LOCUS       gnlProkkaOBCGCHNO_285  14656 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBCGCHNO_285.
ACCESSION   gnlProkkaOBCGCHNO_285
VERSION     gnlProkkaOBCGCHNO_285
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:11:47
            Original ID  :: gnl|Prokka|OBCGCHNO_285
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14656
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14656
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2258:4952]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2259..4952
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14656
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14656
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(2..658)
                     /locus_tag="ctg189_1"
                     /transl_table=11
                     /translation="MYLKSRVKLPDVHGKLTRLRRGDITYIKYEYDRYYDPEKKYTYPQ
                     RATIGKVCPDDDTMMIPNEAFLKYFPDAVLSGMEDRTERSSCLRVGTYAVMHKIVLDYS
                     LDKLLGQFFSERDMALLLDLASYSIVEESNVAQHYPDYAYNHPLYSSGMKIYSDASVSD
                     FFKSITKDKSTGFLNEWNAKRNRRERIYISYDSTNKNCQAGEIELAEFGHAKTDIG"
     CDS             complement(1151..1381)
                     /locus_tag="ctg189_2"
                     /transl_table=11
                     /translation="METTVMNVAVSQGIWAVLAVFLLIYIVKSNEQRDTKQEEREKNYQ
                     TVIESLTEKFQILNQVQSDLKEIKDNLFNKN"
     CDS             1682..2206
                     /locus_tag="ctg189_3"
                     /transl_table=11
                     /translation="MKTLTELIQNYQNGIPDSDSEILKRMEPLVKGYASRIHCMEREDS
                     TQELYLTLLKTLPYLSSSSSEGECIRYMQTSVENRYRSLCRSCLSEPEKDDFDSCSVSL
                     QAPDSFDDTYYDVTAYINSYPSDSVQRKILSMYFYQDKSDAQIARKLKLSRQYVNRMKK
                     KLILRYISENK"
     CDS             complement(2259..4952)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     763.1; E-value: 7.2e-231)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg189_4"
                     /sec_met_domain="DUF4135 (E-value: 7.2e-94, bitscore:
                     304.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-52, bitscore:
                     168.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLKLDYLCRKNRTMFLKILILDVHRQKNFGNLKGSTPKEQYDYY
                     EKKYLNNATYVKSLLQEYPELKRLLELKNNSIQRAECEIRKSLYAEKEQIQKIFCDGRK
                     FSGTVGIYMSKGDIHRGGRSVAKVELDNGTILYYKPHSLDKNIKYQELYNYLCRKTGIS
                     CRTVQYLSHDSYGWEEKIENIPCKNESEVEHYYFRMGIHLFLGYALGATDLHGENIIAH
                     GEYPVIIDMETYPGYLKQQSEKDGSSVEEKINKSTEIKLANSVIHTGMLPVLTWGRGNR
                     GVLISAMGTEEKIKTPFKLPVVKDDKTSDIHIEYEPVEMQIKECIVRLNDQVINAADYT
                     ECIIRGFCRAYMVAMADKKVEVMLSGFFDGRSRVVLRHTQQYAMYLMASFHPDYMKSRE
                     CRKALLNVIHKEGESSFMKEIHDYEIDSLLEMDIPCFEIDANSRSVYDGNGGEHKEYLP
                     CTPYESWRMHMKQMSYSDMECQCDYIRLSMEMLKASDGKKKMFPTRIKGYDTDKERKIY
                     SQIRKIVHRICSRAIIREQSAGWAGLQFWDNGHWNLRSGGIYLYDGISGIVLFLAKYLH
                     DFEEKNASAEEIYHLAVLRLKAYTDEIHKKQIYDKNLLTGIVNGESSVVYTYLYLFKLT
                     GKRVWMIYAEKHFSIIERVWKEDSQLDYLSGNAGAIVVAVMLYKETGNLKYYEIAADME
                     KDLWKKGQETGNGYGWRLKGTDGPLAGMSHGNSGFLMAYAALYECNHKAEYADKIQLLL
                     RYEDSLYSEKAGNWKDLRESSGESFMNAWCHGAPGILLSRMKLEELFPEDMQIKKDRLN
                     AADSLFYGEQDEKICLCHGMSGNLLIMKKYLRKYGNKKMKEQYEALCDCLLFQLDHPAK
                     ISGTEYLNLAFMNGISGTGMALMEIL"
     CDS             complement(4943..5071)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg189_5"
