LOCUS       c00048_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCHBICEK_79.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:06:41
            Original ID  :: gnl|Prokka|MCHBICEK_79
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 54557
            Orig. end    :: 77806
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[64557:67806]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1548..3005
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_56"
                     /sec_met_domain="FGGY_C (E-value: 4.8e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 1e-79, bitscore: 259.7,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFIQSMEGMKELTKDIDRTQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3117..4052)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg48_57"
                     /sec_met_domain="LysR_substrate (E-value: 2.3e-33,
                     bitscore: 107.5, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.6e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4168..5592
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_58"
                     /sec_met_domain="Lyase_1 (E-value: 1.7e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 2.6e-21, bitscore:
                     68.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRRLILKEKLMDDDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5701..7386)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_59"
                     /sec_met_domain="FTHFS (E-value: 3e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLIEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKRVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_60"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.7e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.9e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_61"
                     /sec_met_domain="Spermine_synth (E-value: 2.2e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.3e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_62"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 2.7e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.3e-35,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_63"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.4e-14,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDMEELDRICDHIIFNS
                     TAQLKKFKEVCTRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLPEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_64"
                     /sec_met_domain="PAD_porph (E-value: 4e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15406
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_65"
                     /sec_met_domain="CN_hydrolase (E-value: 2.4e-56, bitscore:
                     183.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPRGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKISGMNFGSVTENGVNSN"
     CDS             15551..16012
                     /locus_tag="ctg48_66"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16216..20925
                     /locus_tag="ctg48_67"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVEYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEILVSQTKQDVKAVNVVITDELPSCLQLLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASAESNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQRQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGEAETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSVTPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYSGGYGSYQGGSM
                     AGSSKTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20922..21809
                     /locus_tag="ctg48_68"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAGPK"
     CDS             22001..23092
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_69"
                     /sec_met_domain="Peripla_BP_3 (E-value: 3.9e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 gacgtgcagc aatcaaggaa acttataaag gtgaacttta tgaatgtcct gtaactgttg
       61 agaatgaaaa ggatatggag aaagctcttg aagatgtaaa caaagcagag tgtaatgcgc
      121 tggttgtttt ccttggaaac ttcggacctg aaactcctga aactctgatc gcagagagat
      181 ttgacggacc ttgcatgtat gtagcagcag cagaaggtga cggcgatatg atcaacggca
      241 gaggtgatgc ttactgtggt atgcttaact gctcctacaa cttaaaaatg cgtcatctga
      301 aagcatatat tccggaatat cctgttggaa cagcagatga tattgcaaag atgatcgctg
      361 atttcgtacc ggttgcacgt gcagtcatcg gtgtcagcaa tcttaagatc attacttttg
      421 gaccgcgtcc acaggacttc ttcgcatgca acgcacctat taaaggcctc tatgagctgg
      481 gcgttgagat tgaagagaac tcagagcttg atcttcttgt ttctttcaaa gagcatgaaa
      541 atgaccctcg tatcccggaa gtttgtgcag atatggccaa agagatgggc gaaggcaaat
      601 attatgctga ccttaatgtg aaaatggcac agtttgagct tacacttctt gactgggcag
      661 aggctcataa gggagcaaga aaatacgttg catttgctga caaatgctgg ccagcattcc
      721 cgtcacagtt tggatttgaa ccttgctatg taaacagccg tctggcttcc agaggaatcc
      781 cggtatcctg tgaggttgat atctacggag cactcagcga gtacatcgga ctttgcattt
      841 ccaatgatgc agttacactg cttgatatca acaactctgt tccacagtat atctatgatg
      901 aagatattaa aggaaaatac gattataagc ttactgatac atttatggga ttccattgtg
      961 gaaatactcc tgcatgcaag atgtgtgatt ccagagctgt taaatatcag ctgatccagc
     1021 acagacttct tgagccggca ggatctgaac cagacttcac aagaggaact cttgaaggtg
     1081 atatcgctgc atctgacatt acattctatc gtttacagtg caattccgag ggcgagctgg
     1141 tttcttatgt tgcagaaggt gaagtactgg atgtacctac aagatcattc ggtggtatcg
     1201 gtattttcgc aatcaaagaa atgggaagat tctaccgtca cgtactgatc gagggcaact
     1261 atccgcatca tggagcagtt atgtttggac attacggaaa agcattctat gaggtagtga
     1321 aattccttgg actggatgtt aagaagattg gatataacca gccggcaggt gtaagatacc
     1381 cgacagaaaa tccatggggt taatgagaaa tcagtaaaac ggattattaa tgttcatgtg
     1441 aagtgaatga atctgaatac agaataaata aactgacact atattaaagg catcccgggg
     1501 gtttaccctg ggatgtatta gattagaaat agaaaaggag agcacttatg tattatattg
     1561 gtattgacct tggtacttcc gctgtaaaac ttcttcttat ggaagaatca ggaaaaatct
     1621 gtaacatcgt atccagagaa tatcctttat tcttcccaca tccgggctgg tctgagcaga
     1681 aaccggagga ctggttcata cagagcatgg aaggcatgaa agaactgaca aaggatattg
     1741 acagaactca ggtagcagga atcggttttg gcggccagat gcatggtctg gtaacacttg
     1801 acaaggatga taatgtgatc cgtcctgcaa tcctctggaa tgacggacgt acaggcgaag
     1861 agacagaata tctgaataca gtgatcggaa aagacaaact ttcacagtat acagcaaata
     1921 ttgctttcgc aggcttcaca gcaccgaaga tcctctggat gcagaaaaat gagcctgaga
     1981 actttaagaa ggtagtaaag attatgcttc ctaaggatta tctggcatat cgtctgtccg
     2041 gttctttttg tacagatgtt tctgatgctt ccggtatgct tcttcttgat gtgaagaacc
     2101 gctgctggtc aaaagaaatg ctggagatct gtggaatcac agaagagcag cttccgaaac
