tgatttctcc agaacttttc attaactctc ttgtacaaaa tgaacttaat
     6361 ttttttacag gggtaccaga ctcattattg aaacatattt gtgcctatat aactgatcat
     6421 atagcttcaa atagtcatat agttgctgcc aatgagggag cagcgattgg tttggctgtt
     6481 ggttatcatt tggcaactaa taaaattccg gttgtatata tgcaaaattc cggtattggt
     6541 aattctatta atcctttatt atctttagta gacaaggagg tgtataatat tcctttatta
     6601 ttattagtcg gttggagagg tgagcctggt gtaaaggatg aacctcaaca tataaaacaa
     6661 ggtaaggtaa ctattccttt gtttgattct atgcgaataa agaaccagat actttccaaa
     6721 gataaatctg atttcttaca acaactaaac gtagcattag aatatataag agagacaaat
     6781 gagccttttg tttttataat tcagaaagaa acattcagtg attataaact gcaaactcca
     6841 aataataatg ctttgttatt ggatagagaa actgctatta agattattgt ttcttctatt
     6901 tctaagaatg atatagtcgt ttctactaca ggaatgatat ctcgtgagct atttgaatat
     6961 agggataaca tgggcgaatc tcatgaaaag gactttttaa cagtcggttc tatggggcat
     7021 gcctctcaaa tagctttggg tattgcatta caaaaaaagg ctagaactgt gtattgtttt
     7081 gatggtgatg gtgctgtttt aatgcatatg ggaggactaa caaccattgg atcaataaaa
     7141 ccgtctaatt acatccatgt attatttaat aatggagcgc atgattctgt aggtgggcaa
     7201 cctacggttg gttttgaggt agactttaca aagatagctt tggcgtgcgg ttataaatat
     7261 gctttggttg tggagagtgc ttcatcttta aacgaagttc ttaaaacggt gaatgaaatg
     7321 caaggacctg tttttttgga ggttaaggta aagaaaaagg tgctcgaaaa gatttaggtc
     7381 gtcctacaat aactccaata caaaataaag actcttttat ggacttttta aagcgataat
     7441 atgaaacaac gcatatatat tggagaggcc tcattgaata atttagatat tattttgcag
     7501 gaatattctg caaagaaggt ttttttggtg agagggaaga aatcatatga gctttgtgga
     7561 gcacaatcaa gattaaactc tatattgaag aaagtaggag ttcagatctt tgaattccat
     7621 gattttgagg aaaatcctaa aatagaagat ttagatagag gacttttgca attaagagtt
     7681 tatcatccag atttgatact tgcaatagga ggaggcagtg tattggatat ggctaaattg
     7741 cttcgttttt tttattctta ttctggaaat aaaataggaa gagtttttga aaaaatagaa
     7801 aatctattac ctttaattgt tatacctaca actgcgggaa ctggcagtga ggctacgagt
     7861 tttgctgtgt tatataagaa taaagttaag tattctgttt cgcatgaaga tatattacct
     7921 gaaatagctt ttattgatcc atattttaca tataatattt ctcgatattt gacagcttgc
     7981 acggggtttg atgcattggc ccaggctatt gaagcttatt ggaatttaaa tgctacaaat
     8041 gaatctgatg tttttgcagt aaaagcaata aaattacttt ggcctaattt accattagcg
     8101 gtaaataatc caacaaaaga ggttagaaac agtatgtctg aaggggccta ttgggctgga
     8161 tgtgcaataa atataacgaa gactacagca cctcatgctt tttcttatcc atttactact
     8221 tattatggct atccacatgg acatgcggtg gcattaactt tcccattttt tatggaatat
     8281 aatgtaggaa gtatattatt aaagcatggt acaattttcg ataaaatgat tcgattgatg
     8341 gaaatactca atataaccaa tgtaaatgaa tgcaaatctt tactatgtga ttatatagaa
     8401 aatatcggac ttgatttaaa gttgcctgcc aattttgatc atcgaattat tctttcaaat
     8461 ataaatgtgc aaaggttgag taataaccct gtacgaatag atggggctgt ggctaaaaca
     8521 gctttaaata ctttatgtat caaggatgat gataaagatt gatagtgatg aaaattaaaa
     8581 agtctttaga ttcctataaa gtaatttttc aaaatacatt ttatttgtcg ataattgaag
     8641 ctatacgctt aataatgccc tttatcgctc ttccatatat tattactact attggcgcaa
     8701 ctaattatgg gattatcatt tttctcaaac gattgtttca tatttttcaa ttgttattaa