                     /transl_table=11
                     /translation="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYGTIVCC"
     CDS_motif       complement(4961..5071)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /locus_tag="ctg189_5_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4943..4960)
                     /prepeptide="core"
                     /locus_tag="ctg189_5_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.90"
                     /molecular_weight="519.7"
                     /monoisotopic_mass="519.2"
                     /core_sequence="TIVCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEMNDKIIGNVEKELDEIEIIDTESIEEKLSFIVYG"
                     /leader_location="[4960:5071](-)"
     CDS             complement(5088..6569)
                     /locus_tag="ctg189_6"
                     /transl_table=11
                     /translation="MLKVLLYGLATFMETGIGVWIFSQTFSERRILEKKYYVLEWLLYS
                     LIFFGIYNFSVSLWQIDKKIEKYVIKVICIYIIGLIAGIIYDIFFVKKKEMVLRRILYI
                     GMIFWLTAQYWAGYQSLLMIILGSGIIVLYVFCYFDCTFKQAYVWNFFYAVNIGLIKEA
                     YVVYAGVFNHKQWDDFYSYPRGHTYQEVIFWILGCLFIFWIIKFILSVNSIKGILRTRL
                     KELFIIGLLEYVLLIVSIIYKFGTIKKENFVMTACLLAVSNIALIGVYVKFQKKTLEMR
                     NQILDMRCKLMEEEYEELRMSYDRYRCLVHDEKHLLLYIKECLENGELDSCITFLNHYK
                     RESIRYSGVAWTGIPEINFMLNIKVRKMEEKNIFFKVDSKIEKIPMKDIDFVVLLGNLL
                     DNAIEAAEKCEEGKGKITCIFRNINDMFIFKVKNTSIYKPYEKNTKFYTSKKEKDEHGW
                     GIESVKQIVRKYNGEIDFKYDKDFFEVEIIISDNT"
     CDS             complement(6573..7280)
                     /locus_tag="ctg189_7"
                     /transl_table=11
                     /translation="MIRIMILDDDEMYLKKEKEITEHYFAEKNIDCTVTTYQNVEWFLL
                     GLKEEKFDMYLLDIRMPGENGIEAAREIRRLYPNPVIIFITNFVDYAIEAYEVNTYRYI
                     PKECLKEKLSQAYDALLPVIMEKEERYYIINKRNEVEKLAYSDIFYMKKEGKYVIFVHR
                     RGEVKIRASLSTIEKELNSKEFIISDRGYLANIQHVMKMKGRDLYMRDGNIITVGRERF
                     KGVREAILNYWGV"
     CDS             complement(7286..7840)
                     /locus_tag="ctg189_8"
                     /transl_table=11
                     /translation="MDEYTKDLYTMMFSLQTLQNQGITIRETVYKSLDKLLLWNKESEN
                     SKYLELALLHMQAYANMGFALDEENKTICEILKKTGKTREDFFPKGYLLGKRIKLTRSQ
                     VRGMIGRWRPSRDSPMTIGELVDDIIRKVKNHEEGRYIYQYHRTDVTTKEDIEVYELVI
                     NKDESYFYDVKKFRFYTFMEE"
     CDS             7959..8294
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.6; E-value: 4e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg189_9"
                     /transl_table=11
                     /translation="MKNNTIGKRIAEARINRNITQEHLEELSGLSVSTISRIETGKYMP
                     TIENLLKLSEILDVGLDYFLYDLLPHNKDIQSPAIQDAISIMNQMGERQTEYIVKILKI
                     YQASHQD"
     CDS             8482..9375
                     /locus_tag="ctg189_10"
                     /transl_table=11
                     /translation="MTKTEKAVTWAIRIANDPAHGYDQDNRWGPDYDCSSLVISAWQQA
                     GVPVKTKGATYTGNMKSVFLSCGFKDVTSKVNLSTGSGMKRGDVLLNIASHTVMHIGNG
                     QVVSASKNENNGYHGGKPGDQSGKEIKLQSYYNFPWDCVLRYTEDSSTTDPDPEPQPTA
                     GNAKIRKGQGYANKFANAGISITGKRDAATKKAGVKVLQTALNRDYGAGLDVDGIWGTN
                     TDNALGQHYVKNGETQYMVTAAEILLLLRAYDPNGVEIPGTFGSGLLSAVKAFQKAQGL
                     TVSGTCDRNTFLKLIS"
     CDS             complement(9521..10279)
                     /locus_tag="ctg189_11"