     2161 tgtatgagag ttgggaagta gtaggaactc tgaaacctga gattgcgaaa gaacttggat
     2221 tcagtgagaa tgtaaaagtt gttgcaggtg caggtgacaa tgcggcagct gctgtaggaa
     2281 caggtacagt tggtgacggt cagtgtaata tttctcttgg aacatccgga actgtgttta
     2341 tttccagtaa aaactttggt gtggacgaaa ataacgcact tcattctttc tgtcatgcag
     2401 atggaagcta tcatctgatg ggatgcatgc tcagcgcagc ttcctgtaac aaatggtggg
     2461 cagaggagat tcttcagaca aaggatttcg cagcagagca ggctccaatt cagaagctgg
     2521 gagagaatca tgtattcttc cttccatatc tgatgggaga acgttcacct cataataatc
     2581 ctgatgcaag aggtgtattc ttcggaatgt ccatggacag cacaagagca gacatgacac
     2641 aggctgttct ggaaggtgtt gcctttggtc ttcgtgattc cctggaagtt gcaagaaacc
     2701 ttggaatcaa gattgagaga accaagatct gcggtggtgg agctaagagc ccactgtgga
     2761 agaagatcat tgcaaacgtt atgaacctga aggttgatgt tctggagaac gaagaaggac
     2821 cgtccatggg tggagctatg ctggcagcag taggctgtgg tgcttacccg gatgtagaaa
     2881 ccatcggtaa gaaatttgcc aaagttgttg atacggtaga accggatcct gaactggttg
     2941 caaaatatga agagagatat cagaagttca gaactctgta tccggcgatg aagccattgt
     3001 tctaatcgaa tatctgcctg acatactggg gttgttgtgc ttatttagca caacaacccc
     3061 attttgacgt acatctgatg atgaccaatc accacagcct atttgattat gacatatcag
     3121 gaaaagggca gcttcaggaa ttcttccatg gctctgctga tatagcggcc tttcttccag
     3181 taaaaaaaca cagtgcgttt actgctctga ccgggcagct tataaaaaac aagttctgaa
     3241 tttgttggaa ctctggagag cagaagatcc ccgatgaaag tgatacccat tcccaaacat
     3301 gcaatattat aggcagtcat ctgctgatct aggcgaaata ctacagaagg cgaaaagtga
     3361 ttttcctgac aaatggtaag tgcacgctta ccggtatcat tatctgaacg aagaataata
     3421 aatggttcgt tctcgaattt gtttaatgga acagaaggaa tatgagaaga acggaactgc
     3481 ccgttccgga tttcctcaat aggaatctga tatttctgca gtctggtatt tactgaataa
     3541 tttttgggaa ctgcaagaag aagttgttct ttctggtaga tataacgttc aaaaatctgg
     3601 ttatccagaa tacagttatc aatcaccaga tctaactttc cagcctggag aaactgggat
     3661 agttttgctg tactttcttc tacaagagaa atttgaacat gggggaattt ttgggaaaaa
     3721 tcagcaataa ggggaggcag aatccacgaa gaaaaaaagt tactgccacc tacattaaga
     3781 gttcctgttt tgagatttcc cagatccagt aggtagtttt cgagattatt ttcaatatcc
     3841 atgacttttt caacagcctg tatataatgt tttccaactt cagttaactg caaaggtttg
     3901 gtacttcgat caaaaatagg atagccaata cggttttcca cacgttttac attggcgctt
     3961 aaagaaggct gcgaaatgaa aagagcagca gcagctttgg aaaagctttt ttccttgtag
     4021 acctcataga tgtattccat tccctgaaac atataaactc ctccgatata taatttaaac
     4081 actatatatt ttataaaaat atatgtattt gattatatta tagcagagat atataatgag
     4141 ggcaaataca tgggagggcg aataactatg aaaaaaacag actatcgtgt agaaagggat
     4201 tctattggtg taaaggatat tccggaagat gtatattatg gagtacaatc cttacgtgcg
     4261 gctgaaaatt tccacattac ggggctgaat atgcatccgg aaattattaa cagtcttgca
     4321 tacataaaaa aagcagcagc gataaccaat tgtgaggtgg ggcttcttga gaagaaaaaa
     4381 gcacaggcga ttgtccaggc atgtgatgaa attgtttcag gaaaattcca taatgaattt
     4441 attgtggatc ctgttcaggg aggagctggc acatctttaa atatgaatgc caatgaagta
     4501 attgcaaatc gcgcgattga gatactggga ggaaaaaagg gcgattatac aattataaat
     4561 cctaacgatg atgtgaattg tggacagtct accaatgacg ttattcctac tgccggtaaa
     4621 atgacttctc ttcgtttgtt gcagaatctg aaaaaacagc ttcttcgcct ctatgatgct
     4681 cttaatgaaa aagctacaga gtttgatcac ataataaaaa tggggcgtac acagatgcag
     4741 gatgcagtac caattcgtct gggacaggaa tttaaggcat attcggtagc aatcatgcgt