     8761 ttggggatta gatgtaactt cagtccgaga agtgtcttta aatagaggta gtttaaaaaa
     8821 aatgagttta atcgtttcta ctgtatttac tattaaattt attttgtttg gactttgctt
     8881 ttctattttc atgatatgtt tgttttttat ccctttcttt caacaatata gaattatata
     8941 tctgtatgct tttttgtcat gcttttctga ggttattata cctgtgtggt tttttcaagg
     9001 tattgagaag atgaagtatt tgacttatat aaggacaaca agtatagttc tctatactat
     9061 acttgttttt acttttatta aaaaagaaat ggactttaca cttttagcct tattacaatc
     9121 tttggctaat attactgcag gtgtattttc attaatatta ttattaattt tttgtagagt
     9181 caaatttgta tttcctactt tcagagtgat gaaagaaact ttttgtaata gtacaccgtt
     9241 tttcgtttcc agagtttcgt ttttattgaa tacgaatata gctaaaacga tgagtgggtt
     9301 atttctgaat atgcatactg ttgccgcatt tgatttgtct cagaaaattt tatcttttgt
     9361 gtctgttccc atacaaatgc tgaatcaggc gatttatcct catgttgcaa aaaatccaat
     9421 taaatcattt tctgtaaaga tgctatatgt tatagctgca ttatctttga ttttatctgt
     9481 tttacttttt ttctagcacc ctatatcatt ctttattttt cagcgcaact atatgctgaa
     9541 gctctaattt ttataaggat cttgtgtctt tatgtatttt gttttggtat taatacttat
     9601 ttagggactc cacttcttgt cgcttatggt ttttataagc catttaactt cagtgtaata
     9661 tattctactt tatttgtgtg ctctttgtac gggattttat acgtatttaa tttattgggt
     9721 ggggagtgct ttgctttagc aatgttctta acagagcttt ttattctgat atatagattt
     9781 tattattgtt tgaaatttaa attgatataa aaataatgga aaagatatct aactataata
     9841 ctgatggtac tatgttgcga aagcaacaag aacgtatgtt cgaaatgtta tgtgtaatag
     9901 atgatatttg tgtcaagaat gaaattaatt attggttatc tggtggaact cttttaggag
     9961 ctgttaggca tggaggtttt ataccatggg atgatgattt agatattcaa ctgatgaaag
    10021 atgactataa taaattacta ggtttattaa agacagaact tcctgaacaa taccagttac
    10081 aaacatctaa gactgataga aactatttcg caagatatgc gaaagtaaga gatgtgaatt
    10141 ctttgcttga agatagtgat tatactttgg gatataaata taaagggata tttatagata
    10201 ttttttctgt tgaaaaagca aataaatttc tagtaaagat atctgctttt atgcaatggt
    10261 atctattgat ctctttgtta cctatggtac ataagaaaac taaaatgcaa ttgaatcttt
    10321 tttcattatg gaataagttt ttaggtactt tttattctgg attcagacta tttggtaaat
    10381 tgtttgccaa gaaaattaat tattcttatg gagtttacta tcctttaaat tgtgattata
    10441 ctactatatt tccattaaca acaattgagt ttgaaggacg tatgtttaaa gttccgggaa
    10501 attataattt atatttatgt aatatatatg gtgattatat gaaacttcct ccagaggaag
    10561 aaagagaaaa tcataatata agagtggttc atattgttta gttctcacta tatttatgtt
    10621 aatagtaata ctactgactc taatcttaat atatatatta tataagatat ataaaaaaaa
    10681 gaaggttcat caatttttac tcatatattt tgctttttct gcttttttgt gggttatttt
    10741 tccatcgatt gtttctttaa taggagatag atataaacag gaattggtag taaaagaaaa
    10801 tgtttttata acttatgcta tttatgaatt tcttttttat ataatattgt tacttttact
    10861 ctatcgtttt ccattatgta aacctttcta ttatgggaaa tatattccca atacatcctc
    10921 gtctataaaa cgaatatggt ttgtattaag tcttttctca ttattaatat tatcaagcag
    10981 atatcttcca atgttactta ttctgaagtc aatgattcaa ctatattggc tgaacaggaa
    11041 actaatttat tttcaatttt ttcaaatttc tctatatgcc tatatcttac tataatatta
    11101 ttttacaata agctttattc aaaaagaatc atttttttct cttggctatt actatctctt