                     /transl_table=11
                     /translation="MKQKKIAIIMAGILAAAAAMTGCAEQNKTETQVDYTQNSQEKSEQ
                     TKQKTAEKSQPDKKQVNKSTSIGKEDSNQTADKKTKISASSNNAGDVQNSENGTDSTAG
                     TDTDDSQTTGVDTSASEDNGSTGNGGTQSDQRADQAMIYDSEGNGRLISEADDGNWYDS
                     DGNYYGSWEDIEDAMVNENGVTDQDGNKYYWTAPHDASEEVTDPYDLYSWDPGTNSYIP
                     FQAAESDCSPVGRGNGWYYYDEDSGEYVPW"
     CDS             complement(10519..13200)
                     /locus_tag="ctg189_12"
                     /transl_table=11
                     /translation="MKSNYKIFTAVFLSAIMTAAAPLTVCGAEVFSAGESFSDGTGSIP
                     AILTDMVLPGGEIGTEYQVQLEADTDVSWSLEEGSELPAGLTLSSGGVISGTPQKEGSF
                     SFTVQADNGIGVSSQELSLYVAQREQEPVIKQYELTSGTALINLGIHAEGEQSRKRLFL
                     YNAGTDSLHLSDFPQSRYFDFSYAPIFDTNTDEEMQPGSCAAVDIDDKKNLPAGNYEET
                     VTFETKEGASCKVTLKVIVGASSEKDYELSIETGTEEEFTESDFYDPEFRVEKYVVVRN
                     SGKKETRIRIDTSGLKNFEVDDQMAKWTEDYEEQDSKKLLKPGETLYFYILPKQEYGIY
                     DETFAFLADDGSRYPLHVTMNREKNPTEKKQLEITEKSAGGFPTMQWGYKTLPEAKTYI
                     LKNVTDTDMKLSFNRSKECSVLLSGNAYLAPGESTELRLWPKLGLSVGKYSFQVTVTAK
                     TVAGEHLTTQNLYNSFIVGDRTYQGLADAVAPVTGITNGAEKTADALHLPKSLEVYGAE
                     VNGEKTTFSASVKWDVENCAYDPKSKAAQSFLVNGSLELNEDENNEGLDTAVQIMVQVD
                     AYQTLNRPVIDTRWTRVITNYAMLYLRDLSNEADGYQFVTAKSQKDLKKGNYTAQTKIT
                     NSELNQYPELKYIPEGTHSLYCRAYKENSSHVMEYGEWSDGVPVTVKAKTPDAPVVQKV
                     QVKKNDVRIVLNSKGEEPDGYDVVAARSKNGKEPSDYIKVKSGYSGSSKELILRGVPAG
                     TWYIGVHAYKYLNGSNTKVLSKWAEVRKVTVKTSLVTGKPAVKSAKVSRQGTKRNVAVT
                     FTVPKSCDGTDWVLAKKVSKSDNGSYTGVSSYAYTKKNQTKTTVVFKNVKPGVYYLAGR
                     AYVKGYAKSYTKWSKIKKIVVK"
     CDS             complement(13395..14363)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 214.8; E-value: 3.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg189_13"
                     /transl_table=11
                     /translation="MKLGILGAGGIASTMAKTVAGMKDVEAYAVAARDLERARVFAQKY
                     EVKKAYGSYEEMLADDEVGLVYIATPHSHHYLHAKMCLEAGKHVLCEKAFTVNAEQAQK
                     LFDLAKEKKLLITEAIWTRYMPSRKMINDIIESGVIGEVTAVTANLSYTVSHVERIRKP
                     ELAGGALLDVGVYPINFASMVLGDKVKDVKATAIFQNGVDILDSIAMVFEGDRMATLQC
                     GAREISDRMGSIFGTRGYMQVQNINNPEKITVFDTEHKEVASYVVPEQISGYEYEVESC
                     MKAIHEGKTECPEMPHAETIRIMKIMDDIRKSWNYEIPCIE"
ORIGIN
        1 aaccgatatc tgtcttggca tgaccgaatt cagccagttc aatctctccg gcctgacagt
       61 tcttattcgt agaatcatag gaaatataaa tacgctccct tcgatttctc tttgcattcc
      121 attcattcag aaagcctgta ctcttatcct tggtgatgct cttaaagaaa tcacttaccg
      181 acgcatcact atagatcttc ataccagaac tatacagtgg atgattgtat gcgtaatccg
      241 gataatgctg tgccacattg ctttcttcta caatagagta agaggcaagg tcaagcaata
      301 atgccatatc ccgctcagag aagaactgtc cgagcagctt gtctaacgaa taatccaata
      361 ctattttatg cattacagca tatgtaccaa cccgcagaca gctgctacgt tctgtccggt
      421 cttccatccc tgataagact gcatctggaa agtatttcag aaaggcttcg ttaggaatca
      481 tcatagtgtc atcatctgga cataccttgc ctatagtcgc tctctgtgga taggtatatt
      541 ttttctccgg atcataatag cgatcatact catacttaat atatgtgata tccccgcgtc
      601 ttaatcgggt caattttcca tgcacatccg gtagcttaac tcttgatttc aggtacatat
      661 ttgcctcctt tattcaggtt tatatagccc taaatttatt gtacagcaca acccgtattt
      721 ttgcaataat ttccgcagaa atacgggctt ttttaaaatt ttattttcgt tagggctact