     4801 gatatccaca gaatggataa agcaatggat gaaatgcgga ctcttaatat gggaggtact
     4861 gctatcggaa caggaattaa tgcagatgag ggctatctga gaagaattgt tccaaatctc
     4921 actgaaatat cgggaatgga ctttatacag gcttttgatc tgattgattc cactcagaat
     4981 ctggatccat ttgtagccgt ttccggtgct gtgaaagcat gtgcggtaac tctttccaaa
     5041 atgtcaaatg atctccgtct gatgtcctcc ggtccacgta ctggttttgg ggagattaat
     5101 cttccggcaa aacagaatgg ttcctctatt atgccaggta aagttaatcc ggttattcct
     5161 gaagtagtga atcaggtggc ttttaatatt attggtaatg atgttacgat tactatggct
     5221 gcagaggctg gtcagctgga attaaatgcc tttgagccga ttattttcta ttgcatgttt
     5281 cagtctatcg atactcttgg ctatgcagtc cagacattgg tagataattg tattgtagga
     5341 attacggcaa atgaagaaag atgccgttat ctggtagaaa acagtgtagg tattatcact
     5401 gcaatcagcc cccatcttgg atatcagaag gctgcggata ttgcaaaaaa ggcaattaag
     5461 acaggcgaat ctgtaagacg tctgattctg aaagaaaagc ttatggacga tgatgaactt
     5521 aatcgcattc tggatccgat ccatatgacg gaacctggta tttccggaaa agattatctt
     5581 ataaaaaaat aaagaaaaaa acaggcggga aaatcttccc gcctgttaaa tcgtctggac
     5641 acatatcata cataaatatg atttttatat ttttgaatta ttcgattgat ttcaaccgga
     5701 ttagaacaga cctgtgatct tacctgtctc gtctacgtcg attctctcag cagccggaac
     5761 tttaggaaga cctggcattg tcatgatctc gcctgtaaga gctacgatga atcctgcacc
     5821 agcggaaatc ttcaggttac gtactgtaac ttcgaagtca gtaggagcac ccagtttggt
     5881 ctggtcatct gttaagctgt actgagtctt agctacacag atcgggcagt tgccgaatcc
     5941 aagagcttct aactgtttcg cctgtttctg agcgttagct gtcagaacta ctctcttacc
     6001 gccatatact ttctgaacga tctggttcag tttgtcttcg atagaacctt ccagttcata
     6061 tgcataggag aagtcgtttg gttcttcaat aagacggata acttcttctg caagtttgat
     6121 tccgccttcg ccgccttttg cccatacttc agaaagagca acgttaacgc ccagttcttt
     6181 acatttagct tctacaaagt caagctctgc ttttgtatct gtagggaatg cgttgatagc
     6241 aacaacacat ggaagtttgt atacgttttt aatgttggaa acgtgtttta acaggttcgg
     6301 gatacctttt tcaagagctt ccaggttttc attgttaagg tcagctttag caacgccgcc
     6361 gttgtatttc agggcacgta ctgtagctac gattacaact gcgcttggtt ttaaaccagc
     6421 catacggcat ttgatatcaa ggaatttctc agcaccaagg tcagcaccga aaccagcttc
     6481 tgtgattgca taatcagcaa gcttcatagc catctttgta gctgttacag agttacatcc
     6541 atgagcgatg tttgcgaatg gtccgccatg tacgattgca ggaacgtgtt ccagagtctg
     6601 tacaaggttt ggtttcagag catcttttaa cagggctgtc atagcgcctt ctgcgtgaag
     6661 gtcacctgct gttacaggtt tctgctcgga aacttttccg tatgtatatc cgatgatgat
     6721 cttggataat ctttctttca ggtctttgat gtcgcttgca agacagagaa ctgccatgat
     6781 ttcagatgca actgtgatgt cgtatccgtc ttcacgaggc ataccgtttg tctttccgcc
     6841 aagaccatct actacgttac gaagctgacg gtcgttcata tctacacatc ttctccatgt
     6901 gatcttacgt gggtcgatgt ttaatgcatt gccctggaag atatggttat cgatcatagc
     6961 tgccagtaag ttgttagctg cgccaatggc atggaagtca cctgtgaagt gaaggttaat
     7021 atcttccata ggaacaacct gtgcatatcc gccgcctgct gcaccacctt ttacaccgaa
     7081 taccggtcct aaggatggct cacgaagagc taccataaca ctcttgccaa gtctctgcat
     7141 accatctgca agacctacag tagtagtagt tttaccttct cctgctggag ttgggttgat
     7201 agctgtaacg aggattaatt ttccatcctt cttatcactt tctttcagaa gattgtagtc
     7261 gatttttgct ttgtattttc cgtactgctc cagatatttg tcgtcaatac ctgctttctc
     7321 tgcgatctga gtaattggaa gcatctcgca ttcctgtgca atttcaatgt ctgatttgaa
     7381 tcccataatt gtttttctcc tttcgtttcc gcataacatg aaaaacttct gttgctgttc