    11161 aatataataa cggttttagc tcatggagca agaatgcaag ttatttttta tttgtttgtt
    11221 tttgtatatt atttattttc ttctgcatta aataaaaaac gttttttctt atatatgtct
    11281 tttctgatcg gaattattta tttatgttct tatattcttc cggcagttgc atatataagg
    11341 tcaggaggaa attttacagt tgaggatttg agaaagtcat atgagaatta tggggaagca
    11401 aatgcttttg tccttcaatt gctgattaag tctaatagta taaatactgg ggccatttta
    11461 gtagaggaaa caaaagaaaa gccatacttg aatccatata ttaattcaat atattcattc
    11521 tgcccaagta tactctttcc tggaaaaaga cctttggcag gtagtagtga tggtacgatt
    11581 gatggattcc ctacaagatt agccgcagaa tatataagtg gtgattctcg tttctttaat
    11641 gtgggaatat caacttctgc cacggcacta tggcatggtg gtattttatt ttatgtgatt
    11701 aatttaatta tagttttttt tttggtatcg ttttctgaat tcattaatgt tttatgaaaa
    11761 ctactatgca aaacttttag ttgtatattt tacagttttg gggtatttta tacttcctac
    11821 ggcagatgtc ttaatacggg atttgcttaa acagcctttc ttttatgcat tctttatatt
    11881 tatctcgaga ggtggtctta ttaaagattg ggttagatct ttgaaacgtc atattgctta
    11941 gtgaaaagat attctttgaa tttatcatca tgaataatcc catactttta tctattgtaa
    12001 tccctgtata taatgttgag ttatatattg aacgttgtct attaagttgt ttgaatcaag
    12061 atctttcaat atcacaatat gaaatcattt taatagatga tggaagccca gatagcagta
    12121 tcgataagat ttcaaaatgg ttagatagaa aaaatataac tttgttaact cagcctaata
    12181 gtggattaag cgttgcacga aataatggat tactacatgc aaaaggtaaa tatgtttggt
    12241 ttgttgattc cgatgactgg attttagaaa attgccttca agagattgca ggttatatgg
    12301 ttgctggaat tgatattatt actttctgtg ctgcagactt tattaatgat aaattttatc
    12361 ggagatttga atacataaca ggtgtaaata aaaaaatcga aggaagggat ttattaaaaa
    12421 gaggaacttg tcaacattgt gtgccatttt ctatatatcg gaaaagattt ttagaacaaa
    12481 atcatttgtt ctttttgcca aatatttttc atgaagatac agaattttct ccacgggcat
    12541 attatttagc gaatcatgtt ttttgtatta ataaggtatt ttattatgtg tatcataatc
    12601 ctaattcaat aacaagaaca tttaatccga aaaagtcttt tgatttatta attgtatctc
    12661 acagcttgtc tatattcatg ttggatgtta ctcctgagta taaatcttgt tttaataatt
    12721 tgatttcttt gtctataaat gctgcaataa atggcattgt tacggcaaaa agcgagattt
    12781 ctaggtttat agtggattta actgctagag gattgtatcg aaacatgctt aatgccggaa
    12841 aattaaggta taaaatagaa ggattactac tctatttatg tccggcattg ttgatttgtc
    12901 tgtataaaca ttactcttca ttgagaagaa ttattaaata atctaataaa aatgttatgg
    12961 tgtttgttaa accaattaag attgccgtaa taggtcttgg ttatgtcggg ctacctttgg
    13021 cccgattgtt ttcgacaaaa tatgaatgta ttggttttga tctgaaccag tctcgtgttg
    13081 atgctttaaa ttccggtcat gatatgactt tagaggtttc tgatgactta cttcggaaag
    13141 cgttagaaaa tggtttcaaa tgtaccagta atattgacga aataagtaat tgtaactttt
    13201 atgttgtagc tgtaccaacc cctgtggatt tgaataatcg tcccgatctt acacctttga
    13261 ttggtgcgag tacaacagtc ggaaaagtta tttcaaaagg ggatattgtt gtgtatgaat
    13321 ctactgtata tccgggagta acagaggaag aatgtcttcc ggtagtcgaa gaggtgtctg
    13381 ggttaacata caatgtagat ttttatgcag gttattcacc agaacgtata aacccgggtg
    13441 ataaagagca tactgttgaa aagattaaga aagtaacttc cggttcgact cctgagattg
    13501 ctgacattgt tgattatgtt tataattcag tgttggttaa cggtactcat aaagcccctt
    13561 ct
//