      781 catttttgga agttaaggag aaataaaaaa attttggcaa aagcaaaaaa gtagaaaaaa
      841 caccatgaaa aaatgacaaa acatagaagc cgcaatccag cataaacact tggattgcgg
      901 cctttttttt aatctatttt acactaccca aaagtcaggt tttattatca taatatacca
      961 tttactatac gaacatctgt aaatctggga ttaaaagtat tctaatggac acgaatgtta
     1021 tgcttatatt catctaccat tttagtaaac atatttttct caaattaacc tattttctta
     1081 cctaaaatga cagaagccct ctccgctgga aaaatatatc ctgcagaaaa ggcttttttc
     1141 ttttccctat ttaatttttg ttaaaaagat tatccttaat ctctttcaga tcgctttgaa
     1201 cctgattcag aatctgaaat ttctcagtta aactctcaat caccgtctgg taatttttct
     1261 ctcgttcttc ctgctttgta tccctctgtt catttgattt cacaatgtaa atcagaagaa
     1321 aaaccgcaag cacagcccag attccctgtg aaactgccac attcataacc gttgtttcca
     1381 tggtttctgc ctccttcctt aatcttcttt tattatgcaa actttttcta tgttttgtct
     1441 actaaaagtc ttttctaatc ttattattac cgttttaatt taaagcatat ttctattctc
     1501 tacaattatt ttgcaaatct ctttttacca tgtatttctt ctcctatcgc tgatctaaat
     1561 ttgcaacctc acttaataaa gagttttttc tcttccattt gtaaactcac aaattttttt
     1621 cttttttagt ttctgatcag cagttttctt actacttccc ctaaaaagga ggtagatacc
     1681 tatgaaaaca ctgacagaac ttatccaaaa ttatcaaaat ggtatcccag attcagacag
     1741 tgaaattctc aaacgtatgg aaccgcttgt gaaaggatat gcatcccgga ttcactgcat
     1801 ggaacgtgaa gattccacac aggaattgta tcttactctg ttaaagacat tgccatattt
     1861 aagttcttca tcctcagaag gtgaatgtat cagatacatg cagacctctg tcgaaaacag
     1921 atatcgttcc ctttgccgca gttgtctttc cgaacctgaa aaagatgatt ttgattcttg
     1981 ttctgtttca ttacaggctc ccgacagttt tgatgacacc tattatgatg taaccgcata
     2041 tatcaactct tacccttcgg acagtgtcca gagaaaaatt ctgtccatgt acttttatca
     2101 ggataaaagc gatgcccaga ttgcccggaa actgaagctg tcccgccagt acgtcaatcg
     2161 gatgaagaag aaactaattc tcagatatat ttccgaaaac aaataaaaga aacacctgct
     2221 gaccataaat ttacagtctg caggtgttcc cttagttttc ataaaatttc cattaatgcc
     2281 attcccgtac cggaaatgcc attcataaaa gccagattca gatattctgt cccagatatt
     2341 tttgccgggt gatccagttg aaataaaagg cagtcacata acgcctcata ttgctccttc
     2401 atttttttat taccatattt tcgaaggtac ttcttcataa taagtaaatt cccggacatc
     2461 ccatgacaca gacaaatttt ttcatcctgt tctccataaa acaaagagtc tgcagcattt
     2521 aacctgtctt ttttaatctg catatcctca ggaaacagct cttccagttt cattcgtgaa
     2581 agcaggattc ccggcgcccc atggcaccat gcattcatga agctttcccc tgaactctct
     2641 cgtaaatcct tccagtttcc ggctttctct gagtacagag aatcctcata tctcagcaaa
     2701 agctgtattt tatcagcata ttccgcttta tgattacatt catacaacgc tgcataagcc
     2761 atcagaaatc cactgttgcc atgagacatt ccagccagcg gtccgtctgt tccttttaat
     2821 ctccatccgt atccatttcc ggtttcctgt cctttcttcc acaaatcttt ttccatatct
     2881 gccgctattt cataatattt cagatttccg gtttctttat ataacatcac tgccactaca
     2941 atagctccgg catttccgct cagataatcc agttgtgaat cttctttcca taccctctca
     3001 ataatgctga aatgcttttc cgcataaatc atccacactc tttttcctgt aagtttaaac
     3061 agataaagat aggtatatac caccgagctt tctccattta caatacctgt cagaagattt
     3121 ttatcataaa tctgtttttt gtgtatttca tctgtataag ctttcaatct caaaacagca
     3181 agatgataaa tttcttctgc acttgcattc ttttcttcaa aatcatgaag atattttgca
     3241 agaaacaaga ctatcccgga tattccatca tataaataga ttccacctga tctgagattc
     3301 cagtgaccat tatcccagaa ttgcagaccc gcccagccgg cgctctgttc ccggataatt
     3361 gctctgctgc agattcgatg aactatcttt ctgatctgac tgtatatttt gcgctcttta
     3421 tctgtgtcat atccctttat cctggtcgga aacatctttt tctttccatc agatgccttc
     3481 agcatttcca tggacagcct gatataatca cactgacatt ccatatcaga gtaactcatc
     3541 tgcttcatat gcattcgcca tgactcataa ggagtacagg gcagatattc tttatgttct