     7441 actccgcgat cagcaacaat tattaattga aagaagtatt ggccggtctg cctggtattc
     7501 ctgatttctg ccctgaaagt tataaaaaaa ggccagtatc tgaatatttc aaatactgcc
     7561 cagacggtcg gctcccacaa acctccgact ccacgtggtt tgcactccac tctttccgtc
     7621 agtactcgaa ggttctttca attgatgaat acaatatatc attttgagaa aaaaatgtca
     7681 agaaaatttt tgttgaaacg tcaaaaaatg tgagtaaact ggataaaagt tgtgcaaatt
     7741 gataagagaa gagaatcgta atccctggtc atgaaagaaa atacgttttc tcaaggaaag
     7801 aaattgttaa aaaataaaca cagttttccc tgataaatga agaaaatata aaaagcgggt
     7861 aaagactgtg caaaatatgg aaaatggaat tgacaacagt tcagaagata tgttattctc
     7921 atctttagta tgaaaagaca ctatcgtttt catgcaaata tttgctcaca ttcagagaca
     7981 gtttctgaat gttaagccat acggacaggc ggggcagttg ccgggtggga gacaccacat
     8041 tattgattga gttagaagct caaattttat aagttgatta ctttataata atcagtgcgt
     8101 aagcacacat catcttgtga aacggtcaat aagagcatag catatatttg ccagcgattg
     8161 aagacgacag cagtcatgaa tatttcagaa tacgggaaca ggcacaggat acagacggat
     8221 ttatacggga aatccggtca gtgtataaaa agacagagcc tgagaaattc tatagatcat
     8281 gagagaagca gatggtgaat gaacttatct gcttcttttt tgtgcggata tagcagatat
     8341 aaaggatatg gttggagata aacgctttgc ggggatgtgt agcgattcta tagaatcgtg
     8401 tgccgagtct cacatgcgtt cgacttgaat atatagagaa ataattgaat cattgtgccg
     8461 gttttgagcc agtatacaat tgctgtatga ttgaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagcttc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa accgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatttg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagattgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccatagg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaata tcttcaggtt ctgaaagggg gtatctgatt atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaga tggttacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg attagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgaaaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgct tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggt ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatt
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgccct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatggag gaactggatc ggatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaggtgt gtaccagagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcag atgacctgga
    12661 gaaaacatta caggcggtag aggagaagtt tggagaattt ctgccagagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt aatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agctggggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgatg gactttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccag gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtattacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagct ggggattgtg atcccggtca gcttttatga
    14761 aaaagaggtc aataatacct ataacagcgt tgcggttctg gatgcagatg ggaagaatct
    14821 cggcgtttac cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gataccggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggagcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgcg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccagaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 tagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaatttccgg
    15361 aatgaatttt ggctcagtta ctgagaacgg agtgaacagt aactgagttt ataagaattt
    15421 cataaaaagt ttatgattat attagttgct acctgcggta tatatggtaa aataagagta
    15481 cgaacgttac tgataacgga gcgagcagta gagttttgac atgtatttct ggcaaaatgg
    15541 agtgtagaag atgaacagaa aagaattttt ggaaatcctg agaagccagc ttgccggtca
    15601 gatgcaggag ggcaaagcag cagcacatat caggtattat gaagattata tacagtctca
    15661 ggtacgtggc ggacgttcag agcaggaagt actgcaggaa ctgggagacc cgcatctgat
    15721 agcaaaaact ctgatcgata cagatgatgg aagtacacag gaagattacg gagagtattc
    15781 ttcttatgga agcagttatg gcaatgagac agagcttcct catcagcagg agaaaagatg
    15841 gaaaaaagta atcgatcttt ctacctggca tggcagggct gttgttattg cagcggcggc
    15901 tgttataatt gttttactga tactgataat cggagttgcg attccgtttt ttattattct
    15961 tgcaattatt ctttattttc tttcatggct gaagaaaaga aatgatcaat gaaaatctgt
    16021 gcagggtttc agaaaagaaa ccctgcgcag aatcttaaaa atcttaagtg taaacgttct
    16081 tgtttcacga tattaattcc ccttgaatat ttataatcat acaatctcaa cttatttcta
    16141 ttctttaatc ctgccaggtg cagggaaaaa tcccacattc atttttatat tttttgttcg
    16201 gaaaggagac ggaaaatgaa acacaatttc aaactgaaag aacgccttgg agctttgctg
    16261 cttgcaatgc tttttattct gcaggcaatt ctggggcttg tgcctgtctg cgtaactcag
    16321 gcggcaccgt taactgtaga aacatgggac agtgacaagg tggtagagta tggttatcgc
    16381 tttaacatga agtttcagcc cggaattacc acatatgaat cttttgggtg tgataatctg
    16441 gacagggaag ctttttcaga caatggaaaa agcgaacgtg acacagagtg cgttcgtgta
    16501 ggagcggact ataaagccgg aagcgcaggg atgcgttata acaatgtagg aaaagatgga
    16561 aatggaaata ttgttgatgt cagactcatt cttgtgggag tagagaatgc agaaccccgt
    16621 tatgatctgc gcactgcaga atcgattgtt cagaataaag gcggagctac gtttgcatgg
    16681 aaagataatg aagcttatcc aatggttggc ttttccaaaa acagtatcgg tgtatttatt
    16741 tattctgtag gatacgcaaa ggttaagttt cagtttctga agcatggaac agaagaaaca
    16801 ctgccgatca gtggccatgg aaccatacgt gatattgatg cgggacaggg agtccgtatt
    16861 ccgtcagaca gcagtctgga taatgcatat gttctgaaaa acaatgatta tctgacggta
    16921 gatggaaatt ctgtaagctc accccttggt tccgttgagc cggatgatcc gagaggatgg
    16981 ctgaatcttt tttataatac agataatttt acggtagaat tctgtcatca gttcagactg
    17041 gataaatggg ataaaagtcg tgaagatgcc attgcaaaag ccggttctca ggaaagatgg
    17101 gcagagatta caagaaataa atatctggat ccatcaggca acagttattg tccgaacttt
    17161 aaaggacaga aatactgtaa agcatatgca tattttgatt ttacatccta ttgtttcggc
    17221 gatgttgaga tgaaaaaagc acctgagaaa cgtgtgggag aggcaaactg tacatgggaa
    17281 caggcagctg ctgcatcaaa agaaaaacct tttggcattc gtcagggaca ggaatttcag
    17341 tatatgatcc gggcagaggt gacacccaat agactgaaat cctttgtggt acaggatata
    17401 cttgaggatt gtcttactat agaggatgca tcaaaagtca gtattgtgaa tgatgcaggg
    17461 cagacagtga cagactggtt tgatgttgct gttgaaggac agaaagtgac ctgcagggcc
    17521 aaagcagaga gccttcagga tgaagcattt acagataatc agacttacac atttacttta
    17581 aaagtacgcc agagaccgga atcagaaatt aatatttcaa aataccttgc agaggatgga
    17641 tacagtattc ttgtaccaaa ccatgcatcc atgagttatg aacgtacaaa cggaagcgga
    17701 gatacaatgg atacggaaac agtgtgggta aagggtgtga ttccaccgga actggaagta
    17761 aagaaaaata cttctcagta tgaatggaaa acgggagata tcatagatta tgagattctg
    17821 gtttctcaga caaaacagga tgtaaaagca gtaaatgttg ttattacaga cgagcttcca
    17881 tcatgtctgc agcttctgga agggcagtat gctgtagaga caagtcaggg aggtgagaac
    17941 tgtacgctta ccggacaggg agaaaatgga tggaaagcag agtgtccgtc cctgaagtat