     3601 ccgccatttc catcataaac agatctgctg ttcgcatcaa tctcaaagca gggtatatcc
     3661 atttccagaa ggctgtcaat ttcataatca tgaatctctt tcataaaaga agattccccc
     3721 tctttgtgaa tcacattcaa aagagctttc ctgcattctc ttgacttcat ataatccgga
     3781 tgaaacgaag ccataagata cattgcatac tgttgggtat gccgcagtac aactctggaa
     3841 cgtccgtcaa aaaagccgga caacatcacc tccactttct tatctgccat tgccaccatg
     3901 tacgctctgc aaaatcctct gataatgcat tccgtataat ctgccgcatt gataacctga
     3961 tcatttagtc ttacaatgca ttcctttatc tgcatttcca caggttcata ttctatgtgg
     4021 atatcagatg ttttatcatc ctttaccaca ggaagtttaa acggtgtttt tatcttttcc
     4081 tctgttccca ttgcacttat aagaactcct ctgtttcctc tgccccatgt gagaacagga
     4141 agcattcctg tatgtataac cgaatttgcc aattttatct ctgtactttt gtttattttt
     4201 tcttctacac tacttccgtc tttctctgat tgttgtttta aatatcccgg atatgtctcc
     4261 atatcgataa tcacaggata ttctccatgt gcaataatat tttcaccatg aagatctgtt
     4321 gctccgaggg catatcccaa aaacagatgt atgcccattc tgaaataata atgctccacc
     4381 tcactttcgt ttttacaggg aatattctca attttttctt cccatccata ggaatcatga
     4441 gataaatatt gtaccgtcct gcaggaaatt cctgtttttc tgcataaata gttataaagt
     4501 tcctgatatt ttatattctt atcaagacta tgtggcttat agtacagaat tgttccatta
     4561 tccaattcta ccttcgccac acttcgtcct cctctgtgta tatcgccttt cgacatgtaa
     4621 attcccacag tcccggaaaa ctttcttcca tcacagaata ttttttgtat ctgttctttt
     4681 tctgcataaa gagatttcct gatttcacat tctgctctct ggatagagtt atttttcaat
     4741 tcaagcagac gttttaactc gggatattcc tgcagtaaag attttacata tgttgcattg
     4801 ttaagatatt ttttttcata ataatcatat tgttcttttg gcgtacttcc ttttagattt
     4861 ccaaaatttt tctgccgatg tacatctaag attaatattt taagaaacat agttcgattt
     4921 tttctgcata aataatccaa tttcagcaac acactatagt tccatataca ataaaagaca
     4981 atttctcttc tatactttcc gtatctatta tctctatttc atctaattct ttttccacat
     5041 ttcctattat tttatcattc atttcgttca taaccgtcac tctcccatta tgtattatcg
     5101 ctaattatta tttctacttc aaaaaaatct ttatcatatt taaaatctat ttcaccatta
     5161 tactttctta caatttgttt gacactttca atcccccatc cgtgctcatc tttctctttt
     5221 ttacttgtat aaaatttagt gtttttttca taaggtttat atatgcttgt attctttact
     5281 ttaaaaataa acatatcatt aatatttcga aaaatacacg taattttacc ttttccctct
     5341 tcacactttt cagcagcttc tattgcatta tccaaaagat ttcctaggag tacaacaaaa
     5401 tctatgtctt tcatcggaat tttttctatt tttgaatcta ctttaaaaaa aatattcttt
     5461 tcttccattt ttcgcacttt tatattcaac ataaaattta tttctggaat tcctgtccac
     5521 gctactccac tatatctaat gctttctctc ttgtaatgat tcaaaaaagt aatacatgaa
     5581 tccagttctc cattttccag gcattctttt atatataaaa gcaaatgttt ttcatcgtgc
     5641 accaaacacc gataccggtc atatgacatt ctcaattctt catattcttc ttccattaat
     5701 ttgcatctca tatctaaaat ctgatttctc atttctaggg tctttttttg aaacttaaca
     5761 tatacaccaa tcaatgctat attactaact gctaataaac atgcggtcat tacaaaattt
     5821 tcctttttaa tcgtaccaaa tttgtatatg atgctaacta ttaataaaac atactctaac
     5881 aatccaataa taaaaagttc cttcagacgt gtacgcaata ttccttttat actgtttact
     5941 gacaaaataa atttaattat ccaaaatatg aataaacagc ctaaaatcca aaatataact
     6001 tcctgatatg tatgtcctct cggatatgaa taaaaatcat cccactgttt atggttaaac
     6061 acccctgcat atacaacata agcctctttt atcaatccta tattaactgc atagaaaaaa
     6121 ttccaaacat atgcctgttt aaatgtgcaa tcaaagtagc aaaaaacata taatacaatt
     6181 attccactcc caagaataat cattaacaac gattgatatc cagcccaata ctgagcagtt
     6241 aaccaaaata tcatgccgat atataatatt cttcttaaga ccatctcctt tttctttaca
     6301 aaaaaaatat catatataat tcctgcaatt aatccaatta tgtatataca aataactttt
     6361 atgacatatt tttctatttt tttatcaatc tgccataatg aaacagaaaa attataaatt
     6421 ccaaaaaaaa tcaaagaata caacagccat tctagaacat aatatttttt ttctaatatt
     6481 cttcgttcag aaaacgtctg gctaaatatc cagacaccta tccctgtctc cataaacgtt
     6541 gccagtccat acaataaaac tttcagcatt cttcataccc cccagtaatt cagaattgct
     6601 tctctgacac ctttgaatct ttctctgcca actgtaataa tattaccgtc ccgcatataa
     6661 agatcccttc ctttcatctt catcacatgt tggatgtttg caagatatcc tctgtcagat
     6721 ataataaatt cttttgaatt cagttctttt tctattgttg acagacttgc tctgatcttt
     6781 acttccccac gcctgtgcac aaaaatcaca tattttcctt cttttttcat atagaaaata
     6841 tcagaatatg ccagtttttc aacttcgttt cttttattta tgatatagta ccgctcttct
     6901 ttctccataa ttacaggaag aagcgcatca taagcctgcg aaagtttttc cttcagacac
     6961 tctttgggga tataacgata ggtgtttacc tcatatgctt ctattgcata atccacaaaa
     7021 tttgtaataa atataataac cggattcgga taaagtctgc gtatctctct tgctgcctct
     7081 attccgtttt ctcccggcat ccggatatcc agaagataca tatcgaattt ttcttccttc
     7141 aatcccagca gaaaccattc cacattctgg tatgtcgtta ccgtacaatc tatatttttc
     7201 tctgcaaaat agtgttctgt aatctccttt tcttttttca gatacatttc gtcatcatcc
     7261 agaatcatta ttcttatcat agcaattatt cctccatgaa tgtataaaat ctgaatttct
     7321 tcacatcata aaaataactt tcatccttat tgatgaccag ctcataaacc tcgatatcct
     7381 ctttggttgt cacatcagtt ctgtgatact gataaatgta tctgccttcc tcatgatttt
     7441 ttacctttct gatgatatca tccaccaatt ctccgattgt catcggactg tctctggaag
     7501 gtctccatct tccaatcata ccacgaacct gtgatctggt cagtttaatt ctctttccaa
     7561 gaagatatcc tttcgggaaa aagtcttctc tggtctttcc tgtctttttc aatatctcac
     7621 atatcgtctt attttcttca tctaaagcaa atcccatatt agcataagcc tgcatatgaa
     7681 gcaacgctaa ttcgagatat ttactgtttt cagattcttt attccataac agtaatttgt
     7741 ccagactttt atatacagtt tctctgattg taattccctg attttgcaaa gtctgcaaag
     7801 aaaacatcat ggtatacaaa tcctttgtat attcgtccat attcctatat tcctcctgtc
     7861 ataaaacata tcaaatttga ttagtcactt gtcatttata tccttataca tatttaattc
     7921 cgtctgttaa actttatcaa aggaaaggat ttttatttat gaaaaacaat actatcggaa
     7981 aaagaattgc agaagctcgg atcaacagga atattaccca ggaacacctg gaagaattaa
     8041 gtggtttatc tgtaagtacg atcagccgga ttgaaacagg taagtatatg cctactatcg
     8101 aaaatctcct taagctttct gaaattcttg atgtgggact tgactatttt ctttatgatc
     8161 tgcttcctca taataaagat attcaaagcc cggctattca ggatgcgatt tcaatcatga
     8221 atcaaatggg tgaacgccag actgaataca ttgtaaaaat actgaaaata tatcaggcct
     8281 ctcatcagga ttaaatataa ttacaattcg acaattttcg tgtttttgtc ctcgaaaagc
     8341 atttttctga cctcgaagca acaatcagga aatgcttttt atttttttct gtttcatgtt
     8401 tacatttttc ccttttctca ctctttataa gatgtatcac cggtgagcaa ataaataatc
     8461 aaatttcagg aggatgaaaa aatgacaaaa acagaaaaag cagtaacatg ggcaattaga
     8521 atcgcaaacg atccggcaca cggatatgat caggataaca gatggggacc ggactacgat
     8581 tgttcttcac tggtaatctc cgcatggcag caggctggtg ttcctgtaaa aacaaaagga
     8641 gccacttata caggaaatat gaaatccgtt tttctgtcct gcggctttaa ggatgtaact
     8701 tccaaagtta atctcagcac aggaagtggc atgaaacgtg gcgatgtatt attaaacatc
     8761 gcaagtcata cagtaatgca cattggtaat ggtcaggtgg tatctgccag caaaaatgaa
     8821 aataatggat atcatggtgg taaacccgga gatcagagcg gaaaagagat caaacttcag
     8881 agttattaca atttcccctg ggattgcgtt ctccgttata ctgaagattc ttcaactact
     8941 gatcctgatc ctgaacctca gccaactgca ggaaatgcaa aaatccgcaa aggtcagggt
     9001 tatgccaata aattcgccaa tgcaggaatc tctattaccg gaaaaagaga cgctgctacc
     9061 aaaaaagcag gcgttaaagt tcttcagaca gctctgaaca gggattatgg tgccggtctg