    18001 ggggagacga tcacaatccg ttttaaatgt caggcatctg cggagtccaa tggacaggaa
    18061 tgggaaaata ttgtgactgc aacagcggat aatctgatca atcctgagac aggagaacag
    18121 gaatccagaa aggatatggc agaagtatgg ccgaacagtc cacagcttga aattgataaa
    18181 acagcagaca aatatgaatg gcaggcagga gagcaggtag cttaccggat cgtagtgaat
    18241 aatgtaacgg caggaacaat cgcaaaagat gtaactatta ctgatattgg tctgccgcag
    18301 ggactggttc tggcaggtgg tgcacagagc atggaagtac tgggagttca gcgacaggta
    18361 aactatcccg taccggataa gaaaacagga caggcatatg aagcgagacc tgtggattct
    18421 cagttgaatg cagatgagaa cggattttct ttttattgtt cttatgtacc atacagtcag
    18481 cctgtaacga ttattttcca ttgtatcgca caggaagagg caaatggaca cgaaagcgta
    18541 aatgcagcaa ctgtaaaagc tgctaataca gatgagagat ctgatgatgc agaagtatat
    18601 gtaaattcag gagaattctg gattgagaaa tctgcagatc attatgaatg gcaggtcgga
    18661 gaacaggtac agtacaatgt ggtggtggag aataaaaaag caggtacagt ggcccggaac
    18721 gtaactgtct gggataccgg tatgccggca ggacttgcgc tttcatcggc agaggatgta
    18781 tcggtaagcg gaatcccaca gaatattacg cagctgacag cagggaccaa agatgttttg
    18841 aaccagctca atccggaatt ttataatgag acatcagaga aaccggtgaa ttatgaattt
    18901 cttcaggagg gaagcggatg gagactgaac atttcagatc ttccggcaaa tactccggtt
    18961 atgatttctt tcctttgcac agttacggaa gcggcaaatg gaatggaaag cattaatgtt
    19021 gccaatgtgc aggcgcagaa tgcccctgtt tcacaggatg acgcagaagt gtatgtaaat
    19081 acagcagttc tttctattga gaaaagtttt cagaatccat atctggcagc cggggacgga
    19141 cgtgcggaaa atgaatttcg ggtaggagaa caggtgaatt atcaggttac ggttaataat
    19201 cttcagaagg gatctatcgc aagaaatctt gtgatcagtg atctttccct tcctgaaggg
    19261 ctggctctgg acggagctga agatgctgtt actgtaagcg gtgttccggc tgttattcag
    19321 aatccggtgg caggaactga tgatgcagga aatcagctga atccggaaaa ttataaagaa
    19381 acagtggaaa aaccggtcag ctgtcaggtt acacgtcagg gaaccggatg gatcgtgacg
    19441 atttcagatc ttccgtatca gacacctgtg actgttaatt tccgctgtac tgcgcaggaa
    19501 agcgtaaatg ggatggagat tgtaaataca gcacaggcgt atgcagataa tgcacagaaa
    19561 gtaaaggact cctcaaaaat ctgggtgaac tcgcctgttc ttaaagtaga gaagacgacg
    19621 gacaaaccat tttacaaata tggtgatatt attacatacc gcattgtcct gacacaggag
    19681 cagaccggat gtgtggcgcg taatgttact ttgcaggatg tgatcgatac tcagggagta
    19741 cgtcttctga aggattcggt gattctgatg gatgagaaag gaaatgtggc agatgctgat
    19801 gtacagatca atgatgataa tactttcctg atgtcaacag gcaggacact ggtcagggat
    19861 agtagatata gtatctgcga taatgataaa ggcggtcttt ttgagcaggt aatgtataat
    19921 cctctggact gtcaggaaca gaaaagtatg atcgtggaat atcaggcagc agtgattgat
    19981 gcagccctgg caggacagaa agtgcacaat actgcagttg cagacagcag tgaaaagata
    20041 cctgcaaccg gggaagcaga gacagaggta cacagtccga ttctggaaat tgtgaaggaa
    20101 tcagataaga aagagtatgc gtccggtgaa aaaggatatt ataaactgac agtaagacaa
    20161 ctgcgtgagg atgtcacaga tcagaatatt gttatcgaag ataaactgga aacccaaggg
    20221 gcttccattg taaaagacag catttttgtg aagaaaaacg gtatagaact gaaagatgcc
    20281 aaaatagagg cagatgatac aggatttgta attcagacag gagcatcgtt gtcagatatg
    20341 gataaaattg aagtctgcta tgaaatggta tttaaaacag aaagcacaga gcctgaaaaa
    20401 attgtaaaca cagcgaaagc aagaggtgat atttcaccgg aaattactgc acagcaggag
    20461 gcatatgtga aagcaaaagc agaaccgact gccacaccaa caccgtctgt aacaccgaaa
    20521 ccaacagaaa caccaaagcc gacagagaca ccaaaaccta cagaagtacc gaaaccgaca
    20581 gagcagccaa aagccacacc aacaccatct gtaccgggaa cctgcccgaa aatgactcct