     9121 gatgtagacg gtatctgggg aacaaacaca gacaatgctc ttggacagca ttatgtaaaa
     9181 aatggtgaaa cacagtatat ggtaactgcc gctgagattc tccttctttt acgtgcttat
     9241 gatccaaacg gtgtagagat tcccggtacc tttggctcag gacttctctc tgctgtaaag
     9301 gcattccaga aggcacaggg cttaacagtt tccggaacct gtgacagaaa tactttcctg
     9361 aaactgatca gctgatcttt accagataaa catccggcag aattctgtcc cctgattctg
     9421 tcggatatac cccttcacta ttcatgtata taacaaaaag aagcaatttt gaaacccatt
     9481 aaaatggtct caaaactgct tcttttcgca tttttatatt ctaccacgga acatattcgc
     9541 cgctgtcttc atcataataa taccagccgt ttcctctgcc tacaggacta cagtcagatt
     9601 ccgcagcctg aaacggtata taggaattgg ttcccggatc ccaggaatac aggtcatacg
     9661 gatctgtgac ctcttctgat gcatcgtgag gtgctgtcca gtaatattta ttgccatcct
     9721 gatctgtgac accattttca tttaccatag catcttcaat atcttcccag cttccatagt
     9781 aatttccgtc actgtcatac cagtttccat catcagcttc agaaatcagc cttccatttc
     9841 cctcactgtc atatatcatt gcctgatctg ccctctgatc agattgagta ccaccattac
     9901 ctgttgaacc attatcttca gatgcagaag tgtccacccc tgtggtctgg gaatcgtctg
     9961 tatcagttcc cgcagtactg tctgttccat tctctgaatt ctgtacgtcg cctgcattat
    10021 tggatgaagc agatattttc gtcttcttat ccgcagtctg atttgaatct tcttttccaa
    10081 tggatgtact tttatttacc tgttttttat ccggctgaga tttttctgct gttttttgtt
    10141 ttgtctgttc ggatttctcc tgtgagttct gcgtataatc aacctgtgtc tctgttttat
    10201 tctgttccgc acagccagtc atagcagccg ctgctgctaa aatccctgcc ataataattg
    10261 caatcttttt ctgcttcatt ttgttatcct ttctacattt gttaaaaatg tcgatgcctt
    10321 tatcataatg tgcttttcct gttcattatg acatacttca caggcttcga tgcctcatat
    10381 gtcccttatc tgtcatgaaa tgtaccccat ttttttccaa aatctttacc ccataatttt
    10441 gccttataaa cgcttggtaa aaggggaata tcttttttct taaaagtgaa atctctgtga
    10501 aacaaatggc agcagtactt atttcacaac tattttcttt attttcgacc atttcgtata
    10561 actttttgca taacctttta cataggcacg tcctgcaagg tagtagactc cgggcttcac
    10621 atttttaaag accaccgtgg tttttgtctg atttttcttt gtgtaagcat aactgcttac
    10681 accagtatag ctgccattat cagatttgga aactttcttt gccagtaccc agtctgttcc
    10741 atcacaggac tttggaacag taaacgtcac cgccacgttt ctttttgttc cctgtctgga
    10801 aaccttagct gatttaacag caggttttcc tgttacaagg cttgttttta cagttacctt
    10861 cctgacctct gcccatttac tgagcacttt ggtattgctc ccattcagat atttataagc
    10921 atgtacgcca atataccacg ttcctgccgg tacgccccgt aagataagct ctttactgct
    10981 tccggaatac ccactcttta cctttatata atccgatggt tcttttccgt tcttacttct
    11041 ggcagcaaca acatcgtaac cgtccggttc ctcacccttg ctgttaagta ctattctgac
    11101 atcatttttc ttcacctgca ccttctgaac cacaggtgcg tccggagtct ttgcctttac
    11161 cgtaaccgga accccgtctg accattcccc atattccata acatggctgc tgttctcttt
    11221 gtatgccctg caataaagac tatgtgttcc ctccggaata tacttcagct caggatattg
    11281 attcagttca gaatttgtaa tttttgtctg cgcagtataa ttcccctttt tcagatcctt
    11341 ctgagatttc gctgtcacaa actgatagcc gtccgcttca ttggaaagat ctctcagata
    11401 aagcattgca taatttgtga tcactctggt ccaccgcgta tcaataactg gtctgtttaa
    11461 tgtctgataa gcatccacct gtaccattat ctgtacggca gtgtccagcc cttcattatt
    11521 ttcatcctca ttcagttcca gagatccgtt gaccagaaaa ctttgagctg ccttgctttt
    11581 cggatcataa gcacaattct ccacatccca cttcacagac gcagaaaatg ttgttttctc
    11641 tccattcacc tcggcgccat agacttccag cgacttcggc agatgcaaag catcagcagt
    11701 tttttctgca ccattggtaa ttccggtcac aggcgcaaca gcatctgcca gtccctgata
    11761 agtccggtct cctacaataa aagaattata cagattctgc gttgtcaggt gttctcctgc
    11821 cactgttttc gcagtcacag tcacctgaaa actatatttt cccaccgaaa gccccagttt
    11881 gggccagagt ctcagttctg tgctctcccc aggtgccaga taagcatttc cagataataa
    11941 cacactacat tctttactac ggttaaaaga cagcttcata tctgtatcag taacattttt
    12001 cagaatatat gtctttgctt ccggaagtgt cttatagccc cactgcattg tcggaaaacc
    12061 cccggcagac ttttcagtaa tttccagctg cttcttttct gtcggattct tctctctgtt
    12121 cattgtaaca tgaagaggat atctgcttcc gtcatctgcg agaaatgcaa acgtttcatc
    12181 ataaattccg tattcctgct tcggcaatat ataaaaataa agcgtttctc ccggtttcag
    12241 cagctttttg gaatcctgtt cctcataatc ttctgtccac tttgccatct ggtcatccac
    12301 ttcaaaattc ttaagaccag aagtatctat ccgtattctg gtttcctttt ttcctgaatt
    12361 tctgaccact acatacttct ccacacgaaa ttccgggtca tagaaatcgc tttctgtaaa
    12421 ttcttcttct gtacctgttt ctatactcag ctcataatct ttttcagagg aagctcccac
    12481 aattactttc agagtaacct tacaggaagc accctctttt gtctcaaatg tcactgtctc
    12541 ttcataattt ccggcaggca gattcttctt atcatcaatg tccacagccg cacaacttcc
    12601 gggctgcatt tcttcatccg tatttgtatc gaaaatcggt gcgtaggaaa aatcaaaata
    12661 tctgctctgc ggaaaatcag agagatgaag cgaatctgtt cctgcattat aaagaaataa
    12721 ccgcttacgt gactgttctc cctctgcatg aattcccaga ttgatcaaag cagtacctga
    12781 tgtcagctca tactgcttta taacaggttc ctgctcacgc tgtgcaacat aaaggctcag
    12841 ttcctgtgaa gaaactccaa taccattgtc cgcctgtaca gtaaagctga aactcccttc
    12901 cttctgcggt gttccgctga tcactccccc ggaagacaac gtaagtcccg ccggaagctc
    12961 gcttccctcc tccagactcc agctcacatc tgtatcagct tcaagctgta cctgatattc
    13021 tgttccaatc tctccacccg gcagaaccat atctgtcaat atggcaggaa tactccctgt
    13081 tccatcactg aaagattctc ccgccgaaaa aacttccgcc ccgcatactg ttaacggagc
    13141 tgctgctgtc ataattgccg ataaaaaaac tgctgtaaaa attttgtaat tacttttcat
    13201 tcttctcctc cagataataa aatataaaag tatcaattta cctaattaat attaatatac
    13261 cactggacgg gaatgtttct gtaattacgg aatgacatgt tgtataatgg tcatgaatat
    13321 cagaaaagcc agtaatgttt cgggtatatg tcaaaaacat tactggtctt ttttataaga
    13381 ttattccaca ctttttattc gatacaggga atctcataat tccaggattt acggatgtcg
    13441 tccatgattt tcatgatcct tattgtttcc gcatgaggca tttccggaca ctccgttttt
    13501 ccctcatgaa ttgctttcat gcaggattct acctcatatt catatcctga gatctgttcc
    13561 ggcacaacat aagaagccac ttctttatgt tcggtatcaa acactgtaat cttttccgga
    13621 ttattgatat tctgcacctg catatatcct ctggttccga aaatacttcc cattctgtct
    13681 gagatttctc ttgctccaca ctgaagggtt gccatgcggt ctccctcaaa caccatggca
    13741 atgctgtcca gaatatccac tccattctga aagattgcag tagcctttac atcctttacc
    13801 ttatcgccaa gcaccatgga ggcaaaattg atcggatata cgcctacatc cagaagagca
    13861 cctcctgcaa gctccggttt acggatacgt tccacatgac ttactgtata gctgagattc
    13921 gcggtaactg ccgtaacttc tccgatcaca ccactttcaa taatatcgtt gatcatcttt
    13981 ctggacggca tatatcttgt ccagattgct tctgtgatca gaagcttttt ctcttttgca
    14041 aggtcaaata atttttgtgc ctgctctgca tttacagtaa atgccttttc acaaagcaca
    14101 tgctttcccg cttccagaca cattttcgca tgcagataat ggtgtgaatg aggagttgcg
    14161 atataaacca gtccaacctc atcatctgcc agcatttcct cataggatcc atatgctttt
    14221 tttacttcat atttctgtgc aaatacccgg gcacgttcca gatcacgagc agcaaccgca
    14281 tacgcctcca catctttcat tcctgccact gttttcgcca tagtagaagc aatgcctcct
    14341 gctcccagaa tacctaactt cattttactg tccgttactg aaaacttata aaaagttata
    14401 aacttctatg ttccattcct acttcaacga gtatgctttt gatgatataa atatcaatct
    14461 actcacaagt tcctgtactc tccataggcg taaattccgg actaacgtat ccgtacatat
    14521 ttgcattaac gtttcagtgt cagcttgcaa atttttctcc ataagtcttg agatttatag
    14581 atgcctggaa atctctgtca atcatattcc cacacgcaca tctataaact ctgtcagata
    14641 acttcagatc tttttt
//