    20641 gtaccgacga aagcaccgtt ggcatcttac aatggtggaa ataatggagg aacgacttcc
    20701 ggaagcggag gcagcagtta cgcaaattcg ggtggatatt ccggtggata cggaagctat
    20761 cagggtggtt ccatggcagg aagttctaaa acaggagatg tcagaccgtt taaaatgatg
    20821 gctgttcttg gacttatcgg aatgggactg ctgacaggag gtgtggtgat ctacagaaga
    20881 actgtttccg ggaaaagaaa tataaagggt atgccgcgga aatgaaaaaa ctcagaacat
    20941 ttgcagtaag tatgatcata gcagcaatcg ggcttcttat atattgtgcc ggcttctata
    21001 taaaaagtta tgaacagaat cttgcagcaa ggcaggaata tgcagagctt tcccaaatgg
    21061 caggggtgaa gaacagagaa ggtgccggat tattggcaga tggcaaaaaa actgatgaag
    21121 acagcagtac aaaaaacagt gaaaaaaaac gcaggaaaaa acagagaaga tcttctgaat
    21181 caaaaaacaa aaactgtaca gatgaaatca gggaatcctt cgggatttcc tgggaaaatt
    21241 taagaaagat caactctcag acagttgcct ggattactgt cccgggagcc gatatttctt
    21301 atcctgtagt tcaggcggca gatgatgaat attacctgaa acataatttc agaggagagg
    21361 aagatctgtt tggatgtatt tttctggaac atgacataaa aaagaatttt acagattccc
    21421 acagtattct ttacgggcat aatatagaag gtaatatgat gtttgcaaat ctgaaccgtt
    21481 atgaacagcc tgaatttctg aaaaaatgtc ctgaaattga gatcacaaca ccaaaaagaa
    21541 agtttctgta caaaattttt tctgtggaac aggcatcttc ccaaagcccg gcatttgaat
    21601 atggatacaa gttatccagt cctgcataca ggagacaatt atctatattg aaaaataatt
    21661 ccatgtatga cacaggagta gagcctgatg aaagggagag aatggtgact ctgatcacct
    21721 gtaattcacg tctggataaa gaaatacgta tggcggtaca tgggatttgc catgaatgtt
    21781 atggtataga aaaagctggg ccgaagtgat gttgaaatca atcggatatt ggtaactttc
    21841 gtaaaggatg aactgttact gttcacatat cactatccct cgaggtgttt tggaaaaaac
    21901 taatgaaaaa tctctcgata ttttgtataa tttatgcata aaaaacaact tgttcgtacg
    21961 tgcgtacaag ttgtatccta aatacaggag ggaagaagac atgacagata atggaaagcc
    22021 gaaatatttc tcactgatgg aacagctcag aagtgatatt atgtcaggag ctatccgacc
    22081 gggagagaag cttccttcag aaaacgagct ttcacagaaa tattccctga gtagacatac
    22141 agttcgtaaa gcactgggaa tcctggagca ggacggatat gtagaggcat ttcacggaag
    22201 aggtacttat tgctctgaga atatgcgcca tataaagaat tcaaagaata ttgcggtagt
    22261 gaccacatat atttctgatt atatttttcc gagactgata cagggaatgg ataatgtcct
    22321 ttcagaaagc ggttacagta ttatcctgaa aaacacagca aacagcagac agaaagaggc
    22381 cagatgtctg gaggaacttc tgaagaaaga tattgatgga ctgatcattg aaccaagcaa
    22441 aagtgagatg atctgtaaac atagaaatct ttatcagaat ctggataaat ttgaaattcc
    22501 gtatgtgttt attcagggaa tctattcaga aatgagggat aaacctcata ttcttatgga
    22561 tgatgcacag ggaggctatc ttgtaacaaa atatctgctg gaactgggac ataaaaagat
    22621 caagggtttc tttaaggcag acgatatgca gggactggag cgccacaagg gatatgtgaa
    22681 ggccttacag gagtcaggga ttgcctatga tcctgatgat gttgtctggt ttcatacaga
    22741 ggacaggaaa gtaaaacctg cactgatggc aaaagaaatg gtacagagcg gacagcttcc
    22801 ggatggaatc gtctgttaca atgatcagat tgctgttcag gttatggaag aactggagaa
    22861 aatgggagtc aggataccgg atgatatttc cattaccggt tatgacaatt cactgtatgc
    22921 tcagcgagga agcggaatca caacgatagc tcatccgcag gaaaagctgg gagaaatggc
    22981 agcagagctt atacttgaga agatcaacgg agttcctgaa gaagaaagta aggttgaaag
    23041 actgatttat ccggaactga tcatacgggg atcatgcaga aaaatattgt aaacaaatga
    23101 aataaataaa aaataaaaat aaatccagga ggaattttat catgaaaaca ggaagaaact
    23161 ataagttctg gttttgtaca ggttcacagg atctttacgg agatgagtgc ttaagaaaag
    23221 ttgctgagca ttccagaatt attgttgag
//
